LOCUS       NZ_OX291537            12879 bp    DNA     circular CON 03-SEP-2023
DEFINITION  Serratia marcescens strain SJC1043 plasmid 2, complete sequence.
ACCESSION   NZ_OX291537
VERSION     NZ_OX291537.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA13201010
            Assembly: GCF_946406265.1
KEYWORDS    RefSeq.
SOURCE      Serratia marcescens
  ORGANISM  Serratia marcescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Serratia.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (11-AUG-2022) WELLCOME SANGER INSTITUTE, Pathogen
            Informatics, Wellcome Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/02/2023 07:40:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,241
            CDSs (total)                      :: 5,110
            Genes (coding)                    :: 5,039
            CDSs (with protein)               :: 5,039
            Genes (RNA)                       :: 131
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 19
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 43 of 72
            Pseudo Genes (internal stop)      :: 15 of 72
            Pseudo Genes (multiple problems)  :: 11 of 72
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OX291537.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12879
                     /organism="Serratia marcescens"
                     /mol_type="genomic DNA"
                     /strain="SJC1043"
                     /serovar="NA"
                     /isolation_source="Bloodstream"
                     /db_xref="taxon:615"
                     /plasmid="2"
     gene            join(12279..12879,1..689)
                     /locus_tag="N4J63_RS26085"
     CDS             join(12279..12879,1..689)
                     /locus_tag="N4J63_RS26085"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_157698538.1"
                     /translation="MNDDNDTTEATQPSTEALKCVGAAERFPDIMPGVLFVTCPGGCSL
                     RVEACRQIYEQSHLDRTIENPHLECHRCPTGLALWVGTEQPPDAPLTTPADTRKLCPRC
                     SRKDNRLIAPNKPGSSLCVSCWNREREATIGANARGRVNRTPPFVSPFLIGIGDGWQVW
                     YGIHQGEALVRAMRANPGARFHDRRPGPVGQTRRDGFVYYCPEHREPLRWNGGDGHAGE
                     VELACPRCQPWAAPLSVAPTFQTVSFQTPHDAAHQYRNATLPDNAVWTSSVCADCKAAP
                     LVISKAPVKGKPRREIVVSCPSCDSSASARPGGRTWTDEHIAVPEFAQNETRSLAKIPV
                     ILPQGEQPQLLKRPGTGRGPGRPRKRIPLTLDRVPESRFNRLALSVLAAVGRWDYINDI
                     IRRIDRNRGDAATLIALADHIRTNRPERDL"
                     /name="hypothetical protein"
     gene            686..1327
                     /locus_tag="N4J63_RS26090"
                     /old_locus_tag="SAMEA13201010_05185"
     CDS             686..1327
                     /locus_tag="N4J63_RS26090"
                     /old_locus_tag="SAMEA13201010_05185"
                     /inference="COORDINATES: protein motif:HMM:NF016255.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_070559060.1"
                     /translation="MTETTRPILTIKRRNRTVYVPPEKAAKSEPQPAERTTSKAKVQPK
                     AKAPQKPAQKPTAAKPKKTPEQVAEGIRRQEENDRRQQDIAIANKSKKALANRVTKAFL
                     KEHWPDLLTRGVDRRPMAKGIIEQILTRGAELNMPPEADRKAVRRILGIVTGTSSYQQS
                     LIDQCMRYDLDGNPTEPATPEEAENAKARLTEIKAFRRKARQAKGEKKGA"
                     /name="ProQ/FINO family protein"
     gene            complement(1485..1841)
                     /locus_tag="N4J63_RS26095"
     CDS             complement(1485..1841)
                     /locus_tag="N4J63_RS26095"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559062.1"
                     /translation="MPRHLQGKTRMPLAGGCYSAGHRLALISLLPVLEARPGDRDDGER
                     SKLALYQESLIKAGQPHAFALHEPSLYRWGAYLKSRRARYLQETDAGVAAASDALDRHA
                     FGRAIGAVLGADDE"
                     /name="hypothetical protein"
     gene            complement(1847..2230)
                     /locus_tag="N4J63_RS26100"
                     /old_locus_tag="SAMEA13201010_05186"
     CDS             complement(1847..2230)
                     /locus_tag="N4J63_RS26100"
                     /old_locus_tag="SAMEA13201010_05186"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559064.1"
                     /translation="MSAFSMLCDRLRHEATLAKSTGAGDALAQVLETGGAAQTFAPIGA
                     PVASPTESVHRARAQSIQDAAFLTEMKQAGVAPADLVMLDGVLASSRGLPDASRAPAFA
                     AVRAQVQQQASLSPAARGINWDE"
                     /name="hypothetical protein"
     gene            complement(2231..2887)
                     /locus_tag="N4J63_RS26105"
                     /old_locus_tag="SAMEA13201010_05187"
     CDS             complement(2231..2887)
                     /locus_tag="N4J63_RS26105"
                     /old_locus_tag="SAMEA13201010_05187"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879883.1"
                     /translation="MTEIKTECPDATWLRTTLAEMASDHFPVYDLPCLSVDPNSSAQLT
                     ALDDRRVAREMRQAAADVETRRIDAARVVEGLRTEAERLRGLIADGKTALRAGETVSPD
                     AGVAAFLLPDIEAELVAAEAAEADVARERDALLQDADRRDAAAAIGLFNLAHAVRVQRI
                     EQLLKLAMDEATLLAESDAGRSLYRTVINPDRRLNQLFSTQGAIEILRRNRGMEA"
                     /name="hypothetical protein"
     gene            3147..3734
                     /locus_tag="N4J63_RS26110"
                     /old_locus_tag="SAMEA13201010_05188"
     CDS             3147..3734
                     /locus_tag="N4J63_RS26110"
                     /old_locus_tag="SAMEA13201010_05188"
                     /inference="COORDINATES: protein motif:HMM:NF012464.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_181654175.1"
                     /translation="MSKTYGYVRVSTDEQTSNSQRDAIIARFPTASILADDGISGTVPP
                     RERPALGILLNQILQEGDTLVIYAIDRIGRNARDALELVEELEKRKVTLVSIREGVDLS
                     SAVGQAVLGIMASFAQMERKLILERQAAGIEAAKSRGQKFGRPTKIGAKEAGEIVMRRA
                     MGVPIATIAKQLNLSRSAIYRHLEKVDAVAPE"
                     /name="recombinase family protein"
     gene            3845..4030
                     /locus_tag="N4J63_RS26115"
                     /old_locus_tag="SAMEA13201010_05189"
     CDS             3845..4030
                     /locus_tag="N4J63_RS26115"
                     /old_locus_tag="SAMEA13201010_05189"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879885.1"
                     /translation="MINQAATPRYPGLSIEHGEIRQFGKPRHCAANRKGQYQTTLRDSA
                     GRYQTVSIISLYAWEA"
                     /name="hypothetical protein"
     gene            4149..4394
                     /locus_tag="N4J63_RS26120"
                     /old_locus_tag="SAMEA13201010_05190"
     CDS             4149..4394
                     /locus_tag="N4J63_RS26120"
                     /old_locus_tag="SAMEA13201010_05190"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558916.1"
                     /translation="MAFENIPRRFQRWKVIMVPGAKSYESWDEMVTGENFSEETRMKTY
                     KKHRTKAIDRTVANQEYIHTMTEDGITVRYRLERWR"
                     /name="hypothetical protein"
     gene            4593..5060
                     /locus_tag="N4J63_RS26125"
                     /old_locus_tag="SAMEA13201010_05191"
     CDS             4593..5060
                     /locus_tag="N4J63_RS26125"
                     /old_locus_tag="SAMEA13201010_05191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324036.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_070559148.1"
                     /translation="MKKYTTEQKAQALRLLEQDGATAATVARTMGIPPRTVRDWAKART
                     DAPSNVLSIEEMRERAQRAVEATPQAAIRRLKNHFVQRQFELLQRHATDLQALRTASLQ
                     AMLEKDATMVKAISGLMTSLLKTQERERVIYEIKPGTEADIMREGMNRQQS"
                     /name="transposase"
     gene            complement(5706..7001)
                     /locus_tag="N4J63_RS26130"
                     /old_locus_tag="SAMEA13201010_05192"
     CDS             complement(5706..7001)
                     /locus_tag="N4J63_RS26130"
                     /old_locus_tag="SAMEA13201010_05192"
                     /inference="COORDINATES: protein motif:HMM:NF017116.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="WP_119879886.1"
                     /translation="MSQIDENSGTAADNVTPIAAAKVGRPSLQKKYPTTAFPVELEINY
                     RKGRYSSSLENVVAAMRCHSVTGIQLAFDEFFAEEGAFVNGQWYPLSDNLVTELRLRLA
                     AADFEKVTKDNARDAMFYVCDENKFDSAQRWLTAQEWDGKPRVSYFFERCFKCQGDPEY
                     LAAVSLYTWTALAGRVMNPGIKADMVPLLYGRQGARKSTGVRLMSPFPDSYSSFNLNDK
                     DDSLVRRMRGCLIGELEELRGLHGRDSESVKAFFSAAHDEWVPKFKEFKVRNPRRVVFI
                     GTTNNKQILNDSTGNRRYLPMNSGDVDCAAIEKNRSQLWAEALHLFNENGVMWEAAETL
                     ARKVHDEFRVEDPWEDEIAELLKLDVDDCDPTAFVPTKALFSQVGLMIGHTSNKQHQRM
                     AAIMSRLGYEVGRKRINGALVRGYFRRTQAVV"
                     /name="VapE domain-containing protein"
     gene            7529..8020
                     /locus_tag="N4J63_RS26135"
     CDS             7529..8020
                     /locus_tag="N4J63_RS26135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558888.1"
                     /translation="MREKTKTLTVRLPVSLIERIEQNAARTGATRTDAVIEALNAGLGT
                     KPEGMDTKLLAAIEALRAEVRALSVGGKPARQTAQQTAPQSAQQPARQIVPRGADPRFQ
                     AVSDEADQLIVSMTAENATLPAIASALNAAGHRTATGQEWNTSRVRDYRHKLRESGLLN
                     "
                     /name="hypothetical protein"
     gene            8085..8576
                     /locus_tag="N4J63_RS26140"
     CDS             8085..8576
                     /locus_tag="N4J63_RS26140"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351425.1"
                     /translation="MAIGDDAIRDAFYAFTQQAEEMDDKGLPQEVWETPCFTYLMTKKQ
                     FNQMKVVCQRNGWDIPASPAIPITWAMFRHVLSARNSKDKLSWQECAEILATAFSVQSN
                     VYVNRDYSEQTIVLNAVRRINVAGAGFFAMAIVDVSENNLAPVTAYHATEAKCKAIQRG
                     "
                     /name="hypothetical protein"
     gene            9023..9607
                     /locus_tag="N4J63_RS26145"
                     /old_locus_tag="SAMEA13201010_05194"
     CDS             9023..9607
                     /locus_tag="N4J63_RS26145"
                     /old_locus_tag="SAMEA13201010_05194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004589499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351424.1"
                     /translation="MDITISDATYSRLAAQAKGFETPEQVINRLIDVVEIDHDTRPELF
                     FNPEGEADFKKALLKSKQAKVEMFKRDGSCETGVWNARAISEESSVRANIWSGYLRGWK
                     EKGIVRAVFTVQEVPDLPGAAESVQWNDYTISRTFSGGISVQRNGMPVTIVKPFLRDVA
                     HDLKISLLNSNGNEMNTRQLGAAIIKKLNNS"
                     /name="hypothetical protein"
     gene            complement(9862..10320)
                     /locus_tag="N4J63_RS26150"
                     /old_locus_tag="SAMEA13201010_05195"
     CDS             complement(9862..10320)
                     /locus_tag="N4J63_RS26150"
                     /old_locus_tag="SAMEA13201010_05195"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765952.1"
                     /translation="MKSKTELREAATARSLAVIATEMSEWSLDGFSHLKLPNFSAGERQ
                     QTLSGSVVVDRPPFDYEWAGTEKFNTLATRALQVKLPASRERNYAWLCGVERETLATAL
                     LVELFSVTGCVAFAGLGKVADLAFLTLDESEAGQIRAAMLQWLDGAAA"
                     /name="hypothetical protein"
     gene            complement(10546..11727)
                     /locus_tag="N4J63_RS26155"
                     /old_locus_tag="SAMEA13201010_05196"
     CDS             complement(10546..11727)
                     /locus_tag="N4J63_RS26155"
                     /old_locus_tag="SAMEA13201010_05196"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765953.1"
                     /translation="MAFDNSHLTDAGLFWRAVSAAGAPVDREDWLRLCSGIACWASLCG
                     EDGLAAIEAWSTRHNRGSAHHRSQYRHFLKLKGVTNPEAMAQVFLRFSGEVYWRLDSNR
                     TPPSTEQVAALAERKRRSIEAVARREDADRRKADKAAADAVRMLAKGDGNPAYTPYWRN
                     KTTIARRGGVSLPPLPADLRVGGLFRSFEPRAYWSRCLLVPAYRLTDDRQLVGDALEAI
                     CGVCSAGGKTGDKFSPAGTQKAGRFYPMPGFMDVLDTSPHAPYSPLFVCEGFATAVALH
                     HLTKGKVAVCAAFSIAGFGSCVASLRRFWPDVDVMLVPDHGEAYRLAHKAAYGDEREPV
                     PTIPGAAVVSFDGLDRFTPRDNLDWFDVLVEEGEDRARELLRYAVRHARLERR"
                     /name="hypothetical protein"
     gene            complement(11714..11923)
                     /locus_tag="N4J63_RS26160"
     CDS             complement(11714..11923)
                     /locus_tag="N4J63_RS26160"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765954.1"
                     /translation="MKKRIYTADLAALLNVSLRTLSRLSSRGIVPTPAGRSLRGGHYWL
                     AGDPVLKRFIADQRRPGRAPYGVR"
                     /name="hypothetical protein"
ORIGIN
        1 tgtactactg ccccgaacac cgcgagcccc tgcgctggaa cggtggcgac gggcacgccg
       61 gagaggtgga gcttgcttgt cccaggtgcc agccatgggc ggcacctctc agcgtcgccc
      121 ccacgtttca gacggtcagc ttccagacac cgcatgacgc cgcgcaccag taccggaacg
      181 ccaccctgcc agacaacgcg gtctggacat cgtcggtctg cgctgattgc aaagccgcgc
      241 ccctggtgat cagcaaggca ccggtcaagg gcaagccgcg acgggagatc gtcgtctcct
      301 gcccgtcctg cgactccagc gcatcagcca ggcccggagg caggacatgg acagacgagc
      361 acatcgcggt gcccgagttc gcgcagaacg agacgcgcag cctggcgaag atccccgtta
      421 ttttgccgca gggggagcag ccgcagctgc tcaaaagacc agggacaggg cgcggtccag
      481 gacgcccccg caagcgcatc cccctgaccc tcgaccgggt accagagagc cggttcaacc
      541 gcctcgccct ttccgtcctt gccgccgtcg ggcgctggga ctacatcaac gacatcatcc
      601 ggcgcatcga tcggaaccgc ggcgacgccg ccaccctgat cgcccttgcc gaccacatcc
      661 ggaccaaccg accagagaga gatttatgac cgaaaccacc cgtccgatcc tgaccatcaa
      721 gcgacgcaac cgcacggtct acgtcccgcc ggaaaaggcc gcgaaatctg agccgcagcc
      781 agccgaacgg actaccagca aggcgaaggt acagccaaaa gcgaaagccc cgcagaagcc
      841 cgcacagaag cccacagcgg caaagccgaa aaagacgcct gaacaggtcg ccgaggggat
      901 ccgcagacag gaggagaacg accgccgcca gcaggacatc gcgatcgcca acaagtccaa
      961 aaaggcgctg gccaaccggg tgaccaaagc attcctgaaa gagcactggc ctgacttgct
     1021 gacccgggga gttgaccgtc gccccatggc aaagggcatc atcgagcaga tcctgacccg
     1081 aggcgcagag ctgaacatgc cgccagaggc agaccgcaaa gccgtccgtc gcatcctggg
     1141 cattgtcacg ggtacgagct cgtaccagca gagcctcatc gaccagtgca tgcgctacga
     1201 cctggacggc aaccccaccg aaccagcaac cccggaggag gccgaaaacg ccaaagcccg
     1261 cctgacagag atcaaggcat tccggcgcaa ggcacgccag gcgaagggcg aaaaaaaggg
     1321 cgcataacgc gccccgtctc acccagcacc atgtaggcgc agcacgacgt tcagcagcac
     1381 ggcgagcagc tgcgacacgt tgcgcgatcc ccctggcctt tcgcgcagca acaaccccgt
     1441 cagggatcac cacctcaggg atgaccagac gcgagacggc aaactcactc atcatcagcc
     1501 cccaggaccg caccaatagc acgcccgaaa gcatgccgat caagcgcgtc tgaggccgca
     1561 gcaacacctg cgtctgtctc ctgtaaatac cgggcgcggc ggctcttcag atacgccccc
     1621 cagcgataca gcgacggctc atgtaacgcg aacgcgtgcg gttgcccggc cttgatcagc
     1681 gattcctgat acagcgccag cttcgatcgt tcaccatcat ccctgtcacc aggacgagcc
     1741 tccagaacag gcagcaacga gatcagcgca agacggtggc cagcagagta acaaccacct
     1801 gccagcggca tccgcgtctt accctgcagg tggcgcggca tcggctttac tcgtcccaat
     1861 tgataccccg ggcagcaggg gagagagacg cctgttgctg cacctgagca cgcaccgcag
     1921 cgaacgccgg agcacgcgac gcatcaggga gtccgcgaga ggaggccagc acgccgtcaa
     1981 gcatcaccag atcggcagga gccacgcccg cctgtttcat ctcagtcagg aacgccgcat
     2041 cctggatgga ctgagcacgc gcccggtgaa ccgactccgt aggagaggca accggagccc
     2101 cgatcggcgc gaacgtctgc gcagcaccgc ccgtctccag cacctgcgcc agcgcgtcgc
     2161 cggccccggt agattttgcc agcgtcgcct catggcgaag ccggtcacac agcatcgaaa
     2221 atgcagacat ttacgcctcc atgccgcgat tgcggcgcag aatttcgatc gcaccctgcg
     2281 tggagaacag ctggttcagg cggcgatcag gattgataac agtacggtac aaactgcgcc
     2341 ccgcgtcgga ctcggcaagc agcgtcgcct catccatcgc cagcttcagc agctgctcaa
     2401 tacgctgtac gcgcacggcg tgcgccaggt tgaacaggcc gatcgcagcc gccgcatcac
     2461 ggcggtcagc atcctgcagc agcgcgtcac gctcccgggc cacatcagcc tcagcagcct
     2521 cggcggcaac cagctcggcc tcgatatccg gcagcaggaa cgcagcgacg cccgcatcgg
     2581 ggctcacagt ctcgccagca cgcagcgccg tcttgccgtc ggcaatcagc ccgcgcaggc
     2641 gttcagcttc cgtcctgagc ccttccacca cgcgagcggc gtcaatgcgt cgcgtttcca
     2701 cgtcggctgc tgcctgacgc atttcacgcg ccacccggcg atcgtcaagc gcggtaagtt
     2761 gagcggagga gttaggatcc accgacaggc aaggaaggtc ataaacggga aaatggtcac
     2821 tcgccatttc agcaagcgtg gtacgcagcc aggtcgcgtc cgggcattcg gttttgattt
     2881 cggtcatggt ttggttctca gcaagttatc agcaaagcgg cagcaaacgc cgctcagaca
     2941 gcatgccgtc acgacaccgc gcagacatca acgcagaggg cgcagggctc tcgcccagcg
     3001 cggagagccg cctggaggcc gtcgctaatc ccctacattc cgggacaccc gacaaagcga
     3061 cgaaatagac actttagcga tagactttcg gtacagttgt ggcatgttgt gtcgaaagag
     3121 acgtatcggt cagaggagag aaaaaagtga gcaaaacata cggttacgtt cgcgtatcaa
     3181 ccgacgaaca aaccagcaac agccagcgcg acgccatcat cgcccggttc ccaacagcct
     3241 ccatcctcgc cgacgacggg atcagcggga cggtaccacc acgcgagcgt ccagccctcg
     3301 gcatcctcct gaaccagatc ctgcaggagg gcgacacgct ggtcatctac gcgatcgacc
     3361 gcatcggcag gaacgcccgg gacgccctcg aactggtcga ggagctggag aaacgaaaag
     3421 taaccctggt cagcatccgc gagggtgtcg atttgagcag cgccgtcgga caggccgtcc
     3481 tcggcatcat ggcgagtttc gcgcagatgg agcgcaagct catactggaa cgccaggcgg
     3541 cagggatcga ggccgcaaag agccgtggcc agaagttcgg acgcccgacc aagatcggcg
     3601 cgaaagaagc gggggagata gtcatgcgcc gcgccatggg ggtaccaata gccaccatag
     3661 ccaagcagtt aaatctgagc aggagcgcga tttaccgcca ccttgagaag gtcgacgcgg
     3721 tagcgccgga gtaagagaga gcgcagcggt gtaggtggct ccaaccattc cacaccgccg
     3781 caacccagcc cggggaacgc atgaggagca gacccgggca ccattcccaa caaggaacag
     3841 aaccatgata aaccaagcag caacaccgcg ctatcccggc ctgagcattg aacacggcga
     3901 gatccgccag ttcggcaagc cccgccattg cgccgccaac cgcaaaggcc agtaccagac
     3961 caccctccgc gacagcgccg gtcggtacca gacagtcagc atcatcagcc tttacgcctg
     4021 ggaagcatga ccataacgaa agccttacag gtgtaagcag caagcaataa caaaagcctt
     4081 acgccattac gaaccactta caggggcgcg ggagcgcccc cagaaaccag aatcataagg
     4141 agagaacgat ggcatttgaa aacattcccc gtaggttcca gagatggaag gtaatcatgg
     4201 ttcccggagc aaagtcatat gagtcatggg acgagatggt taccggcgag aacttctccg
     4261 aagaaaccag gatgaaaacg tacaaaaagc accgcaccaa ggccatcgac cgcaccgtgg
     4321 caaaccagga gtacatccat accatgacgg aggacgggat caccgtcagg taccgcctcg
     4381 aacgctggcg ctaaccccag ctaggagcgc agcgactgct gcgcctcctc ccttacccag
     4441 aacgcaccag agccattcta agcgcctcag ccacaaaaat acccaaccgc acgaccacgc
     4501 acgcacaaac gccgtgtacc ccccaaaaac ccccgccatt ttcagcgcgt gacgtttcaa
     4561 tacaggagag aaaccaaccg gagcaggaca ccatgaagaa atacaccacc gagcagaaag
     4621 cccaggcgct cagactactg gagcaggacg gcgcaaccgc agccaccgtc gcacgcacca
     4681 tggggatccc accccgcacc gtcagagatt gggcgaaagc ccgcaccgac gcacccagca
     4741 acgtcctcag catcgaggag atgcgcgaac gcgcacagcg agccgtcgag gccaccccac
     4801 aggcagcgat ccgacgccta aaaaaccact ttgtacagcg ccagtttgag ctgctacagc
     4861 gccacgccac cgacctgcaa gccctccgca cagcttcgct acaggccatg ctggagaagg
     4921 acgccaccat ggtcaaagcg atcagcggcc ttatgacatc cctactcaag acgcaggaac
     4981 gcgagcgcgt catctacgag atcaagccag gcaccgaggc cgacatcatg cgcgagggca
     5041 tgaatcgcca acagagctga aaacggcggg aaaaccgcct tttaccgccg ctttaccgcc
     5101 gcagaaaacc cgggagcccg cgaaatacgc ggatccgcac gttaacgagt tgttaccgct
     5161 cgcgtgcgcg agggcaagcc ctcacgcaga accaacagac gaccacccag cgcgaggcga
     5221 aagcctcgtg ccctcagcgc cacccaaacc tccgatcccc ctcagaacca ctaccaccga
     5281 ccatcccggc acgacgaacc catccaccga tctaataaga caagcaaagt gcatccggca
     5341 gggtgcagct gcggcgcgtc gattccaaga tgatccaccc gttccacccg atccggcata
     5401 gattcataaa tagtaaaaaa aacaactaat tgttcaatta gtgagcattt accccctatt
     5461 tacccaattt attcattttt tgtttttaat tagaaaatag ggtggaacgg gtggaacaca
     5521 acaatgaaag cctttaaaca cgaggcctta gctgttccat ccacgggcgg aacacgggtg
     5581 gaacgggtgg aacacccggg tggaacaggt ggtacaaaaa cggcgtgatg atccacccgt
     5641 gatccacccg ggtggaacaa taaaaaaggg gagcatatag ctcccctctt acggaaaagt
     5701 aacccttaca cgacagcttg cgttcgacgg aagtagccac gaactaacgc accgtttatg
     5761 cgcttcctgc caacctcata gcccaatcgg gacatgatag ccgccatgcg ctgatgctgc
     5821 ttgttgctgg tatggccaat catgagccct acctgagaga acaaggcctt cgtcggcacg
     5881 aaagcagtcg ggtcgcagtc gtcaacgtcc agcttgagca gctcggcgat ctcgtcttcc
     5941 cacggatcct cgacgcggaa ctcgtcatgc accttacgcg ccagcgtttc agcggcctcc
     6001 cacatcaccc cattctcatt gaacaggtgg agcgcttcag cccacagctg cgagcggttt
     6061 ttctcgatgg ccgcgcagtc cacgtccccg gaattcatgg gcaaatagcg gcggttcccc
     6121 gtcgagtcat tgaggatctg cttgttgttc gtggtaccga tgaacaccac gcggcgcggg
     6181 tttcgcacct tgaactcttt aaatttcggc acccactcgt cgtgggcagc ggagaagaac
     6241 gctttcaccg attcggagtc gcgcccgtgg aggccgcgca gctcctccag ctcgccaatc
     6301 aggcacccac gcatacggcg cactagggag tcgtccttgt cgttcaggtt gaagctggag
     6361 taggagtcag ggaatggcga cataaggcga acgcccgtcg atttgcgggc accctgtcgc
     6421 ccgtacagca gcggaaccat gtcggccttg attccgggat tcattacgcg cccggcaagc
     6481 gccgtccagg tgtagaggct gaccgccgcc aggtactcgg gatccccttg gcatttgaag
     6541 caccgctcga agaagtaact gacgcgaggt ttgccgtccc attcctgagc cgtcagccaa
     6601 cgctgggcgc tgtcgaattt gttctcatcg cagacgtaga acatggcgtc gcgggcattg
     6661 tccttggtca ccttctcgaa gtcggcagca gcgaggcgca gacgcagctc ggtaactagg
     6721 ttgtcggaca gcgggtacca ttgcccgttc acgaacgccc cctcctccgc aaagaactca
     6781 tcgaaagcga gctggatgcc ggtgacggaa tggcagcgca tagcggcgac aacgttctca
     6841 agagaggacg agtagcgccc cttccggtag ttgatctcca gctccacggg aaacgcggta
     6901 gtcgggtatt ttttttgtag agacgggcgt cccaccttgg cagcggcgat cggcgttacg
     6961 ttgtcggcag cagtgccgga attttcatca atttgtgaca cgcaattact cctttaaaaa
     7021 cgtaggagtc ggcgtcaggc gggggcttac gagggaaatt cacacttgcg cgatcttatc
     7081 gacgtggtac acttctcttt gagtttgagg agtacgctgc gcaagtgcta ttcttccttc
     7141 gagaacgtcc cgctaagacg tgactcgaat taatcggagg agttaccagc tcccccggca
     7201 gaaaaaggtg accacccaac aggtcgcctt tttttgtgcc cgaagatccc caaccggatc
     7261 cgcagacgcc agatcagctt acccgatccc aaccctccac gccacttagc gccgcgcact
     7321 tatcgcgctg tcgtgatcac gcccagctca atctctgcgc cgcctctgct atttatccat
     7381 gtacacaaac ggcaccccgg cgacgcaaag ccgtcgcccc tctgtgcacg acaactgcac
     7441 gacgtcgaat tcgacgcgca cgacaaaacg cattacacta cgcaagacaa acagcacgac
     7501 aaaacgcacg acgtggagag cagcagccat gagagagaaa accaaaaccc tgaccgttcg
     7561 cctacccgtt agcctgatcg aacgcatcga gcagaacgca gcacgaaccg gagcaacccg
     7621 cacggatgct gtcatagagg cgctgaacgc cggacttggc acgaagccgg aagggatgga
     7681 caccaaactt ttagctgcca tcgaagcgct gagggctgaa gtcagggcgc tgtccgtcgg
     7741 cggtaaacct gcacgacaaa ccgcacaaca aacagcacca caaagcgcac aacaacctgc
     7801 aagacagata gtcccccggg gagccgatcc gcgcttccag gccgtcagtg atgaggctga
     7861 ccagctcatt gtcagcatga ccgcagagaa cgcgactctg cccgccatcg cgtcggcact
     7921 gaacgcagca gggcaccgga cagcgacggg acaggagtgg aacaccagcc gtgtccggga
     7981 ctatcgccat aagttgcggg aaagtgggct actgaattag cagtcctaag tgacatagct
     8041 aaatatgata aaattcgaac ataaaaattt tacaaggaaa agaagtggct atcggtgatg
     8101 atgctatccg tgacgctttc tatgctttta cacagcaagc tgaagaaatg gatgataaag
     8161 gtctccctca ggaagtttgg gagacgcctt gttttaccta tctgatgact aagaagcagt
     8221 tcaatcaaat gaaagttgtt tgtcagagaa acggctggga catacctgca tcaccagcaa
     8281 taccgatcac ttgggcaatg tttaggcatg tgctatctgc tcgtaactcg aaggataagc
     8341 taagttggca agagtgtgcg gagattttgg caactgcatt ctcagtgcag agcaatgtgt
     8401 acgttaacag agattactcg gagcagacta ttgtgctcaa tgctgttcgt cgcattaacg
     8461 ttgctggggc tggctttttc gcaatggcga tagttgatgt ctctgaaaat aatttggccc
     8521 ccgtgactgc ataccatgca acggaggcca aatgtaaagc tatacagcga gggtgatagg
     8581 aaggacgccc atttaagcaa ttctcctcaa tttaatgaga atgaaccata acgcctaaat
     8641 atttcccttc attggttcct ttcggatcta gcagcatcgg cggttttctg ctgtctatca
     8701 aattcactgt tattactagg aagccgcaac ataacttccc aacaggagac cagcctcctg
     8761 actgcccagc gcaaagggtt aattactggt taataccccc tgcgaatgct cttgcagtac
     8821 aacaatagta ggctattgtt gacgtagatt caactggttt gtttataacc aagcggcacg
     8881 aggagcgggt ttacaggttt ttatagctct ttagaggcgg ttaaccatat tgcgatatca
     8941 ggtaattata gatcttgaaa tcattaaatt tatcaattat gattaatttt atgattaatt
     9001 tttgatctat agaggtactt tgatggatat tacgatatct gacgctacat atagccgtct
     9061 tgctgcacaa gcaaagggat ttgaaactcc cgaacaggta ataaaccgtc tgatcgatgt
     9121 tgttgaaatc gatcatgaca cacgccctga actttttttt aatcctgaag gtgaagcgga
     9181 ttttaaaaaa gcgttactaa aatcaaaaca ggccaaagtc gaaatgttta aaagggatgg
     9241 ttcctgtgaa actggagtat ggaatgctcg tgcgatttca gaagaatcat cagttcgggc
     9301 aaatatttgg agtgggtatt tgcgtggatg gaaggaaaaa gggattgttc gtgcggtttt
     9361 cactgtccag gaggttcctg acttgccagg agcggctgaa agtgtgcagt ggaatgatta
     9421 tacaatcagt cgcactttta gtggcggtat ttcagttcaa agaaatggca tgcctgtaac
     9481 tattgtgaag ccatttctac gtgatgttgc gcatgattta aaaatatcat tgctaaatag
     9541 caatggaaat gaaatgaata ctcggcagct tggcgcagcg atcataaaga agttaaataa
     9601 ctcttaacat cgatgcttca cgcagaggag cgacggctca acgccgccgc cggtcagagt
     9661 tctactgcga cgaatacgca ccattcatag ctggcgaggc agaacgcccg ccacctgtca
     9721 tcagacgccc ggtcaacaca ctccagccat aaccgcgccg cagcaaggtg gtcgcagcgc
     9781 accgggtcgc cccgcagttc cgtcgccatg gcctcctcga tcagtcgccc ttcccactcc
     9841 agctgatcga ggatcgagcc cctacgccgc cgccccatcg agccactgca gcatcgccgc
     9901 cctgatctgc cccgcctcgc tctcgtccag cgtcaggaac gccagatcgg caaccttacc
     9961 cagcccggcg aacgccacgc agccggtgac ggagaacagc tccacgagga gcgccgtcgc
    10021 cagcgtctcc cgttcaacgc cgcacaacca ggcgtagtta cgctcacgcg atgccggaag
    10081 tttcacctgc agcgcacggg tggccagagt gttaaatttc tcggtaccag cccactcgta
    10141 gtcgaacggc gggcgatcaa ccaccaccga cccggacagc gtctgctggc gttccccagc
    10201 ggagaagttc ggcagcttga ggtgggagaa cccatcgagc gaccactccg acatttcagt
    10261 ggcgatcacc gccagagagc gagccgtcgc ggcctcgcgt agttcagtct ttgatttcat
    10321 gtgccctcct ttgggctaaa aaaaaacccg acatcaagac gaggccgggc tttatgctgc
    10381 tgtgagaaac cgatcgcagg atagcgtcac gacggcagcg ccggtgcgtc gctttagtcc
    10441 gtctcatcaa aaaagcatcg gtagtgtctc gaaagtcgtt cgctaaacca gacgccacga
    10501 cggcaaaaaa gatgtcccga aaggcgcacc attcggacac gccaatcaac gccgctcaag
    10561 ccgggcatga cgaaccgcgt agcgcagcag ctcacgagcc cgatcttccc cttcctcaac
    10621 cagcacgtcg aaccagtcga ggttatcccg gggcgtgaag cgatcgaggc cgtcgaacga
    10681 cacaaccgcc gcgcctggaa ttgtcgggac cggctctcgc tcatcgccat aggccgcttt
    10741 atgcgccagg cggtacgctt cgccgtgatc cggtaccagc atcacatcaa catctggcca
    10801 gaaccggcgc agcgacgcca cgcagctgcc gaacccggca attgagaacg ccgcgcagac
    10861 tgccaccttg cccttcgtca gatgatgcag ggcaaccgcc gtggcgaacc cctcacagac
    10921 gaacagaggc gagtagggcg catgtggtga ggtatcgagc acgtccataa agccgggcat
    10981 cggatagaac cgtcccgcct tttgggtacc tgcaggggag aacttgtcgc cggttttgcc
    11041 gccagcagag cagacgccgc agatggcctc cagcgcgtcg ccaaccagct ggcgatcatc
    11101 ggtcaggcga taggcaggaa caagcagaca gcgcgaccag tacgccctcg gttcgaacga
    11161 gcggaacaag ccacccacac gaaggtcagc ggggaggggc gggaggctga cgccaccacg
    11221 cctggcgatt gtggtcttat tgcgccagta cggggtatag gccggattac cgtcgccttt
    11281 cgccagcatc ctgaccgcat cagccgcagc cttatcggcc ttgcgccggt cggcatcttc
    11341 gcgtctggcc accgcctcga tcgatcggcg tttccgttca gcaagagcag caacctgttc
    11401 agtcgacggc ggcgtgcgat ttgagtcgag ccgccagtac acctcgcctg agaaccgcag
    11461 gaatacttgc gccatggcct cgggattggt tacgcctttc agcttcagga agtgccggta
    11521 ctgcgaccgg tgatgcgcag atccgcgatt gtggcgggta gaccaggcct cgatagcagc
    11581 aagcccgtcc tctccgcaga gagatgccca gcatgcgatg ccagaacaga ggcgcagcca
    11641 gtcctcgcgg tcaaccggag ccccagccgc agagacggca cgccagaaca ggccagcgtc
    11701 agtcaggtga gagttatcga acgccataag gagccctccc gggacgacgc tggtcggcaa
    11761 taaagcgttt gagcacggga tccccagcca gccagtaatg cccgccacga agggaacgcc
    11821 ctgccggagt cggaacgatc ccccgcgaac tcaggcggga gagcgtgcgc agcgacacgt
    11881 tcagcagcgc agcgaggtca gcggtataga ttcgtttttt cattgggagt accagatagg
    11941 tgcccccctc agcttaacgg gcatcggggg gcgggagtga cgattatcga taaagccgcc
    12001 cttgaggact taccgcatag cggcaggaca gcagcccttc tcgcttactc gcacctgcca
    12061 aggacgaagc gcgcatcctc gtttacaacc ccgcctcgtt ggggaggagg gaaagcggca
    12121 ccgggcgatc cggtttcatg tttcccaact gctcgtcagg aatcagtaag acaagcttaa
    12181 cacaattaac gccaaagtgg cgttttttgt gagatactaa aaaagacgca cagccagtgc
    12241 tggcgaggtc tggcgaccat ttcgacgcag ggggagcagt gaacgacgat aacgacacga
    12301 cagaagcgac gcagccgtca accgaggcac tgaagtgcgt aggcgctgcg gagcggttcc
    12361 ccgacatcat gcccggcgtt ttgttcgtca cctgccccgg cgggtgctcc ctccgggtcg
    12421 aggcatgccg acagatttat gagcagagcc acctcgatcg cacgattgaa aacccccacc
    12481 tcgagtgcca ccggtgcccc actggcctcg cgctttgggt cggtaccgaa cagccccctg
    12541 acgcaccact gaccaccccg gcagacaccc gtaagctctg cccccgttgc agccggaaag
    12601 acaaccgcct gatcgccccc aataagcccg gttcgagcct gtgcgtctcc tgctggaacc
    12661 gcgaacgcga agccaccatc ggagccaacg cacgcgggag agtcaaccgc accccaccgt
    12721 tcgtctcgcc gttcctgatc ggcatcggcg atggctggca ggtctggtac ggcatccacc
    12781 agggcgaggc gctcgtccgc gccatgcgag ccaacccggg cgcacggttc cacgatcgcc
    12841 gaccaggccc ggtcgggcaa acacgccgcg acggtttcg
//
