LOCUS       NZ_OX291476            12869 bp    DNA     circular CON 03-SEP-2023
DEFINITION  Serratia marcescens strain SJC1062 plasmid 3, complete sequence.
ACCESSION   NZ_OX291476
VERSION     NZ_OX291476.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA13201030
            Assembly: GCF_946404965.1
KEYWORDS    RefSeq.
SOURCE      Serratia marcescens
  ORGANISM  Serratia marcescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Serratia.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (11-AUG-2022) WELLCOME SANGER INSTITUTE, Pathogen
            Informatics, Wellcome Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/02/2023 08:01:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,396
            CDSs (total)                      :: 5,266
            Genes (coding)                    :: 5,186
            CDSs (with protein)               :: 5,186
            Genes (RNA)                       :: 130
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 19
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 32 of 81
            Pseudo Genes (incomplete)         :: 51 of 81
            Pseudo Genes (internal stop)      :: 13 of 81
            Pseudo Genes (multiple problems)  :: 12 of 81
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OX291476.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12869
                     /organism="Serratia marcescens"
                     /mol_type="genomic DNA"
                     /strain="SJC1062"
                     /serovar="NA"
                     /isolation_source="Bloodstream"
                     /db_xref="taxon:615"
                     /plasmid="3"
     gene            complement(112..603)
                     /locus_tag="N4J64_RS26815"
     CDS             complement(112..603)
                     /locus_tag="N4J64_RS26815"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351425.1"
                     /translation="MAIGDDAIRDAFYAFTQQAEEMDDKGLPQEVWETPCFTYLMTKKQ
                     FNQMKVVCQRNGWDIPASPAIPITWAMFRHVLSARNSKDKLSWQECAEILATAFSVQSN
                     VYVNRDYSEQTIVLNAVRRINVAGAGFFAMAIVDVSENNLAPVTAYHATEAKCKAIQRG
                     "
                     /name="hypothetical protein"
     gene            complement(668..1159)
                     /locus_tag="N4J64_RS26820"
     CDS             complement(668..1159)
                     /locus_tag="N4J64_RS26820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558888.1"
                     /translation="MREKTKTLTVRLPVSLIERIEQNAARTGATRTDAVIEALNAGLGT
                     KPEGMDTKLLAAIEALRAEVRALSVGGKPARQTAQQTAPQSAQQPARQIVPRGADPRFQ
                     AVSDEADQLIVSMTAENATLPAIASALNAAGHRTATGQEWNTSRVRDYRHKLRESGLLN
                     "
                     /name="hypothetical protein"
     gene            1687..2982
                     /locus_tag="N4J64_RS26825"
                     /old_locus_tag="SAMEA13201030_05337"
     CDS             1687..2982
                     /locus_tag="N4J64_RS26825"
                     /old_locus_tag="SAMEA13201030_05337"
                     /inference="COORDINATES: protein motif:HMM:NF017116.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="WP_119879886.1"
                     /translation="MSQIDENSGTAADNVTPIAAAKVGRPSLQKKYPTTAFPVELEINY
                     RKGRYSSSLENVVAAMRCHSVTGIQLAFDEFFAEEGAFVNGQWYPLSDNLVTELRLRLA
                     AADFEKVTKDNARDAMFYVCDENKFDSAQRWLTAQEWDGKPRVSYFFERCFKCQGDPEY
                     LAAVSLYTWTALAGRVMNPGIKADMVPLLYGRQGARKSTGVRLMSPFPDSYSSFNLNDK
                     DDSLVRRMRGCLIGELEELRGLHGRDSESVKAFFSAAHDEWVPKFKEFKVRNPRRVVFI
                     GTTNNKQILNDSTGNRRYLPMNSGDVDCAAIEKNRSQLWAEALHLFNENGVMWEAAETL
                     ARKVHDEFRVEDPWEDEIAELLKLDVDDCDPTAFVPTKALFSQVGLMIGHTSNKQHQRM
                     AAIMSRLGYEVGRKRINGALVRGYFRRTQAVV"
                     /name="VapE domain-containing protein"
     gene            complement(3628..4095)
                     /locus_tag="N4J64_RS26830"
                     /old_locus_tag="SAMEA13201030_05338"
     CDS             complement(3628..4095)
                     /locus_tag="N4J64_RS26830"
                     /old_locus_tag="SAMEA13201030_05338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324036.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_070559148.1"
                     /translation="MKKYTTEQKAQALRLLEQDGATAATVARTMGIPPRTVRDWAKART
                     DAPSNVLSIEEMRERAQRAVEATPQAAIRRLKNHFVQRQFELLQRHATDLQALRTASLQ
                     AMLEKDATMVKAISGLMTSLLKTQERERVIYEIKPGTEADIMREGMNRQQS"
                     /name="transposase"
     gene            complement(4294..4539)
                     /locus_tag="N4J64_RS26835"
                     /old_locus_tag="SAMEA13201030_05339"
     CDS             complement(4294..4539)
                     /locus_tag="N4J64_RS26835"
                     /old_locus_tag="SAMEA13201030_05339"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558916.1"
                     /translation="MAFENIPRRFQRWKVIMVPGAKSYESWDEMVTGENFSEETRMKTY
                     KKHRTKAIDRTVANQEYIHTMTEDGITVRYRLERWR"
                     /name="hypothetical protein"
     gene            complement(4658..4843)
                     /locus_tag="N4J64_RS26840"
                     /old_locus_tag="SAMEA13201030_05340"
     CDS             complement(4658..4843)
                     /locus_tag="N4J64_RS26840"
                     /old_locus_tag="SAMEA13201030_05340"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879885.1"
                     /translation="MINQAATPRYPGLSIEHGEIRQFGKPRHCAANRKGQYQTTLRDSA
                     GRYQTVSIISLYAWEA"
                     /name="hypothetical protein"
     gene            complement(4954..5541)
                     /locus_tag="N4J64_RS26845"
                     /old_locus_tag="SAMEA13201030_05341"
     CDS             complement(4954..5541)
                     /locus_tag="N4J64_RS26845"
                     /old_locus_tag="SAMEA13201030_05341"
                     /inference="COORDINATES: protein motif:HMM:NF012464.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_181654175.1"
                     /translation="MSKTYGYVRVSTDEQTSNSQRDAIIARFPTASILADDGISGTVPP
                     RERPALGILLNQILQEGDTLVIYAIDRIGRNARDALELVEELEKRKVTLVSIREGVDLS
                     SAVGQAVLGIMASFAQMERKLILERQAAGIEAAKSRGQKFGRPTKIGAKEAGEIVMRRA
                     MGVPIATIAKQLNLSRSAIYRHLEKVDAVAPE"
                     /name="recombinase family protein"
     gene            5801..6457
                     /locus_tag="N4J64_RS26850"
                     /old_locus_tag="SAMEA13201030_05342"
     CDS             5801..6457
                     /locus_tag="N4J64_RS26850"
                     /old_locus_tag="SAMEA13201030_05342"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879883.1"
                     /translation="MTEIKTECPDATWLRTTLAEMASDHFPVYDLPCLSVDPNSSAQLT
                     ALDDRRVAREMRQAAADVETRRIDAARVVEGLRTEAERLRGLIADGKTALRAGETVSPD
                     AGVAAFLLPDIEAELVAAEAAEADVARERDALLQDADRRDAAAAIGLFNLAHAVRVQRI
                     EQLLKLAMDEATLLAESDAGRSLYRTVINPDRRLNQLFSTQGAIEILRRNRGMEA"
                     /name="hypothetical protein"
     gene            6458..6841
                     /locus_tag="N4J64_RS26855"
                     /old_locus_tag="SAMEA13201030_05343"
     CDS             6458..6841
                     /locus_tag="N4J64_RS26855"
                     /old_locus_tag="SAMEA13201030_05343"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559064.1"
                     /translation="MSAFSMLCDRLRHEATLAKSTGAGDALAQVLETGGAAQTFAPIGA
                     PVASPTESVHRARAQSIQDAAFLTEMKQAGVAPADLVMLDGVLASSRGLPDASRAPAFA
                     AVRAQVQQQASLSPAARGINWDE"
                     /name="hypothetical protein"
     gene            6847..7203
                     /locus_tag="N4J64_RS26860"
     CDS             6847..7203
                     /locus_tag="N4J64_RS26860"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559062.1"
                     /translation="MPRHLQGKTRMPLAGGCYSAGHRLALISLLPVLEARPGDRDDGER
                     SKLALYQESLIKAGQPHAFALHEPSLYRWGAYLKSRRARYLQETDAGVAAASDALDRHA
                     FGRAIGAVLGADDE"
                     /name="hypothetical protein"
     gene            complement(7361..8002)
                     /locus_tag="N4J64_RS26865"
                     /old_locus_tag="SAMEA13201030_05344"
     CDS             complement(7361..8002)
                     /locus_tag="N4J64_RS26865"
                     /old_locus_tag="SAMEA13201030_05344"
                     /inference="COORDINATES: protein motif:HMM:NF016255.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_070559060.1"
                     /translation="MTETTRPILTIKRRNRTVYVPPEKAAKSEPQPAERTTSKAKVQPK
                     AKAPQKPAQKPTAAKPKKTPEQVAEGIRRQEENDRRQQDIAIANKSKKALANRVTKAFL
                     KEHWPDLLTRGVDRRPMAKGIIEQILTRGAELNMPPEADRKAVRRILGIVTGTSSYQQS
                     LIDQCMRYDLDGNPTEPATPEEAENAKARLTEIKAFRRKARQAKGEKKGA"
                     /name="ProQ/FINO family protein"
     gene            complement(7999..9288)
                     /locus_tag="N4J64_RS26870"
                     /old_locus_tag="SAMEA13201030_05345"
     CDS             complement(7999..9288)
                     /locus_tag="N4J64_RS26870"
                     /old_locus_tag="SAMEA13201030_05345"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_157698538.1"
                     /translation="MNDDNDTTEATQPSTEALKCVGAAERFPDIMPGVLFVTCPGGCSL
                     RVEACRQIYEQSHLDRTIENPHLECHRCPTGLALWVGTEQPPDAPLTTPADTRKLCPRC
                     SRKDNRLIAPNKPGSSLCVSCWNREREATIGANARGRVNRTPPFVSPFLIGIGDGWQVW
                     YGIHQGEALVRAMRANPGARFHDRRPGPVGQTRRDGFVYYCPEHREPLRWNGGDGHAGE
                     VELACPRCQPWAAPLSVAPTFQTVSFQTPHDAAHQYRNATLPDNAVWTSSVCADCKAAP
                     LVISKAPVKGKPRREIVVSCPSCDSSASARPGGRTWTDEHIAVPEFAQNETRSLAKIPV
                     ILPQGEQPQLLKRPGTGRGPGRPRKRIPLTLDRVPESRFNRLALSVLAAVGRWDYINDI
                     IRRIDRNRGDAATLIALADHIRTNRPERDL"
                     /name="hypothetical protein"
     gene            9644..9853
                     /locus_tag="N4J64_RS26875"
     CDS             9644..9853
                     /locus_tag="N4J64_RS26875"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765954.1"
                     /translation="MKKRIYTADLAALLNVSLRTLSRLSSRGIVPTPAGRSLRGGHYWL
                     AGDPVLKRFIADQRRPGRAPYGVR"
                     /name="hypothetical protein"
     gene            9840..11021
                     /locus_tag="N4J64_RS26880"
                     /old_locus_tag="SAMEA13201030_05346"
     CDS             9840..11021
                     /locus_tag="N4J64_RS26880"
                     /old_locus_tag="SAMEA13201030_05346"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765953.1"
                     /translation="MAFDNSHLTDAGLFWRAVSAAGAPVDREDWLRLCSGIACWASLCG
                     EDGLAAIEAWSTRHNRGSAHHRSQYRHFLKLKGVTNPEAMAQVFLRFSGEVYWRLDSNR
                     TPPSTEQVAALAERKRRSIEAVARREDADRRKADKAAADAVRMLAKGDGNPAYTPYWRN
                     KTTIARRGGVSLPPLPADLRVGGLFRSFEPRAYWSRCLLVPAYRLTDDRQLVGDALEAI
                     CGVCSAGGKTGDKFSPAGTQKAGRFYPMPGFMDVLDTSPHAPYSPLFVCEGFATAVALH
                     HLTKGKVAVCAAFSIAGFGSCVASLRRFWPDVDVMLVPDHGEAYRLAHKAAYGDEREPV
                     PTIPGAAVVSFDGLDRFTPRDNLDWFDVLVEEGEDRARELLRYAVRHARLERR"
                     /name="hypothetical protein"
     gene            11247..11705
                     /locus_tag="N4J64_RS26885"
                     /old_locus_tag="SAMEA13201030_05347"
     CDS             11247..11705
                     /locus_tag="N4J64_RS26885"
                     /old_locus_tag="SAMEA13201030_05347"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765952.1"
                     /translation="MKSKTELREAATARSLAVIATEMSEWSLDGFSHLKLPNFSAGERQ
                     QTLSGSVVVDRPPFDYEWAGTEKFNTLATRALQVKLPASRERNYAWLCGVERETLATAL
                     LVELFSVTGCVAFAGLGKVADLAFLTLDESEAGQIRAAMLQWLDGAAA"
                     /name="hypothetical protein"
     gene            complement(11960..12544)
                     /locus_tag="N4J64_RS26890"
                     /old_locus_tag="SAMEA13201030_05348"
     CDS             complement(11960..12544)
                     /locus_tag="N4J64_RS26890"
                     /old_locus_tag="SAMEA13201030_05348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004589499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351424.1"
                     /translation="MDITISDATYSRLAAQAKGFETPEQVINRLIDVVEIDHDTRPELF
                     FNPEGEADFKKALLKSKQAKVEMFKRDGSCETGVWNARAISEESSVRANIWSGYLRGWK
                     EKGIVRAVFTVQEVPDLPGAAESVQWNDYTISRTFSGGISVQRNGMPVTIVKPFLRDVA
                     HDLKISLLNSNGNEMNTRQLGAAIIKKLNNS"
                     /name="hypothetical protein"
ORIGIN
        1 aaaaccgccg atgctgctag atccgaaagg aaccaatgaa gggaaatatt taggcgttat
       61 ggttcattct cattaaattg aggagaattg cttaaatggg cgtccttcct atcaccctcg
      121 ctgtatagct ttacatttgg cctccgttgc atggtatgca gtcacggggg ccaaattatt
      181 ttcagagaca tcaactatcg ccattgcgaa aaagccagcc ccagcaacgt taatgcgacg
      241 aacagcattg agcacaatag tctgctccga gtaatctctg ttaacgtaca cattgctctg
      301 cactgagaat gcagttgcca aaatctccgc acactcttgc caacttagct tatccttcga
      361 gttacgagca gatagcacat gcctaaacat tgcccaagtg atcggtattg ctggtgatgc
      421 aggtatgtcc cagccgtttc tctgacaaac aactttcatt tgattgaact gcttcttagt
      481 catcagatag gtaaaacaag gcgtctccca aacttcctga gggagacctt tatcatccat
      541 ttcttcagct tgctgtgtaa aagcatagaa agcgtcacgg atagcatcat caccgatagc
      601 cacttctttt ccttgtaaaa tttttatgtt cgaattttat catatttagc tatgtcactt
      661 aggactgcta attcagtagc ccactttccc gcaacttatg gcgatagtcc cggacacggc
      721 tggtgttcca ctcctgtccc gtcgctgtcc ggtgccctgc tgcgttcagt gccgacgcga
      781 tggcgggcag agtcgcgttc tctgcggtca tgctgacaat gagctggtca gcctcatcac
      841 tgacggcctg gaagcgcgga tcggctcccc gggggactat ctgtcttgca ggttgttgtg
      901 cgctttgtgg tgctgtttgt tgtgcggttt gtcgtgcagg tttaccgccg acggacagcg
      961 ccctgacttc agccctcagc gcttcgatgg cagctaaaag tttggtgtcc atcccttccg
     1021 gcttcgtgcc aagtccggcg ttcagcgcct ctatgacagc atccgtgcgg gttgctccgg
     1081 ttcgtgctgc gttctgctcg atgcgttcga tcaggctaac gggtaggcga acggtcaggg
     1141 ttttggtttt ctctctcatg gctgctgctc tccacgtcgt gcgttttgtc gtgctgtttg
     1201 tcttgcgtag tgtaatgcgt tttgtcgtgc gcgtcgaatt cgacgtcgtg cagttgtcgt
     1261 gcacagaggg gcgacggctt tgcgtcgccg gggtgccgtt tgtgtacatg gataaatagc
     1321 agaggcggcg cagagattga gctgggcgtg atcacgacag cgcgataagt gcgcggcgct
     1381 aagtggcgtg gagggttggg atcgggtaag ctgatctggc gtctgcggat ccggttgggg
     1441 atcttcgggc acaaaaaaag gcgacctgtt gggtggtcac ctttttctgc cgggggagct
     1501 ggtaactcct ccgattaatt cgagtcacgt cttagcggga cgttctcgaa ggaagaatag
     1561 cacttgcgca gcgtactcct caaactcaaa gagaagtgta ccacgtcgat aagatcgcgc
     1621 aagtgtgaat ttccctcgta agcccccgcc tgacgccgac tcctacgttt ttaaaggagt
     1681 aattgcgtgt cacaaattga tgaaaattcc ggcactgctg ccgacaacgt aacgccgatc
     1741 gccgctgcca aggtgggacg cccgtctcta caaaaaaaat acccgactac cgcgtttccc
     1801 gtggagctgg agatcaacta ccggaagggg cgctactcgt cctctcttga gaacgttgtc
     1861 gccgctatgc gctgccattc cgtcaccggc atccagctcg ctttcgatga gttctttgcg
     1921 gaggaggggg cgttcgtgaa cgggcaatgg tacccgctgt ccgacaacct agttaccgag
     1981 ctgcgtctgc gcctcgctgc tgccgacttc gagaaggtga ccaaggacaa tgcccgcgac
     2041 gccatgttct acgtctgcga tgagaacaaa ttcgacagcg cccagcgttg gctgacggct
     2101 caggaatggg acggcaaacc tcgcgtcagt tacttcttcg agcggtgctt caaatgccaa
     2161 ggggatcccg agtacctggc ggcggtcagc ctctacacct ggacggcgct tgccgggcgc
     2221 gtaatgaatc ccggaatcaa ggccgacatg gttccgctgc tgtacgggcg acagggtgcc
     2281 cgcaaatcga cgggcgttcg ccttatgtcg ccattccctg actcctactc cagcttcaac
     2341 ctgaacgaca aggacgactc cctagtgcgc cgtatgcgtg ggtgcctgat tggcgagctg
     2401 gaggagctgc gcggcctcca cgggcgcgac tccgaatcgg tgaaagcgtt cttctccgct
     2461 gcccacgacg agtgggtgcc gaaatttaaa gagttcaagg tgcgaaaccc gcgccgcgtg
     2521 gtgttcatcg gtaccacgaa caacaagcag atcctcaatg actcgacggg gaaccgccgc
     2581 tatttgccca tgaattccgg ggacgtggac tgcgcggcca tcgagaaaaa ccgctcgcag
     2641 ctgtgggctg aagcgctcca cctgttcaat gagaatgggg tgatgtggga ggccgctgaa
     2701 acgctggcgc gtaaggtgca tgacgagttc cgcgtcgagg atccgtggga agacgagatc
     2761 gccgagctgc tcaagctgga cgttgacgac tgcgacccga ctgctttcgt gccgacgaag
     2821 gccttgttct ctcaggtagg gctcatgatt ggccatacca gcaacaagca gcatcagcgc
     2881 atggcggcta tcatgtcccg attgggctat gaggttggca ggaagcgcat aaacggtgcg
     2941 ttagttcgtg gctacttccg tcgaacgcaa gctgtcgtgt aagggttact tttccgtaag
     3001 aggggagcta tatgctcccc ttttttattg ttccacccgg gtggatcacg ggtggatcat
     3061 cacgccgttt ttgtaccacc tgttccaccc gggtgttcca cccgttccac ccgtgttccg
     3121 cccgtggatg gaacagctaa ggcctcgtgt ttaaaggctt tcattgttgt gttccacccg
     3181 ttccacccta ttttctaatt aaaaacaaaa aatgaataaa ttgggtaaat agggggtaaa
     3241 tgctcactaa ttgaacaatt agttgttttt tttactattt atgaatctat gccggatcgg
     3301 gtggaacggg tggatcatct tggaatcgac gcgccgcagc tgcaccctgc cggatgcact
     3361 ttgcttgtct tattagatcg gtggatgggt tcgtcgtgcc gggatggtcg gtggtagtgg
     3421 ttctgagggg gatcggaggt ttgggtggcg ctgagggcac gaggctttcg cctcgcgctg
     3481 ggtggtcgtc tgttggttct gcgtgagggc ttgccctcgc gcacgcgagc ggtaacaact
     3541 cgttaacgtg cggatccgcg tatttcgcgg gctcccgggt tttctgcggc ggtaaagcgg
     3601 cggtaaaagg cggttttccc gccgttttca gctctgttgg cgattcatgc cctcgcgcat
     3661 gatgtcggcc tcggtgcctg gcttgatctc gtagatgacg cgctcgcgtt cctgcgtctt
     3721 gagtagggat gtcataaggc cgctgatcgc tttgaccatg gtggcgtcct tctccagcat
     3781 ggcctgtagc gaagctgtgc ggagggcttg caggtcggtg gcgtggcgct gtagcagctc
     3841 aaactggcgc tgtacaaagt ggttttttag gcgtcggatc gctgcctgtg gggtggcctc
     3901 gacggctcgc tgtgcgcgtt cgcgcatctc ctcgatgctg aggacgttgc tgggtgcgtc
     3961 ggtgcgggct ttcgcccaat ctctgacggt gcggggtggg atccccatgg tgcgtgcgac
     4021 ggtggctgcg gttgcgccgt cctgctccag tagtctgagc gcctgggctt tctgctcggt
     4081 ggtgtatttc ttcatggtgt cctgctccgg ttggtttctc tcctgtattg aaacgtcacg
     4141 cgctgaaaat ggcgggggtt tttggggggt acacggcgtt tgtgcgtgcg tggtcgtgcg
     4201 gttgggtatt tttgtggctg aggcgcttag aatggctctg gtgcgttctg ggtaagggag
     4261 gaggcgcagc agtcgctgcg ctcctagctg gggttagcgc cagcgttcga ggcggtacct
     4321 gacggtgatc ccgtcctccg tcatggtatg gatgtactcc tggtttgcca cggtgcggtc
     4381 gatggccttg gtgcggtgct ttttgtacgt tttcatcctg gtttcttcgg agaagttctc
     4441 gccggtaacc atctcgtccc atgactcata tgactttgct ccgggaacca tgattacctt
     4501 ccatctctgg aacctacggg gaatgttttc aaatgccatc gttctctcct tatgattctg
     4561 gtttctgggg gcgctcccgc gcccctgtaa gtggttcgta atggcgtaag gcttttgtta
     4621 ttgcttgctg cttacacctg taaggctttc gttatggtca tgcttcccag gcgtaaaggc
     4681 tgatgatgct gactgtctgg taccgaccgg cgctgtcgcg gagggtggtc tggtactggc
     4741 ctttgcggtt ggcggcgcaa tggcggggct tgccgaactg gcggatctcg ccgtgttcaa
     4801 tgctcaggcc gggatagcgc ggtgttgctg cttggtttat catggttctg ttccttgttg
     4861 ggaatggtgc ccgggtctgc tcctcatgcg ttccccgggc tgggttgcgg cggtgtggaa
     4921 tggttggagc cacctacacc gctgcgctct ctcttactcc ggcgctaccg cgtcgacctt
     4981 ctcaaggtgg cggtaaatcg cgctcctgct cagatttaac tgcttggcta tggtggctat
     5041 tggtaccccc atggcgcggc gcatgactat ctcccccgct tctttcgcgc cgatcttggt
     5101 cgggcgtccg aacttctggc cacggctctt tgcggcctcg atccctgccg cctggcgttc
     5161 cagtatgagc ttgcgctcca tctgcgcgaa actcgccatg atgccgagga cggcctgtcc
     5221 gacggcgctg ctcaaatcga caccctcgcg gatgctgacc agggttactt ttcgtttctc
     5281 cagctcctcg accagttcga gggcgtcccg ggcgttcctg ccgatgcggt cgatcgcgta
     5341 gatgaccagc gtgtcgccct cctgcaggat ctggttcagg aggatgccga gggctggacg
     5401 ctcgcgtggt ggtaccgtcc cgctgatccc gtcgtcggcg aggatggagg ctgttgggaa
     5461 ccgggcgatg atggcgtcgc gctggctgtt gctggtttgt tcgtcggttg atacgcgaac
     5521 gtaaccgtat gttttgctca cttttttctc tcctctgacc gatacgtctc tttcgacaca
     5581 acatgccaca actgtaccga aagtctatcg ctaaagtgtc tatttcgtcg ctttgtcggg
     5641 tgtcccggaa tgtaggggat tagcgacggc ctccaggcgg ctctccgcgc tgggcgagag
     5701 ccctgcgccc tctgcgttga tgtctgcgcg gtgtcgtgac ggcatgctgt ctgagcggcg
     5761 tttgctgccg ctttgctgat aacttgctga gaaccaaacc atgaccgaaa tcaaaaccga
     5821 atgcccggac gcgacctggc tgcgtaccac gcttgctgaa atggcgagtg accattttcc
     5881 cgtttatgac cttccttgcc tgtcggtgga tcctaactcc tccgctcaac ttaccgcgct
     5941 tgacgatcgc cgggtggcgc gtgaaatgcg tcaggcagca gccgacgtgg aaacgcgacg
     6001 cattgacgcc gctcgcgtgg tggaagggct caggacggaa gctgaacgcc tgcgcgggct
     6061 gattgccgac ggcaagacgg cgctgcgtgc tggcgagact gtgagccccg atgcgggcgt
     6121 cgctgcgttc ctgctgccgg atatcgaggc cgagctggtt gccgccgagg ctgctgaggc
     6181 tgatgtggcc cgggagcgtg acgcgctgct gcaggatgct gaccgccgtg atgcggcggc
     6241 tgcgatcggc ctgttcaacc tggcgcacgc cgtgcgcgta cagcgtattg agcagctgct
     6301 gaagctggcg atggatgagg cgacgctgct tgccgagtcc gacgcggggc gcagtttgta
     6361 ccgtactgtt atcaatcctg atcgccgcct gaaccagctg ttctccacgc agggtgcgat
     6421 cgaaattctg cgccgcaatc gcggcatgga ggcgtaaatg tctgcatttt cgatgctgtg
     6481 tgaccggctt cgccatgagg cgacgctggc aaaatctacc ggggccggcg acgcgctggc
     6541 gcaggtgctg gagacgggcg gtgctgcgca gacgttcgcg ccgatcgggg ctccggttgc
     6601 ctctcctacg gagtcggttc accgggcgcg tgctcagtcc atccaggatg cggcgttcct
     6661 gactgagatg aaacaggcgg gcgtggctcc tgccgatctg gtgatgcttg acggcgtgct
     6721 ggcctcctct cgcggactcc ctgatgcgtc gcgtgctccg gcgttcgctg cggtgcgtgc
     6781 tcaggtgcag caacaggcgt ctctctcccc tgctgcccgg ggtatcaatt gggacgagta
     6841 aagccgatgc cgcgccacct gcagggtaag acgcggatgc cgctggcagg tggttgttac
     6901 tctgctggcc accgtcttgc gctgatctcg ttgctgcctg ttctggaggc tcgtcctggt
     6961 gacagggatg atggtgaacg atcgaagctg gcgctgtatc aggaatcgct gatcaaggcc
     7021 gggcaaccgc acgcgttcgc gttacatgag ccgtcgctgt atcgctgggg ggcgtatctg
     7081 aagagccgcc gcgcccggta tttacaggag acagacgcag gtgttgctgc ggcctcagac
     7141 gcgcttgatc ggcatgcttt cgggcgtgct attggtgcgg tcctgggggc tgatgatgag
     7201 tgagtttgcc gtctcgcgtc tggtcatccc tgaggtggtg atccctgacg gggttgttgc
     7261 tgcgcgaaag gccaggggga tcgcgcaacg tgtcgcagct gctcgccgtg ctgctgaacg
     7321 tcgtgctgcg cctacatggt gctgggtgag acggggcgcg ttatgcgccc tttttttcgc
     7381 ccttcgcctg gcgtgccttg cgccggaatg ccttgatctc tgtcaggcgg gctttggcgt
     7441 tttcggcctc ctccggggtt gctggttcgg tggggttgcc gtccaggtcg tagcgcatgc
     7501 actggtcgat gaggctctgc tggtacgagc tcgtacccgt gacaatgccc aggatgcgac
     7561 ggacggcttt gcggtctgcc tctggcggca tgttcagctc tgcgcctcgg gtcaggatct
     7621 gctcgatgat gccctttgcc atggggcgac ggtcaactcc ccgggtcagc aagtcaggcc
     7681 agtgctcttt caggaatgct ttggtcaccc ggttggccag cgcctttttg gacttgttgg
     7741 cgatcgcgat gtcctgctgg cggcggtcgt tctcctcctg tctgcggatc ccctcggcga
     7801 cctgttcagg cgtctttttc ggctttgccg ctgtgggctt ctgtgcgggc ttctgcgggg
     7861 ctttcgcttt tggctgtacc ttcgccttgc tggtagtccg ttcggctggc tgcggctcag
     7921 atttcgcggc cttttccggc gggacgtaga ccgtgcggtt gcgtcgcttg atggtcagga
     7981 tcggacgggt ggtttcggtc ataaatctct ctctggtcgg ttggtccgga tgtggtcggc
     8041 aagggcgatc agggtggcgg cgtcgccgcg gttccgatcg atgcgccgga tgatgtcgtt
     8101 gatgtagtcc cagcgcccga cggcggcaag gacggaaagg gcgaggcggt tgaaccggct
     8161 ctctggtacc cggtcgaggg tcagggggat gcgcttgcgg gggcgtcctg gaccgcgccc
     8221 tgtccctggt cttttgagca gctgcggctg ctccccctgc ggcaaaataa cggggatctt
     8281 cgccaggctg cgcgtctcgt tctgcgcgaa ctcgggcacc gcgatgtgct cgtctgtcca
     8341 tgtcctgcct ccgggcctgg ctgatgcgct ggagtcgcag gacgggcagg agacgacgat
     8401 ctcccgtcgc ggcttgccct tgaccggtgc cttgctgatc accaggggcg cggctttgca
     8461 atcagcgcag accgacgatg tccagaccgc gttgtctggc agggtggcgt tccggtactg
     8521 gtgcgcggcg tcatgcggtg tctggaagct gaccgtctga aacgtggggg cgacgctgag
     8581 aggtgccgcc catggctggc acctgggaca agcaagctcc acctctccgg cgtgcccgtc
     8641 gccaccgttc cagcgcaggg gctcgcggtg ttcggggcag tagtacacga aaccgtcgcg
     8701 gcgtgtttgc ccgaccgggc ctggtcggcg atcgtggaac cgtgcgcccg ggttggctcg
     8761 catggcgcgg acgagcgcct cgccctggtg gatgccgtac cagacctgcc agccatcgcc
     8821 gatgccgatc aggaacggcg agacgaacgg tggggtgcgg ttgactctcc cgcgtgcgtt
     8881 ggctccgatg gtggcttcgc gttcgcggtt ccagcaggag acgcacaggc tcgaaccggg
     8941 cttattgggg gcgatcaggc ggttgtcttt ccggctgcaa cgggggcaga gcttacgggt
     9001 gtctgccggg gtggtcagtg gtgcgtcagg gggctgttcg gtaccgaccc aaagcgcgag
     9061 gccagtgggg caccggtggc actcgaggtg ggggttttca atcgtgcgat cgaggtggct
     9121 ctgctcataa atctgtcggc atgcctcgac ccggagggag cacccgccgg ggcaggtgac
     9181 gaacaaaacg ccgggcatga tgtcggggaa ccgctccgca gcgcctacgc acttcagtgc
     9241 ctcggttgac ggctgcgtcg cttctgtcgt gtcgttatcg tcgttcactg ctccccctgc
     9301 gtcgaaatgg tcgccagacc tcgccagcac tggctgtgcg tcttttttag tatctcacaa
     9361 aaaacgccac tttggcgtta attgtgttaa gcttgtctta ctgattcctg acgagcagtt
     9421 gggaaacatg aaaccggatc gcccggtgcc gctttccctc ctccccaacg aggcggggtt
     9481 gtaaacgagg atgcgcgctt cgtccttggc aggtgcgagt aagcgagaag ggctgctgtc
     9541 ctgccgctat gcggtaagtc ctcaagggcg gctttatcga taatcgtcac tcccgccccc
     9601 cgatgcccgt taagctgagg ggggcaccta tctggtactc ccaatgaaaa aacgaatcta
     9661 taccgctgac ctcgctgcgc tgctgaacgt gtcgctgcgc acgctctccc gcctgagttc
     9721 gcgggggatc gttccgactc cggcagggcg ttcccttcgt ggcgggcatt actggctggc
     9781 tggggatccc gtgctcaaac gctttattgc cgaccagcgt cgtcccggga gggctcctta
     9841 tggcgttcga taactctcac ctgactgacg ctggcctgtt ctggcgtgcc gtctctgcgg
     9901 ctggggctcc ggttgaccgc gaggactggc tgcgcctctg ttctggcatc gcatgctggg
     9961 catctctctg cggagaggac gggcttgctg ctatcgaggc ctggtctacc cgccacaatc
    10021 gcggatctgc gcatcaccgg tcgcagtacc ggcacttcct gaagctgaaa ggcgtaacca
    10081 atcccgaggc catggcgcaa gtattcctgc ggttctcagg cgaggtgtac tggcggctcg
    10141 actcaaatcg cacgccgccg tcgactgaac aggttgctgc tcttgctgaa cggaaacgcc
    10201 gatcgatcga ggcggtggcc agacgcgaag atgccgaccg gcgcaaggcc gataaggctg
    10261 cggctgatgc ggtcaggatg ctggcgaaag gcgacggtaa tccggcctat accccgtact
    10321 ggcgcaataa gaccacaatc gccaggcgtg gtggcgtcag cctcccgccc ctccccgctg
    10381 accttcgtgt gggtggcttg ttccgctcgt tcgaaccgag ggcgtactgg tcgcgctgtc
    10441 tgcttgttcc tgcctatcgc ctgaccgatg atcgccagct ggttggcgac gcgctggagg
    10501 ccatctgcgg cgtctgctct gctggcggca aaaccggcga caagttctcc cctgcaggta
    10561 cccaaaaggc gggacggttc tatccgatgc ccggctttat ggacgtgctc gatacctcac
    10621 cacatgcgcc ctactcgcct ctgttcgtct gtgaggggtt cgccacggcg gttgccctgc
    10681 atcatctgac gaagggcaag gtggcagtct gcgcggcgtt ctcaattgcc gggttcggca
    10741 gctgcgtggc gtcgctgcgc cggttctggc cagatgttga tgtgatgctg gtaccggatc
    10801 acggcgaagc gtaccgcctg gcgcataaag cggcctatgg cgatgagcga gagccggtcc
    10861 cgacaattcc aggcgcggcg gttgtgtcgt tcgacggcct cgatcgcttc acgccccggg
    10921 ataacctcga ctggttcgac gtgctggttg aggaagggga agatcgggct cgtgagctgc
    10981 tgcgctacgc ggttcgtcat gcccggcttg agcggcgttg attggcgtgt ccgaatggtg
    11041 cgcctttcgg gacatctttt ttgccgtcgt ggcgtctggt ttagcgaacg actttcgaga
    11101 cactaccgat gcttttttga tgagacggac taaagcgacg caccggcgct gccgtcgtga
    11161 cgctatcctg cgatcggttt ctcacagcag cataaagccc ggcctcgtct tgatgtcggg
    11221 ttttttttta gcccaaagga gggcacatga aatcaaagac tgaactacgc gaggccgcga
    11281 cggctcgctc tctggcggtg atcgccactg aaatgtcgga gtggtcgctc gatgggttct
    11341 cccacctcaa gctgccgaac ttctccgctg gggaacgcca gcagacgctg tccgggtcgg
    11401 tggtggttga tcgcccgccg ttcgactacg agtgggctgg taccgagaaa tttaacactc
    11461 tggccacccg tgcgctgcag gtgaaacttc cggcatcgcg tgagcgtaac tacgcctggt
    11521 tgtgcggcgt tgaacgggag acgctggcga cggcgctcct cgtggagctg ttctccgtca
    11581 ccggctgcgt ggcgttcgcc gggctgggta aggttgccga tctggcgttc ctgacgctgg
    11641 acgagagcga ggcggggcag atcagggcgg cgatgctgca gtggctcgat ggggcggcgg
    11701 cgtaggggct cgatcctcga tcagctggag tgggaagggc gactgatcga ggaggccatg
    11761 gcgacggaac tgcggggcga cccggtgcgc tgcgaccacc ttgctgcggc gcggttatgg
    11821 ctggagtgtg ttgaccgggc gtctgatgac aggtggcggg cgttctgcct cgccagctat
    11881 gaatggtgcg tattcgtcgc agtagaactc tgaccggcgg cggcgttgag ccgtcgctcc
    11941 tctgcgtgaa gcatcgatgt taagagttat ttaacttctt tatgatcgct gcgccaagct
    12001 gccgagtatt catttcattt ccattgctat ttagcaatga tatttttaaa tcatgcgcaa
    12061 catcacgtag aaatggcttc acaatagtta caggcatgcc atttctttga actgaaatac
    12121 cgccactaaa agtgcgactg attgtataat cattccactg cacactttca gccgctcctg
    12181 gcaagtcagg aacctcctgg acagtgaaaa ccgcacgaac aatccctttt tccttccatc
    12241 cacgcaaata cccactccaa atatttgccc gaactgatga ttcttctgaa atcgcacgag
    12301 cattccatac tccagtttca caggaaccat cccttttaaa catttcgact ttggcctgtt
    12361 ttgattttag taacgctttt ttaaaatccg cttcaccttc aggattaaaa aaaagttcag
    12421 ggcgtgtgtc atgatcgatt tcaacaacat cgatcagacg gtttattacc tgttcgggag
    12481 tttcaaatcc ctttgcttgt gcagcaagac ggctatatgt agcgtcagat atcgtaatat
    12541 ccatcaaagt acctctatag atcaaaaatt aatcataaaa ttaatcataa ttgataaatt
    12601 taatgatttc aagatctata attacctgat atcgcaatat ggttaaccgc ctctaaagag
    12661 ctataaaaac ctgtaaaccc gctcctcgtg ccgcttggtt ataaacaaac cagttgaatc
    12721 tacgtcaaca atagcctact attgttgtac tgcaagagca ttcgcagggg gtattaacca
    12781 gtaattaacc ctttgcgctg ggcagtcagg aggctggtct cctgttggga agttatgttg
    12841 cggcttccta gtaataacag tgaatttga
//
