LOCUS       NZ_OW970497             7926 bp    DNA     circular CON 20-JUN-2024
DEFINITION  Klebsiella pneumoniae isolate 147 plasmid P5, complete sequence.
ACCESSION   NZ_OW970497
VERSION     NZ_OW970497.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA7082332
            Assembly: GCF_903993145.2
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Alioto,T., Alioto,T. and Gomez Garrido,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-MAY-2022) CNAG-CRG, CNAG, Spain
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_903993145.2-RS_2024_06_20
            Annotation Date                   :: 06/20/2024 03:56:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,547
            CDSs (total)                      :: 5,426
            Genes (coding)                    :: 5,289
            CDSs (with protein)               :: 5,289
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 49 of 137
            Pseudo Genes (incomplete)         :: 87 of 137
            Pseudo Genes (internal stop)      :: 17 of 137
            Pseudo Genes (multiple problems)  :: 14 of 137
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OW970497.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7926
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /isolate="147"
                     /isolation_source="Hospital Univeristario de Bellvitge
                     (Barcelona)"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="P5"
                     /geo_loc_name="Spain"
                     /collection_date="2017"
     gene            complement(join(7869..7926,1..548))
                     /locus_tag="LQV37_RS27525"
     CDS             complement(join(7869..7926,1..548))
                     /locus_tag="LQV37_RS27525"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509965.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGCAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            643..3540
                     /locus_tag="LQV37_RS27530"
                     /old_locus_tag="AI2996V1_5227"
     CDS             643..3540
                     /locus_tag="LQV37_RS27530"
                     /old_locus_tag="AI2996V1_5227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="WP_001553819.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            4546..5052
                     /locus_tag="LQV37_RS27535"
                     /old_locus_tag="AI2996V1_5228"
     CDS             4546..5052
                     /locus_tag="LQV37_RS27535"
                     /old_locus_tag="AI2996V1_5228"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_142304992.1"
                     /translation="MEIEFENIGFIKSGKIKTNNITVIFGPNNVGKTYLSYSTYAAISR
                     YNDIFREKIKIPKSVSSNLVLNGTARYDITNVFTDSLVKSVNEEVSSSLPAFFKDSSGM
                     FSKSKISVIDSYIKDRVVNSEVNVNISVSENIILNIQKKKTIHVLILQLPHPKRIMSQG
                     VLSLI"
                     /name="hypothetical protein"
     gene            4989..5969
                     /locus_tag="LQV37_RS27540"
                     /old_locus_tag="AI2996V1_5229"
     CDS             4989..5969
                     /locus_tag="LQV37_RS27540"
                     /old_locus_tag="AI2996V1_5229"
                     /inference="COORDINATES: protein motif:HMM:NF024573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_229976729.1"
                     /translation="MDFTVTSSKKNNESGSPVIDLKEKDASNYLNILFNFFFLNEVLDS
                     AANNAFIITSERTGISLFQKEIDGNRSNIVDSYMWSKLSTRKLLSFDDIMSQKVAKFSE
                     PINHNINIIRDFADLKKMKHIMTANGVRRASKERTDVIKTLESLTGGRYSTSDGEAIFT
                     VSCSDGDKVSMPLSLSSASNKALFLLDIYVRYYMSNNSYLIIDEPELNLHPHNQIKMAE
                     LLVRLSNCGVKIIITTHSDYIVKEINNRIMASQLKDKSRLTELGYKEADLIFSSEVNGF
                     TIGNDGAISEVEGNRYGVNAFLFDNVINDIENKADLLYTYLEEGL"
                     /name="AAA family ATPase"
     gene            5971..6603
                     /locus_tag="LQV37_RS27545"
                     /old_locus_tag="AI2996V1_5230"
     CDS             5971..6603
                     /locus_tag="LQV37_RS27545"
                     /old_locus_tag="AI2996V1_5230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011977833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_029364653.1"
                     /translation="MLERFIDVLNKDVLFDLSATPSPDSSVLVVREDGELSEIKELTIK
                     EIPDDSIAFTLDFSSKKNSKENGALFSQLSPYFDKSNGDGVNKSCDLVLITRDGDKFTV
                     LIFDQKSKKPDIESSFLQLENSRVFVSYVINIISLIYKDNIDEGKIVFKRVIGTTRVVK
                     TGVNAANHEQERSRREKLRALGMNEVSIKRTASIEKGWLDYRGIVSF"
                     /name="hypothetical protein"
     gene            7349..7540
                     /locus_tag="LQV37_RS27550"
                     /old_locus_tag="AI2996V1_5231"
     CDS             7349..7540
                     /locus_tag="LQV37_RS27550"
                     /old_locus_tag="AI2996V1_5231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_004187666.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            7540..7872
                     /locus_tag="LQV37_RS27555"
                     /old_locus_tag="AI2996V1_5232"
     CDS             7540..7872
                     /locus_tag="LQV37_RS27555"
                     /old_locus_tag="AI2996V1_5232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_227641188.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCSGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSGQVSEQRDTASADQSEQVIRHLKQEIEHLNTLLLSKEGSVPA
                     EGEMTP"
                     /name="helix-turn-helix domain-containing protein"
     Typing          complement(6825..7226)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.611"
                     /coverage="99.0"
                     /evalue="3.5900000000000006e-163"
ORIGIN
        1 agctcgcgtg cgatccagcg atagctgcgt ccctcggccc tcatcgcaac caccttaggc
       61 aaaagtcggt ctgattttgg tcgcactccg gcctgacgac caagcctctt accacgtgcc
      121 ttcgcaacag caaggcctga cttgacccgc tcgctgatga gatcccgctc aaactccgca
      181 atgccggaaa gaaacgtcgc cagcattcgt ccatacggcg acgaaagatc gaacgccatt
      241 ccattcatgg ctatcacgga aaccttccag ttctccagtt cacgtagcgt attgagcaga
      301 tcgagcgtcg agcgccccca ccgggaaagc tcagtgacca ggattgcatc aatttgtctg
      361 gactgggcaa gcgccaggac tttctttcgc tcggcccggt cgagtttagt tcctgaacct
      421 gtttccttaa atattcccac cacgtcgtag ccggcacagc cggcgaaggc tcgcagatca
      481 aattcctggc gttcacaaga ctgatccgct gttgaaaccc ggcagtaaat ggcggcacga
      541 tgtcccaatt gaaccctcct ggatttttgt atcggaacgc cctgatttat atgggctggc
      601 tgttgtccaa aacagactat acttcaaaag ggacgaattt gtatgtcacg acgccatatt
      661 ttcaccgaac ggcagcgagc agcgctgttc gatctgccca cggacgaact gtcgctactg
      721 aagttctaca cgctgggcga tgatgacctg gaaaacatta ggcagcgccg cagaccggaa
      781 aacaggattg gctttgccct gcaactttgt gccttacgat atccgggccg tgcactggct
      841 cctggtgaga tgatcccgcg tgaagtcctt tccttcgtcg gtgctcagct tggagttccg
      901 gctgatgcgc ttctcactta tgccacacgg cgccaaaccc gtcagcagca catggacacg
      961 ctgcgcgaaa tttacggcta caagaccttc acgggccgtg gtgcccgtga tctgcgggag
     1021 tggactttcg gccaggccga agatgccaga tcaaacgagg atcttgctca tcgttttatt
     1081 gtgcggtgtc gggaaacttc caccattctg cccgcagtat cgacaatcga gcgcttgtgc
     1141 gcggatgctc tggtcgccgc tgagcggcgg attgaaacgc ggattgcgga aaatttaaca
     1201 gcggatgttc gcgatcacct ggacaaactt ctgagtgaaa tgctcgccgg caatatcagt
     1261 cgtttcatct ggcttcgcaa cttcgaggtt ggtaacaact cggctgctgc taaccgtttg
     1321 ctcgacaggc tcgaatttct gcgtaccctg aatatcaatc atagtgcttt ggccagcata
     1381 cctgcccatc gcattgcccg gctgcgtcgg cagggtgaac gctacttcac cgacggtttg
     1441 cgtgacatca cttcggaccg ccgctgggcg atccttgccg tctgtgttgt ggagtgggaa
     1501 gcggcgattg ctgatgccat agtcgaaacc catgacagga tcgtaggaaa aacctggcgg
     1561 gaagcgaagc gccagcatga cgaaacaatt tccggctcta aagccacact cacggatacg
     1621 atccgtacct tcaccgcgct gggagcttcg ttgcttgagg cccgcagtga cggaaccccg
     1681 ctggagatgg ctgtcgccag ttcggttgca tgggaccggc tcgctcaact ggtagcgaca
     1741 gggactcaac tcagcaacac gctagccgat gagcctcttg catatgtcgg gcagggatac
     1801 catcgctttc gtcgttatgc gccccgcatg ttgcgctgtc tgaagctcga agccgcgccg
     1861 gtcgccggac cattggtagc agcagctttg tcgatcggag agatgaaagg tgttgcatcg
     1921 ccagaaaggc gtttcctgcg gcccagctcc aaatggaacc gtcatttacg agctcaggaa
     1981 aaaggagata cccgtctttg ggaagtggcg gtactctttc acctccggga tgcttttcgt
     2041 tccggagatg tctggctcgc tcattcgcgc cgctatggtg acctcaagca ggtactggtg
     2101 ccgatgatcg cggcgcagga aaatgcaaaa ctggccgtgc cttccaaccc acaggattgg
     2161 ctggcagaca gaaaggcgcg actcacgatc gctcttaagc ggctggcccg ggctgcccgt
     2221 aacggcacta ttccgcacgg tagcatagaa gatggaacgt tgcggatcga caggttgaca
     2281 gcagacgtgc cggatggtgc cgaggcactc atactggatc tgtatcgccg aatgccgtcc
     2341 gttcggatta ccgacatgct gcttgaagtt gatgcagccc ttggtttcac agatgcgttt
     2401 acccatctga gaaccggggc tccatgtcgc gaccggatcg gtctgctcaa cgtcctgctc
     2461 gctgaagggc tcaatctggg cctgcgtaag atggcggaag ctacaaacac gcatgattac
     2521 tggcagctct cacgccttgc ccgctggcat gttgaaagcg aagccatgaa ccaggcattg
     2581 gcaattgtgg tggccgcgca gggtaaactg ccgatgtcac gcgtctgggg gatgggcacg
     2641 tcagcatcga gcgatggtca gtttttcccg acagcgcggc atggcgaagc catgaacatg
     2701 gtcaatgcca aatatggttc tgttcccggc ctcaaagcgt atactcacgt aagcgaccag
     2761 ttcgcgccat tcgcttgtca gtcgatcccg gcgaccgtga gcgaggcacc gtatattctc
     2821 gatggactac tgatgaacga ggtcggtcgc catgttcgcg aacagtatgc cgatacagca
     2881 ggattcaccg accatttgtt cggagccagt agcctgctcg gctacaatct cgttctgcga
     2941 atcagggatc tgccatcgaa gcggttgtac gtatttaatc ccgatacgac ccccagggag
     3001 ttacgcaagt tggtaggtgg aaaagcccgg gaggatctta tcgttgcgaa ctggcctgat
     3061 attttccgtt gtgccgcgac gatgaccgct ggcaaaatca ggcccagcca actcctgcgc
     3121 aagctcgctt cttacccacg acaaaacaac cttgcagttg cgcttcgtga agttggtcgt
     3181 attgaacgga cccttttcat tattgagtgg atcctggata cggacatgca gcggcgtgct
     3241 cagatcggtc ttaacaaggg agaggcccac catgcgctca aaaatgcgct ccgtatcggg
     3301 aggcaggggg aaattcgcga tcgcacgaca gaggggcagc actaccgaat cgctgggctc
     3361 aatttattga ctgcggtgat catttactgg aataccgtcc atcttggtca tgccgtcacg
     3421 gagcggcgga acgaagggtt ggatgttccc cctgaatttc ttccccacat atccccattg
     3481 ggctgggcgc acattctact gactggcgaa tatctttggc ccaaggaacc gaaagcttag
     3541 ggtgtcattt cgccctcagc cggaaccgac cccaaggatt cgcacattga cagcctgaaa
     3601 caggccatgc tccttcttga aaatcaccag gcaaaattaa ctgaatcccc ggcgccatgg
     3661 tggaaattct ggaaaaaatc ctgatcctgc catgcttgag ttttcctctc cggccatccc
     3721 ggggagttcc tgaaccttcc caaaatcgcc agatctctga acgctcctca ccactaaaaa
     3781 tatccacaca ctacgcaaaa ttaaaatttt gcggatttgt atttaatatc agttagttac
     3841 tttcctgaaa tttcgttttt taaattttat ttacatagat ccgactctat gacgactcgt
     3901 catagagtcc ccggcgagtc gtcatggagt cggtaacgac tcaggactat aaaaacaatg
     3961 agttaataac gacccgactc tagacccgac tccccgtttg gttgtttttt agacgtggcg
     4021 actctgggta cgactctagt gaagagtcgc cggtgaatcg tgtggtgagt cgtccggcga
     4081 cttgccacac gattcaccgg ctgtcgatgg gcccgattcc tgaaggtgtt gaaaacggtt
     4141 tttccggctg tgccggcaac gcctcacggc cacgcaataa attgcgtccc cattcaccgt
     4201 tttcagtcgg gtttggtgcg ggtttcgagt cgtctggcct aaattcaggc tgaaatctgc
     4261 caccagtcag tctggtgcat aacgattcat gcccgtaaaa cgccctggag cgattttgag
     4321 gcgttttcag ggggtaagac gtaggattta atgggttacg ccccagaatc gttctgaggc
     4381 cgttttagcg gtgcgtgtaa tgacgcgtta tggtaaatcc agtagttttt tgctcattca
     4441 ggagtggttt ttaaatcatc atgtatgaat atcttgtaat ggtaggtata gttagcatgg
     4501 atattgctaa ggataaaagc ataacatact tagtgggtga tgcgaatgga aatagagttt
     4561 gaaaatatcg gctttataaa aagcgggaaa ataaaaacca ataacattac tgttattttt
     4621 gggccaaata atgtgggtaa aacataccta agttatagca catacgctgc tattagtagg
     4681 tacaatgaca tatttagaga gaaaataaaa ataccaaaat cagtatctag caacctggtt
     4741 ttaaacggaa ctgccaggta cgacatcaca aacgttttta ctgattctct tgttaaatca
     4801 gttaatgaag aggtttcatc aagcttgcct gcattcttca aagatagttc aggtatgttt
     4861 tctaaatcaa aaattagtgt gattgactct tatattaaag atagagttgt taattctgaa
     4921 gttaatgtaa atatttctgt cagtgaaaat ataatattaa atatacaaaa gaaaaaaaca
     4981 atacatgtat tgattttaca gttacctcat ccaaaaagaa taatgagtca gggagtcctg
     5041 tcattgatct gaaggaaaaa gacgcttcaa attatttaaa tattttattt aatttctttt
     5101 tccttaatga ggttttagac tctgcagcta ataacgcatt tataataaca tctgagcgta
     5161 ctggaatatc cttgtttcaa aaggagattg atggtaatcg tagtaatatt gttgattctt
     5221 acatgtggag taagttgtct acgaggaagt tactgtcttt tgatgacatt atgagccaga
     5281 aagttgctaa gttctcggag ccaattaatc acaatataaa tataataaga gactttgctg
     5341 atctgaaaaa aatgaagcat ataatgacgg caaatggtgt tagaagggca tctaaggagc
     5401 gaactgatgt tataaaaaca ctagagtcac ttactggtgg tagatactca acatctgacg
     5461 gtgaggctat ttttacagtt tcttgcagtg atggagataa agtgtcaatg ccactttctc
     5521 tctcatcagc atctaacaaa gcactatttc tattagatat atatgtaaga tactacatgt
     5581 ctaataactc ttacttgata attgatgagc cagagctgaa tctgcatcca cataatcaaa
     5641 ttaaaatggc agagttgctt gtaagacttt caaattgcgg agttaaaatt ataatcacaa
     5701 cgcatagtga ttatatcgtt aaagagatta ataatagaat aatggcttcg cagctgaaag
     5761 ataaatcacg attaactgaa cttggataca aagaagcaga tttgattttt tcgtcagagg
     5821 ttaatggttt tactatcggt aatgatggtg ccatctctga ggttgaaggg aataggtatg
     5881 gggtgaatgc ttttcttttt gataatgtta ttaatgatat agaaaacaag gctgatctct
     5941 tgtatacata tttagaagag gggctctaat atgctggaga ggtttattga tgttttaaat
     6001 aaagatgttt tgtttgattt gtcggcaact ccatctcctg actcttcggt gttagttgtt
     6061 cgtgaagatg gtgagcttag tgaaataaaa gagttaacta taaaagaaat acctgatgat
     6121 tcgattgctt tcactttgga tttttcaagc aagaaaaact ctaaagaaaa tggcgcttta
     6181 ttttctcaat tgtcgccata ctttgacaag tctaatggcg atggggtgaa taaatcttgt
     6241 gatcttgtat tgattacaag agatggcgat aagttcactg ttcttatttt tgaccaaaag
     6301 tcaaaaaaac ctgatataga atcatcattt ttgcagttgg aaaactcaag agtttttgtt
     6361 tcctatgtaa ttaatattat ttctttaatt tataaagaca atattgatga ggggaagatt
     6421 gtttttaaac gagttattgg gactacaagg gttgtaaaaa ctggagttaa tgctgctaat
     6481 catgagcagg aacgatcgag aagagagaag cttcgtgctc ttggcatgaa tgaagtctcg
     6541 ataaagcgta cggcatcaat agaaaaggga tggttggact atcgaggaat cgtttccttt
     6601 tagtctactt ccagtagtct caagtgcttg tgttgagaga ggaagaacgg tatctttcaa
     6661 catataaaga aaaaccaccg ctaccaacgg tggttttctt aaggtttatg gagctaccaa
     6721 ctcattaaac ctaggtagct ggcttggagg agcacagtca ccaaaacttg ttctttcagt
     6781 ttagccttaa caggcgtcta acttcaagac tatctcctct aaatcagtta ccagtggctg
     6841 ctgccagtgg cgcttttgca tgtcttaccg ggttggactc aagacgatag ttaccggata
     6901 aggcgcagcg gtcggactga acggggggtt cgtgcataca gtccagcttg gagcgaactg
     6961 ccttcccgga accgagtgtc aggcgtggaa tgagaaaccg cggccataac agcggaatga
     7021 caccggtaaa ccgaatggca ggaacaggag agcgcacgag ggagccacct atcagaaatg
     7081 ataggtatct ttatagtcct gtcgggtttc gccaccactg atttgagcgt ctttctgtga
     7141 tgcttgtcag gggggcggag cctatggaaa aacgacggcc gtgcggcctt tccttcttcc
     7201 cgtcatgcgg ctgctcggtt ttctcggcgt ttctacgcat gctcctgccg ctcgccgcag
     7261 ccgaacggca ggagcgtagc gactgagtga gcgaggaagc ggaaaagaga acatccttac
     7321 actgagcact gacgctctga ggcctcttat gacgaaacaa cagaaaacag cgctgaacat
     7381 ggctaaattc atccagaatc agtctctgct cctgctggag aagcttaacg agcttgatct
     7441 cgatgtcgag gccgaccttt gtgagaaact ccacgatgat gcggagcatc ttttccgtac
     7501 actgtcctcg agactggatg cattacagga tggtaactga tggccagagt gtctattagt
     7561 gaggctgccc gactgacggg taagagtaga acaacactgc acaggttaat taaagcaggt
     7621 gacctgtcca cctgtagcgg tgaacgcaat gcaaaaatgg tagatacttc agagctttta
     7681 cgtgtctttg gtccctttga gcaaccgaag ggtgaacacc attctggaca ggtctctgaa
     7741 cagcgtgata cagcctctgc tgaccagagt gaacaggtga ttcgtcatct gaaacaggag
     7801 attgaacacc tgaacacctt acttttgtcc aaggaggggt cggttccggc tgagggcgaa
     7861 atgacaccct aagcgttagc tctgtgtcgt tgcacgatgt cagcgacggt attcttgctg
     7921 ataccg
//
