LOCUS       NZ_OW849494            12879 bp    DNA     circular CON 03-SEP-2023
DEFINITION  Serratia marcescens isolate 0 plasmid P3, complete sequence.
ACCESSION   NZ_OW849494
VERSION     NZ_OW849494.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA7962735
            Assembly: GCF_905232465.2
KEYWORDS    RefSeq.
SOURCE      Serratia marcescens
  ORGANISM  Serratia marcescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Serratia.
REFERENCE   1
  AUTHORS   Alioto,T., Alioto,T. and Gomez Garrido,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAY-2022) CNAG-CRG, CNAG, Spain
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/02/2023 08:00:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,620
            CDSs (total)                      :: 5,490
            Genes (coding)                    :: 5,399
            CDSs (with protein)               :: 5,399
            Genes (RNA)                       :: 130
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 18
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 32 of 92
            Pseudo Genes (incomplete)         :: 62 of 92
            Pseudo Genes (internal stop)      :: 13 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OW849494.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12879
                     /organism="Serratia marcescens"
                     /mol_type="genomic DNA"
                     /isolate="0"
                     /isolation_source="Complejo Asistencial Universitario de
                     Salamanca (Salamanca)"
                     /host="Homo sapiens"
                     /db_xref="taxon:615"
                     /plasmid="P3"
                     /geo_loc_name="Spain"
                     /collection_date="2018"
     gene            complement(118..702)
                     /locus_tag="LQ146_RS27975"
                     /old_locus_tag="AI2617V1_5347"
     CDS             complement(118..702)
                     /locus_tag="LQ146_RS27975"
                     /old_locus_tag="AI2617V1_5347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004589499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351424.1"
                     /translation="MDITISDATYSRLAAQAKGFETPEQVINRLIDVVEIDHDTRPELF
                     FNPEGEADFKKALLKSKQAKVEMFKRDGSCETGVWNARAISEESSVRANIWSGYLRGWK
                     EKGIVRAVFTVQEVPDLPGAAESVQWNDYTISRTFSGGISVQRNGMPVTIVKPFLRDVA
                     HDLKISLLNSNGNEMNTRQLGAAIIKKLNNS"
                     /name="hypothetical protein"
     gene            complement(1149..1640)
                     /locus_tag="LQ146_RS27980"
     CDS             complement(1149..1640)
                     /locus_tag="LQ146_RS27980"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061351425.1"
                     /translation="MAIGDDAIRDAFYAFTQQAEEMDDKGLPQEVWETPCFTYLMTKKQ
                     FNQMKVVCQRNGWDIPASPAIPITWAMFRHVLSARNSKDKLSWQECAEILATAFSVQSN
                     VYVNRDYSEQTIVLNAVRRINVAGAGFFAMAIVDVSENNLAPVTAYHATEAKCKAIQRG
                     "
                     /name="hypothetical protein"
     gene            complement(1705..2196)
                     /locus_tag="LQ146_RS27985"
     CDS             complement(1705..2196)
                     /locus_tag="LQ146_RS27985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558888.1"
                     /translation="MREKTKTLTVRLPVSLIERIEQNAARTGATRTDAVIEALNAGLGT
                     KPEGMDTKLLAAIEALRAEVRALSVGGKPARQTAQQTAPQSAQQPARQIVPRGADPRFQ
                     AVSDEADQLIVSMTAENATLPAIASALNAAGHRTATGQEWNTSRVRDYRHKLRESGLLN
                     "
                     /name="hypothetical protein"
     gene            2724..4019
                     /locus_tag="LQ146_RS27990"
                     /old_locus_tag="AI2617V1_5349"
     CDS             2724..4019
                     /locus_tag="LQ146_RS27990"
                     /old_locus_tag="AI2617V1_5349"
                     /inference="COORDINATES: protein motif:HMM:NF017116.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="WP_119879886.1"
                     /translation="MSQIDENSGTAADNVTPIAAAKVGRPSLQKKYPTTAFPVELEINY
                     RKGRYSSSLENVVAAMRCHSVTGIQLAFDEFFAEEGAFVNGQWYPLSDNLVTELRLRLA
                     AADFEKVTKDNARDAMFYVCDENKFDSAQRWLTAQEWDGKPRVSYFFERCFKCQGDPEY
                     LAAVSLYTWTALAGRVMNPGIKADMVPLLYGRQGARKSTGVRLMSPFPDSYSSFNLNDK
                     DDSLVRRMRGCLIGELEELRGLHGRDSESVKAFFSAAHDEWVPKFKEFKVRNPRRVVFI
                     GTTNNKQILNDSTGNRRYLPMNSGDVDCAAIEKNRSQLWAEALHLFNENGVMWEAAETL
                     ARKVHDEFRVEDPWEDEIAELLKLDVDDCDPTAFVPTKALFSQVGLMIGHTSNKQHQRM
                     AAIMSRLGYEVGRKRINGALVRGYFRRTQAVV"
                     /name="VapE domain-containing protein"
     gene            complement(4665..5132)
                     /locus_tag="LQ146_RS27995"
                     /old_locus_tag="AI2617V1_5350"
     CDS             complement(4665..5132)
                     /locus_tag="LQ146_RS27995"
                     /old_locus_tag="AI2617V1_5350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324036.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_070559148.1"
                     /translation="MKKYTTEQKAQALRLLEQDGATAATVARTMGIPPRTVRDWAKART
                     DAPSNVLSIEEMRERAQRAVEATPQAAIRRLKNHFVQRQFELLQRHATDLQALRTASLQ
                     AMLEKDATMVKAISGLMTSLLKTQERERVIYEIKPGTEADIMREGMNRQQS"
                     /name="transposase"
     gene            complement(5331..5576)
                     /locus_tag="LQ146_RS28000"
                     /old_locus_tag="AI2617V1_5351"
     CDS             complement(5331..5576)
                     /locus_tag="LQ146_RS28000"
                     /old_locus_tag="AI2617V1_5351"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070558916.1"
                     /translation="MAFENIPRRFQRWKVIMVPGAKSYESWDEMVTGENFSEETRMKTY
                     KKHRTKAIDRTVANQEYIHTMTEDGITVRYRLERWR"
                     /name="hypothetical protein"
     gene            complement(5695..5880)
                     /locus_tag="LQ146_RS28005"
                     /old_locus_tag="AI2617V1_5352"
     CDS             complement(5695..5880)
                     /locus_tag="LQ146_RS28005"
                     /old_locus_tag="AI2617V1_5352"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879885.1"
                     /translation="MINQAATPRYPGLSIEHGEIRQFGKPRHCAANRKGQYQTTLRDSA
                     GRYQTVSIISLYAWEA"
                     /name="hypothetical protein"
     gene            complement(5991..6578)
                     /locus_tag="LQ146_RS28010"
                     /old_locus_tag="AI2617V1_5353"
     CDS             complement(5991..6578)
                     /locus_tag="LQ146_RS28010"
                     /old_locus_tag="AI2617V1_5353"
                     /inference="COORDINATES: protein motif:HMM:NF012464.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_181654175.1"
                     /translation="MSKTYGYVRVSTDEQTSNSQRDAIIARFPTASILADDGISGTVPP
                     RERPALGILLNQILQEGDTLVIYAIDRIGRNARDALELVEELEKRKVTLVSIREGVDLS
                     SAVGQAVLGIMASFAQMERKLILERQAAGIEAAKSRGQKFGRPTKIGAKEAGEIVMRRA
                     MGVPIATIAKQLNLSRSAIYRHLEKVDAVAPE"
                     /name="recombinase family protein"
     gene            6838..7494
                     /locus_tag="LQ146_RS28015"
                     /old_locus_tag="AI2617V1_5354"
     CDS             6838..7494
                     /locus_tag="LQ146_RS28015"
                     /old_locus_tag="AI2617V1_5354"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_119879883.1"
                     /translation="MTEIKTECPDATWLRTTLAEMASDHFPVYDLPCLSVDPNSSAQLT
                     ALDDRRVAREMRQAAADVETRRIDAARVVEGLRTEAERLRGLIADGKTALRAGETVSPD
                     AGVAAFLLPDIEAELVAAEAAEADVARERDALLQDADRRDAAAAIGLFNLAHAVRVQRI
                     EQLLKLAMDEATLLAESDAGRSLYRTVINPDRRLNQLFSTQGAIEILRRNRGMEA"
                     /name="hypothetical protein"
     gene            7495..7878
                     /locus_tag="LQ146_RS28020"
                     /old_locus_tag="AI2617V1_5355"
     CDS             7495..7878
                     /locus_tag="LQ146_RS28020"
                     /old_locus_tag="AI2617V1_5355"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559064.1"
                     /translation="MSAFSMLCDRLRHEATLAKSTGAGDALAQVLETGGAAQTFAPIGA
                     PVASPTESVHRARAQSIQDAAFLTEMKQAGVAPADLVMLDGVLASSRGLPDASRAPAFA
                     AVRAQVQQQASLSPAARGINWDE"
                     /name="hypothetical protein"
     gene            7884..8240
                     /locus_tag="LQ146_RS28025"
     CDS             7884..8240
                     /locus_tag="LQ146_RS28025"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070559062.1"
                     /translation="MPRHLQGKTRMPLAGGCYSAGHRLALISLLPVLEARPGDRDDGER
                     SKLALYQESLIKAGQPHAFALHEPSLYRWGAYLKSRRARYLQETDAGVAAASDALDRHA
                     FGRAIGAVLGADDE"
                     /name="hypothetical protein"
     gene            complement(8398..9039)
                     /locus_tag="LQ146_RS28030"
                     /old_locus_tag="AI2617V1_5356"
     CDS             complement(8398..9039)
                     /locus_tag="LQ146_RS28030"
                     /old_locus_tag="AI2617V1_5356"
                     /inference="COORDINATES: protein motif:HMM:NF016255.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_070559060.1"
                     /translation="MTETTRPILTIKRRNRTVYVPPEKAAKSEPQPAERTTSKAKVQPK
                     AKAPQKPAQKPTAAKPKKTPEQVAEGIRRQEENDRRQQDIAIANKSKKALANRVTKAFL
                     KEHWPDLLTRGVDRRPMAKGIIEQILTRGAELNMPPEADRKAVRRILGIVTGTSSYQQS
                     LIDQCMRYDLDGNPTEPATPEEAENAKARLTEIKAFRRKARQAKGEKKGA"
                     /name="ProQ/FINO family protein"
     gene            complement(9036..10325)
                     /locus_tag="LQ146_RS28035"
                     /old_locus_tag="AI2617V1_5357"
     CDS             complement(9036..10325)
                     /locus_tag="LQ146_RS28035"
                     /old_locus_tag="AI2617V1_5357"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_157698538.1"
                     /translation="MNDDNDTTEATQPSTEALKCVGAAERFPDIMPGVLFVTCPGGCSL
                     RVEACRQIYEQSHLDRTIENPHLECHRCPTGLALWVGTEQPPDAPLTTPADTRKLCPRC
                     SRKDNRLIAPNKPGSSLCVSCWNREREATIGANARGRVNRTPPFVSPFLIGIGDGWQVW
                     YGIHQGEALVRAMRANPGARFHDRRPGPVGQTRRDGFVYYCPEHREPLRWNGGDGHAGE
                     VELACPRCQPWAAPLSVAPTFQTVSFQTPHDAAHQYRNATLPDNAVWTSSVCADCKAAP
                     LVISKAPVKGKPRREIVVSCPSCDSSASARPGGRTWTDEHIAVPEFAQNETRSLAKIPV
                     ILPQGEQPQLLKRPGTGRGPGRPRKRIPLTLDRVPESRFNRLALSVLAAVGRWDYINDI
                     IRRIDRNRGDAATLIALADHIRTNRPERDL"
                     /name="hypothetical protein"
     gene            10681..10890
                     /locus_tag="LQ146_RS28040"
     CDS             10681..10890
                     /locus_tag="LQ146_RS28040"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765954.1"
                     /translation="MKKRIYTADLAALLNVSLRTLSRLSSRGIVPTPAGRSLRGGHYWL
                     AGDPVLKRFIADQRRPGRAPYGVR"
                     /name="hypothetical protein"
     gene            10877..12058
                     /locus_tag="LQ146_RS28045"
                     /old_locus_tag="AI2617V1_5358"
     CDS             10877..12058
                     /locus_tag="LQ146_RS28045"
                     /old_locus_tag="AI2617V1_5358"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765953.1"
                     /translation="MAFDNSHLTDAGLFWRAVSAAGAPVDREDWLRLCSGIACWASLCG
                     EDGLAAIEAWSTRHNRGSAHHRSQYRHFLKLKGVTNPEAMAQVFLRFSGEVYWRLDSNR
                     TPPSTEQVAALAERKRRSIEAVARREDADRRKADKAAADAVRMLAKGDGNPAYTPYWRN
                     KTTIARRGGVSLPPLPADLRVGGLFRSFEPRAYWSRCLLVPAYRLTDDRQLVGDALEAI
                     CGVCSAGGKTGDKFSPAGTQKAGRFYPMPGFMDVLDTSPHAPYSPLFVCEGFATAVALH
                     HLTKGKVAVCAAFSIAGFGSCVASLRRFWPDVDVMLVPDHGEAYRLAHKAAYGDEREPV
                     PTIPGAAVVSFDGLDRFTPRDNLDWFDVLVEEGEDRARELLRYAVRHARLERR"
                     /name="hypothetical protein"
     gene            12284..12742
                     /locus_tag="LQ146_RS28050"
                     /old_locus_tag="AI2617V1_5359"
     CDS             12284..12742
                     /locus_tag="LQ146_RS28050"
                     /old_locus_tag="AI2617V1_5359"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088765952.1"
                     /translation="MKSKTELREAATARSLAVIATEMSEWSLDGFSHLKLPNFSAGERQ
                     QTLSGSVVVDRPPFDYEWAGTEKFNTLATRALQVKLPASRERNYAWLCGVERETLATAL
                     LVELFSVTGCVAFAGLGKVADLAFLTLDESEAGQIRAAMLQWLDGAAA"
                     /name="hypothetical protein"
ORIGIN
        1 ctgatgacag gtggcgggcg ttctgcctcg ccagctatga atggtgcgta ttcgtcgcag
       61 tagaactctg accggcggcg gcgttgagcc gtcgctcctc tgcgtgaagc atcgatgtta
      121 agagttattt aacttcttta tgatcgctgc gccaagctgc cgagtattca tttcatttcc
      181 attgctattt agcaatgata tttttaaatc atgcgcaaca tcacgtagaa atggcttcac
      241 aatagttaca ggcatgccat ttctttgaac tgaaataccg ccactaaaag tgcgactgat
      301 tgtataatca ttccactgca cactttcagc cgctcctggc aagtcaggaa cctcctggac
      361 agtgaaaacc gcacgaacaa tccctttttc cttccatcca cgcaaatacc cactccaaat
      421 atttgcccga actgatgatt cttctgaaat cgcacgagca ttccatactc cagtttcaca
      481 ggaaccatcc cttttaaaca tttcgacttt ggcctgtttt gattttagta acgctttttt
      541 aaaatccgct tcaccttcag gattaaaaaa aagttcaggg cgtgtgtcat gatcgatttc
      601 aacaacatcg atcagacggt ttattacctg ttcgggagtt tcaaatccct ttgcttgtgc
      661 agcaagacgg ctatatgtag cgtcagatat cgtaatatcc atcaaagtac ctctatagat
      721 caaaaattaa tcataaaatt aatcataatt gataaattta atgatttcaa gatctataat
      781 tacctgatat cgcaatatgg ttaaccgcct ctaaagagct ataaaaacct gtaaacccgc
      841 tcctcgtgcc gcttggttat aaacaaacca gttgaatcta cgtcaacaat agcctactat
      901 tgttgtactg caagagcatt cgcagggggt attaaccagt aattaaccct ttgcgctggg
      961 cagtcaggag gctggtctcc tgttgggaag ttatgttgcg gcttcctagt aataacagtg
     1021 aatttgatag acagcagaaa accgccgatg ctgctagatc cgaaaggaac caatgaaggg
     1081 aaatatttag gcgttatggt tcattctcat taaattgagg agaattgctt aaatgggcgt
     1141 ccttcctatc accctcgctg tatagcttta catttggcct ccgttgcatg gtatgcagtc
     1201 acgggggcca aattattttc agagacatca actatcgcca ttgcgaaaaa gccagcccca
     1261 gcaacgttaa tgcgacgaac agcattgagc acaatagtct gctccgagta atctctgtta
     1321 acgtacacat tgctctgcac tgagaatgca gttgccaaaa tctccgcaca ctcttgccaa
     1381 cttagcttat ccttcgagtt acgagcagat agcacatgcc taaacattgc ccaagtgatc
     1441 ggtattgctg gtgatgcagg tatgtcccag ccgtttctct gacaaacaac tttcatttga
     1501 ttgaactgct tcttagtcat cagataggta aaacaaggcg tctcccaaac ttcctgaggg
     1561 agacctttat catccatttc ttcagcttgc tgtgtaaaag catagaaagc gtcacggata
     1621 gcatcatcac cgatagccac ttcttttcct tgtaaaattt ttatgttcga attttatcat
     1681 atttagctat gtcacttagg actgctaatt cagtagccca ctttcccgca acttatggcg
     1741 atagtcccgg acacggctgg tgttccactc ctgtcccgtc gctgtccggt gccctgctgc
     1801 gttcagtgcc gacgcgatgg cgggcagagt cgcgttctct gcggtcatgc tgacaatgag
     1861 ctggtcagcc tcatcactga cggcctggaa gcgcggatcg gctccccggg ggactatctg
     1921 tcttgcaggt tgttgtgcgc tttgtggtgc tgtttgttgt gcggtttgtc gtgcaggttt
     1981 accgccgacg gacagcgccc tgacttcagc cctcagcgct tcgatggcag ctaaaagttt
     2041 ggtgtccatc ccttccggct tcgtgccaag tccggcgttc agcgcctcta tgacagcatc
     2101 cgtgcgggtt gctccggttc gtgctgcgtt ctgctcgatg cgttcgatca ggctaacggg
     2161 taggcgaacg gtcagggttt tggttttctc tctcatggct gctgctctcc acgtcgtgcg
     2221 ttttgtcgtg ctgtttgtct tgcgtagtgt aatgcgtttt gtcgtgcgcg tcgaattcga
     2281 cgtcgtgcag ttgtcgtgca cagaggggcg acggctttgc gtcgccgggg tgccgtttgt
     2341 gtacatggat aaatagcaga ggcggcgcag agattgagct gggcgtgatc acgacagcgc
     2401 gataagtgcg cggcgctaag tggcgtggag ggttgggatc gggtaagctg atctggcgtc
     2461 tgcggatccg gttggggatc ttcgggcaca aaaaaaggcg acctgttggg tggtcacctt
     2521 tttctgccgg gggagctggt aactcctccg attaattcga gtcacgtctt agcgggacgt
     2581 tctcgaagga agaatagcac ttgcgcagcg tactcctcaa actcaaagag aagtgtacca
     2641 cgtcgataag atcgcgcaag tgtgaatttc cctcgtaagc ccccgcctga cgccgactcc
     2701 tacgttttta aaggagtaat tgcgtgtcac aaattgatga aaattccggc actgctgccg
     2761 acaacgtaac gccgatcgcc gctgccaagg tgggacgccc gtctctacaa aaaaaatacc
     2821 cgactaccgc gtttcccgtg gagctggaga tcaactaccg gaaggggcgc tactcgtcct
     2881 ctcttgagaa cgttgtcgcc gctatgcgct gccattccgt caccggcatc cagctcgctt
     2941 tcgatgagtt ctttgcggag gagggggcgt tcgtgaacgg gcaatggtac ccgctgtccg
     3001 acaacctagt taccgagctg cgtctgcgcc tcgctgctgc cgacttcgag aaggtgacca
     3061 aggacaatgc ccgcgacgcc atgttctacg tctgcgatga gaacaaattc gacagcgccc
     3121 agcgttggct gacggctcag gaatgggacg gcaaacctcg cgtcagttac ttcttcgagc
     3181 ggtgcttcaa atgccaaggg gatcccgagt acctggcggc ggtcagcctc tacacctgga
     3241 cggcgcttgc cgggcgcgta atgaatcccg gaatcaaggc cgacatggtt ccgctgctgt
     3301 acgggcgaca gggtgcccgc aaatcgacgg gcgttcgcct tatgtcgcca ttccctgact
     3361 cctactccag cttcaacctg aacgacaagg acgactccct agtgcgccgt atgcgtgggt
     3421 gcctgattgg cgagctggag gagctgcgcg gcctccacgg gcgcgactcc gaatcggtga
     3481 aagcgttctt ctccgctgcc cacgacgagt gggtgccgaa atttaaagag ttcaaggtgc
     3541 gaaacccgcg ccgcgtggtg ttcatcggta ccacgaacaa caagcagatc ctcaatgact
     3601 cgacggggaa ccgccgctat ttgcccatga attccgggga cgtggactgc gcggccatcg
     3661 agaaaaaccg ctcgcagctg tgggctgaag cgctccacct gttcaatgag aatggggtga
     3721 tgtgggaggc cgctgaaacg ctggcgcgta aggtgcatga cgagttccgc gtcgaggatc
     3781 cgtgggaaga cgagatcgcc gagctgctca agctggacgt tgacgactgc gacccgactg
     3841 ctttcgtgcc gacgaaggcc ttgttctctc aggtagggct catgattggc cataccagca
     3901 acaagcagca tcagcgcatg gcggctatca tgtcccgatt gggctatgag gttggcagga
     3961 agcgcataaa cggtgcgtta gttcgtggct acttccgtcg aacgcaagct gtcgtgtaag
     4021 ggttactttt ccgtaagagg ggagctatat gctccccttt tttattgttc cacccgggtg
     4081 gatcacgggt ggatcatcac gccgtttttg taccacctgt tccacccggg tgttccaccc
     4141 gttccacccg tgttccgccc gtggatggaa cagctaaggc ctcgtgttta aaggctttca
     4201 ttgttgtgtt ccacccgttc caccctattt tctaattaaa aacaaaaaat gaataaattg
     4261 ggtaaatagg gggtaaatgc tcactaattg aacaattagt tgtttttttt actatttatg
     4321 aatctatgcc ggatcgggtg gaacgggtgg atcatcttgg aatcgacgcg ccgcagctgc
     4381 accctgccgg atgcactttg cttgtcttat tagatcggtg gatgggttcg tcgtgccggg
     4441 atggtcggtg gtagtggttc tgagggggat cggaggtttg ggtggcgctg agggcacgag
     4501 gctttcgcct cgcgctgggt ggtcgtctgt tggttctgcg tgagggcttg ccctcgcgca
     4561 cgcgagcggt aacaactcgt taacgtgcgg atccgcgtat ttcgcgggct cccgggtttt
     4621 ctgcggcggt aaagcggcgg taaaaggcgg ttttcccgcc gttttcagct ctgttggcga
     4681 ttcatgccct cgcgcatgat gtcggcctcg gtgcctggct tgatctcgta gatgacgcgc
     4741 tcgcgttcct gcgtcttgag tagggatgtc ataaggccgc tgatcgcttt gaccatggtg
     4801 gcgtccttct ccagcatggc ctgtagcgaa gctgtgcgga gggcttgcag gtcggtggcg
     4861 tggcgctgta gcagctcaaa ctggcgctgt acaaagtggt tttttaggcg tcggatcgct
     4921 gcctgtgggg tggcctcgac ggctcgctgt gcgcgttcgc gcatctcctc gatgctgagg
     4981 acgttgctgg gtgcgtcggt gcgggctttc gcccaatctc tgacggtgcg gggtgggatc
     5041 cccatggtgc gtgcgacggt ggctgcggtt gcgccgtcct gctccagtag tctgagcgcc
     5101 tgggctttct gctcggtggt gtatttcttc atggtgtcct gctccggttg gtttctctcc
     5161 tgtattgaaa cgtcacgcgc tgaaaatggc gggggttttt ggggggtaca cggcgtttgt
     5221 gcgtgcgtgg tcgtgcggtt gggtattttt gtggctgagg cgcttagaat ggctctggtg
     5281 cgttctgggt aagggaggag gcgcagcagt cgctgcgctc ctagctgggg ttagcgccag
     5341 cgttcgaggc ggtacctgac ggtgatcccg tcctccgtca tggtatggat gtactcctgg
     5401 tttgccacgg tgcggtcgat ggccttggtg cggtgctttt tgtacgtttt catcctggtt
     5461 tcttcggaga agttctcgcc ggtaaccatc tcgtcccatg actcatatga ctttgctccg
     5521 ggaaccatga ttaccttcca tctctggaac ctacggggaa tgttttcaaa tgccatcgtt
     5581 ctctccttat gattctggtt tctgggggcg ctcccgcgcc cctgtaagtg gttcgtaatg
     5641 gcgtaaggct tttgttattg cttgctgctt acacctgtaa ggctttcgtt atggtcatgc
     5701 ttcccaggcg taaaggctga tgatgctgac tgtctggtac cgaccggcgc tgtcgcggag
     5761 ggtggtctgg tactggcctt tgcggttggc ggcgcaatgg cggggcttgc cgaactggcg
     5821 gatctcgccg tgttcaatgc tcaggccggg atagcgcggt gttgctgctt ggtttatcat
     5881 ggttctgttc cttgttggga atggtgcccg ggtctgctcc tcatgcgttc cccgggctgg
     5941 gttgcggcgg tgtggaatgg ttggagccac ctacaccgct gcgctctctc ttactccggc
     6001 gctaccgcgt cgaccttctc aaggtggcgg taaatcgcgc tcctgctcag atttaactgc
     6061 ttggctatgg tggctattgg tacccccatg gcgcggcgca tgactatctc ccccgcttct
     6121 ttcgcgccga tcttggtcgg gcgtccgaac ttctggccac ggctctttgc ggcctcgatc
     6181 cctgccgcct ggcgttccag tatgagcttg cgctccatct gcgcgaaact cgccatgatg
     6241 ccgaggacgg cctgtccgac ggcgctgctc aaatcgacac cctcgcggat gctgaccagg
     6301 gttacttttc gtttctccag ctcctcgacc agttcgaggg cgtcccgggc gttcctgccg
     6361 atgcggtcga tcgcgtagat gaccagcgtg tcgccctcct gcaggatctg gttcaggagg
     6421 atgccgaggg ctggacgctc gcgtggtggt accgtcccgc tgatcccgtc gtcggcgagg
     6481 atggaggctg ttgggaaccg ggcgatgatg gcgtcgcgct ggctgttgct ggtttgttcg
     6541 tcggttgata cgcgaacgta accgtatgtt ttgctcactt ttttctctcc tctgaccgat
     6601 acgtctcttt cgacacaaca tgccacaact gtaccgaaag tctatcgcta aagtgtctat
     6661 ttcgtcgctt tgtcgggtgt cccggaatgt aggggattag cgacggcctc caggcggctc
     6721 tccgcgctgg gcgagagccc tgcgccctct gcgttgatgt ctgcgcggtg tcgtgacggc
     6781 atgctgtctg agcggcgttt gctgccgctt tgctgataac ttgctgagaa ccaaaccatg
     6841 accgaaatca aaaccgaatg cccggacgcg acctggctgc gtaccacgct tgctgaaatg
     6901 gcgagtgacc attttcccgt ttatgacctt ccttgcctgt cggtggatcc taactcctcc
     6961 gctcaactta ccgcgcttga cgatcgccgg gtggcgcgtg aaatgcgtca ggcagcagcc
     7021 gacgtggaaa cgcgacgcat tgacgccgct cgcgtggtgg aagggctcag gacggaagct
     7081 gaacgcctgc gcgggctgat tgccgacggc aagacggcgc tgcgtgctgg cgagactgtg
     7141 agccccgatg cgggcgtcgc tgcgttcctg ctgccggata tcgaggccga gctggttgcc
     7201 gccgaggctg ctgaggctga tgtggcccgg gagcgtgacg cgctgctgca ggatgctgac
     7261 cgccgtgatg cggcggctgc gatcggcctg ttcaacctgg cgcacgccgt gcgcgtacag
     7321 cgtattgagc agctgctgaa gctggcgatg gatgaggcga cgctgcttgc cgagtccgac
     7381 gcggggcgca gtttgtaccg tactgttatc aatcctgatc gccgcctgaa ccagctgttc
     7441 tccacgcagg gtgcgatcga aattctgcgc cgcaatcgcg gcatggaggc gtaaatgtct
     7501 gcattttcga tgctgtgtga ccggcttcgc catgaggcga cgctggcaaa atctaccggg
     7561 gccggcgacg cgctggcgca ggtgctggag acgggcggtg ctgcgcagac gttcgcgccg
     7621 atcggggctc cggttgcctc tcctacggag tcggttcacc gggcgcgtgc tcagtccatc
     7681 caggatgcgg cgttcctgac tgagatgaaa caggcgggcg tggctcctgc cgatctggtg
     7741 atgcttgacg gcgtgctggc ctcctctcgc ggactccctg atgcgtcgcg tgctccggcg
     7801 ttcgctgcgg tgcgtgctca ggtgcagcaa caggcgtctc tctcccctgc tgcccggggt
     7861 atcaattggg acgagtaaag ccgatgccgc gccacctgca gggtaagacg cggatgccgc
     7921 tggcaggtgg ttgttactct gctggccacc gtcttgcgct gatctcgttg ctgcctgttc
     7981 tggaggctcg tcctggtgac agggatgatg gtgaacgatc gaagctggcg ctgtatcagg
     8041 aatcgctgat caaggccggg caaccgcacg cgttcgcgtt acatgagccg tcgctgtatc
     8101 gctggggggc gtatctgaag agccgccgcg cccggtattt acaggagaca gacgcaggtg
     8161 ttgctgcggc ctcagacgcg cttgatcggc atgctttcgg gcgtgctatt ggtgcggtcc
     8221 tgggggctga tgatgagtga gtttgccgtc tcgcgtctgg tcatccctga ggtggtgatc
     8281 cctgacgggg ttgttgctgc gcgaaaggcc agggggatcg cgcaacgtgt cgcagctgct
     8341 cgccgtgctg ctgaacgtcg tgctgcgcct acatggtgct gggtgagacg gggcgcgtta
     8401 tgcgcccttt ttttcgccct tcgcctggcg tgccttgcgc cggaatgcct tgatctctgt
     8461 caggcgggct ttggcgtttt cggcctcctc cggggttgct ggttcggtgg ggttgccgtc
     8521 caggtcgtag cgcatgcact ggtcgatgag gctctgctgg tacgagctcg tacccgtgac
     8581 aatgcccagg atgcgacgga cggctttgcg gtctgcctct ggcggcatgt tcagctctgc
     8641 gcctcgggtc aggatctgct cgatgatgcc ctttgccatg gggcgacggt caactccccg
     8701 ggtcagcaag tcaggccagt gctctttcag gaatgctttg gtcacccggt tggccagcgc
     8761 ctttttggac ttgttggcga tcgcgatgtc ctgctggcgg cggtcgttct cctcctgtct
     8821 gcggatcccc tcggcgacct gttcaggcgt ctttttcggc tttgccgctg tgggcttctg
     8881 tgcgggcttc tgcggggctt tcgcttttgg ctgtaccttc gccttgctgg tagtccgttc
     8941 ggctggctgc ggctcagatt tcgcggcctt ttccggcggg acgtagaccg tgcggttgcg
     9001 tcgcttgatg gtcaggatcg gacgggtggt ttcggtcata aatctctctc tggtcggttg
     9061 gtccggatgt ggtcggcaag ggcgatcagg gtggcggcgt cgccgcggtt ccgatcgatg
     9121 cgccggatga tgtcgttgat gtagtcccag cgcccgacgg cggcaaggac ggaaagggcg
     9181 aggcggttga accggctctc tggtacccgg tcgagggtca gggggatgcg cttgcggggg
     9241 cgtcctggac cgcgccctgt ccctggtctt ttgagcagct gcggctgctc cccctgcggc
     9301 aaaataacgg ggatcttcgc caggctgcgc gtctcgttct gcgcgaactc gggcaccgcg
     9361 atgtgctcgt ctgtccatgt cctgcctccg ggcctggctg atgcgctgga gtcgcaggac
     9421 gggcaggaga cgacgatctc ccgtcgcggc ttgcccttga ccggtgcctt gctgatcacc
     9481 aggggcgcgg ctttgcaatc agcgcagacc gacgatgtcc agaccgcgtt gtctggcagg
     9541 gtggcgttcc ggtactggtg cgcggcgtca tgcggtgtct ggaagctgac cgtctgaaac
     9601 gtgggggcga cgctgagagg tgccgcccat ggctggcacc tgggacaagc aagctccacc
     9661 tctccggcgt gcccgtcgcc accgttccag cgcaggggct cgcggtgttc ggggcagtag
     9721 tacacgaaac cgtcgcggcg tgtttgcccg accgggcctg gtcggcgatc gtggaaccgt
     9781 gcgcccgggt tggctcgcat ggcgcggacg agcgcctcgc cctggtggat gccgtaccag
     9841 acctgccagc catcgccgat gccgatcagg aacggcgaga cgaacggtgg ggtgcggttg
     9901 actctcccgc gtgcgttggc tccgatggtg gcttcgcgtt cgcggttcca gcaggagacg
     9961 cacaggctcg aaccgggctt attgggggcg atcaggcggt tgtctttccg gctgcaacgg
    10021 gggcagagct tacgggtgtc tgccggggtg gtcagtggtg cgtcaggggg ctgttcggta
    10081 ccgacccaaa gcgcgaggcc agtggggcac cggtggcact cgaggtgggg gttttcaatc
    10141 gtgcgatcga ggtggctctg ctcataaatc tgtcggcatg cctcgacccg gagggagcac
    10201 ccgccggggc aggtgacgaa caaaacgccg ggcatgatgt cggggaaccg ctccgcagcg
    10261 cctacgcact tcagtgcctc ggttgacggc tgcgtcgctt ctgtcgtgtc gttatcgtcg
    10321 ttcactgctc cccctgcgtc gaaatggtcg ccagacctcg ccagcactgg ctgtgcgtct
    10381 tttttagtat ctcacaaaaa acgccacttt ggcgttaatt gtgttaagct tgtcttactg
    10441 attcctgacg agcagttggg aaacatgaaa ccggatcgcc cggtgccgct ttccctcctc
    10501 cccaacgagg cggggttgta aacgaggatg cgcgcttcgt ccttggcagg tgcgagtaag
    10561 cgagaagggc tgctgtcctg ccgctatgcg gtaagtcctc aagggcggct ttatcgataa
    10621 tcgtcactcc cgccccccga tgcccgttaa gctgaggggg gcacctatct ggtactccca
    10681 atgaaaaaac gaatctatac cgctgacctc gctgcgctgc tgaacgtgtc gctgcgcacg
    10741 ctctcccgcc tgagttcgcg ggggatcgtt ccgactccgg cagggcgttc ccttcgtggc
    10801 gggcattact ggctggctgg ggatcccgtg ctcaaacgct ttattgccga ccagcgtcgt
    10861 cccgggaggg ctccttatgg cgttcgataa ctctcacctg actgacgctg gcctgttctg
    10921 gcgtgccgtc tctgcggctg gggctccggt tgaccgcgag gactggctgc gcctctgttc
    10981 tggcatcgca tgctgggcat ctctctgcgg agaggacggg cttgctgcta tcgaggcctg
    11041 gtctacccgc cacaatcgcg gatctgcgca tcaccggtcg cagtaccggc acttcctgaa
    11101 gctgaaaggc gtaaccaatc ccgaggccat ggcgcaagta ttcctgcggt tctcaggcga
    11161 ggtgtactgg cggctcgact caaatcgcac gccgccgtcg actgaacagg ttgctgctct
    11221 tgctgaacgg aaacgccgat cgatcgaggc ggtggccaga cgcgaagatg ccgaccggcg
    11281 caaggccgat aaggctgcgg ctgatgcggt caggatgctg gcgaaaggcg acggtaatcc
    11341 ggcctatacc ccgtactggc gcaataagac cacaatcgcc aggcgtggtg gcgtcagcct
    11401 cccgcccctc cccgctgacc ttcgtgtggg tggcttgttc cgctcgttcg aaccgagggc
    11461 gtactggtcg cgctgtctgc ttgttcctgc ctatcgcctg accgatgatc gccagctggt
    11521 tggcgacgcg ctggaggcca tctgcggcgt ctgctctgct ggcggcaaaa ccggcgacaa
    11581 gttctcccct gcaggtaccc aaaaggcggg acggttctat ccgatgcccg gctttatgga
    11641 cgtgctcgat acctcaccac atgcgcccta ctcgcctctg ttcgtctgtg aggggttcgc
    11701 cacggcggtt gccctgcatc atctgacgaa gggcaaggtg gcagtctgcg cggcgttctc
    11761 aattgccggg ttcggcagct gcgtggcgtc gctgcgccgg ttctggccag atgttgatgt
    11821 gatgctggta ccggatcacg gcgaagcgta ccgcctggcg cataaagcgg cctatggcga
    11881 tgagcgagag ccggtcccga caattccagg cgcggcggtt gtgtcgttcg acggcctcga
    11941 tcgcttcacg ccccgggata acctcgactg gttcgacgtg ctggttgagg aaggggaaga
    12001 tcgggctcgt gagctgctgc gctacgcggt tcgtcatgcc cggcttgagc ggcgttgatt
    12061 ggcgtgtccg aatggtgcgc ctttcgggac atcttttttg ccgtcgtggc gtctggttta
    12121 gcgaacgact ttcgagacac taccgatgct tttttgatga gacggactaa agcgacgcac
    12181 cggcgctgcc gtcgtgacgc tatcctgcga tcggtttctc acagcagcat aaagcccggc
    12241 ctcgtcttga tgtcgggttt ttttttagcc caaaggaggg cacatgaaat caaagactga
    12301 actacgcgag gccgcgacgg ctcgctctct ggcggtgatc gccactgaaa tgtcggagtg
    12361 gtcgctcgat gggttctccc acctcaagct gccgaacttc tccgctgggg aacgccagca
    12421 gacgctgtcc gggtcggtgg tggttgatcg cccgccgttc gactacgagt gggctggtac
    12481 cgagaaattt aacactctgg ccacccgtgc gctgcaggtg aaacttccgg catcgcgtga
    12541 gcgtaactac gcctggttgt gcggcgttga acgggagacg ctggcgacgg cgctcctcgt
    12601 ggagctgttc tccgtcaccg gctgcgtggc gttcgccggg ctgggtaagg ttgccgatct
    12661 ggcgttcctg acgctggacg agagcgaggc ggggcagatc agggcggcga tgctgcagtg
    12721 gctcgatggg gcggcggcgt aggggctcga tcctcgatca gctggagtgg gaagggcgac
    12781 tgatcgagga ggccatggcg acggaactgc ggggcgaccc ggtgcgctgc gaccaccttg
    12841 ctgcggcgcg gttatggctg gagtgtgttg accgggcgt
//
