LOCUS       OW967554               13636 bp    DNA     circular BCT 22-MAY-2022
DEFINITION  Klebsiella pneumoniae isolate 512 genome assembly, plasmid: P2.
ACCESSION   OW967554
VERSION     OW967554.1
DBLINK      BioProject: PRJEB42440
            BioSample: SAMEA8065859
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Alioto,T., Alioto,T. and Gomez Garrido,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2022) CNAG-CRG, CNAG, Spain
FEATURES             Location/Qualifiers
     source          1..13636
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /isolate="512"
                     /isolation_source="Hospital Reina Sofia (Cordoba)"
                     /db_xref="taxon:573"
                     /plasmid="P2"
     gene            complement(1946..2074)
                     /locus_tag="AI2817V1_5181"
     mRNA            complement(1946..2074)
                     /locus_tag="AI2817V1_5181"
                     /note="AI2817v1_5181.mrna"
     CDS             complement(1946..2074)
                     /locus_tag="AI2817V1_5181"
                     /note="long variant; AI2817v1_5181.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5489330.1"
                     /translation="MEKRHLRGLAVLPHMLVPCLFTESVGNFACVRSARRSLTAGA"
                     /name="hypothetical protein"
     exon            complement(1946..2074)
                     /locus_tag="AI2817V1_5181"
                     /note="AI2817v1_5181.mrna"
                     /number=1
     gene            complement(2949..3206)
                     /locus_tag="AI2817V1_5182"
     mRNA            complement(2949..3206)
                     /locus_tag="AI2817V1_5182"
                     /note="AI2817v1_5182.mrna"
     CDS             complement(2949..3206)
                     /locus_tag="AI2817V1_5182"
                     /note="long variant; AI2817v1_5182.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Colicin-E3 immunity protein"
                     /protein_id="CAH5489446.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="Colicin-E3 immunity protein"
     exon            complement(2949..3206)
                     /locus_tag="AI2817V1_5182"
                     /note="AI2817v1_5182.mrna"
                     /number=1
     gene            complement(3216..>3752)
                     /locus_tag="AI2817V1_5183"
     mRNA            complement(3216..3752)
                     /locus_tag="AI2817V1_5183"
                     /note="AI2817v1_5183.mrna"
     CDS             complement(3216..>3752)
                     /locus_tag="AI2817V1_5183"
                     /note="short variant; AI2817v1_5183.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Colicin-E3"
                     /protein_id="CAH5489575.1"
                     /translation="VTYNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQTSLNEMNESL
                     SRDKAALSGAMESRKQKEKKAKDAENKLNEEKKKPRKGTKDYGHDYFPDPKTEDIKGLG
                     ELKEGKPKTPKQGGGGKRARWYGDKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGK
                     QVKGPDPKRNIKKYL"
                     /name="Colicin-E3"
     exon            complement(3216..3752)
                     /locus_tag="AI2817V1_5183"
                     /note="AI2817v1_5183.mrna"
                     /number=1
     gene            complement(4173..4877)
                     /locus_tag="AI2817V1_5184"
     mRNA            complement(4173..4877)
                     /locus_tag="AI2817V1_5184"
                     /note="AI2817v1_5184.mrna"
     CDS             complement(4173..4877)
                     /locus_tag="AI2817V1_5184"
                     /note="long variant; AI2817v1_5184.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5489695.1"
                     /translation="MNPFKGRHFQRDIIRWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="hypothetical protein"
     exon            complement(4173..4877)
                     /locus_tag="AI2817V1_5184"
                     /note="AI2817v1_5184.mrna"
                     /number=1
     gene            complement(4889..>5146)
                     /locus_tag="AI2817V1_5185"
     mRNA            complement(4889..5146)
                     /locus_tag="AI2817V1_5185"
                     /note="AI2817v1_5185.mrna"
     CDS             complement(4889..>5146)
                     /locus_tag="AI2817V1_5185"
                     /note="short variant; AI2817v1_5185.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Streptomycin 3''-adenylyltransferase"
                     /protein_id="CAH5489817.1"
                     /translation="VIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDID
                     LLVTVTVRLDETTRRALINDLLETALLQIVGGDKLIIPFC"
                     /name="Streptomycin 3''-adenylyltransferase"
     exon            complement(4889..5146)
                     /locus_tag="AI2817V1_5185"
                     /note="AI2817v1_5185.mrna"
                     /number=1
     gene            complement(5228..5833)
                     /locus_tag="AI2817V1_5186"
     mRNA            complement(5228..5833)
                     /locus_tag="AI2817V1_5186"
                     /note="AI2817v1_5186.mrna"
     CDS             complement(5228..5833)
                     /locus_tag="AI2817V1_5186"
                     /note="long variant; AI2817v1_5186.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Aminoglycoside N(6')-acetyltransferase type 1"
                     /protein_id="CAH5489906.1"
                     /translation="MSIQHFQTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRS
                     HIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGW
                     WEEETDPGVRGIDQLLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAI
                     RCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA"
                     /name="Aminoglycoside N(6')-acetyltransferase type 1"
     exon            complement(5228..5833)
                     /locus_tag="AI2817V1_5186"
                     /note="AI2817v1_5186.mrna"
                     /number=1
     gene            complement(6016..6573)
                     /locus_tag="AI2817V1_5187"
     mRNA            complement(6016..6573)
                     /locus_tag="AI2817V1_5187"
                     /note="AI2817v1_5187.mrna"
     CDS             complement(6016..6573)
                     /locus_tag="AI2817V1_5187"
                     /note="long variant; AI2817v1_5187.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Transposon Tn3 resolvase"
                     /protein_id="CAH5490025.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="Transposon Tn3 resolvase"
     exon            complement(6016..6573)
                     /locus_tag="AI2817V1_5187"
                     /note="AI2817v1_5187.mrna"
                     /number=1
     gene            6735..9740
                     /locus_tag="AI2817V1_5188"
     mRNA            6735..9740
                     /locus_tag="AI2817V1_5188"
                     /note="AI2817v1_5188.mrna"
     CDS             6735..9740
                     /locus_tag="AI2817V1_5188"
                     /note="long variant; AI2817v1_5188.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5490141.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="hypothetical protein"
     exon            6735..9740
                     /locus_tag="AI2817V1_5188"
                     /note="AI2817v1_5188.mrna"
                     /number=1
     gene            <9733..10065
                     /locus_tag="AI2817V1_5189"
     mRNA            9733..10065
                     /locus_tag="AI2817V1_5189"
                     /note="AI2817v1_5189.mrna"
     CDS             <9733..10065
                     /locus_tag="AI2817V1_5189"
                     /note="short variant; AI2817v1_5189.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5490260.1"
                     /translation="LLNVSFRSTERQTPFDPNFSTQKADTTRMMVPFFRQFWDMGAKDK
                     ATGKSRSDVQQRIQQFHSQEFLNSLQGTTQFAGTDYRSKDLTPKKSRLLADTISAVYLD
                     GYEGRQ"
                     /name="hypothetical protein"
     exon            9733..10065
                     /locus_tag="AI2817V1_5189"
                     /note="AI2817v1_5189.mrna"
                     /number=1
     gene            10371..10634
                     /locus_tag="AI2817V1_5190"
     mRNA            10371..10634
                     /locus_tag="AI2817V1_5190"
                     /note="AI2817v1_5190.mrna"
     CDS             10371..10634
                     /locus_tag="AI2817V1_5190"
                     /note="long variant; AI2817v1_5190.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5490355.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     exon            10371..10634
                     /locus_tag="AI2817V1_5190"
                     /note="AI2817v1_5190.mrna"
                     /number=1
     gene            10624..10923
                     /locus_tag="AI2817V1_5191"
     mRNA            10624..10923
                     /locus_tag="AI2817V1_5191"
                     /note="AI2817v1_5191.mrna"
     CDS             10624..10923
                     /locus_tag="AI2817V1_5191"
                     /note="long variant; AI2817v1_5191.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5490472.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="hypothetical protein"
     exon            10624..10923
                     /locus_tag="AI2817V1_5191"
                     /note="AI2817v1_5191.mrna"
                     /number=1
     gene            complement(10985..11362)
                     /locus_tag="AI2817V1_5192"
     mRNA            complement(10985..11362)
                     /locus_tag="AI2817V1_5192"
                     /note="AI2817v1_5192.mrna"
     CDS             complement(10985..11362)
                     /locus_tag="AI2817V1_5192"
                     /note="long variant; AI2817v1_5192.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5490586.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     exon            complement(10985..11362)
                     /locus_tag="AI2817V1_5192"
                     /note="AI2817v1_5192.mrna"
                     /number=1
     gene            11431..11610
                     /locus_tag="AI2817V1_5193"
     mRNA            11431..11610
                     /locus_tag="AI2817V1_5193"
                     /note="AI2817v1_5193.mrna"
     CDS             11431..11610
                     /locus_tag="AI2817V1_5193"
                     /note="long variant; AI2817v1_5193.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Regulatory protein rop"
                     /protein_id="CAH5490702.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Regulatory protein rop"
     exon            11431..11610
                     /locus_tag="AI2817V1_5193"
                     /note="AI2817v1_5193.mrna"
                     /number=1
     gene            complement(11638..12168)
                     /locus_tag="AI2817V1_5194"
     mRNA            complement(11638..12168)
                     /locus_tag="AI2817V1_5194"
                     /note="AI2817v1_5194.mrna"
     CDS             complement(11638..12168)
                     /locus_tag="AI2817V1_5194"
                     /note="long variant; AI2817v1_5194.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5490818.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     exon            complement(11638..12168)
                     /locus_tag="AI2817V1_5194"
                     /note="AI2817v1_5194.mrna"
                     /number=1
     gene            complement(12175..12906)
                     /locus_tag="AI2817V1_5195"
     mRNA            complement(12175..12906)
                     /locus_tag="AI2817V1_5195"
                     /note="AI2817v1_5195.mrna"
     CDS             complement(12175..12906)
                     /locus_tag="AI2817V1_5195"
                     /note="long variant; AI2817v1_5195.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5490940.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="hypothetical protein"
     exon            complement(12175..12906)
                     /locus_tag="AI2817V1_5195"
                     /note="AI2817v1_5195.mrna"
                     /number=1
     gene            complement(12906..>13619)
                     /locus_tag="AI2817V1_5196"
     mRNA            complement(12906..13619)
                     /locus_tag="AI2817V1_5196"
                     /note="AI2817v1_5196.mrna"
     CDS             complement(12906..>13619)
                     /locus_tag="AI2817V1_5196"
                     /note="short variant; AI2817v1_5196.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH5491053.1"
                     /translation="VAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARDEFRE
                     WPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFVKTTV
                     LDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQKEARP
                     LFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEFRPPA
                     DGGGPKADDDFAGIY"
                     /name="hypothetical protein"
     exon            complement(12906..13619)
                     /locus_tag="AI2817V1_5196"
                     /note="AI2817v1_5196.mrna"
                     /number=1
     ARG             complement(5232..5782)
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(4890..5146)
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             complement(5229..5833)
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          2034..2612
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(12179..12906)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.34e-150"
ORIGIN
        1 tctgcaggac gctcaggtca gcgacgtttt ccagcctagt gatcaacccc ttcacgtcct
       61 ttttcagggc ctccggcagc gcgtacgccg ccgccagcac ctgctgaatg tttgccccct
      121 gcggaaactg ctccgcaatc agcttcgccg ctttctgctc gctgatgcgg tagtggtccg
      181 ccacgtcgcc ggtctcgccc aggttaagcc cggcaatcag caggtttttc agcgcgtact
      241 ggtcgagatc gcggaacaga ttcagctgcg ccggtttccc cggccgcaga tccagcaggg
      301 tgaagtccgg acagtgcgcc cggaagacgt gcggcgccca tgcgtcccct ttggggtcga
      361 agtacaccac cgcgtccccg aaatcgcgta cgcagcgaat gagcgcgttg gtggccatca
      421 cgctcttgcc gctcccgggc aggccgagga tctgaatgtt ggtcttgcgc caggtatcac
      481 gcggaaccag caccggcttg ccctgctcat ccttacccag aaacaccgcc tgctcctgcc
      541 gggcctgctc cgaggaaaaa tcggccagcg cattaaccgg taccggctcc ccgaaatgca
      601 ggtggcgcac gtcggtcatc tctcctgtcc gctggctgct gcgccggctc tcctgattca
      661 gtttcgcgtt caccgcctcg tcagcagccg caaaatgacc gtcaagcagc aggaacgcca
      721 gcagccgcgc caacacaatc ccgacagcca gcccgcccgc gcaccaggca atcccgaaca
      781 ggttagccgg ctgcagcagg taataatctg cgtttgcgta gaggtccgga cgcaggacgg
      841 tttctcccca gctctcgata aacacggcga caaccagccc ccccagaagg gccagaccgg
      901 ccgcgccggt cagccagtac gcgtagttcc agacatgtcg acgtgccctg accatccgcc
      961 cgggcgaatc cagcgaggcc agcaccgaaa atggcgctgg ccgtttatta tcgcgcttat
     1021 agcgatcggc atactcccgt cgctccttat gactcagccc cacaaaacgc atccgtccgg
     1081 cccaaagttc agccagaccg aaaaacaggc cgataactag gaaagccccg gccagaccgt
     1141 aatactcctg gtacagccag ctgacccacg gataaatctg ccgggccagc tccggaatgt
     1201 gccacttcca ggcaagcgaa tccgtattaa acatgttctc tctccttcag acgatggttt
     1261 gccggcgtga tgtgcagccc ccgctgcaca agccgcggac atgccccaag gcatggcggc
     1321 ggcggtcacg tccgtggtga ttgcgttcag ctttcaccac ggaggccagc ctctttccgc
     1381 cccatgcgga aaaggcgcag ccccggagga acaacgagca cgccccagcg tgtgagagga
     1441 aaaggcggca ccccagtgcg gtcttttccg gtgttccggc ccccgtcaga gttcgccata
     1501 gcgagcggct gaccacccgc aaaatcagga gcagctttgc tgcttcgcca ggtgcgtcca
     1561 gcaccgtgga tttttgtggg tggtcaggcg tgagcctgac gggggccggg tgaatttctg
     1621 gcgtggccgg cgtccagccg gacggagcca gaaagagggg gagagaccgt gcgtcggtgg
     1681 cgtccagcca gcgtaagcag gggatatccc cctgaggtca gccacgccct cgcggggatg
     1741 acctgtattt ctccgtaagg agaaaaaagc aacagagata ggttaacgta aaatgttcag
     1801 cgaaaaaccg atatgattca cctatcctgg taatttatta tcagggaata taaagactta
     1861 atcaggggac aatatgccac atcagcgcgt ccggtgtccg tcttgtaggt gccggggaaa
     1921 ttgcgcctcc tcgctcactc ggtcgctacg ctccggccgt gagactgcgg cgggcgctgc
     1981 ggacacatgc aaagttaccc acagattccg tgaataagca ggggactaac atgtgaggca
     2041 aaacggcaag gccacgcagg tggcgttttt ccataggctc cgccctcctg actgagttca
     2101 cataaacaga cgctttttcg gtgcatctgt gggagccggt ggctcaacca tgaatcagtc
     2161 aggagtggcg aaacccgaca ggacttaaag atcatcaccg tttccgatga atcgctccct
     2221 cttgcgctct cctgttccaa ccctgccgtt tcccggatac ctgttccgcc tttctccctt
     2281 gcgggaagtg tggcgctttc tcatagctca cactctggta tctcggctcg gtgtaggtcg
     2341 ttcgctccaa gctgggctgt aagcaagaac cccccgttca gcccgactgc tgcgccttat
     2401 ccggtaactg ttcacttgag tccaacccgg aaaagcacgc aaaacgccac tggcagcagc
     2461 cattggtaac tgggagttcg cagaggattt gtttagctaa acacgcggtt gctcttgaag
     2521 tgtgcgccaa agtccggcta cactggaagg acagatttgg ttgctgtgct ctgcgaaagc
     2581 cagttaccac ggttaagcag ttccccaact gacttaacct tcgatcaaac cacctcccca
     2641 ggtggttttt tcgtttacag ggcaaaagat tacgcgcaga aaaaaaggat ctcaagaaga
     2701 tcctttgatc ttttctactg aaccgcgatc cccgtcagtt cagaggagga cgatggtgcc
     2761 accgttccac cctgaacatc ccggatatag tttgcctgac atgcgaccag aagaaagcct
     2821 gaaaaaatca atataaaaag aaaaacaacc tttacctttt tcatatacct tccctgtatt
     2881 taaaaacccc ggtattcatc cctgaacacc ggaagtctgt atttcaaatc atccttgata
     2941 acttttgctt accagttacc atcccggtaa acaaaggata caaagtaatc aaatttacta
     3001 atatcgatta catttttaaa gtgtggctgt aatatcgaaa cccatgattt ttcaacatca
     3061 aaccaaccat tattaatatt atcctttaaa ggcatcccca gactttcaat gacagaacca
     3121 tcatcaccga agtcttttga gtattcacca cctttaaact cttcggtttt cttatcaaac
     3181 caatgaatat gtaatttaag ccccatattt acctcttaaa gatatttttt aatgtttcgt
     3241 tttggatccg gccctttaac ctgcttaccc gtttttggat cgaatgcccc gaggtgttcg
     3301 ccatcactgg cgcggtaccc ttcaagctca ccgtgctggg aatcccattc ataaatttta
     3361 cgctttttat caccatacca tcgggcccgc ttaccaccac caccttgttt aggggtttta
     3421 ggtttaccct ctttcaactc tcccaacccc ttaatatctt cagtcttggg atcaggaaaa
     3481 taatcatggc cgtaatcttt agttccctta cgaggttttt tcttttcctc atttaattta
     3541 ttttctgcat ccttcgcttt tttctccttt tgtttccggc tctccatcgc cccggaaagc
     3601 gcagccttat ccctggataa ggattcattc atttcgttta aagatgtctg ggcagctttt
     3661 aatttctcat tctgattctg aatatcctta tcaagatagc gaacctgatc ctgccacccg
     3721 gagccatatt catgaggcgg gttataagtc acaaaatcat ctttatttgc ctctgcctct
     3781 tttacctttt tatcggcttc ggggtctgac gctcagtgga acgaaaactc acgttaaggg
     3841 attttggtca tgagattatc aaaaaggatc ttcacctaga tccttttaaa ttaaaaatga
     3901 agttttaaat caatctaaag tatatatgag taaacttggt ctgacagtta ccaatgctta
     3961 atcagtgagg cacctatctc agcgatctgt ctatttcgtt catccatagt tgcctgactc
     4021 cccgtcgtgt agataactac gatacgggag ggcttaccat ctggccccag tgctgcaatg
     4081 ataccgcgag acccacgctc accggctcca gatttatcag ggcactgttg caaagttagc
     4141 gatgaggcag ccttttgtct tattcaaagg ccttacattt caaaaactct gcttaccagg
     4201 cgcatttcgc ccaggggatc accataataa aatgctgagg cctggccttt gcgtagtgca
     4261 cgcatcacct caataccttt gatggtggcg taagccgtct tcatggattt aaatcccagc
     4321 gtggcgccga ttatccgttt cagtttgcca tgatcgcatt caatcacgtt gttccggtac
     4381 ttaatctgtc ggtgttcaac gtcagacggg caccggcctt cgcgtttgag cagagcaagc
     4441 gcgcgaccat aggcgggcgc tttatccgtg ttgatgaatc gcgggatctg ccacttcttc
     4501 acgttgttga ggattttacc cagaaaccgg tatgcagctt tgctgttacg acgggaggag
     4561 agataaaaat cgacagtgcg gccccggctg tcgacggccc ggtacagata cgcccagcgg
     4621 ccattgacct tcacgtaggt ttcatccatg tgccacgggc aaagatcgga agggttacgc
     4681 cagtaccagc gcagccgttt ttccatttca ggcgcataac gctgaaccca gcggtaaatc
     4741 gtggagtgat cgacattcac tccgcgttca gccagcatct cctgcagctc acggtaactg
     4801 atgccgtatt tgcagtacca gcgtacggcc caccgaatga tgtcacgctg aaaatgccgg
     4861 cctttgaatg ggttcatgtg cagctccatc agcaaaaggg gatgataagt ttatcaccac
     4921 cgactatttg caacagtgcc gtttccaaaa ggtcgttgat caaagctcgc cgcgttgttt
     4981 catcaagcct tacggtcacc gtaaccagca aatcaatatc actgtgtggc ttcaggccgc
     5041 catccactgc ggagccgtac aaatgtacgg ccagcaacgt cggttcgaga tggcgctcga
     5101 tgacgccaac tacctctgat agttgagtcg atacttcggc gatcaccgct tccctcatga
     5161 tgtttaacgt ttgacatgag gggcggccaa gggcgccagc ccttggacgt ccccctcgat
     5221 ggaagggtta ggcaacactg cgtgttcgct cgaatgcctg gcgtgtttga accatgtaca
     5281 cggctggacc atctggggtg gttacggtac cttgcctctc aaaccccgct ttctcgtagc
     5341 atcggatcgc tcgcaagttg ctcggcgacg ggtccgtttg gatcttggtg acctcgggat
     5401 cattgaacag caactcaacc agagctcgaa ccagcttggt tcccaagcct ttgcccagtt
     5461 gtgatgcatt cgccagtaac tggtctattc cgcgtactcc tggatcggtt tcttcttccc
     5521 accatccgtc cccgcttcca agagcaacgt acgactgggc atacccaatc ggctctccat
     5581 tcagcattgc aatgtatgga gtgacggact cttgcgctaa aacgcttggc aagtactgtt
     5641 cctgtacgtc agcaagtgtc gggcgtgctt cttctccgcc ccaccactcg acgatatgag
     5701 atcgatttag ccactcatag agcatcgcaa ggtcatgctc agtcatgagg cgcagtgtga
     5761 cggaatcgtt gctgttggtc acgatgctgt actttgtgat gcctaacttt gtttggaaat
     5821 gttgaatact catactcttc ctttttcaat attattgaag catttatcag ggttattgtc
     5881 tcatgagcgg atacatattt gaatgtattt agaaaaataa acaaataggg gttccgcgca
     5941 cttttccccg aaaagtgcca cctgacgtct aagaaaccat tattatcatg acattaacct
     6001 ataaaaatag gcgtatcacg aggccctttc gtcttcaaga attttataaa ccgtggagcg
     6061 ggcaatactg agctgatgag caatttccgt tgcaccagtg cccttctgat gaagcgtcag
     6121 cacgacgttc ctgtccacgg tacgcctgcg gccaaatttg attcctttca gctttgcttc
     6181 ctgtcggccc tcattcgtgc gctctaggat cctccggcgt tcagcctgtg ccacagccga
     6241 caggatggtg accaccattt gccccatatc accgtcggta ctgatcccgt cgtcaataaa
     6301 ccgaaccgct acaccctgag catcaaactc ttttatcagt tggatcatgt cggcggtgtc
     6361 gcggccaaga cggtcgagct tcttcaccag aatgacatca ccttcctcca ccttcatcct
     6421 cagcaaatcc agcccttccc gatctgttga actgccggat gccttgtcgg taaagatgcg
     6481 gttagctttt acccctgcat ctttgagcgc tctgatctga atatcgaggg actgctggct
     6541 ggttgagacc cgcgcataac caaaaattcg cataaaaatg taccttaaat cgaatatcag
     6601 acacgatgtg tctattatgc caaaatgacg atttaatgga cactcaaacg aagccgtttt
     6661 actatgtctg ataatttata atatttcgaa cggttgcagt tgtgttaaaa aagccgtcag
     6721 gcagggaggc cgatatgccc gttgattttt tgaccactga gcaggttgag agttatggca
     6781 ggttcactgg cgaacccgat gaacttcagc tggcgcgtta ttttcatctt gatgaagcgg
     6841 ataaagaatt tatcgggaaa agccggggtg atcacaatcg acttggtatt gccctgcaaa
     6901 tcgggtgtgt gcgttttctg ggcacttttc ttactgacat gaatcatatt ccttccggcg
     6961 tccggcattt taccgccaga cagctcggga ttcgtgatat caccgttctt gcagaatacg
     7021 gtcagaggga aaatacccgc cgtgagcatg cagcgctgat acgtcagcac tatcagtatc
     7081 gtgaatttgc ctggccctgg acatttcgcc ttacccgtct tttatatacc cggagctgga
     7141 taagcaacga acgtcctggc ctgcttttcg acctggcgac agggtggctt atgcaacatc
     7201 gtattattct ccccggagcc accacgctga cccggttgat ttcagaggta agggaaaagg
     7261 cgacgttgcg cctgtggaac aaactggcac tgataccgtc agccgaacag cgttcacagc
     7321 tggagatgct gctggggcca actgattgca gccgcctgtc tttactggaa tcactgaaaa
     7381 aaggccctgt gaccatcagt ggtccggcgt ttaatgaagc aattgaacgc tggaaaactc
     7441 tgaacgattt tggcctgcat gctgaaaacc tgagtacact cccggctgtg cgcctgaaaa
     7501 atctcgcacg ttatgctggt atgacttcgg tgttcaatat tgccaggatg tcaccgcaga
     7561 aaaggatggc ggttctggtt gcctttgtcc ttgcatggga aacgctggcg ctggatgatg
     7621 cactggacgt tctggacgcc atgctggccg ttatcatccg tgacgccaga aagattgggc
     7681 agaaaaaacg gctccgctcg ctgaaggatc tggataaatc tgcattggcg ctcgccagcg
     7741 catgttcgta cttgctgaaa gaagaaacac cggacgaatc gattcgtgct gaggtgttca
     7801 gctacatccc taggcaaaag ctggctgaaa tcatcacgct tgtccgtgaa attgcccggc
     7861 cctcagacga taattttcat gacgaaatgg tggagcagta cgggcgcgtt cgtcgtttcc
     7921 tgccccatct gctgaatacc gttaaatttt catccgcacc tgccggggtt accactctga
     7981 atgcctgtga ctacctcagc cgggagttca gctcacggcg gcagtttttt gacgacgcac
     8041 caacggaaat catcagtcag tcatggaaac ggctggtgat taacaaggaa aaacatatca
     8101 cccgaagggg atacacgctc tgctttctca gtaaactgca ggatagtctg agacggaggg
     8161 atgtctacgt taccggcagt aaccggtggg gagatcctcg tgcaagatta ctacagggtg
     8221 ctgactggca ggcaaatcgg attaaggttt atcgttcttt ggggcacccg acagacccgc
     8281 aggaagcaat aaaatctctg ggccatcagc ttgatagtcg ttacagacag gttgctgcac
     8341 gtcttggcga aaatgaggct gtcgaactcg atgtttctgg cccgaagccc cggttgacaa
     8401 tttctcccct cgccagtctt gatgagccgg acagtctgaa acgactgagc aaaatgatca
     8461 gtgatctgct ccctccggtg gatttaacgg agttgctgct cgaaattaac gcccataccg
     8521 gatttgctga tgagtttttc catgccagtg aagccagtgc cagagttgat gatctgcccg
     8581 tcagcatcag cgccgtgctg atggctgaag cctgcaatat cggtctggaa ccactgatca
     8641 gatcaaatgt tcctgcactg acccgacacc ggctgaactg gacaaaagcg aactatctgc
     8701 gggctgaaac tatcaccagc gctaatgcca gactggttga ttttcaggca acgctgccac
     8761 tggcacagat atggggtgga ggagaagtgg catctgcaga tggaatgcgc tttgttacgc
     8821 cagtcagaac aatcaatgcc ggaccgaacc gcaaatactt tggtaataac agagggatca
     8881 cctggtacaa ctttgtgtcc gatcagtatt ccggctttca tggcatcgtt ataccgggga
     8941 cgctgaggga ctctatcttt gtgctggaag gccttctgga acaggagacc gggctgaatc
     9001 caaccgaaat tatgaccgat acggcaggtg ccagcgatct tgtctttggc cttttctggc
     9061 tgctgggata ccagttttct ccacgcctgg ctgatgccgg tgcttcggtt ttctggcgaa
     9121 tggaccatga tgccgactat ggcgtgctga atgatattgc cagagggcaa tcagatcccc
     9181 gaaaaatagt ccttcagtgg gacgaaatga tccggaccgc aggctccctg aagctgggca
     9241 aagtacaggc ctcagtgctg gtccgttcat tgctgaaaag tgaacgtccc tccggactga
     9301 ctcaggcaat cattgaagtg gggcgcatca acaaaacgct gtatctgctt aattatattg
     9361 atgatgaaga ttaccgccgg cgcattctga cccagcttaa tcggggagaa agccgtcatg
     9421 cagttgccag agccatctgt cacggtcaaa aaggtgagat aagaaaacga tataccgacg
     9481 gtcaggaaga tcagttggga gctctggggc tggtcactaa cgccgtcgtg ttatggaaca
     9541 ctatttatat gcaggcagct ctggatcatc tccgggcgca gggtgaaaca ctgaatgatg
     9601 aagatatcgc acgcctctcc ccgctttgcc acggacatat caatatgctc ggccattatt
     9661 ccttcacgct ggcagaactg gtgaccaaag gtcatctgag accattaaaa gaggcgtcag
     9721 aggcagaaaa cgttgcttaa cgtgagtttt cgttccactg agcgtcagac cccttttgat
     9781 cccaattttt ccacccagaa agctgacaca acacgaatga tggtgccttt tttccggcag
     9841 ttctgggata tgggcgcaaa ggataaagcg accggaaaat cacggagtga tgtgcagcaa
     9901 cgcattcagc agtttcacag tcaggaattt ttaaactcac tccaaggcac aacacaattt
     9961 gcgggtaccg attaccgcag caaagacctc acaccgaaaa aatcaaggct actggctgac
    10021 accatttcag ctgtttatct cgatggctat gaaggcagac agtaagtgga tttaccataa
    10081 cgcgtcatta cgcgcaccgc tcagacgggc tcagggcgtt tccggcggct acgggataaa
    10141 acaggcaaca acccccccgg aaaactgccg gaaacgcgcc cgataaattt tatcctaatg
    10201 catgcctatg cacgcaactg catggcatat gttttgacgt aaaatggatg ccgtaagccc
    10261 ttttttaccg actttctgct tcatcagcct gactgacacg accatattct ttcagaccgc
    10321 cccctgctaa acttccttca tattgccgca ttaacccggg aggctccgca atgagcaaca
    10381 ctacacacta cgaaaacgcc aactttcttc gggaactggc tgaaagcctg ccccgcatac
    10441 tgccggaagg tggcccggac aaagctgcgc tgttgcagcg actggctaac gaagaactgg
    10501 cccaggcaga gtatgaagat caggttcgcg ccaaagtgac cgccgcccgt gctgacacgc
    10561 gtccgggtat gaccacggaa caactccgcc agcgcctgca tggccgttat caggaactgc
    10621 gcgatgccgt atgacgtgga atggaagcag ggagccatcg aggatgtaac gacgctgttt
    10681 gactatatcg cggaaaattc atccctgtgg gatgcgcaga acgttaccga ccgggttctc
    10741 gctgcggcgg acaaactggc cgacttcccg cgactctatg aagtggactc acgctatggc
    10801 gaggacgttc gccggatcag tctgatggga cagcatgtcc tctatgatgt tgatgaccag
    10861 accagaaaag tccgggttct ggccgtggtc ggccagcgcc agaatcccca tattgttctc
    10921 taataaccgg tgacggggac gcaattcatt gcgtggccgt cgccggttgg acaagcacag
    10981 cgcgtcagcg ttttccccac ggccaccacc ggcgcggtgt tccggccggg gtctctgctg
    11041 tctccggttt gtgttccagc agtctcatgg actgcatttc ctgccgtagc ccggccacct
    11101 cctccctgag tgcttttatc tccgcgatca acgcgtcgga ggccattttt tcagtctcac
    11161 ccgacagtct caactcgtcc cgctcgtgag tctcatcctg tcttaactca ccgtacaccc
    11221 ggataagctc gctggtatcc accacccggc cgccatcagc ttccgtacgg tatgatacgc
    11281 ggcctttcgc catatcccga tacagggaac ttcgggcttt acccgtcagt tccgtcgcct
    11341 gtctcaccgt cacccacgcc attgtctcac cccgctattt ttgagacagt atacctgaca
    11401 ggcgcacacc atgcccggaa ggaaagaatc atgacaaaac aggaaaaaac agccctcaat
    11461 atggctaaat ttattaagga gcagtcgctg ctattgctcg ataaactgaa tgagctggat
    11521 atggataccc cggccgacat gtgcgagcgg ctacacgagg atgcggaaac actctggcag
    11581 gtgatgcggg ataagctcgg ggaggaataa cagcaccggc atggccggtg ctggcattta
    11641 ttttttgccg aacggccacc accggcgggc aggtttgtcc tccggcagtt caggtaccgg
    11701 cacgttaaaa tagcggctgt tatattcccg catcagctcc gctttcagct tctcgttcac
    11761 cgcgctttcc ccgtgccgct cactcaccac gtcaatcatc gcgttaatct gctccggtga
    11821 gcacttcccg gcatcaacca cctgcacacc gttctcgatg gcgaaccgct ccaccttgcg
    11881 atagaggtaa tcacacagct tcattcctgt gggtttgttc cgttcccatt gcggattttt
    11941 accagtgaaa aagtacgtgg ctttttcgtc gctgttgagc cgctcgtcat acatcccgat
    12001 ggatttcatc atcgccagat gctgggcccg gtcgacaaaa cagaaaacat acgccccggt
    12061 ctgccaggcg agcaccacca tatcttccag atgctcgctg gtcggcatga tgcagcgctc
    12121 gccgttccgg tcctccgcgt cttcaataaa taccatgtac agcgccataa tccctcactc
    12181 cgttgtcata aatttaaagc acgcaaacaa ccgttcacga tccagctctg ccgttttgcg
    12241 ggcctcgccg gtctgtgggt tcacgatttc atccaccgac aggattgccc gctgcaccct
    12301 gacctgcgtc gcccggtccg ggcagatgta ccagatttca tcgatgccgt tagctttgcg
    12361 gttgaacaga tacccggaca ccacttcctg ataccggcga cggctcttga cggtgcgctc
    12421 cacctcaaac gccaccgttt taccgtccag ctccgccagg gcgtccggca ctttcatgcc
    12481 tttaagactc agacggtgca gaatgcgcca gccggtggcc cctctggctt ccatatcaag
    12541 gcgcagggat tgcacggcca gccggtgcgg cagatgtgct gccgacaccc ttgacggctg
    12601 aaacggaata acatccgcca gcggttcgtc ctcgtcgaac gagaacgcca cgccatgcgg
    12661 cgtcagcccc cacacgctga cctgacggcc gtccaccgga tatttggtcc ggaccagcag
    12721 ccctttcgcc accaggctgt cgaggaagcg gtagaccggc tgcaccgccg caatccccag
    12781 ccgccgcgca accagctccg ccgtggaaca cagctcttcc cgcaaccagc gcagggtcag
    12841 ccgggttttc tccgcgttcc gcgcctgtcg tttcgcgtgg ctgacgttgt acagctccag
    12901 cgccatcagt aaatccccgc aaaatcatca tccgctttcg gcccgccgcc gtcggccggg
    12961 ggccggaact ccgccagggg atcggttttc gccagcaccg ggaaacgctg caacgggatt
    13021 tcccggcgct caacccgcag cggactgctg aacgccatcc gggccacacc cagcccggtc
    13081 atgaccgcga acccgtccgg caggtgttgc agggtgttca cgtcaaacag cggccgcgcc
    13141 tccttctgga tgaagctgtc cccgctgata tgctccacgt tccccgcctc ccggctggca
    13201 cggcggcgct ccacgtccac cctgatttcc ccggtctgcc ccgccgccca ctgcgcggac
    13261 tccaggctgg ccgcccggta aaaccagcgg atcggcgtgt tatccagtac cgtggttttc
    13321 acaaattcag cgggcagatc ctgcccgcac tgcccgaaat cgcccagcga ctggtgcgcg
    13381 agcaacagat tgcagtcccg gctgcgcagc gtccccagtg cgttcagtac atacttcgac
    13441 agcagatatt taatttcatc gagcatcacg ctgacgtgtg gccactcccg gaactcgtcc
    13501 cgcgcaatga tgatttgcgc gcagcgggca aacagcattt tttgcacacg gatcaccgcc
    13561 tcgtcgtcca tcgagccgat aacgtacagg cagccgccgc cgttgataat ccccgccaca
    13621 tcgatgccac tgtccg
//
