LOCUS       NZ_MT849281            11194 bp    DNA     circular CON 04-JUL-2023
DEFINITION  Acinetobacter baumannii strain 2014LNAB1 plasmid p2014LNAB1-3,
            complete sequence.
ACCESSION   NZ_MT849281
VERSION     NZ_MT849281.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15538702
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 11194)
  AUTHORS   Li,H. and Wang,Z.
  TITLE     Evolution mechanism of Acinetobacter baumannii in China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11194)
  AUTHORS   Li,H. and Wang,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-AUG-2021) Clinical Laboratory, Peking University
            People's Hospital, No.11 Xizhimen South street, Beijing 100044,
            China
REFERENCE   3  (bases 1 to 11194)
  AUTHORS   Li,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Department of Clinical Laboratory, Peking
            University People's Hospital, No.11 Xizhimen South Street, Beijing
            100044, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method              :: HGAP v. 4
            Genome Representation        :: Partial
            Expected Final Version       :: Yes
            Genome Coverage              :: 126.8585x
            Sequencing Technology        :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Date              :: 07/04/2023 05:07:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 13
            CDSs (total)                 :: 13
            Genes (coding)               :: 13
            CDSs (with protein)          :: 13
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP082890.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..11194
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="2014LNAB1"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /plasmid="p2014LNAB1-3"
                     /geo_loc_name="China: Liaoning, Shenyang"
                     /collection_date="2014-05-05"
     gene            283..1218
                     /gene="repM"
                     /locus_tag="H1I72_RS00005"
                     /old_locus_tag="LF597_RS00005"
     CDS             283..1218
                     /gene="repM"
                     /locus_tag="H1I72_RS00005"
                     /old_locus_tag="LF597_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005065049.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_001292329.1"
                     /translation="MSELIVKDNALIQASYTLDTVEQRLILLAIAEARETGHGITENSL
                     LEVHASSYINTFNVEKHTAYTVLREASKSLFDRYVTYHDINPKTGKDRSFHCRWVDKIG
                     YESQSGIIFLRFTQDIVPLITRLEENFTKYELQQVSRLSSSYAIRLYELLIQWRSAGKT
                     PLFDLSIFRQQLGVKPHQYKTMSNFKTYVLDFALKQVNELTDITAKYEQHKKGRSISGF
                     SFTFKQKKMSNLPIKNKRDPDTIDIFSKMTDAQRHLFSHKLSELPEMGKYSHGTESYPQ
                     FAVRIAEMLQNPEKFKELYPYLQKVGFKAA"
                     /name="repM"
     gene            1296..1814
                     /locus_tag="H1I72_RS00010"
                     /old_locus_tag="LF597_RS00010"
     CDS             1296..1814
                     /locus_tag="H1I72_RS00010"
                     /old_locus_tag="LF597_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_000839337.1"
                     /translation="MKSLTVLELSKLYNINRQTIYNNIKKGILSKNSDNKIDLAEAIRV
                     FGEPVQKQSVKETVKVDSPTSAEVLLLRQQIDLLKNQLDDAKNRESFYQNQIETMQRLL
                     EAPKTNTTQSDDPGSTQAESTVEEKEDVIAMPPKESEVIENKRIPVPEHIEPEPEKRGF
                     WSRFFKPYG"
                     /name="plasmid replication DNA-binding protein"
     gene            2024..2323
                     /locus_tag="H1I72_RS00015"
                     /old_locus_tag="LF597_RS00015"
     CDS             2024..2323
                     /locus_tag="H1I72_RS00015"
                     /old_locus_tag="LF597_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000358348.1"
                     /translation="MDKKIEEKTKDINEKIQKLDLAIQELIETTDNFFINDKYYGIECA
                     FILDHALNIKMHFFNKYPAFAPPHLRGVENYDRIIHIRENNPEDKLEQISPLKD"
                     /name="hypothetical protein"
     gene            2889..3245
                     /locus_tag="H1I72_RS00020"
                     /old_locus_tag="LF597_RS00020"
     CDS             2889..3245
                     /locus_tag="H1I72_RS00020"
                     /old_locus_tag="LF597_RS00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005194067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269904.1"
                     /translation="MWTVITTDLFNEWLEQQDEATQEKVLAALVVLQQQGPSLGRPLVD
                     TVYDSKFTNMKELRVQHRGKPLRAFFAFDPLRQAIVLCIGDKSNKKRFYTEMLAIADEQ
                     YALHLSTLGDQSNG"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            3238..3540
                     /locus_tag="H1I72_RS00025"
                     /old_locus_tag="LF597_RS00025"
     CDS             3238..3540
                     /locus_tag="H1I72_RS00025"
                     /old_locus_tag="LF597_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001129974.1"
                     /translation="MAKSLQELLASRSPESQARIQKMADELLLESQLHLIREELEISQK
                     ELAATLGIKQPSLSAIENRGHDLKISTMKKYVEAMGGKLRIDVELPTGKHIGFNV"
                     /name="helix-turn-helix domain-containing protein"
     gene            3533..3742
                     /locus_tag="H1I72_RS00030"
                     /old_locus_tag="LF597_RS00030"
     CDS             3533..3742
                     /locus_tag="H1I72_RS00030"
                     /old_locus_tag="LF597_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000069474.1"
                     /translation="MSNNKPLKNSTKLLVNLDKFIFLVNAADSLEEIEIIRDLCCEYFS
                     HCKRPSYYIDIFDNAYWIKYYEIA"
                     /name="hypothetical protein"
     gene            complement(4068..4529)
                     /locus_tag="H1I72_RS00035"
                     /old_locus_tag="LF597_RS00035"
     CDS             complement(4068..4529)
                     /locus_tag="H1I72_RS00035"
                     /old_locus_tag="LF597_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004781077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DIP1984 family protein"
                     /protein_id="WP_000761346.1"
                     /translation="MKLAEALLLRSDQQKKIISLKQRINANVLVQDGDQPSEDPNELLK
                     QVFSLIQEFQKLSYAIHETNALTKLNDGRSLLALLTLRDEFVEQHKTLTAAISNTSRES
                     DRYSTREIKWHKVIPVSSLQKQADDISLKLRDLNVLIQSTNWKIDLIEA"
                     /name="DIP1984 family protein"
     gene            complement(4834..7245)
                     /gene="znuD2"
                     /locus_tag="H1I72_RS00040"
                     /old_locus_tag="LF597_RS00040"
     CDS             complement(4834..7245)
                     /gene="znuD2"
                     /locus_tag="H1I72_RS00040"
                     /old_locus_tag="LF597_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor ZnuD2"
                     /protein_id="WP_225370903.1"
                     /translation="MLNKSKLFLALITLGASKILLAAEGPVTTLNTIVLTAQSDELGSE
                     LLGKSLNVSNQFIDTSKLKQRSTTLGDALGTELGIHSNQYGGGASTPIIRGQEGKRIKV
                     LQNNADVLDMSNMSPDHAVTVEPSLAKSIEIIRGASTLLYSSNSAAGVVNVIDYKIPTQ
                     MPQDGLEGNTTLRFNTGSNEKLTTAGVTVGLSPHVALRAEGLYRNAGNYKTPHYQSSSY
                     NSLEDLENQNSIYKNLKYLPESWAESRVGTLGLSWIDDNTYLGVSYTHRHDEYGLPAHS
                     HLYEGCGASAIGIDSRISGLKNYLLYYPQLMDEQDINYINPRPDCHQHNHIHETNFSHN
                     APYIDLNTRRYDVRGEFTQPFTGIDKIRTSLSYIDYFHNELEGDKITNFFKNTGKVGRI
                     ELSHQPLGELTGILGLQYLEQDNSALSPVHSQEGHTTYLDNQQLLNRNVTKNFSVFGLE
                     KYNWNDFTFELGARIEKQKVSMDYDIEKIKDSMKPWPNKYNSPYVEKNNKIRAQNLKSI
                     LEAVQPNKETAFSYAGTVHWRFAPNYILSLTGTHQERLPNAQEMYTHGMHLATNSFEIG
                     NRFLRKEKSNNLEISLAYKDDLLDYQISTYYYDFDNYIYLQTLNEVLGTTKVRDQHTLR
                     INHYSQSAANFYGLEGNIGYQFNSVYHGSLFGDYVKGRLTNLPDAVIAYDIWNREPTLA
                     PQKDRYTPRLPPARLGTRLKADFDESLKGEIEYYRVFKQDNISKFEQVTSGFNMLNMTL
                     AYKNKLSHTEYDLFFKANNLLDQKVYAHETFLPYIPQIGRNFSLGLNLNF"
                     /name="znuD2"
     gene            complement(7373..7687)
                     /locus_tag="H1I72_RS00045"
                     /old_locus_tag="LF597_RS00045"
     CDS             complement(7373..7687)
                     /locus_tag="H1I72_RS00045"
                     /old_locus_tag="LF597_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006582675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="WP_001983304.1"
                     /translation="MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEI
                     TDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQGKGYQTRMNEILRDAMLKELKNHQ
                     "
                     /name="BrnA antitoxin family protein"
     gene            complement(7674..7961)
                     /locus_tag="H1I72_RS00050"
                     /old_locus_tag="LF597_RS00050"
     CDS             complement(7674..7961)
                     /locus_tag="H1I72_RS00050"
                     /old_locus_tag="LF597_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019383542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="WP_000438827.1"
                     /translation="MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRYTNG
                     EERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIISARQVTKAERNKYEHG"
                     /name="BrnT family toxin"
     gene            complement(8229..8528)
                     /locus_tag="H1I72_RS00055"
                     /old_locus_tag="LF597_RS00055"
     CDS             complement(8229..8528)
                     /locus_tag="H1I72_RS00055"
                     /old_locus_tag="LF597_RS00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000358348.1"
                     /translation="MDKKIEEKTKDINEKIQKLDLAIQELIETTDNFFINDKYYGIECA
                     FILDHALNIKMHFFNKYPAFAPPHLRGVENYDRIIHIRENNPEDKLEQISPLKD"
                     /name="hypothetical protein"
     gene            complement(8645..9406)
                     /locus_tag="H1I72_RS00060"
                     /old_locus_tag="LF597_RS00060"
     CDS             complement(8645..9406)
                     /locus_tag="H1I72_RS00060"
                     /old_locus_tag="LF597_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017393773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000425105.1"
                     /translation="MEMEKAKKRGRPAQLLQIAELHAFVEFLEQQEQLSDLQSQVLKAL
                     NSVDCNFEGLTQTDQVLVKEALKPYREHLKLKLLFEELNNLPLKTEYEQKFLDLYELFQ
                     KNALDQMELNILKTLATRYLNFKAQKLEYSDLELYLSQLQKKDAGKKRKAENQRKFELG
                     GAVLVAFKKLNIDISNDTPQQITNRIVNTTKFHNEVRKSLIFKDVKTYENEYFKANKLF
                     IQVLEGLHTWQKGGELLSVIEIKKALEKGEE"
                     /name="hypothetical protein"
     gene            9711..10880
                     /locus_tag="H1I72_RS00065"
                     /old_locus_tag="LF597_RS00065"
     CDS             9711..10880
                     /locus_tag="H1I72_RS00065"
                     /old_locus_tag="LF597_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_002134206.1"
                     /translation="MASYHFSVKSKNKGYATGHYLYISRLMQYEGIRKTSNETIEHIEP
                     GRCMPAFVKDPIDFWQAADTYERANAKAYMEYEIALPNEFTSEQRKTLIETFLDKHIVP
                     QQYPHSYAIHNVKSRISGEDQPHCHLMFSLKADDGIERSAEQYFKRYNPQDPAKGGAKK
                     IQLQDGHEDYSTFLIYIRKQWENHLNDALAQHCPTVTYTLDGQDITIKNQVSADSYEKY
                     NEIHSTLYLPEPKLGVGQQNATAEYLAQIQKIREHNQQERELEERQKQLDQQHEYFYSA
                     ENNPFSSLEVMYYLNYLIKNATNKDKLKNDLNEIIKNQGPILKQEAWSIYEMNEKLEDS
                     RRNSTPCFEFEVHSLPEYVLPIQNTPPKRTQSEPVQPKADDYDYGGPGF"
                     /name="MobA/MobL family protein"
     Typing          284..1218
                     /name="rep_cluster_1226"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9790..10877
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 agggcaattt ttcattcatt gggcttttaa ttatttttaa tcttttaaat gcttttaaat
       61 aagctgtaaa cctttattta taatagtttc atagttaata aaactaggtt tatcgaccca
      121 taaaactagg tttatcgacc cataaaacta ggtttatcga cccataaaac taggtttatc
      181 gaccttaaag ctaggtttat cgacccataa ttaagttaat ttacaactca attgaaatag
      241 tctattgtac aacctagttt aattataaat ttattattag aaatgagtga attaatcgta
      301 aaggataatg ctctaattca agcaagttat accttagata cagttgaaca aagactgatc
      361 ctattagcca ttgctgaagc tcgagaaact ggacatggga taactgaaaa tagtctttta
      421 gaagtacatg caagtagtta tataaatact tttaatgtcg agaaacatac cgcttatacc
      481 gtactcagag aggcatctaa aagcttattt gatcgctatg tcacatacca tgacattaat
      541 cctaagacag gtaaggatcg tagctttcat tgtcgttggg tcgacaaaat tgggtatgaa
      601 tctcaatcag gaattatttt cctacgattc acccaagata tcgttccact cataactcga
      661 cttgaagaaa atttcactaa atatgaattg cagcaggttt ctaggttaag tagctcatat
      721 gctattcggc tatacgagct attaattcaa tggagatctg ccggaaaaac gccacttttt
      781 gatctatcta tctttagaca acaacttggt gtcaaacctc atcaatacaa aacaatgagt
      841 aactttaaaa catatgtttt agattttgct cttaagcagg taaatgagtt aaccgatata
      901 acagctaaat atgagcaaca taaaaaaggg cgttctattt caggtttttc attcactttc
      961 aaacagaaaa aaatgagtaa tctgccaata aaaaataagc gtgacccaga cactatagat
     1021 attttctcaa aaatgacaga tgctcaacgc catctgtttt cccacaaact gtcagaactt
     1081 cctgaaatgg gaaagtattc tcatggtaca gaaagctatc cgcaattcgc tgtacgcatt
     1141 gcagaaatgc ttcaaaaccc agaaaagttt aaagaactct atccttatct ccaaaaagta
     1201 ggcttcaaag ctgcatagaa gatagacttg ctgatttgtc tattagacag tctaatagac
     1261 actaattttt tacaagatta ggcagagatt tacacatgaa aagccttaca gttcttgagc
     1321 tttctaagct ttacaatatt aatcgacaaa ccatttacaa caatataaag aaaggtattt
     1381 taagtaaaaa ttctgacaat aagattgatc ttgcagaagc gatccgggta tttggtgagc
     1441 cagtacaaaa acagagtgta aaagaaactg taaaagtaga cagtccaact tcggcagaag
     1501 ttttactcct tagacagcag atagacctac taaaaaatca gctagatgat gcaaaaaata
     1561 gagaaagctt ctatcaaaat caaattgaaa ctatgcaacg cctattggaa gctccaaaaa
     1621 ccaatacaac acaatctgat gatcctggat caacacaggc agaatccaca gtagaagaaa
     1681 aagaggacgt catagctatg cctcctaagg agtcagaggt tatcgagaat aagcgtattc
     1741 cagtccctga acatattgag ccagaaccag aaaaaagggg cttctggagc cgttttttca
     1801 agccctatgg atgataggac tatttaatca gactaatcaa aaccgtggaa caatgatcaa
     1861 taattgatcg tgaaacataa aaaatcacta aaacagcctg agcgtgactg cttaggctgt
     1921 ttttacatcc ataagacatt gttttaaaat gctttttaca aagaatttcg tataaggtgt
     1981 attatgttaa ttttagggaa acttaattct ataggtgata ccaatggaca aaaagataga
     2041 agagaaaact aaagatatta atgaaaaaat tcaaaaattg gatttagcta ttcaagaact
     2101 aatagaaact acagacaatt tttttattaa tgataagtac tatggaattg aatgtgcttt
     2161 tattttagac catgcactaa atattaaaat gcactttttc aacaagtatc cagcatttgc
     2221 accacctcac ttacgaggag tagaaaatta tgatcgaatt atacatatta gagaaaataa
     2281 tcctgaagat aagctagaac aaatttctcc tcttaaagac taaattttct aatcttgtac
     2341 ttagagtccc ctactattta acataatgga tattatgcga aatggatctt taagattact
     2401 ttaagatcag tagcttacat tgagtcatac cctctggaac gacctcgttc aaccgactta
     2461 gaaacaagtc ggttttttta tgctcaattt tgatacttct tgccaataaa attgtttaaa
     2521 aaataatcaa aaatagcaat tccatagagt ttataagctt ttttacccaa aagaatccac
     2581 tatttctgtg gataaccact gggataaatt ttgattattt tttgtacgtt ttggcttaca
     2641 gcgtttcacg aaattgtctg tatctatccc ccgatgaagc tcttatgatc gatctatatg
     2701 gacaggatgt tcaatgactt aaaacaacaa taataatcag tcaggcacca tgaccatcag
     2761 gtagtcagcc ctacctatgc gctccatacc gaaaaatccc gacatgacgt cgggattttt
     2821 tattgccatt tgcaaagtca ttcaatcaga tttaatatat agactgtaat ctatattgtg
     2881 attgtaatat gtggacagtc attacaacgg atctgtttaa tgaatggctt gaacagcaag
     2941 atgaagcaac acaagagaaa gtcttagctg cattggttgt tctacaacag caagggccta
     3001 gtttaggtcg tcctttagta gataccgtct acgattctaa atttaccaat atgaaggaac
     3061 tacgtgttca gcatcgtggt aaaccgttaa gggcattttt tgcattcgat cccctaagac
     3121 aagcgattgt gctgtgtatt ggtgataaga gtaataaaaa gcgtttttat acagagatgc
     3181 tagcaattgc agatgagcaa tacgcacttc atctctcaac tttaggagat caatctaatg
     3241 gctaagagct tacaagaatt attggctagt cgctctccag agagtcaagc tcgtattcaa
     3301 aaaatggctg atgaattact tttagaaagt cagcttcacc ttatccgaga agagttagaa
     3361 atttcccaga aagaactagc tgcaaccctt ggaattaaac agccgtcatt atcagcaatc
     3421 gaaaatcgtg gtcatgatct taaaatttca acgatgaaaa agtatgttga agcaatgggt
     3481 ggaaaacttc gtattgatgt agagcttcca acaggaaaac acatagggtt caatgtctaa
     3541 taataaacct ttgaaaaata gtactaaatt acttgttaac ttagacaagt ttatattttt
     3601 agtcaatgct gccgatagcc tagaagaaat tgaaattatt agagatttat gctgtgaata
     3661 tttttcacat tgtaagaggc caagctatta cattgatatt tttgacaatg cttattggat
     3721 aaaatattac gaaatagctt aatccttcta gattcgcata agagatttta tgttaaatgc
     3781 cgaaatgaat taaaaataga aatgtagttg agctgatgct tgctcatttc tttattttta
     3841 gtaattgagg tgaacatact gtcagtacat ggtagttata agtaacgtgt aactttgttt
     3901 gcacaaagat ttgagttatg ccaagtgatg gattgatttg tacttaaaat tttaagctta
     3961 tccacttgct ttgcaagcca ctacacttta tttacaatcc tatgttgtgg aagtaaggga
     4021 tcttgtactc gcccagtatg ttcaacttga ttatatctaa aggactatta ggcttcaatc
     4081 aaatcaattt tccaattagt cgactgaatt aacacgttta aatcacgtaa tttaagacta
     4141 atatcatcag cttgtttttg taatgatgaa actggaataa ctttatgcca ctttatttcc
     4201 cgcgtactat aacgatcaga ttcacgagat gtattactta ttgctgcagt tagggttttg
     4261 tgctgttcta caaattcatc acgcaaagtc aataaagcaa gtagagaacg gccatcattt
     4321 aattttgtta aagcattagt ttcatgaatt gcataactta atttttgaaa ttcttgaatt
     4381 aaagaaaata cttgttttag tagttcattt ggatcttcag atggttgatc accatcttgt
     4441 accaatacat ttgcattgat acgttgtttt agtgaaataa tttttttttg ttgatcactt
     4501 cgaagtaaga gagcttctgc taatttcatt tttcacctat taaccaatta gaattaagtt
     4561 ttaaacagct tatatcctca ttctttaaag atcaaaaaaa ttgcttttta tctagctaaa
     4621 aggtgtctac aaaatcggtg gctattcagt gctgaaaagg ctgccgacac ataaagtgac
     4681 ccagattgaa gagttactgc cacactgctg gaaacctaaa tcgaattaaa aaataggtat
     4741 gggattcagc ggacgcttac cttaattatt aatctaatca ttttataaga aaaatcttct
     4801 aagaaatttt cttagaagat tacagtatct tatctagaaa ttaagattta agcctaaact
     4861 aaaatttctt ccaatttggg gaatatatgg caaaaatgtt tcatgggcat agactttctg
     4921 atcaagtaaa ttattcgctt taaagaataa atcatattct gtgtgagata gcttattttt
     4981 atatgctaaa gtcatattaa gcatattaaa acctgatgta acctgctcaa atttagaaat
     5041 attatcttgt ttaaagactc gataatattc tatttcacct ttaagcgatt catcaaaatc
     5101 agcttttagt cgtgtaccca aacgagcagg aggtaatcta ggagtgtaac gatccttttg
     5161 gggagctaaa gtcggttctc tattccagat atcgtatgca attacagcat caggtaaatt
     5221 tgttaaacgg cctttcacat aatctccaaa aagagagccg tgataaacag aattaaattg
     5281 ataccctatg ttgccctcta atccataaaa attagcagca gactggctat aatgattaat
     5341 acgtagtgta tgctgatctc taacttttgt agttcctaaa acttcattga gtgtctgtaa
     5401 atatatatag ttatcaaaat cataatagta agtactgatt tgataatcaa gtaaatcatc
     5461 cttataggcc agactgattt ctaaattatt ggatttctct tttcttagaa agcggttacc
     5521 tatttcaaaa gaattagtag cgagatgcat accatgagta tacatttctt gtgcattagg
     5581 taatctttct tgatgtgtac ctgttaatga taagatataa tttggagcaa atctccagtg
     5641 gactgtacct gcataagaaa aagctgtttc tttgttaggt tgaacagctt ctaaaataga
     5701 ttttaaattt tgagccctga ttttattatt tttttctaca taaggactgt tatatttatt
     5761 aggccaaggt ttcattgaat ctttaatttt ttctatatca taatccatac taactttctg
     5821 cttttctata cgagcaccta gttcgaaagt aaagtcgttc cagttatatt tttctaggcc
     5881 aaatacacta aagtttttag tgacatttcg atttaatagc tgctgattat ctagataggt
     5941 ggtatggcct tcttgagaat ggactggtga taaagcacta ttatcctgtt ccaaatattg
     6001 tagccccaag ataccggtta attcccctaa tggctgatgt gataactcta tgcggcctac
     6061 ttttcctgta tttttaaaaa agttagtaat cttatctccc tcgagttcat tgtgaaaata
     6121 atctatataa ctcaatgagg tacgaatttt gtcaataccg gtaaatggtt gagtgaattc
     6181 tccacgcaca tcataacgtc gagtatttaa atcaatataa ggagcattat gagagaaatt
     6241 agtttcatga atatgattat gctgatgaca atcaggacgt ggatttatgt aattaatatc
     6301 ttgctcatcc atcaattgag gataatataa aagataattt tttaatccac taattcgtga
     6361 atcgataccg attgcagagg caccacaacc ttcatataaa tggctatggg ctggtaaacc
     6421 atattcatca tgacgatgtg tataagaaac tcctaaataa gtattatcgt ctatccagga
     6481 taatccaagc gtacctactc tcgactctgc ccagctttct ggtaaatatt ttaaattttt
     6541 ataaatactg ttttggtttt caagatcttc taaagaatta taagagctag actggtaatg
     6601 aggagtttta tagttaccag cattacgata taacccttct gcccgtaaag ctacatgtgg
     6661 gcttaagcca actgttacac ctgctgtggt caacttctca ttactgccag tattaaaacg
     6721 taatgtagta ttaccctcta atccgtcttg aggcatttgg gttggaattt tatagtcaat
     6781 gacattgact acccctgccg cactatttga actatacaaa agggtacttg caccacgtat
     6841 aatttcaata gacttagcta aacttggttc aactgtgaca gcgtgatctg gagacatatt
     6901 agacatatcc aacacgtcag cattattctg taaaacttta atacgttttc cttcctgccc
     6961 acgaataata ggagtagatg ctccacctcc atattgatta gaatgaattc ctaattccgt
     7021 acccaaggca tcccctagag ttgtcgaacg ctgtttaagt ttactagtat caataaactg
     7081 attactaaca tttagacttt tgcctaacag ctcagaccct aactcatcag attgtgcagt
     7141 taatactatt gtatttaagg tagtaacagg cccttcagct gccaataaaa ttttcgaggc
     7201 ccctaaagta attaaagcta aaaatagttt acttttattt agcataaaac aaccaaattt
     7261 aatgttatat tataatataa cacttaaaaa tttataaaat ctactattta aatttttgaa
     7321 tggtaatccc ccctaaaaat gaagtcaaaa atgggagcct aagctcccat tcttattgat
     7381 gattttttaa ttcttttagc atagcatctc gtaaaatttc attcatacgt gtttgataac
     7441 ctttgccttg tgctttgaac caagcaagta catcagcatc taaccgaatt gaagtttgtt
     7501 gctttactgg gcggtaaaat tgattttggc gtacagcatt gctccagtct gtaatttcag
     7561 gaatatctga tagatctagc tgatcatcag gaaccgtgcc tttagcaagc aagcgttgaa
     7621 tttcagcatc ttgcttctca ccaaatttct cattcagctc tttgtgtgag tatctaacca
     7681 tgctcatatt tgtttcgctc cgctttagtg acttgccttg cactaatgat tcggatgatt
     7741 tcacagtcat cttcatcaaa aatggtgtga gccaccaata acattagtac gcctttaact
     7801 cgtccaatgg tttgccaacg ttcttcacca ttagtatatc tgtcttggat tgagatccgt
     7861 aatggatctt caaaaacaag gcttgcagtt tcgaaagaga tatcatgctt tttctgattc
     7921 tttcgattct tagcctcatc ccattcaaaa tactgttcca taaaaaatat tcaaatttgt
     7981 atatacaata atgtatcacg aaattgtatc actcaagttg agaagcgtaa tttttagtca
     8041 gatttattgg caaaaactat caaaatcgat cataaaaaag ccgacttgtt tcaaagtcgg
     8101 ctttttgggc atttttggat ttttatattt ttattaagta gttgatattt aaattaatat
     8161 acaagtgtac ttcgtataat atccattatg ttaaatagta ggggactcta agtacaagat
     8221 tagaaaattt agtctttaag aggagaaatt tgttctagct tatcttcagg attattttct
     8281 ctaatatgta taattcgatc ataattttct actcctcgta agtgaggtgg tgcaaatgct
     8341 ggatacttgt tgaaaaagtg cattttaata tttagtgcat ggtctaaaat aaaagcacat
     8401 tcaattccat agtacttatc attaataaaa aaattgtctg tagtttctat tagttcttga
     8461 atagctaaat ccaatttttg aattttttca ttaatatctt tagttttctc ttctatcttt
     8521 ttgtccattg gtatcaccta tagaattaag tttccctaaa attaacataa tacaccttat
     8581 gcgaaattcc aatgtaagcc caaaatagaa atgtccaact tctctaaaat ccctgctaaa
     8641 taaactactc ttcgcctttt tctaaggcct ttttaatttc aattactgac aataattctc
     8701 cgcccttttg ccaggtatgt aatccttcta acacctgaat aaaaagttta tttgctttaa
     8761 aatattcatt ttcatatgtc ttaacatctt taaaaattaa agatttacgt acttcattat
     8821 gaaactttgt cgtattcaca atccgattgg taatctgttg aggagtatca ttgctaatat
     8881 caatattgag tttcttaaat gcgacaagaa cagcaccacc taattcaaat ttacgttgat
     8941 tttcagcttt gcgttttttc ccagcatcct tcttctgtag ctgactcaaa tacaattcta
     9001 aatcactgta ttcaagcttt tgcgctttaa aattcagata ccgtgtcgcc aaggttttta
     9061 aaatatttag ttccatctga tctagtgcat tcttttgaaa aagttcatac agatctaaaa
     9121 acttctgttc atactcggtt ttaagaggca gattattcaa ctcttcaaac agcaatttca
     9181 acttcagatg ttcacgataa ggttttaaag cctctttgac cagaacctga tctgtctgag
     9241 ttagcccctc aaaattacaa tcaacactat ttaaagcctt taacacttga gattgaagat
     9301 cagaaagctg ttcttgctgt tctaaaaact ctacaaatgc atgtaactca gcaatctgta
     9361 acaactgagc aggtcgacca cgcttttttg ctttttccat ttccatcatc tgccgccaaa
     9421 ttttcagaac tgcaacctct ttaaatatgg ttttaccata tttaaagagg gcagtctgaa
     9481 aataattatt taatataaaa ataaaaattc ttttcaagaa attttatttt tatattaaat
     9541 aattcgcact tgacagtttc tcctcatcgg agaaactagt acgcaatggg gcgcttcccc
     9601 cttgaccccc ttcaaccgga tttttcagcc atacaggcat ttcaaatccg ggcggttttc
     9661 attccgtttc actgcataaa aaccgaaccc acaacccagc agaggtgaac atggccagct
     9721 accacttcag cgtcaaaagc aaaaataagg gctatgcgac cggccattat ctctacattt
     9781 cccggctgat gcagtatgaa ggcatccgca aaaccagcaa tgagaccata gaacatattg
     9841 aacctggtcg atgtatgcct gcctttgtaa aagatcccat tgatttttgg caggcagcag
     9901 atacgtatga acgagccaat gccaaggcct acatggagta tgaaattgcc ctaccgaatg
     9961 agttcacgtc agaacagcgt aaaacgctca tagagacgtt tttagacaaa catatagttc
    10021 cacagcaata tccgcactca tacgccatac acaacgtaaa atcacgtatc agtggcgaag
    10081 atcagcctca ttgtcatctg atgttctcgc taaaagcgga tgacggcatt gaacgcagcg
    10141 cagaacagta cttcaaacgc tataaccctc aagatccagc caaaggcggt gccaaaaaaa
    10201 tccaacttca agatggccat gaagactatt ccactttttt gatctatatc cgaaaacaat
    10261 gggaaaatca tttgaatgat gcccttgcac agcactgccc gaccgtcacc tacacactgg
    10321 atggccaaga catcaccatc aaaaatcagg tttcagcaga cagctatgaa aaatataacg
    10381 agatccacag cacgctatac cttccagagc caaaactagg cgttggacaa caaaatgcga
    10441 cagcggaata tctcgcccaa atccaaaaaa tcagagaaca caaccagcaa gaacgagaac
    10501 tcgaagaacg ccaaaagcaa ttagatcaac aacatgaata tttttatagt gctgaaaaca
    10561 acccattttc atcattggaa gtcatgtatt acctgaatta cttaatcaag aatgcaacaa
    10621 ataaggacaa actaaaaaat gatttgaatg aaattatcaa aaaccaaggc cctatactta
    10681 aacaagaagc ttggtccatc tacgaaatga atgaaaaact agaagactca agacgtaaca
    10741 gtaccccatg ttttgagttc gaggtgcatt cacttcctga atacgtatta ccgatacaaa
    10801 atacgcctcc caaacgcact caatcagaac cagtacaacc taaagctgat gattatgatt
    10861 acggtggccc tggtttttaa gctcagttgg ttttatccaa agtttacaga gcgagtgtct
    10921 acgagcgaac agacacaatt aaaatttttg ccatgctttt tccctgatta caaactcccc
    10981 tttgctgctg agactgagat acagagcatc ccggagggtg cgaacagatt taatttgcat
    11041 ctaggtcgag cgaagcgagt ataaaaaact tatgagcgaa gcgaattccg agttgctttt
    11101 gcttttttga agttatcacg agattaaccc aaaaattgcc ccttcgaact gagcgtaagc
    11161 gaagttcaat agagtttgag cgtagcgaaa acat
//
