LOCUS       NZ_MT090962            11970 bp    DNA     circular CON 10-JAN-2024
DEFINITION  Klebsiella pneumoniae strain KP18-2079 plasmid pKP18-2079_11kb,
            complete sequence.
ACCESSION   NZ_MT090962
VERSION     NZ_MT090962.1
DBLINK      BioProject: PRJNA224116
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 11970)
  AUTHORS   Qin,S. and Li,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2020) Zhengzhou University, Institute of Drug
            Discovery & Development, 100 Science Avenue, Zhengzhou City,
            Zhengzhou, Henan 450001, China
COMMENT     ##Assembly-Data-START##
            Assembly Method              :: CLC Genomics Workbench v. 10.0
            Sequencing Technology        :: Illumina; PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Date              :: 01/10/2024 00:30:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.6
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 14
            CDSs (total)                 :: 14
            Genes (coding)               :: 14
            CDSs (with protein)          :: 14
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MT090962.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..11970
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP18-2079"
                     /isolation_source="blood from male"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pKP18-2079_11kb"
                     /geo_loc_name="China"
                     /collection_date="22-Nov-2018"
     gene            complement(1406..1555)
                     /locus_tag="H5H37_RS00005"
     CDS             complement(1406..1555)
                     /locus_tag="H5H37_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(1640..1897)
                     /locus_tag="H5H37_RS00010"
     CDS             complement(1640..1897)
                     /locus_tag="H5H37_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            complement(1907..3592)
                     /locus_tag="H5H37_RS00015"
     CDS             complement(1907..3592)
                     /locus_tag="H5H37_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            complement(3697..5184)
                     /gene="ltrA"
                     /locus_tag="H5H37_RS00020"
     CDS             complement(3697..5184)
                     /gene="ltrA"
                     /locus_tag="H5H37_RS00020"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_004178082.1"
                     /translation="MMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
                     /name="ltrA"
     gene            5829..6074
                     /locus_tag="H5H37_RS00025"
     CDS             5829..6074
                     /locus_tag="H5H37_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            6348..6719
                     /gene="tolA"
                     /locus_tag="H5H37_RS00030"
     CDS             6348..6719
                     /gene="tolA"
                     /locus_tag="H5H37_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            6716..7081
                     /locus_tag="H5H37_RS00075"
     CDS             6716..7081
                     /locus_tag="H5H37_RS00075"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            7256..7534
                     /locus_tag="H5H37_RS00040"
     CDS             7256..7534
                     /locus_tag="H5H37_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            7522..7836
                     /locus_tag="H5H37_RS00045"
     CDS             7522..7836
                     /locus_tag="H5H37_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            8000..8428
                     /locus_tag="H5H37_RS00050"
     CDS             8000..8428
                     /locus_tag="H5H37_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            8454..8633
                     /locus_tag="H5H37_RS00055"
     CDS             8454..8633
                     /locus_tag="H5H37_RS00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(8660..9190)
                     /locus_tag="H5H37_RS00060"
     CDS             complement(8660..9190)
                     /locus_tag="H5H37_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(9197..9928)
                     /gene="mobC"
                     /locus_tag="H5H37_RS00065"
     CDS             complement(9197..9928)
                     /gene="mobC"
                     /locus_tag="H5H37_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            complement(9928..11892)
                     /locus_tag="H5H37_RS00070"
     CDS             complement(9928..11892)
                     /locus_tag="H5H37_RS00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_071177727.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     BGC             1..8592
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          725..1303
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(9201..9928)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.35e-140"
ORIGIN
        1 ggcatggcgg cggcggtcac gtccgtggtg attgcgttca gctttcaccg cggaggccag
       61 cctctttccg ccccatgcgg aaaaggcgca gccccggagg aacaacgagc acgccccagc
      121 gtgtgagagg aaaaggcggc accccagtgc ggtcttttcc ggtgttccgg cccccgtcag
      181 agttcgccat agcgagcggc tgaccacccg caaaatcagg agcagctttg ctgcttcgtc
      241 aggtgcgtcc agcaccgtgg atttttgtgg gtggtcaggc gtgagcctga cgggggccgg
      301 gtgaatttct ggcgtggccg gcgtccagcc ggacagagcc agaaagaggg gaaaagaccg
      361 tgcgtcggtg gcgtccagcc agcgtaagca aggtcttttc ccctgaagtc agccacgccc
      421 cagcggggat gacttgcatt tctccgcaag gagaaaaaag caacagagat aggttaacgt
      481 aaaatgttca gcgaaaaacc gacatggttc acctatcctg ataattgatc gtcagggaat
      541 agaaagactt aatcagggga caatatccca catcagcgcg tccggtgacc gtcttgcagg
      601 tgccggggaa attgcgcctc ctcgctcact cggtcgctac gctccgggcg tgagactgcg
      661 gcgggcgctg cggacacata caaagttacc cacagattcc gtggataagc aggggactaa
      721 catgtgaggc aaaacggcag ggccgcgccg gtggcgtttt tccataggct ccgccctcct
      781 gccagagttc acataaacag acgctttttc ggtgcatctg tgggagccgt gaggctcaac
      841 catgaatctg acagtacggg cgaaacccga caggacttaa agatccccac cgtttccggt
      901 aggtcgctcc ctcttgcgct ctcctgttcc gaccctgccg tttaccggat acctgtccgc
      961 cgttctccct tgcgggaagt gtggcgcttt ctcatagctc acacactggt atctcggctc
     1021 ggtgtaggtc gttcgctcca agctgggctg taagcaagaa ctccccgttc agcccgactg
     1081 ctgcgcctta tccggtaact gttcacttga gtccaacccg ggaaagcacg caaaacgcca
     1141 ctggcagcag ccattggtaa ctgggagttc gcagaggatt tgtttagcta aacacgcggt
     1201 tgctcttgaa gtgtgcgcca aagtccggct acactggaag gacagatttg gttgctgtgc
     1261 tctgcgaaag ccagttacca cggttaagca gttccccaac tgacttaacc ttcgatcaaa
     1321 ccacctcccc aggtggtttt ttcgtttaca gggcaaaaga ttacgcgcag aaaaaaagga
     1381 tctcaagaag atcctttgat cttttctact gaaccgcgat ccccgtcagt tcagaggagg
     1441 acgatggtgc caccgttccg ccctgaacat cccggatata atttgcctga catgcggcca
     1501 gaagaaagcc agcaacaatc aatataaaaa gaaaaatagt ctttaccttt ttcatatact
     1561 ttccctgtat ttaaagactc cggcattcat ccctgaacac cggaagtcag tatttcaaat
     1621 catccttgat aattttttgt taccagttac cgtcccgata atcaaaagct atataacaat
     1681 tatccacatc aggttttatt tgatttttaa aaaatggctg tagtaaagga acccattctt
     1741 tcttcaaatc aaactcacca ttattaatat tatcctttaa aggcattccc aagctttcaa
     1801 tgacagaacc atcgtcacca aagtctttag aatactcttc ccctttaaac tcttcagttt
     1861 tcttatcaaa ccatgtcaaa cgtaatttaa gccccatatt tacctctcaa agatattttt
     1921 taatgttccg ttttggatct ggccctttaa cctgcttacc cgttttggga tcaaatgcgc
     1981 ctaggtgttc gccatcactg gcacgatacc cttcaagctc accgtgctgg gaatcccatt
     2041 cataaatttt acgtttttta tcgccatacc atcgggcccg cttaccacca ccaccttgtt
     2101 taggtgtttt aggatcacct cgctttaact ctccaagtcc ctttatgtct tctgttttag
     2161 gtactggatg ataatcatgg ccgtagtctt tagtcccctt gcgaggcttg ttcttttcct
     2221 catttaactt attttctgca tccttcgctt ttttctcctt ttgtttccgg ctctccatcg
     2281 ccccggtaag tgcagcctta tctctggata aggattcatt cattgcgttt aaagatgcct
     2341 gagccgcttt taatttctca ttctgattct gaatatcctt atcaagatag cgaacctgat
     2401 cctgccaccc ggagccatat tcatgaggcg ggttataagt cacaaaatca tctttatttg
     2461 cctctgcctc ttttaccttt ttatcggctt cctgaacagc agcccttgca ccggggagcg
     2521 ccttctctgt cgatgcaatg cggctgttta aggtcgcaat atttttatct tcggcatcca
     2581 gctcagcttt cgctttatca tagtctcttt tcagcccctc ttccggatga gcggcgtccc
     2641 atgcctgctg gcgacgcttt tcttcctcct gacgctgttt tacctgtgcc ggggtaagaa
     2701 catctgtcac cgacacataa accggcttct gtccggtctc tttcgggaaa cgaataacgg
     2761 cctcacggga gttaccaccg gctgtaaaac cagccggacg tgaatcacct ttttcagcaa
     2821 caatgccttt tggcggggct ttcgctgtcg gaacaccttt cggtacgctc acctgcagag
     2881 acgggagacc cggaatcgac acactgaata cccccggacg ttttgtcggt ttcgcatcca
     2941 ccacagggac actcattggc cgacctgcga caaccgcaat atgctgccgc tcatccttca
     3001 ccacatccac aacccgttgt ctgacacgaa ccgtcgcctg gtccagtggt aaagtacttg
     3061 ccggagtctc cgtcaccgca tcggccggta atgacgtcat aatttttgac atcattttcg
     3121 gatcatcttt tgcaatctca gaaggcagca caccgtagat cgcaatcccc cacagaccaa
     3181 acttaaacgg ccccttcagg gcagccagca catcagcaac ggcggccgac aacgcatcgc
     3241 cggaaactga taaagccagt ccttcagccc ccggagtagc cagggcaggc agaccgaagg
     3301 ccatcgcagt ggccgaagac tgtccgccac cagagctacc gctatgattg ccgctgttac
     3361 caccattacc accgggttta ctcccgccgt taccaaactc ccccggatta tagttatgaa
     3421 tatctccatt cggcgtatgc gtcgtacccc agcccggccc gctgtttgga tccgtaccac
     3481 cacctgatga agggccacct ttaccagacg taccgttcac attcccactg gcctgaccac
     3541 cattatgtcc cagacctgaa ttacccggac ctcgaccgtc tccaccactc ataccgtttt
     3601 cctctttgac atttaaaaca ataaattaaa gccaacatgt cgcggtaggg atacccgtta
     3661 ccggataccc cccgcacaga tcccggcgtg cgcgatttac gcaccgggct cctgcctcgg
     3721 gtgtctggcg gtgaaccgct ccacaggcca tggatgaaga acccgaaccc ttggtagcca
     3781 tgcggctgcc agtttgtttg ctttcgtcca ggtcgtatca tccttctggc tcctgcgcct
     3841 gagcgcccgg cgccagaggt ttgttacgtg tgtcctgaac ttctgcatgg tggggaagtt
     3901 gcccggtacc gagtgatagt tcaggtatcc ctgaaccact ctcctgagcc attttccctg
     3961 ttcggggatt gagtaatgcc agcgccttcg cagaccgtct ttgatggctt tcagagttgc
     4021 cgtcatccga tcccggcggg tctttcgtat cagcatgaac ctgccgttgc gatctttccc
     4081 gctgatgtgc gtgaacccga ggaagttgaa cgtttctggt ttgccttttc ccctgatggc
     4141 acggttttcg gcagcgaagc ggccgaactc catcagacgg gttttctccg ggtgaaccgt
     4201 gagtccgaac tccctcagtc tgcgctgcat ggctatacgg aagcgccggg catcgtatcg
     4261 tttgtcgaac ccgatgacga tgtcatcggc gtatctgacc attaccacat tgcctgtggc
     4321 atagcgacgt cgccactgat gcgcccacag atcgaagacg tagtggaggt atatgtttgc
     4381 cagcagcggt gagatgaccg caccctgtgg ggtgccttcc tccgttgctc gccattgacc
     4441 ctcctccgac gtcccggctg tgagccactt acgtatgagc ctgattaccc tccggtcgcc
     4501 gatccgatgc tctgtgaacc tgatcagcca ttcgtggctc accctgtcga agaactgact
     4561 gatgtcggca tccagtaccc agtttacgtt agtgcgtacc agccctgtgg ccagtgcgtc
     4621 cagtgcatcg tgctggcttc gcccgggtct gaacccgtat gagaacccca taaagtcgtt
     4681 ttcatagact gcgttcagga ttttcaccag cgcatactgg acgatcttgt cctccagcga
     4741 ggcgatgccg agcgggcgtt gttttccatc cgcttttggg atgtagtgac gcctgccggg
     4801 ctgcgccctg tagctgccct gatgtagcct ccggtgcaga tctgttatgt tgttcttcat
     4861 gtttccggcg tagtccatcc acctgatgcc atccactccg gcggccgctt tcctgctcag
     4921 ggagaggaat gcggcttcca gtgcttcgac tgtcagcagg tggaacaatg ctgtaaaccg
     4981 ttctttcttc cgctgcttcg cagcttcccg cacgcgtgac agcctctgtg acatgctttc
     5041 ccggctctgt gtccggcgca tgtgtggctg ttccgcgttc cccttggccc cgctccttcg
     5101 ctccactgac tccgctcctt tcgggttgtt cgcctgcttc gccgctacta tgagcgagtc
     5161 cgacttctcc tctccgtaca tcaccggcta tgactcctcg tcttcccggt gcgggccatc
     5221 tccgacactg gcagatggtc agaggggaga tctcccggtt cccgcgtaga gatcgtattg
     5281 acatgccagg gtctcagacc ccgccgggtc catgtggcac tcgcagtgtc gcaccctatg
     5341 atgttgcctt ccgttaacag tacaacgtcg gcacccggta atttaatata catttcgtgg
     5401 ctcaatggct ggcctgtcaa cacccctgtc aacgcttcgc cccatacctc gcggtatgca
     5461 acgcatgact cggggacctt gtggattgct ggtccttcaa tggtcgggga ctttcacccc
     5521 ttgatctcta accggtctcc cggcgcacac tgtacatata cacagtataa ttattacctt
     5581 actcctcccg ttttcaggtg tcaatatatg agattagttc tcatcttcag gcacaaaaaa
     5641 gcgcccggag ccacctgtaa gcagatcgcg tcttttcccg aaaatttctc atggcaacaa
     5701 attttattat ttaagacatt catcacactt acatttcaga tggtatagac acatctgaaa
     5761 gctaactggc atgaggagag gacctgcggt taaactgttc gggaaacctg agacgcccgg
     5821 aggccactat gacgcacctg aaactgactc ccgctgaaga aaagcgcctg gcggacgcct
     5881 ttgtcgctca ggcactggcc atgggcctga aagggaacaa aacgctgcca aaggcggtaa
     5941 aacaacaggt gcgggaaagg gtgcttcgtg ccattcagga cgaacgtgaa gccaggcggg
     6001 cgcaggaaat gcgtcgggag aaatacgagg ctacggaaac caccttcacc tggcagccac
     6061 agcgccgccg gtaaggggta tttaccataa cgtcgcattg cccgcaccgc tcagacggtc
     6121 tgagggcgtt tccggcggct acgggataaa acaggcaaca aaccacccgg aaaaccgccg
     6181 gaaacgcgcc cggtaaattg taacccgctg catgcctatg cacgcaactg catggcgggc
     6241 cgtttggtgt aaaaacgata cgataagccg tgtttatgta aatgaacgtg gccgtaaaga
     6301 gtgacaaata tacatgtaac attttttact gacaggtcat caacccgatg cgtttaatac
     6361 cctttatcct gctggcattg tgcagcccct tactcctgac ggcctgtaag cattccacca
     6421 cccagccgcc gaaaatttat actctggata agtcatctaa aatcagtagc tacgctgcgg
     6481 ccatcaagac cgctgttgaa atgcagatgt ttgaaccaga ggcctatgcg ggaaaaatgt
     6541 gcaccgtgcg gatatccata caacgtgatg gcactctgaa cagcgccatt gctgaaggag
     6601 gagatccgaa actctgtaaa gcagcaatat cagccgttac ccacgccaaa attccgccgg
     6661 caccggatga aaatacctgg caaatattca aaaacgcccc tctggatttc agaccatgaa
     6721 agcttttact ctgacagtgc tggcggccat gttcctcact ccggtacatg cgataccact
     6781 aaaacccgta accacactgc agccaaccta cccggtacag gccgcagcaa aacgcatcga
     6841 aggtcaggtg accgccacgt ttgatattct ggacgatgga cgagtggaca acgtgtcgct
     6901 taccggctgt cacctttttt ttcgggaaac gctgacggca atgaggcact ggctatatcc
     6961 cgcagggcac ccggcaatgc gacaggttat aaattttgaa ttcagtctga aaaatgacgg
     7021 cttacaggat ccgcgaccag tcaccaccca aaagctcaat gatgatggtt gccgccagta
     7081 acaggtcctt taacccgcag gctgcaatag tcctggatga tgagtgagcc tgtagcagcc
     7141 ctgattagtg gaagcgaagc tgaaaaatgg gcagcaaaag ccgtatttct ggcaaatagc
     7201 gccgccacgg attaaagtag tcatgtgtaa tacatatgac tacaaagggg cttttatgtc
     7261 atcagcaaca tccatcaggc tcgatgaaga acttaaggac cggctgaaaa cgctggccga
     7321 tgaccggcac cgctcagcgc acgcgctaat gctggaggca atcaccgaat acatcgaccg
     7381 ggaagagaag cgcagccagt acctgcggga cggacaggcc gcatggcagc actatcagga
     7441 aacgggtctg caccttactg cggaagaagc ggaagcctgg ataagtacct ggggaactga
     7501 gaacgagcag gatgctccgc catgccacag gtaacgattt ccgcgctggc acagcgcgat
     7561 ttacaacgcc ttcaggactt tctcaaaacc aaaaatcggc tggcagccag aaaaggaggt
     7621 gaggtgatcg tccgggctat ccagcaactg aaaacattgc cagacattgg ccgcccggtg
     7681 ccgtttctgc cgctggaata taaggaactg gtgatcgggt ttggcgacag tggctatgtg
     7741 atgctctacc gccacgaccg ggaaatggac cagattgtga tcgtcaccgt caggcatcag
     7801 aaagaatccg ggtatccggg ggcagacagc ctctaataac cgatgacggg ggcgcaattc
     7861 attgcgtggc cgtcgccggt ttgacaagcg cagcgcgtca gaaaaccaca tcctgaacgg
     7921 aaaaacgggt aaaattcagc gatacattta ccgtgagaaa ttacacacct ttcacacccg
     7981 ataaaatcag gggtatacag tggcgaaaac attgctcaac ctttcacagg cagcacaagc
     8041 cgcgggcatt accagaagaa cgctatacaa tcatgtaaaa cagggaaagg ttaccgtgtc
     8101 acgtgacggg aaaaacaacc ctgtcgtgga tgtgtcagaa ctgatccgtg tatacggaaa
     8161 tgtgaatatc cctgagaaac aaattcccgg catttcacac cgtgaaaata cacaaaaaaa
     8221 tttcccacag gaacagcttc tggcaatgca aaaggaactg gccgatctcc ggcaggctgt
     8281 caccctgatg ctggaagata aaacatcccg ggaagaagaa cgccgccagc acgatgatga
     8341 gcgccggaaa ctccaggccg aagtggacag attgacaaca gaactgacac agaagaaaaa
     8401 acgcttctgg tccggctggt ttagctgaga acttaccgaa gggaatggag aacatgacga
     8461 agcaggaaaa aactgccctc aatatggcta aattcattaa ggatcagtcg ctgctgttgc
     8521 tggaaaagct gaacgagctg gacatggata ccccggccga catgtgcgaa cggcttcacg
     8581 aggatgcgga aacactctgg caggtgatgc gggataagct cggggaagaa taacagcacc
     8641 ggccatgccg gtgctggcgt tattttttgc cgaacggcca ccaccggcgg gcgggtttgt
     8701 cctccggcag ttcaggcacc ggcacgttaa aatagcggct gttatattcc cgcatcagct
     8761 ccgctttcag cttctcgttc accgcgcttt ccccgtgccg ctcgctgacc acctcaatca
     8821 tcgcgttaat ctgctccggt gagcacttcc cggcatcaac cacctgcaca ccgttctcga
     8881 tggcgaaccg ctccaccttt cgatagaggt aatcacacag cttcattcct gtgggtttgt
     8941 cccgttccca ttgcggattt tcaccggtga aaaagtacgt ggctttttcg tcgctgttga
     9001 gccgctcgtc atacatcccg atggatttca tcatcgccag atgctgggcc cggtcgacaa
     9061 aacagaaaac atacgccccg gtctgccagg cgagcaccac catgtcttcc agatgctcgc
     9121 tggttggcat aatgcagcgc tcgccgtctt tgtcttccac gtcctcaata aataccatgt
     9181 acagcgccat aatccctcac tccgttgtca taaatttaaa gcacgcgaac agcctctccc
     9241 ggtccagctc caccgttttg cgggcctcgc cggtctgtgg attcacgatt tcatccaccg
     9301 ccagaatcgc ccgctgtacc cggacaagcg tcggccggtc agggcagatg taccagattt
     9361 catcgatgcc gttcgcccgg cggttgaaca gatacccgga caccacttcc tgataccgcc
     9421 tgcggctctt gacggtgcgc tctacctcaa atgccaccgt tctgccgtcc agctccgcca
     9481 gcgcgtccgg cactttcatc cctttcaggg ccatacggtg caggtaccgc cagccggtgg
     9541 ccccccggcc ctccatggag aggcgcaggg actgcacggc cagccggtgc ggcagctgcg
     9601 ccgccgacac ccttgacggc tgaaacggaa taacgtccgt cagcggctcg tcctcgtcga
     9661 acgagaacgc caccccgtgc ggcgtcagcc cccacacgct gacctgacgg ccgtcaaccg
     9721 ggtatttcgc ccggaccagc agccctttcg ccaccagact gtccaggaag cggtaaaccg
     9781 gctgtaccgc cgcaatcccc agccgtcgcg caaccagctc cgccgtggaa cacagctctt
     9841 cccgcagcca gcgcagggtc agccgtgttt tctccgcgtt ccgcgcctgc cgcttcgcgt
     9901 ggctgacgtt gtactgctcc agtgtcatca gtaaagcccc gcaaaatcat catccgcttt
     9961 tggtccgccg ccgtcggccg gaggcaggta ctccgccagc gggtccgttt tcgccagcac
    10021 cgggaaggtt ttcagcgaaa tttcccggcg ctcaacccgc agcgggctgc tgaacgccag
    10081 ccgcgccacg cccagcccgg tcatcaccgc gaacccgtca ggcaggtgtt gcagggtgtt
    10141 cacgtcaaac agcggccgcg cctccttctg gatgaagctg tcgccgctga tgtgctccac
    10201 gttccccgcc tcccggctgg cccggcggcg ctccacgtcc acccggatct ccccggtctg
    10261 gcccgccgcc cactgcgcgg actcctggct ggccgcgcga tagaaccagc ggatcggcgt
    10321 gttatccagt accgtggttt tcacaaaatc agcgggcaga tcctgcccgc actgaccgaa
    10381 gtcgcccagc gactggtgcg cgagcagcag gttgcagtcc cggctgcgca gcgtccccag
    10441 cgcgttcagc acgtacttcg acagcagata tttaatctca tcgagcatga tgctcgcgtg
    10501 cggccacctc cggaactcat cccgcgcaat gatgatttgc gcgcagcggg caaacagcat
    10561 cttctgcacc cggatcaccg cctcatcgtc catcgagccg atgacgtaca ggcagccgcc
    10621 gccgttgatt atccccgcca catcgatacc gctgtccgtc tgcaggacgc tcaggtcggc
    10681 cacgttctcc agcttggtga tcagcccctt cacgtccttt ttcagggcct ccggcaacgc
    10741 gtacgccgcc gccagcacct gctgaatgtt tgccccctgc gggaactgct ccgcaatcag
    10801 cttcgccgct ttctgctcgc tgatgcggta gtggtccgcc acgtcgccgg tctcactcag
    10861 gttaaacccg gcaaccagca gattcttcag ggcgtactgg tcgagatcgc ggaacagatt
    10921 cagctgcgcc ggtttccccg gccgcagatc cagcagggtg aagtccgggc agtgcgcccg
    10981 gaagacgtgc ggcgcccacg cgtccccttt ggggtcgaag tacaccacag cgtccccgaa
    11041 atcgcgtacg cagcgaatga gcgcgttggt ggccatcgcg ctcttgccgc tcccgggcag
    11101 gccgaggatc tgaatattgg tcttgcgcca ggtatcacga gggaccagca ccggctggcc
    11161 ctgctcatcc ttacccagaa acaccgcctg ctgtttccgg gcctgctccg tggaaaaatc
    11221 ggccagcgcg ttaaccggta ccggctcccc gaaatgcagg tggcggacgt ctgtcatttc
    11281 tccggtccgc tggctgctgc gccggctctc ctgattcagt ttcgcgttca ccgcctcgtc
    11341 agcggccgca aaatgaccat caagcagcag gaacgccagc agccgcgcca gaaggacgcc
    11401 ggcgacaagc cctccggcac accaggctat cccgaacagg ttagccggct gcagcaggta
    11461 ataatctgcg ttcgcataga ggtccgggcg caggacggtt tctccccagc tctcgataaa
    11521 cacggcgaca accagccccc ccagaagggc cagaccggca gcgccggtca gccagtacgc
    11581 gtagttccag acatgtcgcc gtgccctgac catccgcccg ggtgaatcca gcgaggccag
    11641 caccgaaaat ggcacagtcc ggttattatc gcgcttatag cgatcggcat actcccgccg
    11701 cgccttatgg ctcagcccca caaaacgcat tcggccggcc cagagttcag ccagaccgaa
    11761 aaacaggccg ataaccagaa aaaaaccggc cagactgtaa tactcccggt acagccagct
    11821 gacccacggg taaatctgcc gggccagctc cgggatatgc cactgccagg caagcgaatc
    11881 cgtattaaac atgcaatctc tctccttcag acgacgggtt taccggcgtg atgcgcagcc
    11941 cccgctgcac aagccgcgga catgccccaa
//
