LOCUS       NZ_OR095742            19351 bp    DNA     circular CON 11-SEP-2023
DEFINITION  Klebsiella pneumoniae isolate R10-KP plasmid pR1041-kp1-20k,
            complete sequence.
ACCESSION   NZ_OR095742
VERSION     NZ_OR095742.1
DBLINK      BioProject: PRJNA224116
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 19351)
  AUTHORS   Ye,L.
  TITLE     R10.4.1-plasmids sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19351)
  AUTHORS   Ye,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUN-2023) ABCT, PolyU, hung hom, hongkong, hongkong
            518000, China
COMMENT     ##Assembly-Data-START##
            Assembly Method              :: Flye v. 2.9.2
            Sequencing Technology        :: nanopore
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Date              :: 09/11/2023 07:10:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.6
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 26
            CDSs (total)                 :: 26
            Genes (coding)               :: 26
            CDSs (with protein)          :: 26
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            OR095742.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19351
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /isolate="R10-KP"
                     /isolation_source="hospital"
                     /db_xref="taxon:573"
                     /plasmid="pR1041-kp1-20k"
                     /geo_loc_name="China"
     gene            complement(836..985)
                     /locus_tag="RI157_RS00005"
                     /old_locus_tag="JGJGGADC_00001"
     CDS             complement(836..985)
                     /locus_tag="RI157_RS00005"
                     /old_locus_tag="JGJGGADC_00001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(1070..1327)
                     /locus_tag="RI157_RS00010"
                     /old_locus_tag="JGJGGADC_00002"
     CDS             complement(1070..1327)
                     /locus_tag="RI157_RS00010"
                     /old_locus_tag="JGJGGADC_00002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            complement(1337..3022)
                     /locus_tag="RI157_RS00015"
                     /old_locus_tag="JGJGGADC_00003"
     CDS             complement(1337..3022)
                     /locus_tag="RI157_RS00015"
                     /old_locus_tag="JGJGGADC_00003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            3349..3594
                     /locus_tag="RI157_RS00020"
                     /old_locus_tag="JGJGGADC_00004"
     CDS             3349..3594
                     /locus_tag="RI157_RS00020"
                     /old_locus_tag="JGJGGADC_00004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            3868..4239
                     /gene="tolA"
                     /locus_tag="RI157_RS00025"
                     /old_locus_tag="JGJGGADC_00005"
     CDS             3868..4239
                     /gene="tolA"
                     /locus_tag="RI157_RS00025"
                     /old_locus_tag="JGJGGADC_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            4236..4454
                     /locus_tag="RI157_RS00030"
                     /old_locus_tag="JGJGGADC_00006"
     CDS             4236..4454
                     /locus_tag="RI157_RS00030"
                     /old_locus_tag="JGJGGADC_00006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002193751.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_255087386.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFGKR"
                     /name="TonB family protein"
     gene            4775..5053
                     /locus_tag="RI157_RS00035"
                     /old_locus_tag="JGJGGADC_00007"
     CDS             4775..5053
                     /locus_tag="RI157_RS00035"
                     /old_locus_tag="JGJGGADC_00007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            5041..5355
                     /locus_tag="RI157_RS00040"
                     /old_locus_tag="JGJGGADC_00008"
     CDS             5041..5355
                     /locus_tag="RI157_RS00040"
                     /old_locus_tag="JGJGGADC_00008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            5519..5947
                     /locus_tag="RI157_RS00045"
                     /old_locus_tag="JGJGGADC_00009"
     CDS             5519..5947
                     /locus_tag="RI157_RS00045"
                     /old_locus_tag="JGJGGADC_00009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            5973..6152
                     /locus_tag="RI157_RS00050"
                     /old_locus_tag="JGJGGADC_00010"
     CDS             5973..6152
                     /locus_tag="RI157_RS00050"
                     /old_locus_tag="JGJGGADC_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(6179..6709)
                     /locus_tag="RI157_RS00055"
                     /old_locus_tag="JGJGGADC_00011"
     CDS             complement(6179..6709)
                     /locus_tag="RI157_RS00055"
                     /old_locus_tag="JGJGGADC_00011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(6716..7447)
                     /gene="mobC"
                     /locus_tag="RI157_RS00060"
                     /old_locus_tag="JGJGGADC_00012"
     CDS             complement(6716..7447)
                     /gene="mobC"
                     /locus_tag="RI157_RS00060"
                     /old_locus_tag="JGJGGADC_00012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            complement(7447..9411)
                     /locus_tag="RI157_RS00065"
                     /old_locus_tag="JGJGGADC_00013"
     CDS             complement(7447..9411)
                     /locus_tag="RI157_RS00065"
                     /old_locus_tag="JGJGGADC_00013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_071177727.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(10895..11044)
                     /locus_tag="RI157_RS00070"
                     /old_locus_tag="JGJGGADC_00014"
     CDS             complement(10895..11044)
                     /locus_tag="RI157_RS00070"
                     /old_locus_tag="JGJGGADC_00014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(11129..11386)
                     /locus_tag="RI157_RS00075"
                     /old_locus_tag="JGJGGADC_00015"
     CDS             complement(11129..11386)
                     /locus_tag="RI157_RS00075"
                     /old_locus_tag="JGJGGADC_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            complement(11396..13081)
                     /locus_tag="RI157_RS00080"
                     /old_locus_tag="JGJGGADC_00016"
     CDS             complement(11396..13081)
                     /locus_tag="RI157_RS00080"
                     /old_locus_tag="JGJGGADC_00016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            13408..13653
                     /locus_tag="RI157_RS00085"
                     /old_locus_tag="JGJGGADC_00017"
     CDS             13408..13653
                     /locus_tag="RI157_RS00085"
                     /old_locus_tag="JGJGGADC_00017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            13927..14298
                     /gene="tolA"
                     /locus_tag="RI157_RS00090"
                     /old_locus_tag="JGJGGADC_00018"
     CDS             13927..14298
                     /gene="tolA"
                     /locus_tag="RI157_RS00090"
                     /old_locus_tag="JGJGGADC_00018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            14295..14660
                     /locus_tag="RI157_RS00095"
                     /old_locus_tag="JGJGGADC_00019"
     CDS             14295..14660
                     /locus_tag="RI157_RS00095"
                     /old_locus_tag="JGJGGADC_00019"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            14835..15113
                     /locus_tag="RI157_RS00100"
                     /old_locus_tag="JGJGGADC_00020"
     CDS             14835..15113
                     /locus_tag="RI157_RS00100"
                     /old_locus_tag="JGJGGADC_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            15101..15415
                     /locus_tag="RI157_RS00105"
                     /old_locus_tag="JGJGGADC_00021"
     CDS             15101..15415
                     /locus_tag="RI157_RS00105"
                     /old_locus_tag="JGJGGADC_00021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            15579..16007
                     /locus_tag="RI157_RS00110"
                     /old_locus_tag="JGJGGADC_00022"
     CDS             15579..16007
                     /locus_tag="RI157_RS00110"
                     /old_locus_tag="JGJGGADC_00022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            16033..16212
                     /locus_tag="RI157_RS00115"
                     /old_locus_tag="JGJGGADC_00023"
     CDS             16033..16212
                     /locus_tag="RI157_RS00115"
                     /old_locus_tag="JGJGGADC_00023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(16239..16769)
                     /locus_tag="RI157_RS00120"
                     /old_locus_tag="JGJGGADC_00024"
     CDS             complement(16239..16769)
                     /locus_tag="RI157_RS00120"
                     /old_locus_tag="JGJGGADC_00024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(16776..17507)
                     /gene="mobC"
                     /locus_tag="RI157_RS00125"
                     /old_locus_tag="JGJGGADC_00025"
     CDS             complement(16776..17507)
                     /gene="mobC"
                     /locus_tag="RI157_RS00125"
                     /old_locus_tag="JGJGGADC_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            complement(17507..19228)
                     /locus_tag="RI157_RS00130"
                     /old_locus_tag="JGJGGADC_00026"
     CDS             complement(17507..19228)
                     /locus_tag="RI157_RS00130"
                     /old_locus_tag="JGJGGADC_00026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_309387713.1"
                     /translation="MSVLASLDSPGRMVRARRHVWNYAYWLTGAAGLALLGGLVVAVFI
                     ESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLVAGVLLARLLAFLLLDGHFAAAD
                     EAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNALADFSTEQARKQQAVFLGKDEQ
                     GQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRCVRDFGDAVVYFDPKGDAWAPHV
                     FRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLVAGFNLSETGDVADHYRISEQKA
                     AKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLITKLENVADLSVLQTDSGIDVAGI
                     INGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARDEFRRWPHASIMLDEIKYLLSKY
                     VLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFVKTTVLDNTPIRWFYRAASQESA
                     QWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQKEARPLFDVNTLQHLPDGFAVMT
                     GLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEYLPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     BGC             1..18081
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          155..733
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          10214..10792
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(6720..7447)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.37e-140"
     Typing          complement(16780..17507)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.37e-140"
ORIGIN
        1 catcagcgcg tccggtgacc gtcttgcagg tgccggggaa attgcgcctc ctcgctcact
       61 cggtcgctac gctccgggcg tgagactgcg gcgggcgctg cggacacata caaagttacc
      121 cacagattcc gtggataagc aggggactaa catgtgaggc aaaacggcag ggccgcgccg
      181 gtggcgtttt tccataggct ccgccctcct gccagagttc acataaacag acgctttttc
      241 ggtgcatctg tgggagccgt gaggctcaac catgaatctg acagtacggg cgaaacccga
      301 caggacttaa agatccccac cgtttccggt aggtcgctcc ctcttgcgct ctcctgttcc
      361 gaccctgccg tttaccggat acctgtccgc cgttctccct tgcgggaagt gtggcgcttt
      421 ctcatagctc acacactggt atctcggctc ggtgtaggtc gttcgctcca agctgggctg
      481 taagcaagaa ctccccgttc agcccgactg ctgcgcctta tccggtaact gttcacttga
      541 gtccaacccg ggaaagcacg caaaacgcca ctggcagcag ccattggtaa ctgggagttc
      601 gcagaggatt tgtttagcta aacacgcggt tgctcttgaa gtgtgcgcca aagtccggct
      661 acactggaag gacagatttg gttgctgtgc tctgcgaaag ccagttacca cggttaagca
      721 gttccccaac tgacttaacc ttcgatcaaa ccacctcccc aggtggtttt ttcgtttaca
      781 gggcaaaaga ttacgcgcag aaaaaaagga tctcaagaag atcctttgat cttttctact
      841 gaaccgcgat ccccgtcagt tcagaggagg acgatggtgc caccgttccg ccctgaacat
      901 cccggatata atttgcctga catgcggcca gaagaaagcc agcaacaatc aatataaaaa
      961 gaaaaatagt ctttaccttt ttcatatact ttccctgtat ttaaagactc cggcattcat
     1021 ccctgaacac cggaagtcag tatttcaaat catccttgat aattttttgt taccagttac
     1081 cgtcccgata atcaaaagct atataacaat tatccacatc aggttttatt tgatttttaa
     1141 aaaatggctg tagtaaagga acccattctt tcttcaaatc aaactcacca ttattaatat
     1201 tatcctttaa aggcattccc aagctttcaa tgacagaacc atcgtcacca aagtctttag
     1261 aatactcttc ccctttaaac tcttcagttt tcttatcaaa ccatgtcaaa cgtaatttaa
     1321 gccccatatt tacctctcaa agatattttt taatgttccg ttttggatct ggccctttaa
     1381 cctgcttacc cgttttggga tcaaatgcgc ctaggtgttc gccatcactg gcacgatacc
     1441 cttcaagctc accgtgctgg gaatcccatt cataaatttt acgtttttta tcgccatacc
     1501 atcgggcccg cttaccacca ccaccttgtt taggtgtttt aggatcacct cgctttaact
     1561 ctccaagtcc ctttatgtct tctgttttag gtactggatg ataatcatgg ccgtagtctt
     1621 tagtcccctt gcgaggcttg ttcttttcct catttaactt attttctgca tccttcgctt
     1681 ttttctcctt ttgtttccgg ctctccatcg ccccggtaag tgcagcctta tctctggata
     1741 aggattcatt cattgcgttt aaagatgcct gagccgcttt taatttctca ttctgattct
     1801 gaatatcctt atcaagatag cgaacctgat cctgccaccc ggagccatat tcatgaggcg
     1861 ggttataagt cacaaaatca tctttatttg cctctgcctc ttttaccttt ttatcggctt
     1921 cctgaacagc agcccttgca ccggggagcg ccttctctgt cgatgcaatg cggctgttta
     1981 aggtcgcaat atttttatct tcggcatcca gctcagcttt cgctttatca tagtctcttt
     2041 tcagcccctc ttccggatga gcggcgtccc atgcctgctg gcgacgcttt tcttcctcct
     2101 gacgctgttt tacctgtgcc ggggtaagaa catctgtcac cgacacataa accggcttct
     2161 gtccggtctc tttcgggaaa cgaataacgg cctcacggga gttaccaccg gctgtaaaac
     2221 cagccggacg tgaatcacct ttttcagcaa caatgccttt tggcggggct ttcgctgtcg
     2281 gaacaccttt cggtacgctc acctgcagag acgggagacc cggaatcgac acactgaata
     2341 cccccggacg ttttgtcggt ttcgcatcca ccacagggac actcattggc cgacctgcga
     2401 caaccgcaat atgctgccgc tcatccttca ccacatccac aacccgttgt ctgacacgaa
     2461 ccgtcgcctg gtccagtggt aaagtacttg ccggagtctc cgtcaccgca tcggccggta
     2521 atgacgtcat aatttttgac atcattttcg gatcatcttt tgcaatctca gaaggcagca
     2581 caccgtagat cgcaatcccc cacagaccaa acttaaacgg ccccttcagg gcagccagca
     2641 catcagcaac ggcggccgac aacgcatcgc cggaaactga taaagccagt ccttcagccc
     2701 ccggagtagc cagggcaggc agaccgaagg ccatcgcagt ggccgaagac tgtccgccac
     2761 cagagctacc gctatgattg ccgctgttac caccattacc accgggttta ctcccgccgt
     2821 taccaaactc ccccggatta tagttatgaa tatctccatt cggcgtatgc gtcgtacccc
     2881 agcccggccc gctgtttgga tccgtaccac cacctgatga agggccacct ttaccagacg
     2941 taccgttcac attcccactg gcctgaccac cattatgtcc cagacctgaa ttacccggac
     3001 ctcgaccgtc tccaccactc ataccgtttt cctctttgac atttaaaaca ataaattaaa
     3061 gccaacatac tgtacatata cacagtataa ttattacctt actcctcccg ttttcaggtg
     3121 tcaatatatg agattagttc tcatcttcag gcacaaaaaa gcgcccggag ccacctgtaa
     3181 gcagatcgcg tcttttcccg aaaatttctc atggcaacaa attttattat ttaagacatt
     3241 catcacactt acatttcaga tggtatagac acatctgaaa gctaactggc atgaggagag
     3301 gacctgcggt taaactgttc gggaaacctg agacgcccgg aggccactat gacgcacctg
     3361 aaactgactc ccgctgaaga aaagcgcctg gcggacgcct ttgtcgctca ggcactggcc
     3421 atgggcctga aagggaacaa aacgctgcca aaggcggtaa aacaacaggt gcgggaaagg
     3481 gtgcttcgtg ccattcagga cgaacgtgaa gccaggcggg cgcaggaaat gcgtcgggag
     3541 aaatacgagg ctacggaaac caccttcacc tggcagccac agcgccgccg gtaaggggta
     3601 tttaccataa cgtcgcattg cccgcaccgc tcagacggtc tgagggcgtt tccggcggct
     3661 acgggataaa acaggcaaca aaccacccgg aaaaccgccg gaaacgcgcc cggtaaattg
     3721 taacccgctg catgcctatg cacgcaactg catggcgggc cgtttggtgt aaaaacgata
     3781 cgataagccg tgtttatgta aatgaacgtg gccgtaaaga gtgacaaata tacatgtaac
     3841 attttttact gacaggtcat caacccgatg cgtttaatac cctttatcct gctggcattg
     3901 tgcagcccct tactcctgac ggcctgtaag cattccacca cccagccgcc gaaaatttat
     3961 actctggata agtcatctaa aatcagtagc tacgctgcgg ccatcaagac cgctgttgaa
     4021 atgcagatgt ttgaaccaga ggcctatgcg ggaaaaatgt gcaccgtgcg gatatccata
     4081 caacgtgatg gcactctgaa cagcgccatt gctgaaggag gagatccgaa actctgtaaa
     4141 gcagcaatat cagccgttac ccacgccaaa attccgccgg caccggatga aaatacctgg
     4201 caaatattca aaaacgcccc tctggatttc agaccatgaa agcttttact ctgacagtgc
     4261 tggcggccat gttcctcact ccggtacatg cgataccact aaaacccgta accacactgc
     4321 agccaaccta cccggtacag gccgcagcaa aacgcatcga aggtcaggtg accgccacgt
     4381 ttgatattct ggacgatgga cgagtggaca acgtgtcgct taccggctgt cacctttttt
     4441 tcgggaaacg ctgacggcaa tgaggcactg gctatatccc gcagggcacc cggcaatgcg
     4501 acaggttata aattttgaat tcagtctgaa aaatgacggc ttacaggatc cgcgaccagt
     4561 caccacccaa aagctcaatg atgatggttg ccgccagtaa caggtccttt aacccgcagg
     4621 ctgcaatagt cctggatgat gagtgagcct gtagcagccc tgattagtgg aagcgaagct
     4681 gaaaaatggg cagcaaaagc cgtatttctg gcaaatagcg ccgccacgga ttaaagtagt
     4741 catgtgtaat acatatgact acaaaggggc ttttatgtca tcagcaacat ccatcaggct
     4801 cgatgaagaa cttaaggacc ggctgaaaac gctggccgat gaccggcacc gctcagcgca
     4861 cgcgctaatg ctggaggcaa tcaccgaata catcgaccgg gaagagaagc gcagccagta
     4921 cctgcgggac ggacaggccg catggcagca ctatcaggaa acgggtctgc accttactgc
     4981 ggaagaagcg gaagcctgga taagtacctg gggaactgag aacgagcagg atgctccgcc
     5041 atgccacagg taacgatttc cgcgctggca cagcgcgatt tacaacgcct tcaggacttt
     5101 ctcaaaacca aaaatcggct ggcagccaga aaaggaggtg aggtgatcgt ccgggctatc
     5161 cagcaactga aaacattgcc agacattggc cgcccggtgc cgtttctgcc gctggaatat
     5221 aaggaactgg tgatcgggtt tggcgacagt ggctatgtga tgctctaccg ccacgaccgg
     5281 gaaatggacc agattgtgat cgtcaccgtc aggcatcaga aagaatccgg gtatccgggg
     5341 gcagacagcc tctaataacc gatgacgggg gcgcaattca ttgcgtggcc gtcgccggtt
     5401 tgacaagcgc agcgcgtcag aaaaccacat cctgaacgga aaaacgggta aaattcagcg
     5461 atacatttac cgtgagaaat tacacacctt tcacacccga taaaatcagg ggtatacagt
     5521 ggcgaaaaca ttgctcaacc tttcacaggc agcacaagcc gcgggcatta ccagaagaac
     5581 gctatacaat catgtaaaac agggaaaggt taccgtgtca cgtgacggga aaaacaaccc
     5641 tgtcgtggat gtgtcagaac tgatccgtgt atacggaaat gtgaatatcc ctgagaaaca
     5701 aattcccggc atttcacacc gtgaaaatac acaaaaaaat ttcccacagg aacagcttct
     5761 ggcaatgcaa aaggaactgg ccgatctccg gcaggctgtc accctgatgc tggaagataa
     5821 aacatcccgg gaagaagaac gccgccagca cgatgatgag cgccggaaac tccaggccga
     5881 agtggacaga ttgacaacag aactgacaca gaagaaaaaa cgcttctggt ccggctggtt
     5941 tagctgagaa cttaccgaag ggaatggaga acatgacgaa gcaggaaaaa actgccctca
     6001 atatggctaa attcattaag gatcagtcgc tgctgttgct ggaaaagctg aacgagctgg
     6061 acatggatac cccggccgac atgtgcgaac ggcttcacga ggatgcggaa acactctggc
     6121 aggtgatgcg ggataagctc ggggaagaat aacagcaccg gccatgccgg tgctggcgtt
     6181 attttttgcc gaacggccac caccggcggg cgggtttgtc ctccggcagt tcaggcaccg
     6241 gcacgttaaa atagcggctg ttatattccc gcatcagctc cgctttcagc ttctcgttca
     6301 ccgcgctttc cccgtgccgc tcgctgacca cctcaatcat cgcgttaatc tgctccggtg
     6361 agcacttccc ggcatcaacc acctgcacac cgttctcgat ggcgaaccgc tccacctttc
     6421 gatagaggta atcacacagc ttcattcctg tgggtttgtc ccgttcccat tgcggatttt
     6481 caccggtgaa aaagtacgtg gctttttcgt cgctgttgag ccgctcgtca tacatcccga
     6541 tggatttcat catcgccaga tgctgggccc ggtcgacaaa acagaaaaca tacgccccgg
     6601 tctgccaggc gagcaccacc atgtcttcca gatgctcgct ggttggcata atgcagcgct
     6661 cgccgtcttt gtcttccacg tcctcaataa ataccatgta cagcgccata atccctcact
     6721 ccgttgtcat aaatttaaag cacgcgaaca gcctctcccg gtccagctcc accgttttgc
     6781 gggcctcgcc ggtctgtgga ttcacgattt catccaccgc cagaatcgcc cgctgtaccc
     6841 ggacaagcgt cggccggtca gggcagatgt accagatttc atcgatgccg ttcgcccggc
     6901 ggttgaacag atacccggac accacttcct gataccgcct gcggctcttg acggtgcgct
     6961 ctacctcaaa tgccaccgtt ctgccgtcca gctccgccag cgcgtccggc actttcatcc
     7021 ctttcagggc catacggtgc aggtaccgcc agccggtggc cccccggccc tccatggaga
     7081 ggcgcaggga ctgcacggcc agccggtgcg gcagctgcgc cgccgacacc cttgacggct
     7141 gaaacggaat aacgtccgtc agcggctcgt cctcgtcgaa cgagaacgcc accccgtgcg
     7201 gcgtcagccc ccacacgctg acctgacggc cgtcaaccgg gtatttcgcc cggaccagca
     7261 gccctttcgc caccagactg tccaggaagc ggtaaaccgg ctgtaccgcc gcaatcccca
     7321 gccgtcgcgc aaccagctcc gccgtggaac acagctcttc ccgcagccag cgcagggtca
     7381 gccgtgtttt ctccgcgttc cgcgcctgcc gcttcgcgtg gctgacgttg tactgctcca
     7441 gtgtcatcag taaagccccg caaaatcatc atccgctttt ggtccgccgc cgtcggccgg
     7501 aggcaggtac tccgccagcg ggtccgtttt cgccagcacc gggaaggttt tcagcgaaat
     7561 ttcccggcgc tcaacccgca gcgggctgct gaacgccagc cgcgccacgc ccagcccggt
     7621 catcaccgcg aacccgtcag gcaggtgttg cagggtgttc acgtcaaaca gcggccgcgc
     7681 ctccttctgg atgaagctgt cgccgctgat gtgctccacg ttccccgcct cccggctggc
     7741 ccggcggcgc tccacgtcca cccggatctc cccggtctgg cccgccgccc actgcgcgga
     7801 ctcctggctg gccgcgcgat agaaccagcg gatcggcgtg ttatccagta ccgtggtttt
     7861 cacaaaatca gcgggcagat cctgcccgca ctgaccgaag tcgcccagcg actggtgcgc
     7921 gagcagcagg ttgcagtccc ggctgcgcag cgtccccagc gcgttcagca cgtacttcga
     7981 cagcagatat ttaatctcat cgagcatgat gctcgcgtgc ggccacctcc ggaactcatc
     8041 ccgcgcaatg atgatttgcg cgcagcgggc aaacagcatc ttctgcaccc ggatcaccgc
     8101 ctcatcgtcc atcgagccga tgacgtacag gcagccgccg ccgttgatta tccccgccac
     8161 atcgataccg ctgtccgtct gcaggacgct caggtcggcc acgttctcca gcttggtgat
     8221 cagccccttc acgtcctttt tcagggcctc cggcaacgcg tacgccgccg ccagcacctg
     8281 ctgaatgttt gccccctgcg ggaactgctc cgcaatcagc ttcgccgctt tctgctcgct
     8341 gatgcggtag tggtccgcca cgtcgccggt ctcactcagg ttaaacccgg caaccagcag
     8401 attcttcagg gcgtactggt cgagatcgcg gaacagattc agctgcgccg gtttccccgg
     8461 ccgcagatcc agcagggtga agtccgggca gtgcgcccgg aagacgtgcg gcgcccacgc
     8521 gtcccctttg gggtcgaagt acaccacagc gtccccgaaa tcgcgtacgc agcgaatgag
     8581 cgcgttggtg gccatcgcgc tcttgccgct cccgggcagg ccgaggatct gaatattggt
     8641 cttgcgccag gtatcacgag ggaccagcac cggctggccc tgctcatcct tacccagaaa
     8701 caccgcctgc tgtttccggg cctgctccgt ggaaaaatcg gccagcgcgt taaccggtac
     8761 cggctccccg aaatgcaggt ggcggacgtc tgtcatttct ccggtccgct ggctgctgcg
     8821 ccggctctcc tgattcagtt tcgcgttcac cgcctcgtca gcggccgcaa aatgaccatc
     8881 aagcagcagg aacgccagca gccgcgccag aaggacgccg gcgacaagcc ctccggcaca
     8941 ccaggctatc ccgaacaggt tagccggctg cagcaggtaa taatctgcgt tcgcatagag
     9001 gtccgggcgc aggacggttt ctccccagct ctcgataaac acggcgacaa ccagcccccc
     9061 cagaagggcc agaccggcag cgccggtcag ccagtacgcg tagttccaga catgtcgccg
     9121 tgccctgacc atccgcccgg gtgaatccag cgaggccagc accgaaaatg gcacagtccg
     9181 gttattatcg cgcttatagc gatcggcata ctcccgccgc gccttatggc tcagccccac
     9241 aaaacgcatt cggccggccc agagttcagc cagaccgaaa aacaggccga taaccagaaa
     9301 aaaaccggcc agactgtaat actcccggta cagccagctg acccacgggt aaatctgccg
     9361 ggccagctcc gggatatgcc actgccaggc aagcgaatcc gtattaaaca tgcaatctct
     9421 ctccttcaga cgacgggttt accggcgtga tgcgcagccc ccgctgcaca agccgcggac
     9481 atgccccaag gcatggcggc ggcggtcacg tccgtggtga ttgcgttcag ctttcaccgc
     9541 ggaggccagc ctctttccgc cccatgcgga aaaggcgcag ccccggagga acaacgagca
     9601 cgccccagcg tgtgagagga aaaggcggca ccccagtgcg gtcttttccg gtgttccggc
     9661 ccccgtcaga gttcgccata gcgagcggct gaccacccgc aaaatcagga gcagctttgc
     9721 tgcttcgtca ggtgcgtcca gcaccgtgga tttttgtggg tggtcaggcg tgagcctgac
     9781 gggggccggg tgaatttctg gcgtggccgg cgtccagccg gacagagcca gaaagagggg
     9841 aaaagaccgt gcgtcggtgg cgtccagcca gcgtaagcaa ggtcttttcc cctgaagtca
     9901 gccacgcccc agcggggatg acttgcattt ctccgcaagg agaaaaaagc aacagagata
     9961 ggttaacgta aaatgttcag cgaaaaaccg acatggttca cctatcctga taattgatcg
    10021 tcagggaata gaaagactta atcaggggac aatatcccac atcagcgcgt ccggtgaccg
    10081 tcttgcaggt gccggggaaa ttgcgcctcc tcgctcactc ggtcgctacg ctccgggcgt
    10141 gagactgcgg cgggcgctgc ggacacatac aaagttaccc acagattccg tggataagca
    10201 ggggactaac atgtgaggca aaacggcagg gccgcgccgg tggcgttttt ccataggctc
    10261 cgccctcctg ccagagttca cataaacaga cgctttttcg gtgcatctgt gggagccgtg
    10321 aggctcaacc atgaatctga cagtacgggc gaaacccgac aggacttaaa gatccccacc
    10381 gtttccggta ggtcgctccc tcttgcgctc tcctgttccg accctgccgt ttaccggata
    10441 cctgtccgcc gttctccctt gcgggaagtg tggcgctttc tcatagctca cacactggta
    10501 tctcggctcg gtgtaggtcg ttcgctccaa gctgggctgt aagcaagaac tccccgttca
    10561 gcccgactgc tgcgccttat ccggtaactg ttcacttgag tccaacccgg gaaagcacgc
    10621 aaaacgccac tggcagcagc cattggtaac tgggagttcg cagaggattt gtttagctaa
    10681 acacgcggtt gctcttgaag tgtgcgccaa agtccggcta cactggaagg acagatttgg
    10741 ttgctgtgct ctgcgaaagc cagttaccac ggttaagcag ttccccaact gacttaacct
    10801 tcgatcaaac cacctcccca ggtggttttt tcgtttacag ggcaaaagat tacgcgcaga
    10861 aaaaaaggat ctcaagaaga tcctttgatc ttttctactg aaccgcgatc cccgtcagtt
    10921 cagaggagga cgatggtgcc accgttccgc cctgaacatc ccggatataa tttgcctgac
    10981 atgcggccag aagaaagcca gcaacaatca atataaaaag aaaaatagtc tttacctttt
    11041 tcatatactt tccctgtatt taaagactcc ggcattcatc cctgaacacc ggaagtcagt
    11101 atttcaaatc atccttgata attttttgtt accagttacc gtcccgataa tcaaaagcta
    11161 tataacaatt atccacatca ggttttattt gatttttaaa aaatggctgt agtaaaggaa
    11221 cccattcttt cttcaaatca aactcaccat tattaatatt atcctttaaa ggcattccca
    11281 agctttcaat gacagaacca tcgtcaccaa agtctttaga atactcttcc cctttaaact
    11341 cttcagtttt cttatcaaac catgtcaaac gtaatttaag ccccatattt acctctcaaa
    11401 gatatttttt aatgttccgt tttggatctg gccctttaac ctgcttaccc gttttgggat
    11461 caaatgcgcc taggtgttcg ccatcactgg cacgataccc ttcaagctca ccgtgctggg
    11521 aatcccattc ataaatttta cgttttttat cgccatacca tcgggcccgc ttaccaccac
    11581 caccttgttt aggtgtttta ggatcacctc gctttaactc tccaagtccc tttatgtctt
    11641 ctgttttagg tactggatga taatcatggc cgtagtcttt agtccccttg cgaggcttgt
    11701 tcttttcctc atttaactta ttttctgcat ccttcgcttt tttctccttt tgtttccggc
    11761 tctccatcgc cccggtaagt gcagccttat ctctggataa ggattcattc attgcgttta
    11821 aagatgcctg agccgctttt aatttctcat tctgattctg aatatcctta tcaagatagc
    11881 gaacctgatc ctgccacccg gagccatatt catgaggcgg gttataagtc acaaaatcat
    11941 ctttatttgc ctctgcctct tttacctttt tatcggcttc ctgaacagca gcccttgcac
    12001 cggggagcgc cttctctgtc gatgcaatgc ggctgtttaa ggtcgcaata tttttatctt
    12061 cggcatccag ctcagctttc gctttatcat agtctctttt cagcccctct tccggatgag
    12121 cggcgtccca tgcctgctgg cgacgctttt cttcctcctg acgctgtttt acctgtgccg
    12181 gggtaagaac atctgtcacc gacacataaa ccggcttctg tccggtctct ttcgggaaac
    12241 gaataacggc ctcacgggag ttaccaccgg ctgtaaaacc agccggacgt gaatcacctt
    12301 tttcagcaac aatgcctttt ggcggggctt tcgctgtcgg aacacctttc ggtacgctca
    12361 cctgcagaga cgggagaccc ggaatcgaca cactgaatac ccccggacgt tttgtcggtt
    12421 tcgcatccac cacagggaca ctcattggcc gacctgcgac aaccgcaata tgctgccgct
    12481 catccttcac cacatccaca acccgttgtc tgacacgaac cgtcgcctgg tccagtggta
    12541 aagtacttgc cggagtctcc gtcaccgcat cggccggtaa tgacgtcata atttttgaca
    12601 tcattttcgg atcatctttt gcaatctcag aaggcagcac accgtagatc gcaatccccc
    12661 acagaccaaa cttaaacggc cccttcaggg cagccagcac atcagcaacg gcggccgaca
    12721 acgcatcgcc ggaaactgat aaagccagtc cttcagcccc cggagtagcc agggcaggca
    12781 gaccgaaggc catcgcagtg gccgaagact gtccgccacc agagctaccg ctatgattgc
    12841 cgctgttacc accattacca ccgggtttac tcccgccgtt accaaactcc cccggattat
    12901 agttatgaat atctccattc ggcgtatgcg tcgtacccca gcccggcccg ctgtttggat
    12961 ccgtaccacc acctgatgaa gggccacctt taccagacgt accgttcaca ttcccactgg
    13021 cctgaccacc attatgtccc agacctgaat tacccggacc tcgaccgtct ccaccactca
    13081 taccgttttc ctctttgaca tttaaaacaa taaattaaag ccaacatact gtacatatac
    13141 acagtataat tattacctta ctcctcccgt tttcaggtgt caatatatga gattagttct
    13201 catcttcagg cacaaaaaag cgcccggagc cacctgtaag cagatcgcgt cttttcccga
    13261 aaatttctca tggcaacaaa ttttattatt taagacattc atcacactta catttcagat
    13321 ggtatagaca catctgaaag ctaactggca tgaggagagg acctgcggtt aaactgttcg
    13381 ggaaacctga gacgcccgga ggccactatg acgcacctga aactgactcc cgctgaagaa
    13441 aagcgcctgg cggacgcctt tgtcgctcag gcactggcca tgggcctgaa agggaacaaa
    13501 acgctgccaa aggcggtaaa acaacaggtg cgggaaaggg tgcttcgtgc cattcaggac
    13561 gaacgtgaag ccaggcgggc gcaggaaatg cgtcgggaga aatacgaggc tacggaaacc
    13621 accttcacct ggcagccaca gcgccgccgg taaggggtat ttaccataac gtcgcattgc
    13681 ccgcaccgct cagacggtct gagggcgttt ccggcggcta cgggataaaa caggcaacaa
    13741 accacccgga aaaccgccgg aaacgcgccc ggtaaattgt aacccgctgc atgcctatgc
    13801 acgcaactgc atggcgggcc gtttggtgta aaaacgatac gataagccgt gtttatgtaa
    13861 atgaacgtgg ccgtaaagag tgacaaatat acatgtaaca ttttttactg acaggtcatc
    13921 aacccgatgc gtttaatacc ctttatcctg ctggcattgt gcagcccctt actcctgacg
    13981 gcctgtaagc attccaccac ccagccgccg aaaatttata ctctggataa gtcatctaaa
    14041 atcagtagct acgctgcggc catcaagacc gctgttgaaa tgcagatgtt tgaaccagag
    14101 gcctatgcgg gaaaaatgtg caccgtgcgg atatccatac aacgtgatgg cactctgaac
    14161 agcgccattg ctgaaggagg agatccgaaa ctctgtaaag cagcaatatc agccgttacc
    14221 cacgccaaaa ttccgccggc accggatgaa aatacctggc aaatattcaa aaacgcccct
    14281 ctggatttca gaccatgaaa gcttttactc tgacagtgct ggcggccatg ttcctcactc
    14341 cggtacatgc gataccacta aaacccgtaa ccacactgca gccaacctac ccggtacagg
    14401 ccgcagcaaa acgcatcgaa ggtcaggtga ccgccacgtt tgatattctg gacgatggac
    14461 gagtggacaa cgtgtcgctt accggctgtc accttttttt tcgggaaacg ctgacggcaa
    14521 tgaggcactg gctatatccc gcagggcacc cggcaatgcg acaggttata aattttgaat
    14581 tcagtctgaa aaatgacggc ttacaggatc cgcgaccagt caccacccaa aagctcaatg
    14641 atgatggttg ccgccagtaa caggtccttt aacccgcagg ctgcaatagt cctggatgat
    14701 gagtgagcct gtagcagccc tgattagtgg aagcgaagct gaaaaatggg cagcaaaagc
    14761 cgtatttctg gcaaatagcg ccgccacgga ttaaagtagt catgtgtaat acatatgact
    14821 acaaaggggc ttttatgtca tcagcaacat ccatcaggct cgatgaagaa cttaaggacc
    14881 ggctgaaaac gctggccgat gaccggcacc gctcagcgca cgcgctaatg ctggaggcaa
    14941 tcaccgaata catcgaccgg gaagagaagc gcagccagta cctgcgggac ggacaggccg
    15001 catggcagca ctatcaggaa acgggtctgc accttactgc ggaagaagcg gaagcctgga
    15061 taagtacctg gggaactgag aacgagcagg atgctccgcc atgccacagg taacgatttc
    15121 cgcgctggca cagcgcgatt tacaacgcct tcaggacttt ctcaaaacca aaaatcggct
    15181 ggcagccaga aaaggaggtg aggtgatcgt ccgggctatc cagcaactga aaacattgcc
    15241 agacattggc cgcccggtgc cgtttctgcc gctggaatat aaggaactgg tgatcgggtt
    15301 tggcgacagt ggctatgtga tgctctaccg ccacgaccgg gaaatggacc agattgtgat
    15361 cgtcaccgtc aggcatcaga aagaatccgg gtatccgggg gcagacagcc tctaataacc
    15421 gatgacgggg gcgcaattca ttgcgtggcc gtcgccggtt tgacaagcgc agcgcgtcag
    15481 aaaaccacat cctgaacgga aaaacgggta aaattcagcg atacatttac cgtgagaaat
    15541 tacacacctt tcacacccga taaaatcagg ggtatacagt ggcgaaaaca ttgctcaacc
    15601 tttcacaggc agcacaagcc gcgggcatta ccagaagaac gctatacaat catgtaaaac
    15661 agggaaaggt taccgtgtca cgtgacggga aaaacaaccc tgtcgtggat gtgtcagaac
    15721 tgatccgtgt atacggaaat gtgaatatcc ctgagaaaca aattcccggc atttcacacc
    15781 gtgaaaatac acaaaaaaat ttcccacagg aacagcttct ggcaatgcaa aaggaactgg
    15841 ccgatctccg gcaggctgtc accctgatgc tggaagataa aacatcccgg gaagaagaac
    15901 gccgccagca cgatgatgag cgccggaaac tccaggccga agtggacaga ttgacaacag
    15961 aactgacaca gaagaaaaaa cgcttctggt ccggctggtt tagctgagaa cttaccgaag
    16021 ggaatggaga acatgacgaa gcaggaaaaa actgccctca atatggctaa attcattaag
    16081 gatcagtcgc tgctgttgct ggaaaagctg aacgagctgg acatggatac cccggccgac
    16141 atgtgcgaac ggcttcacga ggatgcggaa acactctggc aggtgatgcg ggataagctc
    16201 ggggaagaat aacagcaccg gccatgccgg tgctggcgtt attttttgcc gaacggccac
    16261 caccggcggg cgggtttgtc ctccggcagt tcaggcaccg gcacgttaaa atagcggctg
    16321 ttatattccc gcatcagctc cgctttcagc ttctcgttca ccgcgctttc cccgtgccgc
    16381 tcgctgacca cctcaatcat cgcgttaatc tgctccggtg agcacttccc ggcatcaacc
    16441 acctgcacac cgttctcgat ggcgaaccgc tccacctttc gatagaggta atcacacagc
    16501 ttcattcctg tgggtttgtc ccgttcccat tgcggatttt caccggtgaa aaagtacgtg
    16561 gctttttcgt cgctgttgag ccgctcgtca tacatcccga tggatttcat catcgccaga
    16621 tgctgggccc ggtcgacaaa acagaaaaca tacgccccgg tctgccaggc gagcaccacc
    16681 atgtcttcca gatgctcgct ggttggcata atgcagcgct cgccgtcttt gtcttccacg
    16741 tcctcaataa ataccatgta cagcgccata atccctcact ccgttgtcat aaatttaaag
    16801 cacgcgaaca gcctctcccg gtccagctcc accgttttgc gggcctcgcc ggtctgtgga
    16861 ttcacgattt catccaccgc cagaatcgcc cgctgtaccc ggacaagcgt cggccggtca
    16921 gggcagatgt accagatttc atcgatgccg ttcgcccggc ggttgaacag atacccggac
    16981 accacttcct gataccgcct gcggctcttg acggtgcgct ctacctcaaa tgccaccgtt
    17041 ctgccgtcca gctccgccag cgcgtccggc actttcatcc ctttcagggc catacggtgc
    17101 aggtaccgcc agccggtggc cccccggccc tccatggaga ggcgcaggga ctgcacggcc
    17161 agccggtgcg gcagctgcgc cgccgacacc cttgacggct gaaacggaat aacgtccgtc
    17221 agcggctcgt cctcgtcgaa cgagaacgcc accccgtgcg gcgtcagccc ccacacgctg
    17281 acctgacggc cgtcaaccgg gtatttcgcc cggaccagca gccctttcgc caccagactg
    17341 tccaggaagc ggtaaaccgg ctgtaccgcc gcaatcccca gccgtcgcgc aaccagctcc
    17401 gccgtggaac acagctcttc ccgcagccag cgcagggtca gccgtgtttt ctccgcgttc
    17461 cgcgcctgcc gcttcgcgtg gctgacgttg tactgctcca gtgtcatcag taaagccccg
    17521 caaaatcatc atccgctttt ggtccgccgc cgtcggccgg aggcaggtac tccgccagcg
    17581 ggtccgtttt cgccagcacc gggaaggttt tcagcgaaat ttcccggcgc tcaacccgca
    17641 gcgggctgct gaacgccagc cgcgccacgc ccagcccggt catcaccgcg aacccgtcag
    17701 gcaggtgttg cagggtgttc acgtcaaaca gcggccgcgc ctccttctgg atgaagctgt
    17761 cgccgctgat gtgctccacg ttccccgcct cccggctggc ccggcggcgc tccacgtcca
    17821 cccggatctc cccggtctgg cccgccgccc actgcgcgga ctcctggctg gccgcgcgat
    17881 agaaccagcg gatcggcgtg ttatccagta ccgtggtttt cacaaaatca gcgggcagat
    17941 cctgcccgca ctgaccgaag tcgcccagcg actggtgcgc gagcagcagg ttgcagtccc
    18001 ggctgcgcag cgtccccagc gcgttcagca cgtacttcga cagcagatat ttaatctcat
    18061 cgagcatgat gctcgcgtgc ggccacctcc ggaactcatc ccgcgcaatg atgatttgcg
    18121 cgcagcgggc aaacagcatc ttctgcaccc ggatcaccgc ctcatcgtcc atcgagccga
    18181 tgacgtacag gcagccgccg ccgttgatta tccccgccac atcgataccg ctgtccgtct
    18241 gcaggacgct caggtcggcc acgttctcca gcttggtgat cagccccttc acgtcctttt
    18301 tcagggcctc cggcaacgcg tacgccgccg ccagcacctg ctgaatgttt gccccctgcg
    18361 ggaactgctc cgcaatcagc ttcgccgctt tctgctcgct gatgcggtag tggtccgcca
    18421 cgtcgccggt ctcactcagg ttaaacccgg caaccagcag attcttcagg gcgtactggt
    18481 cgagatcgcg gaacagattc agctgcgccg gtttccccgg ccgcagatcc agcagggtga
    18541 agtccgggca gtgcgcccgg aagacgtgcg gcgcccacgc gtcccctttg gggtcgaagt
    18601 acaccacagc gtccccgaaa tcgcgtacgc agcgaatgag cgcgttggtg gccatcgcgc
    18661 tcttgccgct cccgggcagg ccgaggatct gaatattggt cttgcgccag gtatcacgag
    18721 ggaccagcac cggctggccc tgctcatcct tacccagaaa caccgcctgc tgtttccggg
    18781 cctgctccgt ggaaaaatcg gccagcgcgt taaccggtac cggctccccg aaatgcaggt
    18841 ggcggacgtc tgtcatttct ccggtccgct ggctgctgcg ccggctctcc tgattcagtt
    18901 tcgcgttcac cgcctcgtca gcggccgcaa aatgaccatc aagcagcagg aacgccagca
    18961 gccgcgccag aaggacgccg gcgacaagcc ctccggcaca ccaggctatc ccgaacaggt
    19021 tagccggctg cagcaggtaa taatctgcgt tcgcatagag gtccgggcgc aggacggttt
    19081 ctccccagct ctcgataaac acggcgacaa ccagcccccc cagaagggcc agaccggcag
    19141 cgccggtcag ccagtacgcg tagttccaga catgtcgccg tgccctgacc atccgcccgg
    19201 gtgaatccag cgaggccagc accgacatgc aatctctctc cttcagacga cgggtttacc
    19261 ggcgtgatgc gcagcccccg ctgcacaagc cgcggacatg ccccaaggca tggcggcggc
    19321 ggtcacgtcc gtggtgattg cgttcagctt t
//
