LOCUS       NZ_OX291797            12879 bp    DNA     circular CON 03-SEP-2023
DEFINITION  Serratia marcescens strain SJC1050 plasmid 2, complete sequence.
ACCESSION   NZ_OX291797
VERSION     NZ_OX291797.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA13201017
            Assembly: GCF_946415285.1
KEYWORDS    RefSeq.
SOURCE      Serratia marcescens
  ORGANISM  Serratia marcescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Serratia.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (11-AUG-2022) WELLCOME SANGER INSTITUTE, Pathogen
            Informatics, Wellcome Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/02/2023 07:45:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,246
            CDSs (total)                      :: 5,115
            Genes (coding)                    :: 5,043
            CDSs (with protein)               :: 5,043
            Genes (RNA)                       :: 131
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 19
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 28 of 73
            Pseudo Genes (incomplete)         :: 44 of 73
            Pseudo Genes (internal stop)      :: 15 of 73
            Pseudo Genes (multiple problems)  :: 11 of 73
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OX291797.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12879
                     /organism="Serratia marcescens"
                     /mol_type="genomic DNA"
                     /strain="SJC1050"
                     /serovar="NA"
                     /isolation_source="Bloodstream"
                     /db_xref="taxon:615"
                     /plasmid="2"
     gene            join(12798..12879,1..503)
                     /locus_tag="N4J75_RS26105"
     CDS             join(12798..12879,1..503)
                     /locus_tag="N4J75_RS26105"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351424.1"
                     /translation="MDITISDATYSRLAAQAKGFETPEQVINRLIDVVEIDHDTRPELF
                     FNPEGEADFKKALLKSKQAKVEMFKRDGSCETGVWNARAISEESSVRANIWSGYLRGWK
                     EKGIVRAVFTVQEVPDLPGAAESVQWNDYTISRTFSGGISVQRNGMPVTIVKPFLRDVA
                     HDLKISLLNSNGNEMNTRQLGAAIIKKLNNS"
                     /name="hypothetical protein"
     gene            complement(758..1216)
                     /locus_tag="N4J75_RS26110"
                     /old_locus_tag="SAMEA13201017_05182"
     CDS             complement(758..1216)
                     /locus_tag="N4J75_RS26110"
                     /old_locus_tag="SAMEA13201017_05182"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765952.1"
                     /translation="MKSKTELREAATARSLAVIATEMSEWSLDGFSHLKLPNFSAGERQ
                     QTLSGSVVVDRPPFDYEWAGTEKFNTLATRALQVKLPASRERNYAWLCGVERETLATAL
                     LVELFSVTGCVAFAGLGKVADLAFLTLDESEAGQIRAAMLQWLDGAAA"
                     /name="hypothetical protein"
     gene            complement(1442..2623)
                     /locus_tag="N4J75_RS26115"
                     /old_locus_tag="SAMEA13201017_05183"
     CDS             complement(1442..2623)
                     /locus_tag="N4J75_RS26115"
                     /old_locus_tag="SAMEA13201017_05183"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765953.1"
                     /translation="MAFDNSHLTDAGLFWRAVSAAGAPVDREDWLRLCSGIACWASLCG
                     EDGLAAIEAWSTRHNRGSAHHRSQYRHFLKLKGVTNPEAMAQVFLRFSGEVYWRLDSNR
                     TPPSTEQVAALAERKRRSIEAVARREDADRRKADKAAADAVRMLAKGDGNPAYTPYWRN
                     KTTIARRGGVSLPPLPADLRVGGLFRSFEPRAYWSRCLLVPAYRLTDDRQLVGDALEAI
                     CGVCSAGGKTGDKFSPAGTQKAGRFYPMPGFMDVLDTSPHAPYSPLFVCEGFATAVALH
                     HLTKGKVAVCAAFSIAGFGSCVASLRRFWPDVDVMLVPDHGEAYRLAHKAAYGDEREPV
                     PTIPGAAVVSFDGLDRFTPRDNLDWFDVLVEEGEDRARELLRYAVRHARLERR"
                     /name="hypothetical protein"
     gene            complement(2610..2819)
                     /locus_tag="N4J75_RS26120"
     CDS             complement(2610..2819)
                     /locus_tag="N4J75_RS26120"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765954.1"
                     /translation="MKKRIYTADLAALLNVSLRTLSRLSSRGIVPTPAGRSLRGGHYWL
                     AGDPVLKRFIADQRRPGRAPYGVR"
                     /name="hypothetical protein"
     gene            3175..4464
                     /locus_tag="N4J75_RS26125"
                     /old_locus_tag="SAMEA13201017_05184"
     CDS             3175..4464
                     /locus_tag="N4J75_RS26125"
                     /old_locus_tag="SAMEA13201017_05184"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_157698538.1"
                     /translation="MNDDNDTTEATQPSTEALKCVGAAERFPDIMPGVLFVTCPGGCSL
                     RVEACRQIYEQSHLDRTIENPHLECHRCPTGLALWVGTEQPPDAPLTTPADTRKLCPRC
                     SRKDNRLIAPNKPGSSLCVSCWNREREATIGANARGRVNRTPPFVSPFLIGIGDGWQVW
                     YGIHQGEALVRAMRANPGARFHDRRPGPVGQTRRDGFVYYCPEHREPLRWNGGDGHAGE
                     VELACPRCQPWAAPLSVAPTFQTVSFQTPHDAAHQYRNATLPDNAVWTSSVCADCKAAP
                     LVISKAPVKGKPRREIVVSCPSCDSSASARPGGRTWTDEHIAVPEFAQNETRSLAKIPV
                     ILPQGEQPQLLKRPGTGRGPGRPRKRIPLTLDRVPESRFNRLALSVLAAVGRWDYINDI
                     IRRIDRNRGDAATLIALADHIRTNRPERDL"
                     /name="hypothetical protein"
     gene            4461..5102
                     /locus_tag="N4J75_RS26130"
                     /old_locus_tag="SAMEA13201017_05185"
     CDS             4461..5102
                     /locus_tag="N4J75_RS26130"
                     /old_locus_tag="SAMEA13201017_05185"
                     /inference="COORDINATES: protein motif:HMM:NF016255.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_070559060.1"
                     /translation="MTETTRPILTIKRRNRTVYVPPEKAAKSEPQPAERTTSKAKVQPK
                     AKAPQKPAQKPTAAKPKKTPEQVAEGIRRQEENDRRQQDIAIANKSKKALANRVTKAFL
                     KEHWPDLLTRGVDRRPMAKGIIEQILTRGAELNMPPEADRKAVRRILGIVTGTSSYQQS
                     LIDQCMRYDLDGNPTEPATPEEAENAKARLTEIKAFRRKARQAKGEKKGA"
                     /name="ProQ/FINO family protein"
     gene            complement(5260..5616)
                     /locus_tag="N4J75_RS26135"
     CDS             complement(5260..5616)
                     /locus_tag="N4J75_RS26135"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559062.1"
                     /translation="MPRHLQGKTRMPLAGGCYSAGHRLALISLLPVLEARPGDRDDGER
                     SKLALYQESLIKAGQPHAFALHEPSLYRWGAYLKSRRARYLQETDAGVAAASDALDRHA
                     FGRAIGAVLGADDE"
                     /name="hypothetical protein"
     gene            complement(5622..6005)
                     /locus_tag="N4J75_RS26140"
                     /old_locus_tag="SAMEA13201017_05186"
     CDS             complement(5622..6005)
                     /locus_tag="N4J75_RS26140"
                     /old_locus_tag="SAMEA13201017_05186"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559064.1"
                     /translation="MSAFSMLCDRLRHEATLAKSTGAGDALAQVLETGGAAQTFAPIGA
                     PVASPTESVHRARAQSIQDAAFLTEMKQAGVAPADLVMLDGVLASSRGLPDASRAPAFA
                     AVRAQVQQQASLSPAARGINWDE"
                     /name="hypothetical protein"
     gene            complement(6006..6662)
                     /locus_tag="N4J75_RS26145"
                     /old_locus_tag="SAMEA13201017_05187"
     CDS             complement(6006..6662)
                     /locus_tag="N4J75_RS26145"
                     /old_locus_tag="SAMEA13201017_05187"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879883.1"
                     /translation="MTEIKTECPDATWLRTTLAEMASDHFPVYDLPCLSVDPNSSAQLT
                     ALDDRRVAREMRQAAADVETRRIDAARVVEGLRTEAERLRGLIADGKTALRAGETVSPD
                     AGVAAFLLPDIEAELVAAEAAEADVARERDALLQDADRRDAAAAIGLFNLAHAVRVQRI
                     EQLLKLAMDEATLLAESDAGRSLYRTVINPDRRLNQLFSTQGAIEILRRNRGMEA"
                     /name="hypothetical protein"
     gene            6922..7509
                     /locus_tag="N4J75_RS26150"
                     /old_locus_tag="SAMEA13201017_05188"
     CDS             6922..7509
                     /locus_tag="N4J75_RS26150"
                     /old_locus_tag="SAMEA13201017_05188"
                     /inference="COORDINATES: protein motif:HMM:NF012464.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_181654175.1"
                     /translation="MSKTYGYVRVSTDEQTSNSQRDAIIARFPTASILADDGISGTVPP
                     RERPALGILLNQILQEGDTLVIYAIDRIGRNARDALELVEELEKRKVTLVSIREGVDLS
                     SAVGQAVLGIMASFAQMERKLILERQAAGIEAAKSRGQKFGRPTKIGAKEAGEIVMRRA
                     MGVPIATIAKQLNLSRSAIYRHLEKVDAVAPE"
                     /name="recombinase family protein"
     gene            7620..7805
                     /locus_tag="N4J75_RS26155"
                     /old_locus_tag="SAMEA13201017_05189"
     CDS             7620..7805
                     /locus_tag="N4J75_RS26155"
                     /old_locus_tag="SAMEA13201017_05189"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879885.1"
                     /translation="MINQAATPRYPGLSIEHGEIRQFGKPRHCAANRKGQYQTTLRDSA
                     GRYQTVSIISLYAWEA"
                     /name="hypothetical protein"
     gene            7924..8169
                     /locus_tag="N4J75_RS26160"
                     /old_locus_tag="SAMEA13201017_05190"
     CDS             7924..8169
                     /locus_tag="N4J75_RS26160"
                     /old_locus_tag="SAMEA13201017_05190"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558916.1"
                     /translation="MAFENIPRRFQRWKVIMVPGAKSYESWDEMVTGENFSEETRMKTY
                     KKHRTKAIDRTVANQEYIHTMTEDGITVRYRLERWR"
                     /name="hypothetical protein"
     gene            8368..8835
                     /locus_tag="N4J75_RS26165"
                     /old_locus_tag="SAMEA13201017_05191"
     CDS             8368..8835
                     /locus_tag="N4J75_RS26165"
                     /old_locus_tag="SAMEA13201017_05191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324036.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_070559148.1"
                     /translation="MKKYTTEQKAQALRLLEQDGATAATVARTMGIPPRTVRDWAKART
                     DAPSNVLSIEEMRERAQRAVEATPQAAIRRLKNHFVQRQFELLQRHATDLQALRTASLQ
                     AMLEKDATMVKAISGLMTSLLKTQERERVIYEIKPGTEADIMREGMNRQQS"
                     /name="transposase"
     gene            complement(9481..10776)
                     /locus_tag="N4J75_RS26170"
                     /old_locus_tag="SAMEA13201017_05192"
     CDS             complement(9481..10776)
                     /locus_tag="N4J75_RS26170"
                     /old_locus_tag="SAMEA13201017_05192"
                     /inference="COORDINATES: protein motif:HMM:NF017116.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="WP_119879886.1"
                     /translation="MSQIDENSGTAADNVTPIAAAKVGRPSLQKKYPTTAFPVELEINY
                     RKGRYSSSLENVVAAMRCHSVTGIQLAFDEFFAEEGAFVNGQWYPLSDNLVTELRLRLA
                     AADFEKVTKDNARDAMFYVCDENKFDSAQRWLTAQEWDGKPRVSYFFERCFKCQGDPEY
                     LAAVSLYTWTALAGRVMNPGIKADMVPLLYGRQGARKSTGVRLMSPFPDSYSSFNLNDK
                     DDSLVRRMRGCLIGELEELRGLHGRDSESVKAFFSAAHDEWVPKFKEFKVRNPRRVVFI
                     GTTNNKQILNDSTGNRRYLPMNSGDVDCAAIEKNRSQLWAEALHLFNENGVMWEAAETL
                     ARKVHDEFRVEDPWEDEIAELLKLDVDDCDPTAFVPTKALFSQVGLMIGHTSNKQHQRM
                     AAIMSRLGYEVGRKRINGALVRGYFRRTQAVV"
                     /name="VapE domain-containing protein"
     gene            11304..11795
                     /locus_tag="N4J75_RS26175"
     CDS             11304..11795
                     /locus_tag="N4J75_RS26175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558888.1"
                     /translation="MREKTKTLTVRLPVSLIERIEQNAARTGATRTDAVIEALNAGLGT
                     KPEGMDTKLLAAIEALRAEVRALSVGGKPARQTAQQTAPQSAQQPARQIVPRGADPRFQ
                     AVSDEADQLIVSMTAENATLPAIASALNAAGHRTATGQEWNTSRVRDYRHKLRESGLLN
                     "
                     /name="hypothetical protein"
     gene            11860..12351
                     /locus_tag="N4J75_RS26180"
     CDS             11860..12351
                     /locus_tag="N4J75_RS26180"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351425.1"
                     /translation="MAIGDDAIRDAFYAFTQQAEEMDDKGLPQEVWETPCFTYLMTKKQ
                     FNQMKVVCQRNGWDIPASPAIPITWAMFRHVLSARNSKDKLSWQECAEILATAFSVQSN
                     VYVNRDYSEQTIVLNAVRRINVAGAGFFAMAIVDVSENNLAPVTAYHATEAKCKAIQRG
                     "
                     /name="hypothetical protein"
ORIGIN
        1 accgtctgat cgatgttgtt gaaatcgatc atgacacacg ccctgaactt ttttttaatc
       61 ctgaaggtga agcggatttt aaaaaagcgt tactaaaatc aaaacaggcc aaagtcgaaa
      121 tgtttaaaag ggatggttcc tgtgaaactg gagtatggaa tgctcgtgcg atttcagaag
      181 aatcatcagt tcgggcaaat atttggagtg ggtatttgcg tggatggaag gaaaaaggga
      241 ttgttcgtgc ggttttcact gtccaggagg ttcctgactt gccaggagcg gctgaaagtg
      301 tgcagtggaa tgattataca atcagtcgca cttttagtgg cggtatttca gttcaaagaa
      361 atggcatgcc tgtaactatt gtgaagccat ttctacgtga tgttgcgcat gatttaaaaa
      421 tatcattgct aaatagcaat ggaaatgaaa tgaatactcg gcagcttggc gcagcgatca
      481 taaagaagtt aaataactct taacatcgat gcttcacgca gaggagcgac ggctcaacgc
      541 cgccgccggt cagagttcta ctgcgacgaa tacgcaccat tcatagctgg cgaggcagaa
      601 cgcccgccac ctgtcatcag acgcccggtc aacacactcc agccataacc gcgccgcagc
      661 aaggtggtcg cagcgcaccg ggtcgccccg cagttccgtc gccatggcct cctcgatcag
      721 tcgcccttcc cactccagct gatcgaggat cgagccccta cgccgccgcc ccatcgagcc
      781 actgcagcat cgccgccctg atctgccccg cctcgctctc gtccagcgtc aggaacgcca
      841 gatcggcaac cttacccagc ccggcgaacg ccacgcagcc ggtgacggag aacagctcca
      901 cgaggagcgc cgtcgccagc gtctcccgtt caacgccgca caaccaggcg tagttacgct
      961 cacgcgatgc cggaagtttc acctgcagcg cacgggtggc cagagtgtta aatttctcgg
     1021 taccagccca ctcgtagtcg aacggcgggc gatcaaccac caccgacccg gacagcgtct
     1081 gctggcgttc cccagcggag aagttcggca gcttgaggtg ggagaaccca tcgagcgacc
     1141 actccgacat ttcagtggcg atcaccgcca gagagcgagc cgtcgcggcc tcgcgtagtt
     1201 cagtctttga tttcatgtgc cctcctttgg gctaaaaaaa aacccgacat caagacgagg
     1261 ccgggcttta tgctgctgtg agaaaccgat cgcaggatag cgtcacgacg gcagcgccgg
     1321 tgcgtcgctt tagtccgtct catcaaaaaa gcatcggtag tgtctcgaaa gtcgttcgct
     1381 aaaccagacg ccacgacggc aaaaaagatg tcccgaaagg cgcaccattc ggacacgcca
     1441 atcaacgccg ctcaagccgg gcatgacgaa ccgcgtagcg cagcagctca cgagcccgat
     1501 cttccccttc ctcaaccagc acgtcgaacc agtcgaggtt atcccggggc gtgaagcgat
     1561 cgaggccgtc gaacgacaca accgccgcgc ctggaattgt cgggaccggc tctcgctcat
     1621 cgccataggc cgctttatgc gccaggcggt acgcttcgcc gtgatccggt accagcatca
     1681 catcaacatc tggccagaac cggcgcagcg acgccacgca gctgccgaac ccggcaattg
     1741 agaacgccgc gcagactgcc accttgccct tcgtcagatg atgcagggca accgccgtgg
     1801 cgaacccctc acagacgaac agaggcgagt agggcgcatg tggtgaggta tcgagcacgt
     1861 ccataaagcc gggcatcgga tagaaccgtc ccgccttttg ggtacctgca ggggagaact
     1921 tgtcgccggt tttgccgcca gcagagcaga cgccgcagat ggcctccagc gcgtcgccaa
     1981 ccagctggcg atcatcggtc aggcgatagg caggaacaag cagacagcgc gaccagtacg
     2041 ccctcggttc gaacgagcgg aacaagccac ccacacgaag gtcagcgggg aggggcggga
     2101 ggctgacgcc accacgcctg gcgattgtgg tcttattgcg ccagtacggg gtataggccg
     2161 gattaccgtc gcctttcgcc agcatcctga ccgcatcagc cgcagcctta tcggccttgc
     2221 gccggtcggc atcttcgcgt ctggccaccg cctcgatcga tcggcgtttc cgttcagcaa
     2281 gagcagcaac ctgttcagtc gacggcggcg tgcgatttga gtcgagccgc cagtacacct
     2341 cgcctgagaa ccgcaggaat acttgcgcca tggcctcggg attggttacg cctttcagct
     2401 tcaggaagtg ccggtactgc gaccggtgat gcgcagatcc gcgattgtgg cgggtagacc
     2461 aggcctcgat agcagcaagc ccgtcctctc cgcagagaga tgcccagcat gcgatgccag
     2521 aacagaggcg cagccagtcc tcgcggtcaa ccggagcccc agccgcagag acggcacgcc
     2581 agaacaggcc agcgtcagtc aggtgagagt tatcgaacgc cataaggagc cctcccggga
     2641 cgacgctggt cggcaataaa gcgtttgagc acgggatccc cagccagcca gtaatgcccg
     2701 ccacgaaggg aacgccctgc cggagtcgga acgatccccc gcgaactcag gcgggagagc
     2761 gtgcgcagcg acacgttcag cagcgcagcg aggtcagcgg tatagattcg ttttttcatt
     2821 gggagtacca gataggtgcc cccctcagct taacgggcat cggggggcgg gagtgacgat
     2881 tatcgataaa gccgcccttg aggacttacc gcatagcggc aggacagcag cccttctcgc
     2941 ttactcgcac ctgccaagga cgaagcgcgc atcctcgttt acaaccccgc ctcgttgggg
     3001 aggagggaaa gcggcaccgg gcgatccggt ttcatgtttc ccaactgctc gtcaggaatc
     3061 agtaagacaa gcttaacaca attaacgcca aagtggcgtt ttttgtgaga tactaaaaaa
     3121 gacgcacagc cagtgctggc gaggtctggc gaccatttcg acgcaggggg agcagtgaac
     3181 gacgataacg acacgacaga agcgacgcag ccgtcaaccg aggcactgaa gtgcgtaggc
     3241 gctgcggagc ggttccccga catcatgccc ggcgttttgt tcgtcacctg ccccggcggg
     3301 tgctccctcc gggtcgaggc atgccgacag atttatgagc agagccacct cgatcgcacg
     3361 attgaaaacc cccacctcga gtgccaccgg tgccccactg gcctcgcgct ttgggtcggt
     3421 accgaacagc cccctgacgc accactgacc accccggcag acacccgtaa gctctgcccc
     3481 cgttgcagcc ggaaagacaa ccgcctgatc gcccccaata agcccggttc gagcctgtgc
     3541 gtctcctgct ggaaccgcga acgcgaagcc accatcggag ccaacgcacg cgggagagtc
     3601 aaccgcaccc caccgttcgt ctcgccgttc ctgatcggca tcggcgatgg ctggcaggtc
     3661 tggtacggca tccaccaggg cgaggcgctc gtccgcgcca tgcgagccaa cccgggcgca
     3721 cggttccacg atcgccgacc aggcccggtc gggcaaacac gccgcgacgg tttcgtgtac
     3781 tactgccccg aacaccgcga gcccctgcgc tggaacggtg gcgacgggca cgccggagag
     3841 gtggagcttg cttgtcccag gtgccagcca tgggcggcac ctctcagcgt cgcccccacg
     3901 tttcagacgg tcagcttcca gacaccgcat gacgccgcgc accagtaccg gaacgccacc
     3961 ctgccagaca acgcggtctg gacatcgtcg gtctgcgctg attgcaaagc cgcgcccctg
     4021 gtgatcagca aggcaccggt caagggcaag ccgcgacggg agatcgtcgt ctcctgcccg
     4081 tcctgcgact ccagcgcatc agccaggccc ggaggcagga catggacaga cgagcacatc
     4141 gcggtgcccg agttcgcgca gaacgagacg cgcagcctgg cgaagatccc cgttattttg
     4201 ccgcaggggg agcagccgca gctgctcaaa agaccaggga cagggcgcgg tccaggacgc
     4261 ccccgcaagc gcatccccct gaccctcgac cgggtaccag agagccggtt caaccgcctc
     4321 gccctttccg tccttgccgc cgtcgggcgc tgggactaca tcaacgacat catccggcgc
     4381 atcgatcgga accgcggcga cgccgccacc ctgatcgccc ttgccgacca catccggacc
     4441 aaccgaccag agagagattt atgaccgaaa ccacccgtcc gatcctgacc atcaagcgac
     4501 gcaaccgcac ggtctacgtc ccgccggaaa aggccgcgaa atctgagccg cagccagccg
     4561 aacggactac cagcaaggcg aaggtacagc caaaagcgaa agccccgcag aagcccgcac
     4621 agaagcccac agcggcaaag ccgaaaaaga cgcctgaaca ggtcgccgag gggatccgca
     4681 gacaggagga gaacgaccgc cgccagcagg acatcgcgat cgccaacaag tccaaaaagg
     4741 cgctggccaa ccgggtgacc aaagcattcc tgaaagagca ctggcctgac ttgctgaccc
     4801 ggggagttga ccgtcgcccc atggcaaagg gcatcatcga gcagatcctg acccgaggcg
     4861 cagagctgaa catgccgcca gaggcagacc gcaaagccgt ccgtcgcatc ctgggcattg
     4921 tcacgggtac gagctcgtac cagcagagcc tcatcgacca gtgcatgcgc tacgacctgg
     4981 acggcaaccc caccgaacca gcaaccccgg aggaggccga aaacgccaaa gcccgcctga
     5041 cagagatcaa ggcattccgg cgcaaggcac gccaggcgaa gggcgaaaaa aagggcgcat
     5101 aacgcgcccc gtctcaccca gcaccatgta ggcgcagcac gacgttcagc agcacggcga
     5161 gcagctgcga cacgttgcgc gatccccctg gcctttcgcg cagcaacaac cccgtcaggg
     5221 atcaccacct cagggatgac cagacgcgag acggcaaact cactcatcat cagcccccag
     5281 gaccgcacca atagcacgcc cgaaagcatg ccgatcaagc gcgtctgagg ccgcagcaac
     5341 acctgcgtct gtctcctgta aataccgggc gcggcggctc ttcagatacg ccccccagcg
     5401 atacagcgac ggctcatgta acgcgaacgc gtgcggttgc ccggccttga tcagcgattc
     5461 ctgatacagc gccagcttcg atcgttcacc atcatccctg tcaccaggac gagcctccag
     5521 aacaggcagc aacgagatca gcgcaagacg gtggccagca gagtaacaac cacctgccag
     5581 cggcatccgc gtcttaccct gcaggtggcg cggcatcggc tttactcgtc ccaattgata
     5641 ccccgggcag caggggagag agacgcctgt tgctgcacct gagcacgcac cgcagcgaac
     5701 gccggagcac gcgacgcatc agggagtccg cgagaggagg ccagcacgcc gtcaagcatc
     5761 accagatcgg caggagccac gcccgcctgt ttcatctcag tcaggaacgc cgcatcctgg
     5821 atggactgag cacgcgcccg gtgaaccgac tccgtaggag aggcaaccgg agccccgatc
     5881 ggcgcgaacg tctgcgcagc accgcccgtc tccagcacct gcgccagcgc gtcgccggcc
     5941 ccggtagatt ttgccagcgt cgcctcatgg cgaagccggt cacacagcat cgaaaatgca
     6001 gacatttacg cctccatgcc gcgattgcgg cgcagaattt cgatcgcacc ctgcgtggag
     6061 aacagctggt tcaggcggcg atcaggattg ataacagtac ggtacaaact gcgccccgcg
     6121 tcggactcgg caagcagcgt cgcctcatcc atcgccagct tcagcagctg ctcaatacgc
     6181 tgtacgcgca cggcgtgcgc caggttgaac aggccgatcg cagccgccgc atcacggcgg
     6241 tcagcatcct gcagcagcgc gtcacgctcc cgggccacat cagcctcagc agcctcggcg
     6301 gcaaccagct cggcctcgat atccggcagc aggaacgcag cgacgcccgc atcggggctc
     6361 acagtctcgc cagcacgcag cgccgtcttg ccgtcggcaa tcagcccgcg caggcgttca
     6421 gcttccgtcc tgagcccttc caccacgcga gcggcgtcaa tgcgtcgcgt ttccacgtcg
     6481 gctgctgcct gacgcatttc acgcgccacc cggcgatcgt caagcgcggt aagttgagcg
     6541 gaggagttag gatccaccga caggcaagga aggtcataaa cgggaaaatg gtcactcgcc
     6601 atttcagcaa gcgtggtacg cagccaggtc gcgtccgggc attcggtttt gatttcggtc
     6661 atggtttggt tctcagcaag ttatcagcaa agcggcagca aacgccgctc agacagcatg
     6721 ccgtcacgac accgcgcaga catcaacgca gagggcgcag ggctctcgcc cagcgcggag
     6781 agccgcctgg aggccgtcgc taatccccta cattccggga cacccgacaa agcgacgaaa
     6841 tagacacttt agcgatagac tttcggtaca gttgtggcat gttgtgtcga aagagacgta
     6901 tcggtcagag gagagaaaaa agtgagcaaa acatacggtt acgttcgcgt atcaaccgac
     6961 gaacaaacca gcaacagcca gcgcgacgcc atcatcgccc ggttcccaac agcctccatc
     7021 ctcgccgacg acgggatcag cgggacggta ccaccacgcg agcgtccagc cctcggcatc
     7081 ctcctgaacc agatcctgca ggagggcgac acgctggtca tctacgcgat cgaccgcatc
     7141 ggcaggaacg cccgggacgc cctcgaactg gtcgaggagc tggagaaacg aaaagtaacc
     7201 ctggtcagca tccgcgaggg tgtcgatttg agcagcgccg tcggacaggc cgtcctcggc
     7261 atcatggcga gtttcgcgca gatggagcgc aagctcatac tggaacgcca ggcggcaggg
     7321 atcgaggccg caaagagccg tggccagaag ttcggacgcc cgaccaagat cggcgcgaaa
     7381 gaagcggggg agatagtcat gcgccgcgcc atgggggtac caatagccac catagccaag
     7441 cagttaaatc tgagcaggag cgcgatttac cgccaccttg agaaggtcga cgcggtagcg
     7501 ccggagtaag agagagcgca gcggtgtagg tggctccaac cattccacac cgccgcaacc
     7561 cagcccgggg aacgcatgag gagcagaccc gggcaccatt cccaacaagg aacagaacca
     7621 tgataaacca agcagcaaca ccgcgctatc ccggcctgag cattgaacac ggcgagatcc
     7681 gccagttcgg caagccccgc cattgcgccg ccaaccgcaa aggccagtac cagaccaccc
     7741 tccgcgacag cgccggtcgg taccagacag tcagcatcat cagcctttac gcctgggaag
     7801 catgaccata acgaaagcct tacaggtgta agcagcaagc aataacaaaa gccttacgcc
     7861 attacgaacc acttacaggg gcgcgggagc gcccccagaa accagaatca taaggagaga
     7921 acgatggcat ttgaaaacat tccccgtagg ttccagagat ggaaggtaat catggttccc
     7981 ggagcaaagt catatgagtc atgggacgag atggttaccg gcgagaactt ctccgaagaa
     8041 accaggatga aaacgtacaa aaagcaccgc accaaggcca tcgaccgcac cgtggcaaac
     8101 caggagtaca tccataccat gacggaggac gggatcaccg tcaggtaccg cctcgaacgc
     8161 tggcgctaac cccagctagg agcgcagcga ctgctgcgcc tcctccctta cccagaacgc
     8221 accagagcca ttctaagcgc ctcagccaca aaaataccca accgcacgac cacgcacgca
     8281 caaacgccgt gtacccccca aaaacccccg ccattttcag cgcgtgacgt ttcaatacag
     8341 gagagaaacc aaccggagca ggacaccatg aagaaataca ccaccgagca gaaagcccag
     8401 gcgctcagac tactggagca ggacggcgca accgcagcca ccgtcgcacg caccatgggg
     8461 atcccacccc gcaccgtcag agattgggcg aaagcccgca ccgacgcacc cagcaacgtc
     8521 ctcagcatcg aggagatgcg cgaacgcgca cagcgagccg tcgaggccac cccacaggca
     8581 gcgatccgac gcctaaaaaa ccactttgta cagcgccagt ttgagctgct acagcgccac
     8641 gccaccgacc tgcaagccct ccgcacagct tcgctacagg ccatgctgga gaaggacgcc
     8701 accatggtca aagcgatcag cggccttatg acatccctac tcaagacgca ggaacgcgag
     8761 cgcgtcatct acgagatcaa gccaggcacc gaggccgaca tcatgcgcga gggcatgaat
     8821 cgccaacaga gctgaaaacg gcgggaaaac cgccttttac cgccgcttta ccgccgcaga
     8881 aaacccggga gcccgcgaaa tacgcggatc cgcacgttaa cgagttgtta ccgctcgcgt
     8941 gcgcgagggc aagccctcac gcagaaccaa cagacgacca cccagcgcga ggcgaaagcc
     9001 tcgtgccctc agcgccaccc aaacctccga tccccctcag aaccactacc accgaccatc
     9061 ccggcacgac gaacccatcc accgatctaa taagacaagc aaagtgcatc cggcagggtg
     9121 cagctgcggc gcgtcgattc caagatgatc cacccgttcc acccgatccg gcatagattc
     9181 ataaatagta aaaaaaacaa ctaattgttc aattagtgag catttacccc ctatttaccc
     9241 aatttattca ttttttgttt ttaattagaa aatagggtgg aacgggtgga acacaacaat
     9301 gaaagccttt aaacacgagg ccttagctgt tccatccacg ggcggaacac gggtggaacg
     9361 ggtggaacac ccgggtggaa caggtggtac aaaaacggcg tgatgatcca cccgtgatcc
     9421 acccgggtgg aacaataaaa aaggggagca tatagctccc ctcttacgga aaagtaaccc
     9481 ttacacgaca gcttgcgttc gacggaagta gccacgaact aacgcaccgt ttatgcgctt
     9541 cctgccaacc tcatagccca atcgggacat gatagccgcc atgcgctgat gctgcttgtt
     9601 gctggtatgg ccaatcatga gccctacctg agagaacaag gccttcgtcg gcacgaaagc
     9661 agtcgggtcg cagtcgtcaa cgtccagctt gagcagctcg gcgatctcgt cttcccacgg
     9721 atcctcgacg cggaactcgt catgcacctt acgcgccagc gtttcagcgg cctcccacat
     9781 caccccattc tcattgaaca ggtggagcgc ttcagcccac agctgcgagc ggtttttctc
     9841 gatggccgcg cagtccacgt ccccggaatt catgggcaaa tagcggcggt tccccgtcga
     9901 gtcattgagg atctgcttgt tgttcgtggt accgatgaac accacgcggc gcgggtttcg
     9961 caccttgaac tctttaaatt tcggcaccca ctcgtcgtgg gcagcggaga agaacgcttt
    10021 caccgattcg gagtcgcgcc cgtggaggcc gcgcagctcc tccagctcgc caatcaggca
    10081 cccacgcata cggcgcacta gggagtcgtc cttgtcgttc aggttgaagc tggagtagga
    10141 gtcagggaat ggcgacataa ggcgaacgcc cgtcgatttg cgggcaccct gtcgcccgta
    10201 cagcagcgga accatgtcgg ccttgattcc gggattcatt acgcgcccgg caagcgccgt
    10261 ccaggtgtag aggctgaccg ccgccaggta ctcgggatcc ccttggcatt tgaagcaccg
    10321 ctcgaagaag taactgacgc gaggtttgcc gtcccattcc tgagccgtca gccaacgctg
    10381 ggcgctgtcg aatttgttct catcgcagac gtagaacatg gcgtcgcggg cattgtcctt
    10441 ggtcaccttc tcgaagtcgg cagcagcgag gcgcagacgc agctcggtaa ctaggttgtc
    10501 ggacagcggg taccattgcc cgttcacgaa cgccccctcc tccgcaaaga actcatcgaa
    10561 agcgagctgg atgccggtga cggaatggca gcgcatagcg gcgacaacgt tctcaagaga
    10621 ggacgagtag cgccccttcc ggtagttgat ctccagctcc acgggaaacg cggtagtcgg
    10681 gtattttttt tgtagagacg ggcgtcccac cttggcagcg gcgatcggcg ttacgttgtc
    10741 ggcagcagtg ccggaatttt catcaatttg tgacacgcaa ttactccttt aaaaacgtag
    10801 gagtcggcgt caggcggggg cttacgaggg aaattcacac ttgcgcgatc ttatcgacgt
    10861 ggtacacttc tctttgagtt tgaggagtac gctgcgcaag tgctattctt ccttcgagaa
    10921 cgtcccgcta agacgtgact cgaattaatc ggaggagtta ccagctcccc cggcagaaaa
    10981 aggtgaccac ccaacaggtc gccttttttt gtgcccgaag atccccaacc ggatccgcag
    11041 acgccagatc agcttacccg atcccaaccc tccacgccac ttagcgccgc gcacttatcg
    11101 cgctgtcgtg atcacgccca gctcaatctc tgcgccgcct ctgctattta tccatgtaca
    11161 caaacggcac cccggcgacg caaagccgtc gcccctctgt gcacgacaac tgcacgacgt
    11221 cgaattcgac gcgcacgaca aaacgcatta cactacgcaa gacaaacagc acgacaaaac
    11281 gcacgacgtg gagagcagca gccatgagag agaaaaccaa aaccctgacc gttcgcctac
    11341 ccgttagcct gatcgaacgc atcgagcaga acgcagcacg aaccggagca acccgcacgg
    11401 atgctgtcat agaggcgctg aacgccggac ttggcacgaa gccggaaggg atggacacca
    11461 aacttttagc tgccatcgaa gcgctgaggg ctgaagtcag ggcgctgtcc gtcggcggta
    11521 aacctgcacg acaaaccgca caacaaacag caccacaaag cgcacaacaa cctgcaagac
    11581 agatagtccc ccggggagcc gatccgcgct tccaggccgt cagtgatgag gctgaccagc
    11641 tcattgtcag catgaccgca gagaacgcga ctctgcccgc catcgcgtcg gcactgaacg
    11701 cagcagggca ccggacagcg acgggacagg agtggaacac cagccgtgtc cgggactatc
    11761 gccataagtt gcgggaaagt gggctactga attagcagtc ctaagtgaca tagctaaata
    11821 tgataaaatt cgaacataaa aattttacaa ggaaaagaag tggctatcgg tgatgatgct
    11881 atccgtgacg ctttctatgc ttttacacag caagctgaag aaatggatga taaaggtctc
    11941 cctcaggaag tttgggagac gccttgtttt acctatctga tgactaagaa gcagttcaat
    12001 caaatgaaag ttgtttgtca gagaaacggc tgggacatac ctgcatcacc agcaataccg
    12061 atcacttggg caatgtttag gcatgtgcta tctgctcgta actcgaagga taagctaagt
    12121 tggcaagagt gtgcggagat tttggcaact gcattctcag tgcagagcaa tgtgtacgtt
    12181 aacagagatt actcggagca gactattgtg ctcaatgctg ttcgtcgcat taacgttgct
    12241 ggggctggct ttttcgcaat ggcgatagtt gatgtctctg aaaataattt ggcccccgtg
    12301 actgcatacc atgcaacgga ggccaaatgt aaagctatac agcgagggtg ataggaagga
    12361 cgcccattta agcaattctc ctcaatttaa tgagaatgaa ccataacgcc taaatatttc
    12421 ccttcattgg ttcctttcgg atctagcagc atcggcggtt ttctgctgtc tatcaaattc
    12481 actgttatta ctaggaagcc gcaacataac ttcccaacag gagaccagcc tcctgactgc
    12541 ccagcgcaaa gggttaatta ctggttaata ccccctgcga atgctcttgc agtacaacaa
    12601 tagtaggcta ttgttgacgt agattcaact ggtttgttta taaccaagcg gcacgaggag
    12661 cgggtttaca ggtttttata gctctttaga ggcggttaac catattgcga tatcaggtaa
    12721 ttatagatct tgaaatcatt aaatttatca attatgatta attttatgat taatttttga
    12781 tctatagagg tactttgatg gatattacga tatctgacgc tacatatagc cgtcttgctg
    12841 cacaagcaaa gggatttgaa actcccgaac aggtaataa
//
