LOCUS       NZ_MH785247            20630 bp    DNA     circular CON 21-JUL-2023
DEFINITION  Staphylococcus aureus strain tu2 plasmid pMW2, complete sequence.
ACCESSION   NZ_MH785247
VERSION     NZ_MH785247.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN09846915
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20630)
  AUTHORS   Bukowski,M., Piwowarczyk,R., Madry,A., Zagorski-Przybylo,R.,
            Hydzik,M. and Wladyka,B.
  TITLE     Prevalence of Antibiotic and Heavy Metal Resistance Determinants and
            Virulence-Related Genetic Elements in Plasmids of Staphylococcus
            aureus
  JOURNAL   Front Microbiol 10, 805 (2019)
  REMARK    DOI: 10.3389/fmicb.2019.00805
REFERENCE   2  (bases 1 to 20630)
  AUTHORS   Bukowski,M., Hydzik,M., Sabat,A.J. and Wladyka,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-AUG-2018) Faculty of Biochemistry, Biophysics and
            Biotechnology, Department of Analytical Biochemistry, Jagiellonian
            University, Gronostajowa 7, Krakow, malopolskie 30-387, Poland
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/21/2023 01:11:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 25
            CDSs (total)                      :: 25
            Genes (coding)                    :: 21
            CDSs (with protein)               :: 21
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 4
            CDSs (without protein)            :: 4
            Pseudo Genes (ambiguous residues) :: 0 of 4
            Pseudo Genes (frameshifted)       :: 3 of 4
            Pseudo Genes (incomplete)         :: 1 of 4
            Pseudo Genes (internal stop)      :: 2 of 4
            Pseudo Genes (multiple problems)  :: 1 of 4
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MH785247.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20630
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="tu2"
                     /isolation_source="deep wounds and lesions"
                     /host="Farmed turkey"
                     /db_xref="taxon:1280"
                     /plasmid="pMW2"
                     /geo_loc_name="Poland: Wroclaw"
                     /collection_date="2008"
     gene            228..904
                     /locus_tag="D0Y82_RS00005"
                     /pseudo=""
     CDS             228..904
                     /locus_tag="D0Y82_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <915..1197
                     /locus_tag="D0Y82_RS00135"
                     /pseudo=""
     CDS             <915..1197
                     /locus_tag="D0Y82_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2406..3023
                     /gene="cadD"
                     /locus_tag="D0Y82_RS00015"
                     /old_locus_tag="D0Y82_h00015"
     ARG             2407..3020
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            3042..3389
                     /locus_tag="D0Y82_RS00020"
                     /old_locus_tag="D0Y82_h00020"
     CDS             3042..3389
                     /locus_tag="D0Y82_RS00020"
                     /old_locus_tag="D0Y82_h00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3558..3650
                     /locus_tag="D0Y82_RS00025"
     CDS             3558..3650
                     /locus_tag="D0Y82_RS00025"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3862..4836
                     /locus_tag="D0Y82_RS00030"
                     /old_locus_tag="D0Y82_h00140"
     CDS             3862..4836
                     /locus_tag="D0Y82_RS00030"
                     /old_locus_tag="D0Y82_h00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072390.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKATLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(4956..5771)
                     /locus_tag="D0Y82_RS00035"
                     /old_locus_tag="D0Y82_h00030"
     CDS             complement(4956..5771)
                     /locus_tag="D0Y82_RS00035"
                     /old_locus_tag="D0Y82_h00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5764..7207)
                     /locus_tag="D0Y82_RS00040"
                     /pseudo=""
     CDS             complement(5764..7207)
                     /locus_tag="D0Y82_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(7179..7772)
                     /locus_tag="D0Y82_RS00045"
                     /old_locus_tag="D0Y82_h00045"
     CDS             complement(7179..7772)
                     /locus_tag="D0Y82_RS00045"
                     /old_locus_tag="D0Y82_h00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(8036..8416)
                     /gene="blaI"
                     /locus_tag="D0Y82_RS00050"
                     /old_locus_tag="D0Y82_h00050"
     ARG             complement(8040..8416)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8406..10163)
                     /gene="blaR1"
                     /locus_tag="D0Y82_RS00055"
                     /old_locus_tag="D0Y82_h00055"
     ARG             complement(8410..10163)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10270..11115
                     /gene="blaZ"
                     /locus_tag="D0Y82_RS00060"
                     /old_locus_tag="D0Y82_h00060"
     ARG             10271..11112
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11484..12017
                     /locus_tag="D0Y82_RS00065"
                     /old_locus_tag="D0Y82_h00065"
     CDS             11484..12017
                     /locus_tag="D0Y82_RS00065"
                     /old_locus_tag="D0Y82_h00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823239.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001823239.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVVGNPLLDKFMKDLIIQILAMVSEQERNESK
                     RRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRIIYHRVVEMLEEGQSISKIAKEVNIT
                     RQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12431..12724
                     /locus_tag="D0Y82_RS00070"
                     /old_locus_tag="D0Y82_h00075"
     CDS             12431..12724
                     /locus_tag="D0Y82_RS00070"
                     /old_locus_tag="D0Y82_h00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12776..14710
                     /locus_tag="D0Y82_RS00075"
                     /old_locus_tag="D0Y82_h00080"
     CDS             12776..14710
                     /locus_tag="D0Y82_RS00075"
                     /old_locus_tag="D0Y82_h00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14714..15025
                     /locus_tag="D0Y82_RS00080"
                     /old_locus_tag="D0Y82_h00085"
     CDS             14714..15025
                     /locus_tag="D0Y82_RS00080"
                     /old_locus_tag="D0Y82_h00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            15037..15663
                     /locus_tag="D0Y82_RS00085"
                     /old_locus_tag="D0Y82_h00090"
     CDS             15037..15663
                     /locus_tag="D0Y82_RS00085"
                     /old_locus_tag="D0Y82_h00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15901..16530
                     /gene="mobV"
                     /locus_tag="D0Y82_RS00140"
                     /pseudo=""
     CDS             15901..16530
                     /gene="mobV"
                     /locus_tag="D0Y82_RS00140"
                     /inference="COORDINATES: protein motif:HMM:NF013258.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16624..17169
                     /locus_tag="D0Y82_RS00100"
                     /old_locus_tag="D0Y82_h00105"
     CDS             16624..17169
                     /locus_tag="D0Y82_RS00100"
                     /old_locus_tag="D0Y82_h00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(17211..17495)
                     /locus_tag="D0Y82_RS00105"
     CDS             complement(17211..17495)
                     /locus_tag="D0Y82_RS00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_254231383.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCSKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            17553..18413
                     /locus_tag="D0Y82_RS00110"
                     /old_locus_tag="D0Y82_h00110"
     CDS             17553..18413
                     /locus_tag="D0Y82_RS00110"
                     /old_locus_tag="D0Y82_h00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18500..18841
                     /locus_tag="D0Y82_RS00115"
                     /old_locus_tag="D0Y82_h00115"
     CDS             18500..18841
                     /locus_tag="D0Y82_RS00115"
                     /old_locus_tag="D0Y82_h00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19080..19151)
                     /locus_tag="D0Y82_RS00120"
     CDS             complement(19080..19151)
                     /locus_tag="D0Y82_RS00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19300..19485
                     /locus_tag="D0Y82_RS00125"
                     /old_locus_tag="D0Y82_h00125"
     CDS             19300..19485
                     /locus_tag="D0Y82_RS00125"
                     /old_locus_tag="D0Y82_h00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19704..20447)
                     /locus_tag="D0Y82_RS00130"
                     /old_locus_tag="D0Y82_h00130"
     CDS             complement(19704..20447)
                     /locus_tag="D0Y82_RS00130"
                     /old_locus_tag="D0Y82_h00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843757.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEAKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10271..11115
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7431..17724
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1255..1402
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17554..18413
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19705..20447)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15902..16176
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 attcaaagtg ctataataac cttaatataa caaaaacccc aactactggt aatagtcggg
       61 gtttggtaat aaaacgttta gaaactgttt atttatataa ttttcgatac ttagattata
      121 taatgaataa tatcttagtg caagcaccta gattattaaa taaacacaaa aaatgtaagc
      181 gttttattac ctcttaccaa actaaaattc ggaaagaggt ttttattatg tcaattaaac
      241 tttacaacat aaatgaggaa tacagagaaa agttttatca aataccgaaa gtatttttta
      301 caaatcctaa atatatcaag ttatccaatg atgcaaaaat ggcatggggt attcttagag
      361 atcgtttaga tttatcaatt aaaaatggtt gggttgattc taaaacaggt aatatttatt
      421 tttattacaa aaatgaaaac ccacaaaata tattaaattg taaaaaagat aaagtaatta
      481 aaataaagaa agaacttaat tgaagccgaa ttactactac aagaaagaca aggtttaaat
      541 aagacaaata aactttattt agttaaacca gaagtaacag aagatgatat ttataaaatt
      601 caaaagcaag aaaacactgt tgagagcagc aatggcaagg aagtcggaaa aaccgacttc
      661 aagaagtcga taaaacagaa tctaatgata ctgaacttag ctatactgaa tctaacaata
      721 ctgaaataaa tgatatgaat gacttgaatg atatagagtc cgaaaatgaa attagtaatc
      781 attcaagtca atgcaaggtt atttaatgca aacaatttta actgaatttg aagaaacaca
      841 tgcactttat atgcgccgta aaaacatgaa acaatataat atctttaatc aatcattcaa
      901 atgattttat aacaatcaaa gatacatcaa aatatttcgt taaatcatct gactttttaa
      961 ctgatagcga tgaaaaaatc aagaaattgt cagtgatcta gaaaaagatt tgtatcgaaa
     1021 acgtatgtta agttatggtg gattgcttaa ataaaaacat aaaattttaa acttagacga
     1081 tgctgaagat ggcaatttaa ttaatacaag tgatgaagat aaaatagcaa atgaagaaga
     1141 aaaggcacat tcgattacgg caattttgaa aagcaaaatt attatttaag gcattagtga
     1201 taactgatgt ctttttttat tacttttttg taaaaaaagt gctgtcttat ttttgtgaca
     1261 aatgctgtat gtagtgtcac aaaagtgtga cacttgagct ttttatgacc ccacacaaaa
     1321 acattttcga agccttgaaa tatctggctt tgccagatcc cccattcatt gatggggaca
     1381 aatttccctt atgctcttac ggagatttta gagttaaatt aaaatttcta agtttttgat
     1441 aagaaaagcc ctgcaggaat ttagaagaac gtggggaagt tttaaagaat tttatgctaa
     1501 tttttaattt gcatgtaaat gggcagtgtc taaaaaatag ttattgtttt tgctcaaatt
     1561 tttgtttttg aaaatagcat atatttattt ggctcatatt tgcgttttaa aagcgtatat
     1621 aagttttaga taaaactata tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc
     1681 aaaataaggg cataaaaaat aaaagccccc ccagataaag tgaggtagct ttttctttcg
     1741 acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta taaatctaca tcactttttc
     1801 aagaatgtag tagcaatatt caacgcaaat taatttttat aactgctcgg aatatctcaa
     1861 gccgtttctt taattttgaa ataaaaaaat cgacgaaggt cgattacgtt tttgcacatg
     1921 tcgatttatc cgacgtataa gtgcgccctt acgggattta actagattat aacgacgaat
     1981 tttagacctg taaagcaata acaattaggt ctaccaggta gataaagtgt acaaagtaga
     2041 accgaaaaag ttatttattt tgaagatttt tcgtagatat aatttgctaa taaacttcct
     2101 aaaactgaat aaagaaaaat agttaaactc atgtaatcac tccataattc tgaagtgtct
     2161 ccatgtctac gcatagacac gcatttatgc cgagaaaatt tattgtgcgt tgagaagaac
     2221 ccttaactaa acttgcagac gaatgtcggc atagcgtgag ctattaagcc gaccattcga
     2281 caagttttgg gattgttaag ggttccgagg ctcaacgtca ataaagcaat tggaataaag
     2341 cacctatgat tatttaaaaa tataagttat aatacattca aaaatatttt tgaatgaggt
     2401 gtattatgat tcaaacggtt gttgctgctg ctgttcttta tattgctaca gcagttgatt
     2461 tattagtaat tttattaata ttttttgcta gagcaaagac tagaaaagaa tatagaaata
     2521 tttatgttgg tcaatattta gggtctatta ttttaatatt agttagtttg tttttagctt
     2581 ttgtattaaa ttatgttcca gaaaagtgga tattaggttt attgggttta ataccaattt
     2641 atcttggaat taaagtggct atttatgatg attgtgaagg agaaaagaga gctaaaaaag
     2701 aattgaatga aaaaggattg tctaaattag ttggtacggt tgcaattgtt acgatagcaa
     2761 gttgtggcgc cgataatatt ggtttatttg ttccttattt tgtgacatta agtgttacta
     2821 atttattact tactctgttt gtctttttaa ttttaatttt cttcttggtg tttactgcac
     2881 aaaaattagc taatatccca ggaattggag aaattgttga gaaatttagt cgttggatta
     2941 tggctatcat ttatatagct ttaggtttat ttattattat tgaaaatgac actattcaaa
     3001 caattttagg atttatattt taatttaggg tgtgatttta tatgagttat gaaaatactt
     3061 gtgatgtgat ctgtgtacat gaggataaag ttaacaatgc tttaagtttt ttagaagatg
     3121 ataaatctaa gaaattactt aacattttag aaaaaatttg tgatgagaag aaattgaaaa
     3181 tcatattatc tttgattaaa gaagatgagt tgtgtgtttg tgatatttct ttgatattga
     3241 aaatgagtgt tgcttcaact tcacatcatt taaggctttt atataaaaat gaggtacttg
     3301 atttttataa agatggaaag atggcatatt attttattaa agacgatgaa ataagagagt
     3361 ttttctctaa aaatcaggag ggtttttgaa acgagtgaaa cgagtttctt cttgtcttga
     3421 tactataaaa aacaaagtta tataacataa gacgacttat cggaagttat ctatcatcgt
     3481 atattcggag atgatataat atacaggtcg cctatctctc aggcgtcaat tcagacgcag
     3541 agaggaggtg cattactttg ctaatcattt tcgttcacat catagcacca gtcatcagtg
     3601 gctgtgctgt tgcgtattat acttattggc ttagtaaacg caacaaataa ttaataggcg
     3661 actttataag ccagcatcga aaaaatcccc acactattgc agtagtgtgg ggattggtgc
     3721 attaattgtt aatcattttc gttatctaga ttataacact ggttagtaga ggaatgcaaa
     3781 aagataatat tttaagtagt ctttttggat attatcatat gatatattta tgtaaattga
     3841 ttttttatta aaggagcata tatgagtaat actaaaatta aatatcaaat ttttatttca
     3901 tcaacttatt tagatttaat agaagagcgt caagcagtag tagaagcagt tttaaacagt
     3961 aataatattc cagcaggtat ggaacttttt aactcaagta gtaaaagcca atgggaaata
     4021 ataacacaat ggatcaatga atcagatgca gtgatattat tgttaggttc tagttatgga
     4081 acaattgata gtgaagaaaa tattagctat acagaaatgg agtacaattt tgctaaatct
     4141 ttaggtaaac ctatatatgt ttttgagatg aataaagcat ctaccgaatc cgcggaaaag
     4201 tctaaaaaat tagatgagtt taagacaaaa gttaaagaaa atagactaat tagtccaaat
     4261 attaatgata tttcggaatt aaaaagtaaa gtatctcaga ctttaatgca aagtgtacct
     4321 agtgaaatta aagaaaatag tggatggata agagtacagg attgtggtaa aaatgtaaaa
     4381 aaattaaaaa aattggatgc tatacaaaga gatttagata catatgattt tttgaaagaa
     4441 gaactttata aaatattcat gtatgtaaaa actttttatt tccagcacac accatttgat
     4501 gatagttata ttgaagatat agaaaactac ctgctaaatt atgaaaataa tccacataaa
     4561 tcattcatga aaataaaagt ttatgattat aaaaactttt taaaacattt aaaaaacata
     4621 ttgattttaa ttaaacaagg aaaaaagcca ttagctcaag ccggtcattt taaattaagc
     4681 ttttacgaag aggatttaaa attgttacaa aaaaattata aggctacgct agtcgatatt
     4741 aaaggattga ataaacattt ttataaggaa tgtgataggt gcttaaaagc atataatatt
     4801 tttattgagg gtataaataa acatttatat gaatgatata agtacaccct aatcatacat
     4861 atataattgt tgtcacttta ctcgatatat gagaatgact ttacctaata aatgagaaaa
     4921 gcaacgcact atattaaaat gcgttgcttt ttctattatc gaatacctat aactaaacta
     4981 tctctagctg tttctacaac ttctgtactt attttatcta aaccatttat atccataatt
     5041 ctgtctatct gcgcaaataa acgatgaatc agcctaaaat tcccttttgt aattttaata
     5101 atcgtcgtta ttgcctcata atcagtaaag tcttcgagtt ttaaatcaaa tcctaagtct
     5161 tgccacttat attctaatat atgatgcgtc tcatctttac ttagattatc aaattcatgc
     5221 gcaaaaccta tacgcgaata tagttgagga taacgagata gttttttctc tatacccggc
     5281 ataccaataa atatcattgc taaattatgt tcatcataaa tagctcttaa ttgctctaaa
     5341 tgttgcactt taaggcgatc aatctcatct actataatta aatcaatata tttaaacata
     5401 tcactataat gtttactatg ttcatgtcca tacttattta caacatgtaa tttttgaccc
     5461 aaatcaatga ttgcagtaat actatataaa tcattcctta atttagtttg tttttctgct
     5521 ggtgcattat aaaatatttt atccaccgat agtatgtcat cggtcgtttt actagctaaa
     5581 tcttcccaac ctctatggtt aacttgtttt tcaatagtat cccaatttgt gtaataccta
     5641 gacgataaag tttttccgac accaggttga ccataacata taccaatata ctgatattta
     5701 atacaagcat cacaaaattc agcaaagcgt ttatactctt tcgtttcaat gaaattttga
     5761 tttttagtca ttacgatatc tctttaattt tttgacgttt ttagtcgttt cttgaggtga
     5821 ataaccacaa tttttttctt ccttaattaa ttccgtggta cttggactag caatattttg
     5881 ttttaagtgt tttcttctct gactacgagc gtgctgtatg tcttttatat ctatggagta
     5941 atcagctatt tctggacata tagcagtaca aagaaattca tctctataaa acacacgtat
     6001 ttcagccata tcatttgggt tataacgaat cagtacatat tcacctacat aagcttctag
     6061 attagtatta ctgtatcgaa aaccttgaaa atgaatgcca tctgaatgaa cttttctaga
     6121 tttaggtatt tccaacaata ataaatcaag ttgttctaag ctacttggca tattagggaa
     6181 aaagtgatta ctattccaat gactgatagg cgtggtatga atagtactat gttctttttg
     6241 attataatct tcaattaaaa agtaacgtaa tttttcttca aaattgtgaa aatttattag
     6301 attactagga gtatcattat tgtttatata tccaggcagt tgttctaaga aagtttgatt
     6361 aactgtctga aagaatcgtt ctatttttcc acgaccacga ggaacaccaa ctttcgaaaa
     6421 catcaagtta attttcaaat caatagcgac ttgttccata tgatgtgaag taaagtcact
     6481 tccatgatct gtgtagaatt tttcgggtat accacacact ggccaattgg tatcattttt
     6541 attccatatt gcttggtgta gtgttaatgc tgtgttttga gcattggggg gcatcaaaac
     6601 ttaagaaata gcctgcaatt gcacgactat agtcatccat aataatagtt agccatggtc
     6661 tattgatatt acctttttgg tctaatataa agatatctag caaagtatgg tctgcttgcc
     6721 atatttcatt gggtctcgag gattctctaa tttgtattaa atcgtactta ttttgatagt
     6781 atttttcacc ctgatgagag aaatcaataa cagacttagg catcgcttta ataacactat
     6841 aaatttgttt ataacttggt atatcaaaat tattttcttt acagtaatta gtgattttcc
     6901 tatgaattgt ggctatacta tttcttttat tcataagcgc aaggcgttca atttcatcaa
     6961 ttatctttgg ttctatttta cgtgttcctt tatcagctct tgtcgcatag attagtcctt
     7021 taagtccttg ttctttatat gacttattcc acctataaag ggtgcttaac gcaatccctt
     7081 tacttttaga aatacttgat aaagattgtt cgcctaggat aaaaggtttt ataatattgt
     7141 acttttgagt agctttttta cgtttggctt cagaaaaatt agttagatac ttctccttgt
     7201 ttttcatctt ccttgtcctc caatttattg aggtaacgat aaattgttgt acgtgaaaca
     7261 tgccactgtt ctgcaattgt cttaattggc gtgccattat cataaagggt cttaagtaag
     7321 tttaaatctt tttgatttaa tttttctggt ctgcctccat atcggcctct agcacgtgct
     7381 gcaattcggc cagctgaaga acgctctaaa attaaattac gttcaaattc tgcaaatgct
     7441 gcgaataaat gaaataataa ttgtccagtt gaacttgatt tatccattgt tatattttct
     7501 tctaaactat ggaaacttac acctcgttcg ttaagctcat taactaatgt gattaaatcc
     7561 tccatattac gtcccaatct atctaatctc caaacaacaa tcgtatctcc tgacctcgca
     7621 aattcaattg ctttatctaa accaggtctt ttactttttg aaccactcat atggtcatta
     7681 aatatctttt cacaaccata tgtatttaat cgatcctcct gtaaatttaa attttgtaat
     7741 ccagttgaaa ctcttgcata acctattttc aaaatacaaa cctcctatat acatcttcag
     7801 tgtaccataa cttaattaca aggtctttta tgaacataga ttttttgttg ggtttttgaa
     7861 cacataatcc tatgtaattc ttacttattt agacataaaa gaagagtgta cagaaaatgg
     7921 ttattttctg tacactctca tctttaataa tatattttaa atgtcattaa caaaactaat
     7981 ttaataagag tcaagcatag tttacatatg tattatgttt gaaacatacc tctaattact
     8041 ttttactaat atcatttaaa atatctcgca attcttcaat ttctttgtta tttaattctt
     8101 catttttcgc aaaattcaac actaaacttt tcatatcccc tccatacagt ttattaagaa
     8161 aggttttagc agttttcatt ttaatatcgt cttctttaat atttgatgag taaaaataaa
     8221 tattttctga tttgtatcgt tttataatct cttttttata tagtcttgtg attaatgttc
     8281 taatcgtttt atcactaact tctttatatt tttgaatttc aactacaatt tcattagctg
     8341 atactgattt tttatcccat attatattca taacatccca ttcagccata gatatttcaa
     8401 cttgcttatt ggccatttaa aacacccatt ccttttaata ttttttcact tattaattca
     8461 gcatttttcc cagacgggtt tccatctgat aaatgtgtag caaaataata cttatcatga
     8521 tttgtaatta cgtaacctac aaaccaccca ttattatact tcccgtttac tatacctgta
     8581 cctgttttcc catacagttc atacttttca tttttcttaa tcaataatga agaagataat
     8641 tgattctttg cttttttact aaaatggtta ttttgttcca tcatattttt aaaaactatt
     8701 acttgttcaa gattagatat tttcaaacta tcttccatcc aatagctttt ataacttccc
     8761 aaattttcat taccataatt taattgcttg agttgagccg cagtatagtt ctttggtatt
     8821 tgattactaa tacgttcgaa gtaccaatta actgaatttt gcattgctgt atttaaatct
     8881 tgttccttat tccaagactc gaaaagataa tgtttatgat tccatgacat acgtgaattt
     8941 ttatcactta taatatgacg gtcaagtcca aacagtgcta aataaatttt gtaagttgaa
     9001 tcaggagaat atctttttct actttctttt tcattataaa tatagtattt gtctttcttc
     9061 atgctgtaca taacgaaaga tccactattt gaaccaaaat ttttactttc atctaaaatt
     9121 tggtaatcgc tttgtaaggg ctttttataa ttataatcag ttaaggattg ccccattaaa
     9181 aactggcttt gaattatcat gataaaaaaa gtaaaaatac aaataaaaat tagaattaat
     9241 tttgactgct ttttcagatc ggcttctttt atattaatta atctattttt gagtaatgat
     9301 tttttaccat taaatgaatg gcttaatata tttttgttga aaaatgaggt ttttaatacg
     9361 gagtccataa tagattccgc ataagtttta aattcatttt tgttaatatt attaaggaca
     9421 aatctatcgg cttctacttc attgtcatga attatctttc tttttacaat atgtactaat
     9481 ggattgtaac tcataataat agagaagata ttaaagataa ttaaatgtaa agtatctcta
     9541 tttttagcat gagcatattc atgcagtatt atatatttta gtcttttatc aattacactt
     9601 ttaaaatatg aactaggaat caaaataata tatttcccat accaaaaagt tattggagat
     9661 tgaatagcct ctgcttttcg aatcacaata ttttttttat attgatggtt gaaaagtatc
     9721 gtatctattt tatttttttc attttcgttt agataaagtg actgtttctt taaatattta
     9781 agatataata aggctttcaa aaatttaaaa cttaaaataa taactaaaac tatccaaata
     9841 actgtgcaga tattatcaat tgaatcccaa ttaaacttat ggatatctgt tgcgaactct
     9901 tgaacaggtt tggtggtaat tatgttatgg ttcaagtcgt gtgacttact ttcaactgtg
     9961 ggcgcttgat tattcacatt attaaatttt ataaaagaga atttaattgg gataaaagga
    10021 attaatccag caagcacagt tagataccaa actttataat ttaaactata attaaaatag
    10081 cgttttaata tgtacctaaa aaatactaac aatagaaata taaaacaaaa gcttactaca
    10141 ctcattatta gtaatttagc cattttgaca ccttctttca aatatttata ataaacaatt
    10201 gacatcaata ttacaattgt aatattattg ttttgtaaaa attacaactg taatatcgga
    10261 gggtttattt tgaaaaagtt aatattttta attgtaatgg ctttagtttt aagtgcatgt
    10321 aattcaaaca gttcacatgc caaagagtta aatgatttag aaaaaaaata taatgctcat
    10381 attggtgttt atgctttaga tactaaaagt ggtaaggaag taaaatttaa ttcagataag
    10441 agatttgcct atgcttcgac ttcaaaagcg ataaatagtg ctattttgtt agaacaagta
    10501 ccttataata agttaaataa aaaagtacat attaacaaag atgatatagt tgcttattct
    10561 cctattttag aaaaatatgt aggaaaagac atcactttaa aagaacttat tgaggcttca
    10621 atgacatata gtgataatac agcaaacaat aaaattataa aagaaatcgg tggaatcaaa
    10681 aaagttaaac aacgtctaaa agaactagga gataaagtaa caaatccagt tagatatgag
    10741 atagaattaa attactattc gccaaagagc aaaaaagata cttcaacgcc tgctgctttc
    10801 ggcaagactt taaataaact tatcgcaaat ggaaaattaa gcaaaaaaaa taaaaatttc
    10861 ttacttgatt taatgtttaa taataaaaac ggagacactt taattaaaga tggtgttcca
    10921 aaagactata aggttgctga taaaagtggt caagcaataa catatgcttc tagaaatgat
    10981 gttgcttttg tttatcctaa gggccaatct gaacctattg ttttagtcat ttttacgaat
    11041 aaagacaata aaagtgataa gccaaatgat aagttgataa gtgaaaccgc caagagtgta
    11101 atgaaggaat tttaatattc taaatgcata ataaatactg ataacatctt atagtttgta
    11161 ttatattttc tattatcgtt gacatgtata attttgatat caaaacctga ttttcccttt
    11221 attattttcg agatttattt tcttaattct ctttaacaaa ctagaaatat tgtatataca
    11281 aaaaatcata aataatagat gaatagttta attataggtg ttcatcaatc gaaaaagcaa
    11341 cgtatcttat ttaaagtgcg ttgctttttt ctcatttata aggttaaata attctcatat
    11401 atcaagcaaa gtgacataat tgttgaattt atagtaactg aaacgtatga ttagggtgta
    11461 tattaattat gagatggaaa tcaatgattg ttggctatgc gagagtatca tcgaacgatc
    11521 aaaatttaga aagacaactt gaaaatttaa agacgttttg tgctgaaaaa atatttacag
    11581 aaaaacagtc tgggaaatct attgaaaata gaccagtact tcaagaagca cttaactttt
    11641 tgaggatggg agatcggttt gtagtagaat ccattgattg tttaggtcgt aattatgatg
    11701 aagtggttgg caatccatta ctggataagt ttatgaaaga tttaattatt caaatattag
    11761 caatggtttc agaacaagag agaaatgaaa gtaaacgtcg acaagcgcaa ggaattcaag
    11821 ttgcgaagga aaaaggcgta tataaagggc gccccttact ttattcacca aatgctaaag
    11881 atccacagaa acgtattatt tatcatcgcg ttgtagaaat gttagaagaa ggccaatcaa
    11941 ttagtaaaat tgcgaaagaa gtaaatataa caaggcagac gatttacaga attaaaaacg
    12001 ataatgattt gatttaataa actttgtttc aatgcaactg agagcttctc acagcgtctc
    12061 aaaacagatg attataatct attatgagtt tttaataata agacaagaaa agagagcgta
    12121 aatatgctct ctctttttct cattaacgaa cgtttataac gcaatcatga tgagagtatt
    12181 aatacagtta attatttgaa atactttagt ttatataatg ttgaattata ggtagtgaaa
    12241 ttgtatttat tatacattgt catatcgttg tttaatgata gttaatttaa ggataataga
    12301 attaatatta tatatagatg aacaaaacaa gcaacagagc agaaaaaaca cttttagatt
    12361 atttttactc attctctatt ttatttattt ttgctataat aaataaagaa tattaaatgg
    12421 aggtgttttt atgaaaaaga aatttgtttc tagttgtatt gctagtacaa tcttattcgg
    12481 cactttatta ggtgtaactt ataaagctga agctgcaaca gtacatgtag ctggtggtgt
    12541 ttggagccat ggtattggaa aacattacgt atggtcttat tatagtcaca ataaaagaaa
    12601 tcatggttca acagcagtag ggaaatattc atcttttagt ggtgttgctc gacctggtgt
    12661 tcaatctaag gcatctgctc caaaggcttg gggtggaaac aaaacatttt atagtcttca
    12721 ctaattacat atattaatta aacttaattc tgtctattct cttgaaagag gcaatatgaa
    12781 aaaattcaaa ttatttttag attttagtac tttattatta atttcagggc tattattttt
    12841 atttttcttc aaagaaaatg aagaaattat acctgaaagt tccaatattt taacaatctc
    12901 taattgggat aaatctaaca gtaaatcaaa agtgttagat gtcattgaat caggcgccaa
    12961 aaatcaaaat atacaaataa ttaaatccgt taaagatttt gataataaaa aagaattttt
    13021 tgttttcaac tcaaaacgaa ataattctga ctttatacgt aataaaacat cacttttaac
    13081 tccatcagat ttattaaaca gagagataaa aggaaagtat tatattattg gtgaacattt
    13141 caatgtagaa gagcttacga gtgaattaaa aaaagctggt ttaacatctg aagttgaata
    13201 cataaataga aacatattat tttttgaatt agtcatagat aatgatttat tagtgccttt
    13261 catattctta ggcgtattat atcttttgta cttcttatat gacagaggat ataatttgaa
    13321 attttatgct attcaaaagc tacatggctt ttcaactaca cgcattattt ttcataatat
    13381 tcatataaaa atcatttatt ggctagtact taccgctatt ttctttattg ctaatatatt
    13441 aatcattcat atagccaatt tagaattgga tttcttaatg tttattcgta gatttatcgt
    13501 gttgcttttt gtttttgctt gtattactac attgctgtgg ctgatttcgt atagtcttct
    13561 tttgaagtta agtattccat taatcttaaa agggaaaaaa ggatataagt tttcaatatt
    13621 tatgggtacc ttcaccaaat gtatcatggt gctaatacta tcttttttac tggcacaaaa
    13681 tttaaatgct tatacgaagt taaagaatat atatgactct gaaaaaatct ggcaaaagtt
    13741 agataattac tatacattag agatttctcc taatattaga aattcagaag aaaaacaaat
    13801 tttagaaact aatatataca atttaattaa gaaaagcgaa caacttggtg gattgctttt
    13861 aaagaataat aatatagcca atcccgataa aaacaattac attcctgaaa atggcaatgt
    13921 cttttttatc aataacaatt ttctgaattt ctataaaaat ataaatcatg attttaaaat
    13981 gattgacaat cattcggata aaataaacgt gtttattcct ccaaggttac aatatcaaaa
    14041 atctgaaatt caaaaaaatc accaaggatg gattgacttt caaaagcaac aaaacaaaaa
    14101 agtagatgtg caagtactgt caaaaaacgt atctgttttt tcttttgatc gcacaactaa
    14161 tttgaaattt gggtatctag attctccaat agtaatgttg ttgacacttg acgatttaac
    14221 aggagatttt tatttagctg ctgtttctca aggtggatat ctatttaaag atttagatac
    14281 acttaaacag ttgcttaaag ataatcacct agaagaagaa attagcggta taactaatta
    14341 caaggattct gtgttaaatg aattaaatga aacgaaaaca aaaatgataa taacaatagt
    14401 tactattatt attaacgttt tcattctttt gatagctact gtatttgaaa caattcaata
    14461 ttttagctgg aataaaaagc aactattatt aagaaaaatt catggttatt cattattcag
    14521 cagtaatgta cgttatttaa caatttctat cttactttct attatgttag cttacactac
    14581 gcatatttta tttggttcaa agatattact attcataata atgtctattg ctattattca
    14641 acatttactt caaattgctt atattaaata tcttgaaaaa tactttaaag atttaatgag
    14701 ggagatttaa acaatgaaaa gaactttaat tattgtaaca attgtactat taatcatcat
    14761 acttagtctg ttattggtta gaaatgagca tttagatcgt tttaacccac tgttaaaaga
    14821 aaaagtatct tatgccaaag ttccaaaaga tacccaggac tatagaaata taactgtata
    14881 ctctaaaaat ggagaaaaaa agagttataa attggatttt ttaggttatg atcctacaaa
    14941 agaatatgtg aaagtaaatc ataaagggaa atatgtgcgt tcgatagaat acattacaaa
    15001 agatattcct agctttttaa aatgaggtga ccgatagtga taaaacttga aaatgttttt
    15061 gtaaaaaaag gtaataaaaa cattttagac ggatgtaact ttaattttga aaaaggaaaa
    15121 tcatatgctt tagttggaga aagtggcgct ggaaaatcta ctttacttaa cataatcgct
    15181 gggttcgaag atgtatcaca aggaagcata tatattgaag ataagttact aaaaaagaaa
    15241 gtcgattttt atagatatac gttagggtat ttgtttcaaa attttgcttt acttgaaaat
    15301 caaacaatca gtcaaaattt agatttagcc ctaaagttca aaaagaataa aaaagataat
    15361 atgaacttaa agaaagaagt attaaaaaag gtcggcctag atttagatat caagagaatt
    15421 gttagttctc taagcggtgg tgaacaacaa agagtagcat tggcaagatt aatattaaaa
    15481 gatccgaaaa tcattttagc tgatgaacct actgggtcac tagatacgaa aaatggaaaa
    15541 atagttattg atttattatt gaagctactt gatgaaaata aaactatgat tgtcgtaacg
    15601 catgatttag agcttgcgaa acgatttgat gtcatagtca atatttctga gcttagaagt
    15661 taagaaatat tgataggtat agccatacat agagaaaaaa caatatgaaa tatgattagt
    15721 cattactttt gagtttttta atttaaggac tggattttcc agtccttttt tatgatgaca
    15781 aaaaacaagc ctcgcagagc acacgttttt aatgacttat ttggttttta ataagtctag
    15841 tatgttaaaa cttttctgtg tttaggtgtt ataatcatat gcagtggaag ttgatttatt
    15901 atgtcttatt caattattcg agttgttaaa gtgaaatcaa aaacaaatac aagaggtatt
    15961 caaagacata ttcaaagaga aaataaaaat tatgaaaata tagatattga tttaagtaag
    16021 tcatatttaa actatgattt agtcaatgat actaagtttg attttaataa aaaaattgat
    16081 gagaaaatcg aaaaaaatta taaagggaaa cgcaaaatta gaacagatgc cattaaacat
    16141 attgatggat taattacatc agataatgtg ttttttaatc aattatctga agaagagaca
    16201 aaatagtttt ttaagcatgc taaagcgttc ttggaagaag aatacggtaa agaaaatctt
    16261 ttatatgcga cagtacatat ggatgagata acaccacata tgcattatgg cgtagttcct
    16321 attactaaag atggacgttt aagtgcgaaa gaagttgtag gtaataaaaa agcattaacc
    16381 gaattccaag atagattcaa tacgtatatt aataagcaag gctatgattt aaaacgagga
    16441 atttctagac aacttacaaa agaaaaacat gatcaagtta gccgttataa acaaaaaaca
    16501 gaatatcata aacaaatgca tatgcgctag aagcaaatag aggattattt aaagcaagaa
    16561 aatgataaat tgatacaaaa ctaccaaaaa tcattagata cgcttaaaaa gcttctgagt
    16621 gtcatgtatg aaattaaaac taaaaatgta ggtggatggt ttcataaaga gaagcaagaa
    16681 acaggcaata ttgtaattac taaaactgat tttgaaaaat acactaaaca aattaaagca
    16741 gcacagatga tattagatga ttatgaatgt attaaaagtg ggaagtcatt aaaaaaagca
    16801 gagaaacaaa atgaaagttt agttaatgaa ttgactagtg tccatatgga aaatgaaaag
    16861 ctggttgaag aatttaatga tttagcacaa cgttataatt atttgttgtc agagaatgaa
    16921 aagaaagata aagaactaaa ttatacgctt aagttattca atcaagtttt taaaatcatt
    16981 aaaagtatga tgaaagaaga gcgttatcat acactaataa atcatattga taatcattta
    17041 gacaattcta aaatacgtga agtaatgacg atagataaca atgatgaaca gttctttaag
    17101 aagaaatatc aagcacaaga acgagaaatc atttttaaag aagatagaga agatggttat
    17161 acattataaa aatagatatt taaatgcatt tgtttgaggt taattatttt ttaggatgaa
    17221 aaataggtag cccccctcga actttttaat atatttttat aaatcttttt aaaaaccttt
    17281 ttaggggctt gttcagccct agagcaacaa gggatttcaa tgcctaaagg agtgtttttg
    17341 ctacataaaa ggagtgtttt tgccacataa aaggagtgtt tttgccacat aaaaggagtg
    17401 tttttgccac ataaaaggag tgttttaaaa agttgtactc cttttatggt ttgacattga
    17461 taataaagta gtttattgtg aataaaagtt ttcaaatggg agtgtatatt caaacgatac
    17521 tcctttaggt tcgtaataaa gggggctgta tcatgacagg agagacagtt gtatataaaa
    17581 atgaaatgaa tttagttcca ttaaggcgat ttacagctac tgaaattaat ttattttttg
    17641 cgatgtgtaa taaattaaaa gagcaagata ctaatacatt acgtttgtct tttgatgaat
    17701 taaaaaaatt aagtaattat agtccagaaa cacgtaatat taatagattt gctaatgatt
    17761 tagataatgt gtataaaaag atgttgaatt taaccattag atatgaagat gatgatgtaa
    17821 tagaaagatt cgttttattc aatcattata gaatccataa gcgagaacaa tatctagaaa
    17881 tatcaacttc ttcaaattta aaacacatat tgaattcaat tactaataat tttacaaaat
    17941 ttgaattaaa agaaatgact aggcttaaat ctacatattc taaaaatatg tttagattac
    18001 ttaaacaata caaacataca ggctatttaa aaattcacat cgatgatttt aaaaatcgtt
    18061 tagatatacc taaatcttat cgtatgactg atattaacaa aaatgttttt aaacctatta
    18121 ttattgaatt aggttctata tttaataatc ttactatcaa taaaatcaaa gcgaaaaaag
    18181 ggcgtaaaat tgaatggata gagttcacat ttgacgctga gaaacgcatt cataacaaac
    18241 gacaacctca aatgtccaag atagataaat caagacaata tgtgaggcgt gaaaagacgc
    18301 ctaaatggtt agaagaacgg tcatatgaaa agcaacctca aaaagattac gacccacaat
    18361 tagagaaaga acgagaggat tttttaaaac aacttgaact gaattgggaa taacgcaact
    18421 tttcgttgcg agttggttaa ctaaaagtat cgtgactttt caattatttt aattatagtt
    18481 tgagttaagg agtgatttta tgaaattagc tgaagctata aaagaacaga gagaattaaa
    18541 aggatggtct caagaggaat tagccaatat attaaaggtt tccagacaaa gtgtttctaa
    18601 atgggaaagt gccaaaaact atccttcctt agatattttg attgctatga gcgatttatt
    18661 cggaatctct ttagagcatt taattaaagg agatgcacgt tttaaaaaag ttattttaga
    18721 gggaaattat agagagagta acagggtacc ttccatagtt gattttcttt atgatttttg
    18781 gtggcttttc tttcctgttg ccggattttt agtttgggcc attcattcgt tcatgggttg
    18841 attttaaaat caaaatttaa tgcacatcag gcaatatgaa aaaggaaagt atttttacga
    18901 caccttgaaa tgtattgata agaatagaag agtttacaaa aggcaatatg aaatatatac
    18961 taaaagtaac aagaatttcg tttgtaaacg caccaaaccc cgaactattc gccgtagttc
    19021 ggggtttttt ggtgaattgg ctttaatcgt ctatattatt ttttatcacg tttatggagc
    19081 taataaccaa ataacgtaac gagacaacca ctgattgccg ttgtcatgat gtgaacaaga
    19141 atttcattca taaatcgcac ctcctctcta cgccgaattg acatctgaga gatagacgac
    19201 cttcacatta taacaaatct ctccttccat gaaataacat gaatattaat aaatgttgtt
    19261 atatattaaa gataaataaa tataagggtg ggattgataa tgtttggcga tcaaagacaa
    19321 gaagctacaa aatatgtcat taaagaaggt tatcaagata tttatttcct caacaaaaac
    19381 ggggaatggt attatttcga agtaagaagt gtctggcgtg gcaaacatat tattagagtt
    19441 aaagatggtt tgttaggttg gagaaaagaa atagtaactg aataaagata caaaatactt
    19501 gccaatgcaa aagaatgaaa acgcgtcaaa tcaacgatgt ataaaagatg cataaaagat
    19561 aatgaaagta aaaagccata aatgccgtca tataggcatt tatggctttt tgtttggtta
    19621 atataatcga tgattatcag aagttcaatt cacataaaaa agcacggcta atttatgaac
    19681 ttgtcgtacc tttttaatta aaattagtta ccaaatagac gactccaaaa ccccttttta
    19741 gcttccgttt cttcactctt ttcttctata tcactatcat tgtcatttgg attagctgaa
    19801 acgtcttctc tttgtgcttc ttcaccttgt gtactttcgt cgctttgact tccagatata
    19861 tccttatatt gaatctctgt ttctttagtt tcttcctgat ctcggttaat atttacagga
    19921 ctagtagtat atgttttttc ttgtgcatca acgttttgtc tagcgttagt agatgtatca
    19981 aagggataat taaggtgttt ttctttttct aattgatttt ctaatttttg aatcttttta
    20041 ttactctcta atgccagaac ttgctgattc tcaagcaatt ttgatctttc ttgcaactct
    20101 tttctgtaaa attcaattgt tgtttcatga cgactttctt gtttttcaat ttgattattt
    20161 aaagtattaa tctgattttt aagtatttct actatttgag catcgctttt agattcaaaa
    20221 ttaatattat ccgactcttt tttttgtttg tcttcagtag cactttcaaa accatatttc
    20281 tttttatttt catttactct ttgaatgatt ttttctatat cggtatcttc tttaataaac
    20341 gaagtgtttt cctgttttat tgtctctata ttcaatctct taatattatt aaaaatcgtt
    20401 tgcttactaa cccctaattc ttcactcaac ctttttacac ttttcatatc atcaaccctt
    20461 tataaaatgt ttataaaccc ttagtaaaat attataagct tataacgatt aataataaag
    20521 taatcgacaa ataaaaatat aaattcgcca acctttttat caagggtttg taaagggttt
    20581 atggtgttta tcaaaggttt ataaacctat attttccctt ttttaagttt
//
