LOCUS       NZ_MK450348            43125 bp    DNA     circular CON 09-JAN-2024
DEFINITION  Klebsiella pneumoniae strain K725 plasmid pNDM-K725, complete
            sequence.
ACCESSION   NZ_MK450348
VERSION     NZ_MK450348.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14229059
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 43125)
  AUTHORS   Tian,D., Zhang,H. and Pan,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2019) Clinical Laboratory, Shanghai Children's
            Hospital, Shanghai Jiaotong University, No. 24, Lane 1400, West
            Beijing Road, Shanghai, Shanghai 200040, China
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Sequencing Technology             :: Illumina
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/09/2024 03:00:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 60
            CDSs (total)                      :: 60
            Genes (coding)                    :: 53
            CDSs (with protein)               :: 53
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 7
            CDSs (without protein)            :: 7
            Pseudo Genes (ambiguous residues) :: 0 of 7
            Pseudo Genes (frameshifted)       :: 0 of 7
            Pseudo Genes (incomplete)         :: 7 of 7
            Pseudo Genes (internal stop)      :: 0 of 7
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MK450348.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..43125
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="K725"
                     /isolation_source="blood"
                     /db_xref="taxon:573"
                     /plasmid="pNDM-K725"
                     /identified_by="Dongxing Tian"
     gene            join(42686..43125,1..382)
                     /locus_tag="HTV72_RS00005"
     CDS             join(42686..43125,1..382)
                     /locus_tag="HTV72_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="WP_000196235.1"
                     /translation="MTRATERAYSELQQAFDFYNQRLFDGELPDCLITFQRGKNTMGYF
                     SYRRFVAADGSGRMIDEIALNPEYFPVYPLIEVMQTLVHEQCHMWQYHYGNPSRKTYHN
                     AQWAAKMESIGLMPSSTGRPGGAKVGQKINDYPIPGGRFQRVTLELFQGQFALSWFDRF
                     PVQVEQQKDMTAVIEQWRETLALAHQNAEAGIDIEAVLSMALLPSVSPQNGSHSDDMAG
                     SNDNDLSVAAFEDKPKRNKVKYQCRGCGAAVWGKAGLNIECGDCELAFIEN"
                     /name="SprT-like domain-containing protein"
     gene            492..746
                     /locus_tag="HTV72_RS00010"
     CDS             492..746
                     /locus_tag="HTV72_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000510385.1"
                     /translation="MGHYTIRTNDDEDQAIKKAQEATGQASASKTFMTAILELQRNRDE
                     MAQLRRELAQEKARSQELVSSVKQFRSSLNNLFDLADNP"
                     /name="hypothetical protein"
     gene            1036..1314
                     /locus_tag="HTV72_RS00015"
     CDS             1036..1314
                     /locus_tag="HTV72_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001093608.1"
                     /translation="MNTLAALENTFRDMRKHGCQTVMVTQSLADFGRYSYKPRPAFQDW
                     IERLKTGERLPRGRYFVGKKPGGRLVLIDELGGTWTEKVTVIHTNAG"
                     /name="hypothetical protein"
     gene            2119..2214
                     /gene="dqlB"
                     /locus_tag="HTV72_RS00315"
     CDS             2119..2214
                     /gene="dqlB"
                     /locus_tag="HTV72_RS00315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_000609145.1"
                     /translation="MINLLIIVLRAVAALANALIAILELIRQFID"
                     /name="dqlB"
     gene            complement(2367..>2939)
                     /locus_tag="HTV72_RS00025"
                     /pseudo=""
     CDS             complement(2367..>2939)
                     /locus_tag="HTV72_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            3083..>4489
                     /locus_tag="HTV72_RS00030"
                     /pseudo=""
     CDS             3083..>4489
                     /locus_tag="HTV72_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490160.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element IS3000 family transposase"
                     /name="Tn3-like element IS3000 family transposase"
     gene            complement(4636..5616)
                     /locus_tag="HTV72_RS00035"
     CDS             complement(4636..5616)
                     /locus_tag="HTV72_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416498.2"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS5 family transposase"
                     /protein_id="WP_000019402.1"
                     /translation="MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFY
                     PKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTT
                     IMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPE
                     MHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAG
                     YQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVEHPFRI
                     IKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH"
                     /name="IS5-like element IS5 family transposase"
     gene            5851..6663
                     /locus_tag="HTV72_RS00040"
     CDS             5851..6663
                     /locus_tag="HTV72_RS00040"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="WP_023408309.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQR
                     FGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQILNW
                     IKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHSLTF
                     AANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLG
                     DADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
                     /name="subclass B1 metallo-beta-lactamase NDM-5"
     gene            6667..7032
                     /gene="ble"
                     /locus_tag="HTV72_RS00045"
     ARG             6668..7029
                     /name="ble"
                     /gene="ble"
                     /gene_name="bleomycin binding protein Ble-MBL"
                     /tool="amrfinderplus"
                     /drug_class="BLEOMYCIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            7037..7675
                     /locus_tag="HTV72_RS00050"
     CDS             7037..7675
                     /locus_tag="HTV72_RS00050"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /GO_function="GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="WP_004201168.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVAG
                     ALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKPVW
                     KALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALPWGL
                     AGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
                     /name="phosphoribosylanthranilate isomerase"
     gene            complement(7686..>8243)
                     /locus_tag="HTV72_RS00305"
                     /pseudo=""
     CDS             complement(7686..>8243)
                     /locus_tag="HTV72_RS00305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006399920.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
                     /name="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
     gene            complement(<8343..8717)
                     /locus_tag="HTV72_RS00310"
                     /pseudo=""
     CDS             complement(<8343..8717)
                     /locus_tag="HTV72_RS00310"
                     /inference="COORDINATES: protein motif:HMM:NF022853.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD
                     domain-containing protein"
                     /name="protein-disulfide reductase DsbD domain-containing
                     protein"
     gene            complement(8722..>8835)
                     /gene="cutA"
                     /locus_tag="HTV72_RS00060"
                     /pseudo=""
     CDS             complement(8722..>8835)
                     /gene="cutA"
                     /locus_tag="HTV72_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201171.1"
                     /GO_process="GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /name="cutA"
     gene            <8852..9466
                     /locus_tag="HTV72_RS00065"
                     /pseudo=""
     CDS             <8852..9466
                     /locus_tag="HTV72_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(9500..9856)
                     /locus_tag="HTV72_RS00070"
     CDS             complement(9500..9856)
                     /locus_tag="HTV72_RS00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="WP_004199403.1"
                     /translation="MGFPSPATDYQENRLSLDQHCNTGAPGVFFFRSDTYSFREGIKPG
                     ALLIVDFGGTPVDGSLVLCVLEQEFRIMRLRLHPKRCLQELDKLDNFRAIPDDDEDGLE
                     VRGVITHIVALLQS"
                     /name="S24 family peptidase"
     gene            complement(9859..10098)
                     /locus_tag="HTV72_RS00075"
     CDS             complement(9859..10098)
                     /locus_tag="HTV72_RS00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001549892.1"
                     /translation="MPRHYEIDSAWRASIKREPNGRQTVTTEAFVSQLALINFHWSCRQ
                     ANQWIETYVTVFKDISTQEGENRTFMLFNPNGGR"
                     /name="hypothetical protein"
     gene            10200..11420
                     /locus_tag="HTV72_RS00080"
     CDS             10200..11420
                     /locus_tag="HTV72_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343760.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISKox3 family transposase"
                     /protein_id="WP_000343760.1"
                     /translation="MDEKSLYAHILNLSDPWQVKSLSLDENAGSVTVTIEIAENTRLAC
                     PTCGKSCSVHDHRHRKWRHLDTCQFTTIVEADVPRIMCPEHGCLTLPVPWAGPGSRYTL
                     LFESFVLSWLKISTVDAVRKQLKLSWNAVDGIMTRAVKRGLARIKKPLSARHMNVDEVA
                     FKKGHRYITVISDRDGRALALTDDRGTESLAGYLRTLTDGQLLAIKTLSMDMNAGYIRA
                     ARIHLPSAVEKIAFDRFHVAKQLGEVVDKTRQNEHPHLPVESRHQAKGTRFLWQYSDKW
                     MTESRQEKLMWLRAQMKLTSQCWALKELAKDIWNRPWSEERRSDWQRWLALAANSDVPM
                     MKNAAKTIGKRLYGILNAMRHSVSNGNAEALNSKIRLLRIKARGYRNRERFKLGVMFHY
                     GKLNMAF"
                     /name="ISL3-like element ISKox3 family transposase"
     gene            complement(11509..12171)
                     /locus_tag="HTV72_RS00085"
     CDS             complement(11509..12171)
                     /locus_tag="HTV72_RS00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549893.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001549893.1"
                     /translation="MTQTVPKGFVRAYLRASTTEQDATRALDTINTFAIERGLSICNYY
                     IENESGSKLERPELFRLLKDCQQNDILLVEDVDRLSRLVGEDWNTLKKMIRQKDIRVVA
                     VNVPTTWLASGHNDFDSRMFSAINDMLLDMLAAVARRDYEQRRERQQQGIARAKREGKY
                     KGRQVNQSRYDAINRLIASGSSWSQIQKVLGCSRATISKAVKQQTVNKMNHEPEGRE"
                     /name="recombinase family protein"
     gene            12552..13214
                     /locus_tag="HTV72_RS00090"
     CDS             12552..13214
                     /locus_tag="HTV72_RS00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            13314..13598
                     /locus_tag="HTV72_RS00095"
     CDS             13314..13598
                     /locus_tag="HTV72_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001185481.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVAGKPKLMNFRL
                     PAYFEEILEAEAQRTGQSKTTVLKAALAAFDNLDENLKNHWLLESAKLG"
                     /name="hypothetical protein"
     gene            13873..14115
                     /locus_tag="HTV72_RS00100"
     CDS             13873..14115
                     /locus_tag="HTV72_RS00100"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223286771.1"
                     /translation="MFLIGIGLWGFYAPDEGTCTNLNIELCAVSAIDVLKPAIFVFLGI
                     ITVAGWYFTELQPKLRGEGKYMKVKTGVKPEDFVK"
                     /name="hypothetical protein"
     gene            14151..14435
                     /locus_tag="HTV72_RS00105"
     CDS             14151..14435
                     /locus_tag="HTV72_RS00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001043731.1"
                     /translation="MNKSWLEQQVQNEKLKKVQEEKKDGTIQKGLYRVRIKDKYRWDLW
                     ENDFRVVIAYSKDDAELKFTEMTGFNEHYYIESIEKIVLSDIEKILLEN"
                     /name="hypothetical protein"
     gene            complement(14456..14809)
                     /gene="ddp1"
                     /locus_tag="HTV72_RS00110"
     CDS             complement(14456..14809)
                     /gene="ddp1"
                     /locus_tag="HTV72_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_000877224.1"
                     /translation="MKYQVKEFINEKYSKAVNILKDNLKEHYHIFYGLRLSEILFPASE
                     YGSEMFFQEFEAINSVILPLVIFDLIDRKPIMVIGFGEVCGVDSLVDSGIEVVSLDGLS
                     DLLLVEKLTPLFN"
                     /name="ddp1"
     gene            complement(14997..15440)
                     /locus_tag="HTV72_RS00115"
     CDS             complement(14997..15440)
                     /locus_tag="HTV72_RS00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001074369.1"
                     /translation="MAKIYEFPQGAERSKLKKEIIRERKKRLRETNGNPVIRHAKWFWF
                     YLRLATAGALHLVSVISLAVLGAFSKAIFWIGGMLCVVTWFHLERQFWTPQNFTIPVIV
                     TLWGLSLFATPLMELLNKKMPWYRLLVPDAKHTSTEATNDDQP"
                     /name="hypothetical protein"
     gene            complement(15449..16462)
                     /locus_tag="HTV72_RS00120"
     CDS             complement(15449..16462)
                     /locus_tag="HTV72_RS00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348704.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001348704.1"
                     /translation="MRLLLSLDMKILRSSYLKVRGFLIKGCIVVLNYNLCGVMICLHRK
                     GYMRLIVKTVTGLTKVRHRNEVGVTLASLSLSAKRVLFLALCQIDTKEMLDDDILEVDA
                     DFFSKATSLDKYASYAALKEGAKVLSSTTLVLNRDDLKNLADELGILSSKNKIPDRLDL
                     NLTEFCAYYDHLATVRIKFTNTAKRYFSKLIGSENRYTTQVLKSVVLLNSVNSTNLYQV
                     IRKYYSQNSSKKSFDISVDDLKEEMGLYTIEEGEKKYKYPKYSFFVRDVINKSINEIIE
                     KTEINQLSFSVVGKKGRMAHMLRFEFSINEKSSSFSEDDMAFLEEFDKVVPPKKNK"
                     /name="replication initiation protein"
     gene            <17023..17175
                     /locus_tag="HTV72_RS00125"
                     /pseudo=""
     CDS             <17023..17175
                     /locus_tag="HTV72_RS00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /name="DNA-binding protein"
     gene            17765..18280
                     /locus_tag="HTV72_RS00130"
     CDS             17765..18280
                     /locus_tag="HTV72_RS00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="WP_001025390.1"
                     /translation="MNIQEALNVFGLSGDLTEKDIKAAYKKAALKYHPDRNPLGAELMK
                     AVNAAFDFLMANIDKINQFQSTDENARYNYGEDLEKVLNTLSGLTGIVYEVIGNWVWIS
                     GETKEHKDILKEMGCKWASKKKQWFYRPEEHKSRWNRKEHSIEEIREMYGTAGKRKASG
                     WTRVEASA"
                     /name="DnaJ domain-containing protein"
     gene            18339..18575
                     /locus_tag="HTV72_RS00135"
     CDS             18339..18575
                     /locus_tag="HTV72_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000792381.1"
                     /translation="MKNKTITEAELINIFESYGAYICPDEIEVTAKECNENGSVLHRGL
                     NAEGWAHLFAKEEAYQQECEAQEAASDDGHFDE"
                     /name="hypothetical protein"
     gene            18635..19186
                     /locus_tag="HTV72_RS00140"
     CDS             18635..19186
                     /locus_tag="HTV72_RS00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000662998.1"
                     /translation="MKEQKNFFERYKPVFEIVCRILGNGWRVNLLDDCQYRIKLTSPDF
                     KNYSIHIRMEKGRLVIIGSVDSRSWRSPYHTCTVSPERNPVEIAADIEKKILSDALDNV
                     DMAREYEQQLQQKREKKLILKGMLSRLVHLESWHGTLTGFKVENGLDGNVSERGDGYEM
                     VIRGLSVDQLIKVAGFIKQL"
                     /name="hypothetical protein"
     gene            19183..19464
                     /locus_tag="HTV72_RS00145"
     CDS             19183..19464
                     /locus_tag="HTV72_RS00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001348701.1"
                     /translation="MRQKMNEVLSDRKNKGNVTYRIVVSEDATRLFIELEKLMKVRSKE
                     ADKKTTKKIVFQKSFYYEEFSNVKDEIDDPILLKFYTDTIVKVQNHEF"
                     /name="hypothetical protein"
     gene            19454..19696
                     /locus_tag="HTV72_RS00150"
     CDS             19454..19696
                     /locus_tag="HTV72_RS00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000008707.1"
                     /translation="MSFKPTPEEVKQARIKAGFTQQEAAERFGFTLSAWQAKETSGKTS
                     RGLAAGTYELLLLLADEHPDYQLVKREKNQDKVTK"
                     /name="hypothetical protein"
     gene            19790..20128
                     /locus_tag="HTV72_RS00155"
     CDS             19790..20128
                     /locus_tag="HTV72_RS00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001099725.1"
                     /translation="MNTYVITFQALNTKKEKITCSAFVHSETLFLAVHSFEDKNRGRGY
                     VITSVSELLSEELTAKNSLKKNINFWFNECGLSKSEVINEVINWKNFAYTLKELEEAKN
                     EAIRELRS"
                     /name="hypothetical protein"
     gene            20215..20367
                     /locus_tag="HTV72_RS00160"
     CDS             20215..20367
                     /locus_tag="HTV72_RS00160"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_162542717.1"
                     /translation="MLSAIQTVEKGGRPVFPLMPFSAFPEYMALLRKALEKKETKALIE
                     KQEVL"
                     /name="hypothetical protein"
     gene            20364..20621
                     /locus_tag="HTV72_RS00165"
     CDS             20364..20621
                     /locus_tag="HTV72_RS00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004199355.1"
                     /translation="MKKQEFLDFISAEQRRGAVRFSLGFNSKGEIVLHWTNEAGLRVWS
                     ILSGNRGKSPSRANRERMSNLRRWLHDARQGMEGDTPEAE"
                     /name="hypothetical protein"
     gene            20962..21507
                     /gene="ddp1"
                     /locus_tag="HTV72_RS00170"
     CDS             20962..21507
                     /gene="ddp1"
                     /locus_tag="HTV72_RS00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_001348698.1"
                     /translation="MKKVQFRIEESQHDDLLDCLKTLYPDEPGLTVAKGMKLLANALLK
                     SKVKNEDVNVSKDNDDFIKTTMYLTGKQRTLIEKAAHRHGWNLSRECRYRIQTTLENEL
                     DFFDQELLVMNRCRNAIDKIGRNFHYIIVNDNARVLDKDGFYQDAERLSSEIMSLKSEF
                     ENYIMLCKGRTVSNKVEV"
                     /name="ddp1"
     gene            21510..22670
                     /gene="mobP1"
                     /locus_tag="HTV72_RS00175"
     CDS             21510..22670
                     /gene="mobP1"
                     /locus_tag="HTV72_RS00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP1 family relaxase"
                     /protein_id="WP_004199101.1"
                     /translation="MGVYVDKEFRVKRKSSEAGRKSAFAHKVKNGGKNYQRNVQERINR
                     KGASKEVVVKISGGAITRQGVRNSIDYMSRESELPVMSESGQVWKGDEIQEAKEHMIDR
                     ANDPQNVFDDKGKENKKVTQNIVFSPPVSAKVKPEDLLESVRKTMNKKYPNHRFVLGYH
                     NDKKEHPHVHVVFRIRDNDGKRADIRKKDLREIRTGFCEELKMKGYDVKATHKQQHGLN
                     QSIKDAHKTAPKRQKGVYEVVDVGYDHYQNDKTKPKQHFIKLKTLNKGVEKTYWGADFG
                     ELTTRENVKKGDLVKLKKLGQKEVKIPALDKNGVQHGWKTAHRNEWQLENLGVKGIDRI
                     SSSSKELVLNSAEMIKKQQLQMRNFSQIKQSMIQSEQKVKIGIRLG"
                     /name="mobP1"
     gene            22882..23532
                     /locus_tag="HTV72_RS00180"
     CDS             22882..23532
                     /locus_tag="HTV72_RS00180"
                     /inference="COORDINATES: protein motif:HMM:NF014417.4"
                     /GO_process="GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]; GO:0140673 -
                     transcription elongation-coupled chromatin remodeling
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_004208545.1"
                     /translation="MRSKDLLVWLNAAHVADKVFMRCKFVLLFFFSDSGSSESRERLKG
                     KTMEWYVLQFTTTRFAAVFAHLERLNFSYFCPMETERYRRPDKIISYRERRLPLFPGYL
                     FIQADFEEVHSTTITAIPYVQRFISFGGEPLPVPEDVMAELLYRQSHTTAQANLLRKSI
                     PHDFAEILLMDNPQQRSMAFIHYITERSLTHKMKRKKNDCYPKKNRNETQAPT"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            23483..23719
                     /locus_tag="HTV72_RS00185"
     CDS             23483..23719
                     /locus_tag="HTV72_RS00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001348696.1"
                     /translation="MTATRKKTATRRKPQRNTLYLPSASREELDKIALEIGYRRGRRIS
                     SSGVVQYLIKKYSSQAIEELINEDDEDDDDFDD"
                     /name="hypothetical protein"
     gene            23765..24409
                     /locus_tag="HTV72_RS00190"
     CDS             23765..24409
                     /locus_tag="HTV72_RS00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000953538.1"
                     /translation="MLSTTAFAALALQCAASVHPDTAHEVARVESGFNPYAIAEIIPKV
                     ERKPGDKGVVSYFPKTKEAALQIVNQIESRNHRYSVGLMQITSTNFANFNTTAEKMFDP
                     CENLKVSEQILVDCYKRGGDILRGLSCYYSGNPETGTKPESDFNNTSYIQRIGFNPPDN
                     KKNWVVPSVKDAIRKENVTQSIKPKEVTVYPQYAMRGTVLDEKETNDVKTQ"
                     /name="lytic transglycosylase domain-containing protein"
     gene            24393..24683
                     /locus_tag="HTV72_RS00195"
     CDS             24393..24683
                     /locus_tag="HTV72_RS00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000916156.1"
                     /translation="MLKLNKRYLTLSVFMAALMLCVAEPAFADDVSTKTTGFLQKIIDF
                     LTDIRKPAITIIALVIGYIAIFSRQHAAWITPLIIGIIIFIVAPYLPDWLA"
                     /name="TrbC/VirB2 family protein"
     gene            24708..27461
                     /locus_tag="HTV72_RS00200"
     CDS             24708..27461
                     /locus_tag="HTV72_RS00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_015060057.1"
                     /translation="MSTVFKGLTRPALIRGLGVPLYPFLGMCVICVLLGVWIHEAMYAL
                     ILPGWYAIKRVTKIDERFFDLLYLRMQIKGNPLANKRFNAVHYAGSSYDAVDISKVDNF
                     MKLKDQSSLEELIPYSSHITDNLIVTRNHDLLATWQIDGAYFECVDEADLALLTDQLNT
                     LIRSFDGKPVTFYTHRIRVRKEVRPVFDSKIPFVNRVMNDYYESLSAAEYFENKLYLTV
                     CYKPFSAEDKVTHFLSRKKGNKNIFEEPINDMNEICGRLSTYLSRFHSRRLGLYEENNI
                     VYSEQLTLFQKLLSGRWQKVRVTNSPFYTYLGGKDLFFGNDAGQITASDHARYFRCIEI
                     KDYFQETDAGIFDALMYLPVEYVQTSSLTPIDKQSAIKALDDQIDKLEMTDDAAKSLLA
                     DLKVGLDMVSSGYISFGKSHQTLIVYADSPERLVKDTNIVTTTLEDLGLIVTYSTLSLG
                     AAYFAQLPGNYTLRPRLSSISSLNFAEMESFHNFFTGKEKGNTWGNNLITLGGSGNDIY
                     NLNYHMTTEHQNYFGKNPTLGHTEILGTSNVGKTVVMMTKAFAAQQFGTPESFPPERKL
                     KKLTTVFFDKDRAAEPGIRSMGGAYFRVKEGEPTGWNPAALPPTKRNISFMKDLVRLLC
                     TLNSEPLDDYQNRLISDAVERLMQRSNRSYPISKLRPLILEPDDTETRRHGLKARLNAW
                     VQGGEFGWVFDNPDDTFDVDNLDVFGIDGTEFLDNKVLSSAASFYLIYRVTMLADGRRL
                     LIYMDEFWQWINNEAFRDFVYNKLKTARKLDMVLVVATQSPDELIKSPIAAAVREQCAT
                     HIYLANPKAKRSEYVDELEVRELYFDKIKAIDPLSRQFLVVKNPQRKGESDDFAAFARL
                     DLGKAAYYLPVLSASKPQLELFDEIWKEGMKPEEWLDTYLERANLI"
                     /name="VirB3 family type IV secretion system protein"
     gene            27471..28241
                     /locus_tag="HTV72_RS00205"
     CDS             27471..28241
                     /locus_tag="HTV72_RS00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000716326.1"
                     /translation="MKKHIVAALIASVTVISGAQAGVPVAIDANPEWAVEAQRWTERLK
                     QWQDTVNHYQKQINAYKQELLTKTGIRDVQGLVQSAQSVSKELENIYDQGNSFIDDYIK
                     NPEATLSEQARSLLADYKVTNTCKGLGYTGDLVRGCEASFLSQLAGIEYGNKLESKLRE
                     DNQEMADLIDQVKNAQDTKATQDATNAVSLASLKFNKLKFQYEMYRDKQRDLAEYKEKM
                     LQAAFQEKQLGAVNKETPVVDYKAAFEQQSYEMN"
                     /name="type IV secretion system protein"
     gene            28251..28508
                     /locus_tag="HTV72_RS00210"
     CDS             28251..28508
                     /locus_tag="HTV72_RS00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000759841.1"
                     /translation="MKKYGLVAALGLTFFLTGCEEVKSVDWWQSHVDDATKKVAECKKS
                     GSDSENCKNAKEGLFRYKQLHPKHVDYKDAFKNVLGKDGS"
                     /name="EexN family lipoprotein"
     gene            28520..29575
                     /locus_tag="HTV72_RS00215"
     CDS             28520..29575
                     /locus_tag="HTV72_RS00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000235886.1"
                     /translation="MATSRYFQAAHDVIVKTLDQSLTGQLDNFSSIASQLGKYGISIYI
                     LWYAYTTIVGKQKTAVQDFLWNLCRFWLILVFVKNMGGWLDSATQAIDGLKETFAGGDP
                     WKWVDELWEKVQQVAAYLMSKDTSKYVKTDGAIASLLTYAGGIIALLLTSIVYLAAEVT
                     IKILTITAPLFIICLSFGFLRQMFNSWLQLIFSSCFIFLFCGLAIKAGMTFLNGILTIS
                     IANADELNLISTGAQAGVAGAFMAWIIWQAKTYASQLAGVGVEGAMQGAAAMGIGAGVF
                     GASRMGRNLLGMGKNAGIGAWKGVRRQDGGFNQSPGVSGKLGNLTGQGVNIGAKRLRQA
                     AIDAAKKKYGG"
                     /name="type IV secretion system protein"
     gene            29770..30498
                     /locus_tag="HTV72_RS00220"
     CDS             29770..30498
                     /locus_tag="HTV72_RS00220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_004199085.1"
                     /translation="MGFKLSGLKLPGFNKKKEVTDSSTTFEEKNVLMQEKMNRIYKFGG
                     IAGIAVGVLSLLALNGALPLKSTVVEAYLINGVTGVAERLTSVKKENLSENEALAKYFI
                     TQYVKRREGYNYFSLQHDYDYVLLYSAENVATDYNALINGNQSPKVIYNKAEKTASVQD
                     NPSVIISPSSRRDDKDMGAYIRFKLTIRNVATGQDDYEYWNVRLTYRIEPQVEMASGDR
                     NNNPLKFVVTSYVRDKEVKG"
                     /name="type IV secretion system protein"
     gene            30504..31433
                     /locus_tag="HTV72_RS00225"
     CDS             30504..31433
                     /locus_tag="HTV72_RS00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000783379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_000783386.1"
                     /translation="MKMNKGALIVALLLVSHVCHAAVTPAASRFDPRNQIVSYNPQNTT
                     VINSAVGYTTTLVFDEDETVISARTGFPQGWEVNKEDNLVYLEVKPVKQTVQKNSTDDN
                     GNQSSEVVSVALDPENDLERWRTNLFVRTTKRNYSMELNARTFRQPDKIAFVVNYQYPQ
                     ERRKEQAEIEKKRIEALNKRQEEQAINRSLENAKSPKNWDYWKRVADGSQSISPDYAYD
                     DGRYTWFGFSPLKKIPSVFVMSGEQETLTNPVVKNSGSFTVVGVPVDQRFVLRMGNQVV
                     GVENRGFGKVRLPAGDTVSPNVEKEVIQ"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            31430..32644
                     /gene="virB10"
                     /locus_tag="HTV72_RS00230"
     CDS             31430..32644
                     /gene="virB10"
                     /locus_tag="HTV72_RS00230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_001295060.1"
                     /translation="MSEQENKIPTAVEIEQALRERHQKEIEQNDKTDKGDEDDGKSVKR
                     LGIEKLKKSRKGLVIIVAAFLLLAAGVSVYYIPSIIRAMSSGDDKPASNAVSTGSVKRA
                     TGLSDDVDPFNTREEPAKTEERKESSGKAETPPEKVQQNFSRALDVAYGGSSSASSNSG
                     GSSSTASNTRNEGDGSDKQAEVQPVNAGQPAQLSKITRVPYDPNLFIPENTAIKCSLDR
                     RFISDLAGKLVCTINEDVYSANRNVKLIEKGTAAYLMYKTGTFNHGQGAVFIAATKLRT
                     RKEPFIDIPLIDTQAAGALGEAGASGWIDTHFADRFMGAMMVGMIPDVAQAASGAAKSN
                     KDNQTDYTANSRQAFADIAREAFANSVNIPPTLYKNQGEIITLIVGQDLDFSSIYKLKM
                     VGTRR"
                     /name="virB10"
     gene            32646..32843
                     /locus_tag="HTV72_RS00235"
     CDS             32646..32843
                     /locus_tag="HTV72_RS00235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000629109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="WP_000629109.1"
                     /translation="MITLDIKEFSMLLGIRESEIYHHIRKGIPINGVPFPKPLKQIKTH
                     RFNYEEVMRFIEDLKGKGEL"
                     /name="DNA-binding protein"
     gene            32840..33874
                     /gene="virB11"
                     /locus_tag="HTV72_RS00240"
     CDS             32840..33874
                     /gene="virB11"
                     /locus_tag="HTV72_RS00240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549925.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000650512.1"
                     /translation="MKDAENRHIVYEIIDEYFHHWLNEVDGLTEIAVNRPDELFVKVSG
                     KWQQHELKMDFKDCMSFAGAISDYHDGGSVTPEYPLRSVTLPGGERVQIVIPPATERET
                     VSITIRKPSSVFIDHDTFVKQGFYSRLNQGGKFRDKEDELSSMFKDNCFEQFVPECLVK
                     GKTMVFCAGTGAGKTTFANACLQYIPHHLRCISIEDTDEAKFRFHKNHVKLYYPSEGES
                     STVSSASLLRSGFRMNPDRILMTEVRGAEAWDFLKGSSSGHAGNLTTVHESTPEDAVLG
                     LVQRCYMNPECQNLPYNIILRRVLSNVDVIMSIKYIDEEDNRFASGIYYRDIHFQEYFE
                     KLKE"
                     /name="virB11"
     gene            33877..35712
                     /locus_tag="HTV72_RS00245"
     CDS             33877..35712
                     /locus_tag="HTV72_RS00245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053816.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_000053822.1"
                     /translation="MSLKLPDKGQWAFIGLVMCLVTYYTGSVAVYFLNGKTPLYIWKNF
                     DSMLLWRIITESNIRTDIRLTAIPSLLSGMVSSLIVPVFIIWQLNKTDVALYGDAKFAS
                     DNDLRKSKLLKWEKENDTDILVGAYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPNLLV
                     RKHSLIALDPKQELWKITSKVREKLLGNKVYLLDPFNSKTHQFNPLFYIDLKEESGAKD
                     LLKLIEILFPSYGLTGAEAHFNNLAGQYWTGLAKLLHFFINYDPSWLGEFGLKPVFSIG
                     SVVDLYSNIDRELILSKREDLEGTKGLDENALYHLRDALTKIREYHETEDEQRSSIDGS
                     FRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDMSLAYDFLNLFFNFVVE
                     VTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNE
                     IYGVEGAKTLMSAHPCRIIYAVSEEDDAKKISEKLGYITTKSTGSSKTSGRSTSKSSSE
                     SEAQRALVLPQELGTLDFKEEFIILKGENPVKAEKALYFLDPYFMDRLMMVSPKLTELT
                     ASLNKTKKVLGVKGLKYPSKEKMLSVGELESEVLL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            35709..36101
                     /locus_tag="HTV72_RS00250"
     CDS             35709..36101
                     /locus_tag="HTV72_RS00250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_000738524.1"
                     /translation="MKKMLMVSVLFLSACSSPPEPPQVDWEQNPETVNTQLMDWQPTYS
                     VIKSDKVNSSWVKVIHNFRPENRLYDDAVFYSVAHSDSVIVETSNGTDFFTAKNWLRAN
                     GANGVIQYRYKMNCFSCRTTSVYLSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            36189..36503
                     /locus_tag="HTV72_RS00255"
     CDS             36189..36503
                     /locus_tag="HTV72_RS00255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000754496.1"
                     /translation="MKKTVTTAVLLCAFAAGTAHAEEKADPNDPCAMVLCLAGKLDGSS
                     PAECDPMYKSFMSIRKKNKHGFLPDHTADARKKKLNECPAADAGTVSKIISSFGRLKNF
                     "
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            36589..36915
                     /locus_tag="HTV72_RS00260"
     CDS             36589..36915
                     /locus_tag="HTV72_RS00260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004208538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004208538.1"
                     /translation="MKIINVPDARSVRIAGIEIIDSVKSVASVFTEILLFMVWFPAIVY
                     GLYRFVIVLWDASLKPQSLIEFINFMVELYSYVLPSLAVIAVALVVVLSIFKRLSAIWE
                     GRKQ"
                     /name="hypothetical protein"
     gene            36912..37406
                     /locus_tag="HTV72_RS00265"
     CDS             36912..37406
                     /locus_tag="HTV72_RS00265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001215543.1"
                     /translation="MRHFFNVLSFAVALLPATLCAAQIQGKVIRVLDGDTIEVKTLPAK
                     IVVYEVPIRVRLINIDAPEKKQPFGRWSTNQLKALLAGQSVTVSYTQTDRYGRVLGRVV
                     TANGTEANRQQVLKGAAWVYDRYNTDNSLPALQREAQTQKRGLWADSNPVPPWEWRHKQ
                     N"
                     /name="thermonuclease family protein"
     gene            37489..38751
                     /locus_tag="HTV72_RS00270"
     CDS             37489..38751
                     /locus_tag="HTV72_RS00270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_000517490.1"
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRKN
                     RKIYSNLDIEPVASTVVHTGSSPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIRFI
                     LNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKIGCYDGVYYHGKARKEE
                     IENALRFSVHPKFNELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIAKALG
                     AKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGADTPRN
                     LAGTYVIFSTNYPNRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPDDINIDLKE
                     LGAVLDRTTPAEIKEIINIAIGMIRGTKNELTVDVIKNARAFLKGTLDLSVQEAEEDIE
                     EREEIFKKNGAQPDYSSYLED"
                     /name="ATP-binding protein"
     gene            38755..41082
                     /gene="topB"
                     /locus_tag="HTV72_RS00275"
     CDS             38755..41082
                     /gene="topB"
                     /locus_tag="HTV72_RS00275"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549937.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003917 - DNA topoisomerase type I (single strand cut,
                     ATP-independent) activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_004199098.1"
                     /translation="MRLFIAEKPSLAKAIFEGLGGNPNTEKKNGYFEHGSDVVTWCYGH
                     MLELYDPQDYDDKYSNWRYSDLPIKAVYPPKYKIKPESEAQTRIILSLIDKADSIVHSG
                     DPDDEGCLLVDEILGYAGNKKPVQRLLVADLNLAPVQKSLSNLQPNDKFRGMTLSALAR
                     SLCDQGFGYNMTRGCTLKGREKGYDGVLNVGRVQSAVLGLVNMRTLANQNHTESFYYDV
                     FASLSMNGHQIKAKYQTTDDDQIDEKKRLISEAQAAHIAGRVTGKDAIVTIATTKPENS
                     KPPLPLNLSTLQQLCAKRFGYSAKDTLDVMQGLYETHKLLTYPRSDNRYLSDEHYYQAG
                     DIATAIAATVPELASAIVDMDKGQKHKAFNASKIEAHHAIIPTTKSGAGIQLNEKERNV
                     YNLVSVYFIGLFYPDAIRNKTKIHFDIKGDTFTATQSVLVQKGWEALGKDSDDEDETED
                     AGTDGFDLSLLKFNDSGLCESADVDKKKTTPPRYFTESTLLAAMTSAAKFIDDPALRKA
                     LEAKDEGSSDRGSIGTEATRAGILEKLAANTGLISIEKEKGYSELVWKTTKQGQEFCAA
                     LPPEITKPDISALWAEKQSQIKAGELTVEEFIKENDEYVQGLIDELDRNGISISSNATP
                     CPVCNNGFLRKRKGQNGFFWGCSCYPECKTTFPDKDGKPDMEAKSRSEGSMSRLEAPCP
                     SCSKEIIIRPKGFFCSGCEFKIWSEVSGKKLTQNQVETLIKKGKTGEIKGFTSNKTGKK
                     FDAAIVLQDKTTGKLGFQFSKK"
                     /name="topB"
     gene            41094..41549
                     /locus_tag="HTV72_RS00280"
     CDS             41094..41549
                     /locus_tag="HTV72_RS00280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549938.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293458.1"
                     /translation="MSENETFDATKKLLLNIRSVRVFARETSFEQLLEMQEKLNAVIEE
                     RREEAEREAAERAERERKRQELLQLIAGEGFSPEELLGLSEDAQKTRKKTLPKAPPKYQ
                     FDENGETKYWSGRGRTPKPIDEALKAGRSLDEFLIKKDASSTAGDEQ"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(41587..42237)
                     /locus_tag="HTV72_RS00285"
     CDS             complement(41587..42237)
                     /locus_tag="HTV72_RS00285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242661.1"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="WP_000351937.1"
                     /translation="MDIKPNSVIHLEPGETLPGYTNLKPVPDKYFDELKALINKLNTQS
                     GNIYLKLKQMYAFLDRFNKEFVSTFTSCQKGCSSCCKMDVHLTALEATHIAQASKLTAR
                     DNPLTTGHESKCPFLSEKGTCSIYNYRPLLCRTYHVLTPPEMCNDLDAQVMQYGSQSAN
                     MGNHIYKTIAEWIYFQTYHCTGKLETKDIRDYFPYPREDIQRFLHHNPPRPFC"
                     /name="YkgJ family cysteine cluster protein"
     gene            42227..42493
                     /locus_tag="HTV72_RS00290"
     CDS             42227..42493
                     /locus_tag="HTV72_RS00290"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032072053.1"
                     /translation="MISIAFASYILLALVVHLTLKQASYNGKVSSPAVNHACQQTSFLQ
                     PVWPLIFASNITRSMPALGVKLPAKKIAAIKGVVYIICIVRYR"
                     /name="hypothetical protein"
     gene            42510..42689
                     /locus_tag="HTV72_RS00295"
     CDS             42510..42689
                     /locus_tag="HTV72_RS00295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023408316.1"
                     /translation="MTEKITDEELVDLLEALKRAHGMGVCSKAVKLAQRCADVFPAIVA
                     ELQEYRNAAKRTSA"
                     /name="hypothetical protein"
     ARG             5852..6660
                     /name="blaNDM-5"
                     /gene="blaNDM-5"
                     /gene_name="subclass B1 metallo-beta-lactamase NDM-5"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(15450..16321)
                     /name="IncX3"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          21511..22667
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          25309..27458
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="90.098"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          28521..29572
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          29771..30495
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.21e-145"
     Typing          30505..31430
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.706"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          33878..35673
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="95.159"
                     /coverage="98.0"
                     /evalue="0.0"
ORIGIN
        1 actggaactg ttccaggggc aatttgcttt gagctggttt gatcgcttcc ctgtccaggt
       61 cgaacaacaa aaagatatga ccgccgtaat agagcaatgg cgcgaaacgc ttgctctggc
      121 gcatcaaaat gctgaggccg ggattgatat agaagcggtg ctttctatgg ctctgctgcc
      181 gtcagtgtca ccgcagaacg ggagccattc agatgatatg gccgggagca atgacaatga
      241 tttgtcagtt gcagcatttg aggacaagcc aaaacgaaat aaagttaaat atcagtgtcg
      301 cgggtgtggc gctgccgtgt ggggcaaagc cggactgaat attgaatgcg gcgattgcga
      361 gctggctttc atcgaaaatt aattgccagc aaattttccc ggtcacatct gttggccagt
      421 gttttttgcc agcaaagttt cttcccgggt tcgcgccggc agcgcaaaaa tgacagcaaa
      481 agaggggtat catggggcat tacacaatca gaacgaatga cgacgaagat caggccatta
      541 aaaaggcgca ggaagcgacc ggacaggcat cagccagcaa aacctttatg acggctatcc
      601 ttgagcttca gcgtaacaga gacgagatgg cgcagctacg gcgtgaactg gcgcaggaaa
      661 aagcgcggag tcaggagctg gtatcatcgg taaaacaatt ccgttccagc ctgaacaatc
      721 tgtttgatct ggctgacaac ccttaaataa caaggagcga aacgtgcata ccacaaatgc
      781 gattatcctg tgcctggtgt catatccctg catcgttgca tgggttatct ataaaaacag
      841 atttgtcgat tacttgtttt taactctgct tgcttgtttg gggagcattt tttcagtcgt
      901 attgtataaa cagcccgact actcattgac catatatcag gccgttgctg tcggctatgc
      961 tgccgtgatc atgccaacgg tgttagtttt gagtgtcgtt aatatcttca tgggaaaagc
     1021 agagagaacg tgcaaatgaa tacactggct gcactggaaa atacgtttcg tgatatgaga
     1081 aagcatggct gccaaacagt catggtcacg cagtctttag ctgattttgg ccgctacagc
     1141 tataaaccgc gccctgcatt tcaggactgg atcgaacggc tgaagactgg cgaacgtctg
     1201 ccgcgaggcc gttactttgt tggcaagaag cctggtggcc gcctggtgct cattgatgaa
     1261 ttggggggaa catggacaga aaaagtaaca gtgattcata ccaacgctgg atgatagaga
     1321 aggctgacaa aagggaaagg acgcaaatca gtatgtcgtt cgtaaagatg aaggacgtac
     1381 tttttaacgt gctggctatc ggtactgttt tagcagccct ggtggtgatc ttttatgaag
     1441 tgcaaagcag cttataaatt gatggccgtt gacaatgaat gtcatactac ctgaccgggc
     1501 aatgccggaa gatttctttc acgggtgatg gtttgtgatc ccggcattgt tccggcgctc
     1561 tctcgtaaat tctcgcgccc aatccccctc gcaaaacctc agaattcacg taacgcaccg
     1621 cgatttcggc aaccatcaac cctaacgtcc ttatgttgtt gggtttgccg cagaacaatt
     1681 tattcattta aaatagattt aaacgaagcg ggaaaccgca gacgtaaaaa aaccgactgg
     1741 tgaggtcggc ttttttacgg ttccggtgcg agctggtaac tcagcccgga agggaaactc
     1801 tctacaactg acaatagtat gataatccgt gaagcctgat tatgcaatat gacgggcagt
     1861 gactgtgcgt taacggtttg cctgaacgtt agataaacgt ataatcagag ggttagctct
     1921 gtggtgagtc tctccctgca ttccgctaaa tgcggcatga acaggttcaa agtcctgaca
     1981 ggtaatacag gtggtgctgg ttatctgtgc tctggcagga gtgagactct ctacaactga
     2041 caagacgaag agaagccgtg gtgacaggca gtgtaagagc aagccacggt gtctttactc
     2101 catttatgga gaaaacggat gattaacctg ttaatcatcg ttctgagggc ggtagcggcg
     2161 cttgcaaacg cgctgattgc cattctggaa ctgatccgcc agttcatcga ctaatgaaca
     2221 cggaaacgta attaaggccg gaggaacacc acctccggcc tttaataaaa atatagttta
     2281 gttacaacat tcactagtct gtactaacca ccacacacct gaccttctgc gcacaagtta
     2341 cctttaatca ctcctaaaca ggcatttcat gaaactcccc tgttcttgca tcggtaacca
     2401 acgttttctg cctctgacgc ctcttttaat ggtctcagat gtcctttggt caccagttct
     2461 gccagcgtga aggaataatg gccgagcata ttgatatgtc cgtggcaaag cggggagagg
     2521 cgtgcgatat cttcatcatt cagtgtttca ccctgcgccc ggagatgatc cagggctgcc
     2581 tgcatataaa tagtgttcca taacacgacg gcgttagtga ccagccccag tgtgcccagt
     2641 tgatcttcct gaccgtcggt atatcgtttt cttatctcac ctttttgacc gtgacagatg
     2701 gctctggcaa cggcatggcg actttctccc cgattaagct gggtcagaat gcgccggcgg
     2761 taatcttcat catcaatata attaagcaga tacagcgttt tgttgatgcg ccccacttca
     2821 atgattgcct gagtcagtcc ggaaggacgt tcacttttca gcaatgaacg gaccagcact
     2881 gaaacctgta ctttgcccag cttcagggag ccagcggtcc ggatcatttc gtcccactga
     2941 ggggttctag ggattttccg tccaaaaacg acaaagtgct ctggaggccc cgccgtctgt
     3001 ggcctccaga ggggtattac ttttttcgag atccctattt gggctctgtt tgagtaagat
     3061 ttagtctttt tgggctaaat ccatggcatt cgaagaacgt gtccaaatct tgtccgaggc
     3121 agaacaagat gagttatatg gaccccccgc tttcacctcc gccgaccaac gcttcttttt
     3181 ctcgctgaac gataaggaac tggcgatcgc taaaagcctc cgtcatcggg gccagcgtta
     3241 catgctggtg gtactgctgg gctatttcaa agccaagccg gtggtgctga atcccggctt
     3301 tcatcagatc aagcaggacc tcaaatacgt ttatcaaacc gttctaccag gcccaggctg
     3361 tagacccttt aatctcacgc caaaagagaa cgaacggatt taccaacgtg ttttccagct
     3421 ctgcaactac cagcgctgga atgtcaaaga ccatggagcg gcgttgagag attacttatc
     3481 ccagcaagcc agagcctgga cagcgcctag gcacctcttc gatgcggcca atgaatattg
     3541 ttcggggcag aagatcgcaa tccctgccta cagcacgctg caaaagatca tcagtcaggt
     3601 ggtgggagac gaacaggaac acatggccgc gcaccttgag cgtgcaatgt cacgcggtct
     3661 taagcaagca ctggcggagc tcgtgaacgg cacaggtcca ctgccgttcc gacagttgcg
     3721 acaatcggct cgtaacttca ccggaaccga gttggagaaa gaactgattg tctatcgcca
     3781 tatccagcat tggatgccgg aagtggatct gctgttgagc acgctatcac tgtcgcagaa
     3841 aaatctgcaa cacctggcag agaaagtcga ctactacggt gccaaactga aacgtcaaac
     3901 cgtaggcagc caatggctgt atttattgtg ctatcttcaa acgcgatggc agcaagcgct
     3961 ggaacgtatt gccgatggct ttgtgcatca tgtcagacag accaaacaga aggcaaagga
     4021 ttatgcgcag gaagcggtgt ttaaggattg gcaaaaagca gctaaaaatg tcagcaaggc
     4081 agctgaagta ctgcacctgt tcattgatga cagcattgat ctgcaactac cgtttgcaac
     4141 agtaagacag caagcactga gcctgctgac caaaagggat ctggaatctg tatgtctctt
     4201 cctgaacgag cagcgacgat cggtcgatga agccatgtgg cagtactgcg acgagaaaga
     4261 aagtctgcgg aaaggtttgc tgcgagagtt gttcctatgt ctgcgcttcg aaggctgcga
     4321 cggcacccag cacttagcgg ccgccttggc gaaaacacaa aacgaactca acggccagga
     4381 cgctcagttg caaactgccg acaccagact cctttccaaa aaatcacgtg aattcctgct
     4441 ggatggtgaa gggaatatcc tgatcgatcg ttatgagtgg ttcctctatg gaaggtgcga
     4501 ataagcgggg aaattcttct cggctgactc agtcatttca tttcttcatg tttgagccga
     4561 ttttttctcc cgtaaatgcc ttgaatcagc ctatttagac cgtttcttcg ccatttaagg
     4621 cgttatcccc agtttttagt gagatctctc ccactgacgt atcatttggt ccgcccgaaa
     4681 caggttggcc agcgtgaata acatcgccag ttggttatcg tttttcagca accccttgta
     4741 tctggctttc acgaagccga actgtcgctt gatgatgcga aatgggtgct ccaccttggc
     4801 ccggatgctg gctttcatgt attcgatgtt gatggccgtt ttgttcttgc gtggatgctg
     4861 tttcaaggtt cttaccttgc cggggcgctc ggcgatcagc cagtccacat ccacctcggc
     4921 cagctcctcg cgctgtggcg ccccttggta gccggcatcg gctgagacaa attgctcctc
     4981 tccatgcagc agattaccca gctgattgag gtcatgctcg ttggccgcgg tggtgactag
     5041 gctgtgggtc aggccactct tggcatcgac accaatgtgg gccttcatgc caaagtgcca
     5101 ttgattgcct ttcttggtct gatgcatctc cggatcgcgt tgctgctctt tgttcttggt
     5161 cgagctgggt gcctcaatga tggtggcatc gaccaaggtg ccttgagtca tcatgacgcc
     5221 tgcttcggcc agccagcgat tgatggtctt gaacaattgg cgggccagtt gatgctgctc
     5281 cagcaggtgg cggaaattca tgatggtggt gcggtcaggc aaggcgctat ccagggataa
     5341 ccgggcaaac agacgcatgg aggcgatttc gtacagagca tcttccatcg cgccatcgct
     5401 caggttgtac caatgctgca tgcagtgaat gcgtagcatg gtttccagcg gataaggtcg
     5461 ccggccatta ccagccttgg ggtaaaacgg ctcgatgact tccaccatgt tttgccatgg
     5521 cagaatctgc tccatgcggg acaagaaaat ctcttttctg gtctgacggc gcttactgct
     5581 gaattcactg tcggcgaagg taagttgatg actcatgatg aaccctgttc catggctcca
     5641 gatgacaaac atgatctcat atcagggact tgttcgcacc ttccttagag aaatttgctc
     5701 agcttgttga ttatcatatg gcttttgaaa ctgtcgcacc tcatgtttga attcgcccca
     5761 tatttttgct acagtgaacc aaattaagat catctattta ctaggcctcg catttgcggg
     5821 gtttttaatg ctgaataaaa ggaaaacttg atggaattgc ccaatattat gcacccggtc
     5881 gcgaagctga gcaccgcatt agccgctgca ttgatgctga gcgggtgcat gcccggtgaa
     5941 atccgcccga cgattggcca gcaaatggaa actggcgacc aacggtttgg cgatctggtt
     6001 ttccgccagc tcgcaccgaa tgtctggcag cacacttcct atctcgacat gccgggtttc
     6061 ggggcagtcg cttccaacgg tttgatcgtc agggatggcg gccgcgtgct gttggtcgat
     6121 accgcctgga ccgatgacca gaccgcccag atcctcaact ggatcaagca ggagatcaac
     6181 ctgccggtcg cgctggcggt ggtgactcac gcgcatcagg acaagatggg cggtatggac
     6241 gcgctgcatg cggcggggat tgcgacttat gccaatgcgt tgtcgaacca gcttgccccg
     6301 caagaggggc tggttgcggc gcaacacagc ctgactttcg ccgccaatgg ctgggtcgaa
     6361 ccagcaaccg cgcccaactt tggcccgctc aaggtatttt accccggccc cggccacacc
     6421 agtgacaata tcaccgttgg gatcgacggc accgacatcg cttttggtgg ctgcctgatc
     6481 aaggacagca aggccaagtc gctcggcaat ctcggtgatg ccgacactga gcactacgcc
     6541 gcgtcagcgc gcgcgtttgg tgcggcgttc cccaaggcca gcatgatcgt gatgagccat
     6601 tccgcccccg atagccgcgc cgcaatcact catacggccc gcatggccga caagctgcgc
     6661 tgagccatgg ctgaccacgt cacccccaat ctgccatcgc gcgatttcga tgtgacagag
     6721 gcgttttatg cgaagctggg ctttgcgacg agttggaagg atcgcggctg gatgatcctg
     6781 cagcgcggcg gtttgcagct cgaattcttc ccctatcctg acctcgaccc agctacgagc
     6841 tcgttcggct gttgcctgcg gttggatgat ctcgatgcca tggtggcatt ggtgaacgcg
     6901 gcgggagccg aggaaaaaag caccggctgg ccgcgcttca aagctccgca actggaggcg
     6961 agcggcctga ggatcggcta cctgatcgat cccgactgca cgctggtgcg gctgatccag
     7021 aaccccgact gaccgcatgc ccgcgaaaat caagatttgc gggatcagca cacccgaggc
     7081 gctcgatgcg accatcgcgg cgcgggcgga ctatgccggg ttggtgttct atccagcgtc
     7141 gccccgtgcg gttacgtcga atgtcgcggg cgctttgaca tcgcgcgcag ctggccagat
     7201 cgccatggtc ggtttgttcg tcgatgcgga tgatgctgtc atcgccgacg cactggtggc
     7261 agccaagctg aacgcgctgc agctgcacgg ttcggaatcg cccgaacgcg tggcccagtt
     7321 gcgcgcgcgg tttggcaagc cggtgtggaa ggcgctgccc gtcgccagcg ccagcgatgt
     7381 cgcacgcgcc gcagcctatg ccggggcggc ggacttgatc ttgttcgacg ccaagacccc
     7441 caaaggcgcg ctgcccggcg gcatggggtt ggcgttcgac tggtcgctgc tggccggata
     7501 tcgcggtgcc ttgccgtggg ggctggcagg cgggctaaat ccgacgaatg ttgccgaggc
     7561 gattgcgcgc accggagcgc cgctggtcga tacctccagc ggcgtcgaaa gcgcgccggg
     7621 cgtcaaggat accgacaaga ttaccaattt cgcctttgcg gtgcgcttgg cctaaatcgc
     7681 gtcgatcaat aggcgtcgtt cagcgcaaag atcggcttgc gggtgcgcca ctgccctcgg
     7741 gtgaagtcgg gaaaatctaa cgtgcgattg ccctcagcaa tcgattgttc cgacagaggc
     7801 gtgatcgcgc tccaggccag cgcgtcgtaa atgtcgattg gcatcggggc cttggccttc
     7861 agcgcctcga caaaagcgtg gatcacgaac cagtccatcc cgccatgccc ggcccctgcc
     7921 gccagatcgg cgtagcgttt ccatagcggg tgatcgtatt tcgcaaacca gccctcggca
     7981 ggctcccagc ggtgcggctg tgggctcttg ccctccagat agatcgactt gttgacgtcc
     8041 atccacagcc cctcggtgcc ttgcacccga aagccgagag aataggggcg cggcagcgag
     8101 gtgtcgtggc acagcatgat cgtttcacca ttagtgcagc cgatcatggt gttgaccaca
     8161 tcacccagtg cgaatttcac ctcggcgttg ggatgatcgg cagagccgtt cttgacgaca
     8221 taatcatgca gcccgcgcgc cttacagccg aagccgccag cgcccgcttc gcccggcaac
     8281 gcgaccttca gggtgcgggt ctgcggcggg tagcacacgc cggcatcggc gcagccctgg
     8341 tacttcacgg tcagggtggt cgcgctcgcg ccggccgcgg gcgtgccggt gagggtgccg
     8401 agcaattcct tgcggtaggt ttcgacgtcg ccgaagaatt cgtcgcggta ggccttgccc
     8461 ttcggcagcg ccatggtcgc gccggtgaag gcggcatcgg ccttgaccga ggtgcggtgc
     8521 cggtacaggt aatagccgtc ggcgatccgc cagcgcacct cgatgcggtc cggcgcggtg
     8581 gcctgcgcgg acaggacgaa gacctcgtcg accggcggca gttcgaagtc ctgggcgacg
     8641 gccgaggtcg cgggcagcgc aagcagcagg gcgagcccgg ccagccagcg gcgcaggcgg
     8701 atcgtggatg cggtcattgg ctcagtttac cggtcggctc tcggcggcca gccattgcag
     8761 gtattcgggc aggccggacg cggcttcgac cgcgagcagc tccgggagtt cgtagggatg
     8821 cagttggcgc aggcgttcct gcagggcggg ggtgcaggag atgctggctg aacgcggagt
     8881 gaatgtcgat cactccacga tttaccgctg ggttcagcgt tatgcgcctg aaatggaaaa
     8941 acggctgcgc tggtactggc gtaacccttc cgatctttgc ccgtggcaca tggatgaaac
     9001 ctacgtgaag gtcaatggcc gctgggcgta tctgtaccgg gccgtcgaca gccggggccg
     9061 cactgtcgat ttttatatct cctcccgtcg taacagcaaa gctgcatacc ggtttctggg
     9121 taaaatcctc aacaacgtga agaagtggca gatcccgcga ttcatcaaca cggataaagc
     9181 gcccgcctat ggtcgcgcgc ttgctctgct caaacgcgaa ggccggtgcc cgtctgacgt
     9241 tgaacaccga cagattaagt accggaacaa cgtgattgaa tgcgatcatg gcaaactgaa
     9301 acggataatc ggcgccacgc tgggatttaa atccatgaag acggcttacg ccaccatcaa
     9361 aggtattgag gtgatgcgtg cactacgcaa aggccaggcc tcagcatttt attatggtga
     9421 tcccctgggc gaaatgcgcc tggtaagcag agtttttgaa atgtaaggcc tttgaataag
     9481 acaaaaggct gcctcatcgc taactttgca acagtgccac aatgtgcgta atgacccccc
     9541 tgacctccaa cccgtcctca tcgtcatcag gtatagccct gaagttatcc agcttatcga
     9601 gttcctggag acaccgcttg gggtgtagtc gcaatcgcat gatcctgaat tcttgttcca
     9661 ggacacagag caccaaagac ccgtcaacgg gcgtgccccc aaaatctact atgagcagcg
     9721 caccaggctt tatcccttcc cggaaagagt aggtatcact tcgaaaaaag aatactcccg
     9781 gcgctcctgt attacagtgc tgatcgagtg acagcctgtt ttcctggtag tcggttgctg
     9841 gcgatggaaa acccattttt aacggcctcc gttggggtta aaaagcatga atgtccggtt
     9901 ctctccttcc tgagtggaaa tgtctttaaa aacggtcacg taggtttcaa tccactgatt
     9961 tgcttggcga caactccagt gaaaattaat cagcgcaagc tggctgacaa aggcttctgt
    10021 cgtaactgtc tgacgaccgt tcggctcacg cttaatgctc gcacgccagg ctgagtcaat
    10081 ttcatagtgt ctaggcatga aaaacctccg atcaatatag ctgtatgcat atgggtcttc
    10141 ccttgttgtg gtggctgaag gcatgataat ggtgtattta atcgccagag gtcaccgcca
    10201 tggacgaaaa gtccctctac gctcatattc tcaacctgtc cgatccgtgg caggtaaagt
    10261 ccctttctct cgatgaaaat gccggttctg ttactgtcac tattgagatc gctgaaaaca
    10321 cccggctagc ctgtccgacc tgcggtaaat cctgttctgt tcacgatcac cgtcatcgta
    10381 aatggcgcca tcttgatacc tgccagttca ccactattgt tgaagccgat gttccacgaa
    10441 ttatgtgtcc ggagcatggc tgcctgacgt tgcctgttcc gtgggctggc cccggaagcc
    10501 ggtatacgtt gctattcgaa tcgttcgttc tctcatggct gaaaatcagc accgttgatg
    10561 ctgtcaggaa gcaacttaag ctcagttgga atgcggttga cggcattatg acccgggcag
    10621 ttaagcgagg tcttgcccgg ataaaaaagc cattatccgc ccgtcatatg aatgtggatg
    10681 aggtcgcctt taaaaaagga catcgttaca taacggtgat ctccgatcgc gatggtcggg
    10741 cgctggcctt aacggatgat cgcggcacag agagtcttgc cggctatctt cgcacgctca
    10801 ctgatgggca gttgctggct atcaaaacgc tctcaatgga catgaacgcg ggctatataa
    10861 gagcagcgcg tatccactta cccagtgcgg ttgagaaaat cgcctttgac cgcttccatg
    10921 tggcgaagca actgggcgag gtagttgata aaacccgtca gaatgaacat ccgcacctcc
    10981 ctgttgaaag ccgacaccag gcaaaaggaa cccgcttcct gtggcagtac agcgataagt
    11041 ggatgaccga atcccggcag gaaaagctga tgtggctgcg tgcacagatg aagctgacga
    11101 gccagtgctg ggcgctgaaa gagctggcaa aggatatctg gaacaggcca tggagcgagg
    11161 aaagacggag tgactggcag agatggttgg cgctggcggc taacagtgac gttcccatga
    11221 tgaaaaatgc cgcgaaaacg ataggaaaaa ggctgtacgg gatcctgaat gcgatgcgac
    11281 acagtgtctc aaacggaaat gcggaggcac ttaacagcaa gatcaggctg ctgaggataa
    11341 aagccagggg ataccgaaac cgggagcgct ttaaactggg ggtgatgttc cactacggaa
    11401 agctgaatat ggcgttctga gccttcccac catgatcggg gaagacccat gcatatacag
    11461 tataaagaat cagttttatt cttcaacaca ctgtttatta tgttgtaact actccctacc
    11521 ttcaggttca tggttcattt tgttaacggt ctgttgcttc acagctttgc tgatagtcgc
    11581 ccggctacaa cccagcactt tttgaatctg gctccaggag ctgccgctcg caatcagcct
    11641 gtttatggcg tcatagcgag actgattaac ctggcggcct ttatacttcc cttccctttt
    11701 cgccctggcg atcccctgct gctgccgttc ccggcgctgt tcatagtctc gcctggcgac
    11761 ggcggccagc atatccagca acatatcgtt tatggccgaa aacattcggc tgtcaaaatc
    11821 attgtgaccc gatgcgagcc aggttgtcgg aacgttgacg gccacaaccc ggatatcttt
    11881 ctgccggatc attttcttca gtgtgttcca gtcctcccct accaggcgtg aaagcctgtc
    11941 cacatcctct accagcaaga tatcgttttg ctgacaatct ttcaggagcc ggaacaactc
    12001 agggcgttca agcttagaac ctgattcatt ttcaatgtag tagttacaga tgctcaggcc
    12061 gcgctcgatg gcgaaggtat ttatcgtgtc cagggcgcgt gttgcatcct gttcagtcgt
    12121 ggatgcgcgt aagtaagctc tgacaaagcc tttcggtact gtttgagtca ttatagggaa
    12181 ccagttcatt ttgagttaac cagacacacc catacagtac ccatttcagt tggttcaggg
    12241 aaggcacact caaaaagaac cagcaaacag accccagccc tatagtgaca acgtcacact
    12301 aaaaatttac aacataaaga tgatgtaaag acacaccaag atttacacca taaagcgcac
    12361 ataaagacac agcaacattt accatgtaaa gacaccataa agataaatat atctttattt
    12421 gtgctttaca tggtaaagcc attgcattat aaagacactg taaagacaaa agtatcttta
    12481 cgaaaaacac accatgtaaa gacattcata tctttacatg agctttacaa cataaagaga
    12541 gggattctga aatgggtaaa atcttgcttg tcgtatcaga taaaggtggg gtaggcaaaa
    12601 gcacctacgt ggctaacaca ggctcaatgc tggtcaacaa aggtaagtcg gtaattatcc
    12661 tgaagacaga taaaaaccac gatctgttga gctggaacga aaagcggaca gataacggct
    12721 tactcactat cccggttcac gcagcttacg gaaacgtcag caacgaaatt aagcgcctta
    12781 gtaagctgtg tgaagttctc attgtcgatt gccccggcca cgacagccag gagttccgta
    12841 gcgccctgac agtatcagat atcgtggtga cactggttaa gccgtcctct gatttcgaaa
    12901 gcgaaacact gaccagtgtt acagagaaaa tccgcaccgc tcagaaagct aacgcagctc
    12961 tggaaccgtg ggtgctgttc accagaatca actcagcgaa accccgccac agaaaagcgg
    13021 ccattgatct ggataaatta ctgcgttcgg acaacatctg gattcaacct ctgaaaaccc
    13081 ggatatccga gctggatgtg tatgaaagcg cctgtaatga aggggcaggg gtacatgacg
    13141 ttagccgggc atcgagcctt tcaacagcga aagcacagat tgaacttgtg gcacaggaaa
    13201 ttggcatttt atagaaatat caacaatatt catcgaaatc tttacattgt aaatacacca
    13261 taaagatact atgatattta caattaatgc ataccgtaca aggggaaatt ttcatggctt
    13321 taaaactaaa ccgcccgaac atcgatgaat ctcagcaacc agcaacaaac gcagaaaccg
    13381 cgcgttttat ctccggcgct accagagcgc ctgtagcggg taaaccaaag ttgatgaact
    13441 tcagactgcc agcgtacttt gaggagatcc tggaagcgga ggcgcagaga acaggccaga
    13501 gcaagacaac cgttctaaag gcagcgctgg ccgcattcga taacctggac gagaacctga
    13561 aaaaccactg gctgcttgaa tctgcaaaat tagggtagcg ttatggctaa gaaaaagaga
    13621 tatgttgtga tggttagaga taaaccaaat acagcggcaa tcagcgatta ttagcctggt
    13681 tagtatggtt cgctaacagg cataataagg ccgttgccta tgactgcgga gaatggattg
    13741 tcgaaccatc acattggtta agaattggaa atccaaaata gaaagaaacc taaggaaaga
    13801 aaaatgttca tattcagata tattaaaact cttattaata tctacttgtt atacatccaa
    13861 ccgatattgg ggatgttcct tataggtata ggcttatggg ggttctatgc acctgatgag
    13921 ggaacttgta ctaatctcaa tattgagtta tgcgctgtat cagctattga tgttctgaag
    13981 cctgctattt ttgtattttt aggcattatt accgttgccg gatggtactt taccgaactt
    14041 cagccgaagc taagggggga gggcaagtat atgaaggtaa aaacaggtgt aaaaccggaa
    14101 gatttcgtta agtaaaaacc gagcctaaag acgttaaccg tgggggattt atgaataaat
    14161 catggcttga acaacaggtg caaaatgaaa aattaaaaaa agtacaggaa gagaaaaaag
    14221 atggcactat ccaaaaagga ttgtacaggg ttcgtataaa agacaaatac aggtgggatt
    14281 tgtgggaaaa tgatttcaga gttgttattg cttattcgaa agatgatgca gagctaaaat
    14341 ttacagaaat gacaggtttt aatgagcatt actatataga aagcattgaa aaaatagtgc
    14401 tttcagatat agaaaaaatc ttactggaaa actgaaaaga tagttatcca gaggtttagt
    14461 taaataatgg cgtcagtttt tcaaccagta gcagatcgct taaaccgtct aaagaaacaa
    14521 cttctatacc agaatcaaca agtgaatcaa ctccacatac ttcaccgaag ccgataacca
    14581 taatcggctt tcggtctatc aaatcaaaaa tcaccaaagg caatattaca ctgttaatcg
    14641 cttcaaactc ctgaaaaaac atttcagagc cgtattcgct ggcaggaaaa agaatctcac
    14701 ttaatctcaa accataaaaa atatggtagt gttctttaag gttatccttt aaaatattaa
    14761 cagccttaga atatttttcg ttaataaact ctttaacctg atatttcata actctctcca
    14821 acaagaaccg actgtaggtc accgggcaaa cgttgcggaa tggcgtcaga gacgtcattt
    14881 tgcggcgttt gccctatcct gcatcgcagt gaaaagaact cgcctcgtgc gctatgatta
    14941 accgatgata aaaggctgaa agaagcactg caagccgact ggataacatt gttgcttcac
    15001 ggctgatcat cattggttgc ctcagtgcta gtgtgctttg catcaggaac cagaagacga
    15061 taccacggca tttttttgtt aagcagctcc atcaggggag tggcaaacaa actcaatccc
    15121 cacagcgtta cgattactgg aatcgtgaaa ttttgcggcg tccagaactg gcgctcaagg
    15181 tggaaccatg taacaacaca gagcattcca ccaatccaga aaatagcttt actgaaagcc
    15241 cccaggactg ccagagaaat aacagagact aaatgcagtg cgccagccgt agcaagacgt
    15301 agataaaacc agaaccattt agcgtgccgg ataaccgggt taccgttcgt ttctcgcaat
    15361 cgttttttac gttcccggat gatttctttt ttcagcttac ttcgttcggc tccctgcgga
    15421 aactcatata ttttagccat gttttgcctc acttattctt ttttggtgga acgactttgt
    15481 caaactcctc taaaaatgcc atatcatctt ccgaaaagga tgaggatttt tcatttatac
    15541 taaactcaaa tctaagcatg tgagccattc tccctttttt cccaacaaca gagaaagata
    15601 actgatttat ttccgttttc tcaattatct cattaatgct tttattgata acatcacgaa
    15661 caaaaaatga gtatttagga tacttatatt tcttctcccc ttcctcaata gtataaagtc
    15721 ccatttcctc ttttaaatca tccacggata tatcaaaaga tttttttgaa ctattctgac
    15781 tgtaatattt cctaatgact tgataaaggt ttgttgagtt tacactgttc aacaacacaa
    15841 ctgatttcaa tacctgagtg gtatatctat tttcagaacc aatcaactta gaaaaatatc
    15901 gcttagctgt atttgtgaat tttatccgta cagttgcaag atgatcgtaa taggcacaga
    15961 attctgttaa gtttaaatcc aagcgatcag gtattttatt cttagatgat agtatcccaa
    16021 gttcatcagc caaatttttt aaatcatctc tgtttaaaac taacgtagtt gaagaaagaa
    16081 ctttagctcc ctctttcaga gctgcataag aggcatattt atctaaagaa gtagcttttg
    16141 aaaaaaagtc agcatcaacc tccaaaatat catcatctaa catttccttt gtatcaatct
    16201 ggcaaagagc cagaaaaagc actctttttg ctgaaaggga aagggatgca agagttaccc
    16261 caacttcatt tctatgtcta actttcgtta atcccgttac tgtcttcacg ataagcctca
    16321 tataaccttt cctatgtagg caaatcataa ccccacaaag gttgtaattc aagacaacaa
    16381 tacaaccttt aattaaaaaa cctctcacct ttagatatga agatctgagg atcttcatat
    16441 ctaaagatag caacaaccgc atgtttcact tgatgttcag tcaaactgtg gaaaccgtta
    16501 aaaatcttct caccttacgt gaaaaatcct ctcatcttta gtgaaaaatc taactacctt
    16561 aacttaaaaa tcttctcacc ttacgtgaaa aatcctctca ccttacgtga aaaatcctct
    16621 cacctttagc aatttttttc cataattttc aggtaattga agcgagctaa gtttttaagt
    16681 ttttaagatc aagaagaaaa tataaggctt ttaatgcaca gcgtctgtgg ataactcagc
    16741 ataaatccag aggatagatc cgtctggcct ccctgagcac tgcaccacca aaaattgagc
    16801 aaatattaac cttagcgcgt aagtgctcta ttgaaacccc gtggaaattc cggtgtaatc
    16861 tctctaaaag atccagacgg gatccttttc cgatccaatt cttaaatgct ctcaaaagcc
    16921 ctcagaggcg ttttaaccgc tttaacccgg tcatggttca acggagcggg taaaatgcgc
    16981 ttagaacgtc atacagctcg tttttaacct gatccctaat cagggggtat aacagaggcg
    17041 gccaaaaaat ccggccttgc tcgtcagagt atctaccgcg cattatcccc gaacggaaac
    17101 ccgaccatca caacacttgc acagcttgca gcagtagccg ggttacagtt cactctcagt
    17161 aagcccaacc actaaccttt cagacaagcc cctcataccg gggggattat ttcttacgcc
    17221 agcaaaattt cacgaccggc gaggatggcc aagtgttttt tgctggcaat tttcgtgcag
    17281 cagctggcgc ccggattcat tttttgctgt caggcatcaa tcggtttcag caacccgccc
    17341 cgtaattcgc tgctaacgca tctcataacg cgcagataca gcgccccgcg ccagtgtttc
    17401 acactgaccc ggcgtaccgt tcgcaagctc acgcgctaac tgcgacaggc taaacatcgt
    17461 ctgatagtca gaaattggcc tggcaggggt gaggggggtt atcgctctca ttcgggcttg
    17521 ttggttcgcc agtcctggcg aacgtctccg gcgcgatgtt acgacagcgc attatgtaac
    17581 tacagttcgc gcctctttcg gaaatccctt catgcgcggt aaagcaatat acatctttat
    17641 gtaatcttta caatgtaaag cattaaaaat gattccataa ccatcatttg atggtataat
    17701 gaatttgttg gttgggaatg gttccctgcc agattccaga agcccacacg ggcgggagcg
    17761 aaaaatgaat attcaggaag cattaaacgt ttttggttta tccggtgatc tgactgaaaa
    17821 ggacatcaag gcggcataca aaaaagcggc tttaaaatat catccagacc gcaatccatt
    17881 gggtgccgag ctgatgaaag cagtaaatgc tgcgtttgat tttctcatgg ctaacattga
    17941 taaaatcaat cagtttcaaa gcactgatga aaacgcacgt tacaactacg gtgaagatct
    18001 ggaaaaagtt ctgaatacgc tttccggcct tacagggatt gtctatgaag ttattggtaa
    18061 ttgggtctgg attagcggag aaactaaaga acacaaagac attttaaagg aaatgggctg
    18121 taagtgggca tctaagaaaa aacaatggtt ttaccgtcct gaagaacaca aaagccgctg
    18181 gaaccgtaaa gaacacagca ttgaagaaat tcgtgaaatg tatggtacag cgggtaaacg
    18241 taaggcgtca ggctggacac gtgtagaagc aagcgcataa ccggaatggg ggcgaaagcc
    18301 ccctagaaca tggcaaagat tgattcggag acacgttgat gaaaaacaag accataacgg
    18361 aagcggagct gataaacatt tttgaaagtt acggagccta catttgcccg gatgagatcg
    18421 aagttacagc caaagaatgc aatgaaaatg gttcagtctt gcaccgtggc ttaaacgcag
    18481 aaggatgggc gcatcttttt gcgaaggaag aagcatatca gcaggaatgc gaagcccagg
    18541 aagctgcaag tgatgatgga cactttgatg aatagtctta aaactgccgt aattcgattt
    18601 acggcttttt tattgagttc aaaaggctga atcgatgaaa gaacagaaaa atttctttga
    18661 acggtataaa ccggtgtttg aaatcgtttg tcgaatcctg gggaacggct ggcgtgtaaa
    18721 tctgctcgat gattgccagt acaggattaa gctaacctca cctgatttta aaaattactc
    18781 tatacatatt cgaatggaga aaggaaggtt agttatcatt ggaagcgtag atagtcgcag
    18841 ctggagaagt ccttaccata cttgcacagt atcgccagag cgtaaccctg tagaaatcgc
    18901 cgccgatatt gaaaagaaaa tcctgtcgga tgctttagat aatgtagata tggcgcgaga
    18961 gtatgaacaa cagttacagc aaaaacgcga gaaaaaactg atcctgaaag gaatgctatc
    19021 tcgtttagtg catcttgaaa gctggcatgg gacattgacc gggtttaaag ttgagaatgg
    19081 gttagatggt aacgtatcag aacggggcga cggatatgaa atggtaattc gtggcctgag
    19141 tgtagatcag ctcataaagg tagcggggtt tattaaacag ctatgaggca aaaaatgaat
    19201 gaagtcctga gcgacaggaa aaacaaaggt aatgtaacat acaggattgt tgtgtctgaa
    19261 gatgcaacac gtttgtttat tgaacttgaa aaactgatga aggtacgctc taaagaagcg
    19321 gataaaaaaa caactaaaaa gattgttttc caaaaatcat tttattacga agaattctcg
    19381 aacgttaaag atgaaattga tgatccaatt ttattgaaat tctatacaga tactattgtg
    19441 aaggtacaaa atcatgagtt ttaagccaac acctgaagag gtgaaacaag cacgtattaa
    19501 agctggcttt acgcagcagg aagccgctga acggtttggt tttacgttat cagcctggca
    19561 agccaaagaa acatccggta aaacgtctcg tggtttagcc gctggtacgt atgaattact
    19621 tttgctcctg gctgatgaac atccagatta ccagctcgtt aagagagaaa aaaatcagga
    19681 taaagtgact aaataaattg cattaccatc atatgatggt ataatttatt tgtaggtcgg
    19741 gaatagttcc ttaccatgat ccagtagccc aaacgggcgg gagactaaaa tgaacacgta
    19801 tgttatcact ttccaggctt taaacactaa gaaagaaaaa atcacctgct ctgcttttgt
    19861 ccattcagaa actctcttcc ttgccgttca ttctttcgaa gataaaaatc gcggtcgtgg
    19921 ttatgttatc acgtctgtta gtgaattgtt gtccgaggaa ctgacggcga aaaattccct
    19981 caagaaaaat attaactttt ggtttaatga gtgtggttta agtaaatctg aggttataaa
    20041 cgaagtaatt aactggaaga atttcgcata tacccttaaa gaactggagg aagccaaaaa
    20101 tgaagcgata agagaactgc ggagttaatc aattaggggt ggtatcaggt tgtggaggca
    20161 acctgatacc gtgacactca attccctcgc gaggaatata aaatgtcgga acgcatgtta
    20221 tcagcaatac agactgttga aaagggtggg cgtccggttt ttcccttgat gccattctct
    20281 gcttttcctg agtacatggc attactcaga aaagccctgg aaaagaaaga aacaaaagca
    20341 ctgatagaaa aacaggaggt gctatgaaaa aacaggagtt tttagatttt atcagtgcag
    20401 aacagaggcg gggagctgtc cggttttcgc tgggatttaa cagcaaaggg gaaattgtat
    20461 tgcactggac taacgaggcc gggttaagag tctggagtat actaagcggt aacaggggaa
    20521 aaagtcccag ccgggcaaac cgggaaagaa tgagtaacct ccgccgctgg ctccatgatg
    20581 cccggcaggg catggaaggc gacacaccag aggcagaata aaattcccgt tcctgaatcg
    20641 ccgaagccct cccgtttacg ggaggtgctt tttttgtata ttccgtaaaa cagcgctcgc
    20701 gccccctgcc aggccattcg cgtagcgaat ttatttccgc ccaagttagc cgcgaatccg
    20761 ttgtctccgg tcgcagacgc accagatcac agccacgata gcctttcatt ttttgcattt
    20821 cgatggacgc tgaagcacaa tttatgtgtg gaggtagttc actgcgatgc aggatagggc
    20881 aaacgccgca aaatgacgtc tcttacgcca ttccgcaacg tttgcccggt gacctacagt
    20941 cggttcttgt tggagagttt tatgaaaaaa gttcaattca ggattgaaga aagccaacat
    21001 gatgatctac ttgattgtct taaaacactt tatccagatg aaccgggttt aaccgtggca
    21061 aaaggaatga agctgcttgc caatgcttta ctgaaaagca aggttaaaaa tgaagatgtt
    21121 aatgtgtcaa aagacaatga tgattttatc aaaaccacaa tgtatttgac agggaaacaa
    21181 agaactttaa tagagaaagc ggctcatcgt catggctgga atttatccag agaatgtcgt
    21241 tatcgaatcc agacgacact tgaaaatgaa cttgattttt tcgatcagga acttctggtg
    21301 atgaatcgtt gccgtaatgc aatagataaa atagggcgaa actttcatta tattatcgtt
    21361 aatgataatg ccagagtact tgataaagat gggttctatc aggacgctga gcggttgagt
    21421 tcagagataa tgagtctcaa aagtgagttt gaaaactaca ttatgttatg caaagggcga
    21481 actgtttcta acaaggttga ggtgtaatca tgggcgttta tgttgacaag gaattcaggg
    21541 ttaagcgtaa gtcctctgaa gctggccgca agtctgcttt cgcccataaa gttaaaaatg
    21601 gtggtaaaaa ctatcaacgc aacgttcagg aacgtatcaa ccgcaagggt gccagtaagg
    21661 aggttgttgt caaaatctca ggaggtgcga ttacccggca gggagttcga aacagtattg
    21721 actatatgag ccgggagtca gagctgccag tgatgagtga aagcggtcag gtatggaaag
    21781 gtgatgagat tcaggaggct aaagagcaca tgatagatcg tgctaatgac cctcaaaatg
    21841 ttttcgatga taaaggtaag gaaaataaaa aagtaaccca aaatattgtg ttttcaccgc
    21901 ctgtatcagc aaaggtaaaa cctgaagatc tgcttgagtc tgtcaggaaa acgatgaaca
    21961 agaagtaccc aaatcatcgt tttgtgcttg gctatcataa cgacaaaaaa gaacatccac
    22021 acgtgcatgt cgtttttcgt attcgtgata atgacggtaa acgagctgat atcaggaaaa
    22081 aagatttacg ggaaattcgt acaggttttt gtgaagagct gaagatgaag ggctatgacg
    22141 ttaaagccac tcataagcag cagcatggac ttaaccagtc tattaaagat gcgcacaaaa
    22201 cagcgccaaa acgacagaag ggcgtttatg aggttgttga tgttggctac gaccattatc
    22261 agaacgataa aaccaaacca aagcagcatt tcataaagct taagacactg aacaagggcg
    22321 tggagaaaac atattggggg gctgattttg gtgagttaac cactcgcgag aacgttaaga
    22381 aaggtgatct tgttaagctg aagaagttag gacaaaagga ggtgaaaatc cctgcacttg
    22441 ataagaacgg tgtacagcat ggctggaaga ctgcacacag gaatgagtgg cagctagaga
    22501 acctgggggt taagggcata gacagaatct cttcatccag taaagagctg gtgctgaaca
    22561 gcgcggagat gattaagaaa cagcaactcc agatgagaaa tttctcgcaa ataaaacagt
    22621 cgatgattca aagcgaacag aaagtgaaaa tcggaattcg tttaggataa ttcatactct
    22681 ccggtaactt attgattaag atcgatttat ttatcttgtt agcagagttt ttgtaaaaag
    22741 taactagcgg taaaaaattt agttaacttg actataaaat aagcgcatgg tgatcaatcg
    22801 atctgctttt ttgttatcaa atagcatatg tatctagata taaataaaat acaagcacaa
    22861 acaaaatgaa atgtgtcgta aatgcgatct aaagatctgc ttgtgtggtt gaacgcagca
    22921 catgtagctg ataaagtttt tatgagatgt aaatttgtcc ttttgttttt tttctctgat
    22981 tcggggtcat ccgagtcgag agagcgcctg aaaggaaaaa ctatggaatg gtatgttttg
    23041 caattcacca ctacgagatt tgcagcagtt tttgctcatc tcgaacgcct gaacttctct
    23101 tacttctgtc ctatggagac tgaaaggtat cgtcgcccgg ataagataat ttcatatcga
    23161 gaaagacgtt tgccgctttt tcccggttat ctttttatcc aggcagattt tgaagaggtt
    23221 cattccacta caataactgc tatcccttac gtacaacgct ttatctcatt tggcggtgag
    23281 cctttacctg taccagaaga tgtgatggcg gagcttttgt acagacaatc acatacaaca
    23341 gctcaggcaa atcttttaag gaaatcaatt ccacacgatt ttgctgaaat tctactcatg
    23401 gataatccgc agcaaagaag tatggctttc atccactaca tcacagagag aagcttaacc
    23461 cacaaaatga aacggaagaa aaatgactgc tacccgaaaa aaaaccgcaa cgagacgcaa
    23521 gccccaacgt aatacactct acctgccctc agcttctcgt gaggaactgg ataaaattgc
    23581 tctggagatt ggctatcgca gggggcgacg tatttcaagc tctggtgttg tccagtacct
    23641 cataaaaaaa tattccagcc aggctattga ggagctgata aacgaagacg atgaagacga
    23701 tgacgacttc gatgactaac cattcagtct aaactttccg cgctgttctg gccgggagaa
    23761 aatcatgtta tctactactg cttttgcggc gcttgctttg caatgcgcgg ccagcgttca
    23821 tcccgatact gcgcatgaag ttgcaagggt tgaatctggt tttaacccat atgctattgc
    23881 cgagataata ccgaaggttg aacgtaagcc cggtgacaaa ggcgtagtgt cctactttcc
    23941 caaaactaag gaggctgcac tccagatcgt aaatcaaatt gaatcacgaa atcatcgtta
    24001 ctcagtcggt cttatgcaaa taacgagtac gaattttgca aacttcaata caaccgctga
    24061 gaaaatgttt gacccctgcg aaaatctcaa ggtttcagag caaattttgg tggattgtta
    24121 taaacgtggt ggcgatattt tacgtggcct gagttgctat tattccggca atccagaaac
    24181 aggaactaaa cctgaatcag attttaataa caccagttat atacagcgca tagggtttaa
    24241 tccgcctgat aacaaaaaaa actgggtggt tccttcagtt aaagatgcaa tcagaaagga
    24301 gaatgtaaca cagagtatca aacctaaaga agttaccgta tatccccaat atgccatgcg
    24361 tggcactgtt ttagatgaaa aggaaacaaa cgatgttaaa actcaataaa cgttatttaa
    24421 ctctttctgt atttatggct gcattgatgc tttgtgtagc agaacccgcc tttgctgatg
    24481 atgtatccac taaaacaact ggcttcttgc agaagattat cgattttctg acggatatcc
    24541 gtaagccagc aatcaccatc attgcgctgg taattggtta tatcgctatc ttctcacgcc
    24601 agcatgcagc gtggattacg cctttaatta tcgggattat catctttatt gttgcgccat
    24661 atctgcctga ctggttagcg taatatgtaa taaaaggggg cgtaaaaatg agtaccgttt
    24721 ttaaagggct gacacgcccc gctttgatta gggggctggg cgttccgctc tacccctttc
    24781 ttggaatgtg cgttatctgc gttttgcttg gtgtctggat tcatgaggct atgtatgccc
    24841 tcatcctccc tggctggtat gccatcaagc gagttacgaa gatagatgaa cgcttttttg
    24901 acctgcttta tctgcgaatg caaatcaaag gtaatcctct ggcaaacaag cgcttcaatg
    24961 ccgtccatta tgcggggagt tcgtacgacg cagtcgatat atcgaaagtg gacaatttta
    25021 tgaagcttaa agaccagtct tctcttgaag agttaatccc gtattcatca cacatcactg
    25081 ataacctcat tgttaccaga aaccatgatc tactggcgac ctggcagatt gacggagctt
    25141 attttgaatg tgtagatgaa gcggatctag ccttgcttac tgaccagctc aatacgctga
    25201 tacgtagttt tgatgggaaa cccgttacct tttatacgca tcgtattcgg gttagaaaag
    25261 aagtgcgacc tgtatttgac agcaagatcc cattcgtcaa cagagtgatg aacgattatt
    25321 acgaatcgct ttcggcggct gagtattttg aaaacaaatt atacttaacc gtatgctata
    25381 aaccgttcag cgctgaagat aaagtgacgc attttctttc aaggaaaaag ggtaataaaa
    25441 atatcttcga agaacccatt aatgatatga atgaaatatg tggcagattg agcacctatc
    25501 tctcccggtt tcattcccgt cgtcttgggt tatatgaaga aaataatata gtttattcag
    25561 aacagcttac gctgttccag aaactgctat ccgggcgctg gcagaaagtc agagtcacca
    25621 atagtccgtt ttatacatac ctgggtggta aagacctgtt ctttggtaac gatgctggac
    25681 aaatcactgc ctctgaccat gcccggtact ttcgttgcat cgagatcaag gactactttc
    25741 aggaaacgga tgccggaatt tttgatgcac tgatgtatct cccggttgag tatgtacaga
    25801 cttcctcttt aactccgata gacaagcagt ctgcaatcaa ggcgctggat gatcagatcg
    25861 acaaactcga aatgaccgat gatgccgcta aatccttgct cgctgatttg aaagttggtc
    25921 tcgatatggt ctccagcggc tatatttctt tcgggaaaag tcaccagaca ctgattgttt
    25981 acgcagattc gccggagcgt ctggtgaagg acaccaatat tgtaacgacg accctggagg
    26041 atttagggct gatcgtaacc tattcaacct tgagtcttgg cgcagcgtat tttgctcagt
    26101 tacctggtaa ctacacgtta cggccacgcc tgagttctat cagcagtctg aactttgccg
    26161 aaatggaaag cttccataat ttctttacgg gcaaggagaa aggaaatacc tggggtaaca
    26221 accttatcac cctgggcggc tcaggaaatg atatttataa cctgaactat cacatgacta
    26281 ccgagcatca aaattacttc ggtaaaaacc ccacgctggg gcataccgaa attcttggta
    26341 cgtcaaacgt gggtaaaacg gtagtgatga tgactaaggc tttcgccgcc cagcagttcg
    26401 gaacgccgga gtcttttcca cctgagagga aattaaagaa gttaactaca gtatttttcg
    26461 acaaagatcg ggcagcggaa cccggtatac gttcaatggg aggtgcttac tttcgggtga
    26521 aagaaggaga gccgactggc tggaaccctg cggctttgcc accaaccaaa cgaaatattt
    26581 cctttatgaa agacctggtg aggctacttt gtacgcttaa cagtgagccg cttgatgatt
    26641 accagaaccg cctgatttct gatgccgttg agcgcctgat gcagaggtca aaccgctctt
    26701 atccgatcag taagttgcga ccactcattc tggagcctga tgatactgaa acccggcggc
    26761 atgggcttaa agcacgcctg aatgcctggg tgcagggagg ggaatttggc tgggtgtttg
    26821 ataacccgga cgatacgttt gatgtggaca acctggacgt tttcggtata gacggaacgg
    26881 agtttctgga taacaaagta ctttccagcg ccgcttcatt ctatctcatc taccgtgtca
    26941 ccatgctggc tgatggccgc cgactcctta tctacatgga tgagttctgg caatggatta
    27001 acaacgaagc gttcagagat tttgtttata acaaactcaa aaccgcgcgt aagctggata
    27061 tggtgcttgt cgtagcgaca caatcgccgg atgaactaat taaatcacct atcgcggctg
    27121 ccgttcgtga gcagtgcgca acacatattt atctggcgaa ccccaaagcg aaacgtagtg
    27181 agtacgtaga cgagttggaa gtgagagaac tttattttga caaaattaaa gccattgacc
    27241 cgttatctcg tcagttcctg gtcgtcaaaa acccacagag gaagggggaa agtgatgatt
    27301 ttgcggcttt cgcaagactg gatttgggaa aagcggcgta ttacctaccg gttctcagcg
    27361 catcgaaacc ccagcttgaa ctgttcgatg aaatctggaa agagggtatg aagccggaag
    27421 agtggcttga tacctatctg gaacgtgcaa acctgattta aggaatccct atgaaaaagc
    27481 atatcgttgc ggcacttatc gcctctgtta cggttatttc tggtgctcag gctggtgttc
    27541 ccgttgccat tgatgcaaac cctgaatggg ctgtcgaagc gcagcgctgg acagaacgcc
    27601 tcaaacagtg gcaggacacc gtgaaccact accagaaaca gattaatgcc tataagcagg
    27661 agctgctgac caaaacgggc attcgtgatg ttcagggact ggtgcagtct gcgcaatctg
    27721 tcagtaagga gctggagaat atttacgacc aggggaactc cttcattgat gattacatta
    27781 agaacccgga agccaccctg tctgagcaag ccagatcact actggccgat tataaggtga
    27841 caaacacctg taaggggctg ggatatacgg gcgacctggt gcggggctgt gaagcctcgt
    27901 tcctgtccca actggcgggg atcgagtacg gcaataagct ggaaagtaaa ctgcgtgaag
    27961 ataatcagga aatggccgac cttatcgacc aggtgaagaa cgcccaggac acgaaagcca
    28021 cgcaggacgc gacaaacgct gtatctctgg caagcctgaa atttaacaag ctcaaatttc
    28081 agtatgaaat gtatcgcgat aagcagcgcg atcttgcaga atacaaggag aaaatgttac
    28141 aggctgcttt ccaggagaaa caattagggg ctgttaataa agaaactcca gttgttgatt
    28201 ataaggcagc atttgagcag cagagttatg aaatgaactg agggggcatt ttgaaaaaat
    28261 atggattagt tgcggcgttg gggcttacat tctttcttac cgggtgtgaa gaggttaaat
    28321 ctgtagactg gtggcagtct cacgtagacg atgcaacgaa aaaagtagct gaatgcaaaa
    28381 agtctgggag tgatagcgaa aattgtaaaa acgctaagga aggtttgttt aggtataagc
    28441 aattacatcc taagcatgtt gactataaag atgcattcaa aaatgtattg ggtaaagatg
    28501 gaagttaaaa ggagccacta tggcaacttc taggtatttc caggccgctc atgacgttat
    28561 tgttaaaact cttgaccagt ctttgactgg tcagttagat aacttttctt caatagcgtc
    28621 tcagttgggt aagtatggta tttccattta tatattgtgg tatgcttata ccacaatagt
    28681 tgggaagcaa aaaaccgcag tgcaggattt tttatggaat ctatgtcgat tctggttaat
    28741 tcttgttttt gtcaaaaata tgggggggtg gttagatagt gcaactcagg ccattgatgg
    28801 gctgaaggaa acatttgcag gaggtgatcc ttggaaatgg gttgacgagc tttgggagaa
    28861 agttcagcag gtagctgcat atcttatgtc caaagatact tcgaagtatg tgaaaacaga
    28921 tggggcaatc gcatctttat taacatatgc tggagggata attgcattat tgctaacttc
    28981 aatagtttat ctcgccgccg aagttactat taagatactt actattaccg cgccgttgtt
    29041 tattatttgt ctttcatttg gttttttaag gcagatgttt aatagctggc ttcagttaat
    29101 atttagctca tgcttcatat tcttgttttg tggactggca attaaagcgg gaatgacgtt
    29161 ccttaatggc attctgacaa tctcgatagc taacgcagat gaattaaatc tgatatcaac
    29221 aggtgctcag gccggggttg caggtgcatt tatggcctgg attatctggc aagccaaaac
    29281 ctatgcttcc cagctcgcag gggtaggtgt tgaaggcgcg atgcaagggg cagccgcaat
    29341 ggggattggt gctggcgtgt tcggcgcttc ccgtatgggg cgtaatctgc ttggtatggg
    29401 taaaaatgca gggattggcg catggaaagg cgttcgccgt caggatggag ggttcaacca
    29461 gtctcctggt gtatccggta agttggggaa tctgaccggg cagggcgtta atattggcgc
    29521 taagaggctt cgccaggctg cgatagatgc ggcgaaaaag aaatatggag gttaaccgat
    29581 ttattattta aatctgtcaa ctctgagtat tccgcagtaa atattcactc ctctatttag
    29641 gttctcacat tatgaaacta cttatcacgg ctatcgtgac gctttgcctt gtcggatgcc
    29701 aggcgtcaca taaacaacct ccggtatccg gaaaaagcga acctgttaat tcagcagagg
    29761 taatgcgcaa tggggtttaa actctcagga ttaaaacttc ccggttttaa caagaaaaaa
    29821 gaagtaacag actcttcaac tacttttgaa gagaaaaatg tattgatgca ggagaaaatg
    29881 aaccgcattt ataaattcgg tggtattgca ggaattgccg taggtgtgtt gtctctgctg
    29941 gcactgaatg gagcgctacc gttaaagagt acggttgtcg aagcttatct tattaatggt
    30001 gtcactggcg ttgctgaaag actgacttct gttaaaaaag aaaacctctc tgaaaatgaa
    30061 gcgctggcga aatacttcat tactcagtat gtgaagcgtc gtgaagggta taactatttc
    30121 agtctccagc atgattatga ttatgttctg ttatacagcg ctgagaatgt ggcgacggat
    30181 tacaacgctt taatcaacgg caaccagtca ccaaaggtta tttataataa agcggaaaaa
    30241 accgcatctg ttcaggataa tccgtccgtg attatcagtc cgtcatcccg gcgcgatgat
    30301 aaggatatgg gagcatatat ccggtttaaa ttaaccattc gaaatgtcgc gacaggccag
    30361 gatgattatg aatactggaa cgtccggttg acctaccgta ttgaaccaca ggtcgaaatg
    30421 gcatcgggtg accgaaacaa taacccgctt aaattcgttg taacgagcta tgtacgcgat
    30481 aaagaagtga aagggtgaaa actatgaaaa tgaataaagg agcgctaatt gtggcgcttc
    30541 tgttggtgtc gcacgtctgc catgcagccg ttacgccagc agccagccgt tttgatcccc
    30601 gtaatcagat tgtcagttat aacccgcaaa acacgacagt cataaacagt gcggttggct
    30661 atacaaccac actggtattt gacgaggatg aaacggtcat cagtgccaga accggctttc
    30721 cccagggctg ggaagtgaac aaagaagata acctggtgta tctcgaagtg aagcccgtca
    30781 aacagaccgt acagaagaac agtaccgatg acaatggcaa ccagtcttca gaggtggtca
    30841 gtgtagccct tgatcctgaa aacgacctgg aacgctggcg aacaaacctg tttgttcgca
    30901 caacaaaacg taattacagc atggagctga acgcccgaac gttccggcag ccggataaga
    30961 tcgcgtttgt tgttaattac cagtacccgc aggaacgccg gaaggagcaa gccgaaatcg
    31021 agaagaaacg gattgaggct cttaacaagc ggcaggagga gcaggcaatc aaccgttctc
    31081 ttgaaaatgc gaagtcgccc aagaactggg attactggaa gcgggtagct gacggcagcc
    31141 agtcaatcag cccggattat gcgtatgacg atggccgcta tacctggttt ggcttcagcc
    31201 ccctgaagaa aatccccagc gtctttgtta tgagcggcga acaggaaacg ctgactaacc
    31261 cggtagtcaa aaacagcggt agtttcaccg ttgttggtgt tcctgtagac cagcgctttg
    31321 ttttgcgtat gggaaatcag gttgttgggg ttgaaaaccg gggctttggc aaagtccgtc
    31381 ttccggcagg agataccgtt tccccgaacg ttgagaaaga ggtgatccag tgagcgaaca
    31441 ggaaaataaa atcccgaccg ctgtagaaat tgaacaggca ctacgggaac ggcatcagaa
    31501 agaaattgag caaaacgata aaacggataa gggagatgaa gatgacggta aatcagtaaa
    31561 acgcctgggt atcgagaagc ttaaaaaatc gcgtaagggg ctggtgatta ttgtggccgc
    31621 tttccttctg ctggccgccg gggtgtctgt ctactatatc ccgtcgatta ttcgtgcaat
    31681 gtccagcggt gatgataagc ctgccagtaa tgcggtatct actggttcag taaaacgcgc
    31741 gacaggactc agcgatgatg ttgatccatt caacaccagg gaagaaccgg ctaagacgga
    31801 agaacggaag gaaagcagcg gcaaagcgga aacgccaccg gaaaaagtac aacaaaactt
    31861 cagtcgtgcg ctggatgtgg cctatggggg gagcagctct gcttcctcaa attccggtgg
    31921 tagctcatca acggccagca ataccaggaa cgagggggac ggcagtgaca aacaggcaga
    31981 ggttcagcct gttaatgcag ggcaacccgc gcagctttct aaaattacgc gcgttcctta
    32041 tgaccctaac cttttcattc ctgaaaatac cgcgattaag tgctcgctgg acagacgatt
    32101 tatttctgat ctggctggca agctggtctg tacgattaat gaggacgtat acagtgcaaa
    32161 caggaatgta aagctaattg aaaagggaac agccgcatat ctgatgtata aaacgggcac
    32221 gttcaatcat ggtcagggag ccgtgtttat cgctgctacg aagcttagaa cacgtaagga
    32281 acctttcatt gatattccgc tgattgatac acaggcggcg ggagcgctgg gtgaggccgg
    32341 ggcttcaggc tggattgaca cacattttgc agatcgcttt atgggcgcga tgatggttgg
    32401 catgatcccc gatgtggcac aggccgcaag tggagcggct aaaagtaata aagacaatca
    32461 gaccgactat acagctaaca gtcgccaggc ttttgctgat atagcacgcg aagcgtttgc
    32521 aaacagcgta aatatccctc caacgcttta taaaaaccag ggggaaatca ttactctgat
    32581 cgttggtcag gatttggatt tctccagcat ctacaaatta aaaatggtgg gtacccggag
    32641 gtaatttgat aacgctggat atcaaagagt tttcaatgct gttaggaata agggaaagcg
    32701 aaatatacca tcatattcgt aagggcatac caataaatgg cgttcctttc cccaaaccac
    32761 tgaaacaaat caaaacgcat cgatttaatt acgaagaagt catgcgtttt attgaagatc
    32821 ttaaaggaaa aggtgaatta tgaaggatgc agagaacaga catattgttt atgaaataat
    32881 agatgaatac ttccaccact ggcttaatga agtcgatggt ttaactgaaa tcgcggtaaa
    32941 tcggcctgat gaactgtttg ttaaagtgag tgggaaatgg cagcagcatg aattaaaaat
    33001 ggattttaaa gattgtatgt catttgcagg ggcaatttct gattatcatg atggtgggtc
    33061 ggttacgcca gaatatccct tacgttctgt tacgctcccc ggaggggagc gtgtacaaat
    33121 agttattccc ccggcaacgg aacgggaaac ggtgtctatt acaatccgta agccgtccag
    33181 tgtgtttatc gaccatgata cctttgttaa acaagggttt tactcaaggc taaatcaagg
    33241 ggggaaattc agggataaag aagatgaatt atcttcaatg tttaaagata attgttttga
    33301 acaatttgtc cctgaatgcc tggttaaggg taaaacgatg gtattttgtg ccggaacggg
    33361 ggcgggtaaa accacctttg caaatgcctg tcttcagtac ataccccatc atttacgatg
    33421 tatttcaatt gaagatacag atgaagcaaa gttcaggttc cacaaaaatc atgtgaaatt
    33481 gtattacccg tcagaagggg aaagtagcac tgtcagttcc gcttctcttt tacgttctgg
    33541 ttttcgtatg aacccggaca gaatcctcat gactgaggtt cgcggcgcgg aagcctggga
    33601 ttttctcaaa ggctcaagtt ccggccatgc agggaacctt acaaccgtcc atgagagcac
    33661 ccctgaagat gctgtgcttg gactggttca acggtgctat atgaaccctg aatgtcagaa
    33721 tttgccttat aacattatat tgcggagggt gttaagcaac gtcgatgtga ttatgagtat
    33781 taagtacatc gatgaggaag ataaccgatt tgcatcgggt atttactatc gtgatattca
    33841 ttttcaggaa tactttgaaa agctgaagga gtgattatgt ctctgaaact acccgataaa
    33901 ggccagtggg cttttatcgg tctggttatg tgtcttgtga cgtattatac tggctcagtt
    33961 gctgtttact tcctgaacgg aaaaacgccg ctttatatat ggaagaattt tgattccatg
    34021 ctgctgtggc ggataataac agagagtaat atacggacag atatcaggtt aaccgcaatc
    34081 ccctctcttt tatcaggtat ggtttcgtct ctcattgtgc ctgtttttat tatctggcaa
    34141 ctgaataaaa cggatgttgc tctttatggt gacgcgaagt ttgccagtga taatgattta
    34201 agaaaatcga aacttctgaa atgggagaaa gaaaacgata ctgatattct tgtaggtgca
    34261 tataaaggta aatacctgtg gtataccgca ccagattttg tatcacttgg cgcaggaacc
    34321 cgcgcaggta aaggggctgc aataggtatt ccaaacctgc tggtcaggaa acattccctg
    34381 attgcattag atccaaaaca ggaactgtgg aaaatcacca gtaaggtacg tgaaaaactg
    34441 ctgggtaata aggtctatct tcttgaccct ttcaacagta aaacgcatca gtttaacccg
    34501 cttttctata ttgatttaaa agaagagagc ggggctaaag acctgctgaa gctgattgag
    34561 atcctgttcc cgtcttacgg tctgaccgga gcggaagcac actttaataa cctcgcgggg
    34621 cagtactgga cggggctggc aaaattgctt catttcttta ttaactacga cccctcctgg
    34681 cttggtgagt tcgggcttaa acctgttttc tcaattggtt ctgtagtcga tttgtacagc
    34741 aacatcgacc gggagctgat actcagtaag cgagaagacc tggagggaac aaaaggactt
    34801 gatgaaaacg cgctgtatca tctgcgcgat gccctgacca aaatcaggga gtatcacgaa
    34861 accgaagacg aacaacgttc gagtattgat ggttcgtttc gtaagaaaat gagtctgttt
    34921 tatcttccga ctgttcgcaa atgtacagac ggcaatgatt tcgaccttcg ccagttgcgc
    34981 cgggaagata tcactgttta tgttggcgtt aatgctgaag atatgtccct ggcctatgac
    35041 ttcctcaacc tgttctttaa cttcgttgtg gaagtcacgt tacgagaaaa ccctgacttt
    35101 gacccgacac tgaaacatga ctgtctgatg ttcctggatg agtttccgtc tattggttac
    35161 atgccaatca ttaaaaaagg ttcgggttat attgccgggt ttaaactcaa acttctgacg
    35221 atttaccaga atatcagtca gcttaatgaa atctatggtg ttgaaggtgc caaaacgctg
    35281 atgagtgcgc atccctgccg gattatctac gctgtcagtg aagaagatga cgctaaaaag
    35341 atttcggaaa agctgggcta tatcaccacc aaatcgacag gttcaagcaa gacaagcgga
    35401 cgctcaacgt cgaaaagcag ttcagaaagt gaggcgcagc gcgcccttgt gctcccgcag
    35461 gagctgggaa cgctggattt taaagaagaa tttatcattc ttaaaggtga aaacccggtt
    35521 aaagctgaga aagccctcta cttcctcgac ccgtatttta tggacaggct gatgatggta
    35581 agccccaaac ttaccgagtt aaccgcctct ctgaataaga ctaaaaaagt attgggtgtt
    35641 aaagggctta aatatccttc taaagaaaaa atgctctccg tcggtgagct ggagtcagag
    35701 gttttactat gaaaaaaatg ttaatggtca gtgtcctttt tctctctgcc tgttcctctc
    35761 cgcctgaacc accacaggtt gactgggaac agaatcctga aacggtgaat acacaattaa
    35821 tggactggca accgacatac tcagttatta aatcagacaa ggttaattca tcgtgggtta
    35881 aggttatcca taatttcagg cctgaaaacc gcctttacga tgatgctgtt ttttattctg
    35941 ttgcacattc tgattcagtg attgttgaaa ccagtaacgg aacagacttt ttcacagcta
    36001 aaaactggtt gagggcgaac ggtgcaaacg gtgtcataca gtatcgttat aaaatgaact
    36061 gtttttcttg ccggactacc agtgtttatt tatcacgata acgccggatt aataaaattc
    36121 ttgtaatttt attgagccgg ggttgaacaa ccgcagggcg ttagttgccc gttatccatg
    36181 aggtgtatat gaaaaagacc gtaaccacgg cagtgctgct ttgtgcgttc gctgccggaa
    36241 ctgctcatgc tgaggaaaag gccgacccga acgatccatg tgcaatggtg ttatgccttg
    36301 ccggaaaact tgacggaagt agtccggcag aatgtgaccc gatgtataaa agttttatgt
    36361 caatcaggaa aaagaataaa catggttttt tacccgatca cacggcagat gccagaaaga
    36421 aaaaactaaa tgaatgtcct gcggctgatg caggtacagt aagtaaaatt atttcaagct
    36481 ttggccgatt gaaaaacttt taattctgtt tgatttaatt ctgatgtgaa tacgcaagtt
    36541 tcaggtttga gactggaact tgcgaacatt ttttacaggg gtgggaggat gaaaattatt
    36601 aacgtacctg atgcaagaag tgtgagaatt gccggaattg aaattatcga tagtgtcaaa
    36661 tcggtcgctt ctgtttttac tgaaattttg ttgtttatgg tctggtttcc ggcaattgtc
    36721 tatgggcttt atcgttttgt tatcgttttg tgggatgctt ccttaaagcc gcaatcgctc
    36781 attgagttta ttaatttcat ggttgagtta tacagctatg tacttccttc gttggctgtt
    36841 atcgcagtgg ctttagtcgt cgttttatcc atttttaaaa gactctcagc aatatgggag
    36901 ggaagaaagc aatgagacat ttttttaatg ttctttcctt tgctgttgcc ctgttgccag
    36961 ctacattgtg tgctgctcag attcagggga aagttattcg cgttctcgat ggagatacca
    37021 tcgaagttaa aacactaccc gcgaaaattg ttgtgtatga agttccgatt cgagtccgat
    37081 tgataaatat cgatgcaccg gaaaaaaaac aaccctttgg tcgctggtca accaatcaac
    37141 ttaaagccct gctggcaggg caatcagtta ccgtctctta tacgcaaaca gatcgctacg
    37201 ggcgagtcct gggacgagtg gtgacagcga acggcactga ggctaaccgc cagcaagtgc
    37261 taaaaggggc tgcatgggtt tatgacaggt acaacaccga taactcatta ccggctctgc
    37321 aacgggaagc tcagacacag aagcgcggcc tgtgggctga cagtaatccc gttcctccgt
    37381 gggagtggcg tcataaacaa aactgacgcg cttcgcttgt ccaacccctc ctctgcctga
    37441 agaaaatctt caggcaacgt cacggttttt aatatacatg gtgcgcatat gggtaaatta
    37501 actctggtag agcaggcttt acggctccat aaagaatatt acggtgaaga taattttggt
    37561 actgtcgtaa aggattgtga ttactatcct aaagtggcag agatttttat aaacagaaag
    37621 aatcgtaaaa tttattcgaa tcttgatatc gaacccgttg cttcaaccgt cgttcatacg
    37681 ggaagtagcc ctgttatggc taaagccggg aggattaaaa agcttatgtt taaagatggt
    37741 tcgggagcat accggattca tcttggtcaa aatgaagtgg ttcatattat tcgcttcatt
    37801 cttaactcta aagtcagaat ggagtacgca gttggcacaa ccaaaagtat gtcgatgctt
    37861 cataatcttt gcgaagctgg acgcgctaaa ttaaaccgct ctttaccccg taaaggtatc
    37921 tggaaaatcg ggtgttacga cggcgtttat tatcacggta aggcaaggaa ggaagaaata
    37981 gaaaacgctt tacgtttttc tgttcatcca aagtttaatg agctggagaa tgactttaat
    38041 cagttctttt cggatattga tttctacacc cgttatggtc agtcaggaat gcgaaaagtg
    38101 ctttttactg gtcctccggg cacagggaaa acgactatcg caaaagcttt gggggcaaaa
    38161 tatcaggata aatatgtatt tgtttatgct gatgattact ttaaagatgt ttgctatgcc
    38221 gcagctcaaa agaaaatacc cgttatcata atagctgaag aggttgatga actttatcgg
    38281 gctgatgccg gaacgttaag ttttcttgat ggggctgata caccgcgaaa tcttgccggg
    38341 acatatgtta ttttttcaac gaactatcct aaccggattg atccgcgcat cagaaaacgc
    38401 cctggcagaa ttgacagaat catatctgta ggtgcttttc ggactaaagc cgctgccgct
    38461 tgtgccaaaa tgtacttacc agacgatata aatattgacc ttaaagaact tggcgcggtg
    38521 ctggacagaa cgactcctgc tgaaataaag gagataataa atattgctat tggcatgatt
    38581 cgcggaacaa aaaacgaatt aacagtagat gtaatcaaga atgcgcgtgc ctttttgaaa
    38641 ggaacccttg accttagtgt gcaggaggca gaagaagaca tagaggaaag ggaagaaatc
    38701 tttaaaaaga atggtgcgca gcctgactat tcaagttacc ttgaggattg attaatgaga
    38761 ctttttattg cagaaaaacc gtctttagca aaggctattt ttgaaggact gggcggaaat
    38821 cccaatacag aaaagaaaaa cggctatttt gaacacggtt ctgatgtcgt tacctggtgt
    38881 tatggtcata tgctggagct ttacgaccca caggattatg acgacaaata ttccaactgg
    38941 cgttatagtg atttacccat taaagcggtt tatccgccaa aatataaaat caagcctgaa
    39001 tcagaagcac agacccgcat tattttgtct cttatcgata aagccgacag catcgttcat
    39061 tcaggcgacc ccgatgatga aggatgtttg ctggttgatg agattctggg ttatgccgga
    39121 aacaagaaac ccgtccagcg actgcttgtt gccgacctca accttgcgcc agtgcaaaaa
    39181 tcactgtcga atttacaacc taacgataaa tttcgcggta tgacgttaag cgccctggcg
    39241 cgttccctgt gcgatcaggg ttttggctat aacatgacgc ggggatgtac attaaaaggc
    39301 cgtgagaagg gctatgacgg cgttctgaac gttggccggg tacaaagtgc cgttcttggt
    39361 ctggtgaaca tgcgcacgct ggcgaaccag aatcacacag aaagctttta ttacgatgta
    39421 ttcgccagtc tgtcgatgaa cgggcatcag attaaggcga aatatcagac aacagacgac
    39481 gatcagatag acgagaaaaa acgcctgatc tccgaagctc aggccgcgca tattgccgga
    39541 cgtgttacgg gtaaggatgc tattgttact atcgcgacga caaagccgga aaatagcaag
    39601 cctccgcttc cgcttaacct ttccacgctt cagcagctct gcgcaaagcg atttggttat
    39661 tctgcaaaag atacgctcga tgtgatgcag gggctgtatg aaactcacaa gcttctgacc
    39721 tatccacgtt ctgacaatcg ctatctttca gatgagcatt attaccaggc cggagatatt
    39781 gccactgcta tagcggccac cgtacccgaa ctggcgtctg cgatcgtaga tatggataaa
    39841 ggccagaaac acaaagcctt taatgccagt aagattgagg cgcaccacgc catcatcccg
    39901 acgacaaaaa gcggagccgg tattcagctt aatgaaaaag agcggaacgt ttataacctg
    39961 gtgtccgtct actttatcgg gctgttctac ccggatgcga tccgcaacaa gacgaaaatc
    40021 cactttgata ttaaggggga tacctttacg gccacacaga gcgttctggt acaaaagggc
    40081 tgggaagcgc tgggtaagga tagtgatgac gaggacgaaa ccgaagatgc cggaacggac
    40141 ggttttgacc tttcattgct gaaatttaat gacagcggcc tgtgtgaatc ggcagacgtg
    40201 gacaagaaaa agactacacc acctcgctat ttcacagagt caacgttact ggccgccatg
    40261 acgagtgcgg caaaattcat tgatgatccg gctctcagaa aggcgctgga agcgaaagac
    40321 gagggcagca gtgatcgtgg cagtatcgga acggaagcca cccgcgcggg tattcttgag
    40381 aaactggcgg caaataccgg gcttatctcc atcgaaaaag aaaaggggta ttcggagctg
    40441 gtatggaaaa ccacaaaaca aggccaggag ttttgcgctg cactgcctcc tgaaatcact
    40501 aaaccggata tctccgctct gtgggctgaa aagcagtctc agatcaaagc cggagagctg
    40561 acagttgagg agtttattaa ggaaaatgat gagtacgtcc aggggttaat cgacgagctg
    40621 gacaggaacg gaatttcgat ttcttcaaat gccacgccct gcccggtttg taacaacggt
    40681 ttcctgcgta agcgtaaggg gcaaaatggc tttttctggg gatgctcctg ctaccctgaa
    40741 tgcaagacaa cattcccgga caaagacggc aaaccggata tggaagcaaa atccagatca
    40801 gaaggttcca tgtcccggct cgaagccccc tgcccttcat gcagtaaaga aattattatc
    40861 cggcctaaag gctttttctg ttccgggtgc gagtttaaaa tctggtctga agtgtcagga
    40921 aaaaaactga cacaaaatca ggttgagaca ttaatcaaaa aaggtaaaac cggagagatt
    40981 aaaggcttta ccagtaataa aaccgggaaa aagtttgacg ctgcaattgt tttgcaggat
    41041 aaaactacgg gtaaacttgg gtttcagttc agtaaaaaat aaggattaac tcgatgagtg
    41101 aaaatgaaac gtttgacgca acaaaaaagc tactcctgaa tattcgctct gttcgtgttt
    41161 ttgcgcgaga aaccagcttt gaacaactgc tggaaatgca ggaaaagctt aacgccgtga
    41221 tcgaagaacg tcgtgaagaa gcagagcgtg aggcagcaga acgcgcagag cgcgaaagaa
    41281 agcgccagga actgctccag ttgattgccg gagaaggttt ttcaccggaa gaactgcttg
    41341 gcctgtccga agatgcgcaa aaaacacgca aaaagacgtt gccaaaagcg ccgcctaaat
    41401 atcagtttga tgaaaacggc gaaacgaaat actggtctgg tcgtggccgg acaccaaaac
    41461 caatcgacga agcgttaaaa gctggccgtt ctcttgatga gtttctcatc aaaaaagatg
    41521 cttccagcac tgctggtgac gaacagtaat ctaacaagcc tctgacactg cgtcagaggc
    41581 ttttttttag caaaaagggc gcggggggtt atggtgaaga aatctttgga tatcttcgcg
    41641 gggataaggg aagtagtctc tgatatcttt ggtttctaac ttaccagtgc agtgatacgt
    41701 ctgaaaatag atccactctg ctattgtttt gtagatgtga tttcccatgt tcgcgctttg
    41761 agaaccatac tgcatgactt gtgcatccag gtcattacac atctccggcg gagtgagtac
    41821 atgatatgtc ctgcataaca gcgggcggta attgtagatt gagcatgttc ccttctcaga
    41881 caaaaacgga cattttgact catgcccggt cgtaagcggg ttgtctctgg cagtaagttt
    41941 acttgcttgt gcaatatgtg ttgcctcaag cgcggttaaa tgaacatcca ttttacagca
    42001 cgaagagcac cccttttgac aggaggtaaa cgtgctcaca aattctttgt taaaacgatc
    42061 caaaaaggcg tacatctgtt ttaacttgag gtaaatatta ccggattgag tattgagttt
    42121 atttatgagt gcctttaact catcgaaata cttatcaggt acgggtttca gattggtata
    42181 gccgggtaat gtttcgcctg gctccaggtg gatcactgag ttaggtttga tatccattgc
    42241 ttttgcttcc tatattcttc tcgcgctggt tgttcatttg acactaaaac aagcgtcata
    42301 caatggcaag gtgtcaagcc cagcagtaaa tcacgcttgc cagcaaacca gtttcctgca
    42361 gccggtttgg ccgttgattt ttgccagcaa tattacccgc tcgatgcccg ccctgggcgt
    42421 gaaattgcca gcaaaaaaga ttgccgctat caaaggtgtg gtttatatta tctgtatcgt
    42481 acgatacaga taatggagaa gcttaataga tgactgaaaa aatcactgac gaggaactgg
    42541 tagatttgtt ggaggcgctc aaaagagcac atggtatggg cgtttgttca aaggcggtta
    42601 agctggcaca gcgttgcgct gatgtgttcc ctgctattgt tgcagagtta caggaatatc
    42661 ggaacgccgc taagcgaact tcagcatgac aagagccacg gaacgcgctt acagcgagct
    42721 acaacaggcg tttgatttct ataaccagcg cctttttgac ggcgaactcc ctgactgtct
    42781 gattacgttc cagcgcggca agaacacaat gggctatttc agttacaggc gctttgttgc
    42841 tgctgacggc agcggcagga tgattgatga aatcgccctc aatcctgaat acttcccggt
    42901 gtacccgctt attgaagtca tgcaaacgct ggttcatgag cagtgccata tgtggcagta
    42961 ccactacggc aacccgtcgc gtaagacgta ccacaatgcg cagtgggcgg caaaaatgga
    43021 aagtatcgga cttatgccct cctccaccgg gagacctggt ggtgcgaaag tcggccagaa
    43081 gattaatgac tatccgatcc ctggtggccg cttccagcgc gtcac
//
