LOCUS       NZ_OW970426             7926 bp    DNA     circular CON 20-JUN-2024
DEFINITION  Klebsiella pneumoniae isolate 147 plasmid P4, complete sequence.
ACCESSION   NZ_OW970426
VERSION     NZ_OW970426.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA7082330
            Assembly: GCF_903993095.2
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Alioto,T., Alioto,T. and Gomez Garrido,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-MAY-2022) CNAG-CRG, CNAG, Spain
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_903993095.2-RS_2024_06_20
            Annotation Date                   :: 06/20/2024 04:01:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,492
            CDSs (total)                      :: 5,371
            Genes (coding)                    :: 5,257
            CDSs (with protein)               :: 5,257
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 46 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 15 of 114
            Pseudo Genes (multiple problems)  :: 11 of 114
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OW970426.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7926
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /isolate="147"
                     /isolation_source="Hospital Univeristario de Bellvitge
                     (Barcelona)"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="P4"
                     /geo_loc_name="Spain"
                     /collection_date="2017"
     gene            complement(join(7904..7926,1..310))
                     /locus_tag="LQV34_RS27275"
     CDS             complement(join(7904..7926,1..310))
                     /locus_tag="LQV34_RS27275"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_227641188.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCSGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSGQVSEQRDTASADQSEQVIRHLKQEIEHLNTLLLSKEGSVPA
                     EGEMTP"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(310..501)
                     /locus_tag="LQV34_RS27280"
                     /old_locus_tag="AI2770V1_5182"
     CDS             complement(310..501)
                     /locus_tag="LQV34_RS27280"
                     /old_locus_tag="AI2770V1_5182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000166328.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDAEADLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(1247..1879)
                     /locus_tag="LQV34_RS27285"
                     /old_locus_tag="AI2770V1_5183"
     CDS             complement(1247..1879)
                     /locus_tag="LQV34_RS27285"
                     /old_locus_tag="AI2770V1_5183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011977833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_029364653.1"
                     /translation="MLERFIDVLNKDVLFDLSATPSPDSSVLVVREDGELSEIKELTIK
                     EIPDDSIAFTLDFSSKKNSKENGALFSQLSPYFDKSNGDGVNKSCDLVLITRDGDKFTV
                     LIFDQKSKKPDIESSFLQLENSRVFVSYVINIISLIYKDNIDEGKIVFKRVIGTTRVVK
                     TGVNAANHEQERSRREKLRALGMNEVSIKRTASIEKGWLDYRGIVSF"
                     /name="hypothetical protein"
     gene            complement(1881..2894)
                     /locus_tag="LQV34_RS27290"
                     /old_locus_tag="AI2770V1_5184"
     CDS             complement(1881..2894)
                     /locus_tag="LQV34_RS27290"
                     /old_locus_tag="AI2770V1_5184"
                     /inference="COORDINATES: protein motif:HMM:NF024573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_336297447.1"
                     /translation="MKYTKEKNNTCIDFTVTSSKKNNESGSPVIDLKEKDASNYLNILF
                     NFFFLNEVLDSAANNAFIITSERTGISLFQKEIDGNRSNIVDSYMWSKLSTRKLLSFDD
                     IMSQKVAKFSEPINHNINIIRDFADLKKMKHIMTANGVRRASKERTDVIKTLESLTGGR
                     YSTSDGEAIFTVSCSDGDKVSMPLSLSSASNKALFLLDIYVRYYMSNNSYLIIDEPELN
                     LHPHNQIKMAELLVRLSNCGVKIIITTHSDYIVKEINNRIMASQLKDKSRLTELGYKEA
                     DLIFSSEVNGFTIGNDGAISEVEGNRYGVNAFLFDNVINDIENKADLLYTYLEEGL"
                     /name="AAA family ATPase"
     gene            complement(2798..3304)
                     /locus_tag="LQV34_RS27295"
                     /old_locus_tag="AI2770V1_5185"
     CDS             complement(2798..3304)
                     /locus_tag="LQV34_RS27295"
                     /old_locus_tag="AI2770V1_5185"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_142304992.1"
                     /translation="MEIEFENIGFIKSGKIKTNNITVIFGPNNVGKTYLSYSTYAAISR
                     YNDIFREKIKIPKSVSSNLVLNGTARYDITNVFTDSLVKSVNEEVSSSLPAFFKDSSGM
                     FSKSKISVIDSYIKDRVVNSEVNVNISVSENIILNIQKKKTIHVLILQLPHPKRIMSQG
                     VLSLI"
                     /name="hypothetical protein"
     gene            complement(4310..7207)
                     /locus_tag="LQV34_RS27300"
                     /old_locus_tag="AI2770V1_5186"
     CDS             complement(4310..7207)
                     /locus_tag="LQV34_RS27300"
                     /old_locus_tag="AI2770V1_5186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="WP_001553819.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            7302..7907
                     /locus_tag="LQV34_RS27305"
                     /old_locus_tag="AI2770V1_5187"
     CDS             7302..7907
                     /locus_tag="LQV34_RS27305"
                     /old_locus_tag="AI2770V1_5187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509965.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGCAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     Typing          625..1026
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.611"
                     /coverage="99.0"
                     /evalue="3.5900000000000006e-163"
ORIGIN
        1 ccggaaccga cccctccttg gacaaaagta aggtgttcag gtgttcaatc tcctgtttca
       61 gatgacgaat cacctgttca ctctggtcag cagaggctgt atcacgctgt tcagagacct
      121 gtccagaatg gtgttcaccc ttcggttgct caaagggacc aaagacacgt aaaagctctg
      181 aagtatctac catttttgca ttgcgttcac cgctacaggt ggacaggtca cctgctttaa
      241 ttaacctgtg cagtgttgtt ctactcttac ccgtcagtcg ggcagcctca ctaatagaca
      301 ctctggccat cagttaccat cctgtaatgc atccagtctc gaggacagtg tacggaaaag
      361 atgctccgca tcatcgtgga gtttctcaca aaggtcggcc tcagcatcaa gatcaagctc
      421 gttaagcttc tccagcagga gcagagactg attctggatg aatttagcca tgttcagcgc
      481 tgttttctgt tgtttcgtca taagaggcct cagagcgtca gtgctcagtg taaggatgtt
      541 ctcttttccg cttcctcgct cactcagtcg ctacgctcct gccgttcggc tgcggcgagc
      601 ggcaggagca tgcgtagaaa cgccgagaaa accgagcagc cgcatgacgg gaagaaggaa
      661 aggccgcacg gccgtcgttt ttccataggc tccgcccccc tgacaagcat cacagaaaga
      721 cgctcaaatc agtggtggcg aaacccgaca ggactataaa gatacctatc atttctgata
      781 ggtggctccc tcgtgcgctc tcctgttcct gccattcggt ttaccggtgt cattccgctg
      841 ttatggccgc ggtttctcat tccacgcctg acactcggtt ccgggaaggc agttcgctcc
      901 aagctggact gtatgcacga accccccgtt cagtccgacc gctgcgcctt atccggtaac
      961 tatcgtcttg agtccaaccc ggtaagacat gcaaaagcgc cactggcagc agccactggt
     1021 aactgattta gaggagatag tcttgaagtt agacgcctgt taaggctaaa ctgaaagaac
     1081 aagttttggt gactgtgctc ctccaagcca gctacctagg tttaatgagt tggtagctcc
     1141 ataaacctta agaaaaccac cgttggtagc ggtggttttt ctttatatgt tgaaagatac
     1201 cgttcttcct ctctcaacac aagcacttga gactactgga agtagactaa aaggaaacga
     1261 ttcctcgata gtccaaccat cccttttcta ttgatgccgt acgctttatc gagacttcat
     1321 tcatgccaag agcacgaagc ttctctcttc tcgatcgttc ctgctcatga ttagcagcat
     1381 taactccagt ttttacaacc cttgtagtcc caataactcg tttaaaaaca atcttcccct
     1441 catcaatatt gtctttataa attaaagaaa taatattaat tacataggaa acaaaaactc
     1501 ttgagttttc caactgcaaa aatgatgatt ctatatcagg tttttttgac ttttggtcaa
     1561 aaataagaac agtgaactta tcgccatctc ttgtaatcaa tacaagatca caagatttat
     1621 tcaccccatc gccattagac ttgtcaaagt atggcgacaa ttgagaaaat aaagcgccat
     1681 tttctttaga gtttttcttg cttgaaaaat ccaaagtgaa agcaatcgaa tcatcaggta
     1741 tttcttttat agttaactct tttatttcac taagctcacc atcttcacga acaactaaca
     1801 ccgaagagtc aggagatgga gttgccgaca aatcaaacaa aacatcttta tttaaaacat
     1861 caataaacct ctccagcata ttagagcccc tcttctaaat atgtatacaa gagatcagcc
     1921 ttgttttcta tatcattaat aacattatca aaaagaaaag cattcacccc atacctattc
     1981 ccttcaacct cagagatggc accatcatta ccgatagtaa aaccattaac ctctgacgaa
     2041 aaaatcaaat ctgcttcttt gtatccaagt tcagttaatc gtgatttatc tttcagctgc
     2101 gaagccatta ttctattatt aatctcttta acgatataat cactatgcgt tgtgattata
     2161 attttaactc cgcaatttga aagtcttaca agcaactctg ccattttaat ttgattatgt
     2221 ggatgcagat tcagctctgg ctcatcaatt atcaagtaag agttattaga catgtagtat
     2281 cttacatata tatctaatag aaatagtgct ttgttagatg ctgatgagag agaaagtggc
     2341 attgacactt tatctccatc actgcaagaa actgtaaaaa tagcctcacc gtcagatgtt
     2401 gagtatctac caccagtaag tgactctagt gtttttataa catcagttcg ctccttagat
     2461 gcccttctaa caccatttgc cgtcattata tgcttcattt ttttcagatc agcaaagtct
     2521 cttattatat ttatattgtg attaattggc tccgagaact tagcaacttt ctggctcata
     2581 atgtcatcaa aagacagtaa cttcctcgta gacaacttac tccacatgta agaatcaaca
     2641 atattactac gattaccatc aatctccttt tgaaacaagg atattccagt acgctcagat
     2701 gttattataa atgcgttatt agctgcagag tctaaaacct cattaaggaa aaagaaatta
     2761 aataaaatat ttaaataatt tgaagcgtct ttttccttca gatcaatgac aggactccct
     2821 gactcattat tctttttgga tgaggtaact gtaaaatcaa tacatgtatt gtttttttct
     2881 tttgtatatt taatattata ttttcactga cagaaatatt tacattaact tcagaattaa
     2941 caactctatc tttaatataa gagtcaatca cactaatttt tgatttagaa aacatacctg
     3001 aactatcttt gaagaatgca ggcaagcttg atgaaacctc ttcattaact gatttaacaa
     3061 gagaatcagt aaaaacgttt gtgatgtcgt acctggcagt tccgtttaaa accaggttgc
     3121 tagatactga ttttggtatt tttattttct ctctaaatat gtcattgtac ctactaatag
     3181 cagcgtatgt gctataactt aggtatgttt tacccacatt atttggccca aaaataacag
     3241 taatgttatt ggtttttatt ttcccgcttt ttataaagcc gatattttca aactctattt
     3301 ccattcgcat cacccactaa gtatgttatg cttttatcct tagcaatatc catgctaact
     3361 atacctacca ttacaagata ttcatacatg atgatttaaa aaccactcct gaatgagcaa
     3421 aaaactactg gatttaccat aacgcgtcat tacacgcacc gctaaaacgg cctcagaacg
     3481 attctggggc gtaacccatt aaatcctacg tcttaccccc tgaaaacgcc tcaaaatcgc
     3541 tccagggcgt tttacgggca tgaatcgtta tgcaccagac tgactggtgg cagatttcag
     3601 cctgaattta ggccagacga ctcgaaaccc gcaccaaacc cgactgaaaa cggtgaatgg
     3661 ggacgcaatt tattgcgtgg ccgtgaggcg ttgccggcac agccggaaaa accgttttca
     3721 acaccttcag gaatcgggcc catcgacagc cggtgaatcg tgtggcaagt cgccggacga
     3781 ctcaccacac gattcaccgg cgactcttca ctagagtcgt acccagagtc gccacgtcta
     3841 aaaaacaacc aaacggggag tcgggtctag agtcgggtcg ttattaactc attgttttta
     3901 tagtcctgag tcgttaccga ctccatgacg actcgccggg gactctatga cgagtcgtca
     3961 tagagtcgga tctatgtaaa taaaatttaa aaaacgaaat ttcaggaaag taactaactg
     4021 atattaaata caaatccgca aaattttaat tttgcgtagt gtgtggatat ttttagtggt
     4081 gaggagcgtt cagagatctg gcgattttgg gaaggttcag gaactccccg ggatggccgg
     4141 agaggaaaac tcaagcatgg caggatcagg attttttcca gaatttccac catggcgccg
     4201 gggattcagt taattttgcc tggtgatttt caagaaggag catggcctgt ttcaggctgt
     4261 caatgtgcga atccttgggg tcggttccgg ctgagggcga aatgacaccc taagctttcg
     4321 gttccttggg ccaaagatat tcgccagtca gtagaatgtg cgcccagccc aatggggata
     4381 tgtggggaag aaattcaggg ggaacatcca acccttcgtt ccgccgctcc gtgacggcat
     4441 gaccaagatg gacggtattc cagtaaatga tcaccgcagt caataaattg agcccagcga
     4501 ttcggtagtg ctgcccctct gtcgtgcgat cgcgaatttc cccctgcctc ccgatacgga
     4561 gcgcattttt gagcgcatgg tgggcctctc ccttgttaag accgatctga gcacgccgct
     4621 gcatgtccgt atccaggatc cactcaataa tgaaaagggt ccgttcaata cgaccaactt
     4681 cacgaagcgc aactgcaagg ttgttttgtc gtgggtaaga agcgagcttg cgcaggagtt
     4741 ggctgggcct gattttgcca gcggtcatcg tcgcggcaca acggaaaata tcaggccagt
     4801 tcgcaacgat aagatcctcc cgggcttttc cacctaccaa cttgcgtaac tccctggggg
     4861 tcgtatcggg attaaatacg tacaaccgct tcgatggcag atccctgatt cgcagaacga
     4921 gattgtagcc gagcaggcta ctggctccga acaaatggtc ggtgaatcct gctgtatcgg
     4981 catactgttc gcgaacatgg cgaccgacct cgttcatcag tagtccatcg agaatatacg
     5041 gtgcctcgct cacggtcgcc gggatcgact gacaagcgaa tggcgcgaac tggtcgctta
     5101 cgtgagtata cgctttgagg ccgggaacag aaccatattt ggcattgacc atgttcatgg
     5161 cttcgccatg ccgcgctgtc gggaaaaact gaccatcgct cgatgctgac gtgcccatcc
     5221 cccagacgcg tgacatcggc agtttaccct gcgcggccac cacaattgcc aatgcctggt
     5281 tcatggcttc gctttcaaca tgccagcggg caaggcgtga gagctgccag taatcatgcg
     5341 tgtttgtagc ttccgccatc ttacgcaggc ccagattgag cccttcagcg agcaggacgt
     5401 tgagcagacc gatccggtcg cgacatggag ccccggttct cagatgggta aacgcatctg
     5461 tgaaaccaag ggctgcatca acttcaagca gcatgtcggt aatccgaacg gacggcattc
     5521 ggcgatacag atccagtatg agtgcctcgg caccatccgg cacgtctgct gtcaacctgt
     5581 cgatccgcaa cgttccatct tctatgctac cgtgcggaat agtgccgtta cgggcagccc
     5641 gggccagccg cttaagagcg atcgtgagtc gcgcctttct gtctgccagc caatcctgtg
     5701 ggttggaagg cacggccagt tttgcatttt cctgcgccgc gatcatcggc accagtacct
     5761 gcttgaggtc accatagcgg cgcgaatgag cgagccagac atctccggaa cgaaaagcat
     5821 cccggaggtg aaagagtacc gccacttccc aaagacgggt atctcctttt tcctgagctc
     5881 gtaaatgacg gttccatttg gagctgggcc gcaggaaacg cctttctggc gatgcaacac
     5941 ctttcatctc tccgatcgac aaagctgctg ctaccaatgg tccggcgacc ggcgcggctt
     6001 cgagcttcag acagcgcaac atgcggggcg cataacgacg aaagcgatgg tatccctgcc
     6061 cgacatatgc aagaggctca tcggctagcg tgttgctgag ttgagtccct gtcgctacca
     6121 gttgagcgag ccggtcccat gcaaccgaac tggcgacagc catctccagc ggggttccgt
     6181 cactgcgggc ctcaagcaac gaagctccca gcgcggtgaa ggtacggatc gtatccgtga
     6241 gtgtggcttt agagccggaa attgtttcgt catgctggcg cttcgcttcc cgccaggttt
     6301 ttcctacgat cctgtcatgg gtttcgacta tggcatcagc aatcgccgct tcccactcca
     6361 caacacagac ggcaaggatc gcccagcggc ggtccgaagt gatgtcacgc aaaccgtcgg
     6421 tgaagtagcg ttcaccctgc cgacgcagcc gggcaatgcg atgggcaggt atgctggcca
     6481 aagcactatg attgatattc agggtacgca gaaattcgag cctgtcgagc aaacggttag
     6541 cagcagccga gttgttacca acctcgaagt tgcgaagcca gatgaaacga ctgatattgc
     6601 cggcgagcat ttcactcaga agtttgtcca ggtgatcgcg aacatccgct gttaaatttt
     6661 ccgcaatccg cgtttcaatc cgccgctcag cggcgaccag agcatccgcg cacaagcgct
     6721 cgattgtcga tactgcgggc agaatggtgg aagtttcccg acaccgcaca ataaaacgat
     6781 gagcaagatc ctcgtttgat ctggcatctt cggcctggcc gaaagtccac tcccgcagat
     6841 cacgggcacc acggcccgtg aaggtcttgt agccgtaaat ttcgcgcagc gtgtccatgt
     6901 gctgctgacg ggtttggcgc cgtgtggcat aagtgagaag cgcatcagcc ggaactccaa
     6961 gctgagcacc gacgaaggaa aggacttcac gcgggatcat ctcaccagga gccagtgcac
     7021 ggcccggata tcgtaaggca caaagttgca gggcaaagcc aatcctgttt tccggtctgc
     7081 ggcgctgcct aatgttttcc aggtcatcat cgcccagcgt gtagaacttc agtagcgaca
     7141 gttcgtccgt gggcagatcg aacagcgctg ctcgctgccg ttcggtgaaa atatggcgtc
     7201 gtgacataca aattcgtccc ttttgaagta tagtctgttt tggacaacag ccagcccata
     7261 taaatcaggg cgttccgata caaaaatcca ggagggttca attgggacat cgtgccgcca
     7321 tttactgccg ggtttcaaca gcggatcagt cttgtgaacg ccaggaattt gatctgcgag
     7381 ccttcgccgg ctgtgccggc tacgacgtgg tgggaatatt taaggaaaca ggttcaggaa
     7441 ctaaactcga ccgggccgag cgaaagaaag tcctggcgct tgcccagtcc agacaaattg
     7501 atgcaatcct ggtcactgag ctttcccggt gggggcgctc gacgctcgat ctgctcaata
     7561 cgctacgtga actggagaac tggaaggttt ccgtgatagc catgaatgga atggcgttcg
     7621 atctttcgtc gccgtatgga cgaatgctgg cgacgtttct ttccggcatt gcggagtttg
     7681 agcgggatct catcagcgag cgggtcaagt caggccttgc tgttgcgaag gcacgtggta
     7741 agaggcttgg tcgtcaggcc ggagtgcgac caaaatcaga ccgacttttg cctaaggtgg
     7801 ttgcgatgag ggccgaggga cgcagctatc gctggatcgc acgcgagctc ggtatcagca
     7861 agaataccgt cgctgacatc gtgcaacgac acagagctaa cgcttagggt gtcatttcgc
     7921 cctcag
//
