LOCUS       NZ_OY725782             9027 bp    DNA     circular CON 06-DEC-2023
DEFINITION  Parabacteroides distasonis strain Parabacteroides distasonis
            TSDC17.2-1.1 plasmid 37, complete sequence.
ACCESSION   NZ_OY725782
VERSION     NZ_OY725782.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA114266242
            Sequence Read Archive: ERR11836198, ERR11836210
            Assembly: GCF_963360645.1
KEYWORDS    RefSeq.
SOURCE      Parabacteroides distasonis
  ORGANISM  Parabacteroides distasonis
            Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
            Parabacteroides.
REFERENCE   1
  AUTHORS   Beller W,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-AUG-2023) WASHINGTON UNIVERSITY CENTER FOR GENOME
            SCIENCES, Jeffrey I Gordon Lab, 4523 Clayton Avenue, MSC
            8510-41-4209, St. Louis, MO 63110, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/06/2023 16:00:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,487
            CDSs (total)                      :: 4,412
            Genes (coding)                    :: 4,304
            CDSs (with protein)               :: 4,304
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 32 of 108
            Pseudo Genes (incomplete)         :: 69 of 108
            Pseudo Genes (internal stop)      :: 22 of 108
            Pseudo Genes (multiple problems)  :: 13 of 108
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OY725782.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9027
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /strain="Parabacteroides distasonis TSDC17.2-1.1"
                     /db_xref="taxon:823"
                     /plasmid="37"
                     /geo_loc_name="USA"
                     /collection_date="2021-09"
     gene            complement(127..2088)
                     /locus_tag="UNS60_RS16670"
                     /old_locus_tag="PDTSDC17_04471"
     CDS             complement(127..2088)
                     /locus_tag="UNS60_RS16670"
                     /old_locus_tag="PDTSDC17_04471"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_214504925.1"
                     /translation="MKRLIPKSRFSRRPTTVDSVKHRVKISGTDKTNIPLLSRCQNAWE
                     NLSDFRATRLRNFRYVFGDQWGDIVVDKDGERMKERDRIARRTGGVALQNNHLFKIVNT
                     LAGLYAKTATLPVCFARQKDADTKSQMMTDALQTNWENNLMKDVLTSEMIEFICGGCAV
                     VTEEWSSHDDIEDSYTYVVNPSYFFYESKANDPRHWDDSLIGEIRDYTLGELASVLAES
                     EYDYRQLEEIYSPWLNRMENLGTQQTDRFMDESFDTPPAADLCRTYHVWTLENKPRYRC
                     VDIMDTDDPIYRIELSDLPVIKRENEDRMRMGISQGLPPEEVPLIEYTYIIDQYWHFQM
                     LSPDGRVLTEYDTPYEYKSHPYVYKLHYLVNGRTVPFISVIIDQQRYINRLIMLNDLAI
                     QSAVKGVKMIPKDSVPDGMSNREFAEQFVEIGSFIFYEPSKSGNKPEVITSNSTNIGTT
                     ELLQLQLSFINDITSVSEALQGKTPSGSTAASRYAMETQNSTTSIATLLTKFSTFEAEI
                     ARKKMKTIHQYYQSPRNISMERSAGYATYNEYDPKTVQDIDFKVNIKESAESPVARMML
                     NDLVKELWMAGAISAEQMLSLSYYPGSDQILQSIQSNKQAVEQGGNIQAVPADQMNAIN
                     GQVNQDALNKARQALMSA"
                     /name="hypothetical protein"
     gene            2204..2647
                     /locus_tag="UNS60_RS16675"
                     /old_locus_tag="PDTSDC17_04472"
     CDS             2204..2647
                     /locus_tag="UNS60_RS16675"
                     /old_locus_tag="PDTSDC17_04472"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_214504926.1"
                     /translation="MTYEFEYIKAINKCEMLSSFEGRDLFGDSGESLYLKIKITEQDRP
                     LIRTYLEQAARSLEEGMSKIITSSAYSEEGFVWEVRTEDTRWNVNRKLDENLLDALVGY
                     SMMSWLSDRKPDRIGVYKSLWEDMSVMCVKNIYRKNPPLLKKA"
                     /name="hypothetical protein"
     gene            2649..3176
                     /locus_tag="UNS60_RS16680"
                     /old_locus_tag="PDTSDC17_04473"
     CDS             2649..3176
                     /locus_tag="UNS60_RS16680"
                     /old_locus_tag="PDTSDC17_04473"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_214504927.1"
                     /translation="MDINLGWTYLKHDIDQWTWRLGDMRKEDPGKRFSSQSDDNEADDT
                     FIRRKIEEAVATLRVSLSGILEDIPGDSDDSLDTDAVNWVLRMKDRRGGYDSESLATLA
                     HKYVVWFVLWNWCLIYFEELAGKLEEELKGIASMIEETAYSRKAPRKCKRKPFKDIDDV
                     IVDDVIIETGEI"
                     /name="hypothetical protein"
     gene            3173..3688
                     /locus_tag="UNS60_RS16685"
                     /old_locus_tag="PDTSDC17_04474"
     CDS             3173..3688
                     /locus_tag="UNS60_RS16685"
                     /old_locus_tag="PDTSDC17_04474"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_214504928.1"
                     /translation="MRDRKIIQPRVDMRGFELTITLLRCEIEYDVDFETWKVGDVSGLP
                     GKERAGLETSEETADWMFRQVNDALSEATGHLRAFSPWVQSRAVTDEVKDDREWIINLV
                     MERGWRGDPRRLAVYIHRFVVDSVLFFWYRMVDPSRVQMYASQKEVDRRNIINEARETQ
                     VKDVYFRL"
                     /name="hypothetical protein"
     gene            3692..3982
                     /locus_tag="UNS60_RS16690"
                     /old_locus_tag="PDTSDC17_04475"
     CDS             3692..3982
                     /locus_tag="UNS60_RS16690"
                     /old_locus_tag="PDTSDC17_04475"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_057319723.1"
                     /translation="MGKGFENGHMKMGGREKGTRNKNTEIKNFFRDFVIDNQEEFKKAF
                     LKLKDKDKCAVYLKASEFVVPKVSSIKFEDAKNTNSAIELLKVAASYKQKK"
                     /name="hypothetical protein"
     gene            complement(4013..6559)
                     /locus_tag="UNS60_RS16695"
                     /old_locus_tag="PDTSDC17_04476"
     CDS             complement(4013..6559)
                     /locus_tag="UNS60_RS16695"
                     /old_locus_tag="PDTSDC17_04476"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_214504929.1"
                     /translation="MEQQDISLSYGIHRSPSIGNEGELSECVNLIPKNGELVNIQPPKE
                     LGITLPEGSVLMYVHRTKDFLHYIFFQTNVLRYADTDGTTHLIGANQYDKIPKAITSIG
                     NTLIVISEDPIRYLLWDGEFYKELGDKPPFPILSFGLVGSLDKTEQLSVSVDPPYDGAF
                     TEDQLSTISNSVMGYVSKFIRERSVDRGMFIYPFFIRYAYRLYDGTSYMQSAPILMIPS
                     SGVTPHVPFTIDVDTDDFDAKIIVNFIISSVVCSINYKVSGMGNQREWWKDIVKSLDIF
                     ITPPIYTFDYYGEINGAQKISDDNGFGVYSIGGGYYNRHTFEGALSIALPGSGYTDQLV
                     LPGKAMDNKVPDNSLFYKVASIAYEDLCSYNGGERRSLTLEDNVLESLQNREQLVDADG
                     YQNLDWLIPDYSYTYNQRLNIANIKRILFDGYPPESMVTYNDGSSTLSIKVFIREGEKD
                     IVVQTSSSYNLGINLHYLYYPNANAYKMVITRNSDGYQAIVTLSPHNTLNGAYYFDSYA
                     PIIFKPGSDSTPISTDKSVNMPNKIYTSEVNNPFYFPLAGINTVGTGEIVGIRSTTKAL
                     SQGQFGQFPLYAFSSDGIWALQLSDAGLYSSIQPISRDVCNNPDSITQLDSSIVFSTER
                     GLKLLQGSDISLLSSSLEGANIDETFFNVNPDFSDLFIPDTETFVETLRACKIAYDYTN
                     SLLHIYPKGTRKHYVYSLDTGEFSTFVGEEVKAMAQDYPSSVVQIGNALYSLEKYISED
                     TRKGIAITRALTLGDPFSLKVLVDLRTLGLRKDESSKIKIAVFVSADRKNWSRLKSLRQ
                     RAFKYYRLVYFSNLYDLDTLSGTRVRFETRRDWRMR"
                     /name="hypothetical protein"
     gene            complement(6647..7471)
                     /locus_tag="UNS60_RS16700"
                     /old_locus_tag="PDTSDC17_04477"
     CDS             complement(6647..7471)
                     /locus_tag="UNS60_RS16700"
                     /old_locus_tag="PDTSDC17_04477"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_214504930.1"
                     /translation="MRDKPFYELLSRIDDDSLLANFFNKVLGNLDMARIISAPRTFRHK
                     DDENSRYCIDLFYDTCLWEMYLHQSIYKLRGWIKTLDEYLTEFGGSWKYYASSKRIESV
                     NEYGGDDDDYNEDGSVKVMDIPNDRLEPYSVIRELVCDDWIDIVQETIPKDLERLYGCL
                     QAEANLSIADFFKDKMGVDIPMYQKDDNGNMVKMGFADKVLHKAAEQNNSEVMGSYVLL
                     ACYCMHDLVSAIKSLNPFEDNVEALTSVRNDSMRFLSMSFSNMDVVKKYMSS"
                     /name="hypothetical protein"
     gene            complement(7800..8105)
                     /locus_tag="UNS60_RS16705"
                     /old_locus_tag="PDTSDC17_04479"
     CDS             complement(7800..8105)
                     /locus_tag="UNS60_RS16705"
                     /old_locus_tag="PDTSDC17_04479"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_214504931.1"
                     /translation="MKQIDIEVSTTISMTYDPESEEFKSALESYRDAIEDGASEEDMLR
                     QIAWYITAFGTENMIEGIGYVSVDGEKNGDPEDWCGVDIVNSLNINDTPDFQTAII"
                     /name="hypothetical protein"
     gene            complement(8153..8395)
                     /locus_tag="UNS60_RS16710"
                     /old_locus_tag="PDTSDC17_04480"
     CDS             complement(8153..8395)
                     /locus_tag="UNS60_RS16710"
                     /old_locus_tag="PDTSDC17_04480"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_320643408.1"
                     /translation="METKICRKCGKELSIDNFYKDRSAEDGLRCYCKACIKAYNASKKT
                     DTERRRGGIDESVHQSGSGKIQAKGAYRGIEGQRV"
                     /name="hypothetical protein"
     gene            complement(8641..8961)
                     /locus_tag="UNS60_RS16715"
                     /old_locus_tag="PDTSDC17_04481"
     CDS             complement(8641..8961)
                     /locus_tag="UNS60_RS16715"
                     /old_locus_tag="PDTSDC17_04481"
                     /inference="COORDINATES: protein motif:HMM:NF016343.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF551 domain-containing protein"
                     /protein_id="WP_320643409.1"
                     /translation="MRQTVEEAAHLFAESRSSGSAFPAYYQGFIAGAEWQAKQFPWISV
                     KDRLPPPGEEVLLFDKNSIRHLVLGWLRENKGYNKSMWALSNGHVDDEDITHWMRIPKN
                     HG"
                     /name="DUF551 domain-containing protein"
ORIGIN
        1 aatgcgaact agatcggttg gttgattctc tcgatttcga gcctgtcaac tttcatgagg
       61 tcaaggctag gataaggcac ctgatgagca tagaagggaa aagaaagtga tattacactt
      121 tatcctctat gctgacatca aggcttgtcg tgccttattg agcgcatctt gattaacctg
      181 tccgttgatt gcgttcattt gatcagctgg gacagcttgg atatttccac cttgctcaac
      241 cgcttgtttg ttggattgaa tggactgaag tatctggtct gatccggggt aatatgatag
      301 tgataacatt tgctccgcgg aaatggctcc ggccatccat aattccttca ccaagtcgtt
      361 taacatcatt ctcgctaccg gagattcagc ggattccttg atgttgacct tgaaatctat
      421 atcttggact gtcttcgggt catactcatt ataagtggca taacccgcgg atctctccat
      481 cgatatgttc cttggggatt gatagtattg atggatcgtt ttcatctttt tacgagcgat
      541 ctcggcctcg aacgtggaga acttggttag taacgtagcg atagatgtag tggagttctg
      601 tgtttccatg gcgtatctgc tagctgccgt tgatcccgac ggggttttcc cttgcaaggc
      661 ttccgacacg gacgttatat cgtttatgaa actcaattgt aattgcaata gctccgtggt
      721 accgatattg gtagagttcg atgttatgac ctccggtttg ttcccgctct tggacggctc
      781 gtaaaaaatg aatgatccga tctcaacgaa ttgctcggcg aactcacgat tggacatccc
      841 gtccggaacg gagtctttag ggatcatctt tactcccttt accgctgatt ggatagccaa
      901 gtcgttaagc atgatcagcc ggttgatgta tcgttgctga tctatgataa cggaaataaa
      961 aggaactgtc ctcccattca ccaaatagtg taacttataa acataggggt gagacttata
     1021 ctcataaggc gtgtcatact cggtaagtac acgtccgtcc ggtgatagca tctggaaatg
     1081 ccaatattga tctattatat aggtgtattc tatcaatggg acctcctccg gtggtaatcc
     1141 ctgagatatt cccatacgca tacgatcctc gttctctctc ttgataacag gaagatcgct
     1201 aagctctatc ctgtatatag gatcatcggt atccatgata tccacgcaac ggtatctagg
     1261 cttgttctcc agtgtccaaa catggtaggt ccggcacagg tcggcggcgg gaggcgtgtc
     1321 aaaagactcg tccatgaaac gatccgtctg ctgggttccc agattttcca tacgattgag
     1381 ccaaggtgag taaatctcct ccaattgcct gtaatcatac tcggactccg ctaataccga
     1441 ggccagctcg cctaatgtat agtcacggat ctccccgatc aaggaatcat cccagtgcct
     1501 tggatcattg gctttcgact catagaagaa ataggaaggg ttgaccacgt aggtgtagct
     1561 gtcctctata tcgtcatggc tagaccattc ctccgttacc acggcgcatc caccgcaaat
     1621 aaactctatc atctcagagg tgaggacatc tttcataagg ttattttccc agttggtctg
     1681 taaagcgtcc gtcatcatct gtgacttggt atccgcgtct ttctgccggg cgaaacatac
     1741 gggaagggta gcggtctttg cgtataaccc cgccaaagta tttacgatct tgaaaagatg
     1801 attgttctgc aaagcgaccc ctcccgtacg cctcgctatc ctatcgcgtt ccttcattct
     1861 ttccccgtcc ttgtccacca cgatatcacc ccattggtca ccgaacacgt aacggaaatt
     1921 acgaagacgg gtggccctga aatcgctaag gttttcccaa gcgttttggc acctagacag
     1981 taaaggtatg ttggtcttgt ccgtgcctga tatcttgacg cggtgcttga cgctatcaac
     2041 cgtcgtgggg cgtcgggaaa accgtgattt aggaataagt cgtttcatga ttgatctttt
     2101 taatcgcaaa taaatcgaat aaaagcactt ggttttgtca gaataaccaa aataacaaaa
     2161 taatcatacc taaagcccta tttttgccag aaaaggatca caaatgacat atgagtttga
     2221 atatataaag gcgataaata aatgcgaaat gctatccagc ttcgagggac gtgatctctt
     2281 cggggatagc ggggaaagcc tatatctaaa gataaagata acggaacagg acaggcctct
     2341 tataaggaca tatctggaac aagcggcaag gtcgctggag gaaggcatgt ccaaaatcat
     2401 aacctcttcc gcttactcgg aagaagggtt cgtatgggag gtcaggacgg aggatacacg
     2461 ttggaacgtc aacaggaaat tggacgagaa cctgttggac gctctggttg gttattccat
     2521 gatgagttgg ctttccgatc ggaagcctga taggataggg gtttataaat ctttgtggga
     2581 ggatatgtcc gtcatgtgcg tgaagaacat atacaggaag aatcccccgc tattaaaaaa
     2641 agcatgatat ggacataaat ctaggttgga catatttaaa gcatgacata gaccagtgga
     2701 cgtggaggct gggagatatg agaaaggagg atcccggtaa aagattctcc tcgcagtccg
     2761 atgataacga ggccgatgat acttttataa gacgcaagat agaggaggcg gtggcgacct
     2821 tgagggtatc cttgtccggt atcttggagg atatacccgg cgattcggat gactcattgg
     2881 atactgatgc cgtgaattgg gtgttgcgca tgaaggatcg tcgtggagga tatgatagcg
     2941 agtcattggc gaccttggcc cataaatacg tggtgtggtt cgtcctttgg aattggtgcc
     3001 tgatttactt tgaggaacta gccggaaagc tagaggagga gttaaagggt atagcgtcca
     3061 tgatagagga aaccgcctat tcaaggaaag ccccgcgaaa gtgcaagagg aagccgttta
     3121 aggatatcga tgatgtcatt gttgatgatg tcattataga aacaggagaa atatgagaga
     3181 caggaaaatc atacagccac gtgtcgatat gcgtggattt gagttaacga taacgctatt
     3241 gaggtgcgag attgagtatg acgtggattt cgagacatgg aaggttgggg atgtatcggg
     3301 ccttcccgga aaggaaagag ctgggctgga gacctcagag gaaacggcgg attggatgtt
     3361 tcgtcaagtg aatgatgcgt tgtcggaggc taccggccat ttacgggcgt tttcaccttg
     3421 ggttcagagc cgcgccgtaa cggacgaggt gaaggatgat agggaatgga tcataaactt
     3481 ggtgatggaa agaggatggc gtggggatcc gaggagattg gccgtttata tccaccgttt
     3541 cgtggttgat agcgtattat ttttttggta taggatggta gatccatcta gggtacagat
     3601 gtacgcctct caaaaggagg tggatagaag aaatatcata aacgaggcaa gggagacaca
     3661 ggttaaggat gtttatttca gattatagat catgggaaaa ggttttgaga atggtcacat
     3721 gaagatggga ggaagggaga agggaacccg gaataagaac acggagataa agaatttttt
     3781 ccgtgatttc gtaatcgaca atcaggaaga gttcaagaaa gctttcctca agttaaagga
     3841 taaggataaa tgcgctgttt atttaaaggc tagtgagttc gtggtaccaa aggtatcctc
     3901 tataaagttc gaggacgcta aaaacactaa ttccgctatt gagttgttga aggttgcggc
     3961 cagttacaag caaaaaaaat gacatatacc cccggctagg ccgaggggta ctttaacgca
     4021 tcctccaatc ccttctagtc tcgaatctta ctctggttcc tgataaagtg tctaaatcat
     4081 acaggtttga gaaataaacg agccgatagt atttaaaagc cctttgccta agagatttaa
     4141 gccgagacca atttttccta tccgcgctta cgaataccgc tatcttgatt tttgaggact
     4201 catcctttcg taaacccaac gtcctaagat cgactagtac cttcaaagag aaaggatctc
     4261 ctaacgtcaa ggcacgtgtg atcgctatgc cttttctggt atcttccgag atatattttt
     4321 ccagtgagta caaggcgtta cctatttgca ctaccgagct tggataatct tgcgccatgg
     4381 ccttgacctc ttcccctacg aaagtggaga attccccggt gtccaaagaa tatacataat
     4441 gctttctagt ccctttggga taaatatgca atagggaatt cgtataatca taggcaatct
     4501 tacaagctcg caatgtctct acgaaagttt ccgtgtccgg gatgaacaga tcgctaaaat
     4561 ccgggttgac attaaagaat gtctcatcaa tatttgctcc ttccaacgat gatgataaaa
     4621 ggctgatatc ggagccttgc aataatttaa ggccacgctc ggtactgaat actatcgagg
     4681 aatccagttg cgtgatacta tccggattat tgcaaacatc cctgcttata ggttggatgg
     4741 aggaatacaa tcccgcatcc gataattgca aggcccatat tccatcggaa gagaaagcgt
     4801 ataagggaaa ctgcccgaat tgcccttggg acagcgcttt cgtggtggat cggataccta
     4861 cgatctcacc ggttcccacc gtgtttattc ccgccaacgg gaaataaaac gggttattga
     4921 cctcggacgt atatatcttg tttggcatat tgaccgactt gtccgttgat attggtgtgc
     4981 tatcgctgcc cggtttaaat atgatcgggg cgtatgagtc gaaatagtaa gccccgttca
     5041 gcgtgttatg cggagagagg gtaacgatcg cttggtatcc gtccgaattc cgtgttatca
     5101 ccatcttgta tgcgttagcg ttggggtaat ataggtaatg caaattgata ccaaggttat
     5161 atgaggagga tgtttgaacg acgatatctt tttctccttc tcttatgaaa acctttatgc
     5221 tcaacgtgct gctaccgtcg ttgtacgtca ccatggactc cggaggataa ccatcaaata
     5281 gtatcctttt tatattagct atatttaacc gctggttata agtataggaa taatcaggta
     5341 ttagccaatc taaattctgg tacccgtctg cgtcaacaag ttgctctcga ttttgcaacg
     5401 attccagcac attatcttct aaagtgagag aacgtctttc acccccgtta taactgcaca
     5461 agtcctcata cgctatgctt gctactttgt aaaacaatga attatccggc accttattat
     5521 ccatggcctt tccgggtaag acgagttgat cggtataacc tgatcccggc agggctatgg
     5581 acaaggctcc ctcgaatgta tgcctattgt aatatcctcc acctatagag tacaccccga
     5641 aaccgttatc gtctgatatc ttttgtgccc cattaatctc cccataataa tcaaaggtgt
     5701 atattggcgg cgttatgaat atatcaaggc ttttaactat gtccttccac cattcccttt
     5761 gattccccat tccgctgact ttgtaattaa tggagcatac cactgaggat ataatgaagt
     5821 ttacaatgat ctttgcgtca aaatcgtctg tgtccacatc aatagtaaat ggaacgtgag
     5881 gagttactcc agacgatggt atcatcagta tcggggctga ttgcatgtaa gacgttccgt
     5941 catatagtct ataagcgtaa cgaataaaga acggatatat aaacatgcct ctatccacgc
     6001 ttctctccct gataaatttt gagacatatc ccatcacgga attactgata gttgatagtt
     6061 gatcttccgt aaaggctcca tcatagggag gatcaacgga tacggacaat tgttcggtct
     6121 tatccaatga tcctaccaat ccgaatgaca ggatagggaa ggggggctta tctcctaatt
     6181 ccttataaaa ctctccatcc caaagtaaat atcttatagg atcttcgctt attacaatta
     6241 aggtgtttcc tatggacgtg atagctttgg gtattttgtc atattggttc gctccaataa
     6301 gatgggtcgt tccgtccgta tccgcataac gtaaaacatt cgtctggaaa aagatatagt
     6361 gaaggaaatc ctttgtccga tgcacgtaca taagtaccga tccttccggg agggttatgc
     6421 ctaattcttt cggaggctgt atattcacca actcaccatt cttgggtatc aaatttacac
     6481 attctgataa ttccccctcg tttccgatag atggagaacg gtgtatcccg taggataatg
     6541 aaatatcttg ctgttccatt ttttgcgata aaattatatg atataagtaa taggttttga
     6601 catattgatc aaaacctatt gcatttagat ggccttgatg tgcctgttat gatgacatgt
     6661 atttttttac gacatccata ttactaaagg acatggatag aaaccgcatt gagtcattcc
     6721 ttacgctagt caatgcctcc acgttgtctt caaatggatt taacgatttt atggcggaga
     6781 caagatcatg catacaatag catgccaaca atacatacga tcccatgacc tctgaattgt
     6841 tttgttcagc ggctttatgc aatactttgt ctgcgaatcc catcttaacc atattgccat
     6901 tgtcatcttt ttgatacata ggtatatcaa ctcccatttt gtccttgaaa aaatccgcta
     6961 tggataaatt agcctctgct tgtaggcatc cgtatagcct ctccaaatct ttcgggatgg
     7021 tctcttgaac tatatcaatc caatcgtcac agactaactc ccttatgact gagtaaggct
     7081 caagcctgtc attgggaata tccatgactt tcacgcttcc atcctcgtta tagtcatcgt
     7141 catcgccgcc atattcatta acgctctcga tacgtttcga ggaagcgtaa tatttccagc
     7201 tcccaccaaa ctctgtcagg tattcatcca gtgtttttat ccatcccctc agtttgtata
     7261 tggattgatg aagatacatt tcccacaagc atgtatcata aaaaagatca atgcaatatc
     7321 ggctattttc atcatcttta tgacgaaaag tacggggtgc ggatatgatt cttgccatat
     7381 ccaaattccc taacacctta ttgaaaaagt tggccaataa actgtcatca tctatgcgtg
     7441 ataacagctc ataaaaaggt ttatctctca ttaggctgaa attttaaggt tatacaaatc
     7501 aaggatgaac ttcttctcgg cctccgtcca atacatatgc tggcgtgtct taatctcatg
     7561 atttcaattt atttatcatt taatgattat atagtccccg caatcttcaa tatactttat
     7621 tccggcacta tcaagagtat tctctatgtc cacttggcac aggcaagatt ccggtatgat
     7681 attgtcatac ccttccgctg ggatcatttt cgtgatttgc gggaaatgat cctctagttg
     7741 tttaggggat tgtatttcta catccccgtc gtaaataagt acgcacatgt tattagaggt
     7801 taaattatcg ctgtttgaaa atctggagta tcatttatat tgaggctatt cacgatatct
     7861 actccgcacc agtcttctgg atcaccattc ttttcaccat ccacagatac ataaccgata
     7921 ccctctatca tgttttctgt gccgaatgca gtgatgtacc atgctatctg ccggagcata
     7981 tcttcttcac tagcaccgtc ctctatcgca tctctataac tttcaagtgc agatttaaac
     8041 tcttctgatt ccggatcata ggtcatactg attgtagtac taacctctat atctatttgt
     8101 ttcatgattt tttaattata atgttattac ttgttcgtag gtgagcgtcc ccttataccc
     8161 tctggccttc aattcctcga taagctccct tggcttgaat tttgccagat ccggattggt
     8221 gaacactttc gtcaatcccc ccccttcttc tctctgtatc ggtcttctta gaggcgttat
     8281 aggcttttat acaagccttg cagtagcagc gaagcccatc ctccgctgat ctgtccttat
     8341 aaaagttatc tatcgacaat tccttgccac attttctaca tatcttagtc tccatgatta
     8401 gatgttttaa tttgtacttt gattgttcta ttcatgatct cttaattatg agccttccca
     8461 tgaaggctcg gttaatacta ttcatttttg ctacgtttct cgatcatata aatattttta
     8521 ccatcattta ccgtgaccag aaataactta tcgcaattta gacatttgca attatataac
     8581 ccacagagaa aagatccctt tatgtatcta gtcgaatgac agaatgggca ttttattgaa
     8641 ttatccatga tttttaggta ttctcatcca gtgtgtaatg tcttcatcat caacgtgacc
     8701 atttgacaaa gcccacatac ttttattata tcctttattc tctcttaacc agcctaagac
     8761 aagatgtctt atagaatttt tatcaaataa cagaacctct tctccgggtg gcggtagccg
     8821 atccttcacg cttatccacg ggaattgctt tgcctgccat tcggcacctg ctataaatcc
     8881 ctgataatac gccgggaatg cactaccgct actcctgctt tcagcgaata aatgagccgc
     8941 ttcttctact gtctgtctca tatcaatatc tctttccatg attttaaata atatttaaat
     9001 attgctaacc acacattgtt agtacac
//
