LOCUS       OW969944               11955 bp    DNA     circular BCT 22-MAY-2022
DEFINITION  Klebsiella pneumoniae isolate 11 genome assembly, plasmid: P6.
ACCESSION   OW969944
VERSION     OW969944.1
DBLINK      BioProject: PRJEB42440
            BioSample: SAMEA8158500
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Alioto,T., Alioto,T. and Gomez Garrido,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-MAY-2022) CNAG-CRG, CNAG, Spain
FEATURES             Location/Qualifiers
     source          1..11955
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /isolate="11"
                     /isolation_source="Complejo Hospitalario Universitario de A
                     Coruna (A Coruna)"
                     /db_xref="taxon:573"
                     /plasmid="P6"
     gene            822..2783
                     /locus_tag="AN2345V1_5451"
     mRNA            822..2783
                     /locus_tag="AN2345V1_5451"
                     /note="AN2345v1_5451.mrna"
     CDS             822..2783
                     /locus_tag="AN2345V1_5451"
                     /note="long variant; AN2345v1_5451.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH6294966.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNNRTAPFSVLASLDSPGRMVRVRRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGITWCAGGLV
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVDRREIPLKTFPVLAKTDPLAEY
                     QSEAGRQRPGDDDFAGLY"
                     /name="hypothetical protein"
     exon            822..2783
                     /locus_tag="AN2345V1_5451"
                     /note="AN2345v1_5451.mrna"
                     /number=1
     gene            2783..3514
                     /locus_tag="AN2345V1_5452"
     mRNA            2783..3514
                     /locus_tag="AN2345V1_5452"
                     /note="AN2345v1_5452.mrna"
     CDS             2783..3514
                     /locus_tag="AN2345V1_5452"
                     /note="long variant; AN2345v1_5452.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH6295005.1"
                     /translation="MALERYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQISVWGLTPHGVAFSFDEDEPLTDIIPFQP
                     SRVSAAQLPHRLAVQSLRLAMEARGATGWRYLHRIALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="hypothetical protein"
     exon            2783..3514
                     /locus_tag="AN2345V1_5452"
                     /note="AN2345v1_5452.mrna"
                     /number=1
     gene            3521..4051
                     /locus_tag="AN2345V1_5453"
     mRNA            3521..4051
                     /locus_tag="AN2345V1_5453"
                     /note="AN2345v1_5453.mrna"
     CDS             3521..4051
                     /locus_tag="AN2345V1_5453"
                     /note="long variant; AN2345v1_5453.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH6295042.1"
                     /translation="MALYMVFIEDAEDRDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRTQHLAMIKSIGMYDERLNSDEKATYFFTGENPQWERDKPAGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQISAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKSARRWWPFGKK"
                     /name="hypothetical protein"
     exon            3521..4051
                     /locus_tag="AN2345V1_5453"
                     /note="AN2345v1_5453.mrna"
                     /number=1
     gene            complement(4079..4258)
                     /locus_tag="AN2345V1_5454"
     mRNA            complement(4079..4258)
                     /locus_tag="AN2345V1_5454"
                     /note="AN2345v1_5454.mrna"
     CDS             complement(4079..4258)
                     /locus_tag="AN2345V1_5454"
                     /note="long variant; AN2345v1_5454.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Regulatory protein rop"
                     /protein_id="CAH6295079.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Regulatory protein rop"
     exon            complement(4079..4258)
                     /locus_tag="AN2345V1_5454"
                     /note="AN2345v1_5454.mrna"
                     /number=1
     gene            4327..4704
                     /locus_tag="AN2345V1_5455"
     mRNA            4327..4704
                     /locus_tag="AN2345V1_5455"
                     /note="AN2345v1_5455.mrna"
     CDS             4327..4704
                     /locus_tag="AN2345V1_5455"
                     /note="long variant; AN2345v1_5455.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH6295119.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQGETHERDGLRLPDETEKTASDALIAEIKALREEVAGLRQEMQAMRLLEH
                     KPETAETPAGTPRRWWQWGKR"
                     /name="hypothetical protein"
     exon            4327..4704
                     /locus_tag="AN2345V1_5455"
                     /note="AN2345v1_5455.mrna"
                     /number=1
     gene            complement(4766..5065)
                     /locus_tag="AN2345V1_5456"
     mRNA            complement(4766..5065)
                     /locus_tag="AN2345V1_5456"
                     /note="AN2345v1_5456.mrna"
     CDS             complement(4766..5065)
                     /locus_tag="AN2345V1_5456"
                     /note="long variant; AN2345v1_5456.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH6295156.1"
                     /translation="MPYDVEWKQGAIEDVTMLFDYIAENSSLWDAQNVTDRVLTAADKL
                     ADFPRLYEVDSHYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHTVR"
                     /name="hypothetical protein"
     exon            complement(4766..5065)
                     /locus_tag="AN2345V1_5456"
                     /note="AN2345v1_5456.mrna"
                     /number=1
     gene            complement(5055..5318)
                     /locus_tag="AN2345V1_5457"
     mRNA            complement(5055..5318)
                     /locus_tag="AN2345V1_5457"
                     /note="AN2345v1_5457.mrna"
     CDS             complement(5055..5318)
                     /locus_tag="AN2345V1_5457"
                     /note="long variant; AN2345v1_5457.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH6295196.1"
                     /translation="MSNTTHYENANFLRELAENLPRILPESDPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     exon            complement(5055..5318)
                     /locus_tag="AN2345V1_5457"
                     /note="AN2345v1_5457.mrna"
                     /number=1
     gene            6092..6610
                     /locus_tag="AN2345V1_5458"
     mRNA            6092..6610
                     /locus_tag="AN2345V1_5458"
                     /note="AN2345v1_5458.mrna"
     CDS             6092..6610
                     /locus_tag="AN2345V1_5458"
                     /note="long variant; AN2345v1_5458.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH6295234.1"
                     /translation="MQKVTDLYPPEIARHKLQNHFAGNTVMLELIQKLNKTSLCTFAAL
                     CDGNVVTTSGYNITADLCVNRASAVAHSLKQKYLPVTARTISTKADVGGAVKQAAFCID
                     EDDLARLKSEPEKMMKECERNLNSQKRTNAQKEMSRLYKEFGEDGILALLRNVAQSNGT
                     PPPGAHPAS"
                     /name="hypothetical protein"
     exon            6092..6610
                     /locus_tag="AN2345V1_5458"
                     /note="AN2345v1_5458.mrna"
                     /number=1
     gene            <7512..8999
                     /locus_tag="AN2345V1_5459"
     mRNA            7512..8999
                     /locus_tag="AN2345V1_5459"
                     /note="AN2345v1_5459.mrna"
     CDS             <7512..8999
                     /locus_tag="AN2345V1_5459"
                     /note="short variant; AN2345v1_5459.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Group II intron-encoded protein LtrA"
                     /protein_id="CAH6295270.1"
                     /translation="VMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
                     /name="Group II intron-encoded protein LtrA"
     exon            7512..8999
                     /locus_tag="AN2345V1_5459"
                     /note="AN2345v1_5459.mrna"
                     /number=1
     gene            9104..10792
                     /locus_tag="AN2345V1_5460"
     mRNA            9104..10792
                     /locus_tag="AN2345V1_5460"
                     /note="AN2345v1_5460.mrna"
     CDS             9104..10792
                     /locus_tag="AN2345V1_5460"
                     /note="long variant; AN2345v1_5460.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Colicin-E3"
                     /protein_id="CAH6295310.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVNVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGVKDYGHDYHPAPKTEEIKGLGELKKAPKKTPKQGGGGRRDRWIGDKGRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQIKGPDPKGRNIKKYL"
                     /name="Colicin-E3"
     exon            9104..10792
                     /locus_tag="AN2345V1_5460"
                     /note="AN2345v1_5460.mrna"
                     /number=1
     gene            10802..11059
                     /locus_tag="AN2345V1_5461"
     mRNA            10802..11059
                     /locus_tag="AN2345V1_5461"
                     /note="AN2345v1_5461.mrna"
     CDS             10802..11059
                     /locus_tag="AN2345V1_5461"
                     /note="long variant; AN2345v1_5461.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Colicin-E3 immunity protein"
                     /protein_id="CAH6295324.1"
                     /translation="MGLKLNLTWFDKKTEEFIGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGGFDVEKSWVPLLQPYFKNKIEVDKYWYQISFDYRDGNW"
                     /name="Colicin-E3 immunity protein"
     exon            10802..11059
                     /locus_tag="AN2345V1_5461"
                     /note="AN2345v1_5461.mrna"
                     /number=1
     BGC             4104..11955
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(11397..11955)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.754"
                     /coverage="97.0"
                     /evalue="0.0"
     Typing          2784..3511
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.062"
                     /coverage="100.0"
                     /evalue="1.0000000000000001e-143"
ORIGIN
        1 gccctgccgt tttgcctcac atgttagtcc cctgcttatc cacggaatct gtgggtaact
       61 ttgtatgtgt ccgcagcgcc cgccgcagtc tcacgcccgg agcgtagcga ccgagtgagc
      121 gaggaggcgc aatttccccg gcacctgcaa gacggtcacc ggacgcgctg atgtgggata
      181 ttgtcccctg attaagtctt tctattccct gacgatcaat tatcaggata ggtgaaccat
      241 gtcggttttt cgctgaacat tttacgttaa cctatctctg ttgctttttt ctccttacgg
      301 agaaatgcaa gtcatccccg ctagggcgtg gctgacttca gggggaaatc ccctgcttac
      361 gctggctgga cgccaccgac gcacggtctt tccccctctt tctggctctg tccggctgga
      421 cgccggccac gccagaaatt cacctggccc ccgtcaggct cacgcctgac cacccacaaa
      481 aatccacggt gctgaacgca cctgacgaag cagcaaagct gctcctgatt ttgcgggtgg
      541 tcagccgctc gctatggcga actctgacgg gggccggaac accggaaaag accgcactgg
      601 ggtgctgcct tttcctctca cacgctgggg cgtgctcgtt gttcctccgg ggctgcgcct
      661 tttccgcatg gggcggaaag aggctggcct ccgcggtgaa agctgaacgc aatcaccacg
      721 gacgtgaccg ccgccgccat gccttggggc atgtccgcgg cttgtgcagc aggggctgca
      781 caacacgccg gtaaacccgt cgtctgaagg agagagattg catgtttaat acggattcgc
      841 ttgcctggca gtggcatatc ccggagctgg cccggcagat ttacccgtgg gtcagctggc
      901 tgtaccggga gtattacggt ctggccgggg cttttctggt tatcggcctg tttttcggtc
      961 tggctgaact ctgggccgga cggatgcgtt ttgtggggct gagtcataag gagcggcggg
     1021 agtatgccga tcgctataag cgcgataata accggactgc gccattttcg gtgctggcct
     1081 cgctggattc gcccgggcgg atggtcaggg ttcggcggca tgtctggaac tacgcgtact
     1141 ggctgaccgg cgctgccggt ctggcccttc tgggggggct tgttgtcgcc gtgtttatcg
     1201 agagctgggg agaaaccgtc ctgcgtccgg acctctacgc gaacgcagat tattacctgc
     1261 tgcagccggc taacctgttc gggattacct ggtgcgcggg cgggctggtt gtcgggattg
     1321 tgttggcgcg gctgctggcg ttcctgctgc ttgacggtca ttttgcggcc gctgacgagg
     1381 cggtgaacgc gaaactgaac caggagagcc ggcgcagcag ccagcggacc ggtgaaatga
     1441 ccgacgtccg ccacctgcat ttcggggagc cggtaccggt taacgcgctg gccgattttt
     1501 ccacggagca ggcccggaaa cagcaggcgg tgtttctggg taaggatgag cagggccagc
     1561 cggtgctggt cccgcgtgat acctggcgca agaccaacat tcagatcctc ggcctgcccg
     1621 ggagcggcaa gagcgtgatg gccaccaacg cgctcattcg ctgcgtacgc gatttcgggg
     1681 acgcggtggt gtacttcgac ccgaaagggg acgcgtgggc accgcacgtc ttccgggcgc
     1741 actgcccgga cttcaccctg ctggatctgc ggccggggaa accggcgcag ctgaatctgt
     1801 tccgcgatct cgaccagtac gccctgaaga atctgctggt tgccgggttt aacctgagtg
     1861 agaccggcga cgtggcggac cactaccgca tcagcgagca gaaagcggcg aagctgattg
     1921 cggagcagtt cccgcagggg gcaaacattc agcaggtgct ggcggcggca tacgcgctgc
     1981 cggaggccct gaaaaaggac gtgaaggggc tgatcaccaa gctggagaac gtggccgacc
     2041 tgagcgtcct gcagacggac agcggcatcg acgtggcggg gataatcaac ggcggcggct
     2101 gcctgtacgt catcggctcg atggacgatg aggcggtgat ccgggtgcag aagatgttgt
     2161 ttgcccgctg cgcgcaaatc atcattgcgc gggatgagtt ccggaggtgg ccgcacgcga
     2221 gcatcatgct cgatgagatt aaatatctgc tgtcgaaata cgtgctgaac gcgctgggga
     2281 cgctgcgcag ccgggactgc aacctgctgc tcgcgcacca gtcgctgggc gacttcggcc
     2341 agtgcggcca ggatctgccc gctgattttg tgaaaaccac ggtactggat aacacgccga
     2401 tccgctggtt ctatcgcgcg gccagccagg agtccgcgca gtgggcggcg ggccagaccg
     2461 gggagatccg ggtggacgtg gagcgccgcc gggccagccg ggaggcgggg aacgtggagc
     2521 acatcagcgg cgacagcttc atccagaagg aggcgcggcc gctgtttgac gtgaataccc
     2581 tgcaacatct gcctgacggg ttcgcggtga tgaccgggct gggcgtggcg cggctggcgt
     2641 tcagcagccc gctgcgggtt gatcgccggg aaattccgct gaaaaccttc ccggtgctag
     2701 cgaaaacgga cccgctggcg gagtaccagt cggaggccgg gcggcagcgg ccgggtgatg
     2761 atgattttgc ggggctgtac tgatggcact ggagcgatac aacgtcagcc acgcgaaacg
     2821 gcaggcgcgg aacgcggaga aaacacggct gaccctgcgc tggctgcggg aagagctgtg
     2881 ttccacggcg gagctggttg cgcgacggct ggggattgcg gcggtacagc cggtttaccg
     2941 cttcctggac agcctggtgg cgaaagggct gctggtccgg gcgaaatacc cggttgacgg
     3001 ccgtcagatc agcgtgtggg ggctgacgcc gcacggggtg gcgttctcgt tcgacgagga
     3061 cgagccgctg acggacatta ttccgtttca gccgtcgcgg gtgtcggcgg cgcagctgcc
     3121 gcaccggctg gccgtgcagt ccctgcgcct cgccatggag gcccgggggg ccaccggctg
     3181 gcggtacctg caccgtattg ccctgaaagg gatgaaggtg ccggacgcgc tggcggagct
     3241 ggacggcaga acggtggcgt ttgaggtgga gcgcaccgtg aagagccgca ggcgctatca
     3301 ggaggtggtg tccgggtatc tgtttaaccg ccgggcgaac ggcatcgatg aaatctggta
     3361 catctgcccg gaccgggcga cgcaggtcag ggtgcagcgg gcgatcctgt cggtggatga
     3421 aatcgtgaat ccacagaccg gcgaggcccg caaaacggcg gagctggatc gtgaacggct
     3481 gtttgcgtgc tttaaattta tgacaacgga gtgagggatt atggcgctgt acatggtatt
     3541 tattgaagat gcggaggacc gggacggcga gcgctgcatc atgccgacca gcgagcatct
     3601 tgaagatatg gtggtgctcg cctggcagac cggggcgtat gttttctgtt ttgtcgaccg
     3661 gacccagcat ctggcgatga ttaaatccat cgggatgtat gacgagcggc tcaacagcga
     3721 cgaaaaagcc acgtactttt tcaccggtga aaatccgcaa tgggaacggg acaaacccgc
     3781 aggaatgaag ctgtgtgatt acctctatcg caaggtggag cggttcgcca tcgagaacgg
     3841 tgtgcaggtg gttgatgccg ggaagtgctc accggagcag attagcgcga tgattgaggt
     3901 ggtcagcgag cggcacgggg aaagcgcggt gaacgagaag ctgaaagcgg agctgatgcg
     3961 ggaatataac agccgctatt ttaacgtgcc ggtgcctgaa ctgccggagg acaaatccgc
     4021 ccgccggtgg tggccgttcg gcaaaaaata aacgccagca ccggccatgc cggtgctgtt
     4081 attcctcccc gagcttatcc cgcatcacct gccagagtgt ttccgcatcc tcgtgcagcc
     4141 gctcgcacat gtcggccggg gtatccatat ccagctcgtt cagtttctcg agcaacagca
     4201 gcgactggtc cttaatgaat ttagccatat tgagggcagt tttttcctgt tttgtcatga
     4261 ttctttcctt ccgggcatgg tgtgcgcctg tcgggtatac tgtctcaaaa atagcggagt
     4321 gagacaatgg cgtgggtgac tgtgagacag gcgacggaac tgacggggaa agcccggagt
     4381 tccctgtatc gggatatggc gaaaggccgc gtatcatacc gtacggaagc tgatggtggt
     4441 cgggtggtgg ataccagcga gcttatccgg gtgtacggtg agttaagaca gggtgagact
     4501 cacgagcggg acgggttgag actgccggat gagactgaaa aaacggcctc cgacgcgttg
     4561 atcgcggaga taaaagcact cagggaggag gtggccggac tgcggcagga aatgcaggcc
     4621 atgagactgc tggaacacaa accggagaca gcagagacac cggccggaac accgcgccgg
     4681 tggtggcagt ggggaaaacg ctgacgcgct gtgcttgtcc aaccggcgac ggccacgcaa
     4741 tgaattgcgc ccccgtcacc ggttatcagc gaacggtatg gggattctgg cgctggccaa
     4801 ccacggccag aacccggact ttcctggtct ggtcatcaac atcatacagg acatgctgtc
     4861 ccatcagact gatccggcga acgtcctcgc catagtgtga gtccacttca tagaggcgcg
     4921 ggaagtcggc cagtttgtcc gccgcagtga gaacgcgatc ggtaacgttc tgcgcatccc
     4981 acagggatga attttccgcg atatagtcaa acagcatcgt tacatcctcg atggctccct
     5041 gtttccattc cacatcatac ggcatcgcgc agttcctgat aacggccatg caggcgctgg
     5101 cggagttgtt ccgtggtcat gcccggacgc gtgtcagcac gggcggcggt tactttggcg
     5161 cgaacctgat cttcatactc tgcctgggcc agttcttcgt tagccaggcg ttgcaacaac
     5221 gcagctttgt ccgggtcact ttccggcagt atgcggggca ggttttcagc cagttcccgc
     5281 aggaagttgg cgttttcgta gtgtgtagtg ttgctcattg cggaggctcc cggattaatg
     5341 cggtgatatg aagaagttta gcagggggcg gtctgaaaga atatggtcgt gtcagtcagg
     5401 ctgatgaagc agaaagtcgg taaaaaaagg gcttacggca tccattttac gtcaaaacat
     5461 atgctatgca gttgcgtgca taggcatgca ttaggataaa gtttaccggg cgcgtttccg
     5521 gcggttttcc gggtgatttg ttgcctgttt tatcccgtag ccgccggaaa cgctctgagg
     5581 gcctctcggg cggtgctgat aacgggtttt atggtaaatg gctggttatg aggcattcag
     5641 ctgacgattt ttgcgtcaac ttttcgctgt atgtttaaac atgagtttaa cattagcgtc
     5701 atctgatagc gctgttgcta atttcatcga cccgacaggt aatttccttg taaatcaagc
     5761 gcgaaagatc agcaaaaaag ctatgtgtgc gcttatggaa taaggtagaa taagggattc
     5821 tgatgatcgt gaggttgtca gtgaaaaacg aggcagctat cagatcttcg gcctgagaaa
     5881 ctaaggattc tgatagctgc cggtgactca gttcgtgaaa actgaatctt acctgatcaa
     5941 caaacgcccg attagggcgt ttgtcaagtg gtgctgcatt atgtagtaac ttggtaccga
     6001 cttgccaggc atttttcaca gttttttgat gtgcgaatgc tcatccggac accgtcacct
     6061 gttatttatc ctctgtaaac aggtgctata aatgcaaaaa gtaactgatc tgtatcctcc
     6121 tgaaattgct cgccataagc tccagaatca cttcgccggt aataccgtta tgctggagtt
     6181 aatccagaaa ctaaataaaa ccagcctgtg tacttttgcg gcgctctgtg acggcaacgt
     6241 agtgaccact tccggctata acatcacggc cgatctatgt gttaaccgtg cgtcagccgt
     6301 ggcccattcg cttaagcaaa aatatctgcc agttacggcc agaacgattt cgacaaaggc
     6361 tgatgtaggt ggtgcggtaa agcaggcggc tttctgtatc gatgaggacg atcttgcaag
     6421 gctgaaatca gagccggaaa agatgatgaa agagtgcgaa cgtaacctga acagccagaa
     6481 gcgcaccaat gctcagaagg aaatgagccg gttgtacaag gagtttggtg aagacggcat
     6541 actggcgctg ttacgcaatg ttgcccagtc gaacggtaca ccgccgccag gcgcacaccc
     6601 tgcaagttga taccagtaaa gcccctaagg ggctttattt ttaaggtttt ctggatgccg
     6661 ccagctcttg atctgtcagc taatcgcggt gcagatagtt cccttctacc ggcggtggcg
     6721 ttaccagttt tgcttttcct tctttcggac gagaatttca ctcttaccgt acattttcgt
     6781 acggttggac ctcgaacccc tttcaggccc atggccagtg cctgagcgac aaaggcgtcc
     6841 gccaggcgct tttcttcagg tgcgtcatgg tggcctccgg gttgtctccg attcctgaac
     6901 agtttaaccg caggtactct cctcatgcca tttcgctttc aggtacatct ataccaatat
     6961 aaaagtaagt gtgatgaatg tctcaaataa taaaatttgt tgccatgaga aattttcggg
     7021 aaaagacgcg atctgcttac aggcggctcc gggcgctttt ttgtgcctga agatgagaac
     7081 taatctcata tattgacacc tgaaaactgg aggagtaagg taacaattat actgtgtata
     7141 catacagtgt gcgccgggag accggtagag atcaaggggt gaaagtcccc gaccattgaa
     7201 ggaccagcaa tccacaaggt ccccgagtca tgcgttgcat accgcgaggt atggggcgaa
     7261 gcgttgacag gggtgttgac aggccagcca ttgagccacg aaatgtatat taaattaccg
     7321 ggtgccgacg ttgtactgtt aacggaaggc aacatcatag ggtgcgatac tgcgagtgcc
     7381 acatggaccc ggcggggtct gagaccctgg catgtcaata cgatctctac gcgggaaccg
     7441 ggagatctcc cctctgacca tctgccagtg tcggagatgg cccgcaccgg gaagacgagg
     7501 agtcatagcc ggtgatgtac ggagaggaga agtcggactc gctcatagta gcggcgaagc
     7561 aggcgaacaa cccgaaagga gcggagtcag tggagcgaag gagcggggcc aaggggaacg
     7621 cggaacagcc acacatgcgc cggacacaga gccgggaaag catgtcacag aggctgtcac
     7681 gcgtgcggga agctgcgaag cagcggaaga aagaacggtt tacagcattg ttccacctgc
     7741 tgacagtcga agcactggaa gccgcattcc tctccctgag caggaaagcg gccgccggag
     7801 tggatggcat caggtggatg gactacgccg gaaacatgaa gaacaacata acagatctgc
     7861 accggaggct acatcagggc agctacaggg cgcagcccgg caggcgtcac tacatcccaa
     7921 aagcggatgg aaaacaacgc ccgctcggca tcgcctcgct ggaggacaag atcgtccagt
     7981 atgcgctggt gaaaatcctg aacgcagtct atgaaaacga ctttatgggg ttctcatacg
     8041 ggttcagacc cgggcgaagc cagcacgatg cactggacgc actggccaca gggctggtac
     8101 gcactaacgt aaactgggta ctggatgccg acatcagtca gttctttgac agggtgagcc
     8161 acgaatggct gatcaggttc acagagcatc ggatcggcga ccggagggta atcaggctca
     8221 tacgtaagtg gctcacagcc gggacgtcgg aggagggtca atggcgagca acggaggaag
     8281 gcaccccaca gggtgcggtc atctcaccgc tgctggcaaa catatacctc cactacgtct
     8341 tcgatctgtg ggcgcatcag tggcgacgtc gctatgccac aggcaatgtg gtaatggtca
     8401 gatacgccga tgacatcgtc atcgggttcg acaaacgata cgatgcccgg cgcttccgta
     8461 tagccatgca gcgcagactg agggagttcg gactcacggt tcacccggag aaaacccgtc
     8521 tgatggagtt cggccgcttc gctgccgaaa accgtgccat caggggaaaa ggcaaaccag
     8581 aaacgttcaa cttcctcggg ttcacgcaca tcagcgggaa agatcgcaac ggcaggttca
     8641 tgctgatacg aaagacccgc cgggatcgga tgacggcaac tctgaaagcc atcaaagacg
     8701 gtctgcgaag gcgctggcat tactcaatcc ccgaacaggg aaaatggctc aggagagtgg
     8761 ttcagggata cctgaactat cactcggtac cgggcaactt ccccaccatg cagaagttca
     8821 ggacacacgt aacaaacctc tggcgccggg cgctcaggcg caggagccag aaggatgata
     8881 cgacctggac gaaagcaaac aaactggcag ccgcatggct accaagggtt cgggttcttc
     8941 atccatggcc tgtggagcgg ttcaccgcca gacacccgag gcaggagccc ggtgcgtaaa
     9001 tcgcgcacgc cgggatctgt gcggggggta tccggtaacg ggtatcccta ccgcgacata
     9061 ttggttttaa tttattgttt taaatgtcaa agaggaaaac gatatgagtg gtggagacgg
     9121 tcgaggtccg ggtaattcag gtctgggaca taatggtggt caggccagtg ggaatgtgaa
     9181 cggtacgtct ggtaaaggtg gcccttcatc aggtggtggt acggatccaa acagcgggcc
     9241 gggctggggt acgacgcata cgccgaatgg agatattcat aactataatc cgggggagtt
     9301 tggtaacggc gggagtaaac ccggtggtaa tggtggtaac agcggcaatc atagcggtag
     9361 ctctggtggc ggacagtctt cggccactgc gatggccttc ggtctgcctg ccctggctac
     9421 tccgggggct gaaggactgg ctttatcagt ttccggcgat gcgttgtcgg ccgccgttgc
     9481 tgatgtgctg gctgccctga aggggccgtt taagtttggt ctgtggggga ttgcgatcta
     9541 cggtgtgctg ccttctgaga ttgcaaaaga tgatccgaaa atgatgtcaa aaattatgac
     9601 gtcattaccg gccgatgcgg tgacggagac tccggcaagt actttaccac tggaccaggc
     9661 gacggttcgt gtcagacaac gggttgtgga tgtggtgaag gatgagcggc agcatattgc
     9721 ggttgtcgca ggtcggccaa tgagtgtccc tgtggtggat gcgaaaccga caaaacgtcc
     9781 gggggtattc agtgtgtcga ttccgggtct cccgtctctg caggtgaacg taccgaaagg
     9841 tgttccgaca gcgaaagccc cgccaaaagg cattgttgct gaaaaaggtg attcacgtcc
     9901 ggctggtttt acagccggtg gtaactcccg tgaggccgtt attcgtttcc cgaaagagac
     9961 cggacagaag ccggtttatg tgtcggtgac agatgttctt accccggcac aggtaaaaca
    10021 gcgtcaggag gaagaaaagc gtcgccagca ggcatgggac gccgctcatc cggaagaggg
    10081 gctgaaaaga gactatgata aagcgaaagc tgagctggat gccgaagata aaaatattgc
    10141 gaccttaaac agccgcattg catcgacaga gaaggcgctc cccggtgcaa gggctgctgt
    10201 tcaggaagcc gataaaaagg taaaagaggc agaggcaaat aaagatgatt ttgtgactta
    10261 taacccgcct catgaatatg gctccgggtg gcaggatcag gttcgctatc ttgataagga
    10321 tattcagaat cagaatgaga aattaaaagc ggctcaggca tctttaaacg caatgaatga
    10381 atccttatcc agagataagg ctgcacttac cggggcgatg gagagccgga aacaaaagga
    10441 gaaaaaagcg aaggatgcag aaaataagtt aaatgaggaa aagaacaagc ctcgcaaggg
    10501 agttaaagat tacggtcatg attatcatcc cgctccgaag accgaagaaa tcaaggggtt
    10561 gggggaatta aaaaaagcac ctaaaaaaac acctaaacag ggtggtggtg gtagacgtga
    10621 ccgttggatt ggtgataaag gccgtaagat ttatgaatgg gactcccagc acggtgagct
    10681 tgaagggtat cgtgccagtg atggcgaaca cctcggggca tttgatccaa aaacgggtaa
    10741 gcaaattaaa ggtccggatc cgaaaggacg aaacattaaa aaatatcttt gagaggtaag
    10801 tatggggctt aaattaaatt taacctggtt tgataagaag actgaggaat ttattggtga
    10861 ggagtattct aaagactttg gtgatgatgg ttctgtcatt gaaagccttg gaatgccttt
    10921 aaaggataat attaacaatg gcgggtttga tgttgagaaa tcatgggttc cgttgttgca
    10981 gccatatttt aaaaataaaa ttgaagtcga taagtactgg tatcaaattt catttgatta
    11041 tcgggacggt aactggtaac aaaaaattat caaggatgat ttgaaataca gacttccggt
    11101 gttcagggat gaatgccggg gtttttaaat acagggaagg tatatgaaaa aggtaaaggt
    11161 tgtttttctt tttatattga tttttttagg ctttcttctg gtcgcatgtc aggcaaacta
    11221 tatccgggat gttcagggtg gaacggtggc accatcgtcc tcctctgaac tgacggggat
    11281 cgcggttcag tagaaaagat caaaggatct tcttgagatc ctttttttct gcgcgtaatc
    11341 ttttgccctg taaacgaaaa aaccacctgg ggaggtggtt tgatcgaagg ttaagtcagt
    11401 tggggaactg cttaaccgtg gtaactggct ttcgcagagc acagcaacca aatctgtcct
    11461 tccagtgtag ccggactttg gcgcacactt caagagcaac cgcgtgttta gctaaacaaa
    11521 tcctctgcga actcccagtt accaatggct gctgccagtg gcgttttgcg tgcttttccg
    11581 ggttggactc aagtgaacag ttaccggata aggcgcagca gtcgggctga acggggagtt
    11641 cttgcttaca gcccagcttg gagcgaacga cctacaccga gccgagatac cagtgtgtga
    11701 gctatgagaa agcgccacac ttcccgcaag ggagaaaggc ggacaggtat ccggtaaacg
    11761 gcagggtcgg aacaggagag cgcaagaggg agcgacctac cggaaacggt ggggatcttt
    11821 aagtcctgtc gggtttcgcc cgtactgtca gattcatggt tgagcctcac ggctcccaca
    11881 gatgcaccga aaaagcgtct gtttatgtga actctggcag gagggcggag cctatggaaa
    11941 aacgccaccg gcgcg
//
