LOCUS       OW849463                9923 bp    DNA     circular BCT 17-MAY-2022
DEFINITION  Enterobacter cloacae isolate 78 genome assembly, plasmid: P6.
ACCESSION   OW849463
VERSION     OW849463.1
DBLINK      BioProject: PRJEB42440
            BioSample: SAMEA7962766
KEYWORDS    .
SOURCE      Enterobacter cloacae
  ORGANISM  Enterobacter cloacae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1
  AUTHORS   Alioto,T., Alioto,T. and Gomez Garrido,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAY-2022) CNAG-CRG, CNAG, Spain
FEATURES             Location/Qualifiers
     source          1..9923
                     /organism="Enterobacter cloacae"
                     /mol_type="genomic DNA"
                     /isolate="78"
                     /isolation_source="Hospital Universitario Central de
                     Asturias (Oviedo)"
                     /db_xref="taxon:550"
                     /plasmid="P6"
     gene            complement(1..3836)
                     /locus_tag="AI2688V1_REPA000000086"
     repeat_region   complement(1..3836)
                     /locus_tag="AI2688V1_REPA000000086"
                     /note="Tn5393_unknown_unknown"
                     /rpt_family="IS"
     gene            347..967
                     /locus_tag="AI2688V1_5146"
     mRNA            347..967
                     /locus_tag="AI2688V1_5146"
                     /note="AI2688v1_5146.mrna"
     CDS             347..967
                     /locus_tag="AI2688V1_5146"
                     /note="long variant; AI2688v1_5146.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH3993173.1"
                     /translation="MANTLRSTVETADDPVVGFDHCVGQHRLPFRDANSQDRKPPVLRE
                     IAHAVGIIPFTLPAQTSHPMGRNAGKQILGEIDALQIFEPVEQPVGRRRVRARLELAQP
                     HKTGHPIISRLLEQCQQLFSDRHRQPTGDPRLDASLGIDESRGTKPLDRGCRGKDSAGA
                     SALGYEATGDILVRHRHLGFSEQPFLQLARTTSGEGAEAVEPP"
                     /name="hypothetical protein"
     exon            347..967
                     /locus_tag="AI2688V1_5146"
                     /note="AI2688v1_5146.mrna"
                     /number=1
     gene            977..1225
                     /locus_tag="AI2688V1_5147"
     mRNA            977..1225
                     /locus_tag="AI2688V1_5147"
                     /note="AI2688v1_5147.mrna"
     CDS             977..1225
                     /locus_tag="AI2688V1_5147"
                     /note="long variant; AI2688v1_5147.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH3993198.1"
                     /translation="MLVPCFLAGSIVYEIVGTQAKLRSDKFDDLCRDQFAWSQHPAGIA
                     QDTQLQGEAEPVVSAPTQPDMPKVFITQRIVLEQIRL"
                     /name="hypothetical protein"
     exon            977..1225
                     /locus_tag="AI2688V1_5147"
                     /note="AI2688v1_5147.mrna"
                     /number=1
     gene            1411..2025
                     /locus_tag="AI2688V1_5148"
     mRNA            1411..2025
                     /locus_tag="AI2688V1_5148"
                     /note="AI2688v1_5148.mrna"
     CDS             1411..2025
                     /locus_tag="AI2688V1_5148"
                     /note="long variant; AI2688v1_5148.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-invertase hin"
                     /protein_id="CAH3993222.1"
                     /translation="MLIGYARVSKADGSQSLDLQHDALRAAGVERDNIYDDLASGGRDD
                     RPGLTACLKSLRDGDVLVVWKLDRLGRSLAHLVNTVKELSDRKIGLRVLTGKGAQIDTT
                     TASGRMVFGIFATLAEFERDLIRERTMAGLASARARGRKGGRKFALTKAQVRLAQAAMA
                     QRDTSVSDLCKELGIERVTLYRYVGPKGELRDHGKHVLGLT"
                     /name="DNA-invertase hin"
     exon            1411..2025
                     /locus_tag="AI2688V1_5148"
                     /note="AI2688v1_5148.mrna"
                     /number=1
     gene            <2091..2894
                     /locus_tag="AI2688V1_5166"
     mRNA            2091..2894
                     /locus_tag="AI2688V1_5166"
                     /note="AI2688v1_5166.mrna"
     CDS             <2091..2894
                     /locus_tag="AI2688V1_5166"
                     /note="short variant; AI2688v1_5166.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="APH(3'')-Ib"
                     /protein_id="CAH3993248.1"
                     /translation="LNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASRR
                     GELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAWPS
                     MGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLLARV
                     ERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLALMIA
                     NAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
                     /name="APH(3'')-Ib"
     exon            2091..2894
                     /locus_tag="AI2688V1_5166"
                     /note="AI2688v1_5166.mrna"
                     /number=1
     gene            2475..2894
                     /locus_tag="AI2688V1_5149"
     mRNA            2475..2894
                     /locus_tag="AI2688V1_5149"
                     /note="AI2688v1_5149.mrna"
     CDS             2475..2894
                     /locus_tag="AI2688V1_5149"
                     /note="long variant; AI2688v1_5149.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Aminoglycoside 3'-phosphotransferase"
                     /protein_id="CAH3993274.1"
                     /translation="MFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLLARVERELPVRLDQ
                     ERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLALMIANAEENWAAPD
                     EAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
                     /name="Aminoglycoside 3'-phosphotransferase"
     exon            2475..2894
                     /locus_tag="AI2688V1_5149"
                     /note="AI2688v1_5149.mrna"
                     /number=1
     gene            2894..3730
                     /locus_tag="AI2688V1_5150"
     mRNA            2894..3730
                     /locus_tag="AI2688V1_5150"
                     /note="AI2688v1_5150.mrna"
     CDS             2894..3730
                     /locus_tag="AI2688V1_5150"
                     /note="long variant; AI2688v1_5150.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH3993306.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="hypothetical protein"
     exon            2894..3730
                     /locus_tag="AI2688V1_5150"
                     /note="AI2688v1_5150.mrna"
                     /number=1
     gene            complement(3965..4180)
                     /locus_tag="AI2688V1_5151"
     mRNA            complement(3965..4180)
                     /locus_tag="AI2688V1_5151"
                     /note="AI2688v1_5151.mrna"
     CDS             complement(3965..4180)
                     /locus_tag="AI2688V1_5151"
                     /note="long variant; AI2688v1_5151.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH3993332.1"
                     /translation="MTELEKQLLTALEQLHQDYSQRLDEWESAFAEWQKMSGLMQRENA
                     VLNERVSDLSTQVLSLSEQLRRLSGN"
                     /name="hypothetical protein"
     exon            complement(3965..4180)
                     /locus_tag="AI2688V1_5151"
                     /note="AI2688v1_5151.mrna"
                     /number=1
     gene            complement(4187..4678)
                     /locus_tag="AI2688V1_5152"
     mRNA            complement(4187..4678)
                     /locus_tag="AI2688V1_5152"
                     /note="AI2688v1_5152.mrna"
     CDS             complement(4187..4678)
                     /locus_tag="AI2688V1_5152"
                     /note="long variant; AI2688v1_5152.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH3993360.1"
                     /translation="MSSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEQSVRAELSASA
                     RRISDAISAHEQSMSEAMEKNRRSVLLTAGRAWLTILMVSALLIATSGSILWWQGQQIT
                     DNYTHLRQQEDTLAKMTARTWGVRYQESSDGRRFLILPPGMQAEAIPYDGTTWIRLKQE
                     "
                     /name="hypothetical protein"
     exon            complement(4187..4678)
                     /locus_tag="AI2688V1_5152"
                     /note="AI2688v1_5152.mrna"
                     /number=1
     gene            complement(5356..5679)
                     /locus_tag="AI2688V1_5153"
     mRNA            complement(5356..5679)
                     /locus_tag="AI2688V1_5153"
                     /note="AI2688v1_5153.mrna"
     CDS             complement(5356..5679)
                     /locus_tag="AI2688V1_5153"
                     /note="long variant; AI2688v1_5153.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="Mobilization protein MbeC"
                     /protein_id="CAH3993392.1"
                     /translation="MLTMWVTEDEHRRLLERCDGRQLAAWMRQTCLDEKPARTGKLPSI
                     SPALLRQLAGMGNNLNQIARRVNAGGGTGHDRVQIVAALMAIDAGLEQLRHAVLEKGTD
                     DDH"
                     /name="Mobilization protein MbeC"
     exon            complement(5356..5679)
                     /locus_tag="AI2688V1_5153"
                     /note="AI2688v1_5153.mrna"
                     /number=1
     gene            complement(6711..7079)
                     /locus_tag="AI2688V1_5154"
     mRNA            complement(6711..7079)
                     /locus_tag="AI2688V1_5154"
                     /note="AI2688v1_5154.mrna"
     CDS             complement(6711..7079)
                     /locus_tag="AI2688V1_5154"
                     /note="long variant; AI2688v1_5154.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH3993420.1"
                     /translation="MALLISLVVVAGLYYQFWYKPHRAPILRIWGIAPDGQEFRLLLTE
                     HGEKEAVLLFGKKSFVAVPDTQNLYGGCYYLYLEDAHKNELLIELNESDLYPGGAIELQ
                     HNGGRKIHCEILKVRWSR"
                     /name="hypothetical protein"
     exon            complement(6711..7079)
                     /locus_tag="AI2688V1_5154"
                     /note="AI2688v1_5154.mrna"
                     /number=1
     gene            7239..7472
                     /locus_tag="AI2688V1_5155"
     mRNA            7239..7472
                     /locus_tag="AI2688V1_5155"
                     /note="AI2688v1_5155.mrna"
     CDS             7239..7472
                     /locus_tag="AI2688V1_5155"
                     /note="long variant; AI2688v1_5155.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein YgdR"
                     /protein_id="CAH3993447.1"
                     /translation="MNKKTLLAAMMVALVTFAAAGCSSNQEIKTTDGRTIVTDGKPKVD
                     SDTGLVSYKDAHTGRTEQINRDKITNMSELDN"
                     /name="putative lipoprotein YgdR"
     exon            7239..7472
                     /locus_tag="AI2688V1_5155"
                     /note="AI2688v1_5155.mrna"
                     /number=1
     gene            <7494..7721
                     /locus_tag="AI2688V1_5156"
     mRNA            7494..7721
                     /locus_tag="AI2688V1_5156"
                     /note="AI2688v1_5156.mrna"
     CDS             <7494..7721
                     /locus_tag="AI2688V1_5156"
                     /note="short variant; AI2688v1_5156.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein YgdR"
                     /protein_id="CAH3993477.1"
                     /translation="LKKIFVSVFAAAVALSALTGCTRTSYAIHTNDGRTIVSDGKPTES
                     DSGLLGYKDANGVKQQINKADVKEVSEIPH"
                     /name="putative lipoprotein YgdR"
     exon            7494..7721
                     /locus_tag="AI2688V1_5156"
                     /note="AI2688v1_5156.mrna"
                     /number=1
     gene            complement(8097..8216)
                     /locus_tag="AI2688V1_5157"
     mRNA            complement(8097..8216)
                     /locus_tag="AI2688V1_5157"
                     /note="AI2688v1_5157.mrna"
     CDS             complement(8097..8216)
                     /locus_tag="AI2688V1_5157"
                     /note="long variant; AI2688v1_5157.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH3993504.1"
                     /translation="MKLLNVIEAVLNCLHLAAELWEWLEKHLPVFGAFTLFLG"
                     /name="hypothetical protein"
     exon            complement(8097..8216)
                     /locus_tag="AI2688V1_5157"
                     /note="AI2688v1_5157.mrna"
                     /number=1
     gene            complement(8290..9923)
                     /locus_tag="AI2688V1_REPA000000087"
     repeat_region   complement(8290..9923)
                     /locus_tag="AI2688V1_REPA000000087"
                     /note="Tn5393_unknown_unknown"
                     /rpt_family="IS"
     gene            complement(8323..>9843)
                     /locus_tag="AI2688V1_5158"
     mRNA            complement(8323..9843)
                     /locus_tag="AI2688V1_5158"
                     /note="AI2688v1_5158.mrna"
     CDS             complement(8323..>9843)
                     /locus_tag="AI2688V1_5158"
                     /note="short variant; AI2688v1_5158.mrna"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH3993531.1"
                     /translation="VLFHLRDAFRSGDVWLTRSRRYGDLKHALVPAQSIAEGGRLAVPL
                     RPEEWLADRQARLDMRLRELGRAARAGTIPGGSIENGVLHIEKLEAAAPTGAEDLVLDL
                     YKQIPPTRITDLLLEVDAATGFTEAFTHLRTGAPCADRIGLMNVILAEGINLGLRKMAD
                     ATNTHTFWELIRIGRWHVEGEAYDRALAMVVEAQAALPMARFWGMGTSASSDGQFFVAT
                     EQGEAMNLVNAKYGNTPGLKAYSHVSDQYAPFATQVIPATASEAPYILDGLLMNDAGRH
                     IREQFTDTGGFTDHVFAACAILGYRFAPRIRDLPSKRLYAFNPSAAPAHLRALIGGKVN
                     QAMIERNWPDILRIAATIAAGTVAPSQILRKLASYPRQNELATALREVGRVERTLFMID
                     WILDAELQRRAQIGLNKGEAHHALKRAISFHRRGEIRDRSAEGQHYRIAGMNLLAAIII
                     FWNTMKLGEVVANQKRDGKLLSPDLLAHVSPLGWEHINLTGEYRWPKP"
                     /name="hypothetical protein"
     exon            complement(8323..9843)
                     /locus_tag="AI2688V1_5158"
                     /note="AI2688v1_5158.mrna"
                     /number=1
     ARG             2895..3727
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             2092..2891
                     /name="aph(3'')-Ib"
                     /gene="aph(3'')-Ib"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3'')-Ib"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(5786..5864)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="98.75"
                     /coverage="100.0"
                     /evalue="2.7400000000000003e-32"
     Typing          5940..6428
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="86.345"
                     /coverage="94.0"
                     /evalue="1.69e-147"
     Typing          complement(3874..5366)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="90.8"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(5363..5679)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="92.453"
                     /coverage="99.0"
                     /evalue="9.92e-61"
ORIGIN
        1 tggtcatcgc ggcatcgttc aaaccggtac gaagggccgt caccgcttcc agaagcggca
       61 gtgcaacggg cgcagctcgc agatcgagca ggcgcaacat gcgtggagcg tatcggcgga
      121 agcggtgata accgtcgagc acatgattga gcggatcgtc ggccatggtg gcggtcagcc
      181 tggttgccat tgcaacaagg gtttttaagc cgtcccaccc tgacccactc gcgatgacat
      241 cgcccagcgg ctggccatca tcctgtgcat cgaccagggc gcccccgatc tcggcgaagg
      301 atttcagggt gtcacgcacc acccccgctt cgtctgcgac ctttgcatgg caaatacgct
      361 ccgaagcacg gtagagacgg ccgacgatcc ggtcgtgggt ttcgaccact gcgtcggcca
      421 acatcgcctg ccattccgag acgcaaacag ccaagatcgc aagccgcctg tcctccggga
      481 gatcgcgcat gccgtcggca taataccgtt caccctgcct gcgcagacga gtcacccgat
      541 gggcaggaac gccggcaagc agatcctcgg ggagatcgat gcgttgcaga tattcgagcc
      601 ggtcgagcag ccggttggcc gacgaagagt tcgagccagg ctcgaactgg cgcagccaca
      661 caaaacgggt cacccgatca tcagccgtct cctcgagcaa tgccagcaac tgttctcgga
      721 tcgacatagg cagccgactg gcgatcctcg tctcgatgcg tcgctcggca tcgacgagag
      781 ccgcggcaca aagccgctcg atcgtggatg tcgcgggaag gacagtgcgg gtgcgtcggc
      841 actcggctac gaagcgacgg gcgatatcct cgttcgacac cgccatctcg gcttctcgga
      901 acaaccattc cttcagctcg ctcgcaccac gtccggagaa ggtgcggaag ccgtagagcc
      961 cccgtaactc ggcaagatgc tcgtgccgtg tttcctcgcg ggcagcatag tctacgagat
     1021 cgtcggcacc caggccaagc tgcgctccga taaattcgat gacctctgca gggatcagtt
     1081 cgcctggagc cagcacccgg ccgggatagc gcaggacaca caattgcagg gcgaagccga
     1141 acctgttgtg agcgcgccga cgcagcctga tatgcccaag gtcttcatca ctcagcgtat
     1201 agtgcttgag caaatccgtc tgtgaagtcg gcaagcgcaa cagcgcgtct ttctgccgat
     1261 cggttagagt gacgcgacgc ggcatacatg ttcctttttc aaaatctgat agcgttcaag
     1321 acgctttgtt tatgaagctg gttgagatac atttccagag gtcaatgcaa tcgtggccga
     1381 agcgccgcct caaaccaacg tttgtgatac atgctgatcg gatatgcccg cgtctccaaa
     1441 gccgatggct cgcagtctct cgacctgcag cacgacgcct tgcgcgccgc aggtgtcgaa
     1501 cgggacaata tctatgatga tcttgcttcc ggcggtcgtg atgatcgccc tggcttgact
     1561 gcctgcctca agtcattgcg tgacggcgat gtgctggtgg tctggaagct cgatcgcctc
     1621 ggacgatcgc ttgcccatct ggtcaacacg gtgaaggagc tgtcagaccg caagatcggc
     1681 ctgcgggttc tgactggaaa gggcgctcag atcgacacca cgactgcgtc cggtcgcatg
     1741 gtgttcggaa tcttcgccac cttggccgag ttcgagcggg atctgatccg agagcgcacc
     1801 atggcgggtc tcgcctccgc gagagcgcgc ggtcgcaagg gcggacgaaa attcgcgctc
     1861 accaaagctc aggtgcgtct cgcgcaagcc gccatggccc agcgcgatac ttcagtttcc
     1921 gatctctgca aggaactcgg catcgagcgc gtcactctct accgatatgt cggtcccaaa
     1981 ggcgagctca gagaccatgg aaagcatgtt ctcggactta cgtagcaact cgtttctttt
     2041 cgcaggttga gccacctccg cgcttcatca gaaaactgaa ggaacctcca ttgaatcgaa
     2101 ctaatatttt ttttggtgaa tcgcattctg actggttgcc tgtcagaggc ggagaatctg
     2161 gtgattttgt ttttcgacgt ggtgacgggc atgccttcgc gaaaatcgca cctgcttccc
     2221 gccgcggtga gctcgctgga gagcgtgacc gcctcatttg gctcaaaggt cgaggtgtgg
     2281 cttgccccga ggtgatcaac tggcaggagg aacaggaggg tgcatgcttg gtgataacgg
     2341 caattccggg agtaccggcg gctgatctgt ctggagcgga tttgctcaaa gcgtggccgt
     2401 caatggggca gcaacttggc gctgttcaca gcctatcggt tgatcaatgt ccgtttgagc
     2461 gcaggctgtc gcgaatgttc ggacgcgccg ttgatgtggt gtcccgcaat gccgtcaatc
     2521 ccgacttctt accggacgag gacaagagta cgccgcagct cgatcttttg gctcgtgtcg
     2581 aacgagagct accggtgcgg ctcgaccaag agcgcaccga tatggttgtt tgccatggtg
     2641 atccctgcat gccgaacttc atggtggacc ctaaaactct tcaatgcacg ggtctgatcg
     2701 accttgggcg gctcggaaca gcagatcgct atgccgattt ggcactcatg attgctaacg
     2761 ccgaagagaa ctgggcagcg ccagatgaag cagagcgcgc cttcgctgtc ctattcaatg
     2821 tattggggat cgaagccccc gaccgcgaac gccttgcctt ctatctgcga ttggaccctc
     2881 tgacttgggg ttgatgttca tgccgcctgt ttttcctgct cattggcacg tttcgcaacc
     2941 tgttctcatt gcggacacct tttccagcct cgtttggaaa gtttcattgc cagacgggac
     3001 tcctgcaatc gtcaagggat tgaaacctat agaagacatt gctgatgaac tgcgcggggc
     3061 cgactatctg gtatggcgca atgggagggg agcagtccgg ttgctcggtc gtgagaacaa
     3121 tctgatgttg ctcgaatatg ccggggagcg aatgctctct cacatcgttg ccgagcacgg
     3181 cgactaccag gcgaccgaaa ttgcagcgga actaatggcg aagctgtatg ccgcatctga
     3241 ggaacccctg ccttctgccc ttctcccgat ccgggatcgc tttgcagctt tgtttcagcg
     3301 ggcgcgcgat gatcaaaacg caggttgtca aactgactac gtccacgcgg cgattatagc
     3361 cgatcaaatg atgagcaatg cctcggaact gcgtgggcta catggcgatc tgcatcatga
     3421 aaacatcatg ttctccagtc gcggctggct ggtgatagat cccgtcggtc tggtcggtga
     3481 agtgggcttt ggcgccgcca atatgttcta cgatccggct gacagagacg acctttgtct
     3541 cgatcctaga cgcattgcac agatggcgga cgcattctct cgtgcgctgg acgtcgatcc
     3601 gcgtcgcctg ctcgaccagg cgtacgctta tgggtgcctt tccgcagctt ggaacgcgga
     3661 tggagaagag gagcaacgcg atctagctat cgcggccgcg atcaagcagg tgcgacagac
     3721 gtcatactag atatcaagcg acttctccta tcccctggga acacatcaat cttaccggag
     3781 aatatcgttg gccaaagcct tagcgtagga tttcgccctc tcccgcaaac gaccccttct
     3841 tggggtttat cacgggccgg catccgtcag cccagcgtcg gtcctttgta ggttttctgc
     3901 ggctggcgct ccagctccag tgttttctga tactcattct ccccctgccg gaactcggtg
     3961 gcattcagtt cccggacaag cggcgcagct gctcgcttaa actcagcacc tgcgtgctca
     4021 agtccgacac gcgctcgttc agcaccgcgt tctcccgttg cataagccca gacatcttct
     4081 gccattccgc gaaggcgctc tcccattcgt ccagcctttg cgagtagtcc tgatgtagct
     4141 gctctaatgc ggtcagcaac tgcttttcca gctctgtcat tttccgctac tcctgtttca
     4201 ggcggatcca ggtcgtcccg tcgtagggga tggcttcggc ttgcatcccc ggcggcagga
     4261 taaggaacct ccggccgtcg ctgctctcct gatagcgcac tccccacgtc cgggcagtca
     4321 ttttcgccag ggtatcttcc tgctgacgaa gatgtgtgta attgtcggtt atctgctgcc
     4381 cctgccacca cagaatgctc ccgctcgtgg cgatcagcag cgctgacacc atcaggatgg
     4441 tgagccatgc cctcccggct gtcagcagca cgctccgccg gtttttctcc atcgcctcgc
     4501 tcatactctg ttcgtgggcg ctgatggcgt cgctgattct cctcgcgctt gcgctcagtt
     4561 ccgctctgac agactgctcg tgctcgctga atgcggcttt cagcatctcg ccggtactct
     4621 gctgctgcgc tttcgatttc tgctccaagt ccttcgccag cgttaaaaga ctgctcatag
     4681 atggctccct tcagtcggat gtttcgcccc ccgtccgggt cggcaatgct gatgctgctt
     4741 ttcgtgctgc gcaccacctc aaaacctgcg ctttccagcg cctcagtgac gtcctgacgg
     4801 gttttcagct ccccggatga ggcaagggca agcaggccgc gcgtaatcgc ctgggcagct
     4861 tcctgcttcg cttccggcag cgcggacggc gtgaccagcg cccgccggtt ttccggcgcg
     4921 ttcgggtcgt gcagccccag ccggccgttg accaccgtct gccaggcatc gatgcgcggc
     4981 cggtcggcgc ggtcgtagta cggctggagc cgcctgccgg tcagcagctc ggtattgggg
     5041 atcagaaagt tcagctccag acgccccttg tccgcgtgct ccacccacag aatgctgtac
     5101 tgatctttat cgaggccggg catcagaaca cgctcgaagc tggccatcag tttttcccgc
     5161 tggccgggag gcagatctgc ctccgcaaac gacagtacgc cggaggtgta tttcttcacg
     5221 taaggcgaca catcaatcag ctcccggact tcttccggct tgccctgcag gacggtggcg
     5281 ccttcacgct gccggtcttt acccagcaaa tagtccaccg gcccggcgcc accgccgcga
     5341 ccgcgcggat gaaatttaat gatcatcgtc cgttcctttc tcaagaacgg cgtgccgcag
     5401 ctgctcaagg ccggcatcga ttgccatcag cgccgccaca atctgcaccc tgtcatggcc
     5461 ggtaccgccg ccggcgttaa cgcggcgggc tatctggttc aggttgttgc ccatgccggc
     5521 aagctggcgc agcagcgccg gcgagatcga gggtagcttt ccggtacgcg caggcttttc
     5581 atcaagacag gtctgccgca tccacgccgc cagctgcctg ccgtcacagc gttcgagcag
     5641 ccgccggtgc tcgtcctccg tcacccacat ggtgagcatc ttgttccgtt tctctgacaa
     5701 accggtctcc tgataacgcc gggacgggcg ggaaagcctt tcccggtcgg cgcggggttg
     5761 gacaagccgc aggcgcgtca ggcttttggc gggtttcggg gcgcagccct gaaccagtca
     5821 cgtagcgcta gcggagtgta tactggctta ctatggtggc acgacgggaa tcgggatgaa
     5881 atagtcagtc ataaaaactg tgagatgagg ctcaggtgcg taaggggctg atgcctgtcc
     5941 cggtggatat tccgcttcct cgctcactga ctcgctacgc tcggtcgttc ggctgcggcg
     6001 agcggtacgg actcacggat aaagacgtgg gggggaaata cgtgaatgca ggaggggaaa
     6061 aaaggatgcg gcgctgccgg ttttccatag gctccgcccc cctgacaagc atcacagaat
     6121 ctgacgctca aatcagtggt ggcgaaaccc gatgcggctt aaagatacca ggcgtttccc
     6181 cctgatggct ccctcgtgct cccccgcatt cctgcctttc ggtttaccgg tgtcattccg
     6241 ctgttatggc cgcggtttct cattccacgc ctgacactca gttccgcgaa ggcagttcgc
     6301 tccaggattg actgtatgca cgaacccccc gttcagtccg actgctgcgc cttatccggt
     6361 aactatcgtc ttgagtccaa cccggaaaga cacgaaaaat cgctactggc agcagccatt
     6421 agtaactgga ggtatacgag agacaaatta agaggtcttg aagtatgggc ctgagagagg
     6481 ctacactgaa agaacatttt tggtttctgc ggtctcgtat acccagttac ctggttaagc
     6541 agttccccaa ctgacttaac cttcgatcaa accacctccc caggtggttt tttcgttttc
     6601 agagcaagag attacgactg taacgacagg atcacaagaa gatcatttac tcagagagac
     6661 taactaccac tatgtttgcc tatcaacata cttaggaaac attacttgag ttaacgactc
     6721 caccttactt ttagtatctc gcaatgaatc ttccgaccgc cgttgtgttg aagttctatt
     6781 gcgccaccgg ggtataaatc actttcgttt aactcaatta aaagctcgtt cttgtgagca
     6841 tcctctaaat aaaggtaata acacccacca taaaggttct gcgtatctgg cacggcaaca
     6901 aaagatttct ttccgaacag taaaacagcc tctttttctc catgctctgt tagcaataat
     6961 cgaaattctt gtccatcagg cgcgatcccc catatacgca agatcggcgc tctatgtggc
     7021 ttataccaaa attgatagta aagacctgcc actacaacca gtgaaattaa taaggccatt
     7081 tcaatcctca aaaacaagca acattccaaa atcgtttttc attcattttt actgctgggc
     7141 atgatgccca ccttcaatcc tcttttcgca tgaaaaaacg acctatactt agatggttag
     7201 tgaccatatc cactttacct ttaagcaggg aacctattat gaataaaaaa acgctgttgg
     7261 cggccatgat ggtcgcgttg gtgacctttg ccgctgctgg atgttcttca aaccaagaaa
     7321 taaaaaccac agatggtcgc actatcgtta cagacggcaa acccaaagtt gacagtgata
     7381 cggggttagt atcctacaaa gatgcccata caggccgaac cgaacagatc aaccgtgaca
     7441 aaattaccaa catgagtgaa ctagacaact gatacggata aaaggagctg gctttgaaaa
     7501 agatttttgt ttcagtgttc gcagcggcag ttgcgctttc agccctaacc ggctgcacgc
     7561 gcacaagcta tgccatccac accaacgacg ggcgtacaat tgtcagcgac ggcaagccta
     7621 cagaatcaga ctcaggcctg ctgggctata aagacgcaaa tggtgtcaaa cagcagatca
     7681 ataaagccga cgttaaagaa gtctctgaaa ttccgcattg aggcatcgct ctctccgaaa
     7741 agggccgcta atgcggccct tttctttatc tgccccaaca acaggcaaaa aaagcccccg
     7801 ctgggggcca aatacctgca gtggctggat agtactgcat tcctgatgaa ggagacgaat
     7861 aagtatgggc cggatttttg cgtctgcagg ctcggtcgcc acaatttttc cgtacccgcc
     7921 aggcatcatg cttttaccat aacatccgtt gtctgcaccg ccggatcggc actgacggcg
     7981 cagacggcac ctggcacccg aaaacccggc ttaagcaacg ctacatcctc cgttaagccg
     8041 ggagataatt tttacccgac tgcatagcca tgcagccagg tgaatgacgg caggattcag
     8101 cccaaaaaca gcgtgaaggc cccgaaaacc ggcaaatgct tttccagcca ctcccacagt
     8161 tctgccgcca gatgcaggca gttaagtaca gcttcaataa cattaagcag tttcataatt
     8221 ccccctggta taggccgtga tctttgcatc acgacgtatt tagcggggaa tttcgcagcc
     8281 cttcttcttg gggtcgtttg cgggaggggg cggaatccta cgctaaggct ttggccagcg
     8341 atattctccg gtgagattga tgtgttccca tccgagcggc gaaacatggg ccaagagatc
     8401 gggcgatagc agctttccat cgcgtttctg gtttgcaacg acctcgccga gcttcatggt
     8461 gttccagaag atgatgatgg cggcgagcag attcatgccg gcgatgcggt aatgctggcc
     8521 ttcggcggaa cggtcgcgga tttcaccgcg gcggtggaag ctgattgccc gcttcagcgc
     8581 atgatgagct tcgcctttgt tgagcccgat ctgggcacgc cgttggagtt cggcatccag
     8641 aatccagtcg atcatgaaca gggtgcgctc gacgcgaccg acttcccgca gggctgtcgc
     8701 gagctcgttc tgccgcggat aggaggcgag tttccgcaga atctggcttg gcgcgacggt
     8761 cccggcagca atggtggcgg cgatgcgcag gatgtcgggc caattgcgct cgatcatggc
     8821 ttggttgacc tttccgccga tcaacgctcg caggtgcgcc ggggcggccg acggattgaa
     8881 cgcgtagagc cgtttggatg gcaggtcgcg gatgcgcgga gcgaaccggt agccgagaat
     8941 ggcacatgcg gcaaagacgt gatcggtgaa gccgcccgtg tcggtgaact gctcgcggat
     9001 atggcgtcca gcatcgttca tcagcaggcc atcgaggatg taaggcgctt cgcttgccgt
     9061 tgcaggaatc acctgggttg cgaacggcgc atattggtcg gagacgtggc tataggcttt
     9121 caggcccggg gtattgccat atttcgcgtt gaccaggttc atggcctcac cttgctctgt
     9181 agcgacgaag aactgtccgt cgctcgaagc cgacgtgccc atgccccaga accgggccat
     9241 gggtaacgct gcctgtgcct cgaccaccat ggccagcgcc cggtcatagg cttcgccctc
     9301 gacatgccac cgtccaatgc ggatcaattc ccagaaggtg tgggtgtttg tcgcatccgc
     9361 cattttgcgc aagccgaggt tgatcccttc cgccaagata acgttcatta gcccgatccg
     9421 gtcagcgcag ggtgctcctg tgcgcagatg ggtgaacgct tcggtgaagc cggtcgccgc
     9481 atccacctcc agcaggagat cggtgatgcg cgtgggcggg atctgcttgt agagatcgag
     9541 caccagatct tcggcgcctg tcggcgcggc ggcttcgagt ttctcgatat gcagaacgcc
     9601 gttttcaatc gacccgcccg ggatcgtgcc tgcgcgagcg gcacggccaa gctcgcgcaa
     9661 ccgcatgtcg aggcgagctt gccggtctgc cagccattcc tccggccgca atggcacagc
     9721 gagacgaccg ccttccgcga tggattgtgc cggaacgagt gcgtgtttca gatcgccata
     9781 gcgccgggac ctagtaagcc agacatctcc ggagcggaac gcatcgcgca gatggaacag
     9841 caccgcgatc tcccataggc gagcgtcgcc agccctctgg gcccgaaggt ggcgatgcca
     9901 tttcgagctg ggccgcaaga agc
//
