LOCUS       NZ_OY856406             6141 bp    DNA     circular CON 15-DEC-2023
DEFINITION  Klebsiella pneumoniae strain KP1462023BGR isolate KP1462023 plasmid
            P_KP1462023_3, complete sequence.
ACCESSION   NZ_OY856406
VERSION     NZ_OY856406.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA114785894
            Assembly: GCF_963693505.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Ivanov,I., Teneva,D. and Stoikov,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-DEC-2023) NCIPD, CMAR, Yanko Sakazov 26 Sofia,
            Bulgaria
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/15/2023 00:13:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,600
            CDSs (total)                      :: 5,482
            Genes (coding)                    :: 5,275
            CDSs (with protein)               :: 5,275
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 207
            CDSs (without protein)            :: 207
            Pseudo Genes (ambiguous residues) :: 0 of 207
            Pseudo Genes (frameshifted)       :: 122 of 207
            Pseudo Genes (incomplete)         :: 93 of 207
            Pseudo Genes (internal stop)      :: 25 of 207
            Pseudo Genes (multiple problems)  :: 27 of 207
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OY856406.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6141
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP1462023BGR"
                     /isolate="KP1462023"
                     /isolation_source="human urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="P_KP1462023_3"
                     /geo_loc_name="Bulgaria"
                     /lat_lon="43.225887 N 27.936721 E"
                     /collection_date="2023-01-17"
     gene            285..1232
                     /locus_tag="U5A18_RS27900"
                     /old_locus_tag="KP1462023_27675"
     CDS             285..1232
                     /locus_tag="U5A18_RS27900"
                     /old_locus_tag="KP1462023_27675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_015060053.1"
                     /translation="MRKCAQLELFRERLPRKPYYSDELTTGLRIADVARALGARYIQPN
                     GPTHRHWIVFDVDHAAATLSWDDVGAPAPNITVTNKANGHAHLIYGLDTPIRTAPDGNA
                     APLRYAAAIEAALREKLGADMGYSGLICKNPLHEHWLVQVWEPRLYDLAWLSDYLDLSS
                     YNGRKSLPEYGLGRNCTLFEKTRLWAYKAIRQGWPDYPEWLAACVDRASGYNAQFEQPL
                     PANEVRHTAKSIAKWTHQHLSPAGFREEQARRGAKGGKVSKGGGRPSNSGKDKSDLLPE
                     VLRLKAQGYTNRDIADDLQISPSTVSVYLKRDRP"
                     /name="replication initiation protein"
     gene            1640..2032
                     /locus_tag="U5A18_RS27905"
     CDS             1640..2032
                     /locus_tag="U5A18_RS27905"
                     /inference="COORDINATES: protein motif:HMM:NF037437.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin VbhA family protein"
                     /protein_id="WP_043907050.1"
                     /translation="MSTTQIEKDSRRKAVNGVISSFQLEGEAITDEFKILLEDYINGKI
                     STDEVLAMVSDEPTTTEYDYEITPRTLGLGGGWNLRLLENGEEVGGGVFPLPEHCDFRD
                     EKALQTLLDSLYEDALAEASAWLASR"
                     /name="antitoxin VbhA family protein"
     gene            2014..2352
                     /locus_tag="U5A18_RS27910"
                     /old_locus_tag="KP1462023_27685"
     CDS             2014..2352
                     /locus_tag="U5A18_RS27910"
                     /old_locus_tag="KP1462023_27685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_043907051.1"
                     /translation="MAGQPLKRLRSIKIRVSDAELERLRELCPKAQLAEWMREQCLGVA
                     QPQRRTPAPTVDPALLRQLAGMGNNLNQIARRVNSGEWGPLDRLRIIAELSAIGRELEE
                     LHHDHQIP"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            2333..3787
                     /locus_tag="U5A18_RS27915"
     CDS             2333..3787
                     /locus_tag="U5A18_RS27915"
                     /inference="COORDINATES: protein motif:HMM:NF015397.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_064996073.1"
                     /translation="MIIKFHNRGVGRGSGPVGYLLGRDGNREGATLDRGNPAVIEALID
                     SSPYAKKYTSGVLSFAEADLPRATKDKLMSDFEKALLPGLEGNQYAVLWVEHRDKGRLE
                     LNFVVPNIELQSGKRLQPYFHKADNPRLDAWRTVVNGELKLHDPDDPLNRQAVITPKDL
                     PRGHKEAAQAITDGLLRMAGAGEIQSRDDVRKALQGAGFSVVRETKNSLSIADPDGGRN
                     IRLKGVLYEQDFRHGEGLRAELEAAGQRYREASDRRIHEARESYLRGVEIKRGENERRY
                     CRAQPENGLAVAQNVDLDAGQHRPVLERNERDPLVSGGIDSGAASHSPSLGREGRQAKA
                     DPVREEIGAPLRADLRPQSNRLGEGYLLDRAEGVLNDGIGAGIALRVRGFAERIRAAAQ
                     GMAGKLRELGEHVREHQTRGRDQQGSSRAIDEAGERLNAASGRLEQAAGGLDRASQQVA
                     KEREHRLLKALDRGWERGDRSRGFER"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(4069..4350)
                     /locus_tag="U5A18_RS27920"
     CDS             complement(4069..4350)
                     /locus_tag="U5A18_RS27920"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_043907053.1"
                     /translation="MGFFNLSKALEEVSDAFGAKETAIASAKLLGKGVVNLAHFAATTG
                     LDSVVKQTSNKVLNSESSTEEQREQAKKSAAWADARIAARNKAENTED"
                     /name="hypothetical protein"
     gene            4694..5491
                     /locus_tag="U5A18_RS27925"
                     /old_locus_tag="KP1462023_27700"
     CDS             4694..5491
                     /locus_tag="U5A18_RS27925"
                     /old_locus_tag="KP1462023_27700"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011071128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-48 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-232"
                     /protein_id="WP_043907054.1"
                     /translation="MRVLALSAVFLVASIIGMPAVAKEWQENKSWNAHFTEHKSQGVVV
                     LWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIAA
                     WNRDHDLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIR
                     ISATQQIAFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTSIEPKIGWW
                     VGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP"
                     /name="OXA-48 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-232"
     gene            complement(5898..>6050)
                     /locus_tag="U5A18_RS27930"
                     /pseudo=""
     CDS             complement(5898..>6050)
                     /locus_tag="U5A18_RS27930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015059985.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EreA family erythromycin esterase"
                     /name="EreA family erythromycin esterase"
     ARG             4695..5488
                     /name="blaOXA-232"
                     /gene="blaOXA-232"
                     /gene_name="OXA-48 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-232"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          298..1219
                     /name="rep_cluster_1195"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="81.974"
                     /coverage="98.0"
                     /evalue="0.0"
     Typing          2334..3784
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.554"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ctcaatccca aggatcgacc tagttagagg cgtagatcaa gcaattcaaa acagcgcaga
       61 agcagaagga ggtggaaata tgttccaggg tgaaaggtta catgcaacta acgttgctct
      121 ctaggatgtg cctgctgtaa cgtattgtcc agaaaagaca aacccccgtt atcgcttgca
      181 tcttggcgga gctgcgaaaa acgggggccg tgacgaatca caagagaagt ctatcacatg
      241 gatcatgcca aacaacccca cgccgccaat aagcgcggtg gtgcttgaga aagtgcgcac
      301 agcttgagct gtttcgggag cgcctgcccc ggaaacccta ctattccgac gagcttacaa
      361 cgggcctacg gattgcggat gttgcccgcg cccttggtgc gcgttacatc cagccgaacg
      421 ggccaacgca ccgccactgg atcgtttttg acgtagacca tgcagccgct acgttatctt
      481 gggatgacgt aggcgctcca gcccctaaca ttaccgtcac gaacaaggcc aacggccacg
      541 cgcatctgat ctacggactg gatacgccga tccgcactgc cccggatgga aatgcagccc
      601 ctctgcggta tgccgccgcc atcgaggccg cgctccggga gaaattaggg gcggatatgg
      661 gctactccgg gctgatctgc aagaaccccc tgcatgagca ctggctggtg caggtatggg
      721 aaccccggct ctacgattta gcctggctat ccgattacct cgatctgagc tcctacaatg
      781 gccgcaaatc gcttcctgag tacgggcttg ggcgaaactg taccctgttc gagaaaacgc
      841 gcctgtgggc ctataaagcg atccggcagg gctggccgga ttaccccgaa tggttggccg
      901 cttgtgttga ccgggcatca ggatataacg cccagttcga gcagccgctc cccgcaaacg
      961 aagtccggca cacggccaag tccattgcca aatggacgca ccagcaccta agccccgcag
     1021 ggttcagaga ggagcaggcc cggagaggtg cgaagggcgg caaggtatcc aagggagggg
     1081 gaaggccgag caatagcggt aaggacaagt ccgatctatt gccggaggtt ctgcggctta
     1141 aggctcaggg gtacaccaac cgcgatatag cggacgatct tcaaatctcc cccagtacgg
     1201 tgagcgttta cctaaagcgt gatcgtccgt gatcgaaaca agccttatca gataatagcc
     1261 ccctttaggg gggttcctgc gctcttgtct tttagcctta aaaaatcctt ttagcgcgga
     1321 tctttggcga ggtggacaac tgcgcctgtc cgtccatcgc ccccctgttt tttcgggggg
     1381 tgtgggcggc agcagttatc cacggagccg ctctttccct tgatcttgct ctagggcttg
     1441 cagtatcccg cccatggttg aataatgtac taagcaaggc tacacagagg cccctctacc
     1501 tgcttcgcgg tctcgggcct ctgtggcctt gttcaggggt gctacgcccc cccgaaaccc
     1561 cctgtggccc ccgctcgatc cgccccttcg ggacggtctg cgcggtggct tcttggctct
     1621 ggagaatgga cgaggcccta tgtcaacaac acagatagag aaagattcga gaaggaaggc
     1681 agtcaatggc gttatttcta gtttccaact agagggggag gccataaccg atgaattcaa
     1741 aattctactt gaagattata tcaatggaaa aatttccacc gatgaggtgt tagctatggt
     1801 aagtgacgaa cccacaacaa cggaatacga ctacgaaatc accccccgca ctctcggtct
     1861 tggcgggggc tggaatctgc gtttgctgga gaacggcgaa gaggtcggcg ggggtgtttt
     1921 ccccttgccg gagcactgcg attttcggga tgaaaaggcg ctccagacgc tactcgatag
     1981 cctctatgag gacgccttag cggaggcctc tgcatggctg gccagccgtt aaagcgcctc
     2041 cgctctatca agatccgggt ctcagatgcg gagcttgagc gcctgcggga gctctgcccc
     2101 aaggcccaac tggcggagtg gatgcgggag caatgtctcg gtgttgcgca accccagcgc
     2161 cgaacgccgg cgcctaccgt agatccggcg ctcttgcggc agttggccgg aatgggcaac
     2221 aacctgaacc agatcgcccg gcgcgttaat tccggggagt gggggccgtt ggatcggctg
     2281 cgcatcatag cggagctgtc cgctataggc cgcgagctgg aggaactgca ccatgatcat
     2341 caaattccat aaccgtgggg taggccgggg ctccgggcct gttggctact tgttgggccg
     2401 tgacgggaac cgggaaggcg caacgctcga ccggggcaac cctgcggtga ttgaagccct
     2461 gattgattcc agtccctacg ccaaaaaata cacctctggc gttctgtcgt ttgccgaggc
     2521 tgatttaccc agggcgacca aggacaagct gatgagcgac tttgaaaagg cgctcctgcc
     2581 cggactggag ggcaaccagt acgctgtttt gtgggtagag caccgcgaca aggggcggct
     2641 ggagctgaat tttgtagtcc cgaacatcga attgcagagc gggaagcggc tgcaacccta
     2701 cttccacaag gccgacaatc cgcgcctcga tgcgtggcga accgtggtaa acggggagct
     2761 gaaattgcac gacccggacg atccgttaaa ccgtcaggcc gttatcacgc caaaggattt
     2821 gccgaggggg cacaaggagg ccgctcaggc cattacagac gggcttttac gcatggccgg
     2881 agcaggggag atccagagcc gcgatgatgt gcgcaaagcc ttgcagggtg cgggtttcag
     2941 cgtggtacgc gaaaccaaaa acagcctgag cattgccgac ccggacgggg ggcggaacat
     3001 ccgattaaag ggggtgctgt atgagcaaga ttttagacat ggcgaaggac ttcgagcaga
     3061 gctcgaagca gcaggccaac gctatcgaga agcgtctgac cgaagaattc acgaggcacg
     3121 agaaagctat ctccggggcg ttgaaatcaa gcgaggagaa aatgagcgcc gctattgccg
     3181 agcacagcca gaaaatgggc tggctgttgc tcaaaacgtg gatctggatg ctggtcagca
     3241 tcgtcctgtt cttgagcgca acgagcggga tcctctggta tcagggggaa ttgatagcgg
     3301 agcggcaagc cactctccaa gccttggcag agaagggcgg caagctaaag ctgacccagt
     3361 gcgggaagaa attggagcac ctttgcgtgc agatctccga ccccaatcca accgtttggg
     3421 ggaaggatac ctattggatc gtgccgaagg ggtactaaat gacgggattg gagcgggaat
     3481 tgctctgcgc gttcgaggct ttgcagagcg catacgagca gcagcacaag gcatggcagg
     3541 aaagctacgc gaacttggcg agcatgtacg agagcaccaa acaagaggcc gagatcagca
     3601 gggcagcagc agagcgattg acgaggcagg tgaacggctt aacgcagcaa gtggacggct
     3661 tgagcaagca gctggagggc ttgaccgggc tagtcagcaa gttgcaaaag aaagggaaca
     3721 caggctcctg aaggcactgg atcgaggctg ggagcgtgga gacagatcgc gaggctttga
     3781 gcgttgacgg aacaaaacgg ccgtcagtta taaaaaaagg aaagtgctat cactttcctt
     3841 ttatcggcgg gaattatcgt tgagttcttc tatgccattt ttcatagtag taactgtaat
     3901 cttcatctct accaccagat tcaatccagt catcatactc agggctattt ttgaaatctg
     3961 aatcagacat gctaactcct tgttattagt tggcttctat ggaagctagc gcaccgtgaa
     4021 gttatgatca acgatgtagt ccacatcatt gtcgaaatgt gcgttcagct agtcttcggt
     4081 gttttctgct ttatttctag cggcgattct cgcgtctgcc catgcggcag actttttagc
     4141 ctgttctcgt tgttcttcgg ttgaagactc gctgttgaga actttgttgc tcgtttgttt
     4201 gaccaccgaa tccaaacctg ttgttgctgc aaaatgagct aggttaacaa ctcccttacc
     4261 taacaacttg gcactagcga ttgcggtttc tttagcccca aaagcatcag acacctcctc
     4321 aagcgcttta gataggttaa aaaatcccat actcccccta agaatatcat caataaaatt
     4381 gagtgttgct ctgtggataa cttgcagagt ttattaagta tcattgcagc aaagatgaaa
     4441 tcaatgattt atcaaaaatg attgaaaggt ggttgtaaat aatgttacaa tgtgtgagaa
     4501 gcagtctaaa ttcttcgtga aatagtgatt tttgaagcta ataaaaaaca cacgtggaat
     4561 ttaggtaata gttaaagctt gtgcctgatt gttgccacaa ttggtcagca gtttgctagg
     4621 gaatgagagg gcagagaatg ataagcttag cacttaattt gtatggatat attgcattaa
     4681 gcaaggggac gttatgcgtg tattagcctt atcggctgtg tttttggtgg catcgattat
     4741 cggaatgcca gcggtagcaa aggaatggca agaaaacaaa agttggaatg ctcactttac
     4801 tgaacataaa tcacagggcg tagttgtgct ctggaatgag aataagcagc aaggatttac
     4861 caataatctt aaacgggcga accaagcatt tttacccgca tctaccttta aaattcccaa
     4921 tagcttgatc gccctcgatt tgggcgtggt taaggatgaa caccaagtct ttaagtggga
     4981 tggacagacg cgtgatatcg ccgcttggaa tcgtgaccat gacttaatta ccgcgatgaa
     5041 gtactcagtt gtgcctgttt atcaagaatt tgcccgccaa attggtgagg cacgtatgag
     5101 taaaatgctg cacgccttcg attatggcaa tgaggatatc tcgggcaatg tagacagttt
     5161 ttggctcgat ggtggtattc gcatttcggc tacccagcaa atcgcttttt tacgcaagct
     5221 gtatcacaac aagctgcacg tttctgagcg tagtcagcgc atcgtgaaac aagccatgct
     5281 gaccgaagcc aatggcgact atattattcg ggctaaaacg ggatactcga ctagtatcga
     5341 acctaagatt ggctggtggg ttggttgggt tgaacttgat gataatgtgt ggttttttgc
     5401 gatgaatatg gatatgccca catcggatgg tttagggctg cgccaagcca tcacaaaaga
     5461 agtgctcaaa caggagaaaa ttattcccta gaagtggtta gcgcgtattt gtgtgaaata
     5521 gccgtcatat aagctgtaaa gatatatgga caaaatgctg atgctcgatg cgcttgtagt
     5581 taatggctca tacttaatcg gtcaggccta atcgacttaa gctccgcgcg ttaactttca
     5641 gcctgagcat tagcatcaca ttcctaaacg taaaaagcct agccaatttg ctaggctttt
     5701 ttgttatctc aatggccatg gtcactcaac atgggggtgt gaataaagga gtggcgatgt
     5761 cagtaaaggt gaatgccgct gcgataaagt gcctagccca tcaaggattg taggctttct
     5821 tggctgctaa agcgtttgac gaaaaagtcc aagaaggcgc tgatattggt tctccatcat
     5881 tttcatctac cggtttacta taggtcaacc aggccgtcct tgccggcgct tgggacgcag
     5941 acgatggcat caaatgcctc gctcaaattc gtttctacag aggcgctttg ggaccgcatt
     6001 cgctttgctt tcatgggggc atctgtcaat gtcagacatg aatcctccga tataggttga
     6061 tttttgatct cttcaacact tggtgttgtc cgactagaga gacttatatg gatcagtatt
     6121 cttgcactga caatggtgcc a
//
