LOCUS       NZ_MH785258            17747 bp    DNA     circular CON 21-JUL-2023
DEFINITION  Staphylococcus aureus strain ph1 plasmid pPH1-2, complete sequence.
ACCESSION   NZ_MH785258
VERSION     NZ_MH785258.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN09846913
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 17747)
  AUTHORS   Bukowski,M., Piwowarczyk,R., Madry,A., Zagorski-Przybylo,R.,
            Hydzik,M. and Wladyka,B.
  TITLE     Prevalence of Antibiotic and Heavy Metal Resistance Determinants and
            Virulence-Related Genetic Elements in Plasmids of Staphylococcus
            aureus
  JOURNAL   Front Microbiol 10, 805 (2019)
  REMARK    DOI: 10.3389/fmicb.2019.00805
REFERENCE   2  (bases 1 to 17747)
  AUTHORS   Bukowski,M., Hydzik,M., Sabat,A.J. and Wladyka,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-AUG-2018) Faculty of Biochemistry, Biophysics and
            Biotechnology, Department of Analytical Biochemistry, Jagiellonian
            University, Gronostajowa 7, Krakow, malopolskie 30-387, Poland
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/21/2023 01:19:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 20
            CDSs (total)                      :: 20
            Genes (coding)                    :: 17
            CDSs (with protein)               :: 17
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 3
            CDSs (without protein)            :: 3
            Pseudo Genes (ambiguous residues) :: 0 of 3
            Pseudo Genes (frameshifted)       :: 1 of 3
            Pseudo Genes (incomplete)         :: 3 of 3
            Pseudo Genes (internal stop)      :: 0 of 3
            Pseudo Genes (multiple problems)  :: 1 of 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MH785258.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..17747
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ph1"
                     /isolation_source="tenosynovitis"
                     /host="Farmed pheasant"
                     /db_xref="taxon:1280"
                     /plasmid="pPH1-2"
                     /geo_loc_name="United Kingdom: Scotland"
     gene            complement(300..1295)
                     /locus_tag="D0Y80_RS00005"
                     /old_locus_tag="D0Y80_m00000"
     CDS             complement(300..1295)
                     /locus_tag="D0Y80_RS00005"
                     /old_locus_tag="D0Y80_m00000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157643.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="WP_000838599.1"
                     /translation="MKSLKSKAFIYGLLFTFIIAVISLLGSKLPFLDKIGALTIAILIA
                     ILYRHFKGYPEAYRSGIAFSSKRLLKLAIILYGLKLNIYDVIGKGSDLVLIDIGVILFS
                     IGLMLLLNKYIKGDKNLILLLGIGTGVCGAAAIAAVSPILKSREKDSAISIGIVALIGT
                     IFSLAYTVIYSIFTISPEVFGVWSGTSLHEIAHVILASDFSGQEALSMGLLGKLGRVFL
                     LIPLSIILILIMRKKSHSENEKKRIDVPYFLLGFVMMALFHTYVSLPHMVMQIIDNITT
                     ICLLMAMVALGLNVSFKDLKDRAFKPLIAVIIVSICLSTVTFIVAKYFYS"
                     /name="YeiH family protein"
     gene            1420..2241
                     /locus_tag="D0Y80_RS00010"
                     /old_locus_tag="D0Y80_m00005"
     CDS             1420..2241
                     /locus_tag="D0Y80_RS00010"
                     /old_locus_tag="D0Y80_m00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002477850.1"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_000377738.1"
                     /translation="MDSLKVLTEVVKTQSFTKAAENLYTSQPSISRDIKRLELEYDVKI
                     FEFRHSKMSLTSDGEKLFQYALQRERLEQNLRHDLKMQPDIISGDLTIGSSYTYGEYRL
                     SQHLADLAKNYPELYIHVYLNNSDTVLQHIKNNTIDLGIIEKEVQSNIIHSRRIAQDEI
                     VLIRKKSSSSNKSICFIRERGSGTRVYQENALSQMTSSSYLVEINNTNLIKNMVHADKG
                     FSIVSKSTLTPYDLEKLEVTNLDIKRYFYLVIHKDKYIDTKLNEVIKNLIS"
                     /name="LysR family transcriptional regulator"
     gene            complement(2543..2635)
                     /locus_tag="D0Y80_RS00015"
     CDS             complement(2543..2635)
                     /locus_tag="D0Y80_RS00015"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(2801..3148)
                     /locus_tag="D0Y80_RS00020"
                     /old_locus_tag="D0Y80_m00015"
     CDS             complement(2801..3148)
                     /locus_tag="D0Y80_RS00020"
                     /old_locus_tag="D0Y80_m00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(3167..3784)
                     /gene="cadD"
                     /locus_tag="D0Y80_RS00025"
                     /old_locus_tag="D0Y80_m00125"
     ARG             complement(3171..3784)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(4016..4234)
                     /locus_tag="D0Y80_RS00030"
                     /old_locus_tag="D0Y80_m00020"
     CDS             complement(4016..4234)
                     /locus_tag="D0Y80_RS00030"
                     /old_locus_tag="D0Y80_m00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000153199.1"
                     /translation="MTIKQIVNDLLNKKWSLEDLFWLILMCVIFSTFTTPFLGIPIGVI
                     AYFFFFYKDDDFDEIAEKYDYQDENKK"
                     /name="hypothetical protein"
     gene            complement(5104..>5393)
                     /locus_tag="D0Y80_RS00035"
                     /old_locus_tag="D0Y80_m00130"
                     /pseudo=""
     CDS             complement(5104..>5393)
                     /locus_tag="D0Y80_RS00035"
                     /old_locus_tag="D0Y80_m00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(5413..6387)
                     /locus_tag="D0Y80_RS00040"
                     /old_locus_tag="D0Y80_m00040"
     CDS             complement(5413..6387)
                     /locus_tag="D0Y80_RS00040"
                     /old_locus_tag="D0Y80_m00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_031885784.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNQFTHNFDDKEMLLQEFPEQLT
                     NYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHDRGV
                     KGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            6813..7556
                     /locus_tag="D0Y80_RS00045"
                     /old_locus_tag="D0Y80_m00050"
     CDS             6813..7556
                     /locus_tag="D0Y80_RS00045"
                     /old_locus_tag="D0Y80_m00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843733.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKREDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            <7728..>7856
                     /locus_tag="D0Y80_RS00100"
                     /pseudo=""
     CDS             <7728..>7856
                     /locus_tag="D0Y80_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335299.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            <7857..7973
                     /locus_tag="D0Y80_RS00105"
                     /pseudo=""
     CDS             <7857..7973
                     /locus_tag="D0Y80_RS00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            8142..10274
                     /locus_tag="D0Y80_RS00055"
                     /old_locus_tag="D0Y80_m00055"
     CDS             8142..10274
                     /locus_tag="D0Y80_RS00055"
                     /old_locus_tag="D0Y80_m00055"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773099.1"
                     /GO_function="GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity [Evidence
                     IEA]"
                     /GO_process="GO:0006306 - DNA methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="WP_012816642.1"
                     /translation="MKTTKQILKDFNISRQTLMNWINTKAITTPSKDWRGWYIWSEKNL
                     EELEKLMSDKREANIKVSKGNFDEELNIYNRRYLGSKKRLLSFIEEVVNKHTNNINTVA
                     DVFGGTGVVSDLFRNKGKKIIINDILKSNYVTYLTWFSNDPVDEDKIRRYIDYLNTLKP
                     IDNYVSDNFGDRYFSIDNAKKIGTIREAIEDLEDLNGREKAFLLTSLIYAMDKVANTVG
                     HYDAYRKTMDMTKELYLKMPVVNFNRDNDIYCKDANQLVKEISADLIYIDTPYNSRQYS
                     DAYHLLENIVEWKKPPVTGVAKKMVDRSKTKSNYSTNKAPEAFADLIKNIKARYILVSY
                     NNMARKGNGRSNAKISNEEIIHTLEKKGKVKVFETSFQAYTTGKSVIDDHKEILYLCEV
                     SQKEVKNKQKNHYTPSAINYTGSKYRLLDQIITLFPKEYNNFIDLFAGGSSVAINSNPK
                     NKILINDNIKPLISLYRYLSITDYDSVIKDINSLIDDYGLSRSSKYGYSHYHVDSSKGL
                     AKYNKEGYLRLRSDYNCGKFHGNALENIVLYLLTVFGFNNQIRFNKNGGYNLPVGKRDF
                     NDKMKEKLKQFMKALHEKDIIFSSDDFRDVIPLSNDTFLYADPPYSITSATYTENSSWS
                     AKDDADIFDYLDKCHENGIKFALSNVAQHKGTVNEELLKWAKKYNIHYLDFNYNNSNYQ
                     STAKSKITHEVLITNY"
                     /name="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
     gene            10324..12429
                     /locus_tag="D0Y80_RS00060"
                     /old_locus_tag="D0Y80_m00060"
     CDS             10324..12429
                     /locus_tag="D0Y80_RS00060"
                     /old_locus_tag="D0Y80_m00060"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF021040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="WP_172693172.1"
                     /translation="MLLLKLGDKNQILNFANTNGRRNDLINAYTIYMNILNESFESGIY
                     IWDRFPNSLGQFHFYSRALEESKDVFQQHGPYDYICKKLELPEYREAFHNMDKEKIIQL
                     EGGNDFIKKLDNGVEDRSRHYTSTLTKIGFIHEDRQLSSVGKLFISESDPVRNDFEKLL
                     PIDKINLLLLRQGLKIRVYTDDYQKYYSPIMLLLYILFKNEKVNAKDLFTLLNTITPYF
                     PFDYKEISDSFSKDNVRDVIQKYEKLFIAEPLVEGKRLEKEEFYKKFSNNKTSKDQHIY
                     FDFYNKLLDFVTDPADSTYSQLEELFEDKYKKNVLNNTFGQKKKFLEFNVSDYNEFIDV
                     NYDSNILSLDSFNSNFYIKFFNSKRNKDIHDYKDMLKRFTRATGIIEINNGVVNLAYRD
                     VWIEYFKYVDFDGLIFNTDTKNSAAEYEYSVDSVFYKDVTINKIFDITDEQMNDIIESI
                     KNKLSIDSVESIKKNLVNRNDILFKEFINSEFPLKKTMSILNMFSDRSNDKEIKKIVGS
                     EAGVPTIYEYMIGIAWYHISNKEYDVFSSFNLTMNANFLPETHAGGGAGDIVVKYNDNT
                     LMLEVTLMNKNAQKRGEWEPVLRHATNLTIDEHPKKVRTLFIADELDENTINIWRAVAS
                     VPMKSTTGKKDYAENLIIMPFTTAEIITLMNRNIDENKIFTSIDSSYSQLKSNFNSNWR
                     NDIINSF"
                     /name="AlwI family type II restriction endonuclease"
     gene            12629..13195
                     /locus_tag="D0Y80_RS00065"
                     /old_locus_tag="D0Y80_m00065"
     CDS             12629..13195
                     /locus_tag="D0Y80_RS00065"
                     /old_locus_tag="D0Y80_m00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655834.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_160203788.1"
                     /translation="MNIVEPIRDIQMIKQMKESLNYYGTKRDVFLFVLGINCGLRVSDM
                     LILKKGDIKDYQIRIKESKTKKHKVIPLHHIKNEIDEYIQFLEDDDFLFKSNRKDKHGN
                     QKAINRIRAYKILNEAAKNIGLENIGTHSMRKTFGYHYYKSTNDVALLMDIFNHSSQSV
                     TLRYIGINQDIMNASISNAMKGLYD"
                     /name="tyrosine-type recombinase/integrase"
     gene            13262..13936
                     /locus_tag="D0Y80_RS00070"
                     /old_locus_tag="D0Y80_m00070"
     CDS             13262..13936
                     /locus_tag="D0Y80_RS00070"
                     /old_locus_tag="D0Y80_m00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISSau6 family transposase"
                     /protein_id="WP_001105942.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGIYVHHS
                     TIYRWVQEYAPILYQIWKKKNKQAYYKWHIDETYIKIKGQWNYLYRAIDADGHTLDISL
                     RKKRDNHSAYTFIKRLIKQFGKPQMIITDQAPSTKVAMSKVIKDFKLTPNCHCTSKYLN
                     NLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRSLQIYGFSPCRVISIML
                     AS"
                     /name="IS6-like element ISSau6 family transposase"
     gene            14537..14851
                     /locus_tag="D0Y80_RS00075"
                     /old_locus_tag="D0Y80_m00085"
     CDS             14537..14851
                     /locus_tag="D0Y80_RS00075"
                     /old_locus_tag="D0Y80_m00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633163.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_012816638.1"
                     /translation="MNEVIGNPLLDKFMKDLIIQILAMISEQERNESKRRQAQGIQVAK
                     EKGIYKGRPVLYSPNAKDPQKRLVYYRVVELLEQGKSISTIAKEVGITRQTIYRIKNSK
                     "
                     /name="recombinase family protein"
     gene            14912..15226
                     /gene="arsR"
                     /locus_tag="D0Y80_RS00080"
                     /old_locus_tag="D0Y80_m00090"
     ARG             14913..15223
                     /name="arsR"
                     /gene="arsR"
                     /gene_name="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     gene            15223..16515
                     /gene="arsB"
                     /locus_tag="D0Y80_RS00085"
                     /old_locus_tag="D0Y80_m00095"
     ARG             15227..16512
                     /name="arsB"
                     /gene="arsB"
                     /gene_name="arsenite efflux transporter membrane subunit
                     ArsB"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16533..16928
                     /locus_tag="D0Y80_RS00090"
                     /old_locus_tag="D0Y80_m00100"
     CDS             16533..16928
                     /locus_tag="D0Y80_RS00090"
                     /old_locus_tag="D0Y80_m00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent arsenate reductase"
                     /protein_id="WP_000358995.1"
                     /translation="MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVN
                     PKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFD
                     DPAGKEWSEFQRVRDEIKLAIEKFKLR"
                     /name="thioredoxin-dependent arsenate reductase"
     gene            complement(17119..17727)
                     /locus_tag="D0Y80_RS00095"
                     /old_locus_tag="D0Y80_m00120"
     CDS             complement(17119..17727)
                     /locus_tag="D0Y80_RS00095"
                     /old_locus_tag="D0Y80_m00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_012816637.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPI
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNLL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGQAISKIAKEVNITRQTVYRIKHDNGLS"
                     /name="recombinase family protein"
     ARG             16534..16925
                     /name="arsC"
                     /gene="arsC"
                     /gene_name="thioredoxin-dependent arsenate reductase"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(4901..5048)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(5107..5282)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(5414..6387)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.59"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6814..7556
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aatatacacc ctaatcatac gttttaatcg cgataaattc aacaactttt ttgtatgatt
       61 agggtgtacc ctaaattata ttgttccata gttaatagaa atattgaaat ttactataat
      121 taaactgtca aggtaagtcg gaatatgcat tgtaaagctt gatatgtcag taataataaa
      181 gaagaatagg cctagtaaga aaaaggctga tctttttttg accgtagtaa tatggaatgc
      241 cttcaatgtg ttgtgtttgt ttgtgagaat ctatatcaat tttttaatat acttatagtc
      301 taactataaa agtacttagc aacaataaat gtcacagttg ataaacaaat agatacaata
      361 atgacagcta ttaatggttt gaaagcacga tcttttaagt ctttaaatga aacatttaac
      421 cctaatgcaa ccattgccat caataagcat atagtagtga tattatctat aatttgcata
      481 accatgtgtg gcaaggatac ataagtatgg aataatgcca tcatgacaaa accaagtaaa
      541 aagtaaggta catcaatacg ctttttttca ttctcactat gcgatttttt tctcataatt
      601 aaaattaaaa taatactcag aggtattaat aaaaacacac gtcccagttt tcctaacagt
      661 cccatactca aagcctcttg gcctgagaag tctgaagcaa gaattacatg tgcaatttca
      721 tgtaaacttg tacctgacca gaccccaaat acttcaggag atattgtaaa aatagaatat
      781 attacagtat atgcaagcga aaatatagtg ccaataagtg cgacaatacc aatactaatc
      841 gcagaatctt tttctctaga ttttaatatt ggagatactg ctgcaatagc tgccgcgcca
      901 cacaccccag tgccaatacc taataatagg atgaggtttt tatctccttt aatatattta
      961 tttagtaaca acattaatcc gatactaaaa aggatgactc caatatcgat taataccaaa
     1021 tcgctacctt ttccaattac atcataaata tttaacttta atccatataa tataatagct
     1081 aatttcagta accgtttaga cgaaaatgcg attcctgaac gatatgcttc agggtaaccc
     1141 ttaaaatgtc tatatagaat cgcaatcagt atagcaattg ttaaagcacc tatcttatct
     1201 aaaaatggta actttgagcc taataaactt ataactgcga tgataaatgt gaataataaa
     1261 ccataaataa aggctttgct ttttaaggac ttcacttttt aactcctcct ttatcaaaag
     1321 cttagcatcg catagttata acgtaaaata aatattgagt atattactca taacattttt
     1381 gttataatag aggtattcaa atgtcaggag acctagttaa tggattcatt aaaagttcta
     1441 actgaagtag ttaaaacgca aagttttact aaagctgcag aaaatttata tacttcacag
     1501 ccatcaataa gtcgcgatat taaacgatta gaactggaat acgatgtaaa aattttcgaa
     1561 tttagacatt ctaaaatgtc tttaacaagt gatggggaga aactatttca atatgcttta
     1621 caacgtgagc gattagaaca aaacttaaga cacgatttga aaatgcaacc tgatataatt
     1681 tcaggagatt taacgatagg gagtagttac acttatggcg aatatcgatt gtcacaacat
     1741 cttgctgatt tagccaaaaa ttatcctgaa ttatacattc atgtgtattt aaataattct
     1801 gatacagtat tacaacatat taagaataac actatcgatt taggtataat cgaaaaagag
     1861 gttcaaagta atattataca cagtagacgt attgctcaag atgaaatagt attaattcgt
     1921 aaaaaatcat catcttcaaa taagtcaata tgttttatca gagaacgtgg atcagggaca
     1981 agagtctatc aggaaaatgc gttatcacaa atgacttcat cctcttattt agtagaaatt
     2041 aacaacacaa atctaattaa aaatatggtc cacgctgata aaggcttttc tattgtttct
     2101 aaatcaacat taacacctta tgatttagaa aagctagaag taacaaactt agacatcaaa
     2161 cgttatttct atttagtcat acataaggat aagtatattg atacgaagct taatgaagtt
     2221 attaaaaatt tgatttcatg aattttgatc tttgtattat ttattctaaa tttaatgcac
     2281 gttctaatga caatctatat aaaaaaagga taaactctca atacataaca ttcataaatt
     2341 atcctttaaa ttattgacaa ttagcgtcaa aatattgaaa cgataccttg taactgatac
     2401 tgtacatatc actttgcatt tctttactaa ccagtgttat aatctatata acgaaaatga
     2461 ttaacaatta atgcaccaat ccccacacta ttgcagtagt gtggggattt tttcgatgct
     2521 ggcttataaa gtcgcctatt aattatttgt tgcgtttact aagccaataa gtataatacg
     2581 caacagcaca gccactgatg actggtgcta tgatgtgaac gaaaatgatt agcaaagtaa
     2641 tgcacctcct ctcttcgtca attgacgcct gagagatagg cgactctatt attataccat
     2701 ctgtgaatat acaagcatat ctacttccga taagtcgtct tatgttatat aactttgttt
     2761 tttatagtat caagacaaga agaaactcgt ttcactcgtt tcaaaaaccc tcatgatttt
     2821 tagagaaaaa ctctcttatt tcatcgtctt taataaaata atatgccatc tttccatctt
     2881 tataaaaatc aagtacctca tttttatata aaagccttaa atgatgtgaa gttgaagcaa
     2941 cactcatttt caatatcaaa gaaatatcac aaacacacaa ctcatcttct ttaatcaaag
     3001 ataatatgat tttcaatttc ttctcatcac aaattttttc taaaatgtta agtaatttct
     3061 tagatttatc atcttctaaa aaacttaaag cattgttaac tttatcctca tgtacacaga
     3121 tcacatcaca agtattttca taactcatat aaaatcacac cttaaattaa aatataaatc
     3181 ctaaaattgt ttgaatagtg tcattttcaa taataataaa taaacctaaa gctatataaa
     3241 taatagccat aatccaacga ctaaatttct caacaatttc tccaattcct ggaatattag
     3301 ctaatttttg tgcagtaaac accaagaaga aaattaaaat taaaaagaca aacagagtaa
     3361 gtaataaatt agtaacactt aatgtcacaa aatacggaac aaataaacca atattatcgg
     3421 cgccacaact tgctatcgta acaattgcaa ccgtaccaac taatttagac aatccttttt
     3481 cattcaattc ttttttagct ctcttttctc cttcacaatc atcataaata gccactttaa
     3541 ttccaagata aattggtatt aaacccaata aacctaatat ccacttttct ggaacataat
     3601 ttaatacaaa agctaaaaac aaactaacta atattaaaat aatagaccct aaatattgac
     3661 caacataaat atctctatat tcttttctag tctttgctct agcaaaaaat attaataaaa
     3721 ttactaataa atcaactgct gtagcaatat aaagaacagc agcagcaaca accgtttgaa
     3781 tcatacatac acctcattca aaaatatttt tgaatgtatt ataacttata tttttaaata
     3841 atcataggtg ctttattcca attgctttat tgacgttgag cctcggaacc cttaacaatc
     3901 ccaaaacttg tcgaatggtc ggcttaatag ctcacgctat gccgacattc gtctgcaagt
     3961 ttagttaagg gttcttctca acgcacaata aattttctcg gcataaatgc gtggtctatt
     4021 tcttattctc gtcttgataa tcatattttt ctgctatctc atcaaaatca tcatctttat
     4081 aaaaaaagaa aaagtaagca ataactccaa tcggaatacc taaaaatggt gtagtaaaag
     4141 tactaaatat tacacacatt aaaattaacc aaaacaaatc ttctaaagac cattttttat
     4201 ttaataaatc attcacaatc tgtttgatag tcataaaaat aaaacactcc tttttagcaa
     4261 actttatcac aatagttatc gctttacagg tctgattttc gtcgttataa tctagttaaa
     4321 tcccgtaagg gcgcacttat gcgttctaaa aagaacgcgt gcaaaaacgt aatcgacctt
     4381 cgtcgatttt tttatttcaa aattaaagaa acggcttgag atattccgag cagttataaa
     4441 aattaatttg cgttgaatat tgctactaca ttcttgaaaa agtgatgtag atttatagcc
     4501 cataactttt ttgaattaca tcgacgatac ggcgtcgaaa gaaaaataaa tagaccgtat
     4561 gaaagaaaaa gctacctcac tttatctggg gtagctttta ttttttatgc ccttattttg
     4621 aattttaaga gggcatttta aagatttagg gttgattcat atagttttat atctaaaact
     4681 tatatacgct tttaaaacgc aaatatgagc caaataaata tatgctattt tcaaaaaaaa
     4741 aatttgagca aaaacaacaa ctatttttta gacactgccc atttacatgc aaatttaaaa
     4801 attagcataa aatactttaa aacttcccca tgtttttcta aattcctgca gggcttttct
     4861 tatcaaaaac ttagaaattt taatttaact ctaaaatctc cgtaagagca taagggaaat
     4921 ttgctatcat tcaaaaatga tagatctggc aaggccagac attccaaggg ttttaagtta
     4981 ttttaaagtg atatcataca aagctgtagt gtcacaaaag tgtgacacta catacagcat
     5041 ttgtcacaaa aataagacag cactttttta cagaaaaaca ataaaaaaag acatcagttg
     5101 tcactaatgt cttaaataat aattttgctt ttcgaaattc caaattgcgg taattgaatg
     5161 tgcttttttt cttcgtctgt cgttttatct tcatcacttg tattaatcaa attaccatct
     5221 tcggcatcgt ctaagtttaa aattttatgc ttttgtttaa gcaatccacc ataacttaac
     5281 atacgttttc gatacaaacc tttttctaaa tcacttacaa tttcttgatt tttttcgtcg
     5341 ttatcagtta aaaagtcaga tgatttaacg gaatattttg atgtctcttc gagtgttata
     5401 aaatcatttg aattattgat taaagatatt atattgtttc atgtttttac ggcgcatata
     5461 aagggcatgt gtttcttcaa gttcagttag aattgtttgc attaaataag cttgcattga
     5521 cttgattgtt tccttttggc ctttaactcc cctatcatgt atagcttttt taagtctttt
     5581 taaagaagtt aatatttcat cctcaatgtc ctctaacatg taatgcatat cttcatgcct
     5641 tgaattaaat gatttttttg ctttaagaat aacagccttt atgatttcta aatctctata
     5701 atcatatttt aataaataat tagttagttg ttctgggaat tcttgcaata gcatttcttt
     5761 atcatcaaaa ttatgtgtaa attgatttga atgattacta atttcatttt tgtactttat
     5821 atcattcaag tcattcatat cattattctc agtatcatta aagtcaatgt cattaaagtc
     5881 agtatcatta gtgttcgatt ttcgaacttc tggacgttcg attttcgaac ttctggacgt
     5941 tcgattttcg aacttctgga cgttcgattt tcgaacttcc ttctcgccgt aaggttcaac
     6001 atcgttttct tctttttcta ttttgtaaat atcacgttct gtgacaatag gtttcattaa
     6061 atatagaata tttggtttat ttaaaccacg tcgtttttga atgagtagac catcgttttc
     6121 taaccctttt tttatttttg ttaatttttc ttttttacaa tttaagattt ccattagctt
     6181 ttcatttgaa taaacaaagt aaatgttacc atcttcatca acccagctat ttttaataga
     6241 taaatttaag cgatcacgta agatagcata ggctattttc atatcattag ttagattttt
     6301 ataattttca ctggtaaaga atactttagg gatttgataa aatctttctt tgtaattttc
     6361 ttgcactgta aaatattgat tttgcatgac aaaaaacctc tttccatatt ttagtttggt
     6421 aagaggtaat aaaacgtttt tatttagctt tacatttatt taatgattta ggtgcttgca
     6481 ctaagatatt attcattata taatacaagt atcgaaaatt atataaataa acagtttcta
     6541 aacgttttat taccaaaccc cgactattac cagtagttgg ggtttttgtt atattaagtt
     6601 tattatagca ctttaaataa acttataaaa gggaaaatat agctttatca agggtttatg
     6661 aacccttgat aaatatcata aacctttaat aaacccttga taaaaaggtt gatgtatgtt
     6721 tatttttatt tattaatcac tttattatta agcattataa gcttataata ttttatcaag
     6781 ggtttatgaa cattttataa agggttgatg atatgaaaag tgtgaaaaag ttgagtgaag
     6841 aattaggggt tagtaagcaa acgattttta ataatattaa gcgattgaat atagagacaa
     6901 taaaacagga aaacacttcg tttattaaag aagataccga tatagaaaaa atcattcaaa
     6961 gagtaaatga aaataaaaag aaatatggtt ttgaaagtac tactgaagac aaacaaaaaa
     7021 aagggtcgga taatattaat tttgaatcga aaagcgatgc tcaaatagta gaaatcctta
     7081 aaaatcagat tgatacttta aataatcaaa ttgaaaaaca agaaagtcgt catgaaacaa
     7141 caattgaatt ttacagaaaa gagttgcaag aaagatcaaa attgcttgaa aatcagcaag
     7201 ttctggcatt agagagtaat aaaaagattc aaaaattaga aaatcaatta gaaaaagaaa
     7261 aacaccttaa ttatcccttt gatacatcta ctaacactag acaaaacgtt gatgcacaag
     7321 aaaaaacata tactactaat cctgtaaata ttaacagaga tcaggaagaa actaaagaaa
     7381 cagagattca atataaggat atatctggaa gtcaaagcga cgaaagtaca caaggtgaag
     7441 aagcaaaaag agaagacgtt ccagctaatc taaatgacaa tgatagtgat atagaagaaa
     7501 agagtgaaga aacggaacct aaaaaggggt tttggagtcg tttgtttggt agctaaaata
     7561 attgattagg cactaaaagt tataaaattt tagtgccttt tatatagtga gaacttctgg
     7621 taatcatcga ttatgtaaat aatatttatt tgctgcatct tgattactta atattaaatt
     7681 gattaacata tttaaaaaat ttaagttgct cagacacttt aaattatcca tattttataa
     7741 accttaaaat taattttaca caacatggct tgtcagaaat ttcggaattg aatagtaaat
     7801 atgccgttat tttgtaccgt tgggttcaag aatatgcccc gattttatat caaataaaga
     7861 atactttaaa aggtattgaa tgtatttacg ctctatataa aaagaagcgc aggtctcttc
     7921 agatctacgg attttcgcca tgccacgaaa ttaggcatat gttagccagt taagggaaca
     7981 acgacatgat aaaatggtaa ttagctatat ttttctaact ttgcaacaga accttttaaa
     8041 atatatatag tttaaatttg cacttgttat tgaataatat gatcacgtag tttattgtaa
     8101 acatagtgtg ttgcatttgt tgcaaaagag gagataacac tatgaaaaca actaaacaaa
     8161 tactaaagga ttttaatatt tcaagacaga cactcatgaa ctggattaat actaaagcta
     8221 ttactactcc aagtaaggat tggagagggt ggtacatttg gtctgaaaaa aatctagaag
     8281 aacttgaaaa acttatgtca gataaaagag aagctaacat aaaggtctct aaagggaatt
     8341 ttgatgaaga attaaatata tacaatagac gatatttagg gtctaaaaaa aggctacttt
     8401 cttttatcga agaagtagtt aataaacaca ccaataatat aaatacggtt gctgacgtat
     8461 ttggtggcac tggcgtcgta tctgatttat tcagaaataa aggcaagaag ataattataa
     8521 atgatatctt gaagtctaat tatgtcactt atttaacctg gtttagtaat gatcctgttg
     8581 atgaagataa aattcgtagg tacatagatt atttaaatac actaaaacct atcgataatt
     8641 atgtttctga taactttggt gacaggtatt ttagcattga taatgctaaa aaaataggca
     8701 ctataagaga agctatagaa gatttagaag atttaaatgg tagagaaaaa gcctttctat
     8761 taacttcttt aatttatgca atggataaag ttgctaatac tgttggtcat tacgatgcat
     8821 atagaaaaac gatggatatg acgaaagaat tatatttaaa aatgcccgta gtaaatttta
     8881 atcgtgataa cgatatatat tgcaaggacg caaatcagtt agtaaaagaa atttctgcag
     8941 acttaattta tatagataca ccatataatt ctcgccaata tagtgatgca tatcatcttc
     9001 ttgagaatat tgttgaatgg aagaagccac ctgtaacagg agtcgctaag aaaatggtag
     9061 ataggtcaaa aacaaaatca aattattcaa ctaataaggc acccgaagca ttcgcagatt
     9121 tgataaaaaa tataaaagca cgatatattc tagtttctta taataatatg gctagaaaag
     9181 ggaacgggcg ttcaaatgct aagatatcaa atgaagaaat tatacatacg ctagaaaaaa
     9241 aaggtaaagt aaaagtattt gaaacaagct ttcaagccta cactactgga aaaagcgtta
     9301 ttgatgacca taaagagatt ttatatttat gtgaagtatc acaaaaagaa gtaaaaaata
     9361 aacagaaaaa tcattacaca ccttcagcta taaattatac aggctctaaa tatagattat
     9421 tagaccagat tatcactttg tttccgaaag aatataataa ctttattgat ttatttgcgg
     9481 gtggctcaag tgttgctatt aactctaatc cgaaaaataa aatcttgatt aatgataata
     9541 tcaaacccct tatcagttta tatcgatact tatctattac tgattatgat agcgtaatca
     9601 aagatattaa ttctttgata gacgattatg gtttatcaag atccagtaaa tatggatact
     9661 ctcactatca tgttgactca tcgaaaggtt tggcaaaata caataaagag gggtatctca
     9721 gattgagaag tgactataat tgtgggaaat ttcatggtaa tgccttagaa aatatcgttt
     9781 tatacctatt aactgttttt ggttttaata atcaaattag atttaacaaa aatggaggat
     9841 acaatctccc tgttggtaaa cgtgatttta atgataaaat gaaagaaaaa ctaaaacaat
     9901 ttatgaaggc tttacatgaa aaagatataa ttttttcatc cgatgatttt agagatgtga
     9961 ttccattatc aaatgatacg tttctttatg ctgacccacc ctattcgatt acttctgcga
    10021 cttatacaga gaatagtagt tggagtgcta aagatgacgc tgatatattt gattatcttg
    10081 ataaatgtca tgaaaatggt attaaatttg cgttatctaa tgtcgctcaa cacaaaggta
    10141 cagtaaatga ggaactatta aagtgggcaa agaaatataa tattcattat ttagatttca
    10201 attataataa ttcaaactac caatctacag caaaatcaaa aattacacat gaagtattaa
    10261 taaccaacta ctaaagttgg ttatttttta tgatatgatt attaaaaata cgtatcaaag
    10321 taggtgttat tgttgaaatt aggcgataaa aatcaaatat taaattttgc aaatacaaat
    10381 ggaagacgta atgacttgat taatgcgtat acaatctata tgaatatttt aaatgagagc
    10441 ttcgagagtg gtatttatat ttgggacaga tttcctaata gtcttggtca atttcatttt
    10501 tatagtagag ccctagaaga gtccaaagat gtttttcagc aacatggacc ttatgattat
    10561 atttgtaaaa aattagagtt acctgagtat cgagaagctt ttcataatat ggataaagaa
    10621 aaaattattc agttagaagg tggtaacgat tttataaaaa agctagataa cggtgtagaa
    10681 gatagaagtc gtcattatac tagtacttta accaaaatag gatttataca tgaagacaga
    10741 caattaagtt cagtgggcaa actatttatt agtgaatcag atcccgtaag aaatgatttt
    10801 gaaaaactac tacctatcga taaaattaac ttattgctgt tacgtcaagg tttaaaaata
    10861 agagtatata ctgatgatta tcagaaatat tattctccaa taatgctgtt attatacatt
    10921 ttatttaaaa atgaaaaagt aaatgctaaa gatttattta cactgcttaa cactatcaca
    10981 ccttattttc cttttgatta taaagaaata tctgattctt tttcaaaaga caatgtaaga
    11041 gacgtaattc aaaaatatga aaaattattt atagctgagc cattagtaga gggtaagaga
    11101 ttagaaaaag aagaatttta taaaaagttt tctaataata aaacaagcaa agaccaacat
    11161 atatattttg atttttataa taaattatta gactttgtaa ctgatcctgc agactcaact
    11221 tattcacaat tagaagaatt atttgaagat aaatataaga agaacgtatt aaacaatacg
    11281 ttcggtcaaa aaaagaagtt tttagaattt aatgtaagtg attataatga atttattgac
    11341 gtaaattatg attctaatat actatcctta gactctttta atagtaactt ctatattaag
    11401 tttttcaatt caaaacgtaa taaagatatt catgattata aagatatgct taaaagattt
    11461 actagagcta ctggaattat tgaaattaat aatggagttg ttaatttagc atacagagat
    11521 gtttggatag aatattttaa atatgtagat ttcgatggtt taatatttaa tacagatacc
    11581 aaaaattcag ctgcagaata tgagtattca gtggattcgg tgttctataa agatgttact
    11641 ataaataaaa tattcgatat tactgacgaa caaatgaatg atattattga atccataaaa
    11701 aacaaattga gtatcgattc tgtagaaagt attaaaaaga atctggttaa tcgtaatgat
    11761 atattgttta aagaattcat taattcagaa tttcccctaa aaaagacaat gagtatactt
    11821 aatatgttta gtgatagaag taatgataaa gaaattaaaa aaattgtggg ctctgaagca
    11881 ggtgttccta caatttacga atacatgatt ggtattgctt ggtatcatat tagtaataaa
    11941 gaatatgatg tattttctag ctttaattta actatgaatg ccaatttcct tcctgaaact
    12001 catgcgggtg gtggagcagg agatattgtt gtaaagtata atgataatac actaatgtta
    12061 gaagttacat taatgaataa gaatgctcaa aaacgtggcg aatgggagcc tgtactacgt
    12121 catgcaacaa acttaacaat cgatgaacac cctaagaaag taagaacact atttatagct
    12181 gatgaactag atgaaaatac aattaatata tggcgtgctg tagcttctgt tccaatgaaa
    12241 tcaactactg gcaaaaaaga ctatgccgag aatttaatta tcatgccttt tacaacagct
    12301 gaaattatta ctttgatgaa tagaaatatt gatgaaaata aaatatttac atccattgat
    12361 tcgtcgtatt ctcagctaaa aagtaacttt aattctaatt ggcgtaatga tattattaat
    12421 agtttttaaa aatagaacca tgtctgatcc tggcatggtt ctacttgtgt ctaaaactca
    12481 tgaacggtca agtaacaaaa tacgaattat gtatcctatc aaatcccgtt aaatcagggg
    12541 tttgattttt ttataattca gagttatcat aacgataata aaagttcctt aataagatac
    12601 ataatgagaa tgaatggagc tgatttatat gaacattgtt gaaccgattc gcgacataca
    12661 gatgataaaa caaatgaagg aatcactaaa ttattacgga acaaaaagag atgtttttct
    12721 cttcgtacta gggattaact gtgggctgag agtaagcgat atgttgatcc tgaaaaaagg
    12781 ggatatcaag gattatcaaa tcagaataaa ggaaagcaag acaaagaagc ataaagtgat
    12841 tccactccat catattaaaa atgaaattga tgaatacatt caatttttag aagatgatga
    12901 ttttttattc aagagcaatc gcaaagataa acacggaaat caaaaggcaa taaatcgtat
    12961 cagagcgtat aaaatattaa atgaagcagc caaaaatatc ggcttagaga atattggaac
    13021 acatagcatg cgtaaaactt ttggttacca ttattataaa agtactaatg atgtcgcatt
    13081 attgatggat atcttcaatc attcatcgca atctgtaact ttacgttata tcggtatcaa
    13141 tcaagatatc atgaatgctt caataagtaa tgcgatgaaa ggtttgtacg attaattatt
    13201 ttcggttctg ttgcaaagtt agaaatatag tataatagtc aacaaaaatg aggtgcagag
    13261 gatgaattat ttcagatata agcaatttga caaagatgtc attactgtag ccgttggcta
    13321 ctatctaaga tatgcattaa gttatcgtga tatatctgaa atattgagag aacgaggcat
    13381 ctatgttcat cattcaacaa tttatcgatg ggtacaggaa tatgctccta ttttgtatca
    13441 aatttggaag aaaaagaata agcaagctta ttataaatgg catatagatg agacgtatat
    13501 caaaattaaa gggcaatgga attatttata tcgcgctatt gatgcagatg gccatacact
    13561 agatatttcg ttacgtaaga aacgagataa tcactcagca tatacgttta ttaaacgtct
    13621 tattaaacaa tttggcaaac ctcaaatgat aattacagac caagcccctt caacgaaggt
    13681 ggcaatgtcc aaagtgatta aagattttaa acttaccccc aactgtcatt gtacctctaa
    13741 atatttaaat aatctcattg aacaagatca tcgtcatatc aaagtaagga aaataagtta
    13801 tcaaagtatc aatacggcaa agaatacgat caaaggcatt gaatgtattt atggactata
    13861 taaaaagaac cgcagatctc ttcagatcta cgggttttcg ccatgccgtg taattagcat
    13921 catgctagct agttaatacg aagtattatt ttaaacataa ggttagacac ttatttttta
    13981 actttgcaac agaacctcct atttttagta atatttatag ccctaacagt tagataaact
    14041 gcatttataa aacccaaaat agtatatgga attaaaatat ataaattttc taattgaact
    14101 aagaaagtta acccaactaa aaataaaaca ttcaaaacgg tagacataat aaaagctata
    14161 tctaactcat ttttttattc aaaatacatt cctccttttt aaaaatttta ccatagttgc
    14221 tttattccaa ttgctttatt gatgttgagc ctcggaaccc ttaacaatcc caaaacttgt
    14281 cgaatggtcg gcttaatagc tcacgctatg ccgacattcg tctgcaagtt taattaaggg
    14341 ttcttctcaa cgcacaataa attttctcgg cataaatgcg tgtctatgcg tagacatgga
    14401 gacacttcag aattatggag tgattacatg agtttaacta tttttcttta ttcagtttta
    14461 ggaagtttat tagcaaatta tatctacgaa aaatcttcga aaagaagttc agctcatgat
    14521 aacgagttta cctatgatga atgaagtcat tggaaatcca ctactagata aatttatgaa
    14581 agatttaatt attcaaattt tagcaatgat ttcagaacaa gaaagaaatg aaagtaaacg
    14641 tcgacaagct caagggattc aagtcgccaa agaaaaaggt atatataaag ggagacctgt
    14701 tctgtattct cccaatgcta aagacccaca aaagcgttta gtttattacc gagttgttga
    14761 attacttgaa cagggtaaat ctataagtac tatagctaaa gaagttggta ttacacgtca
    14821 aactatatat agaataaaaa atagtaaata aaataacata gacaataatc tatatagatg
    14881 ttaatctatt taatatctag gaggtttatt aatgtcttat aaagaactat caacaatatt
    14941 aaaaatttta tcagattcaa gtaggttaga aatattagat ttactttctt gtggtgagct
    15001 atgcgcttgt gacttattag aacactttca attctcacaa cctacactaa gtcatcatat
    15061 gaagtcatta gtagataatg aattagttac aacacgaaaa gacggcaata aacattggta
    15121 tcaacttaat catgctattt tagatgatat tatccaaaac ttgaacatca ttaatacatc
    15181 taatcaaaga tgtgtatgta aaaatgtgaa atcaggtgac tgttgatgac tattttagca
    15241 attgtaattt ttcttttaac tttaaccttt gtgatttggc aaccaaaagg tttagatatt
    15301 ggtattacag ctttaattgg agctgttgtt gctatcatta caggagtcgt aagtctttct
    15361 gatgtattag aagtaacagg tattgtttgg aatgcaactt taacttttgt ggctgttatt
    15421 cttatttcat taatattaga tgaaattggt ttttttgaat ggtctgcgat acatatggtc
    15481 aaggcttcaa acggtaatgg cttaaaaatg tttgttttta ttatgttact tggagcaatt
    15541 gtagcagcat ttttcgcaaa tgatggtgca gctttaatct taacgcctat tgtattagcg
    15601 atggtaagga atctaggatt taatcaaaaa gtgattttcc cctttattat tgccagtggt
    15661 tttattgctg atactacatc acttccctta attgtaagta acttagttaa tatcgtttct
    15721 gcagattact tcgatattgg atttattgaa tattttagcc gaatgatcat tcctaatata
    15781 ttctctctga ttgctagtat tctcgtttta tggttatatt tcagaaaatc catacctaaa
    15841 acgttcgata cagaaaatct atcagatcct aaaagtgcaa ttaaagattc taagttattt
    15901 aagctttcat ggatagtatt agcagtacta ctcgttggat atcttgttag cgagtttatc
    15961 caaattcctg tatcaattat tgctggtatt attgctttta tctttgtaat attagctcgt
    16021 aaatctaaag cagttcatac aaaacaagtg attaaaggtg caccatggaa tatcgttgta
    16081 ttctctattg gtatgtatct tgttgtgttt ggactaaaaa atgtaggtat tacaacgatc
    16141 cttggggatg ttttaacaaa catttcaaat tatgggttat ttagcagcat catgggtatg
    16201 ggctttatag ctgctttctt atcttcgatt atgaacaaca tgccaactgt tttaatagat
    16261 gcaatagcaa ttggccaatc cagtgctaca ggaatattaa aagaaggcat ggtttatgcg
    16321 aatgtcatag gttctgattt aggacctaaa attacgccaa ttggttcttt agcaacatta
    16381 ttgtggctac atgtcttaac acaaaaaggt gtgaagattt cgtggggaac atactttaaa
    16441 actggaatta tcatcactat tccagtccta tttgtaacac tcttaggttt ataccttaca
    16501 ctaatcatat tttaagaaaa ggggctttaa ttatggataa gaaaacaatt tattttatat
    16561 gtacaggaaa ctcttgtcgt agccaaatgg ctgaaggttg gggaaaggaa atattgggtg
    16621 aaggttggaa tgtctattct gctggtattg aaacacatgg tgttaatcct aaagcaatag
    16681 aagctatgaa agaagtagat attgatatat caaaccatac gtcagacttg attgataatg
    16741 atattttaaa acaatcagat ttggtcgtaa cgttatgtag tgatgcagac aataattgtc
    16801 ctattttacc accaaacgtt aaaaaagaac attggggttt tgatgatcca gcaggtaaag
    16861 aatggtcaga attccaacgt gttagagacg agattaaatt agctatagaa aagtttaaat
    16921 tgagataatc ataaacacct cttatttagt taataagagg tgttttgcca tttaaagaac
    16981 aaaatttgtg ccatataact ccaaaactga caaacgctct ctttttttcc tctcttatta
    17041 ttaaaatctc ataatacatg attaacatat attttgggac gctgtgagaa acgctcattt
    17101 gcattgacaa tccatttatc aagataatcc attatcatgt ttaattctat aaactgtctg
    17161 tcttgtaata ttaacctctt tcgcaatctt actaattgct tgcccttctt ctaacatttc
    17221 gacaactcga tgatagataa cacgtttttg gggatctttc gcgttcggtg aataaagcaa
    17281 aggacgccct ttatatacgc ctttttcttt cgcaacttga atcccttgcg cttgtcgacg
    17341 tttactttca tttctctctt gttctgaaac cattgctaat atttgaatga ttagatcttt
    17401 cataaattta tctaataata gattgccaat tacttcattc atcataggta agctggtaat
    17461 cattaactga acgtcttttt cttttaaata attcacagtt tcaataattt catcatagtt
    17521 acgtcctaaa cgatcaatag attccacaac gaatcgatct cccattctga caaaattgag
    17581 agcttcttga aatataggtc tattttccac tgactttccc gactgtttct ctgtaaagat
    17641 tttctccaca ccaaatgtct ttaaattatc caattgtctt tctaaatttt gatctatcga
    17701 agatactctt gcataaccta taatcattta tttttcactc cgaaatt
//
