LOCUS       NZ_OR797033             8274 bp    DNA     circular CON 11-DEC-2023
DEFINITION  Salmonella enterica subsp. enterica serovar Panama strain Pan86
            plasmid pPan86, complete sequence.
ACCESSION   NZ_OR797033
VERSION     NZ_OR797033.1
DBLINK      BioProject: PRJNA224116
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Panama
  ORGANISM  Salmonella enterica subsp. enterica serovar Panama
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8274)
  AUTHORS   Weill,F.-X., Pardos De La Gandara,M., Njamkepo,E., Ravel,M. and
            Guibert,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-NOV-2023) Institut Pasteur, Universite Paris Cite,
            Unite des Bacteries pathogenes enteriques, Centre National de
            Reference des Escherichia coli, Shigella et Salmonella, Institut
            Pasteur, 28 rue du Dr Roux, Parie 75724, France
COMMENT     ##Assembly-Data-START##
            Assembly Method              :: Unicycler v. 0.4.8
            Sequencing Technology        :: MinION Mk1C
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Date              :: 12/11/2023 11:23:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.6
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 9
            CDSs (total)                 :: 9
            Genes (coding)               :: 9
            CDSs (with protein)          :: 9
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OR797033.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8274
                     /organism="Salmonella enterica subsp. enterica serovar
                     Panama"
                     /mol_type="genomic DNA"
                     /strain="Pan86"
                     /serovar="Panama"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:29472"
                     /plasmid="pPan86"
                     /geo_loc_name="France"
                     /collection_date="1966"
     gene            join(7725..8274,1..311)
                     /locus_tag="U1411_RS00005"
     CDS             join(7725..8274,1..311)
                     /locus_tag="U1411_RS00005"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            complement(450..599)
                     /locus_tag="U1411_RS00010"
                     /old_locus_tag="pPan86__00002"
     CDS             complement(450..599)
                     /locus_tag="U1411_RS00010"
                     /old_locus_tag="pPan86__00002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_001677812.1"
                     /translation="MNKQQQAVLNMAGFIKSQSLTLLEKLDALDADEQAAMCEKLHELA
                     EEGV"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            884..1207
                     /gene="mobA"
                     /locus_tag="U1411_RS00015"
                     /old_locus_tag="pPan86__00003"
     CDS             884..1207
                     /gene="mobA"
                     /locus_tag="U1411_RS00015"
                     /old_locus_tag="pPan86__00003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052604.1"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization protein MobA"
                     /protein_id="WP_000166966.1"
                     /translation="MTKRSGSNTRRRAISRPVRLTAEEDQEIRKRAAECGKTVSGFLRA
                     AALGKKVNSLTDDRVLKEVMRLGALQKKLFIDGKRVGDREYAEVLIAITEYHRALLSRL
                     MAD"
                     /name="mobA"
     gene            complement(1442..1822)
                     /gene="lsoB"
                     /locus_tag="U1411_RS00020"
                     /old_locus_tag="pPan86__00004"
     CDS             complement(1442..1822)
                     /gene="lsoB"
                     /locus_tag="U1411_RS00020"
                     /old_locus_tag="pPan86__00004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin LsoB"
                     /protein_id="WP_000710826.1"
                     /translation="MKKDKKYQIEAIKNKDKTLFIVYATDIYSPSEFFSKIESDLKKKK
                     SKGDVFFDLIIPNGGKKDRYVYTSFNGEKFSSYTLNKVTKTDEYNDLSELSASFFKKNF
                     DKINVNLLSKATSFALKKGIPI"
                     /name="lsoB"
     gene            complement(1819..2859)
                     /gene="lsoA"
                     /locus_tag="U1411_RS00025"
                     /old_locus_tag="pPan86__00005"
     CDS             complement(1819..2859)
                     /gene="lsoA"
                     /locus_tag="U1411_RS00025"
                     /old_locus_tag="pPan86__00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA
                     endoribonuclease LsoA"
                     /protein_id="WP_000068433.1"
                     /translation="MAQNPFKALNINIDKIESALTQNGVTNYSSNVKNERETHISGTYK
                     GIDFLIKLMPSGGNTTIGRASGQNNTYFDEIALIIKENCLYSDTKNFEYTIPKFSDDDR
                     ANLFEFLSEEGITITEDNNNDPNCKHQYIMTTSNGDRVRAKIYKRGSIQFQGKYLQIAS
                     LINDFMCSILNMKEIVEQKNKEFNVDIKKETIESELHSKLPKSIDKIHEDIKKQLSCSL
                     IMKKIDVEMEDYSTYCFSALRAIEGFIYQILNDVCNPSSSKNLGEYFTENKPKYIIREI
                     HQETINGEIAEVLCECYTYWHENRHGLFHMKPGIADTKTINKLESIAIIDTVCQLIDGG
                     VARLKL"
                     /name="lsoA"
     gene            complement(3124..3237)
                     /locus_tag="U1411_RS00030"
     CDS             complement(3124..3237)
                     /locus_tag="U1411_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001459398.1"
                     /translation="MHEPPVQPDRCALSGNYRLESNPVRHDLSPLAAAIGN"
                     /name="hypothetical protein"
     gene            3441..3596
                     /locus_tag="U1411_RS00035"
     CDS             3441..3596
                     /locus_tag="U1411_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001490772.1"
                     /translation="MSVDFCDARQGGGAYGKTPAALASSGALLFAHMFFPALSPDSVDN
                     RITAFE"
                     /name="hypothetical protein"
     gene            complement(3816..6821)
                     /locus_tag="U1411_RS00040"
                     /old_locus_tag="pPan86__00006"
     CDS             complement(3816..6821)
                     /locus_tag="U1411_RS00040"
                     /old_locus_tag="pPan86__00006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143760.1"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGTLGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            6985..7542
                     /locus_tag="U1411_RS00045"
                     /old_locus_tag="pPan86__00007"
     CDS             6985..7542
                     /locus_tag="U1411_RS00045"
                     /old_locus_tag="pPan86__00007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001235713.1"
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     ARG             7726..8273
                     /name="TEM-163"
                     /gene="TEM-163"
                     /gene_name="TEM beta-lactamase"
                     /tool="rgi"
                     /drug_class="monobactam; cephalosporin; penam; penem"
                     /identity="100.0"
                     /coverage="63.99"
     ARG             4..311
                     /name="TEM-185"
                     /gene="TEM-185"
                     /gene_name="TEM beta-lactamase"
                     /tool="rgi"
                     /drug_class="monobactam; cephalosporin; penam; penem"
                     /identity="100.0"
                     /coverage="35.66"
     Typing          635..875
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.12e-123"
     Typing          complement(3166..3695)
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.972"
                     /coverage="97.0"
                     /evalue="0.0"
     Typing          885..1204
                     /name="MOBF"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.065"
                     /coverage="100.0"
                     /evalue="2.19e-62"
ORIGIN
        1 tggcaacaac gttgcgcaaa ctattaactg gcgaactact tactctagct tcccggcaac
       61 aattaataga ctggatggag gcggataaag ttgcaggacc acttctgcgc tcggcccttc
      121 cggctggctg gtttattgct gataaatctg gagccggtga gcgtgggtct cgcggtatca
      181 ttgcagcact ggggccagat ggtaagccct cccgtatcgt agttatctac acgacgggga
      241 gtcaggcaac tatggatgaa cgaaatagac agatcgctga gataggtgcc tcactgatta
      301 agcattggta actgtcagac caagtttact catatatact ttagattgat ttaaaacttc
      361 atttttaatt taaaaggatc taggtgaaga tcctttttga taatctcatg accaaaatcc
      421 cttaacgtga gttttcgttc cactgagcgt cagacccctt cttctgcgag ttcgtgcagc
      481 ttctcacaca tggcagcctg ttcgtcagca tcgagtgcgt ccagcttttc gagcagcgtc
      541 aggctctggc tttttatgaa tcctgccatg ttgagtacag cttgctgctg cttgttcatc
      601 ttttcgtttt ctccgttctg tctgtcatct gcgttgtgtg attatatcgc gtaccacttt
      661 tcgactgttt taccgccggt attctgccgt ctgacgcttt gacgggtatt tctgcctgac
      721 aatactgtca ctgccaaaaa actgccgtgc ctttgtcggt aattcgagct tgctgacagg
      781 acaggatgtg caattgttat accgcgcata catgcacgct attacaatta ccctggtcag
      841 ggcttcgccc cgacacccca tgtcagatac ggagccatgt tttatgacaa aacgaagtgg
      901 aagtaatacg cgcaggcggg ctatcagtcg ccctgttcgt ctgacggcag aagaagacca
      961 ggaaatcaga aaaagggctg ctgaatgcgg caagaccgtt tctggttttt tacgggcggc
     1021 agctctcggt aagaaagtta actcactgac tgatgaccgg gtgctgaaag aagttatgcg
     1081 actgggggcg ttgcagaaaa aactctttat cgacggcaag cgtgtcgggg acagagagta
     1141 tgcggaggtg ctgatcgcta ttacggagta tcaccgtgcc ctgttatcca ggcttatggc
     1201 agattaactt cccggagaga aactgtcgaa aacagacggt atgaacgccg taagccccca
     1261 aaccgatcgc cattcacttt catgcatagc tatgcagtga gctgaaagcg atcctgacgc
     1321 atttttccgg tttaccccgg ggaaaacatc tctttttgcg gtgtctgcgt cagaatcgcg
     1381 ttcagcgcgt tttggcggtg cgcgtaatga gacgttatgg taaatgtctt ctggcttgat
     1441 attatattgg aatgcctttt ttcaaagcaa atgatgtggc tttggataga aggtttacgt
     1501 tgatcttatc aaagtttttt ttaaagaacg aagccgagag ctcagataaa tcattatatt
     1561 catcagtttt cgtaactttg tttaatgtgt aacttgaaaa cttctcgcca ttaaatgacg
     1621 tatagacgta acgatctttt tttccaccgt taggaattat taaatcaaaa aaaacatcac
     1681 ccttgctttt ctttttcttc aagtcggatt cgatttttga gaaaaattcg ctcgggctat
     1741 aaatatcagt agcatagaca ataaataaag ttttatcttt attttttatt gcttctattt
     1801 gatatttttt atcttttttc ataatttcaa cctagctacg ccaccatcta ttaattggca
     1861 aacggtatcg atgattgcga ttgattctaa tttgttaatt gtcttcgtgt cagctattcc
     1921 tggtttcata tgaaacaaac catgcctgtt ctcatgccag taagtgtagc attcacacaa
     1981 aacttccgct atttcaccat ttatagtttc ttggtgtatt tctctgatta tatatttggg
     2041 tttgttttca gtgaagtatt cgccaaggtt ctttgatgat gatggattgc aaacatcatt
     2101 aagtatttga tatataaagc cttctatggc tcttaatgca gagaagcagt atgttgagta
     2161 atcttccatt tcgacatcta tttttttcat tattagcgag catgatagct gttttttgat
     2221 atcttcatgg attttatcga tgctttttgg tagtttgcta tgcaactcgg actcaatagt
     2281 ttcttttttt atgtcaacat taaattcttt atttttttgt tcgacaatct ctttcatgtt
     2341 tagtattgag cacatgaaat cgttaatcaa actcgcgatt tgaaggtatt ttccttggaa
     2401 ttgaatagag ccgcgcttgt aaatttttgc cctgaccctg tcaccattgc tggtggtcat
     2461 aatatattgg tgtttacaat taggatcgtt attattatct tctgttattg ttatcccctc
     2521 ttcagaaaga aattcaaata gatttgccct gtcatcatca ctgaattttg gaatggtgta
     2581 ttcaaagttc tttgtgtctg aatacaaaca gttttctttt ataatcaagg cgatttcatc
     2641 aaagtaagtg ttattttgcc cagacgctct tccgatagtg gtatttccgc ctgatggcat
     2701 tagttttatt aagaagtcta ttcctttata tgtgccagat atgtgagttt ctctttcgtt
     2761 ttttacatta gaggaatagt ttgtgacgcc attctgcgtc agagcagact caatcttgtc
     2821 aatattgata tttagtgctt taaacgggtt ctgtgccatt gggtcaatcc gttgtttttt
     2881 ttgaatatgt acagatcttg tttttttgtc aacggaatag ctgttcgttg acttgataga
     2941 ccgattgatt catcatctca taaataaaga aaaaccaccg ctaccaacgg tggttttctc
     3001 aaggttcgct gagctaccaa ctctttgaac caaggtaact ggcttggagg agcgcagtca
     3061 ccaaaatctg ttctttcagt ttagccttaa caggtgcata acttcaagac aaactcctct
     3121 aaatcagtta ccaatggctg ctgccagtgg cgataagtcg tgtcttaccg ggttggactc
     3181 aagacgatag ttaccggata aggcgcagcg gtcgggctga acggggggtt cgtgcacaca
     3241 gcccagcttg gagcgaacga cctacaccga actgagatac caacagcgtg agctatgaga
     3301 aagcgccacg cttcccgaag ggagaaaggc ggacaggtat ccggtaagcg gcagggtcgg
     3361 aacaggagag cgcacgaggg agcttccagg gggaaacgcc tggtatcttt atagtcctgt
     3421 cgggtttcgc cacctctggc ttgagcgtcg atttttgtga tgctcgtcag gggggcggag
     3481 cctatggaaa aacgcctgcg gcgttggctt cttccggtgc tttgcttttt gctcacatgt
     3541 tctttccggc tttatcccct gattctgtgg ataaccgtat taccgctttt gagtgagctg
     3601 acaccgctcg ccgcagtcga acgaccgagc gtagcgagtc agtgagcgag gaagcggaag
     3661 agcgccttat gtgacatttt ctccttacgc tctgttgtgc cgttcggcat cctgtcctga
     3721 gagttatctc tctgtgctat tttctacttc aaagcgtgtc tggatgctgt tctggagttc
     3781 ttggggtctg acgctcagtg gaacgaaaac tcacgttaag caacgttttc tgcctctgac
     3841 gcctctttta atggtctcag atgtcctttg gtcaccagtt ctgccagcgt gaaggaataa
     3901 tggccgagca tattgatatg tccgtggcaa agcggggaga ggcgtgcgat atcttcatca
     3961 ttcagtgttt caccctgcgc ccggagatga tccagggctg cctgcatata aatagtgttc
     4021 cataacacga cggcgttagt gaccagcccc agtgtgccca gttgatcttc ctgaccgtcg
     4081 gtatatcgtt ttcttatctc acctttttga ccgtgacaga tggctctggc aacggcatgg
     4141 cgactttctc cccgattaag ctgggtcaga atgcgccggc ggtaatcttc atcatcaata
     4201 taattaagca gatacagcgt tttgttgatg cgccccactt caatgattgc ctgagtcagt
     4261 ccggaaggac gttcactttt cagcaatgaa cggaccagca ctgaaacctg tactttgccc
     4321 agcttcaggg agccagcggt ccggatcatt tcgtcccact gaaggactat ttttcgggga
     4381 tctgattgcc ctctggcaat atcattcagc acgccatagt cggcatcatg gtccattcgc
     4441 cagaaaaccg aagcaccggc atcagccagg cgtggagaaa actggtatcc cagcagccag
     4501 aaaaggccaa agacaagttc gctggcacct gctgtatcgg tcataatttc ggttggattc
     4561 agcccggtct cctgttccag aagaccttcc agcacaaaga tagagtccct cagcgtcccc
     4621 ggtataacga tgccatgaaa gccggaatac tgatcggaca caaagttgta ccaggtgatc
     4681 cctctgttat taccaaagta tttgcggttc ggtccggcat tgattgttct gactggcgta
     4741 acaaagcgca ttccatctgc agatgccact tctcctccac cccatatctg tgccagtggc
     4801 agcgttgcct gaaaatcaac cagtctggca ttagcgctgg tgatagtttc agcccgcaga
     4861 tagttcgctt ttgtccagtt cagccggtgt cgggtcagtg caggaacatt tgatctgatc
     4921 agtggttcca gaccgatatt gcaggcttca gccatcagca cggcgctgat gctgacgggc
     4981 agatcatcaa ctctggcact ggcttcacta gcatggaaaa actcatcagc aaatccggta
     5041 tgggcgttaa tttcgagcag caactccgtt aaatccaccg gagggagtag atcactgatc
     5101 attttgctca gtcgtttcag actgtccggc tcatcaagac tggcgagggg agaaattgtc
     5161 aaccggggct tcgggccaga aacatcgagt tcgacagcct cattttcgca aagacgtgca
     5221 gcaacctgtc tgtaacgact atcaagctga tgacccagag attttattgc ttcctgcggg
     5281 tctgtcgggt gccccaaaga acgataaacc ttaatccggt ttgcctgcca gtcagcaccc
     5341 tgtagtaatc ttgcacgagg atctccccac cggttactgc cggtaacgta gacatccctc
     5401 cgcctcagac tatcctgcag tttactgaga aagcagagcg tgtatcccct gcgggtgata
     5461 tgtttttcct tgttaatcac cagccgtttc catgaccgac tgataatttc cgttggtgcg
     5521 tcgtcaaaaa actgccgccg tgagctgaac tcccggctga ggtagtcaca ggcattcaga
     5581 gtggtaaccc cggcaggtgc ggatgaaaat ttaacggtat tcagcagatg gggcaggaaa
     5641 cgacgaacgc gcccgtactg ctccaccatt tcttcatgaa aattatcgtc tgagggccgg
     5701 gcaatttcac ggacaagcgt gatgatttca gccagctttt gccttgggat gtagctgaac
     5761 acctcagcac gaatcgattc gtccggtgtt tcttctttca gcaggtacga acatgcgctg
     5821 gcgagcgcca atgcagattt atccagatcc ttcagcgagc ggagccgttt tttctgccca
     5881 atctttctgg cgtcacggat gataacggcc agcatggcgt ccagaacgtc caatgcatca
     5941 tccagcgcca gcgtttccca tgcaaggaca aaggcaacca gaaccgccat ccttttctgc
     6001 ggtgacatcc tggcaatatt gaacaccgaa gtcataccag cataacgtgc gagatttttc
     6061 aggcgcacag ccgggagtgt actcaggttt tcagcatgca ggccaaaatc gttcagagtt
     6121 ttccagcgtt caattgcttc attaaacgcc ggaccactga tggtcacagg gccctttttc
     6181 agtgattcca gtaaagacag gcggctgcaa tcagttggcc ccagcagcat ctccagctgt
     6241 gaacgctgtt cggctgacgg tatcagtgcc agtttgttcc acaggcgcaa cgtcgccttt
     6301 tcccttacct ctgaaatcaa ccgggtcagc gtagtggctc cggggagaat aatacgatgt
     6361 tgcataagcc accctgtcgc cagatcgaaa agcaggccag gacgttcgtt gcttatccag
     6421 ctccgggtat ataaaagacg ggtaaggcga aatgtccagg gccaggcaaa ttcacgatac
     6481 tgatagtgct gacgtatcag cgctgcatgc tcacggcggg tattttccct ctgaccgtat
     6541 tctgcaagaa cggtgatatc acgaatcccg agctgtctgg cggtaaaatg ccggacgccg
     6601 gaaggaatat gattcatatc ggtgaggaag gtgcccagaa aacggacaca tccaatttgc
     6661 agggcaatgc ccagacggtt gtgatcacct ctgctttttc cgataaattc cttgtctgct
     6721 tcatcaaggt gaaaatatcg tgccagctga agctcatccg gttcaccggt gaatctgcca
     6781 tagctttcag tctgctcagt ggtcagaaag tcaacgggca tatcggcctc cctgcctgac
     6841 gggcatttag taacattttt ccaaccgtac gaaatgttat aaattatcgg acatcgtaaa
     6901 actgttacat taatatgtct attaaatcgt aaatttgtaa taatagacat gagttgtccg
     6961 atattcgatt taaggtacat ttttatgcga ctttttggtt acgctcgggt ctcaaccagt
     7021 cagcagtctc ttgatcttca ggtcagagca ctcaaagacg caggtgtgaa agcaaaccgt
     7081 atatttaccg ataaggcatc cggcagttca acagaccggg aagggctgga tttgctgagg
     7141 atgaaggtgg aggaaggtga tgtcattctg gttaagaagc tcgaccgtct tggccgcgac
     7201 actgccgata tgatccaact gataaaggaa tttgacgctc agggcgtggc agtccggttc
     7261 attgatgacg ggatcagtac cgacggtgat atggggcaaa tggtggtcac catcctgtcg
     7321 gctgtggcac aggctgaacg ccggaggatc ctagaacgca cgaatgaggg ccgacaggaa
     7381 gcaaagctga aaggaatcaa atttggccgc aggcgtaccg tggacaggaa cgtcgtgctg
     7441 acgcttcatc agaagggcac tggtgcaacg gaaattgctc atcagctcag tattgcccgc
     7501 tccacggttt ataaaattct tgaagacgaa agggcctcgt gatacgccta tttttatagg
     7561 ttaatgtcat gataataatg gtttcttaga cgtcaggtgg cacttttcgg ggaaatgtgc
     7621 gcggaacccc tatttgttta tttttctaaa tacattcaaa tatgtatccg ctcatgagac
     7681 aataaccctg gtaaatgctt caataatatt gaaaaaggaa gagtatgagt attcaacatt
     7741 ttcgtgtcgc ccttattccc ttttttgcgg cattttgcct tcctgttttt gctcacccag
     7801 aaacgctggt gaaagtaaaa gatgctgaag atcagttggg tgcacgagtg ggttacatcg
     7861 aactggatct caacagcggt aagatccttg agagttttcg ccccgaagaa cgttttccaa
     7921 tgatgagcac ttttaaagtt ctgctatgtg gtgcggtatt atcccgtgtt gacgccgggc
     7981 aagagcaact cggtcgccgc atacactatt ctcagaatga cttggttgag tactcaccag
     8041 tcacagaaaa gcatcttacg gatggcatga cagtaagaga attatgcagt gctgccataa
     8101 ccatgagtga taacactgct gccaacttac ttctgacaac gatcggagga ccgaaggagc
     8161 taaccgcttt tttgcacaac atgggggatc atgtaactcg ccttgatcgt tgggaaccgg
     8221 agctgaatga agccatacca aacgacgagc gtgacaccac gatgcctgca gcaa
//
