LOCUS       NZ_OU015949             7670 bp    DNA     circular CON 30-MAY-2024
DEFINITION  Enterococcus faecium isolate USZ_VRE5_P5 plasmid pl3, complete
            sequence.
ACCESSION   NZ_OU015949
VERSION     NZ_OU015949.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA8659929
            Assembly: GCF_907176135.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1
  AUTHORS   Boumasmoud,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2021) UZH, Raemistrasse 100, Switzerland
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_907176135.1-RS_2024_05_30
            Annotation Date                   :: 05/30/2024 03:51:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,125
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,908
            CDSs (with protein)               :: 2,908
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 40 of 124
            Pseudo Genes (incomplete)         :: 77 of 124
            Pseudo Genes (internal stop)      :: 26 of 124
            Pseudo Genes (multiple problems)  :: 15 of 124
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OU015949.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /isolate="USZ_VRE5_P5"
                     /isolation_source="Superficial wound"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pl3"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2015"
     gene            complement(<277..422)
                     /locus_tag="KKQ94_RS15675"
                     /pseudo=""
     CDS             complement(<277..422)
                     /locus_tag="KKQ94_RS15675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /name="plasmid mobilization relaxosome protein MobC"
     gene            complement(723..1166)
                     /locus_tag="KKQ94_RS15285"
     CDS             complement(723..1166)
                     /locus_tag="KKQ94_RS15285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223917876.1"
                     /translation="MGQYHYKLVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGT
                     WQTKDHSERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLT
                     LRSNKKQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
                     /name="hypothetical protein"
     gene            complement(1139..1633)
                     /locus_tag="KKQ94_RS15290"
     CDS             complement(1139..1633)
                     /locus_tag="KKQ94_RS15290"
                     /inference="COORDINATES: protein motif:HMM:NF017364.4"
                     /GO_function="GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="WP_250133724.1"
                     /translation="MINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYP
                     NLNNSQIESKSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGN
                     YSNSRHALALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITN
                     W"
                     /name="C47 family peptidase"
     gene            1836..2240
                     /gene="tnpA"
                     /locus_tag="KKQ94_RS15295"
     CDS             1836..2240
                     /gene="tnpA"
                     /locus_tag="KKQ94_RS15295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="WP_002287522.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMF
                     WSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
                     /name="tnpA"
     gene            2257..3405
                     /gene="tnpB"
                     /locus_tag="KKQ94_RS15300"
     CDS             2257..3405
                     /gene="tnpB"
                     /locus_tag="KKQ94_RS15300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="WP_002287525.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYEE
                     VKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRFKS
                     KKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKY
                     YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLS
                     RRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKD
                     GKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
                     /name="tnpB"
     gene            complement(3546..4175)
                     /locus_tag="KKQ94_RS15305"
     CDS             complement(3546..4175)
                     /locus_tag="KKQ94_RS15305"
                     /inference="COORDINATES: protein motif:HMM:NF026081.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphopain proregion domain-containing protein"
                     /protein_id="WP_250133723.1"
                     /translation="MKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQPIEEQ
                     AINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFSDADNT
                     IKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNGQIKLLW
                     KSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAGELLTT"
                     /name="staphopain proregion domain-containing protein"
     gene            complement(4798..5214)
                     /locus_tag="KKQ94_RS15310"
     CDS             complement(4798..5214)
                     /locus_tag="KKQ94_RS15310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002368067.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSYE
                     PNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKIEN
                     QLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
                     /name="hypothetical protein"
     gene            complement(5216..5497)
                     /locus_tag="KKQ94_RS15315"
     CDS             complement(5216..5497)
                     /locus_tag="KKQ94_RS15315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002368064.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIENDF
                     DQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
                     /name="hypothetical protein"
     gene            complement(5793..6281)
                     /locus_tag="KKQ94_RS15320"
     CDS             complement(5793..6281)
                     /locus_tag="KKQ94_RS15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_060763418.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKEA
                     VTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQQK
                     LLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQFWQ"
                     /name="DUF536 domain-containing protein"
     gene            complement(6291..7259)
                     /locus_tag="KKQ94_RS15325"
     CDS             complement(6291..7259)
                     /locus_tag="KKQ94_RS15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_002368293.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQF
                     TFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKIDGK
                     ADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIANFS
                     KEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGYQFTF
                     KPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELLQQLAE
                     LERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
                     /name="replication initiation protein"
     Typing          complement(6292..7259)
                     /name="rep_cluster_1093"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gcttaaaaac agttcgtaag gagtcctttt agaagctctg agcgctcatc tacggcgttt
       61 taagacaagt ctagataaaa tcccttatct tgtttttaaa gcgccttaca ggcggtcagg
      121 gcaagcccta acaaccctaa aacgttctac agaacctcta aaattcgttt taaggcgttt
      181 taaagtcgct ttggtataat tacataccag aacgtttaaa acgccttaaa acgcaaatta
      241 gagccctatg tatatatcga ctaatgttac ctagactttt acggaagccg gcacactcat
      301 ttgcaaagct tcagagttgc aaatttggat tcgctcactc gaaaactgat ttattttgac
      361 tctgatcaat aggtgtattt tttagaagga ttgctagcca aattttgctt taatttgctc
      421 ataagtccca cccttttgat acgtcctatg gacgtatcgt ttgtaatgtg aaagtgacta
      481 taaggtccct ttctacaaaa cacactaaag ggcttggcaa gctctatatt tgctagccaa
      541 atacctacgt atttggtgca aataaccgct tgtcaaaggg gcgcaagctc ccccttgaat
      601 ccccctcaaa acccacgctc cacaatacaa aaaaggctag caaatgctag ccactttttg
      661 taaagtttcg cttgtttcac cttcggtgaa attattgttt tgtaatatca aacaactatt
      721 catcaatcag ctttaaaaaa ttcaattggt ttagctgtcc cttctgtccc atcattcgtt
      781 gtcaaaataa atacgagctt ttttggagaa tccaaactaa aagtgtaatc taattgtttt
      841 ttattcgagc gcagtgttag taaattattt gttgctttgt aaatgaaaac ttgttcattt
      901 atatttaaat ttttatcaat gatttgaatt ttatgattgt tctcttttac taagatggta
      961 tattgttcta tattttttga agtatttaaa ttagtgatta ctagacgttc tgaatgatct
     1021 ttagtttgcc aagttcctag aaaaggaatc agatcagtct tttgtatttc ttgttttttt
     1081 gaacaactag ttaagaaaag aactaacact agacccataa ctaaagcaat gagtttattt
     1141 accaatttgt aatggtattg tcccaagtaa aaccacctcc aggtacagga attgtaactg
     1201 gtcctgcatt tgcacttatt acagttgggt agttatacca aggattccac acatagtaag
     1261 tttgataacc accttgattg acccacccaa ataatgcaag tgcatgacgg ctgttactat
     1321 aatttccata accagcagtt cccatataaa tggcatttcc ttttcttagt tgtgtttgga
     1381 cctctgaaag gtttagtatt cgtgctattt ttttaggata aacaccacag taatttgcat
     1441 attttattat ttgatcttga ttaagacttt ttgattcaat ttgactgttg tttaaattag
     1501 gataggtata atgcataatg gctctagctg aagtagcacg tacatctgtt ttgttacata
     1561 agatagcagc ttctacgtaa gcagcgcacc acggaaaact tgtttgggtt tctgctatac
     1621 gccaattaat cataataaag ttatctccgg aggagacact ttttacacgt ttaacagaat
     1681 taggcagaag tcgcccatcc tctataggtg ggtgatgaat gccgttcggt atgagggtta
     1741 ccgttggtaa ctcgaagacc gacaactaag gcgtattgcc tttttatttt gttccatgtt
     1801 acaatcagtc tatacaagaa atgagttgat ataacatgga attagataca aataatcatt
     1861 cagtatttct tctttattac caccttgttt tagtaacgaa atatcgtaga caagtgattg
     1921 atgatgaaat atctgattat gccaaaacta cttttgaaag aatttcagaa tcgtatcaca
     1981 ttactttagt ggagtggaat catgataaag accacgttca tattatgttc aaagctcaac
     2041 ctaaaacaga attgacaaaa ttcatcaatg cctataaaag tgccagctca agattgataa
     2101 aacgtgactt tccaagagtc aaacaatttc tttggaaaga aatgttctgg tctaaaagtt
     2161 tttgtcttct gacaactggt ggcgcaccaa ttgatgtgat taagaagtat atccaaaatc
     2221 aaggaaacaa tcataaatag aaagtaggtg aactttatgg aacaactaaa agcatacaaa
     2281 ttcagaatct atccaacaga ggaacaagaa atcttctttg ccaaatcttt tggttgtgtc
     2341 cgtaaggtct acaatctaat gcttgatgac cgaaaaaagg cgtatgaaga agttaaaaat
     2401 gattcttcta aaaaaatgac ttttccgaca ccagctaaat acaagaaaga atttccgttt
     2461 ttgaaagaaa ttgatagcct tgctttagcc aatgcccaac ttaatttaga taaagcatac
     2521 aagaattttt ttcgggataa atccgttgga tttccacgtt tcaaaagtaa gaaaaatcct
     2581 gttcagagtt atacaacgaa taatcaaaat ggtacagttg ctttgattga tagtaaattc
     2641 atcaaagttc ctaaattgaa gtcattagta agaattaagc ttcatagaca accaaaaggg
     2701 attatcaaat ctgctacaat atcacgtcat tctagcggta aatactatat ttctttgttg
     2761 tgtaaagaag aaattatcga attacctaaa actaattcca caattggtat tgacttaggt
     2821 attatggact ttgcgattct ttctgatgga caaaaaattg ataataataa attcacgtcc
     2881 aaaatggaaa agaaactaaa gcgtgaacaa cgcaaattgt ctaggcgtgc tttattggct
     2941 aaaaataaag gtaccaatct atttgaagct aaaaattatc aaaaacaaaa acgcaaagta
     3001 gctagattgc atgaaaaagt aatgaatcaa cgtactgatt ttctgaataa gttgagtaca
     3061 gaaatgatca aaaatcacga tattatctgt attgaagact taaacacaaa aggtatgttg
     3121 cgaaatcata aattagctaa aagtatttct gatgtttctt ggtcaaagtt tgtgactaaa
     3181 ttacaataca aggctgactg gtatggacga aaaatcatca aagtagataa atggtttccg
     3241 tctagtcaga tttgttcaga gtgcggacat aaagatggca agaaatctct tgaaattcga
     3301 gaatggactt gtcctgtttg tcatactcat catgatcgtg atatcaatgc tagtatcaat
     3361 attctgaccg aaggtctaag actacattct atgggattgg cttagatcca atcatcaaga
     3421 accgtaggaa ctacggggat agcttggtaa ataagagaca ccgctgttag taaagaaata
     3481 cgctatcaag tatgctctat tcccaagaag ctcccacttc aagcgttaag aaccgtcagg
     3541 tttagctaag tggtgagtag ttcacccgca ggaaaatttt gttttttaga aaaattttta
     3601 attttatttt ttatatttac ggatataaga tcattttttt ctgtaaggga agaaacacca
     3661 tttttttctg tacttaaagg tgatttccaa agtagtttaa tttgtccatt atcggaataa
     3721 taaatgctat tatcttgaaa aaataaggtt gtatctgtta tattactatc tactagattt
     3781 tgaagttctt ttgctaaaaa ttgtgaaata cttcctgaat attctccatt tgtatttttt
     3841 ttgacggtat aaatatattt aatcgtatta tcagcgtctg aaaatactgg aaagaaaata
     3901 gaactatttg ccgtattttc tccatcgagc attttaaatg gcgaaccaag agtatagtta
     3961 atatcagttt cggtgttatt ttccattaaa agaattgaag ttatggagtg ttcaaaatca
     4021 gttttcgcaa aattaattgc ttgttcttca attggttggg agttgatatt gaaattagaa
     4081 ttttctgaag cataggtatt tgtaattcct atactaaaaa ttccaatcat caaggaaaag
     4141 aggagaccta gataaatttt ctttttgggt ttcaaaataa tcacgccttt gtgttaaatt
     4201 taagtggtat acacctataa ttaaaatata caatatgcga taacaaattt ttgttatagt
     4261 tcataaaata ttgttttggg aacataatcg ttatttatag cgttagttaa cataatgtcg
     4321 actatgccaa gtagcccctg taccaaccga tccagccgct cactttgtga tttttcattg
     4381 gtctagctaa aaggtacgtt cggaagcttg attttccgct attgtctgtt tacgattctt
     4441 tgtgaatctt aaccgattcc tttttagaaa cttgttattt ttcataaaat atggtaaatt
     4501 tttggcagcg cttcataagc gcgctgcttt ttcaagaata aacgctcatt attttttatt
     4561 ggctgctcgt tagagcagtc tttttttatt tcagagtacg ttctattttt ttgagttacc
     4621 acgctattaa ataaccgata tttggagatt ggggcagcgc cccaaaatgc aaaaagaagg
     4681 attcgcacaa gcggattttt ctttttttgt gcaagttacc ggtaacttgc aaatcttgct
     4741 ggaagactgc cccctaaaaa agaaactgag aaatagaaaa aattttcggt ttctttttca
     4801 tctttttaga aagtttgttg ggtcaaaatt tctagaagtg aatgtttgat tggtttcttt
     4861 ttgacgattt ttgggttgat ttcgtcggga gggattgagt tgattttcaa ttttttcttt
     4921 cacttcttga tatactttag aatttgtacc gataagaaca ccagtatctt ttagatataa
     4981 atcagcaaat tctgcaatga tttcggacat aatagaaatt tcttttccca tcgcatttag
     5041 ttttgcttgg ttgctggtag ttgtcgtatt agtattaggt tcataactca tacatagaaa
     5101 acgaatggct tccgagtagt tattgatatc tggatttttt tcgatgatgg aatctaaaac
     5161 gtcaatgtga ctgggataaa gggtaacgtg tttttgaaca gaagtttttc tcatgttata
     5221 ttcctccgat aagtgtttca atgagttggt tgtttgtatg aacatagtcg ttcaatgttt
     5281 cagtattttt tgcttgtata tcgataaatt tttcgagtaa taaatcgaat tgatcttttt
     5341 tgtaatgcct aagtgcctgg tcaaaatcgt tttcgattag aacttttagg tacgcattac
     5401 ggctccattt tttgccagtt tttgttgtga gttcttggca acgtctatct atttctgaaa
     5461 taacttttgg atcaatattc cgaactaaaa tgtccataga agaattcctt tcgcatttgt
     5521 gtataattta tgtatatcat acaaatatag tatttgtata gctgtttttt gccgaaacac
     5581 tatacataag ctatccacaa tgacgaaaaa gtgatagcaa atttttttct tagaaacgtg
     5641 gtaggcacag cctacctagc acctttcgta agaaagtgat accgcgtttc cttatgctct
     5701 ttaaaaaata gcgacgtgag atcatgtcgc tatgcttgta aaagcaaaaa aagaaagtaa
     5761 cccaacaatt tttatgaata aaaattgttg ggttattgcc agaattgcca ccattttttc
     5821 tccttgtttt gtcctttttg agtttcttca gtaacagaaa ggggttcttt ttctgaagat
     5881 tcttctgcat aggttagctg gagttgttcg tgaagttttt tgatttgttg attggcttgt
     5941 agggtgagtt gttgttgctg gtcgagtaat ttttgctgcg tttctaaagc tatttgaagt
     6001 ttttcaattt gcctatcttt ttcttcaata tgattattct tagtttcaat ctccttgagt
     6061 aggtaatcgg taggtaatga atcgggtaat tcactaggta agttacccga ttcattacct
     6121 gataaaacct ttgtaattgt tgttactgct tcttttttca ggtaggtaat atttcctttt
     6181 ttgtaggtaa aattactagg taatttcctc agttgatact tcactttatc ttttgaaaca
     6241 cctagaatat ctgctaattc tttgatagtt ttatctgtca taaaaacccc ttattcttta
     6301 aataagtttt ggagattatc tagtaagttt tctttaaatt ctggggtaat atcggaattg
     6361 ttatctgcta tttgtttgtt aattttctta cttggggtat tttgttttct ttctaattct
     6421 gctaactgtt gtaaaagttc taattttcgt ttttgttctt tgattttttc ttgtaatgaa
     6481 gtaggttctt tttcagattg aacctgttga ttagctagtt ccaaagcttt attttgttct
     6541 tctttggttg gagcatgttt gttaaagtcg tctgattttt ttatctcagg tttaaatgta
     6601 aattgatagc caatgacagg ctttccccgt ccttttccgt atctcttttg gattgtcaaa
     6661 cctttgaaga ttgcggttag ttcttggcga ataggcttta taattttttt atttatatca
     6721 ctttctctat aacttttagg gatatcaagt aattcatgaa agtcttcttt tgaaaaattg
     6781 gcaattcctt tggttctgta ttgttttaat aatctaaaca tggttttgga ataactgctt
     6841 tctaattcat tgaattgttg gagagaatat cgaacccatt cttcaagatt attaagtaag
     6901 ggtaaggctt tctcatggac ttgtatttca gcaaaaggaa tatcagcttt tccatcgatt
     6961 ttaaattgat taaataaaac aaatcgttca cgttgcaaac cgtcagcact tcttctacca
     7021 aaacgtaaat ccattaattt gtcatacgtt gtttctaaat catctatgaa tcgaacattt
     7081 gcagttgctt tataattgct taaatctttt aattgttcga atgtaaattg tactttttta
     7141 tcgcctacat cacgcattct agatattata gagaagaata aattcatttc tactgacgta
     7201 aatttgcgta aaggaatcgt atttaattca tggtggtatt tcacaatttc atttgccata
     7261 aaatcctcct tcaagattaa ctacttaaca aaattataaa gagctttcta atgggggtca
     7321 accccctaat taaagacccc taaaaacaga caaaaagacc cctaaaaaca gacaaaaaga
     7381 cccctaaaaa cagacaaaaa gacccctaaa aacagacaaa aagaccccta aaagattctg
     7441 cacaccttgg gagagtaagg atacagccga cggtaaagag gtttaaaaag aggttataaa
     7501 agagattata aaagaggggg gcaaaatttc ccgcctaaaa ttttcctact ttttttctcc
     7561 aaacaggttc gcgaaatttc ctaaactggg aatctgctcc ctacggtcgc tttaaaggtg
     7621 tgatcgctac gctctcacat taaactgcgc agtcgcctaa aggctccttt
//
