LOCUS       NZ_OY978496             6141 bp    DNA     circular CON 21-DEC-2023
DEFINITION  Klebsiella pneumoniae strain KP36482022BGR isolate KP36482022
            plasmid P_KP36482022_2, complete sequence.
ACCESSION   NZ_OY978496
VERSION     NZ_OY978496.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA114785898
            Assembly: GCF_963854865.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Ivanov,I., Teneva,D. and Stoikov,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-DEC-2023) NCIPD, CMAR, Yanko Sakazov 26 Sofia,
            Bulgaria
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/21/2023 00:03:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,494
            CDSs (total)                      :: 5,376
            Genes (coding)                    :: 5,161
            CDSs (with protein)               :: 5,161
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 215
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 143 of 215
            Pseudo Genes (incomplete)         :: 80 of 215
            Pseudo Genes (internal stop)      :: 21 of 215
            Pseudo Genes (multiple problems)  :: 24 of 215
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OY978496.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6141
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP36482022BGR"
                     /isolate="KP36482022"
                     /isolation_source="human urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="P_KP36482022_2"
                     /geo_loc_name="Bulgaria"
                     /lat_lon="43.225887 N 27.936721 E"
                     /collection_date="2022-12-09"
     gene            complement(join(5848..6141,1..504))
                     /locus_tag="U9J21_RS27370"
                     /old_locus_tag="KP3648_27165"
     CDS             complement(join(5848..6141,1..504))
                     /locus_tag="U9J21_RS27370"
                     /old_locus_tag="KP3648_27165"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011071128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-48 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-232"
                     /protein_id="WP_043907054.1"
                     /translation="MRVLALSAVFLVASIIGMPAVAKEWQENKSWNAHFTEHKSQGVVV
                     LWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIAA
                     WNRDHDLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIR
                     ISATQQIAFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTSIEPKIGWW
                     VGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP"
                     /name="OXA-48 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-232"
     gene            848..1129
                     /locus_tag="U9J21_RS27375"
     CDS             848..1129
                     /locus_tag="U9J21_RS27375"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_043907053.1"
                     /translation="MGFFNLSKALEEVSDAFGAKETAIASAKLLGKGVVNLAHFAATTG
                     LDSVVKQTSNKVLNSESSTEEQREQAKKSAAWADARIAARNKAENTED"
                     /name="hypothetical protein"
     gene            complement(1411..2865)
                     /locus_tag="U9J21_RS27380"
     CDS             complement(1411..2865)
                     /locus_tag="U9J21_RS27380"
                     /inference="COORDINATES: protein motif:HMM:NF015397.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_064996073.1"
                     /translation="MIIKFHNRGVGRGSGPVGYLLGRDGNREGATLDRGNPAVIEALID
                     SSPYAKKYTSGVLSFAEADLPRATKDKLMSDFEKALLPGLEGNQYAVLWVEHRDKGRLE
                     LNFVVPNIELQSGKRLQPYFHKADNPRLDAWRTVVNGELKLHDPDDPLNRQAVITPKDL
                     PRGHKEAAQAITDGLLRMAGAGEIQSRDDVRKALQGAGFSVVRETKNSLSIADPDGGRN
                     IRLKGVLYEQDFRHGEGLRAELEAAGQRYREASDRRIHEARESYLRGVEIKRGENERRY
                     CRAQPENGLAVAQNVDLDAGQHRPVLERNERDPLVSGGIDSGAASHSPSLGREGRQAKA
                     DPVREEIGAPLRADLRPQSNRLGEGYLLDRAEGVLNDGIGAGIALRVRGFAERIRAAAQ
                     GMAGKLRELGEHVREHQTRGRDQQGSSRAIDEAGERLNAASGRLEQAAGGLDRASQQVA
                     KEREHRLLKALDRGWERGDRSRGFER"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(2846..3184)
                     /locus_tag="U9J21_RS27385"
                     /old_locus_tag="KP3648_27150"
     CDS             complement(2846..3184)
                     /locus_tag="U9J21_RS27385"
                     /old_locus_tag="KP3648_27150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_043907051.1"
                     /translation="MAGQPLKRLRSIKIRVSDAELERLRELCPKAQLAEWMREQCLGVA
                     QPQRRTPAPTVDPALLRQLAGMGNNLNQIARRVNSGEWGPLDRLRIIAELSAIGRELEE
                     LHHDHQIP"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            complement(3166..3558)
                     /locus_tag="U9J21_RS27390"
     CDS             complement(3166..3558)
                     /locus_tag="U9J21_RS27390"
                     /inference="COORDINATES: protein motif:HMM:NF037437.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin VbhA family protein"
                     /protein_id="WP_043907050.1"
                     /translation="MSTTQIEKDSRRKAVNGVISSFQLEGEAITDEFKILLEDYINGKI
                     STDEVLAMVSDEPTTTEYDYEITPRTLGLGGGWNLRLLENGEEVGGGVFPLPEHCDFRD
                     EKALQTLLDSLYEDALAEASAWLASR"
                     /name="antitoxin VbhA family protein"
     gene            complement(3966..4913)
                     /locus_tag="U9J21_RS27395"
                     /old_locus_tag="KP3648_27160"
     CDS             complement(3966..4913)
                     /locus_tag="U9J21_RS27395"
                     /old_locus_tag="KP3648_27160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_015060053.1"
                     /translation="MRKCAQLELFRERLPRKPYYSDELTTGLRIADVARALGARYIQPN
                     GPTHRHWIVFDVDHAAATLSWDDVGAPAPNITVTNKANGHAHLIYGLDTPIRTAPDGNA
                     APLRYAAAIEAALREKLGADMGYSGLICKNPLHEHWLVQVWEPRLYDLAWLSDYLDLSS
                     YNGRKSLPEYGLGRNCTLFEKTRLWAYKAIRQGWPDYPEWLAACVDRASGYNAQFEQPL
                     PANEVRHTAKSIAKWTHQHLSPAGFREEQARRGAKGGKVSKGGGRPSNSGKDKSDLLPE
                     VLRLKAQGYTNRDIADDLQISPSTVSVYLKRDRP"
                     /name="replication initiation protein"
     gene            <5289..5441
                     /locus_tag="U9J21_RS27400"
                     /pseudo=""
     CDS             <5289..5441
                     /locus_tag="U9J21_RS27400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015059985.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EreA family erythromycin esterase"
                     /name="EreA family erythromycin esterase"
     ARG             complement(5849..6141)
                     /name="OXA-232"
                     /gene="OXA-232"
                     /gene_name="OXA beta-lactamase; OXA-48-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="carbapenem; penam"
                     /identity="100.0"
                     /coverage="36.6"
     ARG             complement(2..504)
                     /name="OXA-833"
                     /gene="OXA-833"
                     /gene_name="OXA beta-lactamase; OXA-48-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="carbapenem; penam"
                     /identity="100.0"
                     /coverage="63.4"
     Typing          complement(3980..4901)
                     /name="rep_cluster_1195"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="81.974"
                     /coverage="98.0"
                     /evalue="0.0"
     Typing          complement(1415..2865)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.554"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ctgggtagcc gaaatgcgaa taccaccatc gagccaaaaa ctgtctacat tgcccgagat
       61 atcctcattg ccataatcga aggcgtgcag cattttactc atacgtgcct caccaatttg
      121 gcgggcaaat tcttgataaa caggcacaac tgagtacttc atcgcggtaa ttaagtcatg
      181 gtcacgattc caagcggcga tatcacgcgt ctgtccatcc cacttaaaga cttggtgttc
      241 atccttaacc acgcccaaat cgagggcgat caagctattg ggaattttaa aggtagatgc
      301 gggtaaaaat gcttggttcg cccgtttaag attattggta aatccttgct gcttattctc
      361 attccagagc acaactacgc cctgtgattt atgttcagta aagtgagcat tccaactttt
      421 gttttcttgc cattcctttg ctaccgctgg cattccgata atcgatgcca ccaaaaacac
      481 agccgataag gctaatacac gcataacgtc cccttgctta atgcaatata tccatacaaa
      541 ttaagtgcta agcttatcat tctctgccct ctcattccct agcaaactgc tgaccaattg
      601 tggcaacaat caggcacaag ctttaactat tacctaaatt ccacgtgtgt tttttattag
      661 cttcaaaaat cactatttca cgaagaattt agactgcttc tcacacattg taacattatt
      721 tacaaccacc tttcaatcat ttttgataaa tcattgattt catctttgct gcaatgatac
      781 ttaataaact ctgcaagtta tccacagagc aacactcaat tttattgatg atattcttag
      841 ggggagtatg ggatttttta acctatctaa agcgcttgag gaggtgtctg atgcttttgg
      901 ggctaaagaa accgcaatcg ctagtgccaa gttgttaggt aagggagttg ttaacctagc
      961 tcattttgca gcaacaacag gtttggattc ggtggtcaaa caaacgagca acaaagttct
     1021 caacagcgag tcttcaaccg aagaacaacg agaacaggct aaaaagtctg ccgcatgggc
     1081 agacgcgaga atcgccgcta gaaataaagc agaaaacacc gaagactagc tgaacgcaca
     1141 tttcgacaat gatgtggact acatcgttga tcataacttc acggtgcgct agcttccata
     1201 gaagccaact aataacaagg agttagcatg tctgattcag atttcaaaaa tagccctgag
     1261 tatgatgact ggattgaatc tggtggtaga gatgaagatt acagttacta ctatgaaaaa
     1321 tggcatagaa gaactcaacg ataattcccg ccgataaaag gaaagtgata gcactttcct
     1381 ttttttataa ctgacggccg ttttgttccg tcaacgctca aagcctcgcg atctgtctcc
     1441 acgctcccag cctcgatcca gtgccttcag gagcctgtgt tccctttctt ttgcaacttg
     1501 ctgactagcc cggtcaagcc ctccagctgc ttgctcaagc cgtccacttg ctgcgttaag
     1561 ccgttcacct gcctcgtcaa tcgctctgct gctgccctgc tgatctcggc ctcttgtttg
     1621 gtgctctcgt acatgctcgc caagttcgcg tagctttcct gccatgcctt gtgctgctgc
     1681 tcgtatgcgc tctgcaaagc ctcgaacgcg cagagcaatt cccgctccaa tcccgtcatt
     1741 tagtacccct tcggcacgat ccaataggta tccttccccc aaacggttgg attggggtcg
     1801 gagatctgca cgcaaaggtg ctccaatttc ttcccgcact gggtcagctt tagcttgccg
     1861 cccttctctg ccaaggcttg gagagtggct tgccgctccg ctatcaattc cccctgatac
     1921 cagaggatcc cgctcgttgc gctcaagaac aggacgatgc tgaccagcat ccagatccac
     1981 gttttgagca acagccagcc cattttctgg ctgtgctcgg caatagcggc gctcattttc
     2041 tcctcgcttg atttcaacgc cccggagata gctttctcgt gcctcgtgaa ttcttcggtc
     2101 agacgcttct cgatagcgtt ggcctgctgc ttcgagctct gctcgaagtc cttcgccatg
     2161 tctaaaatct tgctcataca gcaccccctt taatcggatg ttccgccccc cgtccgggtc
     2221 ggcaatgctc aggctgtttt tggtttcgcg taccacgctg aaacccgcac cctgcaaggc
     2281 tttgcgcaca tcatcgcggc tctggatctc ccctgctccg gccatgcgta aaagcccgtc
     2341 tgtaatggcc tgagcggcct ccttgtgccc cctcggcaaa tcctttggcg tgataacggc
     2401 ctgacggttt aacggatcgt ccgggtcgtg caatttcagc tccccgttta ccacggttcg
     2461 ccacgcatcg aggcgcggat tgtcggcctt gtggaagtag ggttgcagcc gcttcccgct
     2521 ctgcaattcg atgttcggga ctacaaaatt cagctccagc cgccccttgt cgcggtgctc
     2581 tacccacaaa acagcgtact ggttgccctc cagtccgggc aggagcgcct tttcaaagtc
     2641 gctcatcagc ttgtccttgg tcgccctggg taaatcagcc tcggcaaacg acagaacgcc
     2701 agaggtgtat tttttggcgt agggactgga atcaatcagg gcttcaatca ccgcagggtt
     2761 gccccggtcg agcgttgcgc cttcccggtt cccgtcacgg cccaacaagt agccaacagg
     2821 cccggagccc cggcctaccc cacggttatg gaatttgatg atcatggtgc agttcctcca
     2881 gctcgcggcc tatagcggac agctccgcta tgatgcgcag ccgatccaac ggcccccact
     2941 ccccggaatt aacgcgccgg gcgatctggt tcaggttgtt gcccattccg gccaactgcc
     3001 gcaagagcgc cggatctacg gtaggcgccg gcgttcggcg ctggggttgc gcaacaccga
     3061 gacattgctc ccgcatccac tccgccagtt gggccttggg gcagagctcc cgcaggcgct
     3121 caagctccgc atctgagacc cggatcttga tagagcggag gcgctttaac ggctggccag
     3181 ccatgcagag gcctccgcta aggcgtcctc atagaggcta tcgagtagcg tctggagcgc
     3241 cttttcatcc cgaaaatcgc agtgctccgg caaggggaaa acacccccgc cgacctcttc
     3301 gccgttctcc agcaaacgca gattccagcc cccgccaaga ccgagagtgc ggggggtgat
     3361 ttcgtagtcg tattccgttg ttgtgggttc gtcacttacc atagctaaca cctcatcggt
     3421 ggaaattttt ccattgatat aatcttcaag tagaattttg aattcatcgg ttatggcctc
     3481 cccctctagt tggaaactag aaataacgcc attgactgcc ttccttctcg aatctttctc
     3541 tatctgtgtt gttgacatag ggcctcgtcc attctccaga gccaagaagc caccgcgcag
     3601 accgtcccga aggggcggat cgagcggggg ccacaggggg tttcgggggg gcgtagcacc
     3661 cctgaacaag gccacagagg cccgagaccg cgaagcaggt agaggggcct ctgtgtagcc
     3721 ttgcttagta cattattcaa ccatgggcgg gatactgcaa gccctagagc aagatcaagg
     3781 gaaagagcgg ctccgtggat aactgctgcc gcccacaccc cccgaaaaaa caggggggcg
     3841 atggacggac aggcgcagtt gtccacctcg ccaaagatcc gcgctaaaag gattttttaa
     3901 ggctaaaaga caagagcgca ggaacccccc taaagggggc tattatctga taaggcttgt
     3961 ttcgatcacg gacgatcacg ctttaggtaa acgctcaccg tactggggga gatttgaaga
     4021 tcgtccgcta tatcgcggtt ggtgtacccc tgagccttaa gccgcagaac ctccggcaat
     4081 agatcggact tgtccttacc gctattgctc ggccttcccc ctcccttgga taccttgccg
     4141 cccttcgcac ctctccgggc ctgctcctct ctgaaccctg cggggcttag gtgctggtgc
     4201 gtccatttgg caatggactt ggccgtgtgc cggacttcgt ttgcggggag cggctgctcg
     4261 aactgggcgt tatatcctga tgcccggtca acacaagcgg ccaaccattc ggggtaatcc
     4321 ggccagccct gccggatcgc tttataggcc cacaggcgcg ttttctcgaa cagggtacag
     4381 tttcgcccaa gcccgtactc aggaagcgat ttgcggccat tgtaggagct cagatcgagg
     4441 taatcggata gccaggctaa atcgtagagc cggggttccc atacctgcac cagccagtgc
     4501 tcatgcaggg ggttcttgca gatcagcccg gagtagccca tatccgcccc taatttctcc
     4561 cggagcgcgg cctcgatggc ggcggcatac cgcagagggg ctgcatttcc atccggggca
     4621 gtgcggatcg gcgtatccag tccgtagatc agatgcgcgt ggccgttggc cttgttcgtg
     4681 acggtaatgt taggggctgg agcgcctacg tcatcccaag ataacgtagc ggctgcatgg
     4741 tctacgtcaa aaacgatcca gtggcggtgc gttggcccgt tcggctggat gtaacgcgca
     4801 ccaagggcgc gggcaacatc cgcaatccgt aggcccgttg taagctcgtc ggaatagtag
     4861 ggtttccggg gcaggcgctc ccgaaacagc tcaagctgtg cgcactttct caagcaccac
     4921 cgcgcttatt ggcggcgtgg ggttgtttgg catgatccat gtgatagact tctcttgtga
     4981 ttcgtcacgg cccccgtttt tcgcagctcc gccaagatgc aagcgataac gggggtttgt
     5041 cttttctgga caatacgtta cagcaggcac atcctagaga gcaacgttag ttgcatgtaa
     5101 cctttcaccc tggaacatat ttccacctcc ttctgcttct gcgctgtttt gaattgcttg
     5161 atctacgcct ctaactaggt cgatccttgg gattgagtgg caccattgtc agtgcaagaa
     5221 tactgatcca tataagtctc tctagtcgga caacaccaag tgttgaagag atcaaaaatc
     5281 aacctatatc ggaggattca tgtctgacat tgacagatgc ccccatgaaa gcaaagcgaa
     5341 tgcggtccca aagcgcctct gtagaaacga atttgagcga ggcatttgat gccatcgtct
     5401 gcgtcccaag cgccggcaag gacggcctgg ttgacctata gtaaaccggt agatgaaaat
     5461 gatggagaac caatatcagc gccttcttgg actttttcgt caaacgcttt agcagccaag
     5521 aaagcctaca atccttgatg ggctaggcac tttatcgcag cggcattcac ctttactgac
     5581 atcgccactc ctttattcac acccccatgt tgagtgacca tggccattga gataacaaaa
     5641 aagcctagca aattggctag gctttttacg tttaggaatg tgatgctaat gctcaggctg
     5701 aaagttaacg cgcggagctt aagtcgatta ggcctgaccg attaagtatg agccattaac
     5761 tacaagcgca tcgagcatca gcattttgtc catatatctt tacagcttat atgacggcta
     5821 tttcacacaa atacgcgcta accacttcta gggaataatt ttctcctgtt tgagcacttc
     5881 ttttgtgatg gcttggcgca gccctaaacc atccgatgtg ggcatatcca tattcatcgc
     5941 aaaaaaccac acattatcat caagttcaac ccaaccaacc caccagccaa tcttaggttc
     6001 gatactagtc gagtatcccg ttttagcccg aataatatag tcgccattgg cttcggtcag
     6061 catggcttgt ttcacgatgc gctgactacg ctcagaaacg tgcagcttgt tgtgatacag
     6121 cttgcgtaaa aaagcgattt g
//
