LOCUS       NZ_OW968014            26835 bp    DNA     circular CON 19-JUN-2024
DEFINITION  Escherichia coli isolate 58 plasmid P3, complete sequence.
ACCESSION   NZ_OW968014
VERSION     NZ_OW968014.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA8065752
            Assembly: GCF_905332395.2
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Alioto,T., Alioto,T. and Gomez Garrido,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2022) CNAG-CRG, CNAG, Spain
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_905332395.2-RS_2024_06_19
            Annotation Date                   :: 06/19/2024 11:24:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,874
            CDSs (total)                      :: 4,756
            Genes (coding)                    :: 4,561
            CDSs (with protein)               :: 4,561
            Genes (RNA)                       :: 118
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 195
            CDSs (without protein)            :: 195
            Pseudo Genes (ambiguous residues) :: 0 of 195
            Pseudo Genes (frameshifted)       :: 76 of 195
            Pseudo Genes (incomplete)         :: 122 of 195
            Pseudo Genes (internal stop)      :: 55 of 195
            Pseudo Genes (multiple problems)  :: 49 of 195
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OW968014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26835
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /isolate="58"
                     /isolation_source="Hospital Universitario Ramon y Cajal
                     (Madrid)"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="P3"
                     /geo_loc_name="Spain"
                     /collection_date="2018"
     gene            420..1370
                     /locus_tag="LQ149_RS24085"
                     /old_locus_tag="AI2894V1_4647"
     CDS             420..1370
                     /locus_tag="LQ149_RS24085"
                     /old_locus_tag="AI2894V1_4647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zincin-like metallopeptidase domain-containing
                     protein"
                     /protein_id="WP_082242812.1"
                     /translation="MTMNLHTQTSAPNPAAAASVSPLEQSGSTKTKFSKNKTKTDIYQT
                     VTDSIIEALEMGVKPWVCPWKRNGSVSGIPSNFMTGTAYSGMNIMLLWCSAAKQGFNDS
                     RWLTYKQAQEQGAQVRKGERGTTAIFYKTLEKEAEDGEIEKIPMLKTFTVFNVEQIDGL
                     TLTEEDTAEPVSEFDPLPHVEALFQRTGANITERGQQAFFRPATDEIWLPERHLFTDAA
                     NFYATGLHELVHWTGAKSRLNREKCGRFGSEGYAFEELIAELGSAFLMADLGITGDVQH
                     ESYIASWLKSLRDDKRYIFKAAAAASKAHRYLMEC"
                     /name="zincin-like metallopeptidase domain-containing
                     protein"
     gene            1669..2022
                     /locus_tag="LQ149_RS24090"
                     /old_locus_tag="AI2894V1_4648"
     CDS             1669..2022
                     /locus_tag="LQ149_RS24090"
                     /old_locus_tag="AI2894V1_4648"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726759.1"
                     /translation="MTMYQDLPSVLNLINCESPFPCNQASCAQGIADKNSFVEFIVTHK
                     SAGNLHEWNLSYVDRFNRLIKVFYHDHMILHARINMKTGIVNLIAYTVFTDKISSLEAE
                     YLVEQIRQHLDHF"
                     /name="hypothetical protein"
     gene            complement(2068..2649)
                     /locus_tag="LQ149_RS24095"
                     /old_locus_tag="AI2894V1_4649"
     CDS             complement(2068..2649)
                     /locus_tag="LQ149_RS24095"
                     /old_locus_tag="AI2894V1_4649"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726758.1"
                     /translation="MERTTINFRINDDTLLAQFNHAMAKEQKKYKFATDGIRTIKDLEI
                     IFTASKIKNFRDNEHYLIASLAQKQSPLILNVLNELKDKFEKIYQEERNITGQIIFFKK
                     ILEQVEYHDKTQDINVLISPHVMLFINITALADNIIKQLRVQYLNGSIDETTLLIKRNK
                     ILKQYAALREKLHEMKQERKKLFKKVKDNL"
                     /name="hypothetical protein"
     gene            complement(2649..3101)
                     /locus_tag="LQ149_RS24100"
                     /old_locus_tag="AI2894V1_4650"
     CDS             complement(2649..3101)
                     /locus_tag="LQ149_RS24100"
                     /old_locus_tag="AI2894V1_4650"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_082242810.1"
                     /translation="MFRLATPEDYEYLPDIGLYELTFDKRPVQGVRCEDPKQGAADYNN
                     FRKKFKAVIHKEKQRRKNFYQLTEISWNAVFDWAIERGTQEECRLLQAMYHAENNKKYQ
                     QLLLELSKHYGFIKESNLLIPLGLILCNQRIADTEKLIANSVKAGI"
                     /name="hypothetical protein"
     gene            complement(3104..3670)
                     /locus_tag="LQ149_RS24105"
                     /old_locus_tag="AI2894V1_4651"
     CDS             complement(3104..3670)
                     /locus_tag="LQ149_RS24105"
                     /old_locus_tag="AI2894V1_4651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012368887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="WP_223364411.1"
                     /translation="MKILIFLVLMIMSNTSFSKSLFIGDSLTYSLASSFSKIEPVDAKF
                     LESTGLKSDNILSWTDYIETMDLSNYDRIYIVLGINDMINENDEILYQDRVDTFIMSLL
                     NKNKNIIWLLPPVLKNAKHESMLLYTRSIIKAACIEHSVDFFDMRDVLGYNFMQTVNDR
                     NIRTDDGIHITPYGADRVITNLLLR"
                     /name="GDSL-type esterase/lipase family protein"
     gene            3769..3999
                     /locus_tag="LQ149_RS24110"
                     /old_locus_tag="AI2894V1_4652"
     CDS             3769..3999
                     /locus_tag="LQ149_RS24110"
                     /old_locus_tag="AI2894V1_4652"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_029403597.1"
                     /translation="MENVNKPNNAIEEKIENLKSKLTELDEKREKLITRIDKLESQMNA
                     EKAQKILDDKRQELENLLGKENLDLLFGSKK"
                     /name="hypothetical protein"
     gene            4773..6887
                     /locus_tag="LQ149_RS24115"
                     /old_locus_tag="AI2894V1_4653"
     CDS             4773..6887
                     /locus_tag="LQ149_RS24115"
                     /old_locus_tag="AI2894V1_4653"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_087726757.1"
                     /translation="MDQGLYGFRQFGYVIDNFSSVFLYHHWLVLFVIWAIFVLMVSIIV
                     RSLNHVIFIGMSDDDREDSRNVEVNGKRQKRGVFASMQYDKPYFSLLLLRQAGFFIKIL
                     LIFIIAFMTAFFIVTLISAFFDIDYVITPYKAQYYLLTKTNMYGLSIILVGSLVGYIVS
                     AFLYHSFIKPFFGEIDLIFNEEAISRRESSKMRDDKLTDIRNFNFKDSINYNPVDYFHE
                     AKSKKSIFLGIDENNKPILIPKLKWDETNIQVIGKMGSGKGVLSTVALVQCVELYNDIN
                     IIFDPKNDEWAYHVFKHFFKDDLLYIDLNRGQLPQVNPFKGANSDEINELLVASFGLGE
                     KGTDADFYKTGDRKVCRDLSQHFTQGTDLRGLLSIALNENFRKSYDRTGENFFNLLEEL
                     GQLDSISAHDGIDLVDILNNQNKKIIYITGSLRDEVVVKAQKMLFLRMVQILEKRNRNK
                     DVTHVNIMLDEIKYLISKSALEAMGTLRDKKANILFTHQSRGDLEVSTKEIDGQTARKV
                     IEDSAGLRWIYRTDNYESAKWASDFTAGGLVDVERRNLSVNQSNVEMASKEATIFKQKA
                     NYVDISVIQNLPSRCGLIVGDGQLARLAYSSPILVEKSDKCVTSFETQAISSREFLASI
                     RETNDKPKTSSDKKVKNNRNTKPVDNPQSGTMVNRERVNSAVDADRVDSVMAELTMPDD
                     NHGDNYHEHS"
                     /name="MFS transporter"
     gene            6874..7878
                     /locus_tag="LQ149_RS24120"
                     /old_locus_tag="AI2894V1_4654"
     CDS             6874..7878
                     /locus_tag="LQ149_RS24120"
                     /old_locus_tag="AI2894V1_4654"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_082242808.1"
                     /translation="MSIADYGSLSNQKRLEQRQFNQHKILSFLAQERSVTIDSLSRLFD
                     FSANQKIYLLLKNLINNELVTYFEDGFLGRTKRFYHLTAQGQAFAEQELGITPRFNGLS
                     RRAHAPSALLHTLEMQNYTALLMKAGAKVRYLHLPDKIMDYWYGGTAAEVERTFKSQKR
                     YRDIFRNYCLRMRRNDPIINTVMYILPDSAMRDKAAALFYSFDELMIEGILTDVRTYTG
                     RFLFATRAEYEAYLTAFPQSGVRVEMKLPNEVWQRWQRHAAQAQLTPEAWLTGILNREV
                     PVVINEPMPYSGDGVLINLTPTKDDYKFWLANADACHTSLSAWCAGKPVHLNL"
                     /name="hypothetical protein"
     gene            complement(7908..8153)
                     /locus_tag="LQ149_RS24125"
                     /old_locus_tag="AI2894V1_4655"
     CDS             complement(7908..8153)
                     /locus_tag="LQ149_RS24125"
                     /old_locus_tag="AI2894V1_4655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005370427.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_029403600.1"
                     /translation="MIPERLKTARKKRHYTQELLAIKAGIDESTASSRISQYENGYSVP
                     SYQLMQKIASILQIPTCYFYCDDEELADYLINYYRR"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(8210..8530)
                     /locus_tag="LQ149_RS24130"
                     /old_locus_tag="AI2894V1_4656"
     CDS             complement(8210..8530)
                     /locus_tag="LQ149_RS24130"
                     /old_locus_tag="AI2894V1_4656"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_029403601.1"
                     /translation="MKKNFFEYIEEAKKLTICDSYRKIAQYLDAPPIKISQWKQGKGYV
                     SPAECAHLARLLGITTEEIAYVIKAEREEIPEKKEYWYKEAEIFSRPINPPESLKLKNK
                     KS"
                     /name="hypothetical protein"
     gene            8636..9169
                     /locus_tag="LQ149_RS24135"
                     /old_locus_tag="AI2894V1_4657"
     CDS             8636..9169
                     /locus_tag="LQ149_RS24135"
                     /old_locus_tag="AI2894V1_4657"
                     /inference="COORDINATES: protein motif:HMM:NF021981.4"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
                     /protein_id="WP_157673318.1"
                     /translation="MITNNTLKRKFLNTLLFFGVLSGCVMLYQHYFVVNFTKSMPLGVY
                     FKSYPASYTKNDTVLVCLDDEIARWSVDHHIIADGLGCRHSAPLLKKIVATEGDRVTVT
                     HKGIVVNDVLVPNTAPIARKIKQWNIIDREILLKSTEYIVVANQNNLSFDSRYFGVVTD
                     RNITAKIRPFYLFD"
                     /name="S26 family signal peptidase"
     gene            9260..9799
                     /locus_tag="LQ149_RS24140"
                     /old_locus_tag="AI2894V1_4658"
     CDS             9260..9799
                     /locus_tag="LQ149_RS24140"
                     /old_locus_tag="AI2894V1_4658"
                     /inference="COORDINATES: protein motif:HMM:NF013618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_135180852.1"
                     /translation="MPSVSACAPEIAADTLQKIIMVESGGNPFAVNVNKLSAGSQPKPK
                     NVADAVAATQYWIAKGYSVDVGLMQVNSRNFKMLGITDTDLGSVFEPCNNVKYGATILL
                     SAWNMTSSKEHQNDRLMKSLSIYNTGNDVNGFKNGYVSKYVGRNISGSLAKTVVTPYNA
                     DSSVGFNADSFYGDDL"
                     /name="lytic transglycosylase domain-containing protein"
     gene            9796..10740
                     /gene="trbB"
                     /locus_tag="LQ149_RS24145"
                     /old_locus_tag="AI2894V1_4659"
     CDS             9796..10740
                     /gene="trbB"
                     /locus_tag="LQ149_RS24145"
                     /old_locus_tag="AI2894V1_4659"
                     /inference="COORDINATES: protein motif:HMM:TIGR02782.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer ATPase TrbB"
                     /protein_id="WP_087726755.1"
                     /translation="MNTGDDKKISDLAKMLWREFDIIAPYLRDETTIEIMLNPDGKIWV
                     EQIGKPMFSIGEMSLYNAQSLFATIAHSMGKTIDNRHPCLEGTLLINDARFEGFYPPVS
                     SAPTFAIRKKPKKIFSLDDFKLTENQKSTMVTWVKERKNILVVGGTSSGKTSFSNAFID
                     LMAQFTPDDRIVILETLDEIQCRAKNYSKLIETMDVTMNQLLRGVMRYRPDRIIVGEVV
                     DAAALSMLKAWNTGHDGGLCTIHADSALEGFDRLYDLIEESGINMSERVNRLIGRAIDG
                     VVFLKREQGVRVVKEVANVTEFNGSEFVLDYVN"
                     /name="trbB"
     gene            10750..11109
                     /locus_tag="LQ149_RS24150"
                     /old_locus_tag="AI2894V1_4660"
     CDS             10750..11109
                     /locus_tag="LQ149_RS24150"
                     /old_locus_tag="AI2894V1_4660"
                     /inference="COORDINATES: protein motif:HMM:NF016820.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_087726754.1"
                     /translation="MLEKYYYSQSRLTQQLIVLGALLLVCMLLSSHAMAGQTQGLPWES
                     PLDKIKNSITGPVAGAISFLGICVAGMMLIWGGEMSDFTKRIVYVVLVISLILGASVVI
                     NMWQGNGALIPLSMV"
                     /name="TrbC/VirB2 family protein"
     gene            11115..11435
                     /gene="trbD"
                     /locus_tag="LQ149_RS24155"
                     /old_locus_tag="AI2894V1_4661"
     CDS             11115..11435
                     /gene="trbD"
                     /locus_tag="LQ149_RS24155"
                     /old_locus_tag="AI2894V1_4661"
                     /inference="COORDINATES: protein motif:HMM:NF010395.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbD"
                     /protein_id="WP_032300801.1"
                     /translation="MKTQEPLVSFIIHRSLNRPDLVFGCERKPLYCLGLIAAVMIFSSY
                     NLYIAGAGLVVFCVGVYLLRRMAKADPFMSLIFQRAIRYRYYYPARSTPFATGAKFRRK
                     KQ"
                     /name="trbD"
     gene            11432..13933
                     /locus_tag="LQ149_RS24160"
                     /old_locus_tag="AI2894V1_4662"
     CDS             11432..13933
                     /locus_tag="LQ149_RS24160"
                     /old_locus_tag="AI2894V1_4662"
                     /inference="COORDINATES: protein motif:HMM:NF015118.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_082242806.1"
                     /translation="MKLYKKQYNTSLSFADLLNFGVMITPNLMLGKDGSLTAGLVYTCW
                     DYENSDNSELNDLVNALNAAYLRLGTGITLHFTVIRSETSEYPQPEKSHFTSLLNKLID
                     EERRIKWESAGAHFSSVLSFSITYLPESMSKSRLSDFFVTDESGTKKSKSLTDKHIEYF
                     ESVISELSGQLSGTFTLHRLGVRHDNATGVVYNDLVQYFNHCISGDNYPVIHPDNQFLD
                     AVLSTDDFYTEPRLKIGNKYISVLCIDAYPASSVMGMLQSLSNLPCEYRWTTRAIFLDP
                     IDADKQIEKYRKSWGQKVRGFVDQLMGKHSDNINYDAATMKEDAQIAKGENNSNTVRYL
                     YLTPTIVIMDEDIDRLDETTNLIRTTIKNVVNFNARIETVNAMDAYLGSLPSHTYENVR
                     RPLLHTGNMTHIVPCSTLWTGEETSPCPFFPPDSPPLMKVSTTGNSEFNLNLHEDDVGH
                     GIIGGKTGAGKSSLVTLISSQYDRYPDSQVFTFDKGRSAKVFCKLSGGKYYDIMTGEHS
                     LNFAPLARIDEPSEFIWAFEWLQDIAEINGVKLDSEKVKKLNEALKIVSRMDNKDGQYR
                     NIDSLITKLQDRELKDLFSQYGSGGAYGEVLNQPQEQITLSNFTVFEYGELLDRGNKIK
                     LPVLFYLCHLIERQLDGRPTLVNIDEAWKFLDEPVAGKRLLQWLREWRKSNAAVVISTQ
                     NLHIIEKAFPLVFSEIAMACPTKLFLSNPAAEEEVSINAYKILGCKAAEIRRIRHLTPK
                     REYFVKKGDFRRTFSLDMVEGDIGLATVAASSKKDLKEIDKLDFEHSSEEELLHQWLDF
                     KGVDSGYVQYLTDRLKSRGEI"
                     /name="hypothetical protein"
     gene            13930..14658
                     /locus_tag="LQ149_RS24165"
                     /old_locus_tag="AI2894V1_4663"
     CDS             13930..14658
                     /locus_tag="LQ149_RS24165"
                     /old_locus_tag="AI2894V1_4663"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726753.1"
                     /translation="MKKILIAGVFAISTFTTLNSFAWHGVATEGTQWLNNLQLVKQVEE
                     QMRTVKNQIQDLQRLPSDVLNMGSNKLKVLETFNDLKRIYQEGQNIAQAGRDVAKYYKD
                     MGNIDIADALKNGNYPQLFNQWSHQNHDTVKGILEQNKLSMDWFNDRQGEVAGYNSMLN
                     SADGTVSALQAAGKIANAQLDSLSQLGQLQMAQNNLLASQAAVQQSEKDAERADTIRRS
                     EMNVIINSDNNTAADFLKRD"
                     /name="hypothetical protein"
     gene            14661..14903
                     /locus_tag="LQ149_RS24170"
                     /old_locus_tag="AI2894V1_4664"
     CDS             14661..14903
                     /locus_tag="LQ149_RS24170"
                     /old_locus_tag="AI2894V1_4664"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726752.1"
                     /translation="MKLITTGLSFFLIITVVSTGYLWKQNKELHYQINELSTVVAEQRV
                     AVQGCLKEKTDTQHRGKANFVIPDDSGNAEDWLKR"
                     /name="hypothetical protein"
     gene            14922..16529
                     /gene="trbL"
                     /locus_tag="LQ149_RS24175"
                     /old_locus_tag="AI2894V1_4665"
     CDS             14922..16529
                     /gene="trbL"
                     /locus_tag="LQ149_RS24175"
                     /old_locus_tag="AI2894V1_4665"
                     /inference="COORDINATES: protein motif:HMM:TIGR02783.1"
                     /GO_process="GO:0009291 - unidirectional conjugation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbL"
                     /protein_id="WP_087726751.1"
                     /translation="MKKIIFLFCVLLMPFLTHLAYADDVSGLTGEWKSPEEVRRLIDES
                     RRETALINQYTNECAKGNNQSCIQLETIKSKNSKINLDANFVKTFSDSFQQEIKKWLPP
                     LQKAAKYLLFTLGIIALVLKMVPLVLKGADLGEIIKELIIFVLIIGIWLAFIINAKEWT
                     DAIINSFMKLAQLANQTSMQATPVGILKQGFIVVGKVFTDPINPITLLTQVICALIIMI
                     IYAKIAFYLLKVMLETYIVSYGGIILLGFGGIAFTSDYAKRYFTYVISCGIKLFMTLLI
                     IGFGGNFIASFLTLNFTEFANCVAIVAVVVMLMMLAEGIPDMAQSMVTGASLGNSNMNI
                     GGSLATMAAAATAFTAACYAGAAAFKAAGAANAAGGGGAATGGLSGGDLANALSKGGGS
                     GVAGGGGSGGSSSLPNGGKSGAQLVKEGKVQSPNKNTGNTATGTESGKPQQSRTGAALK
                     AVAKSVGEGILNKAAGSRGSTAANITRAALNHAAQSQQSTESPRKPIASPYAKSTGNNS
                     SGTSKMPNKGNNDTGENQ"
                     /name="trbL"
     gene            16526..17170
                     /locus_tag="LQ149_RS24185"
                     /old_locus_tag="AI2894V1_4666"
     CDS             16526..17170
                     /locus_tag="LQ149_RS24185"
                     /old_locus_tag="AI2894V1_4666"
                     /inference="COORDINATES: protein motif:HMM:NF016238.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_071434332.1"
                     /translation="MSDDKFKKSSGWNSFLGKTKEQVTFYRWTTILCAVAAIISISGCI
                     YFSSQVKYVPFVVEVNKEYAPLQVHQLESLGQSKDAVTRSQLATIIKNMRVVYAGDKEA
                     QLDAIKSVYYFIKTNSQPYKYVQEMFSVDDPMNQKFLNQVEIKAILPLSKDTWRAEWVE
                     KKAMPDGKNVLSRNYSAVIQVEYADTISAEMIINNPIGLYLKNMQITEEYK"
                     /name="type IV secretion system protein"
     gene            17182..18096
                     /gene="trbG"
                     /locus_tag="LQ149_RS24190"
                     /old_locus_tag="AI2894V1_4667"
     CDS             17182..18096
                     /gene="trbG"
                     /locus_tag="LQ149_RS24190"
                     /old_locus_tag="AI2894V1_4667"
                     /inference="COORDINATES: protein motif:HMM:NF015487.4"
                     /GO_process="GO:0009291 - unidirectional conjugation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbG"
                     /protein_id="WP_087726750.1"
                     /translation="MKKTILFTSLLISGVALADPVVPSVSNIERINTGATSQPTTPQQA
                     MPSSMLLGGKDLPLSRKEQQAIKTANQWVNGKQYISNGGQEVVYTYGAGQAAIIATPLK
                     LSVFELESGERIVNEGIQLGDSVRWHATPVKQGNQTNVIIKPTDTGLSTDLVVVTDRRT
                     YHIKLISNSKNYTPLVKFSYPEDENQKAWNAYYQNSGADNSSISLAGNKTGLAPVNFDY
                     TIKGDNKMKPLRVYDNGSQVFIQMDGKLQETPALFVINGSGKQQLVNYRYVDNTFVVDR
                     LFNKAVLTLDVGGDQEKVTITKG"
                     /name="trbG"
     gene            18100..18546
                     /locus_tag="LQ149_RS24195"
                     /old_locus_tag="AI2894V1_4668"
     CDS             18100..18546
                     /locus_tag="LQ149_RS24195"
                     /old_locus_tag="AI2894V1_4668"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726749.1"
                     /translation="MKYKLFFAFVCMVLAGCVSKPNISSYDGTQGTIGKNSVQKMLYGV
                     DVIFSKLHSKNTIFYIEDSHSDIANAFIENIKRKGFIVIVTNKEDKINYKKINMGMIVK
                     KITPDIYSLSIITDKYRINQPYDYQLNKIGEVSIQNKTEDVNHG"
                     /name="hypothetical protein"
     gene            18539..19753
                     /locus_tag="LQ149_RS24200"
                     /old_locus_tag="AI2894V1_4669"
     CDS             18539..19753
                     /locus_tag="LQ149_RS24200"
                     /old_locus_tag="AI2894V1_4669"
                     /inference="COORDINATES: protein motif:HMM:NF015688.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="WP_157673317.1"
                     /translation="MANPSQNKKLTKKQKLLMTIGFAAVLIIFVVFISIMSLGTNTDSQ
                     TQSYEDAKDKSGDPADPSYEANLYRSRFRENTDLQTPPATPDKAPSATGTIQTANVSQP
                     QSNSTQTQSQERDQFAENVLRMKQQAYMEALNSKTTVRVDALSDNNSPERGSSAPDYAS
                     IAEQLAAASKEGNGELYANMQQNKEKFVNTERTFGYSTQTREAALSQTEIKAGMILPAV
                     LVTEINSDLPGLITAQITEDVRDSLTGRKILIPRGSKLIGSYDSQVAMGQERVLVVWNR
                     VQFPDTSTLALGNMGGTDGMGQSGFNDEVNNHYLRIFGNATLLAIIGAGFQLSQPDNNS
                     NNGNNGMTAREQMIAEIGRQWSTVGTEVVRRNLNIQPTLHIRAGYKFNVLVNKDIILPE
                     YQPNH"
                     /name="TrbI/VirB10 family protein"
     gene            19776..20264
                     /locus_tag="LQ149_RS24205"
                     /old_locus_tag="AI2894V1_4670"
     CDS             19776..20264
                     /locus_tag="LQ149_RS24205"
                     /old_locus_tag="AI2894V1_4670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_082242801.1"
                     /translation="MASRGVNKVILIGNLGQDPEIRYMPNGGAVANLSLATSETWRDKQ
                     TNEMREKTEWHRVVIFGKLAEIAGEYLKKGSQVYIEGSLQTRKWQDQSGQDRYSTEIVV
                     NIGGSMQMLGGRNGDAPATDQSGQGQTQESPKFSGGDAPAPAKQTNEPPLDFSDDIPF"
                     /name="single-stranded DNA-binding protein"
     gene            20332..20553
                     /locus_tag="LQ149_RS24210"
                     /old_locus_tag="AI2894V1_4671"
     CDS             20332..20553
                     /locus_tag="LQ149_RS24210"
                     /old_locus_tag="AI2894V1_4671"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1496 domain-containing protein"
                     /protein_id="WP_082242800.1"
                     /translation="MQIAKLTCLIIFGLSALTATAAESDTENNNQCVYQGQSYGIGSPI
                     NIDGHSYICVKKANKMMWLPAIDAQRYL"
                     /name="DUF1496 domain-containing protein"
     gene            20572..20922
                     /locus_tag="LQ149_RS24215"
     CDS             20572..20922
                     /locus_tag="LQ149_RS24215"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088207275.1"
                     /translation="MILFFERSKPLTHKIDNILLSEIKKREPLKYHSFQLTNFISGVLF
                     LCCLCSFVSYIVFSVFLQNSGVEIDPSVTKIFAKVIVGFFLSGFACWFLRTYLYTELEH
                     QIMKIWYRQASS"
                     /name="hypothetical protein"
     gene            21627..21866
                     /locus_tag="LQ149_RS24220"
                     /old_locus_tag="AI2894V1_4672"
     CDS             21627..21866
                     /locus_tag="LQ149_RS24220"
                     /old_locus_tag="AI2894V1_4672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726764.1"
                     /translation="MGTLTVRPQPEHEDALAAVGALLQEKRASQTLLKSLMAYEPHCKE
                     IAQLKAALHKAEKERDMYKDKIERFKAAQLALFE"
                     /name="hypothetical protein"
     gene            21923..22180
                     /locus_tag="LQ149_RS24225"
                     /old_locus_tag="AI2894V1_4673"
     CDS             21923..22180
                     /locus_tag="LQ149_RS24225"
                     /old_locus_tag="AI2894V1_4673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009047943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_082242798.1"
                     /translation="MLTTFFTSREFNQEIGKAKKAACQGAVFITDRGKATHVLLSIDEY
                     EQISGLNDENIVDALSVPGLSEIDFDTSRLSIFPPDRDIF"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            22180..22608
                     /locus_tag="LQ149_RS24230"
                     /old_locus_tag="AI2894V1_4674"
     CDS             22180..22608
                     /locus_tag="LQ149_RS24230"
                     /old_locus_tag="AI2894V1_4674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011251439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family toxin"
                     /protein_id="WP_070133934.1"
                     /translation="MFILDTNVISELRKAGDGKADAQVMRWLSSVNSRQLYLSVITVLE
                     LERGILRVERRDTTQGKMLRRWMDGHVLPLFANRILPVDMAVVRQCARLHVPDPKPESD
                     TLIAATALVHGYIVVTRNTKDFCSTGVNIINPWEDNGN"
                     /name="type II toxin-antitoxin system VapC family toxin"
     gene            complement(22693..22809)
                     /locus_tag="LQ149_RS24235"
     CDS             complement(22693..22809)
                     /locus_tag="LQ149_RS24235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001584988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="WP_087726763.1"
                     /translation="MDTPLIFSGRQTKEIIGVFAFLAPVKPQNQFPAALWRN"
                     /name="replication protein RepA"
     gene            22884..23810
                     /gene="repA"
                     /locus_tag="LQ149_RS24240"
                     /old_locus_tag="AI2894V1_4675"
     CDS             22884..23810
                     /gene="repA"
                     /locus_tag="LQ149_RS24240"
                     /old_locus_tag="AI2894V1_4675"
                     /inference="COORDINATES: protein motif:HMM:NF014444.4"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiator RepA"
                     /protein_id="WP_087726762.1"
                     /translation="MCSFCAIYAQNTVIDSHNQAQEQRSRGIEWRNSYVTNANPVYSAP
                     KECASPPRIITALRKAALTSNPARHPIWRTADRFHAINHQRLPKERAMNEHRARAVNAI
                     CACIADRLNIVTGKVFMTLAQISDSCGLTTYNKDGTPCYSRASRAINEHLEAIGAIHCD
                     RVWDETTGSWIPNLIWVSELFFTLIGYEYGKYEAAQQQQLAWENKGLKEKGEPAISLTE
                     ARRRAKVKHIQTAFEVRAKKRAFKTQLRQARKLAAMEKQKAQAKILNDLVKLYSQDELA
                     AMGHVELKRQVEHRYAAMRKLATAPPH"
                     /name="repA"
     gene            complement(24608..24802)
                     /locus_tag="LQ149_RS24245"
     CDS             complement(24608..24802)
                     /locus_tag="LQ149_RS24245"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726760.1"
                     /translation="MKKFIGKLANFCGGYARLAVIGFVAMFGVIAIIFSLSGAEKIFVV
                     TPIAMMFLFAFLGKYWIEK"
                     /name="hypothetical protein"
     gene            complement(24931..25389)
                     /locus_tag="LQ149_RS24250"
                     /old_locus_tag="AI2894V1_4676"
     CDS             complement(24931..25389)
                     /locus_tag="LQ149_RS24250"
                     /old_locus_tag="AI2894V1_4676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223364412.1"
                     /translation="MLEHKFKTVRELKDALNECPDDAEIDISELPNNISRHGLTTVFDG
                     KKVLICEYHDYEIINKYRNIFSELSKTEQSRCGCVYEMYQRNLSTAIDGYLSELTQEDK
                     RKVIQLARAEFDYISPEEITEAIRQNQEDGYCSHGLDPNCCPLGCGDI"
                     /name="hypothetical protein"
     gene            complement(25395..25673)
                     /locus_tag="LQ149_RS24255"
                     /old_locus_tag="AI2894V1_4677"
     CDS             complement(25395..25673)
                     /locus_tag="LQ149_RS24255"
                     /old_locus_tag="AI2894V1_4677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012368896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stability/partitioning protein"
                     /protein_id="WP_082242815.1"
                     /translation="MDINKLKKHAPIIEPSESKTVNDFIAQGDKKPTKKAESIMVGFRM
                     DEDTLERLDRLTNGLGKKRINILRASLLAFESLSPSDKAKFLIEIMR"
                     /name="plasmid stability/partitioning protein"
     gene            complement(25735..26397)
                     /locus_tag="LQ149_RS24260"
                     /old_locus_tag="AI2894V1_4678"
     CDS             complement(25735..26397)
                     /locus_tag="LQ149_RS24260"
                     /old_locus_tag="AI2894V1_4678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012368895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsA-related P-loop ATPase"
                     /protein_id="WP_036944392.1"
                     /translation="MIIVFGSDKGGVGKTTITANSAVMLQQKTASVALVRTDKNEDLNT
                     WQSLRREQPVPDIPIMTCYGSNTHKEINKLHGVTDVILVDTAGHDSVELRSALLVADVF
                     IAPVSPTSMLEVVTLNKLSSIVNEAKKENTKLKAFALLNRCPTSPFNNDAVKITQYLND
                     DPLLLSPFKTRISNLKAFEKAINEGLGVHELKGKNVGSAKAQLELLFAELIDSVQDS"
                     /name="ArsA-related P-loop ATPase"
     Typing          6884..7875
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 ggcgttttac taaatggccg tggcggggca gacacaaaca cacccccacg gttgaaagaa
       61 acccgccccg ccagacacaa catatagtat gtctgtcagc tgcgaccggt acaacatata
      121 gcgttatcca cagaaacggt ggataagtcg ataggctact gattaacaac aaaatcaaaa
      181 gcaaggtcaa aaccattccg ccactacagc gtaaggggcg ctaagtccgt gtgtgctggc
      241 cgtcattttc tcctgtgttg cctttcccct ccgtatcagg cttccggtaa tcgttccccg
      301 ttacaacctg ttccgcaagg gtatataaac gctccgcgcc cttgcagacc agaacgataa
      361 cggggcgtcg aaccgtcagg cgatacgaag acgaaattca cactgacgga gaaacaacca
      421 tgactatgaa tctgcacacc cagacaagcg cccctaaccc cgcagcggcg gccagcgtat
      481 ccccgctgga gcagtcaggc tccacaaaaa cgaaattttc taaaaacaaa accaaaacag
      541 atatttatca gacagtgaca gacagcatta tagaagccct tgaaatgggg gttaaaccgt
      601 gggtgtgtcc gtggaagcgt aacggttcgg tgtctggtat tccttcaaat tttatgactg
      661 gtacagccta cagcggcatg aatatcatgc tgttatggtg cagtgcggca aagcagggat
      721 ttaatgattc ccgctggctg acctacaagc aggctcagga gcagggcgca caggtgcgta
      781 aaggggagcg cggaacgaca gccatttttt acaagacgtt agaaaaagaa gctgaagacg
      841 gcgagataga aaaaattccg atgctgaaaa cgttcactgt atttaatgtt gagcagatcg
      901 acgggctgac actcacagaa gaagacaccg ccgagccggt aagcgagttt gatccgctgc
      961 cgcatgttga agcacttttt cagcgcaccg gcgcgaacat caccgagcgc ggccagcaag
     1021 cctttttccg tccggctaca gatgaaatct ggttgccgga gcgtcattta ttcaccgatg
     1081 ccgccaactt ttacgctacg gggcttcatg agcttgttca ctggacaggg gcaaaaagcc
     1141 gtttaaaccg tgaaaaatgc ggacggttcg gatcggaagg gtacgcattt gaagaactga
     1201 tcgcagagct tggaagtgct tttctgatgg ccgatttagg cattaccggc gacgttcagc
     1261 atgagagcta tatcgcttcc tggttaaagt cattgcgtga tgataaacgt tacatcttca
     1321 aagcggcggc ggcagcttca aaagcgcacc gctatttaat ggagtgctga ttaggttcag
     1381 accccgcgaa tcgcggggtt tgtaaaacgt cataaggatg tcaaaatccc acataaaagg
     1441 atgtgggatt tttccttttt ttaccgtaga actccgtcaa tattgagtcg ccttttactg
     1501 tttttttgtc tgatttttat gctaaagtaa ttaatgcctg tcacggtgca gacagactac
     1561 ggtctgtaca ggcttaaatg cactacatcc aatcattttt gttgaagcaa cgtcacgtta
     1621 tgttgcttcg gcaacgtagc gtgacttctg cttaaaggag ttaacgttat gactatgtat
     1681 caggatctgc cctctgtact gaatctgatt aactgtgaat caccatttcc atgtaatcag
     1741 gcttcttgtg ctcagggtat cgcggacaaa aactcgtttg tcgaatttat tgttacgcat
     1801 aaatcagcag gtaatttgca tgaatggaat ttgtcttacg ttgacaggtt caatcgtttg
     1861 attaaggttt tttaccacga tcacatgata ttacatgcac gtattaacat gaaaacaggt
     1921 attgtcaatc tcattgccta taccgtgttt actgataaga taagttcgct tgaagcagaa
     1981 tatcttgtcg aacaaatacg ccaacactta gatcatttct aactgattaa gtgcatgaaa
     2041 gggaaagcta atgctttccc tttattttta taagttatct ttcacttttt taaacaattt
     2101 tttcctttcc tgcttcattt catgcaattt ttcacgtaaa gcggcatatt gtttcagtat
     2161 tttatttctt tttatcagta aggtggtttc atctatagag ccattcaaat actggactct
     2221 taattgttta atgatattgt cagccaacgc tgtaatatta ataaacaaca taacgtgagg
     2281 tgaaattaat acattaatat cttgtgtttt atcgtgatat tcaacttgtt ctaatatctt
     2341 tttgaaaaag attatttgac ctgtgatgtt tctttcttcc tgatagattt tttcaaattt
     2401 atcttttaat tcattcaata cattgagtat taaaggggat tgtttttgtg ccagtgacgc
     2461 tatgaggtaa tgttcgttat ctctgaaatt tttaattttt gaggcagtga aaataatttc
     2521 taaatctttt atagttctta tcccgtcagt ggcgaattta tattttttct gttctttagc
     2581 cattgcgtga ttaaattgcg ctagtagcgt atcatcatta attctgaaat taattgttgt
     2641 ccgttccatc agatacctgc cttaacgctg ttagcaatta atttttctgt atctgcgatc
     2701 cgttggttgc aaagtatcaa tcccaatgga atgagtaaat ttgattcttt gataaacccg
     2761 tagtgtttgc ttaattcaag gagtagttgc tgatattttt tgttattttc ggcatgatac
     2821 attgcctgta ataaacgaca ttcttcctgt gttccccgct caatcgccca atcaaaaacg
     2881 gcattccaag aaatctcagt gagctgataa aaatttttcc ggcgttgttt ttctttgtga
     2941 ataactgcct tgaatttttt tctgaaatta ttgtaatctg cggctccctg ttttggatct
     3001 tcacatcgaa cgccctgcac cggacgttta tcaaacgtca gttcatataa tccgatatcc
     3061 ggtaaatatt cgtaatcctc tggtgtggct aatctgaaca tattcacctc aatagcaagt
     3121 tagtgatcac cctgtctgca ccatacgggg taatgtgaat gccatcatct gttctgatgt
     3181 ttctgtcatt cactgtctgc ataaagttat aacccagtac atcacgcata tcaaaaaaat
     3241 ctacactgtg ctcaatacat gcagctttga tgattgacct tgtgtaaagc aacatagact
     3301 catgctttgc gtttttaagt accggaggaa gtaaccagat aatattttta tttttattta
     3361 atagtgacat tataaaggta tctacacggt cttgataaag tatttcatca ttttcgttta
     3421 tcatatcatt gatacctaac acaatatata ttctgtcata gttgcttaaa tccattgttt
     3481 ctatgtagtc agtccagcta agaatgttat cggatttcag tcctgtgctt tctaaaaatt
     3541 tcgcatctac aggttcgatt tttgaaaaac ttgatgccag actgtaagtc agagaatcac
     3601 cgataaaaag tgattttgag aatgatgtgt ttgacataat catcaaaact aaaaaaatca
     3661 atatcttcat tattgtattg cctttttttt gtgattgatg ttagatagcc atctttgcac
     3721 ttactgataa gtaagtatta aacctgccgg aaaatcaata ggtgatgtat ggaaaatgtg
     3781 aacaaaccaa ataatgctat tgaagaaaag atagaaaact taaaaagtaa actcactgaa
     3841 ctagacgaaa aacgagaaaa gttaatcaca agaattgata aacttgagtc acagatgaac
     3901 gctgaaaaag cacaaaaaat tctcgatgat aagagacagg agcttgagaa tttactcgga
     3961 aaggaaaatt tagatctgct ttttggcagt aaaaagtagc aaaaaaaaag agcctgtaaa
     4021 ggctcttttt ttgcgtgtaa atagctgatt gcttgttggt ctacttgttg actcacttgt
     4081 tgttttgctg tcaacaaatg agtcaacaag ctaaaaatgt gcggatatac atagatccgc
     4141 atgacaggga tagatagtta atctatccct gtcaactgca ttgatttatc attctgataa
     4201 atcaacaaaa atgttgccgt taccggcaat gagggtaatg acctcctgaa cgtcggtcaa
     4261 aaccctcaag gtcaaaagag gcgcacaccg tcagtcgttc cacgactgac cacccccaaa
     4321 aagacgccgt ttttaacggc tcattttcgg tactgccgaa aattcaccga aaactggctt
     4381 ttttgagggt ggtcagtcgc gcggaatttt gcgataaagc cgcaaaatat ccttactcgt
     4441 gacggtgtgc gggggcgctg ccccccaaaa aggtcgcgct aggtcgcgct caattgcgtg
     4501 ggcgcaatta ccctttttgg ctccccccga aaccgtcatc atcgtcgctt ttggcgcgac
     4561 ggctgatgat gagttcgacg acacaagccg ctatacacac agcggcaagt tgtctcactc
     4621 attttttttc ttagcaattt tttcaaaatt gaagaaaaaa aaccgaacat caagttccgt
     4681 gtcgttgtcc agattgtgct cagtttttgt tgatttaatc gatcccttaa cttacattta
     4741 ttctattgta atctgatggc gcagggtgaa ttatggatca ggggctttat ggattcaggc
     4801 agtttggtta tgtgattgat aacttttcat ctgtattttt gtatcatcac tggttagtgc
     4861 tttttgtcat ttgggctatc tttgttttga tggtcagtat cattgtcaga agtttaaatc
     4921 atgttatttt catcggaatg tctgatgatg acagagaaga ttcaaggaat gtagaggtta
     4981 atggtaagcg tcaaaaacgt ggcgtgtttg catctatgca atatgacaaa ccttactttt
     5041 cgttattgct tttaaggcag gcaggttttt ttattaaaat actgctgatt tttattatag
     5101 cttttatgac tgcatttttt attgttactc tgatttctgc tttttttgat attgattatg
     5161 tgattacacc ttacaaagca caatattatc ttttaactaa aactaatatg tatggattgt
     5221 caattatttt agttggttcg cttgttggtt atattgttag tgcattctta taccattcat
     5281 ttattaaacc gtttttcgga gagatagatt taatctttaa tgaagaagcg atttcacggc
     5341 gcgaatcatc aaaaatgaga gatgataaac taaccgatat tcgaaatttt aattttaaag
     5401 acagtattaa ttataatcct gttgattact ttcatgaggc taaaagtaaa aaaagtattt
     5461 tcctggggat cgacgaaaac aacaagccaa tattaatccc taagttaaaa tgggatgaaa
     5521 caaatattca ggtgattggt aaaatgggga gtggtaaggg ggttctttct accgttgcgc
     5581 ttgttcagtg tgtggagtta tataacgata ttaatattat ttttgaccct aaaaatgatg
     5641 agtgggcata ccatgtattt aagcatttct ttaaagatga tttactctat attgatttaa
     5701 atcgggggca gttgccacag gttaatccat ttaaaggggc taattctgat gaaattaacg
     5761 aattgttagt tgccagtttt ggattgggtg aaaaaggaac tgatgcagat ttctacaaga
     5821 ctggtgacag aaaggtatgc cgtgatttat cacagcattt tacgcaaggt acagatttgc
     5881 gcggactgtt aagcatcgct ttaaatgaaa atttccgaaa atcatatgac cggacgggcg
     5941 aaaacttttt taatcttctt gaagaattgg gacaattaga ttctatcagt gctcatgatg
     6001 gcattgattt agtcgatata ctgaataacc aaaataaaaa gattatctat atcacaggtt
     6061 cgctgcgtga tgaggttgtt gttaaggcac aaaaaatgct ctttttacgg atggtgcaaa
     6121 tccttgaaaa aagaaacaga aataaagatg ttactcacgt aaatattatg cttgatgaaa
     6181 ttaagtatct tatttccaaa agtgctcttg aagcaatggg gacgctcaga gataagaagg
     6241 ccaatattct ttttacccat caatccagag gtgatttaga ggtttccacc aaagaaattg
     6301 acgggcaaac tgcaaggaaa gtgattgaag atagtgcagg gctacgctgg atttaccgga
     6361 cagataatta tgagagtgca aaatgggcga gtgattttac agcgggtggt ctggtagatg
     6421 tagagcgtcg taatctttct gttaatcagt ctaatgttga aatggcttca aaagaagcga
     6481 caatatttaa gcagaaagct aattatgttg atatttcagt tattcaaaat cttccgtcac
     6541 gttgcgggtt aatagtgggg gacggacaac tggctaggct ggcgtacagc agtccgatcc
     6601 ttgtcgaaaa aagtgataaa tgcgttactt catttgaaac acaagcgatt tcttcccgtg
     6661 agtttttagc cagtatcaga gaaacaaatg ataaaccgaa aacttcaagc gataaaaaag
     6721 tgaaaaataa cagaaataca aaacctgttg ataatccgca atccggcacg atggttaacc
     6781 gtgaacgagt aaacagtgct gtagatgcgg atagggtaga ttctgttatg gctgaattaa
     6841 ccatgccaga tgataatcac ggagataatt atcatgagca tagctgatta cggttcattg
     6901 agtaatcaaa agcgactgga acaacgccaa tttaatcaac ataagatatt aagttttttg
     6961 gcgcaggaac gcagcgttac tattgacagt ctgagccgtt tgtttgattt ttccgcaaac
     7021 caaaaaatct atttattact taagaacctg ataaataatg aattagttac ctatttcgag
     7081 gatggatttc ttggcagaac caaacggttt tatcatctga cagcacaagg tcaggctttt
     7141 gctgaacaag aacttggtat tacaccacgg ttcaacggat taagtcgccg tgctcatgcc
     7201 ccgtcagccc tgctgcatac actggaaatg cagaactaca cggcgttgct gatgaaagca
     7261 ggggcgaaag tccgctatct gcatctgccg gataaaatta tggattactg gtacggtggc
     7321 actgcggcag aagtcgaacg cacgtttaaa agccaaaaac gttaccgtga tatttttcgg
     7381 aactactgtc tgcggatgcg ccgtaatgac cccattatta ataccgtgat gtatatcctg
     7441 cctgattcag ctatgcggga taaagcggca gccctgtttt acagttttga tgaactgatg
     7501 attgaaggca ttctgactga tgtcagaacg tatacagggc gttttctgtt tgccacccga
     7561 gccgaatatg aagcctatct gacggcgttt ccgcaatccg gtgtcagagt cgagatgaaa
     7621 ctgccaaatg aggtgtggca acgctggcag cgacacgcag cacaggctca actgacaccg
     7681 gaagcgtggt taaccggtat tcttaacagg gaagtgccag ttgtgatcaa tgagccgatg
     7741 ccgtattcag gtgacggggt gctgattaac ctgactccga caaaggatga ttacaaattc
     7801 tggctggcga atgctgatgc ctgtcatacc agcctttcag catggtgtgc agggaagcct
     7861 gttcacttaa atttatagaa ccgtgcgcag aaacaggttt tgactgatta ccggcgataa
     7921 tagttaatca ggtaatcagc caattcttca tcgtcgcaat aaaagtaaca ggttgggatc
     7981 tgtaatatag acgctatttt ttgcattagc tgataagagg ggacactgta gccgttttca
     8041 tactggctga ttcgtgaact cgctgtgctt tcatctatgc ctgcttttat ggccagcagc
     8101 tcctgtgtgt aatgtctttt ttttctggcg gtttttagtc tttcggggat catggcaaac
     8161 tcctttggtg aagtctgcca aaaaaaaaaa tttaatttat ttaatgatat taagatttct
     8221 tgtttttcag ttttaatgat tcaggggggt ttatcgggcg tgaaaaaatc tcagcctctt
     8281 tgtaccagta ttcttttttt tcagggattt cttctctttc tgccttgatt acataggcaa
     8341 tttcttctgt tgtgatcccc agtaatcttg cgaggtgtgc gcattctgcg ggagagacat
     8401 agccttttcc ctgtttccat tgtgaaattt ttatcggtgg agcgtccaga tattgggcta
     8461 tttttcggta actatcacaa atggttagct tttttgcttc ttctatgtac tcaaaaaaat
     8521 tttttttcat aaattattgt ctttggcgtt agtgtactgt attttatata taatacagta
     8581 tttggtaaca atgttaaccc tatactactt ttcacgcagc ttatgggtac ggattgtgat
     8641 cacaaacaat acactgaaac gtaagttttt aaataccctt ctctttttcg gcgttttgtc
     8701 cggttgcgtt atgctttatc agcattattt cgttgtcaat tttactaaaa gtatgccgtt
     8761 aggagtgtac ttcaaaagtt atccagcatc ttatacaaaa aatgatacgg ttttggtttg
     8821 tctcgatgat gagatagcaa gatggtctgt tgatcatcac atcattgctg atggtttagg
     8881 ttgccggcat tcagcaccgt tactcaaaaa aatcgtagca actgaggggg acagggtaac
     8941 tgtgacccat aaaggcattg ttgttaatga tgttttagtc ccgaatactg cgccaattgc
     9001 caggaaaatt aagcagtgga acattatcga tagggaaatt ctattaaaat caacggagta
     9061 tatcgttgtc gccaatcaaa ataatctgtc ttttgacagt cgttattttg gtgtagtaac
     9121 agaccggaat attaccgcaa aaatcagacc tttttattta tttgactgat ttttaaggtg
     9181 aaaatttttt atctgtgggg ctgatagaac cgccttatgc ggtagctatc acctgaataa
     9241 aggagttctc ttgattgata tgccgagtgt gtctgcatgt gcgccggaga tagccgcaga
     9301 tacgttacag aaaattatta tggttgaaag tggcggtaat ccttttgccg ttaatgtcaa
     9361 taaactgtcc gccggaagcc agcctaaacc gaaaaacgtg gctgatgccg ttgcagcgac
     9421 acaatactgg atagcaaaag gctattctgt tgatgtgggt ttaatgcagg taaatagccg
     9481 caattttaaa atgttgggta ttactgatac tgatttaggc tctgtttttg aaccctgcaa
     9541 taatgtgaag tacggagcaa caattttact ttctgcatgg aacatgactt catccaaaga
     9601 acaccagaac gaccggctga tgaaatcatt gagtatttac aatacgggta atgacgttaa
     9661 cggatttaaa aatggttacg tcagtaagta tgtgggaaga aacatttccg gttcactggc
     9721 aaaaacggtt gtcactcctt ataacgcaga ttccagtgta gggtttaatg cagactcttt
     9781 ttacggggat gatttatgaa tacgggtgat gataaaaaaa tcagtgacct tgccaaaatg
     9841 ctttggcggg agttcgatat tattgcgcct tatctcaggg atgaaaccac tattgaaatc
     9901 atgctcaatc ctgacggtaa aatatgggtt gaacagatcg gtaagccaat gttcagtatt
     9961 ggcgaaatgt cgttatataa cgctcaatca ttatttgcca ccattgcaca cagcatgggg
    10021 aaaacaatag ataatcgcca cccttgcctt gagggaacgt tgcttattaa tgatgcgcgt
    10081 tttgaggggt tctatccccc tgtttcaagt gcgcccacct ttgctatccg taaaaaacct
    10141 aaaaaaatat tctctcttga tgattttaaa ttaaccgaaa atcagaaatc gacgatggtt
    10201 acatgggtga aagaacgtaa aaatatttta gtcgtcggcg gaaccagtag cggtaaaaca
    10261 tctttttcta atgcctttat tgacctgatg gcacaattta cacctgatga tcgtatcgtc
    10321 attcttgaaa cgctggacga aatccagtgc cgcgcaaaaa attattcaaa actgattgaa
    10381 acaatggatg tgacgatgaa tcagttactg cgcggtgtga tgcgttaccg ccctgaccgt
    10441 attattgttg gtgaagttgt tgatgcagcg gcgttatcta tgctgaaagc atggaataca
    10501 gggcatgacg gagggttatg taccattcat gccgacagtg cccttgaggg gtttgaccgc
    10561 ctttacgatc tgattgaaga aagcgggatt aatatgtcag aaagggtgaa ccggctgatt
    10621 ggacgggcga ttgacggcgt tgttttcctg aaacgggaac aaggtgttcg ggtagtcaaa
    10681 gaagtcgcaa atgtgacaga atttaacggc agtgaatttg tgcttgatta tgttaattaa
    10741 ggaaaaacta tgttagagaa atattactat agccagtcga gactgaccca gcaactgata
    10801 gtgttaggtg cattgctact ggtctgtatg ttgttaagca gtcatgcaat ggcaggtcag
    10861 acgcaaggtt taccttggga aagtccgctt gataaaatca aaaacagcat aaccggcccc
    10921 gtagcgggag cgatttcctt tctcgggatt tgcgttgcgg gaatgatgct gatttggggc
    10981 ggtgaaatgt ctgatttcac caagcgtatc gtttatgtgg ttctggttat ctctttaatt
    11041 ttaggggcaa gtgtggttat caacatgtgg cagggtaacg gtgcattgat ccctctgtct
    11101 atggtgtaaa cgccatgaaa acacaagagc cgctggttag ttttattatt caccgctcgt
    11161 taaatcgtcc tgatttagtc tttgggtgtg aacgtaaacc gttatattgc ttgggcttaa
    11221 ttgcagccgt tatgattttt tcttcttata acctctatat tgcgggggcg ggtcttgttg
    11281 ttttctgcgt gggggtttac ctgttgcgac gtatggcgaa agccgatcct ttcatgtcgc
    11341 tgatttttca gcgggctatc cgatatcgtt attattaccc tgcaaggagc acaccgtttg
    11401 caactggtgc aaaattcaga aggaaaaaac aatgaagtta tataaaaaac aatacaatac
    11461 atcactttct tttgctgact tactgaattt tggcgtgatg attactccca acttaatgtt
    11521 gggtaaagat ggttcactga ctgccggatt agtttatacc tgttgggatt atgaaaattc
    11581 tgataattct gaattaaatg acctggttaa tgcacttaat gcagcctatc tccggttggg
    11641 tacaggtatc acattgcatt ttacggtaat aaggagtgaa acctcagaat atccgcagcc
    11701 ggaaaaaagt cattttacgt cattactgaa taaattaatt gatgaagaac gccggatcaa
    11761 atgggaaagc gcaggggcgc atttttcgag tgtgctttca ttttcaatta cttatttacc
    11821 tgaaagcatg tcaaaaagtc ggttaagtga tttctttgtt accgacgaat ccggcactaa
    11881 aaaatcaaaa tcattaacag ataaacacat tgaatacttt gaaagcgtta tttcagaact
    11941 cagcggacaa ttaagcggaa cgtttactct gcaccggctt ggggtacgcc atgataacgc
    12001 tacaggtgtt gtttataatg atttagtcca atatttcaat cattgtatca gtggtgataa
    12061 ttatccggtc attcatccgg ataatcagtt tcttgatgct gttttgtcta cggatgattt
    12121 ttatactgag cctcgcctta aaattggtaa taaatatatc agtgtgcttt gcattgatgc
    12181 ttatccggca agttcagtga tggggatgct gcaatcgtta tcaaatttac cttgtgagta
    12241 tcgctggacg acccgcgcca tatttcttga tccgatagat gcggataagc aaattgaaaa
    12301 ataccgtaaa agttgggggc agaaagttcg cggatttgtc gatcaactta tgggtaaaca
    12361 cagcgataat attaattatg atgcagccac gatgaaagag gatgcacaga ttgctaaagg
    12421 tgaaaataac tcaaatacgg ttcgctatct gtatcttacg cccacaatag tgattatgga
    12481 tgaagatatt gaccgtttgg atgaaacgac aaatcttatc cgtaccacga ttaaaaatgt
    12541 cgtcaatttt aatgcaagaa ttgagacagt taatgcaatg gatgcctacc ttggcagtct
    12601 gccgtctcat acctatgaga atgtgagacg ccccctttta cataccggaa atatgacgca
    12661 tatagtgccc tgttccacgt tgtggacggg cgaagaaaca tcaccctgcc cgttctttcc
    12721 gccggacagt ccgccgctga tgaaggtcag tacaacgggt aactccgagt ttaatcttaa
    12781 tttgcatgag gacgatgtag gacacggcat tatcggcggt aaaacaggtg cagggaaatc
    12841 atcattagtc acattaattt cttctcaata tgaccggtat cctgattctc aggtatttac
    12901 ctttgataag ggacgttctg caaaagtgtt ctgcaaacta tcgggaggaa agtattacga
    12961 tattatgacg ggcgagcatt ctcttaactt tgcaccgctg gcgcgtatag atgaaccgag
    13021 tgagtttata tgggcgtttg agtggttaca ggatattgcc gaaattaacg gcgtaaagct
    13081 ggattctgaa aaagttaaaa aactgaatga agccctgaaa attgtctcaa gaatggataa
    13141 taaggacggc cagtaccgca acattgattc actgattaca aaattgcaag accgcgaatt
    13201 gaaagatttg ttcagtcagt acggctccgg cggggcatac ggtgaagtgc ttaatcagcc
    13261 acaagaacaa attacactca gtaactttac cgtttttgag tatggagaat tactggacag
    13321 gggcaataaa atcaaactgc cggtactttt ttatctctgc cacctgattg agcgacaact
    13381 cgacggaaga ccgacactgg ttaatattga cgaggcatgg aagtttttag atgaacctgt
    13441 tgcgggtaaa cgccttttac aatggctgcg tgaatggcgt aaaagcaatg ctgccgtggt
    13501 tatttccacc cagaacctgc acattatcga aaaagccttt ccgctggtat tttcagaaat
    13561 cgctatggct tgcccgacaa aactgtttct tagtaacccc gccgccgagg aagaagtttc
    13621 gatcaatgct tataaaattc ttggctgcaa agccgctgaa atccgcagaa tccgtcattt
    13681 aacgccgaag cgtgagtatt ttgtgaaaaa aggtgatttt cgccggacat tcagcctcga
    13741 tatggttgag ggtgatatcg gacttgctac cgttgccgca agctctaaaa aggatttaaa
    13801 agagatagat aaattagatt ttgaacattc cagtgaagaa gaattactgc accagtggct
    13861 tgattttaaa ggtgttgata gtggctatgt gcagtatctg acagacagac tgaaatcaag
    13921 gggtgaaata tgaaaaagat attaattgca ggtgtgtttg caataagcac atttacaacg
    13981 ctgaatagct ttgcgtggca tggggttgct actgaaggca cgcaatggct gaataatctt
    14041 caactggtaa aacaggttga agagcaaatg agaaccgtta aaaatcaaat tcaggattta
    14101 caacgattgc cctcagatgt tctgaatatg ggatcaaaca agttaaaggt tcttgagacg
    14161 tttaatgatt taaagcgaat ttatcaggaa gggcaaaata tagcgcaggc agggcgggac
    14221 gttgctaaat attataagga tatgggcaat attgatattg ccgatgccct gaaaaacggg
    14281 aattacccgc agttattcaa tcagtggagc caccagaacc acgatacggt aaaaggtatt
    14341 ctggaacaga ataaattatc aatggactgg tttaatgacc gacagggcga ggttgcagga
    14401 tataacagta tgctcaattc tgctgatggt acagtcagtg cattacaggc agcgggtaaa
    14461 attgctaatg ctcaactgga tagtctcagc cagttggggc aattgcagat ggcgcaaaat
    14521 aacctgttag cctctcaggc ggcagttcag caaagcgaaa aagatgcgga gagagccgat
    14581 acgatccggc gttcagaaat gaatgtgatc ataaattctg ataacaacac cgctgctgat
    14641 tttctaaaga gggactaaat atgaaactga ttaccacagg actttctttc ttcctgataa
    14701 ttaccgttgt ttctacagga tatttatgga aacaaaataa agagttgcat tatcagatta
    14761 atgagctatc taccgttgtt gctgaacaac gtgttgcagt acaaggttgc cttaaagaaa
    14821 aaacagatac gcaacataga ggtaaagcta attttgttat tccagatgat tcaggtaatg
    14881 cggaagattg gttaaaacga taactacgat aaggatgtgc catgaaaaag attattttcc
    14941 ttttctgtgt attgctaatg ccatttttaa cacatttagc atatgcggat gatgtaagtg
    15001 gattaactgg tgaatggaag tcgccggaag aagtccgccg tcttattgat gaaagtagaa
    15061 gagaaacagc tttaataaat cagtacacta atgagtgtgc aaagggtaat aatcaaagtt
    15121 gtattcaatt ggaaactata aagtcaaaaa acagcaaaat taatttagat gcaaattttg
    15181 tcaaaacttt tagcgattca tttcaacaag aaataaaaaa gtggctaccg cctttgcaaa
    15241 aagcggccaa atatttactt tttacacttg ggattatcgc actggtctta aaaatggttc
    15301 cactggttct aaagggtgct gatttagggg agataataaa agaacttata atttttgttt
    15361 taattattgg tatctggctg gcatttataa taaacgctaa agagtggact gatgcaatca
    15421 taaatagctt tatgaaacta gctcaattag ctaatcaaac atctatgcaa gccacgcctg
    15481 ttggaatatt aaaacaagga tttattgttg ttggaaaggt gtttactgac ccgataaacc
    15541 ctataacgtt attaactcaa gttatttgtg cgttaattat aatgatcatt tatgcgaaaa
    15601 ttgcatttta tttgctgaaa gtcatgcttg agacgtacat tgtttcttat ggaggcatta
    15661 ttctgttggg gtttggtggg atagctttca ccagtgacta tgcaaaacgc tattttacct
    15721 acgttatatc atgcggcatt aaattattta tgacattact gattatcggt tttggcggta
    15781 attttattgc ctcattcctg actctcaatt ttactgaatt tgcaaattgc gtcgcaattg
    15841 ttgctgttgt tgtcatgctt atgatgctgg ctgaaggaat acccgacatg gcacagtcta
    15901 tggtcactgg tgccagctta ggcaatagca atatgaatat cggcggctct cttgcaacaa
    15961 tggccgctgc cgccactgca tttaccgctg cctgttatgc cggagccgcc gcctttaaag
    16021 cggcaggggc ggccaatgca gcaggaggag gcggagccgc tacaggtgga ctttccggcg
    16081 gtgatttagc gaatgcgtta agcaaaggcg gcggctctgg tgttgccggt gggggcggtt
    16141 ccggcggcag tagttcactg cctaacgggg ggaaatccgg tgctcagtta gtgaaagagg
    16201 gaaaagtaca atcgcctaat aaaaatacgg gtaacacagc aacgggtact gaatcaggaa
    16261 aaccacaaca aagcagaacg ggagcagccc tgaaagctgt cgctaaatcc gttggtgagg
    16321 gaatactcaa taaagcggca ggaagcagag gctccacggc agcaaacatt acccgtgcag
    16381 cgttaaatca tgcggcacaa agtcaacagt ccacagaaag ccctcgtaaa cctattgcca
    16441 gtccgtatgc aaaaagcacc ggaaataata gtagcggaac cagtaaaatg cctaacaagg
    16501 gaaataatga tacaggggaa aatcaatgag tgatgataaa ttcaaaaaat cgtccggctg
    16561 gaacagtttt ttaggcaaga ctaaagaaca agttacgttc taccgatgga cgactatcct
    16621 ttgcgctgtc gcggctatta tctctatttc tggctgtatt tatttctctt ctcaggtgaa
    16681 atatgtgccc tttgttgttg aagtcaacaa agagtacgcg ccgttgcagg ttcatcagct
    16741 agaatcttta gggcaaagca aagatgcggt tacacgttcg caactggcaa cgattatcaa
    16801 aaatatgcgg gtagtctatg ccggagataa agaagcgcaa ttagatgcta ttaaatcagt
    16861 ctattatttc atcaaaacca actcgcaacc ttacaaatat gttcaggaga tgttctctgt
    16921 tgatgacccg atgaatcaga aatttttaaa tcaggtggaa ataaaagcca ttcttccttt
    16981 aagtaaagat acatggaggg ctgaatgggt agaaaagaaa gctatgcctg atggtaaaaa
    17041 tgttctgtca cgaaactatt cagcggttat tcaggttgag tatgcagata ctatttctgc
    17101 tgaaatgatt atcaataacc ctatcgggtt atatcttaaa aatatgcaaa ttacagaaga
    17161 atataaatag gatataacgt tatgaaaaaa acaattttat ttacctcatt gctgatttca
    17221 ggcgttgcat tagctgatcc tgttgtgcct tctgtcagta atatagaaag gattaataca
    17281 ggtgcaacct ctcaaccaac aacgccacag caggctatgc catcttcaat gctcttaggt
    17341 ggtaaagact tacctttaag ccgaaaagag caacaggcga ttaaaacagc aaatcaatgg
    17401 gttaacggga aacagtatat ttccaatggc ggtcaggagg tagtgtacac atacggagca
    17461 ggtcaggcgg ccattattgc cacaccgcta aaactcagtg tttttgagct tgaatccggc
    17521 gaacgtattg ttaatgaggg tattcagtta ggtgattctg ttcgttggca cgctaccccc
    17581 gtaaaacagg ggaatcagac gaatgttatt ataaaaccaa ctgacacagg actatcaacg
    17641 gatttagttg tcgtcacaga ccgccgtact tatcacatta agttaatttc aaacagtaaa
    17701 aactatactc cattagtcaa attcagttat ccggaagatg aaaaccaaaa agcgtggaat
    17761 gcgtactatc aaaattcagg tgcagataat agcagtatct cacttgccgg aaataaaacg
    17821 ggacttgccc ctgtaaattt tgattatacc attaaaggcg ataataaaat gaaaccgttg
    17881 cgggtttacg acaatggttc tcaggtgttt attcaaatgg atggaaaact acaggaaact
    17941 cccgcattat ttgtcattaa tggctcagga aaacagcaat tagttaatta tcgttatgta
    18001 gataatacct ttgttgttga ccgcttgttt aacaaagctg ttctgacact tgatgttggc
    18061 ggtgatcagg aaaaagttac catcacaaag gggtaaacga tgaaatacaa attattcttt
    18121 gcctttgtat gtatggtatt agcagggtgt gttagtaagc ctaatatctc atcgtatgat
    18181 ggtacacagg gaacgatagg gaaaaacagc gttcaaaaaa tgttatatgg cgttgatgtt
    18241 attttttcta aacttcattc aaaaaatact attttttata ttgaggattc acattctgat
    18301 atagcaaatg cttttattga aaatataaag cgaaaaggtt ttattgttat cgttacaaat
    18361 aaagaagata aaataaacta taaaaaaata aatatgggca tgattgtgaa gaaaataacg
    18421 ccggatattt attctctttc aattattacg gataaataca gaattaacca accttatgac
    18481 tatcaattaa ataaaattgg tgaggtttcc attcaaaata aaaccgagga tgttaatcat
    18541 ggctaacccc tcacaaaata aaaagctcac taaaaaacaa aaattattaa tgacgatagg
    18601 atttgctgct gtcctcatta tttttgttgt ttttatttct attatgagtt tagggactaa
    18661 taccgatagt caaacgcaaa gttacgaaga tgccaaggat aaatcaggtg atcctgctga
    18721 cccatcctat gaggctaatc tgtatcgttc ccgattcaga gaaaatactg atttacaaac
    18781 accccctgca acaccagata aagccccatc tgcaactgga acaatacaaa cagcaaatgt
    18841 gagtcagccg caatctaata gcacacagac tcaatcacag gaacgtgatc aatttgcgga
    18901 aaatgtttta aggatgaagc aacaagccta tatggaggca ctaaacagta aaacaacggt
    18961 gcgggttgat gcgctcagtg ataataacag tccggagcgt ggtagttcag ccccagacta
    19021 tgcctcaatt gcagagcaac tcgccgccgc ctcgaaagag ggaaacggag aattgtatgc
    19081 caacatgcag caaaacaaag aaaaatttgt gaatacagaa cgtacctttg gctactcaac
    19141 tcagacaaga gaagccgcgt tgtctcagac agaaatcaag gccggaatga ttttaccggc
    19201 ggtacttgtt acagaaatca attctgattt accaggacta attaccgcac agataaccga
    19261 agatgtgcgt gacagtttga caggcagaaa aatactgatc ccaagaggtt caaaactcat
    19321 cggctcttat gattcacaag tagctatggg gcaagagcgc gtgttagtcg tctggaacag
    19381 agtccagttc ccagacactt caacacttgc ccttggtaat atggggggaa cagatggcat
    19441 ggggcaatcc ggctttaacg atgaggttaa caatcattat ttacgcatct ttggaaatgc
    19501 aacgttactt gcgattattg gtgcagggtt ccagctttct caacctgata ataatagtaa
    19561 taacggcaac aatggtatga cggcaagaga gcagatgatt gctgaaatag gtagacagtg
    19621 gtctaccgtt ggtacagaag ttgtgcgccg aaatctgaat attcagccaa cgttacacat
    19681 cagagcgggt tataaattta atgtcttggt aaataaagac atcatattgc ctgaatacca
    19741 gccaaaccat taacctaggt aataaggagc aaaatatggc tagcagaggc gtaaataaag
    19801 tcattcttat tggtaattta gggcaagatc ctgaaatccg ctatatgcct aatggtggtg
    19861 cggtagcgaa tctatccctt gcaacatctg aaacgtggcg ggacaagcaa actaacgaga
    19921 tgcgggaaaa aaccgaatgg catcgggtgg tgattttcgg caaactagcc gagattgccg
    19981 gagaatacct gaaaaaaggg tcacaagtgt atattgaggg ttctttgcaa acccgtaaat
    20041 ggcaagatca aagcggtcaa gaccgttatt caacagagat tgttgttaat atcggcgggt
    20101 caatgcaaat gttagggggg cgaaatgggg atgctccagc aacagatcaa agtggacagg
    20161 gacaaactca agaatcccca aaattcagcg gtggcgatgc tcctgcgcca gctaaacaga
    20221 ccaatgaacc cccacttgat ttttctgatg atatcccgtt ctgaatgata taaagtgatt
    20281 atatatgcaa tcctgagtgt agcggtagtt tttaaaacaa gaggaataag tatgcaaata
    20341 gcaaaattaa cgtgtttgat aatatttggc ctttctgctc tgactgcaac tgctgctgag
    20401 tctgatacgg aaaataataa tcaatgcgta taccaagggc agtcatacgg tataggctct
    20461 cctattaaca ttgatggtca ctcatatatc tgtgtcaaaa aagccaataa aatgatgtgg
    20521 ctaccggcta ttgatgcaca acgatatctt taatagggat tattagatta tatgatttta
    20581 tttttcgagc gttcaaagcc attaactcac aaaatcgata acattcttct ttctgaaata
    20641 aagaaaagag agccattgaa atatcatagt tttcaactga ctaattttat ttcaggggtg
    20701 ctgtttttgt gttgtttgtg tagttttgtt tcttatattg ttttttctgt tttcttacaa
    20761 aattctggtg ttgaaataga tccatctgta acaaaaatat ttgccaaggt tatagttggg
    20821 ttttttttat caggatttgc ttgttggttt ttgcgaacat atttatatac tgagcttgaa
    20881 caccagataa tgaagatttg gtacaggcaa gccagtagtt aaacaattat aaccaattat
    20941 ttaattgggg gttatcaact ggcgcaaata gcaaatctgt aacagataac agcgcgttta
    21001 agggggatta gtggatcata agttacagct taaagagctt ctgttaatgc acaatttgac
    21061 tcagcgggaa gccgccgcat tgatctcttc tcagtccttg cgtccctgtt ctgtcagggc
    21121 tatcaagtcg tggcttaccg atgtatctaa ccctagttcg cgttcgtgtc ccgattgggt
    21181 tgttccacta ttgaaaatag ctctagaaac aagggattct acgccagaat cgccttaaca
    21241 gggggctgga gtgagtcata ataatttagg ttattactaa taattaagcc gtgtaaaatc
    21301 tgagggatta cctaccctac cagcccgatt ttccctcaga ttttgcgtag cgatgcctca
    21361 aaatctgata aagctacagt tttccgattt actatcactt tatctttctg cagcgcatcg
    21421 aactgcggat ttttgctatc actttttcaa tccggaagcg accggccaaa caaaaaatga
    21481 tagcaaaaat agtaaaaggt gatcagctga ccaaaaatat ctgctatcat ttttgtgttg
    21541 gccagttcgc cggcaccatt caaaatgata gtattccggc gtgaaagcaa gactggcctc
    21601 aatgtttagc catttgaggg gtatgtatgg ggacattaac agtcaggccg cagccggaac
    21661 atgaagatgc tctggctgct gtaggtgcat tgttgcagga aaaacgagcc tcacagacgt
    21721 tgctcaaatc actgatggcc tacgagccac actgtaaaga gatcgcccaa ctgaaagccg
    21781 cactgcacaa ggccgaaaaa gaacgcgata tgtataaaga taagatcgag cgttttaaag
    21841 ctgcccagct tgcgttattt gaataaaacg attagatgta gtaacatata aacatagagt
    21901 gacgaacaga aggaggtgcg ccatgttgac gacctttttt accagcagag aatttaacca
    21961 agagataggc aaggccaaga aagccgcttg tcagggggct gtgttcatta cggacagagg
    22021 taaggctaca catgttttgc tgtctattga tgagtatgaa cagatatcag gactgaatga
    22081 tgagaatatt gttgacgcat tatctgtccc cggtctgtca gaaattgact ttgatacttc
    22141 gcggttaagc atttttccgc ctgacaggga cattttctga tgtttatcct tgataccaat
    22201 gtcatttctg aactacggaa agccggagac ggaaaggccg acgcacaagt tatgcgttgg
    22261 ctttcatctg taaattcacg acaactttat ctttccgtga ttacggttct tgaactggaa
    22321 cgggggattt tgcgcgttga acgccgtgat accactcagg ggaagatgct gcgccgctgg
    22381 atggacggcc atgttctgcc gctttttgca aaccgtatct taccggttga tatggctgta
    22441 gtgcgtcagt gtgcccgtct gcacgttcct gatcccaagc ctgaaagtga tacacttatt
    22501 gcagcaacgg ctcttgtgca tggctatatt gtcgttacac gcaatacgaa agatttttgt
    22561 tctacggggg tgaatatcat caatccgtgg gaagataacg gaaactgagg atcttatctc
    22621 ttttaagatc ctgaaattga tcctgatgaa attaagtgtt agatttcggg gataagattt
    22681 attaacttct ggttagttgc gccataaagc agcagggaac tggttctgag gttttaccgg
    22741 agccagaaaa gcgaaaaccc cgataatctc tttagtttgg cgaccggaga agattagcgg
    22801 ggtatccatc atatactgtt agaagattta ttgccttctg acagggagta tagcgacatg
    22861 cctcatctct tgcaagtctc agtatgtgct ctttctgcgc aatatatgcg cagaatacag
    22921 tgatcgatag tcataatcag gcacaagaac agcgttcacg tggcattgag tggcggaata
    22981 gttatgtcac aaatgctaat cctgtgtact ccgcgcctaa agaatgtgcc agtccgccgc
    23041 gcattatcac cgctttacgt aaggcggctt tgacgtccaa cccagccaga caccctatat
    23101 ggcgtacagc ggatcgtttt catgccatta atcatcaacg gttgcctaaa gaacgtgcaa
    23161 tgaatgagca ccgcgcccgt gcggtaaatg ccatttgtgc gtgtattgct gaccgtctca
    23221 atatcgttac cggcaaagtg tttatgacac tggcgcaaat ttccgacagt tgtggcctga
    23281 ccacctacaa taaggatgga acgccctgct acagtcgcgc cagtcgcgcc attaacgaac
    23341 atcttgaagc tatcggcgca atccattgtg atcgcgtatg ggacgaaaca accggctcat
    23401 ggattcctaa cctgatatgg gtatcagaac tgtttttcac gttgataggc tacgagtacg
    23461 ggaaatatga ggcggcacaa cagcaacaac tggcatggga aaacaaggga ctgaaagaaa
    23521 aaggggaacc ggctatttca ttaaccgaag cccgcagacg ggcaaaggtt aagcacattc
    23581 agaccgcatt tgaagtccga gccaaaaaac gcgcgtttaa aacacagtta cgacaggcca
    23641 gaaaactggc cgctatggaa aaacagaaag cgcaggctaa aatccttaac gatctcgtca
    23701 aactctactc acaggacgaa ctggccgcta tggggcatgt tgaactgaaa agacaggttg
    23761 aacatcgcta tgcggccatg agaaaactgg ctaccgcccc gccacattaa aacattcctg
    23821 agcaattcaa ctatccggcc atgtacgccg gaggctttat cctgcctgat atactttttt
    23881 gtgtaaaaaa catccacttt tttctgtctg atccgtcatc gaccgtcgtt tttcggcatc
    23941 atgattgtat ggccgcaaca tacccacaat taaatgcaaa cgtaaataaa ggaatagatg
    24001 caaccataag aaatagatgc aaaatcactg tcttacttct tttaatcaca gaaaaagaaa
    24061 taataacgtg ctaacgcact gttaataacg cccgcccttg cagcggccaa aaggccgcgc
    24121 cggttcggtt agtcgctccg ctcctgagtt agcacccgca agcgggcaaa ttgctgaaca
    24181 tttctttcgt ctccgaccat ccggcaatct caccgcttta aattccgtgt aattggttcg
    24241 cttcgctcac agtctggcag gaaaaggggc tgacttacgc ttcacaccgc atcaaaaacg
    24301 tcacgtaagc cacatagacg acttttttta aagaaattca tagaacggga aggactaaaa
    24361 aatagaattg cgtacagcag cactgaggag gattttaaac atagaactta aaaaacccgt
    24421 aacgctcgcc gcaggacgtg gccgagcgta gcgagttaac gaccgaggaa gcggaatttc
    24481 accgatgcga cagaaagcac ttacacaccg tagcaacgtt cagcctaccg cctctcaccg
    24541 ttcgttgctc aacagcgacc ccgacgacaa aaaccagttt tgcgcgtctc tcgctgttag
    24601 gtggcagtta cttttctatc caatatttgc ccaaaaaagc aaacaggaac atcatcgcta
    24661 tcggagtcac cacaaatatt ttttcggctc ctgagagtga aaaaatgata gcaataaccc
    24721 cgaacattgc cacaaatccg atcactgcca atctcgcgta accaccacaa aaattagcaa
    24781 gttttccaat gaattttttc aatatagccc ccttgcaatt aacgaaaaag ttaaagtgat
    24841 aaatctatta aaattgaaat tgaaattgaa attgaaattg aaattgaaat tatcatccaa
    24901 acgatagcgg tgacaaaatt gttttggggg ttaaatatca ccacaaccta aagggcagca
    24961 attaggatct aaaccgtgtg aacaataacc atcttcttga ttttgtcgaa tagcttcggt
    25021 tatttcctct ggtgatatat aatcaaattc agctcttgcc aattggatta cttttctttt
    25081 atcctcttga gttaattcac ttaaataacc atcaattgct gtgctcaagt tgcgttggta
    25141 catttcatag acacacccgc aacgagattg ttctgttttt gataactcac tgaatatatt
    25201 acgatatttg ttaattattt cataatcgtg atattcacaa attaagactt ttttaccatc
    25261 aaaaaccgtg gttaaaccgt gtcttgatat gttattaggt agctcgctta tatcaatttc
    25321 ggcatcatca gggcattcat taagcgcatc tttaagttct ctaactgttt tgaatttatg
    25381 ttcaagcatt gtagttacct cattatctct attaaaaact tagccttatc gctaggtgat
    25441 agtgattcaa aggcaagcag cgaagcccgt aaaatgttaa tacgtttctt ccctagtccg
    25501 ttagtcagcc ggtctaaacg ttctaacgta tcttcatcca tacgaaaacc taccatgata
    25561 gattctgctt tttttgtcgg ctttttatcc ccttgggcga taaaatcatt aaccgtcttg
    25621 ctttctgacg gttcaattat tggcgcgtgt ttttttaatt tatttatatc cataatccac
    25681 ctcaatgcaa agctaatcat tgattaatca atgattttca attgttttgt tttcttagct
    25741 atcctgaaca gaatcaatga gttcagcgaa taaaagctct aattgtgctt tggctgatcc
    25801 tacattttta cctttaagct catgtactcc caacccctca tttatggctt tttcaaaagc
    25861 ctttaagttt gatatacggg ttttgaatgg ggatagaagc aggggatcat cgttaagata
    25921 ttgtgtgatt tttactgcat cattattaaa tggtgaagta gggcagcgat taagtaaagc
    25981 aaaggctttt agctttgtgt tttccttttt agcttcgttc acaatggatg ataatttatt
    26041 caatgtgaca acttctaaca tagatgttgg gcttacagga gctataaata catctgcaac
    26101 aagtaatgca ctacgaagct cgacgctatc atgtccggca gtgtctacca atattacatc
    26161 cgtaacgccg tgcaatttgt taatctcttt atgtgtattg cttccgtaac aagtcataat
    26221 tgggatatca ggaacaggct gttctcgtcg taaactttgc catgtgttca aatcttcgtt
    26281 tttgtctgtt cgcactaatg ctacagacgc cgttttttgt tgcaacatta ctgctgagtt
    26341 agccgtaatt gtggtttttc ctactccacc tttatctgag ccaaaaacta taatcatttt
    26401 ccttacctct cagtgagatt catcaaggat taatcaatgg ctatcaataa tgattaatcg
    26461 ttagatatca aatggtgata atctatgatt aatcatatca agataatcat agattatcaa
    26521 taatgattaa tcaaaagaca gcaatataag ttaatctttg attaatcatt tgcgtaattc
    26581 aacttatcaa gcgttgggcg aaaaaaagcg atgaagttta attttgttaa aatgtttctt
    26641 aattgtttct attttaacaa aaaacaaaca atggtatttt gactggattt ctgacagaag
    26701 agttcctgtt ttagcgggta gggcggttgt gtgacagggt aacagtgatt tttggtgcta
    26761 aagtcctgaa tttaacataa tgactcttac gcgcccctcg tttgtagcac caatattaaa
    26821 atgtcactcc ggtgc
//
