LOCUS       NZ_MW191862            34643 bp    DNA     circular CON 28-MAY-2024
DEFINITION  Escherichia coli plasmid pHM1-5, complete sequence.
ACCESSION   NZ_MW191862
VERSION     NZ_MW191862.1
DBLINK      BioProject: PRJNA224116
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34643)
  AUTHORS   Zhu,L. and Hong,C.
  TITLE     Deciphering of last resort antibiotic resistance genes in hospital
            wastewater treatment systems resistomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 34643)
  AUTHORS   Zhu,L. and Hong,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2020) College of Environmental and Resource
            Sciences, Zhejiang University, 866 Yuhang Tang Road, Hangzhou,
            Zhejiang 310058, China
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022700315.1-RS_2024_05_28
            Annotation Date                   :: 05/28/2024 03:43:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 42
            CDSs (total)                      :: 42
            Genes (coding)                    :: 41
            CDSs (with protein)               :: 41
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 1
            CDSs (without protein)            :: 1
            Pseudo Genes (ambiguous residues) :: 0 of 1
            Pseudo Genes (frameshifted)       :: 0 of 1
            Pseudo Genes (incomplete)         :: 1 of 1
            Pseudo Genes (internal stop)      :: 1 of 1
            Pseudo Genes (multiple problems)  :: 1 of 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MW191862.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..34643
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:562"
                     /plasmid="pHM1-5"
     gene            1..717
                     /locus_tag="MTW41_RS00005"
     CDS             1..717
                     /locus_tag="MTW41_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            729..1823
                     /locus_tag="MTW41_RS00010"
     CDS             729..1823
                     /locus_tag="MTW41_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            1850..1999
                     /locus_tag="MTW41_RS00015"
     CDS             1850..1999
                     /locus_tag="MTW41_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227648764.1"
                     /translation="MSLNWILVFVDKHITSGWSRKRKLITQLVILITGITLFKVLGGIS
                     QSWL"
                     /name="hypothetical protein"
     gene            2338..3024
                     /locus_tag="MTW41_RS00020"
     CDS             2338..3024
                     /locus_tag="MTW41_RS00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            3021..3929
                     /gene="virB9"
                     /locus_tag="MTW41_RS00025"
     CDS             3021..3929
                     /gene="virB9"
                     /locus_tag="MTW41_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            3922..5040
                     /gene="virB10"
                     /locus_tag="MTW41_RS00030"
     CDS             3922..5040
                     /gene="virB10"
                     /locus_tag="MTW41_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            5042..5383
                     /locus_tag="MTW41_RS00035"
     CDS             5042..5383
                     /locus_tag="MTW41_RS00035"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_242647343.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVDWPPES
                     PDNQYHLNK"
                     /name="hypothetical protein"
     gene            5425..6653
                     /locus_tag="MTW41_RS00040"
     CDS             join(5425..5740,5740..6653)
                     /locus_tag="MTW41_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558215.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS2 family transposase"
                     /protein_id="WP_088895425.1"
                     /translation="MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQ
                     LFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVEYG
                     RGKKVDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWMDGRRSRHTDDTDVLLR
                     IHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRVYRIMRQNALLLERKPAVPPSKR
                     AHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHWAVTTGGFNSETVQ
                     DVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGI
                     AESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRACN
                     GLSDNRCLEI"
                     /name="IS3-like element IS2 family transposase"
     gene            6711..7406
                     /gene="virB11"
                     /locus_tag="MTW41_RS00045"
     CDS             6711..7406
                     /gene="virB11"
                     /locus_tag="MTW41_RS00045"
                     /inference="COORDINATES: protein motif:HMM:TIGR02788.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_053002790.1"
                     /translation="MRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNI
                     AAFMELAVAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYV
                     HLFYPSESGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMT
                     SIHAASAKDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIY
                     YKGAECENF"
                     /name="virB11"
     gene            7393..9255
                     /gene="taxB"
                     /locus_tag="MTW41_RS00050"
     CDS             7393..9255
                     /gene="taxB"
                     /locus_tag="MTW41_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            9264..9686
                     /locus_tag="MTW41_RS00055"
     CDS             9264..9686
                     /locus_tag="MTW41_RS00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            9670..9975
                     /locus_tag="MTW41_RS00060"
     CDS             9670..9975
                     /locus_tag="MTW41_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_001350475.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            <10088..10282
                     /locus_tag="MTW41_RS00065"
                     /pseudo=""
     CDS             <10088..10282
                     /locus_tag="MTW41_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            10286..10858
                     /locus_tag="MTW41_RS00070"
     CDS             10286..10858
                     /locus_tag="MTW41_RS00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001198960.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            10863..13016
                     /locus_tag="MTW41_RS00075"
     CDS             10863..13016
                     /locus_tag="MTW41_RS00075"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            13013..13219
                     /gene="hha"
                     /locus_tag="MTW41_RS00080"
     CDS             13013..13219
                     /gene="hha"
                     /locus_tag="MTW41_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            13237..13701
                     /locus_tag="MTW41_RS00085"
     CDS             13237..13701
                     /locus_tag="MTW41_RS00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            13788..14492
                     /locus_tag="MTW41_RS00090"
     CDS             13788..14492
                     /locus_tag="MTW41_RS00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            15275..15370
                     /gene="dqlB"
                     /locus_tag="MTW41_RS00210"
     CDS             15275..15370
                     /gene="dqlB"
                     /locus_tag="MTW41_RS00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            16033..16680
                     /locus_tag="MTW41_RS00095"
     CDS             16033..16680
                     /locus_tag="MTW41_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            16755..17024
                     /locus_tag="MTW41_RS00100"
     CDS             16755..17024
                     /locus_tag="MTW41_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            17185..17814
                     /locus_tag="MTW41_RS00105"
     CDS             17185..17814
                     /locus_tag="MTW41_RS00105"
                     /inference="COORDINATES: protein motif:HMM:NF022440.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_223424520.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLRYKL"
                     /name="DUF2806 domain-containing protein"
     gene            17988..19610
                     /locus_tag="MTW41_RS00110"
     CDS             17988..19610
                     /locus_tag="MTW41_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MCR-1 family phosphoethanolamine--lipid A
                     transferase"
                     /protein_id="WP_242647341.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDALLATDDFIAQSIQWLQTHSNAYDVS
                     MLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAI
                     TPTLLKLFDVTADKVKDRTAFIR"
                     /name="MCR-1 family phosphoethanolamine--lipid A
                     transferase"
     gene            19658..20386
                     /locus_tag="MTW41_RS00115"
     CDS             19658..20386
                     /locus_tag="MTW41_RS00115"
                     /inference="COORDINATES: protein motif:HMM:NF013718.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_242647342.1"
                     /translation="MGGGVGFVMPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVA
                     DWFYLGMGHWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKW
                     LVPVTKFRVRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRN
                     TIPDKCFPAAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKDDYWRSFFEP
                     YGGVDDACVGDVGRACVGVF"
                     /name="phosphatase PAP2 family protein"
     gene            complement(20796..21323)
                     /locus_tag="MTW41_RS00120"
     CDS             complement(20796..21323)
                     /locus_tag="MTW41_RS00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(21458..21862)
                     /locus_tag="MTW41_RS00125"
     CDS             complement(21458..21862)
                     /locus_tag="MTW41_RS00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(21875..22741)
                     /locus_tag="MTW41_RS00130"
     CDS             complement(21875..22741)
                     /locus_tag="MTW41_RS00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473366.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001353743.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGVKDYKYPDYPAF
                     KRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFD
                     KMYPPEN"
                     /name="replication initiation protein"
     gene            24156..24671
                     /locus_tag="MTW41_RS00135"
     CDS             24156..24671
                     /locus_tag="MTW41_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            24776..25318
                     /locus_tag="MTW41_RS00140"
     CDS             24776..25318
                     /locus_tag="MTW41_RS00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            25315..25566
                     /locus_tag="MTW41_RS00145"
     CDS             25315..25566
                     /locus_tag="MTW41_RS00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            25553..25780
                     /locus_tag="MTW41_RS00150"
     CDS             25553..25780
                     /locus_tag="MTW41_RS00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            26315..26533
                     /locus_tag="MTW41_RS00155"
     CDS             26315..26533
                     /locus_tag="MTW41_RS00155"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005058042.1"
                     /translation="MHKDTGQQYVVIFTDNNKIRDYKAGIVPQFGELKQSDVDLVLFYR
                     DEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            26624..26974
                     /locus_tag="MTW41_RS00160"
     CDS             26624..26974
                     /locus_tag="MTW41_RS00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            27279..27527
                     /locus_tag="MTW41_RS00165"
     CDS             27279..27527
                     /locus_tag="MTW41_RS00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            27524..27871
                     /locus_tag="MTW41_RS00170"
     CDS             27524..27871
                     /locus_tag="MTW41_RS00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            28232..28735
                     /gene="taxA"
                     /locus_tag="MTW41_RS00175"
     CDS             28232..28735
                     /gene="taxA"
                     /locus_tag="MTW41_RS00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            28739..29968
                     /gene="taxC"
                     /locus_tag="MTW41_RS00180"
     CDS             28739..29968
                     /gene="taxC"
                     /locus_tag="MTW41_RS00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            30045..30338
                     /locus_tag="MTW41_RS00185"
     CDS             30045..30338
                     /locus_tag="MTW41_RS00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_060598542.1"
                     /translation="MTEHDAICISGLHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            30335..30550
                     /locus_tag="MTW41_RS00190"
     CDS             30335..30550
                     /locus_tag="MTW41_RS00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            30906..31526
                     /locus_tag="MTW41_RS00195"
     CDS             30906..31526
                     /locus_tag="MTW41_RS00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            31540..31866
                     /locus_tag="MTW41_RS00200"
     CDS             31540..31866
                     /locus_tag="MTW41_RS00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            31885..34632
                     /locus_tag="MTW41_RS00205"
     CDS             31885..34632
                     /locus_tag="MTW41_RS00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     ARG             17989..19607
                     /name="mcr-1"
                     /gene="mcr-1"
                     /gene_name="MCR-1 family phosphoethanolamine--lipid A
                     transferase"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="99.82"
                     /coverage="100.0"
     ARG             17989..19610
                     /name="MCR-1.1"
                     /gene="MCR-1.1"
                     /gene_name="MCR phosphoethanolamine transferase"
                     /tool="rgi"
                     /drug_class="peptide antibiotic"
                     /identity="99.82"
                     /coverage="99.82"
     Typing          complement(21876..22747)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          28740..29965
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          730..1796
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.6999999999999997e-172"
     Typing          2339..3021
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          3022..3926
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7394..9252
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaaacgtg taaaaacatt gatgctgata tcattattga cggcttcatt ttatagtagc
       61 gcaggaattc cggttgctat tgatgccagt ccggaatggg ctgttgaagc cgcaagatgg
      121 acagaacgac tcaaacaatg gtccgaaact gcgcaacatt atcagagtca gattcaggca
      181 tataaagacc agttagccac ggcaacaggt ataaggaata ttgcggcatt cacaaatgaa
      241 ctaagtaatc tacaatcaga actgacaaat atttataagc aggggaacag ttatatttct
      301 gattttacca gtaatcccga aggtgcattg agcagccagg ctaaaaatct gttcagcaag
      361 tatggagcct tcgatatgtg taatacgggc tatgaacgta atgataatct ctgtaaagca
      421 cggattgtgt caacggctgc cagtattgaa cagggaaatg agatcaataa gcagttatca
      481 agtgcaatgt ctcagattca gagtttaagt agccgaattg aggcttcaaa ggatatcaaa
      541 gaatcccagg atttggctaa cgcattacag gcgcagtcgt taaaaatgca ggcgataaaa
      601 atgcagtatg atgtctggaa taataaaaat aaagcagatc atgagatgtt ggtcacacaa
      661 gaacaagagg cctttattaa acagcagaaa gaagctgaac cattaacttt tgattaaaag
      721 gtggatatat ggctcagggg tttttcgtta aatataattc taccgttatg gattcggtag
      781 ataaaatcag ctccagttat caaacacaat ttgctaatga tattatgtcg ttagcaacgg
      841 tatcggttac gttatatgta ctatggaaag gatatcaaat acttgccagt aaaactcaga
      901 cgcccttgca ggatttagta tgggatctat caaaatttgc aatcataatc atgtttataa
      961 ctaatgcgga tgggtattta actgcggcta ctgatgcgtt gcaaggcatg aaagatggtt
     1021 tttctggagg ggtgagtgtc tggcaaactt tagataactt atggaaaagt acgcaaaatc
     1081 ttggtgcgga aatatactct ttagataaat caacatatgt taaagatcaa ggtgtagttg
     1141 gtcagttttt aatatggact ggctcgctta ttttaatggc tgttagtgtg gttgtttttt
     1201 taacagcaga tgtaacgatg aaactcctga ttattacagc accgatattt atcttttgtc
     1261 tcatgtttgg ttttattcgg agcatgttta ataattggtt acaatcgtta ttctccagta
     1321 ttctgacagt tctatttgcc agtttagtga ttcggatagc aatggatttt caagggatga
     1381 tcctttccca tgctattcgt gctgcacaaa cagggaatgt aaatcttgta tctacaggtg
     1441 ctatgggctt tatggctggg tttttggggg ctttattggt tcttatagct aaaggttttg
     1501 ctgtccagtt agcaggtgca ggtgttgaag gtgctgttca gggcgcagcc atgatggggc
     1561 tgggtgctgc tggtatggct actggtaagt ctctgatgct tggcggtcgt gctggtttag
     1621 gttttggctt agggatggcc ggaagaacgg gcatgaattc tttatcaggg aaagcaggga
     1681 atctgatggg gcgtggtgcg cgaacagccg ctgaatgggc gggtgaaaag ggatatcagg
     1741 cgctggctcc gacaggtgct ttggggatga aggcgagaag acttgcatcc ctggaaaaag
     1801 cacgagcgag gaacgccgca tgaaaataat gaaacgtttt ttttatgtga tgtccctgaa
     1861 ctggatactg gtgttcgttg ataaacatat cacctccgga tggagcagga agagaaagct
     1921 aataacccag cttgttattt taatcacggg aattacctta tttaaggtct taggtggaat
     1981 cagtcagagc tggttgtgac atgcttcatt attttgtcat gatactttat tttgtcctaa
     2041 tccttctttt aggagtgttt acctgcttcg caggaataag acttggttta gggcttgcgg
     2101 ggaaatggag aaagggtatg gatcttcgct ttttgcttct tattggtggg attctttttc
     2161 ttcatcttgg cctttatctc ttaaaggtgt tcgtgaacgc ttaataaggt gaatttatgc
     2221 gatgtgtgat tcttttgttt ttcctgtttc agatttccgg atgtaccaca aggaataacc
     2281 ttccttctga tgtttccggc gaactggaac ccattaacca cagccaggta atcagttatg
     2341 agtgaaaaaa tcgaaaagaa gattgagaca gctaaatcct tcgaaagaca actctatgca
     2401 gaaaatgaac ggtctaagaa aaatgcatgg cgtgttgcag tggcagcatc attactgtcc
     2461 ttatgtcttg gggctgcaat ttgtgttctt gtgccattaa aagaaaaaga gcttgctatt
     2521 gtggctgttg gcgaaaaaac aggccgtaca gaactgatta ctcaggttaa acaggaaaag
     2581 atcctgcaat ctgaagcact tgggcggtat tttgtaaaca cgtatattac tttacgtgaa
     2641 ggttataatt atccgtctct tcagtatgat tatgagactg tacagctata tagctcgaat
     2701 acagtaaagg acgattatct tcgtctgtat aacagcgata tggctcctga taaaatttat
     2761 cataataacg gttcttacgt tgcggttgag gtcatctcca atattatttc tgacgcaacc
     2821 gcgccagata aactggcctc tgtgcgcttt aaaaaaacga cgagaaactt cacgaccgga
     2881 caggtttcag tttcatactg gacggctcgt gtgacatatc gttttgaacc agaaaagtcg
     2941 gttaaaagtt ccagtcgtga gcttaatcct ctcggtttta ctgtaaccag ttaccagaca
     3001 gatcgggaag tcagggggga atgatgaaga aattatttat tgctacatgt ttattgcttc
     3061 ctgggcttgt gtattcagca gcgactccgt taccttctgg atttgatgca aggatgcaga
     3121 ctgtgagtta taacggtgcg aatacgaccg ttatccggtc aaagacagga tttctcacat
     3181 cagttgtttt tgatgaaggt gaggctgtta tcagtgcaaa ggctggtttt cctgccggat
     3241 gggaaatcac aaccgatgat aatgttgttt acatcaatcc gcgtcccgtt gttcaggaac
     3301 aggaaggcga tgaaggcgaa aaactgaaaa aggttttcca gccaacagaa aaggaatggg
     3361 atacgaatct ttttgtcaga acaacaaagc ggatttacag tctggatcta atccttctgt
     3421 cagaagaaaa acaagcgcaa cctgcttatg ttgtacaatt ccgctatcca tcagaaatag
     3481 cgaaaaagaa tgcagaagaa gtaaggctgg caaaagaaaa acaggaaaaa ctcagacaga
     3541 agaaactgat ttctgaaagt tttgaaaaag ccgatgcgcc taaaaactgg aattatttca
     3601 tgcgagtcaa tgaaaaatat gacagtcgtc gtatcgcccc tgattttgct tatgataatg
     3661 gcatatttac ctttttaggt tttaactcag ggaaagtatt cccagctcca tttgctgtaa
     3721 gagatggtca ggaacagaca cttgctttta atgtggaaac aaaaggcaag tataaaatta
     3781 tggttatcca caacgttaat gacaaatttg ttttacgcta tggaaacagc gttgttggtg
     3841 ttgtgaataa atctttcgga aaagtattaa ccgaccagag gaatacatct tctcctgcgg
     3901 tagaacgtgt tgaggtgaat aatgactgat atgaaaaaaa cagatgattt agttgatgat
     3961 gcgaatcagt caaagctgga aagtaaaccc gttcatgata tcggtgatat caggaacaaa
     4021 aataatcgta tgcgttctgg ctttctgttt ggtctgatgg ctgtattagt tattggtatt
     4081 tttgcgctga aaacatataa aaattatttt gcagatgacc agcagaaagc atcagaatca
     4141 acaggcgata ccagcatttc tcaggtaagt aaaatccgta ctggtcttgg tcagaatttt
     4201 gaccctgttg agaacaaagc aattatcaat ccaggcgcta ctggttctgg taatactgtt
     4261 tctgacggtc ataaagaagt gccacaggag gggttcagga aatatttgtc aatacctgtt
     4321 gctggtcagg gagggagtca gactggcgcg agtggcagca gcaggacatc gcagacatca
     4381 gagccacagg aagaaaggaa agaatcaaaa gaaaatgtgc ctggtaaatc aggaatgaaa
     4441 gtaactgcga ttaatctcga tcctgatctc tatattgagg aaaacaggct tataccgtgt
     4501 gctttaacca cacgctttgt ttctgatgtt gcaggtcgta tcagttgtgt ttttacagaa
     4561 gatgtatgga gtgctaatca ccacacaaaa ttactggaac agggaactaa ggcttttggt
     4621 cgttaccaga ccggaacgct gaatcatgga cagggcagaa tgttcgttat gtgggagcag
     4681 ttgcggacgc ctgataataa acgaatcgat atggtaaata cagcagcagc tggtcccctg
     4741 ggagaagcgg gcattgatgg atggatcgat tctcacttct gggagcgttt tggtggttct
     4801 cttatgctca gtatggttca ggatgtagcg gcggcggcgg cggataatgc acctggtaaa
     4861 gatcgtaatg tggattatac cgaaaactca cgacaggcaa tggctgaaat ggctaaagtc
     4921 gcacttgaga attcgataaa tattcctcca acaatgtata aaaaccaggg tgacataatc
     4981 actattatgg tcggggaaga cattgatttt tctgatatct atgagttaaa ggtaaaatag
     5041 tatgagtggc gttattcctg tcagcattag caataaatcg ctcgattttt ataaaaatca
     5101 agtattccag tcttttcttg atattgaagg gctaacagaa attgctgtca accgtcctgg
     5161 tgaaatctgg acggaaatta atggtgactg gacattccat aataatgaca gtgtgacctt
     5221 tgatttttgt aaacgttttt ctcatacgct ggcatcattt cggggagatg aaatcggcga
     5281 gaccaagcca ttactttcag caacactgga atcaggagaa cgtgtacagg tcgtagactg
     5341 gccccctgaa tctccagaca accagtatca cttaaataag tgatagtctt aatactagtt
     5401 tttagactag tcattggaga acagatgatt gatgtcttag ggccggagaa acgcagacgg
     5461 cgtaccacac aggaaaagat cgcaattgtt cagcagagct ttgaaccggg gatgacggtc
     5521 tccctcgttg cccggcaaca tggtgtagca gccagccagt tatttctctg gcgtaagcaa
     5581 taccaggaag gaagtcttac tgctgtcgcc gccggagaac aggttgttcc tgcctctgaa
     5641 cttgctgccg ccatgaagca gattaaagaa ctccagcgcc tgctcggcaa gaaaacgatg
     5701 gaaaatgaac tcctcaaaga agccgttgaa tatggacggg caaaaaagtg gatagcgcac
     5761 gcgcccttat tgcccgggga tggggagtaa gcttagtcag ccgttgtctc cgggtgtcgc
     5821 gtgcgcagtt gcacgtcatt ctcagacgaa ccgatgactg gatggatggc cgccgcagtc
     5881 gtcacactga tgatacggat gtgcttctcc gtatacacca tgttatcgga gagctgccca
     5941 cgtatggtta tcgtcgggta tgggcgctgc ttcgcagaca ggcagaactt gatggtatgc
     6001 ctgcgatcaa tgccaaacgt gtttaccgga tcatgcgcca gaatgcgctg ttgcttgagc
     6061 gaaaacctgc tgtaccgcca tcgaaacggg cacatacagg cagagtggcc gtgaaagaaa
     6121 gcaatcagcg atggtgctct gacgggttcg agttctgctg tgataacgga gagagactgc
     6181 gtgtcacgtt cgcgctggac tgctgtgatc gtgaggcact gcactgggcg gtcactaccg
     6241 gcggcttcaa cagtgaaaca gtacaggacg tcatgctggg agcggtggaa cgccgcttcg
     6301 gcaacgatct tccgtcgtct ccagtggagt ggctgacgga taatggttca tgctaccggg
     6361 ctaatgaaac acgccagttc gcccggatgt tgggacttga accgaagaac acggcggtgc
     6421 ggagtccgga gagtaacgga atagcagaga gcttcgtgaa aacgataaag cgtgactaca
     6481 tcagtatcat gcccaaacca gacgggttaa cggcagcaaa gaaccttgca gaggcgttcg
     6541 agcattataa cgaatggcat ccgcatagtg cgctgggtta tcgctcgcca cgggaatatc
     6601 tgcggcagcg ggcttgtaat gggttaagtg ataacagatg tctggaaata taggggcaaa
     6661 tccaggtcgt ttttcctcct gcatgtgaga gaaatactat ttcaatcact atacgtaaac
     6721 catcgacacg gcagataaca cataaagaat atgtggcgaa cggtttttat gattatgtcc
     6781 agtcaggaaa aaaacacagg acatacgatg atgagcttct tgatttattc agagcgagaa
     6841 atatcgctgc ttttatggag cttgccgtag cagcagggaa aaccattgta tttgccggag
     6901 caacgggttc cggtaaaaca acttatatga agagtcttat cgatttcata ccattgaata
     6961 cacggctgat tacgattgaa gatgcagagg aaatcaaatt ttttatccat aaaaattatg
     7021 tgcatctttt ttacccttcg gaatccggca gtgattccgg ctctatcata acagcagcga
     7081 aattaatcaa atcctgtttg aggatgaaac ctgacagaat tttactggcg gaaattaaag
     7141 gtggcgatgc ctgggatttt gtgaaagttg ctggttctgg tcacagtgga agcatgacgt
     7201 ccattcacgc ggcctcggca aaagatgcca tcattcagat ggtgacaaaa tgttatcaga
     7261 acagagaatg tcagaatctt ccttttgatg ttcttcgtaa aatcattatg gacagtattg
     7321 atattgttgt tcatgtaggc agggatggtg ttgtcaggca tatgagcgac atctattaca
     7381 aaggggctga atgtgaaaac ttttaataag tcgcaatctg tttttatatt cgctgttatg
     7441 cttgttgcgg catggtttgc aggttcattt attttctttg tgctttactt cagccagata
     7501 aagaatctga aaccattgaa ggctgtgttc agatccattg atgcgtacag gatggatatt
     7561 tttacagaca gccttacttt atctgttgtg actacggata tcagagtttt agcctttgtt
     7621 gcacttggag caggatttgt cgtgtctctt atcatccctg ttgcggcgtt gataaaactg
     7681 aacgagaaga aagaaaatat tttcggtgat gcgcgatttg caacaattaa tgatattcgt
     7741 gagtctaaca gtttcacgct tgacggtgac gaaaaagacg ggattatcgt tggtataaaa
     7801 gacaagaaaa tcatacgcta tgtgggagca gcattcagtg ctatgggagc cggaacaagg
     7861 gctggtaaag gtgctggtat agtcatcact aatcttatga agtactggtg gagtgttatt
     7921 attctcgatc caaaaaggga gtgttttaat atcaccagtc ttatcaggaa ggtgatttta
     7981 ggtcatgagg tttataaatt tgatcccttt agttcggtaa cgcaccgctt taaccctttg
     8041 tattatgtca gcatgggaac gagtgaaggt tttaatcagc ttgaaaatct ttcgttgatt
     8101 atttacccct ataagacaga tggtgcggat gctggtagct atcttaataa gacggcgggt
     8161 ggtgttttta aatcttatgc tgtcgcttta tggtttatga ttaagaatga taaggctgga
     8221 ctaaaaacgc ttgatattga gcctgtcttc tcaatgtcta aaattaatca gctttttgag
     8281 cgtgcagaac ccgaacatct tctttcattc atgaatgata ttcgttcaga attaaggggg
     8341 aaagacaaaa cgcttgctga tattggtgtc gctggcctta aggcattcat tgagatggag
     8401 gataaaacaa aagcacaact caaaagcaac tttcttaatg gattatcacc gtttgctaac
     8461 cccaatgtgg caaatgctac tgatggaaat gattttgatt tgcggcaggt gcggaaaaag
     8521 cggatgacaa tttatttctg tatttctggt gataatgcca ggttggctga aaaaataaca
     8581 aatattttct ttcagcttgc tatacaggtg aatcttgaaa agatgccaac ggatgatccg
     8641 gaaataaagc atgactgcct ttttctactg gatgaattcc cgtcaattgg tgctgtagat
     8701 tacatcaaga gtaaatctgg tctcattgct ggttacaagc tgaaattgtt gattgtttac
     8761 caggtcggct ctcagcttga ggaaatctac agttatgcag gcagtaaaac attactggca
     8821 agtgcaccct gcaaaattgt ttattccgct tctgatgtta aagatgcgcg ggagttatca
     8881 gaagcgatgg ggacacgaac agtaactatc ggttcgaaaa gcaaaagtcg tagtcgtgga
     8941 ggaacatcga gatctgaatc agaaagcctt attgagcgtc cactggtaac aacaaatgaa
     9001 ctacttacac tgaaatttag tgaagaaatc ctggcaatga agggagaaaa cccgattcgt
     9061 tgtgaaaagg cattctacta tctcaatgag tatttctttg gtgactttgt gaaggttgct
     9121 ccggaacttg caaacatttt ccccaggaag aaaggaaagc tggttatgcc tccacagaaa
     9181 gtatttgaaa atgaaatcgt cgcaaaaggg tatctggtag taaaagatgt tcctgatctc
     9241 gataaagcgg cataaaggag aacatgatga agaagttagt gtttttattg atttccattc
     9301 ttgctggttg ttcatcaccg ccagagccaa cacccgtgca gtttgaaaag gcaaatgaag
     9361 tgatcaatcc ctcattgcca tatgtccccg attttcacgg tgtcataaag tcagacgtta
     9421 gcggtaaagg atgggtttat gagatcactt ccttatccgg agtacaggcc agaacgccga
     9481 cgttttatta cgctctggct catgcggaca ggattgtagt gacaacacat gatgctgggc
     9541 tgtggtttcg aatcagagat ctgttgaaga tggaaggggc aacagcagtc gtggaatggc
     9601 gaaacgagaa aagtttttta cctgaacagg taaaaatagt tttcattaaa gcacaaaatg
     9661 aggtgaaaaa tgactggaaa aaatagagtg gttttaccag ccttgctggc gttaggatta
     9721 atatcaacaa atgctaatgc atctgaccct tgcgcttcgg tactttgctt atatggaaaa
     9781 gcagtcgggc aaggtggagg gagtgaatgc agaagtgctg aaaaggattt ttttaatatt
     9841 ctgaaaaaga aaaaaggaag cattcgctgg agtaaaactt ttgatgcccg taaagcattt
     9901 ctgaatcagt gttcaacggc tgatcctgct gctatatcaa aaatcatgag taagtttggt
     9961 cgtgtcagag gttaattaaa acctgataac cgcgccaacg ggtatcaggg tactgcaagt
    10021 atcacatttc gcgccaacga aatgtgatga ttagttacaa tcactgaggt tagaaatgaa
    10081 agtaaccaaa tctattatag ctattttatt gtgcttatct gctggtagtg cataagtgga
    10141 tgtaataaaa aatgctcgtg cctttttgaa aggaaccctc gatctgagcg ttcaggaagc
    10201 agatgaagat atagaggaaa gggaagaact ttataaaaag aacggggcac aacctgacta
    10261 tttaagttac ctggaggatt aacacatgca atatgcattg tttgatggat ttgaacgaaa
    10321 gtttttgctg gatgctcttg aattcggtgt tctgaaggac tggaaagaaa atccggtaaa
    10381 agaacttcct gatattgatg aatctgctca ccccttccat atctgttatg gtggatattt
    10441 attaaaccct ggtgtttcag attcagatat tagcagaaaa ataaaagacc aggcaggatt
    10501 ctggctggca gctattgatg atacccgcat ggattgtcat tcaatagctt attatgatat
    10561 tcacacactc cctctgattt cgtgtggtca tcaaaagata gttccttttg ccgcgttaat
    10621 aaaagctgat gaatgcatca tttcaaaaat tgcttcgtat tctggttttg ctgtaacagc
    10681 ctttttgaga attaaagagt gggatattgc aactaatata cttaaccgtg agggaatttt
    10741 tgcctttaat ggctgtgagc gcagattcag agtagtaagt aaagataact ggcaacatac
    10801 agtatcggaa gaacgcgcta tccgttgtgc caaaagatta attcaatgta aaggataaca
    10861 aaatgagact ttttatcgca gaaaaacccg cagtagcaaa tgatattgtt aaggcacttg
    10921 gtggcaattt tacccgccat gatggctggt ttgaaagtga taacgccatt gtgactaact
    10981 gttttggtca tattatcgaa tcacaaccgc cggaaaacta taatcctgaa tacaaagcct
    11041 ggaaggttga aacgcttcct ttacgtcttt atcccgtgaa gtatcagcct gttgaaagtg
    11101 cagcaaaaca ggttaaaacg attctcgaac ttatcagacg tggagacgtg actgaaattg
    11161 ttcacgctgg cgatcctgat gatgagggac agctactggt tgatgaagtc ctggaatatg
    11221 caggcaacac aaaacccgta aagcgcgttc tgattaacga caacacgctt ccggcagtga
    11281 aaaaggcact ggcaaatctt aaagacaatc gtgatttcaa aggactttac cttaaggcgt
    11341 tggcgcggtc agttgccgat gccgtctatg gcttctctat gacacgtgcg tacaccattc
    11401 cggcaaaagc cagaggatat cagggcgttc tgtctgtcgg gcgcgtccag actcccgttc
    11461 ttggcctgat tgtgaatcgt acccgtgcta accagaacca taaatccagt ttttactaca
    11521 ccatgaccgg agtctttcag cgtggtgctg atgttatcag ggcgaactgg aagccagggg
    11581 aatttgctcc gctgacagac cgtaaattac ttgataaagc gtgggcagac ggaacggctg
    11641 catcccttgc aggaaaaccg gctacagttg aagcagcagc aactgatgat aaaaaaacgg
    11701 ctgcgccgtt gccgtttaat ctggtcagac tccagcaata catgaacaag aagtttaaaa
    11761 tgacggcaca aaaaacgctg gatattacgc aacaactacg cgaaaaatat aaagcaatta
    11821 cgtataaccg ctctgactgc tcatatcttt cagatgaaca attcagcgaa gcgccgcagg
    11881 ttatcgatgc cctgaaatca gtctttcctc agtcgctgga tattgattct gcacgtaaaa
    11941 gcaaagcgtt taacagtgca aaggtgactg cgcatactgc gataatcccg accgccagtg
    12001 tgcctgatgt taacgcactc agcaccgacg agcgcaatgt ttacctggcg atcgcacaac
    12061 actatcttgt tcagttcatg cctgaaaaag cataccagga agtatcggtt gccattcagt
    12121 gtggtgatga gtcgttctat gcccgtgcca gaaaaacaac tgacagcgga tttgaggcgt
    12181 ttcttggcgc ggaaaccaca gacgaaggtg aatcagaaga taatgatgat tccgcttttg
    12241 aactgctctg taaaattcgc acaggagaaa cactgacgac aaaagaagtt attgttaatg
    12301 agaagaaaac aacaccgccg ccgttattca ccgaagcctc cttgcttgct gcgcttgttc
    12361 gtgtcgcgga ttttgtcact gatccaacaa ttaaaaaatt gttgaaggat aaggataaag
    12421 acaaaaaaga tgaacatggt ggcattggta cgccagctac ccgcgcagcc attctggaaa
    12481 cgctgaagaa aagaaactat atcacgctgg aaaaagggaa acttattcct actgataccg
    12541 gatatgcgct tattgatgcc ctgcctggta tagcggttaa tcctgatatg acagcattat
    12601 ggtctgaaaa gcaggctgcc atagaaaatg gcgacctgac ggttgaacag tttattaatg
    12661 atctgtacgg tgaactgaca ggcatgattt ctgatgttga cctgggcgag atgaagattg
    12721 aacccgctgc gccagcaggg cagtttcaac gcctggactc tccctgccct tcctgtggta
    12781 aacatattgt tatcaggccg aaaggttatt tctgtaccgg atgtgaattt aaaatctgga
    12841 gtgagttttc tggtaagaaa atcacccagg cacaggccga aaaactggtt aaatcaggga
    12901 aaaccgattt gattaaggga tttaaaaaga aaagtggtgg aacgtatgat acagttcttg
    12961 tccttgagga taagaaaaca gggaagctgg gttttccggc aagggctaag aagtgaaaac
    13021 aaagcaggaa tggctttttc agttaagaaa atgtacatca agagatactc ttgaaaaagt
    13081 tattgagatt aaccgttaca aactgccttt atcagaatca gaggcatttt attctgccgc
    13141 agatcatcgc cgagcagaac tggtgatgaa taaactttat gataaggtgc cttccggcgt
    13201 ctggaagtac gtacactaaa taagaggatt aattatatga gcgaactgac taaagaagat
    13261 gaatacggca ttatcagccg tactatgatg aatattcgtt cattgcgtgt ttttgcccgt
    13321 gagattgatt ttgagcagtt gctcgaaatg caggaaaagc tcaacgttgt tattgaagaa
    13381 cgtcgtgaag atgctgaacg tgaagcggct gaacgccagg aacttgaagc caaacgtcag
    13441 caggccattg aatacatcat atctttaggt cttgatcccg aatcactcct tgctcctgta
    13501 acagcagata cagtaaaaac caggcggaaa gccaaaggcg gagtaagaaa ggctaaatac
    13561 cgctttaagg atgaaaatgg cgagatcaga gaatggtctg gtaatggcaa gcgtccgctt
    13621 gctttacaga agctgcttga tgaggggcat ttcatggaag atttcctcat tgagaaaact
    13681 aagccggaac aggcagaata acccgccaag tatacatcac acagggcact gttgcaaata
    13741 gtcggtggtg ataaacttat catccccttt tgctgatgga gctgcacatg aacccattca
    13801 aaggccggca ttttcagcgt gacatcattc tgtgggccgt acgctggtac tgcaaatacg
    13861 gcatcagtta ccgtgagctg caggagatgc tggctgaacg cggagtgaat gtcgatcact
    13921 ccacgattta ccgctgggtt cagcgttatg cgcctgaaat ggaaaaacgg ctgcgctggt
    13981 actggcgtaa cccttccgat ctttgcccgt ggcacatgga tgaaacctac gtgaaggtca
    14041 atggccgctg ggcgtatctg taccgggccg tcgacagccg gggccgcact gtcgattttt
    14101 atctctcctc ccgtcgtaac agcaaagctg cataccggtt tctgggtaaa atcctcaaca
    14161 acgtgaagaa gtggcagatc ccgcgattca tcaacacgga taaagcgccc gcctatggtc
    14221 gcgcgcttgc tctgctcaaa cgcgaaggcc ggtgcccgtc tgacgttgaa caccgacaga
    14281 ttaagtaccg gaacaacgtg attgaatgcg atcatggcaa actgaaacgg ataatcggcg
    14341 ccacgctggg atttaaatcc atgaagacgg cttacgccac catcaaaggt attgaggtga
    14401 tgcgtgcact acgcaaaggc caggcctcag cattttatta tggtgatccc ctgggcgaaa
    14461 tgcgcctggt aagcagagtt tttgaaatgt aaggcctttg aataagacaa aaggctgcct
    14521 catcgctaac tttgcaacag tgcctcacac agacatacac ataggtatgt ctgtgtgaca
    14581 tacctatgta cagtgccaga tggcgttgct acgtgaaaaa taacctaccc tacccctgct
    14641 tttttcgcag attttacgta gcacaccgtt gctatagcat tcatctaaaa agctgaatgt
    14701 ccttttctgt cgctgttgca ttttaattca ctgaaaaata ttgagtaatg aaaatgccgg
    14761 taacgcgtca agctgttggc caacgcgaca ggcagtattg gaagcaacaa aaaaaatgaa
    14821 agaaaaatcc ctcaaatgaa ggagaaaaaa cggaactaca gccgaacgac aggcacaaaa
    14881 aaacccgact ggtaatcggg cttttttgcg ttttccagtc ttgagttggt ggctctgacc
    14941 ggagaaggtt actctacacc taacgtttac attttattca ctatggtgct gtaaagcaac
    15001 taaatgtggt taaggaacca catttagtgg tgtaacgggt gttttgtgta gcgtataatc
    15061 agtcagttag tcatgtagtt ggcttgcaat cctgctgttc ccgtatctgc gggtatgaac
    15121 gattttaaag tcctggctgg ataaacaggt ggtgctgtat tcggtgctct ggcaggagga
    15181 ggtcactcta cacctaacaa tgcgagagag ccgttgtgac aggcagtgta tgagcaagca
    15241 acggtgattt cctccagttt tactggagaa acggatgatt aatatgttaa tcatcgttct
    15301 cagagctgtg gtcgccgttg caaacgcgct gattgcagtt ctggaactga tccgccaatt
    15361 catcgattga tgacaacgga aacgtaacta agggcaggaa gtgaaccgct tcctgccctt
    15421 taacaaaaaa ggaggattta tggattttat gagcattttg gggcgctgtt tacttcttcc
    15481 tttccctgtt gcgatgtttg tcggttgcct gtttcctggc atcgatgatc gcttatccgg
    15541 aatgcttatg agtgttgctg tgggatgttt atcgtggtat gtcaccagac cgaagaaccg
    15601 acagacaaag gccgcgtaag tggcctttaa ttgggatacc ctttagttac aacattctaa
    15661 tagctcattc catcctccgc tcatccagca aacataacct ccctgcccct ccccactaca
    15721 gaaagtggcg cgccccgccc gtacgggcgg aatctaatcg cttaattttg aatgttgtaa
    15781 ctaaacatac tcattgctgt attgccacaa ggtttcgcag caagggagga taccgaaagt
    15841 aacgctgtca cttttgcttt caagtgacca accaacgggt acatcacact gacatacaat
    15901 aatgtatttc ttcatgatgt acatcattgt aattcattgt gacatacact atagtatgtc
    15961 catgtgacat acgcatgcgt acatcacata gaaatacaca tgagtaaatc actgtgacat
    16021 acaaggggta ctatgattat cgtaatcggt ggtgataaag gcggtacagg taaatcacat
    16081 ctggcaacca acttaactgt ttgcctctca caacagggaa agagaacggg gcttgttgaa
    16141 acagacctga atggctcgac caaaaaatgg aataaacgca gagaacaggc cggattaccg
    16201 cccgtcgcat taaatgaagc ctatggcgac atcagtgcca aaataacaaa aatggcagat
    16261 gtagcagaaa tcctcattat agatactgcc ggatatgaca gcacggagtt cagaactgca
    16321 ctaaaagttg cagacattgt gattgtcccg atcgacccgc ttgcccaggt ggaagcagac
    16381 agtcttcaga ctgtgacaaa aattgtcagg gatgcgcaaa aaataaatcc caggctggct
    16441 gcacatgtgc tcctgtataa atgccagcca aatacgttca gtgaacaaca agaattaaga
    16501 gactctctca acagccatga ttactggctt aaaccaatga aaagcacggt ttcttttctc
    16561 cgggcctttg taagagcaat gaatcaggga atgggggttc acgagttaaa aagtaatgtt
    16621 agcggtgcca gccaggcaaa agcacaaatc gaactcttgc tgaaagaact ggaactgtaa
    16681 atcatagtga catacactaa tgtacatcat catgatatac attagtgtga aacaatcaga
    16741 ttagaaggta catcatggca aagctggaac taccagaact agaacaaaac caggaagtga
    16801 acgccacaaa atttgttcag gacgcaggaa aacgccccac agagaacaaa acaaaactgg
    16861 cttcattccg cataccgaat gaattgcttg aattcattga taacgaatca aaaagactgc
    16921 atcgtcccaa gacaaaaata atcaaagcag cattactggc ttatcaggat ctggacgaaa
    16981 acgaactcat taatttgtgg ttcagagctg acagaaatga ttaatcatag caagtggccc
    17041 aataaactct ttatcatttt cttttagata cttatctgaa tgtactaact tcatcacttt
    17101 taaatgtagt tgtgattcat ttttagttac tcttgcaata aaataccctt gtacagttgt
    17161 tgcacgggta tttaggagca ctagatgagc cttatcgatt taagtttatc aggattatca
    17221 gaaccaggaa caaaacttat tgaaaaaata agtgatgcta ttggtgtgct ttatgaacct
    17281 acaagaatca ggaaaaaagc gaaggctgaa gctgaagcta aacgcacaga gctaatttct
    17341 aggttagagc ttgagggaat agaaaaacgg gcagttgagc gttttctcaa acgtgaaacg
    17401 aaacgacagg aaaacattga aaatataaca atgcaagcag cacaaagtct atctgagagt
    17461 gataatgttt ctgatattga cgaagattgg atagaggctt tcttcaggga gtgtgaggat
    17521 attagtgacg aacaaatgca aatgctttgg ggaagaattt tatccgaaga agcaaagtca
    17581 aaaggttcgt ttagtcgtag aaccttaaaa ctattatcca ctataagcaa agaagaagcg
    17641 aaccttatta cttattttgg aaagtttgtt tggcaggcaa acaaactcac tccaatttta
    17701 tttaccgatg agaatggaga tactgaaggt ataactttcg ataaactttc ggttttagac
    17761 tccttaggcg ttattcaaca aggcattggt tatagtttaa gatacaaatt ataaatactc
    17821 tcaagtgtat attcagtatg ggattgcgca atgattgcct aataaaattt ctgaaatatt
    17881 tctgtatcgc ataatttttt atatcagata aattgtactg gatttcttaa aaaattgcag
    17941 tatgattgcc gcaattatcc caccgtttat tttttgagta gtttctcatg atgcagcata
    18001 cttctgtgtg gtaccgacgc tcggtcagtc cgtttgttct tgtggcgagt gttgccgttt
    18061 tcttgaccgc gaccgccaat cttacctttt ttgataaaat cagccaaacc tatcccatcg
    18121 cggacaatct cggctttgtg ctgacgatcg ctgtcgtgct ctttggcgcg atgctactga
    18181 tcaccacgct gttatcatcg tatcgctatg tgctaaagcc tgtgttgatt ttgctattaa
    18241 tcatgggcgc ggtgaccagt tattttactg acacttatgg cacggtctat gatacgacca
    18301 tgctccaaaa tgccctacag accgaccaag ccgagaccaa ggatctatta aacgcagcgt
    18361 ttatcatgcg tatcattggt ttgggtgtgc taccaagttt gcttgtggct tttgttaagg
    18421 tggattatcc gacttggggc aagggtttga tgcgccgatt gggcttgatc gtggcaagtc
    18481 ttgcgctgat tttactgcct gtggtggcgt tcagcagtca ttatgccagt ttctttcgcg
    18541 tgcataagcc gctgcgtagc tatgtcaatc cgatcatgcc aatctactcg gtgggtaagc
    18601 ttgccagtat tgagtataaa aaagccagtg cgccaaaaga taccatttat cacgccaaag
    18661 acgcggtaca agcaaccaag cctgatatgc gtaagccacg cctagtggtg ttcgtcgtcg
    18721 gtgagacggc acgcgccgat catgtcagct tcaatggcta tgagcgcgat actttcccac
    18781 agcttgccaa gatcgatggc gtgaccaatt ttagcaatgt cacatcgtgc ggcacatcga
    18841 cggcgtattc tgtgccgtgt atgttcagct atctgggcgc ggatgagtat gatgtcgata
    18901 ccgccaaata ccaagaaaat gtgctggata cgctggatcg cttgggcgta agtatcttgt
    18961 ggcgtgataa taattcggac tcaaaaggcg tgatggataa gctgccaaaa gcgcaatttg
    19021 ccgattataa atccgcgacc aacaacgcca tctgcaacac caatccttat aacgaatgcc
    19081 gcgatgtcgg tatgctcgtt ggcttagatg actttgtcgc tgccaataac ggcaaagata
    19141 tgctgatcat gctgcaccaa atgggcaatc acgggcctgc gtattttaag cgatatgatg
    19201 aaaagtttgc caaattcacg ccagtgtgtg aaggtaatga gcttgccaag tgcgaacatc
    19261 agtccttgat caatgcttat gatgccttgc ttgccaccga tgatttcatc gctcaaagta
    19321 tccagtggct gcagacgcac agcaatgcct atgatgtctc aatgctgtat gtcagcgatc
    19381 atggcgaaag tctgggtgag aacggtgtct atctacatgg tatgccaaat gcctttgcac
    19441 caaaagaaca gcgcagtgtg cctgcatttt tctggacgga taagcaaact ggcatcacgc
    19501 caatggcaac cgataccgtc ctgacccatg acgcgatcac gccgacatta ttaaagctgt
    19561 ttgatgtcac cgcggacaaa gtcaaagacc gcaccgcatt catccgctga tttctccctg
    19621 tattttttcc aaacccaccg cacactccat tcgtattatg ggcggtgggg tggggtttgt
    19681 tatgccgtat ttatcaaata aacgcctact tgctgagatg agtatcgctc ttgtcatggc
    19741 gatcgttgcc acgctgaccc ttgagcacag tcagattgat ctgatggtcg ctgattggtt
    19801 ttatctgggt atggggcatt ggatggttgc caagcaagct tttttgccag atttgctact
    19861 gtattctgga ctaaaaaagc tgctgatggc gatgctgatc tacttgctgg ttgcgaccat
    19921 ttgccgtgct tatcatgaga aaaagggcaa tgctatcact gccaagtggc ttgtcccagt
    19981 gacaaaattt cgcgtgcgtg agcttgcgta tctggtgctg actttgatcc tagtgccgac
    20041 agttgtcgcg tcattgaagg catatactca tgtggtctgc cctgtgcatt tgacgatttt
    20101 tgatggtacg ctgccgtatt tgccgatgct tgatagtatg cgtaacacca ttcctgataa
    20161 gtgctttcct gcggcgcatg ccagtagcgg atttgcgctg tttgcctttg cgtttgcgcc
    20221 aagtttgcgc cgccgtcgtg gtgcgatcat catcgtggtg atggcattgg gctgggcgat
    20281 gggctgctat aaagatgatt attggcgatc attttttgag ccatacggtg gtgtcgatga
    20341 tgcttgcgtg ggcgatgtcg gcagggcttg cgtgggtgtt ttttaagaag ggtgaacaag
    20401 tttaatcggc tttaaaagta aaaacggtcg tatcggttat tacggaacgg ttttttcagt
    20461 tgagtttcaa agcgatgatt catcaacctg gaaactacca ataggaacgg ctttacttac
    20521 gcctatcggt caagaattga tgaaaatatg cggttccact ccagatattg cgtatttaaa
    20581 taaattcctc aacaaaataa atgttgaagg aagccaggta aaactatcaa ttattaatat
    20641 gtaaagaggt cgagttacct gtctgagttc cactaaccat aattaaaagc gaccgcaaaa
    20701 actgcccagt gaaaactgtg ttgccagtaa tcacaaatgc agcaagtact aataaagagc
    20761 ctgttaagcc cgcaaatatg tgggcttatt tttaattact cttcatcatc ccgcaggaac
    20821 tgacaaaaat cttcgctccc catcatatcg acagtgtttt taaattcgaa aaaagaaatt
    20881 cctgtcatag cacacacgcg ctggataatc agttttttct tttgctgtct gacggttgcg
    20941 gtttcaccaa actggataac agccaggact gtttcatcat atgatttcag gacaaaatca
    21001 caggttatat tctgcacttc acggattaaa tcttttacag cttcctcgct accatgagga
    21061 cgaacaaatt caatgagccg tattttggga aaaacggaat aatcaggtat aatattacgt
    21121 gaaagaatgc ctaaaaactc tgattcatta tttgagagta agggtacttt agtaaaacaa
    21181 tcaacctccc caatggctgt aaaagcattg gttgtcaaag ctggattgtt cttaataaaa
    21241 tcagagaata cattttcagc tgatggcaaa acaacagcag aattatgttg ttcatctcgt
    21301 tttttattac ggttaaatat catttcatat tccttttaaa agagcctgcg gcaggcacag
    21361 gcaaaaacat cgtttttgga caatctgatt caaatgttaa catttgacat cggattgtct
    21421 atcctgcatt gttctttact gtctgtaaga tcggcgctca ttcttccggc gttctcccga
    21481 taccaaaaag acggaacgca aaacggcttt cgatccacca ttcaaaaatc tgctctgcgc
    21541 aaccacaaac agttaaggcg atccatgcag caagaacaac gtaactactg acatctgcac
    21601 ccatgtacca ggcgatagtt aaacccatca ctgcgatacc gcctaaaaac tgcaacaaga
    21661 aacgaaatcc cgcaagaatc cccaatggaa taacaacaac cagataaagg gaagcagcca
    21721 gaaggtatct gacaggtgtc agcagataaa agaacctgga tattttcttt ttgtcagaat
    21781 aaacggcatc atttgcaaca tcggttgaat gatcattcat gctgtccctg attctttgaa
    21841 aatctacgat attatccttc atattgttat gacctcaatt ttcaggtggg tacattttat
    21901 caaacatatt agtaaactct gagtcttccc tggtatcgcc ctcataacca attgtataag
    21961 agaactttaa tttataaact tttctcccaa ttttttctga aactacgaaa cttaagttct
    22021 ttacttccgt atgtttcatg atttctttta ctgatttatt aagaacatct cttttaaaag
    22081 caggataatc tggatactta taatccttca ccccccccgc ccctattgta taaagattca
    22141 attcatcttt aagttcatct attgtcattt caaaactatt cgcgcgagaa ttattactat
    22201 atattttacg aatgagttga tatagtgatg cagcattaac acttgtcagt cgaacaacag
    22261 ataataaaac ttgcgttgta taacgttttt cttcaccaat aagtttacat aaaaatcttt
    22321 tcgcttcttt cgtaaacttg atccccactc taccttcatt cctgtaataa gtagaaaaaa
    22381 cagtcagact caaattcatt gaatcaggta cattactttt agtgaactta aatcccaaat
    22441 cactactcag ttctaatatt tcatcatgtt tcagcttaag aagcgtcgta tctaatatat
    22501 tagagccatc cctcaaagca agataagccg catcaggctt aacctgaacc catttaatgt
    22561 aatcggcaac tgtcacataa aatatgtgat catcatcgaa ttcattttta gagtttatct
    22621 ggcacatggc taaaaataag acttttttag cagccatagg caatgttgac agcgttgaat
    22681 tcaattcatt tcgatgtctc acttttgtta agcgagaaag ggaagtctta tttgtcgtca
    22741 ttctcattgt tccaacactc ttgataatca gactttaaca ccagaaacat gatattacaa
    22801 cacaatcaat atcatgttta accgagtatc ttctcatgtt tcatatctgt gatttatctc
    22861 acaaaggtaa tccatgctca aaatccacac tggattcaag gcagattaac aacagattca
    22921 aaatagattc accagaaaga acaacgaatt agtattctta tgacacattt tgtggatatc
    22981 accgaggaag ctctcatgtt taaccgagga agctctcatg tttaaccgag gaagctctca
    23041 tgtttaaccg aggaagctct catgtttaac cgaggaagtt atcatgttta accgaggaag
    23101 ctctcatgtt tagacaaaaa acacgcttaa aatcaataaa ttagagctac tctaagtttt
    23161 taagttttta agaaaaacaa gaaaagataa ggcttttaat gcgtgcgaat attcaggaac
    23221 tgtggataac tcaacaaaac cagcaacgat gatggttcct taccataaat ctgtcccctg
    23281 atgattatta cccgcaagct aaaacaaaca tcatcaatca ttaaaactca taactttcaa
    23341 taacataaaa tcatcaaaaa aatatttgat gccttatgta tctcaatttt caagaccata
    23401 aatttgtccc tagttaactt taacttattg aaataaatat aatattcgtg cgtactgatc
    23461 ctaatgtcac atcgcaaaaa ttccgcttcc tcgctcactc agtcgctacg ctcctgccgt
    23521 tcggctgcgg cgagcggtat ctcctttctc aaaaccagag agattcagat catatgatcc
    23581 gttatttgat cctttttgga tcttccacta agaagccctg aatcgcgctc tgccgcttcg
    23641 ttcgatacaa ccatgaggaa aaccatgcga aatgaaaaaa atcgcttaaa atgcgattca
    23701 gagcgtttta gggaggttct gttagttctc ctgcattgcg cccgtagttc gctaacgctc
    23761 acacgcgcag tacagcgccc cgccatgctg caatgcacca gggcggggta aactcgcttg
    23821 cgctcgcgct aactgcggca ttctgcggcg caaatcagca taatcatggc ctgctggtca
    23881 gttgggcttt gcagggtgaa gggatggcct gtgcaccctg gtacgttcgt cagcggctgc
    23941 gccgcgcttc ggggcgatgt ggctcctgtg ctgccctggt attttcgttc gccccttcca
    24001 tccgcttacg cggattaaaa aacgtgataa caatcactta tcgagtaaaa aaacgggaga
    24061 aaacttgcaa atacgactta aaggtcgtat tattgtttca tcgaaagggg aatggcccct
    24121 ctcacaatag cccagcaggg caggagatta aaaaaatgaa tatccaggaa gcattaaacg
    24181 tttttggatt atccggcgaa ttaactgaaa aagatatcaa agcagcatac agaaaagccg
    24241 ctttaaaata tcatccagat cgtaacccgt taggggctga actgatgaaa gcggtaaatg
    24301 cagcttttga tgtattgatg gcaaatattg ataaaataaa tcagttccag agcactgatg
    24361 aacatgcacg atataattac ggtgatgacc tggaaaaagt attaaacgtt ctttctggtt
    24421 tatctggtct ggtatttgaa gtgataggta actgggtctg gattagtgga gaaaccatta
    24481 cacataagga aactttaaaa gaaatcgggt gtaaatgggc ggcaaagaaa aaacaatggt
    24541 tttatcgtcc agacgaacat aaaagttact ggaatcgtga agaacacacg atagaagaaa
    24601 tccgcgcaaa atacggtaca accggacagc gcagggcgac agggtggcaa cgcgtggaaa
    24661 ccagagcgta accagaacgg gggcgagaag cccccgatat tatagccagc ccgtcttttg
    24721 gggcatcgaa cccaaaaaga cgggaacagc agccacgtag caaaaaggga aacagatgaa
    24781 ctcttttttt gaacaatatc accctgtctt tgaagttgtc tgccgtatcc tggggaacgg
    24841 ctggcgcgtg aacaaacttg atgattgttc gtctcgtata aaactgacgt caccgcagtt
    24901 taaaaattac tctgtgcata ttcggatgga aaaagaccgc ttttctgtgg tggggagtgt
    24961 ggatagtcgt tcctggcgta gtccgcatca tgtttgcacg ttatccagaa aacggaatcc
    25021 cgttgatatt gcagccgata tcgagcgaaa aattctggta aatgcttcgc aggaggtgtt
    25081 acaggcgatt gagtatgaga aacaccaggt ggaaaaaaag gacgaaattc tgatcctgaa
    25141 aggtatgtta tcgcaacttg tccagcttga aagctggtat ggggcattga caggctttaa
    25201 agctgaaaac ggattgaacg gtaaagtcac cgaacagggc gacagttatg atttacagat
    25261 tcggggcttg agtatagatc aacttgttaa aattacaggg tatttgaaac agttatgaga
    25321 aaaaataaag gtgatgtgac ttattttctt gaaaaagaag gtgacaatta caggcttaca
    25381 aaaaggataa aagccagaac aaatgttaaa atcgggaaca aaactacgaa aattacattg
    25441 tatgatgctg tactgaatga gaatgaatta caacatattg attttacgtg tgccggatta
    25501 agggaagacg atgagacgcc agttaagaat ttaattaagg agtttatgtt aaatgaaacc
    25561 cgataataca cctgaaaatg taaaaaaatt acgtttaaaa gcaggattaa cacaaaagga
    25621 atgcagtcat atttatggtg ttgggctaag aacctggcag aaaaaagagg aagttaatac
    25681 tcaaaacagt caaagtctgt cactggttga gtttgagttt cttttgttac ttgcaggaga
    25741 acatcctgaa tacgtgctct gcaaaaggga gtcaaaataa aatgacctgt gatggtttta
    25801 tattagtacc tggagttgcg ctcgtagctc gctgacgctc acacgcgcag tacagcgccc
    25861 cgccatgctg caatgcacca gggcggggta aactcgcttg cgctcgcgct aactgcggca
    25921 ttctgcggcg caaatcagca taatcatggc ctgctggtca gttgggcttt gcagggtgaa
    25981 gggatggcct gtgcaccctg gtacgttcgt cagcggctgc gccgcgcttc ggggcgatgt
    26041 ggctcctgtg ctgccctggt attttcgttc gccccttcca tccgcttacg cggattaaaa
    26101 aacgtgataa caatcactta tcgagtaaaa aaacgggaga aaacttgcaa atacgactta
    26161 aaggtcgtat tattgtttca tcgaaagggg aatggcccct ctcacaatag cccagcaggg
    26221 caggagattt aaaatgaaat gctcatctgt ttttacttca accactaatc atgttttcac
    26281 attcgaacga gtaacgcttt gcactattat ccttatgcat aaggatactg gacaacagta
    26341 tgttgtcata tttactgata acaataaaat tcgtgactat aaagccggaa ttgttcctca
    26401 gtttggcgaa cttaagcaga gtgatgttga tttagtcctt ttctacaggg acgaatatga
    26461 aaaatatttt gattcattaa aagatggcga tgaatgcttg agttttaaag attttattga
    26521 gtgtctttgt taagcattat gaatgcaggg gcatccctgc attttctgga aatttcaata
    26581 ttgattctga aattgtctat taacatcaat gcaagggaaa ttcatgaaaa cgttaaaaca
    26641 agccgcaatg cagtttgcat ctgatctgcg taataatcgc tgttttaaag ctgcttataa
    26701 tgatgctctg ttagagcttg atcgggaaga tttaaacgcc attgtacaat gcacatttct
    26761 ttttgagcca aaacgaacat tagccgaact tgataaatta attaaaaaga tagaagtaga
    26821 agaagattat gagttttgtg tatcccttga taaaggtaaa ggattacacg aagtcagaac
    26881 atttaaaagt gagcgtgagg cgttggatgc ttatcgcatt ttgactcttt acggatacac
    26941 agtaactata gaaaagaagg agggtaatga ctgactattc aaggtgtgat caggttgttc
    27001 caccaacctg atcacgttat cgacaatcaa aactgaatga ggtttttaaa tgtcaacgcg
    27061 gcagatcgta cagcttgctg attcccttgt caaaggctgg gaaaccagaa ttccggcaat
    27121 gaaatttagc gaatgggatc aattccggtg gtggttaaac tacttgcaag ggtatgaaat
    27181 gttttaaata aaaaaagggg ctttctgccc ctttgtattt tttgacaaaa atgccatgtg
    27241 taactataat tagttgcata tctatagggg atggatttat ggggaaaaca gataagctac
    27301 tggcaaagtt tttaaacagt aaaaaaacgt ttgaatggga tgaactggtc gttttgtttt
    27361 cctctttggg atatgtcaaa aaggaaatgc aggggtcaag agtgcggttt ttcaatgctg
    27421 aaatcaatca caccatatta atgcatcgtc cacatccgga aagttatatc aaaggtggta
    27481 cgctgaaagc aattaaacag aatctgaaag aggctggatt attatgaaac atttaaaata
    27541 taaaggatat ttaggcacgg ttgaacccga ttttgaaaat aatgtcctgt atggaaaact
    27601 ggcgtttatt cgggacctgg taacttatga ggcttctaca ttagctgaac tggaacagga
    27661 gtttaaaaca tctgttgatc tgtatttaca gtcttgtgtg gaggatggaa aggaacctga
    27721 taccccgttt aaaggcgtgt ttaacgtcag gcttgatcca gaactgcatc gtcgggtagc
    27781 agaaatggcg atggaagaag atttatcgtt gaatgccttt gttaataagg ctctggaaaa
    27841 agaagtcagc aatcatcgcg caggggctta attgcccttg tttttatgcc ctgtaagggc
    27901 atgggaggcg ctttgcgccg gaagccccgc agcgcagcga ggacttaaaa agcgttacgg
    27961 cttcagccgt aacaattccc agccctgcca ggcctgtttt ttctttcaca aatctttcag
    28021 ctatacgttt gcctgatggt cgaagacgaa agaatctttc agcaacgaaa tctggacata
    28081 tgcagcgacg attttatagc caggcacagt gccacatatg gtacaatcaa tgcaggatag
    28141 acaatccgat gtcaaatgtt aacatttgaa tcagattgtc caaaaacgat gtttttgcct
    28201 gtgcctgccg caggctctgt tggggtgact tatgaagatg atagcgttca ggctaagtga
    28261 tgatgagtta aaatttgcag aacataacgc tattttaagt ggatttacca gtatcaatgc
    28321 ttttgctaag cataacgtgc ttaatattga aaccaagcct gttaacatcc cagttaataa
    28381 tgaaccagca aagctggtat cagtgcgtct ttaccctcat gaaatagaac ttgttaaacg
    28441 taatgctgct cttcacggca tgagcatgag cagagaaatt gctattcgtg tgcgtcagtc
    28501 tttgttaaag agtgaagtct gtctttaccc tgatgaagtt aaggaactta aaaaactatc
    28561 aactgctgta gatcgtgttg gtcgcaacat tcattttatc ataaaaggtg aaagattctg
    28621 tacggttaac gatccagatt tcagaaaaga cgttattgaa gtgattgaac tgtgtaagca
    28681 aattgattca aaacttgaaa cgttaaccaa gagtgttgtt aacagatttg ggtgatttat
    28741 gggtgtgtat gtagaacagg aataccgtat taaacgcgct aaagggactg ggcgtgatcc
    28801 gaaatctcct aagttatcgg gaagacatat acatgccagt aaatcggctt ttaatcataa
    28861 agtcagacat ggtgcggaca agaaagcata tacctggaca cctacaaaag aagtcacttt
    28921 taaaatcact ggctcaggta aaacagccgc aggcatcaaa aatggtattg attacattac
    28981 ccgtaatggt gaacttgagg cttactgtta tgatggaaaa ggttcagagc aaacagggaa
    29041 aggagaagac tttaataggg agtttacttc aactttatct aaaggaaatg attactccag
    29101 gacatatcgt ggagaaaaca tcgatcatgt gaaaaacatg gtcttttcac caccaccaga
    29161 agctggagta agcagggaag acgctctgaa agctacggta gaatttctta aagagactta
    29221 tccaaaccat gctttcgttg ccgtatacca tgatgataaa gaagatcatc ctcatgtaca
    29281 tgttaatatt aaacttcgtg atgaagaaac aggaagaaga ttaagactta ctaaatctga
    29341 aaccaggaag ttcagaaacg gttttcatag aaaactgaaa ggtatgggat atgatgttac
    29401 cgctacctgg aaaaaagatc ccgaacgtaa acgggagatt gagcgattac aggctgaaaa
    29461 tccgaaaaga ctccggaatg tttacaaggt ggtggatttt ggggagactt catatcagaa
    29521 taaggcaggg gaaaaacgaa cacctttcct cacttatgaa actttaaaag gtggaaaaca
    29581 ggttacgatt tggggtaaag acctgaaaaa tcatttcgag tctgaaaagc tccagccagg
    29641 aacgcttatc aaagtaaaaa aactggctcc tacgcttgta cgtagtccaa tgtttaatga
    29701 tgatggaact gttgcaggct acagggaaac gcatcgcaat aactggcaga ttgaaaatat
    29761 tgcccttgag cggaacagag aacgtcaggt tcatgagcgt gaaaccaggc agccggaaga
    29821 gagcgacgtt aaaaagcagc tatccagaaa acatgagcaa ggtcacaata tcgggtttgc
    29881 tcttgaacac gggtttacaa aggattcaga agaacataaa aaactaagaa tacagcaaga
    29941 gaggaactgg aaaggcctgg gattttaatt tgattttggc gcaggtgaac aaagcggcta
    30001 ctttgctcac ctgctgatca caacaaccta cgagggaggt tatcatgact gagcatgatg
    30061 ctatctgcat ttctggactt catcaaattt ttagtgatga agaacatttg agtgagcaac
    30121 aaaaagacat tattctgatg tacgcttatg gctataccct gaatgaaatt gctgatttca
    30181 aaggactaaa gccttcaact gtcagaaaat atctcgattc tgtaagagct gaactgggag
    30241 gtgtctcgtt ggcagggatc agaacactgg tactcattcg gactaatgcc cttctcgtgt
    30301 caagtctttc caggatcagt gagaggggga atttatgaaa aaatatctgc tttttgcttt
    30361 gccgttcttc gttgttggtt gtagtgaaga agtaaaaagt gtggattggt gggggcagca
    30421 tcttacggaa gctaaacaaa agcaggcaga gtgtgagaag tctggctctg attctcagaa
    30481 ctgtaagaat gttaaacaag cattgtttat tcagtctcag aaggatgctc cagtccctac
    30541 attcgattaa ctaatgtttc aatcatacta gagcgcccat atgggcgctt ttttttgcat
    30601 gatcacacga atcataatat gaccattttg tcaatgttat ttgatcgtat tgttgagcat
    30661 tgttattttg cgaatcatgt tcgcatctaa aacaaatcca aaacacactt atagtggatt
    30721 gattaaatga aggagaaatc agataagtca tcggaaaaag gggtttatgt cacgataaaa
    30781 ctcgatccca ggttgaatgc atttatcgaa gagaaaacga aaacatcttt gcttagtaag
    30841 aggaagcaaa ttatttactt attaatgcag agtatgcgta ttgatggata tatggagcgt
    30901 tagctatggc gtctttattc ccagccttgt tgctgtgtgc ggcgtcagtt catccggata
    30961 cgataaatga tattgcacgg gtcgagagtg gcttcaatcc ttatgctgtg gctgaaatta
    31021 ttcctgaaag ggaacgcggt agctatggca aaagtgttat cagtcatatg cccaaaagta
    31081 aggaggaagc tctaacagtt atcagagaaa ttgaaaacag aaaaagacgt tattctgtcg
    31141 gattgatgca gattaccagc agtaattttt ctttttattc cacgtccgca gaaaaactcc
    31201 ttgattcgtg tgaaaacttg tctgttttcg aaaagattat cgtggattgt tataaacgag
    31261 ggaggagcct ggagaatgcg cttagttgtt actatacagg aaattttagt aacggtaagc
    31321 gaaaagaaaa agaatttaat aatacaagtt atgttgagcg aattggttat acagggaacg
    31381 aaaaaaaata tgttgtacca ggtacaagaa gcaacggggg agaacagcga aaaaatcgtt
    31441 cacacaatgc gtcagttatc tggcccgaaa ccattctgaa atctgctttt gttgataact
    31501 cacatccaac aaaagttatt aattaacagg acttataaaa tgtcatttaa gaaatcagta
    31561 tgtaatcgta tcagttcatc tgtcactgct gtaatgcagc gtaaaaataa ggtagttatg
    31621 gcagtcgccg gggcaacagt tgcatcaccg gcctttgcgg atggattttc aaaagcggaa
    31681 acactgctgg aaaaggttaa aacagggctt agtggccttt cactggtcac ggtgactatt
    31741 gcctgtctgt gggtcggcta caaggttctg tttggtggaa gcacgattcg tgaatgctca
    31801 cctatcatca tcggggcaat tgttatcgcc agtgcggctg aagttgcatc aatgatggtt
    31861 aactaataaa gcggggacga tagtatgtct acactttata aagcgatgac acgccctgct
    31921 atgtatgtgg gtgttcctgt cgtccctctt actgtggttg caggggcgtt atttctggcg
    31981 ggggtttata tcagcaagct gatctggctg gctattcctg tcgcggtttt tgttctcaga
    32041 atgatcacta aacaggacga ccacattttt aacctttact ttcttaagct gaaaatgctc
    32101 ggaaactcag tgtgtaatcg tttttttggc gcacgagcgt tcctctccgg acaatatgaa
    32161 gctgttgaaa ttgatgagtt tgttaatgcc atgaaactga atgagcgaat cactactggt
    32221 aaatatatac cctattcaag ccatgttgat aaaaatattg tcaaaacaaa gaacggtgat
    32281 tatgtagcga catggcaact gatggggatt aactttgagt caatctctgc ggagatgtta
    32341 gaaactattg actcacaggt tgccactctt gttcgttcat tttccggact gcccgtttca
    32401 ttttataacc attcatgcag ggcgagtttt tatgatgcct ttaccacaaa atcaggtaat
    32461 aaatatgctg atataatatc agattgttac tatggttcga tgaagaaaaa taaattcaag
    32521 gggaacactc tttactttac gctgatctac agaccagatg ggcgtgtaga aaaactggaa
    32581 aaacgcaaaa aaagtattaa agaaaagaaa gatgatatta acattcatgt gaagagaatg
    32641 aatgaaatga ttaatacatt ctctggcgct cttgataaat ttacctgtaa acttcttggt
    32701 atgtatgagg agaacggaaa ggtattttct tctcaactgt cattctataa ttatcttctg
    32761 acagggaagt tgcaaaaaat cagagtcact gattctccgg tgtataacgt tcttggtgga
    32821 gtggatgtat tttttaatca tgataccgga cagatatgcc gcattgatgg aaataaattc
    32881 tttcgttcta ttgaaattaa agatttctgt agtgagactg catccggtgt ttttgatgtg
    32941 ctccagtatt ctgatgctga ctatattatt acgcattcat atacatccat gagcaaatca
    33001 gaagcattga gtaccattaa acgtgcggaa aaacagttaa agagtacaga agatgatgcg
    33061 gttactcaat tgcaggaact ggaaaaggca aaaaatgata ttgtgtccgg tgatatatcc
    33121 tttggttact accatttcac gctaatggta atggcggaca gtatcaggga gcttgacgaa
    33181 tctgtaagta aaattacggc agactttact gacctgggca ttattccggc attgtcaacc
    33241 atgtcattgc cagcggcata ttttgcccaa cttccggcgg tttttcattt aaggccgcgt
    33301 ttatctccgg tatcgaatgt aaattttgtt gaactggcat cattccataa tttctaccag
    33361 gggaaacgcg ataaaaactg ctggacagaa gcggttgcta ttctcaaaac accaagcaaa
    33421 caggcgtatt atctgaattt acataactca gtactgttta aagatgaaac aggtgaaaag
    33481 aatcttgcta atactaaagt tataggaacg gcgggttcag gtaagacaat gtttctgtca
    33541 tatcttgcct gttcattaca gaaatacaat aaccccgaaa cttttgctga ttctgcaaaa
    33601 aataagaagt taacgtgtgt ctttcttgat aaggacagag gggctgaatt atgtatccga
    33661 atgcttggtg gggaatatta caccgtaaaa agcggtgagc cgacaggatg gaatcctttt
    33721 gctctggagg caacaaaacg taaccgtatt tttgtcaagc aactgatgga gattctgtgt
    33781 accagaaatg gtgaaagatt atcgacaaga gaaagattgc ttattagcga aagtgttgat
    33841 gctgtgatgg attttcctcc tggcgaaatg cgggaatatg gcattaccag aatgcttgag
    33901 catcttatgc agagagatga tcgggatgag caggagaacg ggattatcct tcgtttgtcc
    33961 caatgggcta atggtcaggc tcatggctgg gtttttgata atgctaaaga cacattcaat
    34021 attcagcatg tcaataattt tggcattgat ggcaccgagt ttcttgatga tccgatggta
    34081 tgtgcaccaa ttactttcta tctgctgtat cgcattacgc agcttctgga cggtcggcgt
    34141 cttgttatct tcctggatga gttctggaaa tggctacagg atgaagcatt cagcgacttt
    34201 gtctataaca agctgaaaac aattcgtaag ctgaacgggc tggttattcc ggcaactcag
    34261 tctccggatg aaatactgaa gaataagatt tcacgggctg tggttgaagt atgcagcacc
    34321 agtatttatc tggctaaccc tgatgccgat tacaatgatt atgtggaagg gcttaagctg
    34381 acaccagaag aatttaatat tgttaaaaat cttgatccaa tgtcgagaca gttcctgatt
    34441 aaaaaaagca gtcttaaaaa gggggatggt aaatcatttt cagcacttgc gacactcgat
    34501 ttatcgggac ttggtggata tctgaaaata ttgtctgcca gtgcagataa tctggaaatt
    34561 tttgaaagta tttatcatga aggaatggag cctgatgact gggttcctga atatctcgaa
    34621 cgggcaatct gacaggtgaa ttt
//
