LOCUS       NZ_OX291747            12879 bp    DNA     circular CON 03-SEP-2023
DEFINITION  Serratia marcescens strain SJC1051 plasmid 2, complete sequence.
ACCESSION   NZ_OX291747
VERSION     NZ_OX291747.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA13201019
            Assembly: GCF_946413195.1
KEYWORDS    RefSeq.
SOURCE      Serratia marcescens
  ORGANISM  Serratia marcescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Serratia.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (11-AUG-2022) WELLCOME SANGER INSTITUTE, Pathogen
            Informatics, Wellcome Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/02/2023 07:36:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,306
            CDSs (total)                      :: 5,172
            Genes (coding)                    :: 5,097
            CDSs (with protein)               :: 5,097
            Genes (RNA)                       :: 134
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 93
            ncRNAs                            :: 19
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 29 of 76
            Pseudo Genes (incomplete)         :: 46 of 76
            Pseudo Genes (internal stop)      :: 15 of 76
            Pseudo Genes (multiple problems)  :: 11 of 76
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OX291747.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12879
                     /organism="Serratia marcescens"
                     /mol_type="genomic DNA"
                     /strain="SJC1051"
                     /serovar="NA"
                     /isolation_source="Bloodstream"
                     /db_xref="taxon:615"
                     /plasmid="2"
     gene            complement(join(12716..12879,1..1126))
                     /locus_tag="N4J69_RS26405"
     CDS             complement(join(12716..12879,1..1126))
                     /locus_tag="N4J69_RS26405"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_157698538.1"
                     /translation="MNDDNDTTEATQPSTEALKCVGAAERFPDIMPGVLFVTCPGGCSL
                     RVEACRQIYEQSHLDRTIENPHLECHRCPTGLALWVGTEQPPDAPLTTPADTRKLCPRC
                     SRKDNRLIAPNKPGSSLCVSCWNREREATIGANARGRVNRTPPFVSPFLIGIGDGWQVW
                     YGIHQGEALVRAMRANPGARFHDRRPGPVGQTRRDGFVYYCPEHREPLRWNGGDGHAGE
                     VELACPRCQPWAAPLSVAPTFQTVSFQTPHDAAHQYRNATLPDNAVWTSSVCADCKAAP
                     LVISKAPVKGKPRREIVVSCPSCDSSASARPGGRTWTDEHIAVPEFAQNETRSLAKIPV
                     ILPQGEQPQLLKRPGTGRGPGRPRKRIPLTLDRVPESRFNRLALSVLAAVGRWDYINDI
                     IRRIDRNRGDAATLIALADHIRTNRPERDL"
                     /name="hypothetical protein"
     gene            1482..1691
                     /locus_tag="N4J69_RS26410"
     CDS             1482..1691
                     /locus_tag="N4J69_RS26410"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765954.1"
                     /translation="MKKRIYTADLAALLNVSLRTLSRLSSRGIVPTPAGRSLRGGHYWL
                     AGDPVLKRFIADQRRPGRAPYGVR"
                     /name="hypothetical protein"
     gene            1678..2859
                     /locus_tag="N4J69_RS26415"
                     /old_locus_tag="SAMEA13201019_05242"
     CDS             1678..2859
                     /locus_tag="N4J69_RS26415"
                     /old_locus_tag="SAMEA13201019_05242"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765953.1"
                     /translation="MAFDNSHLTDAGLFWRAVSAAGAPVDREDWLRLCSGIACWASLCG
                     EDGLAAIEAWSTRHNRGSAHHRSQYRHFLKLKGVTNPEAMAQVFLRFSGEVYWRLDSNR
                     TPPSTEQVAALAERKRRSIEAVARREDADRRKADKAAADAVRMLAKGDGNPAYTPYWRN
                     KTTIARRGGVSLPPLPADLRVGGLFRSFEPRAYWSRCLLVPAYRLTDDRQLVGDALEAI
                     CGVCSAGGKTGDKFSPAGTQKAGRFYPMPGFMDVLDTSPHAPYSPLFVCEGFATAVALH
                     HLTKGKVAVCAAFSIAGFGSCVASLRRFWPDVDVMLVPDHGEAYRLAHKAAYGDEREPV
                     PTIPGAAVVSFDGLDRFTPRDNLDWFDVLVEEGEDRARELLRYAVRHARLERR"
                     /name="hypothetical protein"
     gene            3085..3543
                     /locus_tag="N4J69_RS26420"
                     /old_locus_tag="SAMEA13201019_05243"
     CDS             3085..3543
                     /locus_tag="N4J69_RS26420"
                     /old_locus_tag="SAMEA13201019_05243"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765952.1"
                     /translation="MKSKTELREAATARSLAVIATEMSEWSLDGFSHLKLPNFSAGERQ
                     QTLSGSVVVDRPPFDYEWAGTEKFNTLATRALQVKLPASRERNYAWLCGVERETLATAL
                     LVELFSVTGCVAFAGLGKVADLAFLTLDESEAGQIRAAMLQWLDGAAA"
                     /name="hypothetical protein"
     gene            complement(3798..4382)
                     /locus_tag="N4J69_RS26425"
                     /old_locus_tag="SAMEA13201019_05244"
     CDS             complement(3798..4382)
                     /locus_tag="N4J69_RS26425"
                     /old_locus_tag="SAMEA13201019_05244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004589499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351424.1"
                     /translation="MDITISDATYSRLAAQAKGFETPEQVINRLIDVVEIDHDTRPELF
                     FNPEGEADFKKALLKSKQAKVEMFKRDGSCETGVWNARAISEESSVRANIWSGYLRGWK
                     EKGIVRAVFTVQEVPDLPGAAESVQWNDYTISRTFSGGISVQRNGMPVTIVKPFLRDVA
                     HDLKISLLNSNGNEMNTRQLGAAIIKKLNNS"
                     /name="hypothetical protein"
     gene            complement(4829..5320)
                     /locus_tag="N4J69_RS26430"
     CDS             complement(4829..5320)
                     /locus_tag="N4J69_RS26430"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351425.1"
                     /translation="MAIGDDAIRDAFYAFTQQAEEMDDKGLPQEVWETPCFTYLMTKKQ
                     FNQMKVVCQRNGWDIPASPAIPITWAMFRHVLSARNSKDKLSWQECAEILATAFSVQSN
                     VYVNRDYSEQTIVLNAVRRINVAGAGFFAMAIVDVSENNLAPVTAYHATEAKCKAIQRG
                     "
                     /name="hypothetical protein"
     gene            complement(5385..5876)
                     /locus_tag="N4J69_RS26435"
     CDS             complement(5385..5876)
                     /locus_tag="N4J69_RS26435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558888.1"
                     /translation="MREKTKTLTVRLPVSLIERIEQNAARTGATRTDAVIEALNAGLGT
                     KPEGMDTKLLAAIEALRAEVRALSVGGKPARQTAQQTAPQSAQQPARQIVPRGADPRFQ
                     AVSDEADQLIVSMTAENATLPAIASALNAAGHRTATGQEWNTSRVRDYRHKLRESGLLN
                     "
                     /name="hypothetical protein"
     gene            6404..7699
                     /locus_tag="N4J69_RS26440"
                     /old_locus_tag="SAMEA13201019_05246"
     CDS             6404..7699
                     /locus_tag="N4J69_RS26440"
                     /old_locus_tag="SAMEA13201019_05246"
                     /inference="COORDINATES: protein motif:HMM:NF017116.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="WP_119879886.1"
                     /translation="MSQIDENSGTAADNVTPIAAAKVGRPSLQKKYPTTAFPVELEINY
                     RKGRYSSSLENVVAAMRCHSVTGIQLAFDEFFAEEGAFVNGQWYPLSDNLVTELRLRLA
                     AADFEKVTKDNARDAMFYVCDENKFDSAQRWLTAQEWDGKPRVSYFFERCFKCQGDPEY
                     LAAVSLYTWTALAGRVMNPGIKADMVPLLYGRQGARKSTGVRLMSPFPDSYSSFNLNDK
                     DDSLVRRMRGCLIGELEELRGLHGRDSESVKAFFSAAHDEWVPKFKEFKVRNPRRVVFI
                     GTTNNKQILNDSTGNRRYLPMNSGDVDCAAIEKNRSQLWAEALHLFNENGVMWEAAETL
                     ARKVHDEFRVEDPWEDEIAELLKLDVDDCDPTAFVPTKALFSQVGLMIGHTSNKQHQRM
                     AAIMSRLGYEVGRKRINGALVRGYFRRTQAVV"
                     /name="VapE domain-containing protein"
     gene            complement(8345..8812)
                     /locus_tag="N4J69_RS26445"
                     /old_locus_tag="SAMEA13201019_05247"
     CDS             complement(8345..8812)
                     /locus_tag="N4J69_RS26445"
                     /old_locus_tag="SAMEA13201019_05247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324036.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_070559148.1"
                     /translation="MKKYTTEQKAQALRLLEQDGATAATVARTMGIPPRTVRDWAKART
                     DAPSNVLSIEEMRERAQRAVEATPQAAIRRLKNHFVQRQFELLQRHATDLQALRTASLQ
                     AMLEKDATMVKAISGLMTSLLKTQERERVIYEIKPGTEADIMREGMNRQQS"
                     /name="transposase"
     gene            complement(9011..9256)
                     /locus_tag="N4J69_RS26450"
                     /old_locus_tag="SAMEA13201019_05248"
     CDS             complement(9011..9256)
                     /locus_tag="N4J69_RS26450"
                     /old_locus_tag="SAMEA13201019_05248"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558916.1"
                     /translation="MAFENIPRRFQRWKVIMVPGAKSYESWDEMVTGENFSEETRMKTY
                     KKHRTKAIDRTVANQEYIHTMTEDGITVRYRLERWR"
                     /name="hypothetical protein"
     gene            complement(9375..9560)
                     /locus_tag="N4J69_RS26455"
                     /old_locus_tag="SAMEA13201019_05249"
     CDS             complement(9375..9560)
                     /locus_tag="N4J69_RS26455"
                     /old_locus_tag="SAMEA13201019_05249"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879885.1"
                     /translation="MINQAATPRYPGLSIEHGEIRQFGKPRHCAANRKGQYQTTLRDSA
                     GRYQTVSIISLYAWEA"
                     /name="hypothetical protein"
     gene            complement(9671..10258)
                     /locus_tag="N4J69_RS26460"
                     /old_locus_tag="SAMEA13201019_05250"
     CDS             complement(9671..10258)
                     /locus_tag="N4J69_RS26460"
                     /old_locus_tag="SAMEA13201019_05250"
                     /inference="COORDINATES: protein motif:HMM:NF012464.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_181654175.1"
                     /translation="MSKTYGYVRVSTDEQTSNSQRDAIIARFPTASILADDGISGTVPP
                     RERPALGILLNQILQEGDTLVIYAIDRIGRNARDALELVEELEKRKVTLVSIREGVDLS
                     SAVGQAVLGIMASFAQMERKLILERQAAGIEAAKSRGQKFGRPTKIGAKEAGEIVMRRA
                     MGVPIATIAKQLNLSRSAIYRHLEKVDAVAPE"
                     /name="recombinase family protein"
     gene            10518..11174
                     /locus_tag="N4J69_RS26465"
                     /old_locus_tag="SAMEA13201019_05251"
     CDS             10518..11174
                     /locus_tag="N4J69_RS26465"
                     /old_locus_tag="SAMEA13201019_05251"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879883.1"
                     /translation="MTEIKTECPDATWLRTTLAEMASDHFPVYDLPCLSVDPNSSAQLT
                     ALDDRRVAREMRQAAADVETRRIDAARVVEGLRTEAERLRGLIADGKTALRAGETVSPD
                     AGVAAFLLPDIEAELVAAEAAEADVARERDALLQDADRRDAAAAIGLFNLAHAVRVQRI
                     EQLLKLAMDEATLLAESDAGRSLYRTVINPDRRLNQLFSTQGAIEILRRNRGMEA"
                     /name="hypothetical protein"
     gene            11175..11558
                     /locus_tag="N4J69_RS26470"
                     /old_locus_tag="SAMEA13201019_05252"
     CDS             11175..11558
                     /locus_tag="N4J69_RS26470"
                     /old_locus_tag="SAMEA13201019_05252"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559064.1"
                     /translation="MSAFSMLCDRLRHEATLAKSTGAGDALAQVLETGGAAQTFAPIGA
                     PVASPTESVHRARAQSIQDAAFLTEMKQAGVAPADLVMLDGVLASSRGLPDASRAPAFA
                     AVRAQVQQQASLSPAARGINWDE"
                     /name="hypothetical protein"
     gene            11564..11920
                     /locus_tag="N4J69_RS26475"
     CDS             11564..11920
                     /locus_tag="N4J69_RS26475"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559062.1"
                     /translation="MPRHLQGKTRMPLAGGCYSAGHRLALISLLPVLEARPGDRDDGER
                     SKLALYQESLIKAGQPHAFALHEPSLYRWGAYLKSRRARYLQETDAGVAAASDALDRHA
                     FGRAIGAVLGADDE"
                     /name="hypothetical protein"
     gene            complement(12078..12719)
                     /locus_tag="N4J69_RS26480"
                     /old_locus_tag="SAMEA13201019_05253"
     CDS             complement(12078..12719)
                     /locus_tag="N4J69_RS26480"
                     /old_locus_tag="SAMEA13201019_05253"
                     /inference="COORDINATES: protein motif:HMM:NF016255.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_070559060.1"
                     /translation="MTETTRPILTIKRRNRTVYVPPEKAAKSEPQPAERTTSKAKVQPK
                     AKAPQKPAQKPTAAKPKKTPEQVAEGIRRQEENDRRQQDIAIANKSKKALANRVTKAFL
                     KEHWPDLLTRGVDRRPMAKGIIEQILTRGAELNMPPEADRKAVRRILGIVTGTSSYQQS
                     LIDQCMRYDLDGNPTEPATPEEAENAKARLTEIKAFRRKARQAKGEKKGA"
                     /name="ProQ/FINO family protein"
ORIGIN
        1 ctggtacccg gtcgagggtc agggggatgc gcttgcgggg gcgtcctgga ccgcgccctg
       61 tccctggtct tttgagcagc tgcggctgct ccccctgcgg caaaataacg gggatcttcg
      121 ccaggctgcg cgtctcgttc tgcgcgaact cgggcaccgc gatgtgctcg tctgtccatg
      181 tcctgcctcc gggcctggct gatgcgctgg agtcgcagga cgggcaggag acgacgatct
      241 cccgtcgcgg cttgcccttg accggtgcct tgctgatcac caggggcgcg gctttgcaat
      301 cagcgcagac cgacgatgtc cagaccgcgt tgtctggcag ggtggcgttc cggtactggt
      361 gcgcggcgtc atgcggtgtc tggaagctga ccgtctgaaa cgtgggggcg acgctgagag
      421 gtgccgccca tggctggcac ctgggacaag caagctccac ctctccggcg tgcccgtcgc
      481 caccgttcca gcgcaggggc tcgcggtgtt cggggcagta gtacacgaaa ccgtcgcggc
      541 gtgtttgccc gaccgggcct ggtcggcgat cgtggaaccg tgcgcccggg ttggctcgca
      601 tggcgcggac gagcgcctcg ccctggtgga tgccgtacca gacctgccag ccatcgccga
      661 tgccgatcag gaacggcgag acgaacggtg gggtgcggtt gactctcccg cgtgcgttgg
      721 ctccgatggt ggcttcgcgt tcgcggttcc agcaggagac gcacaggctc gaaccgggct
      781 tattgggggc gatcaggcgg ttgtctttcc ggctgcaacg ggggcagagc ttacgggtgt
      841 ctgccggggt ggtcagtggt gcgtcagggg gctgttcggt accgacccaa agcgcgaggc
      901 cagtggggca ccggtggcac tcgaggtggg ggttttcaat cgtgcgatcg aggtggctct
      961 gctcataaat ctgtcggcat gcctcgaccc ggagggagca cccgccgggg caggtgacga
     1021 acaaaacgcc gggcatgatg tcggggaacc gctccgcagc gcctacgcac ttcagtgcct
     1081 cggttgacgg ctgcgtcgct tctgtcgtgt cgttatcgtc gttcactgct ccccctgcgt
     1141 cgaaatggtc gccagacctc gccagcactg gctgtgcgtc ttttttagta tctcacaaaa
     1201 aacgccactt tggcgttaat tgtgttaagc ttgtcttact gattcctgac gagcagttgg
     1261 gaaacatgaa accggatcgc ccggtgccgc tttccctcct ccccaacgag gcggggttgt
     1321 aaacgaggat gcgcgcttcg tccttggcag gtgcgagtaa gcgagaaggg ctgctgtcct
     1381 gccgctatgc ggtaagtcct caagggcggc tttatcgata atcgtcactc ccgccccccg
     1441 atgcccgtta agctgagggg ggcacctatc tggtactccc aatgaaaaaa cgaatctata
     1501 ccgctgacct cgctgcgctg ctgaacgtgt cgctgcgcac gctctcccgc ctgagttcgc
     1561 gggggatcgt tccgactccg gcagggcgtt cccttcgtgg cgggcattac tggctggctg
     1621 gggatcccgt gctcaaacgc tttattgccg accagcgtcg tcccgggagg gctccttatg
     1681 gcgttcgata actctcacct gactgacgct ggcctgttct ggcgtgccgt ctctgcggct
     1741 ggggctccgg ttgaccgcga ggactggctg cgcctctgtt ctggcatcgc atgctgggca
     1801 tctctctgcg gagaggacgg gcttgctgct atcgaggcct ggtctacccg ccacaatcgc
     1861 ggatctgcgc atcaccggtc gcagtaccgg cacttcctga agctgaaagg cgtaaccaat
     1921 cccgaggcca tggcgcaagt attcctgcgg ttctcaggcg aggtgtactg gcggctcgac
     1981 tcaaatcgca cgccgccgtc gactgaacag gttgctgctc ttgctgaacg gaaacgccga
     2041 tcgatcgagg cggtggccag acgcgaagat gccgaccggc gcaaggccga taaggctgcg
     2101 gctgatgcgg tcaggatgct ggcgaaaggc gacggtaatc cggcctatac cccgtactgg
     2161 cgcaataaga ccacaatcgc caggcgtggt ggcgtcagcc tcccgcccct ccccgctgac
     2221 cttcgtgtgg gtggcttgtt ccgctcgttc gaaccgaggg cgtactggtc gcgctgtctg
     2281 cttgttcctg cctatcgcct gaccgatgat cgccagctgg ttggcgacgc gctggaggcc
     2341 atctgcggcg tctgctctgc tggcggcaaa accggcgaca agttctcccc tgcaggtacc
     2401 caaaaggcgg gacggttcta tccgatgccc ggctttatgg acgtgctcga tacctcacca
     2461 catgcgccct actcgcctct gttcgtctgt gaggggttcg ccacggcggt tgccctgcat
     2521 catctgacga agggcaaggt ggcagtctgc gcggcgttct caattgccgg gttcggcagc
     2581 tgcgtggcgt cgctgcgccg gttctggcca gatgttgatg tgatgctggt accggatcac
     2641 ggcgaagcgt accgcctggc gcataaagcg gcctatggcg atgagcgaga gccggtcccg
     2701 acaattccag gcgcggcggt tgtgtcgttc gacggcctcg atcgcttcac gccccgggat
     2761 aacctcgact ggttcgacgt gctggttgag gaaggggaag atcgggctcg tgagctgctg
     2821 cgctacgcgg ttcgtcatgc ccggcttgag cggcgttgat tggcgtgtcc gaatggtgcg
     2881 cctttcggga catctttttt gccgtcgtgg cgtctggttt agcgaacgac tttcgagaca
     2941 ctaccgatgc ttttttgatg agacggacta aagcgacgca ccggcgctgc cgtcgtgacg
     3001 ctatcctgcg atcggtttct cacagcagca taaagcccgg cctcgtcttg atgtcgggtt
     3061 tttttttagc ccaaaggagg gcacatgaaa tcaaagactg aactacgcga ggccgcgacg
     3121 gctcgctctc tggcggtgat cgccactgaa atgtcggagt ggtcgctcga tgggttctcc
     3181 cacctcaagc tgccgaactt ctccgctggg gaacgccagc agacgctgtc cgggtcggtg
     3241 gtggttgatc gcccgccgtt cgactacgag tgggctggta ccgagaaatt taacactctg
     3301 gccacccgtg cgctgcaggt gaaacttccg gcatcgcgtg agcgtaacta cgcctggttg
     3361 tgcggcgttg aacgggagac gctggcgacg gcgctcctcg tggagctgtt ctccgtcacc
     3421 ggctgcgtgg cgttcgccgg gctgggtaag gttgccgatc tggcgttcct gacgctggac
     3481 gagagcgagg cggggcagat cagggcggcg atgctgcagt ggctcgatgg ggcggcggcg
     3541 taggggctcg atcctcgatc agctggagtg ggaagggcga ctgatcgagg aggccatggc
     3601 gacggaactg cggggcgacc cggtgcgctg cgaccacctt gctgcggcgc ggttatggct
     3661 ggagtgtgtt gaccgggcgt ctgatgacag gtggcgggcg ttctgcctcg ccagctatga
     3721 atggtgcgta ttcgtcgcag tagaactctg accggcggcg gcgttgagcc gtcgctcctc
     3781 tgcgtgaagc atcgatgtta agagttattt aacttcttta tgatcgctgc gccaagctgc
     3841 cgagtattca tttcatttcc attgctattt agcaatgata tttttaaatc atgcgcaaca
     3901 tcacgtagaa atggcttcac aatagttaca ggcatgccat ttctttgaac tgaaataccg
     3961 ccactaaaag tgcgactgat tgtataatca ttccactgca cactttcagc cgctcctggc
     4021 aagtcaggaa cctcctggac agtgaaaacc gcacgaacaa tccctttttc cttccatcca
     4081 cgcaaatacc cactccaaat atttgcccga actgatgatt cttctgaaat cgcacgagca
     4141 ttccatactc cagtttcaca ggaaccatcc cttttaaaca tttcgacttt ggcctgtttt
     4201 gattttagta acgctttttt aaaatccgct tcaccttcag gattaaaaaa aagttcaggg
     4261 cgtgtgtcat gatcgatttc aacaacatcg atcagacggt ttattacctg ttcgggagtt
     4321 tcaaatccct ttgcttgtgc agcaagacgg ctatatgtag cgtcagatat cgtaatatcc
     4381 atcaaagtac ctctatagat caaaaattaa tcataaaatt aatcataatt gataaattta
     4441 atgatttcaa gatctataat tacctgatat cgcaatatgg ttaaccgcct ctaaagagct
     4501 ataaaaacct gtaaacccgc tcctcgtgcc gcttggttat aaacaaacca gttgaatcta
     4561 cgtcaacaat agcctactat tgttgtactg caagagcatt cgcagggggt attaaccagt
     4621 aattaaccct ttgcgctggg cagtcaggag gctggtctcc tgttgggaag ttatgttgcg
     4681 gcttcctagt aataacagtg aatttgatag acagcagaaa accgccgatg ctgctagatc
     4741 cgaaaggaac caatgaaggg aaatatttag gcgttatggt tcattctcat taaattgagg
     4801 agaattgctt aaatgggcgt ccttcctatc accctcgctg tatagcttta catttggcct
     4861 ccgttgcatg gtatgcagtc acgggggcca aattattttc agagacatca actatcgcca
     4921 ttgcgaaaaa gccagcccca gcaacgttaa tgcgacgaac agcattgagc acaatagtct
     4981 gctccgagta atctctgtta acgtacacat tgctctgcac tgagaatgca gttgccaaaa
     5041 tctccgcaca ctcttgccaa cttagcttat ccttcgagtt acgagcagat agcacatgcc
     5101 taaacattgc ccaagtgatc ggtattgctg gtgatgcagg tatgtcccag ccgtttctct
     5161 gacaaacaac tttcatttga ttgaactgct tcttagtcat cagataggta aaacaaggcg
     5221 tctcccaaac ttcctgaggg agacctttat catccatttc ttcagcttgc tgtgtaaaag
     5281 catagaaagc gtcacggata gcatcatcac cgatagccac ttcttttcct tgtaaaattt
     5341 ttatgttcga attttatcat atttagctat gtcacttagg actgctaatt cagtagccca
     5401 ctttcccgca acttatggcg atagtcccgg acacggctgg tgttccactc ctgtcccgtc
     5461 gctgtccggt gccctgctgc gttcagtgcc gacgcgatgg cgggcagagt cgcgttctct
     5521 gcggtcatgc tgacaatgag ctggtcagcc tcatcactga cggcctggaa gcgcggatcg
     5581 gctccccggg ggactatctg tcttgcaggt tgttgtgcgc tttgtggtgc tgtttgttgt
     5641 gcggtttgtc gtgcaggttt accgccgacg gacagcgccc tgacttcagc cctcagcgct
     5701 tcgatggcag ctaaaagttt ggtgtccatc ccttccggct tcgtgccaag tccggcgttc
     5761 agcgcctcta tgacagcatc cgtgcgggtt gctccggttc gtgctgcgtt ctgctcgatg
     5821 cgttcgatca ggctaacggg taggcgaacg gtcagggttt tggttttctc tctcatggct
     5881 gctgctctcc acgtcgtgcg ttttgtcgtg ctgtttgtct tgcgtagtgt aatgcgtttt
     5941 gtcgtgcgcg tcgaattcga cgtcgtgcag ttgtcgtgca cagaggggcg acggctttgc
     6001 gtcgccgggg tgccgtttgt gtacatggat aaatagcaga ggcggcgcag agattgagct
     6061 gggcgtgatc acgacagcgc gataagtgcg cggcgctaag tggcgtggag ggttgggatc
     6121 gggtaagctg atctggcgtc tgcggatccg gttggggatc ttcgggcaca aaaaaaggcg
     6181 acctgttggg tggtcacctt tttctgccgg gggagctggt aactcctccg attaattcga
     6241 gtcacgtctt agcgggacgt tctcgaagga agaatagcac ttgcgcagcg tactcctcaa
     6301 actcaaagag aagtgtacca cgtcgataag atcgcgcaag tgtgaatttc cctcgtaagc
     6361 ccccgcctga cgccgactcc tacgttttta aaggagtaat tgcgtgtcac aaattgatga
     6421 aaattccggc actgctgccg acaacgtaac gccgatcgcc gctgccaagg tgggacgccc
     6481 gtctctacaa aaaaaatacc cgactaccgc gtttcccgtg gagctggaga tcaactaccg
     6541 gaaggggcgc tactcgtcct ctcttgagaa cgttgtcgcc gctatgcgct gccattccgt
     6601 caccggcatc cagctcgctt tcgatgagtt ctttgcggag gagggggcgt tcgtgaacgg
     6661 gcaatggtac ccgctgtccg acaacctagt taccgagctg cgtctgcgcc tcgctgctgc
     6721 cgacttcgag aaggtgacca aggacaatgc ccgcgacgcc atgttctacg tctgcgatga
     6781 gaacaaattc gacagcgccc agcgttggct gacggctcag gaatgggacg gcaaacctcg
     6841 cgtcagttac ttcttcgagc ggtgcttcaa atgccaaggg gatcccgagt acctggcggc
     6901 ggtcagcctc tacacctgga cggcgcttgc cgggcgcgta atgaatcccg gaatcaaggc
     6961 cgacatggtt ccgctgctgt acgggcgaca gggtgcccgc aaatcgacgg gcgttcgcct
     7021 tatgtcgcca ttccctgact cctactccag cttcaacctg aacgacaagg acgactccct
     7081 agtgcgccgt atgcgtgggt gcctgattgg cgagctggag gagctgcgcg gcctccacgg
     7141 gcgcgactcc gaatcggtga aagcgttctt ctccgctgcc cacgacgagt gggtgccgaa
     7201 atttaaagag ttcaaggtgc gaaacccgcg ccgcgtggtg ttcatcggta ccacgaacaa
     7261 caagcagatc ctcaatgact cgacggggaa ccgccgctat ttgcccatga attccgggga
     7321 cgtggactgc gcggccatcg agaaaaaccg ctcgcagctg tgggctgaag cgctccacct
     7381 gttcaatgag aatggggtga tgtgggaggc cgctgaaacg ctggcgcgta aggtgcatga
     7441 cgagttccgc gtcgaggatc cgtgggaaga cgagatcgcc gagctgctca agctggacgt
     7501 tgacgactgc gacccgactg ctttcgtgcc gacgaaggcc ttgttctctc aggtagggct
     7561 catgattggc cataccagca acaagcagca tcagcgcatg gcggctatca tgtcccgatt
     7621 gggctatgag gttggcagga agcgcataaa cggtgcgtta gttcgtggct acttccgtcg
     7681 aacgcaagct gtcgtgtaag ggttactttt ccgtaagagg ggagctatat gctccccttt
     7741 tttattgttc cacccgggtg gatcacgggt ggatcatcac gccgtttttg taccacctgt
     7801 tccacccggg tgttccaccc gttccacccg tgttccgccc gtggatggaa cagctaaggc
     7861 ctcgtgttta aaggctttca ttgttgtgtt ccacccgttc caccctattt tctaattaaa
     7921 aacaaaaaat gaataaattg ggtaaatagg gggtaaatgc tcactaattg aacaattagt
     7981 tgtttttttt actatttatg aatctatgcc ggatcgggtg gaacgggtgg atcatcttgg
     8041 aatcgacgcg ccgcagctgc accctgccgg atgcactttg cttgtcttat tagatcggtg
     8101 gatgggttcg tcgtgccggg atggtcggtg gtagtggttc tgagggggat cggaggtttg
     8161 ggtggcgctg agggcacgag gctttcgcct cgcgctgggt ggtcgtctgt tggttctgcg
     8221 tgagggcttg ccctcgcgca cgcgagcggt aacaactcgt taacgtgcgg atccgcgtat
     8281 ttcgcgggct cccgggtttt ctgcggcggt aaagcggcgg taaaaggcgg ttttcccgcc
     8341 gttttcagct ctgttggcga ttcatgccct cgcgcatgat gtcggcctcg gtgcctggct
     8401 tgatctcgta gatgacgcgc tcgcgttcct gcgtcttgag tagggatgtc ataaggccgc
     8461 tgatcgcttt gaccatggtg gcgtccttct ccagcatggc ctgtagcgaa gctgtgcgga
     8521 gggcttgcag gtcggtggcg tggcgctgta gcagctcaaa ctggcgctgt acaaagtggt
     8581 tttttaggcg tcggatcgct gcctgtgggg tggcctcgac ggctcgctgt gcgcgttcgc
     8641 gcatctcctc gatgctgagg acgttgctgg gtgcgtcggt gcgggctttc gcccaatctc
     8701 tgacggtgcg gggtgggatc cccatggtgc gtgcgacggt ggctgcggtt gcgccgtcct
     8761 gctccagtag tctgagcgcc tgggctttct gctcggtggt gtatttcttc atggtgtcct
     8821 gctccggttg gtttctctcc tgtattgaaa cgtcacgcgc tgaaaatggc gggggttttt
     8881 ggggggtaca cggcgtttgt gcgtgcgtgg tcgtgcggtt gggtattttt gtggctgagg
     8941 cgcttagaat ggctctggtg cgttctgggt aagggaggag gcgcagcagt cgctgcgctc
     9001 ctagctgggg ttagcgccag cgttcgaggc ggtacctgac ggtgatcccg tcctccgtca
     9061 tggtatggat gtactcctgg tttgccacgg tgcggtcgat ggccttggtg cggtgctttt
     9121 tgtacgtttt catcctggtt tcttcggaga agttctcgcc ggtaaccatc tcgtcccatg
     9181 actcatatga ctttgctccg ggaaccatga ttaccttcca tctctggaac ctacggggaa
     9241 tgttttcaaa tgccatcgtt ctctccttat gattctggtt tctgggggcg ctcccgcgcc
     9301 cctgtaagtg gttcgtaatg gcgtaaggct tttgttattg cttgctgctt acacctgtaa
     9361 ggctttcgtt atggtcatgc ttcccaggcg taaaggctga tgatgctgac tgtctggtac
     9421 cgaccggcgc tgtcgcggag ggtggtctgg tactggcctt tgcggttggc ggcgcaatgg
     9481 cggggcttgc cgaactggcg gatctcgccg tgttcaatgc tcaggccggg atagcgcggt
     9541 gttgctgctt ggtttatcat ggttctgttc cttgttggga atggtgcccg ggtctgctcc
     9601 tcatgcgttc cccgggctgg gttgcggcgg tgtggaatgg ttggagccac ctacaccgct
     9661 gcgctctctc ttactccggc gctaccgcgt cgaccttctc aaggtggcgg taaatcgcgc
     9721 tcctgctcag atttaactgc ttggctatgg tggctattgg tacccccatg gcgcggcgca
     9781 tgactatctc ccccgcttct ttcgcgccga tcttggtcgg gcgtccgaac ttctggccac
     9841 ggctctttgc ggcctcgatc cctgccgcct ggcgttccag tatgagcttg cgctccatct
     9901 gcgcgaaact cgccatgatg ccgaggacgg cctgtccgac ggcgctgctc aaatcgacac
     9961 cctcgcggat gctgaccagg gttacttttc gtttctccag ctcctcgacc agttcgaggg
    10021 cgtcccgggc gttcctgccg atgcggtcga tcgcgtagat gaccagcgtg tcgccctcct
    10081 gcaggatctg gttcaggagg atgccgaggg ctggacgctc gcgtggtggt accgtcccgc
    10141 tgatcccgtc gtcggcgagg atggaggctg ttgggaaccg ggcgatgatg gcgtcgcgct
    10201 ggctgttgct ggtttgttcg tcggttgata cgcgaacgta accgtatgtt ttgctcactt
    10261 ttttctctcc tctgaccgat acgtctcttt cgacacaaca tgccacaact gtaccgaaag
    10321 tctatcgcta aagtgtctat ttcgtcgctt tgtcgggtgt cccggaatgt aggggattag
    10381 cgacggcctc caggcggctc tccgcgctgg gcgagagccc tgcgccctct gcgttgatgt
    10441 ctgcgcggtg tcgtgacggc atgctgtctg agcggcgttt gctgccgctt tgctgataac
    10501 ttgctgagaa ccaaaccatg accgaaatca aaaccgaatg cccggacgcg acctggctgc
    10561 gtaccacgct tgctgaaatg gcgagtgacc attttcccgt ttatgacctt ccttgcctgt
    10621 cggtggatcc taactcctcc gctcaactta ccgcgcttga cgatcgccgg gtggcgcgtg
    10681 aaatgcgtca ggcagcagcc gacgtggaaa cgcgacgcat tgacgccgct cgcgtggtgg
    10741 aagggctcag gacggaagct gaacgcctgc gcgggctgat tgccgacggc aagacggcgc
    10801 tgcgtgctgg cgagactgtg agccccgatg cgggcgtcgc tgcgttcctg ctgccggata
    10861 tcgaggccga gctggttgcc gccgaggctg ctgaggctga tgtggcccgg gagcgtgacg
    10921 cgctgctgca ggatgctgac cgccgtgatg cggcggctgc gatcggcctg ttcaacctgg
    10981 cgcacgccgt gcgcgtacag cgtattgagc agctgctgaa gctggcgatg gatgaggcga
    11041 cgctgcttgc cgagtccgac gcggggcgca gtttgtaccg tactgttatc aatcctgatc
    11101 gccgcctgaa ccagctgttc tccacgcagg gtgcgatcga aattctgcgc cgcaatcgcg
    11161 gcatggaggc gtaaatgtct gcattttcga tgctgtgtga ccggcttcgc catgaggcga
    11221 cgctggcaaa atctaccggg gccggcgacg cgctggcgca ggtgctggag acgggcggtg
    11281 ctgcgcagac gttcgcgccg atcggggctc cggttgcctc tcctacggag tcggttcacc
    11341 gggcgcgtgc tcagtccatc caggatgcgg cgttcctgac tgagatgaaa caggcgggcg
    11401 tggctcctgc cgatctggtg atgcttgacg gcgtgctggc ctcctctcgc ggactccctg
    11461 atgcgtcgcg tgctccggcg ttcgctgcgg tgcgtgctca ggtgcagcaa caggcgtctc
    11521 tctcccctgc tgcccggggt atcaattggg acgagtaaag ccgatgccgc gccacctgca
    11581 gggtaagacg cggatgccgc tggcaggtgg ttgttactct gctggccacc gtcttgcgct
    11641 gatctcgttg ctgcctgttc tggaggctcg tcctggtgac agggatgatg gtgaacgatc
    11701 gaagctggcg ctgtatcagg aatcgctgat caaggccggg caaccgcacg cgttcgcgtt
    11761 acatgagccg tcgctgtatc gctggggggc gtatctgaag agccgccgcg cccggtattt
    11821 acaggagaca gacgcaggtg ttgctgcggc ctcagacgcg cttgatcggc atgctttcgg
    11881 gcgtgctatt ggtgcggtcc tgggggctga tgatgagtga gtttgccgtc tcgcgtctgg
    11941 tcatccctga ggtggtgatc cctgacgggg ttgttgctgc gcgaaaggcc agggggatcg
    12001 cgcaacgtgt cgcagctgct cgccgtgctg ctgaacgtcg tgctgcgcct acatggtgct
    12061 gggtgagacg gggcgcgtta tgcgcccttt ttttcgccct tcgcctggcg tgccttgcgc
    12121 cggaatgcct tgatctctgt caggcgggct ttggcgtttt cggcctcctc cggggttgct
    12181 ggttcggtgg ggttgccgtc caggtcgtag cgcatgcact ggtcgatgag gctctgctgg
    12241 tacgagctcg tacccgtgac aatgcccagg atgcgacgga cggctttgcg gtctgcctct
    12301 ggcggcatgt tcagctctgc gcctcgggtc aggatctgct cgatgatgcc ctttgccatg
    12361 gggcgacggt caactccccg ggtcagcaag tcaggccagt gctctttcag gaatgctttg
    12421 gtcacccggt tggccagcgc ctttttggac ttgttggcga tcgcgatgtc ctgctggcgg
    12481 cggtcgttct cctcctgtct gcggatcccc tcggcgacct gttcaggcgt ctttttcggc
    12541 tttgccgctg tgggcttctg tgcgggcttc tgcggggctt tcgcttttgg ctgtaccttc
    12601 gccttgctgg tagtccgttc ggctggctgc ggctcagatt tcgcggcctt ttccggcggg
    12661 acgtagaccg tgcggttgcg tcgcttgatg gtcaggatcg gacgggtggt ttcggtcata
    12721 aatctctctc tggtcggttg gtccggatgt ggtcggcaag ggcgatcagg gtggcggcgt
    12781 cgccgcggtt ccgatcgatg cgccggatga tgtcgttgat gtagtcccag cgcccgacgg
    12841 cggcaaggac ggaaagggcg aggcggttga accggctct
//
