LOCUS       NZ_MH785244            17257 bp    DNA     circular CON 21-JUL-2023
DEFINITION  Staphylococcus aureus strain tu1 plasmid pAvX, complete sequence.
ACCESSION   NZ_MH785244
VERSION     NZ_MH785244.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN09846914
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 17257)
  AUTHORS   Bukowski,M., Piwowarczyk,R., Madry,A., Zagorski-Przybylo,R.,
            Hydzik,M. and Wladyka,B.
  TITLE     Prevalence of Antibiotic and Heavy Metal Resistance Determinants and
            Virulence-Related Genetic Elements in Plasmids of Staphylococcus
            aureus
  JOURNAL   Front Microbiol 10, 805 (2019)
  REMARK    DOI: 10.3389/fmicb.2019.00805
REFERENCE   2  (bases 1 to 17257)
  AUTHORS   Bukowski,M., Hydzik,M., Sabat,A.J. and Wladyka,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-AUG-2018) Faculty of Biochemistry, Biophysics and
            Biotechnology, Department of Analytical Biochemistry, Jagiellonian
            University, Gronostajowa 7, Krakow, malopolskie 30-387, Poland
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/21/2023 01:13:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 22
            CDSs (total)                      :: 22
            Genes (coding)                    :: 18
            CDSs (with protein)               :: 18
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 4
            CDSs (without protein)            :: 4
            Pseudo Genes (ambiguous residues) :: 0 of 4
            Pseudo Genes (frameshifted)       :: 1 of 4
            Pseudo Genes (incomplete)         :: 4 of 4
            Pseudo Genes (internal stop)      :: 1 of 4
            Pseudo Genes (multiple problems)  :: 1 of 4
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MH785244.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..17257
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="tu1"
                     /isolation_source="conjunctivitis"
                     /host="Farmed turkey"
                     /db_xref="taxon:1280"
                     /plasmid="pAvX"
                     /geo_loc_name="United Kingdom: Scotland"
     gene            complement(125..493)
                     /locus_tag="D0Y81_RS00005"
                     /old_locus_tag="D0Y81_a00105"
     CDS             complement(125..493)
                     /locus_tag="D0Y81_RS00005"
                     /old_locus_tag="D0Y81_a00105"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_041203784.1"
                     /translation="MKDFFYGDPWFTFLIYRENRRGKSKDSKLGFYLAGDKELMVSVRK
                     HFSNVYPNIEFHEADESHLDFPTKRSYFGYAKLKHNSLKQGYPIEIFQHDNLTKIVSIM
                     EPDTWLQFRFRRNYGFKL"
                     /name="hypothetical protein"
     gene            complement(1355..2929)
                     /locus_tag="D0Y81_RS00010"
                     /old_locus_tag="D0Y81_a00005"
     CDS             complement(1355..2929)
                     /locus_tag="D0Y81_RS00010"
                     /old_locus_tag="D0Y81_a00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000932174.1"
                     /translation="MLNINKIYDFILHGSIEKYKFKNSKATDLEKANFKATQPRNWRSA
                     RIAVTPNKATLIDGLGLIIASEEALVQYGHKFSHWTPNPYNYLSKEKANIADVNTYKVL
                     NRTKDNVKQINTFVLDVDEDIEYNELVQSLASAHINEGAELPNLYVKTPRGWHLYFVLD
                     TPFYAKGIEKKAIKVAEKVHSSLAHAISKYLPVDNQCVSTGYFRLPTKDNVQLFTNQYC
                     SKSYMVRWSKEYSEKHNLNQNVLYKSIANGQELTPEWVDYLLKEADVTSFGYGVGRNNA
                     MFSVALYYYSKNIDMKVAESNIYAFNQRLNQPLSHKEVERVIKSAYSGRYGGAMREHVE
                     NLLEAFTDGQIAYSNSGVSINGFWKHKKERKDRVRSHFDERKADLERYLNEHTNKQKVF
                     VKGSMSAIAKKLGMARSSLYAVFEKHINKGTIIKYTIKNGRYSETFIALKSVYIESLFE
                     MVKSIKNKKESYITAIRHLVSSERNTHSLMVQNNGLLNEIENTLTYIDRHTQYIEGNEI
                     LYERFIS"
                     /name="primase C-terminal domain-containing protein"
     gene            complement(3321..3569)
                     /locus_tag="D0Y81_RS00015"
                     /old_locus_tag="D0Y81_a00010"
     CDS             complement(3321..3569)
                     /locus_tag="D0Y81_RS00015"
                     /old_locus_tag="D0Y81_a00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632623.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_001004832.1"
                     /translation="MNENILLELCSKLKGIRKGKKYTQQEVADIIGINIWTVNRIENKK
                     LEEVKLKTILRILDLYEITLYEFIEDNKDIVNRAYNK"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(3582..4136)
                     /locus_tag="D0Y81_RS00020"
                     /old_locus_tag="D0Y81_a00015"
     CDS             complement(3582..4136)
                     /locus_tag="D0Y81_RS00020"
                     /old_locus_tag="D0Y81_a00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001062591.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001062591.1"
                     /translation="MAKIGYARVSTISQSLETQINLLKAEGCIKIFSEKVSGKKTNRSK
                     LDECLKYLREDDVLVVTKIDRLGRTTKQLINLASWLQEHNIELKILDGNFNMNSPLGKM
                     IFTVMSGFAELETDLNRERTLEGLNEAKARGRKGGRPGVTKDVKNYVMYLYNNTELSGN
                     EIARKTGVSRSTVYRIKRDFN"
                     /name="recombinase family protein"
     gene            4643..4774
                     /locus_tag="D0Y81_RS00110"
     CDS             4643..4774
                     /locus_tag="D0Y81_RS00110"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012840548.1"
                     /translation="MYIIYLKKGFIDISKEGKMAKIGYARVSTKDQNLGSVVKLEKV"
                     /name="hypothetical protein"
     gene            <4876..5379
                     /locus_tag="D0Y81_RS00025"
                     /old_locus_tag="D0Y81_a00020"
                     /pseudo=""
     CDS             <4876..5379
                     /locus_tag="D0Y81_RS00025"
                     /old_locus_tag="D0Y81_a00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /name="IS30 family transposase"
     gene            complement(<5385..>5588)
                     /locus_tag="D0Y81_RS00030"
                     /old_locus_tag="D0Y81_a00025"
                     /pseudo=""
     CDS             complement(<5385..>5588)
                     /locus_tag="D0Y81_RS00030"
                     /old_locus_tag="D0Y81_a00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622542.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /name="ABC transporter transmembrane domain-containing
                     protein"
     gene            <5726..6032
                     /locus_tag="D0Y81_RS00035"
                     /pseudo=""
     CDS             <5726..6032
                     /locus_tag="D0Y81_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622764.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(6116..6433)
                     /locus_tag="D0Y81_RS00040"
                     /old_locus_tag="D0Y81_a00030"
     CDS             complement(6116..6433)
                     /locus_tag="D0Y81_RS00040"
                     /old_locus_tag="D0Y81_a00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphostatin A"
                     /protein_id="WP_000049867.1"
                     /translation="MSKYQLINIKDNNLEFSEKYWLHILQGVWRPEKISTKPLKITFNK
                     NIFPIYICKEINEDSRRIILNNTDNTNIIIEIIIINHKKIIFNVLNKLSLGVTPKITFI
                     K"
                     /name="staphostatin A"
     gene            complement(6454..7653)
                     /locus_tag="D0Y81_RS00045"
                     /old_locus_tag="D0Y81_a00035"
     CDS             complement(6454..7653)
                     /locus_tag="D0Y81_RS00045"
                     /old_locus_tag="D0Y81_a00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366922.1"
                     /GO_function="GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="WP_001074681.1"
                     /translation="MAKKICNISTIVFVLAIGLILSLVFSLFFNNVNAEEASQKELPNQ
                     KNTKVNIDKKDIPSAVKKLAEDQYLSRVAALDKLSGEKNSSYTLGEAFKIYKFNQKSDG
                     NYYFPVLNKEGKVVYVVTISPKIANDKNTSSNSDYTINVSPFLSKILNQYENQKFTILT
                     NTKGYFVVTEDNKIKHVLKTPYSGEKNSKNTMESPKNIDLKNFKQTASVTKPIIQFENP
                     KYGVRAQYVNQLKNFKIRETQGNNGWCAGYTMSALLNATYNTDRYNAEAVMRYLHPNLQ
                     GDDFQFTGLTPQEMMKYGKSQGRDTQYLNRMPSYNEVDKLTTNNKGIAILGSRVESTDG
                     IHAGHAMAVVGNAELEGGQEVIMIWNPWDRGFMTQDAESNIIPVSNGDHYQWNSSIYGY
                     "
                     /name="C47 family peptidase"
     gene            complement(8148..>8504)
                     /locus_tag="D0Y81_RS00050"
                     /old_locus_tag="D0Y81_a00040"
                     /pseudo=""
     CDS             complement(8148..>8504)
                     /locus_tag="D0Y81_RS00050"
                     /old_locus_tag="D0Y81_a00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /name="IS30 family transposase"
     gene            complement(8846..9088)
                     /locus_tag="D0Y81_RS00055"
                     /old_locus_tag="D0Y81_a00050"
     CDS             complement(8846..9088)
                     /locus_tag="D0Y81_RS00055"
                     /old_locus_tag="D0Y81_a00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002437031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044290595.1"
                     /translation="MAGFLDNIKVVGQQKRGFLDDIDTSAVKYTENYKPMAKSSTMRVD
                     TLIKRRLSQMALDKDTSIKAISDKVLQEFLEKNNY"
                     /name="hypothetical protein"
     gene            complement(9098..9889)
                     /locus_tag="D0Y81_RS00060"
                     /old_locus_tag="D0Y81_a00055"
     CDS             complement(9098..9889)
                     /locus_tag="D0Y81_RS00060"
                     /old_locus_tag="D0Y81_a00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111526.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000111526.1"
                     /translation="MSVITIGNFKGGVGKTTVSTLLSYIGSERYDKRILLVDFDPQGNA
                     TQIMKRTYPEAIDEKQTFIDALKTGELEDSIINLSTKLSLLPADSSLANLSDIIAKTDI
                     IKKRYILKTVIDQIKKNYNFDYIFIDVPPTINSDFTNNAVYASDYIAMVFQTQQSAYES
                     SLSFVNFLRDRKKESNLPFELIGAIPVLIKKNGNIDEYILEISKKTFSNALFKNQIFQR
                     ERIKKFGAEGIRDKDVHDKRVLHMLEAIYKELIERIELIEG"
                     /name="ParA family protein"
     gene            10019..11302
                     /locus_tag="D0Y81_RS00065"
                     /old_locus_tag="D0Y81_a00095"
     CDS             10019..11302
                     /locus_tag="D0Y81_RS00065"
                     /old_locus_tag="D0Y81_a00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000083517.1"
                     /translation="MSQSLRFTKLYKFLFEDPTFKTLPAKAKLLYALISERQSLSKANA
                     KQHGIQSQFIDNEGRLFSIYTNQELMTKLNMSKPTVIKLKKQLIEFGLLEDVRLGNNQP
                     NRLYPKKPYDNYFYAYDVDEFYRLPHALFENPKYQSLAAESIIAYAIYLSRYEYSIYKN
                     HFSDENGAVYCCFSNDNMANILDVSTRKVERIKKELIVSSLMINKRASFGKSNRLYISL
                     PKASDDKEVKKCRTSYTYFSYTYSSDIDSNDMNDTYDNNIDEVHEINDSPQTNHSSHPN
                     HQHNTEDTFNDQQVEQEMLLQHLPDYVQLNLKHFSNTEIRCIKSVLNKAKASYNHHAPV
                     DERVTYEACTYAIGEALRRIKLLSRQKNENICDLEAYMMQTFKRVFVEHVLNDQQKLDD
                     TKTKTHDISQFEPKNAFQSMAKRMFLDV"
                     /name="replication initiator protein A"
     gene            11334..11567
                     /locus_tag="D0Y81_RS00070"
                     /old_locus_tag="D0Y81_a00060"
     CDS             11334..11567
                     /locus_tag="D0Y81_RS00070"
                     /old_locus_tag="D0Y81_a00060"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001002995.1"
                     /translation="MNEKEIGIAFLNHFTQVEAYLEALGVPENHIADIKPIVIQNYPYE
                     RFLFDDLGDVTNVIIPFSKVIGSNLFGNIGYK"
                     /name="hypothetical protein"
     gene            11577..11987
                     /locus_tag="D0Y81_RS00075"
                     /old_locus_tag="D0Y81_a00065"
     CDS             11577..11987
                     /locus_tag="D0Y81_RS00075"
                     /old_locus_tag="D0Y81_a00065"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000872163.1"
                     /translation="MKWSLEQNFHGNAPNLKPQKIQGCLGFLKSLGWENWNQSYQTLDI
                     GELYFSLLLDDKGHVITYMHEGGNGGGRHRIFTGKVCGAEYVRAARLTQFRLNKQKLAY
                     YKNNWYLSNKLKILFKKVNCFKLFVSYILFMF"
                     /name="hypothetical protein"
     gene            complement(12139..12813)
                     /locus_tag="D0Y81_RS00080"
                     /old_locus_tag="D0Y81_a00070"
     CDS             complement(12139..12813)
                     /locus_tag="D0Y81_RS00080"
                     /old_locus_tag="D0Y81_a00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001106066.1"
                     /translation="MNYFRYKQFNKGVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPIVYQIWKKKHKKAYYKWRIDETYIKIKGKWNYLYRAIDAEGHTLDIWL
                     RKKRDHQSAYAFIKRLIKQFGKPQMIITDQAPSTKVAMTKIVKVFKLNPNCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSLNTAKNTLKGIECIYGLYKKNRRSLQIYGFSPCYEISHML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(13392..14075)
                     /locus_tag="D0Y81_RS00085"
                     /old_locus_tag="D0Y81_a00075"
     CDS             complement(13392..14075)
                     /locus_tag="D0Y81_RS00085"
                     /old_locus_tag="D0Y81_a00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019168208.1"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="WP_000277644.1"
                     /translation="MYKNLNNIHQSHYLALIYIILLIIIPRYAILPFSNKLNINYDIIN
                     EWYFFVITTILMIYAIKIFKVKLQKDWLNIKNKKIGVFLTGIVGFFLILLLNVILILII
                     NQGRPVKSVNQNAIENISFLSQFFAPLLIVIIGPILEELLFRVYILEVLKNKIKLLPAI
                     LISISSFTVIHMHSLTEDWKTLIPYFSIGIVTVFIYLKKHNFYYILSIHVLNNLVAQIA
                     IWFLQ"
                     /name="type II CAAX endopeptidase family protein"
     gene            complement(14250..14588)
                     /locus_tag="D0Y81_RS00090"
                     /old_locus_tag="D0Y81_a00080"
     CDS             complement(14250..14588)
                     /locus_tag="D0Y81_RS00090"
                     /old_locus_tag="D0Y81_a00080"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436882.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003723 - RNA binding [Evidence IEA]; GO:0004521 - RNA
                     endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_001022435.1"
                     /translation="MNIKQFDILYIDLNPTRGREKHNVRPCLVINNQMSIDGTNFVWVL
                     PITTRGLRYPTDIQLKTKKGLVSGVIDTVQIRALDLKARQYNYKDELQDNLKNDILKAI
                     KTYLKPTL"
                     /name="type II toxin-antitoxin system PemK/MazF family
                     toxin"
     gene            complement(14585..14968)
                     /locus_tag="D0Y81_RS00095"
                     /old_locus_tag="D0Y81_a00100"
     CDS             complement(14585..14968)
                     /locus_tag="D0Y81_RS00095"
                     /old_locus_tag="D0Y81_a00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_254231371.1"
                     /translation="MQSRIVKAMFLIFINYSTSYVFTLVTTFVMMNKRGLIIMAKSLKD
                     LNKTSERVFKNGNSKAISLSKKTIRLANFDIGDTVEVQKMNGGLFITKKKESIEDRIKN
                     FFQSGGKYTELEVDWEERVGREI"
                     /name="hypothetical protein"
     gene            15425..16234
                     /locus_tag="D0Y81_RS00100"
                     /old_locus_tag="D0Y81_a00085"
     CDS             15425..16234
                     /locus_tag="D0Y81_RS00100"
                     /old_locus_tag="D0Y81_a00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002491360.1"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_001106667.1"
                     /translation="MNYIKYIHSVDGTTLYVKVNENVNSSANIIICHGLAEHLDRYDEI
                     SNYLQEKNFNIIRFDQRGHGRSGGKRTFYSNVNEIVEDLDAVINFTKEHYKGNIYLIGH
                     SMGGYGSVLYSTKNPGKINGLIISGAVTRYNQKTFGDIDDTIDRNKYINYEIGEGVCSD
                     TFELEKYRLDALTEKKVSYGLIYTVLEGVKGLVENAQYFDDNILILHGKDDGLVHYSDS
                     LDFYKNISSSKKELHIYDGLQHEIFNERKKNKEIFSEIANWINNDLT"
                     /name="alpha/beta hydrolase"
     gene            16347..17078
                     /locus_tag="D0Y81_RS00105"
                     /old_locus_tag="D0Y81_a00090"
     CDS             16347..17078
                     /locus_tag="D0Y81_RS00105"
                     /old_locus_tag="D0Y81_a00090"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019168209.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_000753929.1"
                     /translation="MKKTTIYFVLYFIISALGFGMLKKLGIEYNSLEIAVYALPMMIIL
                     SIFVYSIALNPYQKRKSSPIIHVKSLEYVVPLVILCDILIILELLYTGNFRPILVAQLF
                     LTFLIGFSEEFFFRKYIIEHILTKYKSKLLALITSSILFGLLHMANTFGGLTIENAASQ
                     SMSATGVGLLYGLIYIFTKKIWMLVLLHMNVDFALFSSVINQSYLQAVPAFIVDIILIF
                     TVLKIIMYILKSIKSKNNKFL"
                     /name="CPBP family intramembrane glutamic endopeptidase"
     Typing          complement(1431..2929)
                     /name="rep_cluster_155"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          10020..10750
                     /name="rep_cluster_2439"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="97.951"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tatcaaaagc aacatcacta tacgtaaaac gtttgttggt ttctttccaa atctcctttt
       61 cataattatc ccgatcttta aatttttgct ctctaatatc ttcatcagtc ttttttatag
      121 cttttcataa cttaaaaccg taatttcttc taaatctaaa ttgtaaccat gtatcaggtt
      181 ccataatact aactatctta gttaaattat catgttgaaa tatttctata ggataaccct
      241 gttttaaaga attatgtttt aacttagcat aaccaaaata tgatctttta gtaggaaaat
      301 ctaaatgact ttcatctgct tcatgaaatt ctatatttgg ataaacattg ctaaaatgtt
      361 ttctaactga aaccattaac tctttatccc ctgctaaata aaaacctaat ttgctatctt
      421 tactttttcc tcgtctattt tctctataga ttaaaaaagt aaaccaagga tctccataaa
      481 aaaaatcttt caaaaatatt tcttctagtc gaatgaatat ttttcaataa tttaaaaatt
      541 ttatcagatt taggaaaatc tccctcataa gttaatattc tataatattc catatttttc
      601 tgtattttaa ttattttcat aatatatcgc aacaacatag aaaatattat taatacaatt
      661 gcaaaaattg caccagcgat cagtgatgct cgcgctgtga aaaatatgag tagtgaaagg
      721 ataaggatat aggatatgaa taaggagagt tgtctaagaa gtttagacgt catatgtgga
      781 tacctcccgt ttgtatttgg ttgtcaaggt acagtggata tgtcgccccc gcatttaaca
      841 aataaaaaac aaagtcttct ccagttacga ttaattaaga tgatgatatt attctatgaa
      901 taatgtaatc ttatttaatc taacaggaaa tagtcacgaa aaataccggg ttttatatcc
      961 ttaattacat ttcaccttaa aaagactata aaaacaatat ttaatttgta tatcatgtta
     1021 tgtgttatgt agttcattat ggtatggatt atgtaatgaa tttaatcaaa gcataatcta
     1081 attatattaa tcttaataca tagtataata cgtcatatat tcacaccata atcaaacgca
     1141 atatacaccc ataatatata attgttaatg gggagagatc tccattttgt taaaatattt
     1201 taggtaattt ttaatttttt ggcgcctgct aattttaatt agtaggcgtt tttctattat
     1261 tctacataac tacttaacta ctcacttata tatattattt acagaaacgc acaaacaccc
     1321 tgatatatgt aatggcacat cggacaatta aaatttaact aataaaccgt tcatatagaa
     1381 tttcattacc ttctatatat tgagtgtgcc gatctatata agtgagtgta ttttctattt
     1441 cattcaacaa accgttattt tgtaccatta aactatgtgt atttctttca ctgcttacaa
     1501 ggtgtcttat agccgttata tagctttctt ttttgttttt aatactttta accatctcaa
     1561 ataaactttc aatatacacg ctttttaaag caatgaaagt ttctgaatat ctaccgtttt
     1621 taattgtgta tttgataata gttcctttgt ttatatgctt ttcaaaaact gcatataaag
     1681 atgatctagc cattcctaac tttttagcaa tagcactcat tgagccttta acaaacactt
     1741 tctgcttatt tgtatgttca tttaaatatc tttctaaatc ggctttacgt tcgtcaaaat
     1801 ggcttctaac acgatcttta cgctcttttt tatgtttcca aaagccattg atacttacac
     1861 cactattgct atatgcaatt tggccatcag taaaagcttc taaaaggttt tctacatgtt
     1921 cacgcattgc gccaccataa cgaccgctat aagcactttt aattactctt tcaacttctt
     1981 tatgtgataa aggctgattt aagcgctgat taaaagcata gatattactt tctgctactt
     2041 tcatatctat atttttagaa taataatata acgctactga aaacattgcg ttatttctac
     2101 caacgccata tccaaatgaa gtaacatctg cttcttttaa caaataatca acccattcag
     2161 gcgttaattc ttggccattg gctatactct tataaagtac gttctgattt aaattgtgct
     2221 tttctgaata ctctttactc cagcgcacca tataagattt tgaacagtat tgatttgtaa
     2281 ataactgaac attatctttt gtaggcaatc tgaaatagcc agtagataca cattgattat
     2341 cgactggtaa atatttagaa attgcatgtg ctaagctact atgtactttt tcagctactt
     2401 ttatcgcttt cttttctata cctttagcat agaacggtgt atctaataca aaatataaat
     2461 gccaacctct aggcgtcttt acatacaaat taggcaattc agcgccttca ttgatatgcg
     2521 ctgaagctaa gctttgaact aattcattat attcaatatc ttcatcaaca tctaaaacaa
     2581 atgtattgat ttgttttaca ttatcttttg ttctgtttaa cactttatac gtattaacat
     2641 ctgctatatt agctttttcc ttacttaaat aattatatgg attaggcgtc caatggctaa
     2701 atttatgacc atattgaact aaagcttctt ctgaagcaat aattaagcct aaaccgtcta
     2761 ttaatgtagc tttattaggt gtgacagcaa tacgtgctga tctccaattt cggggttgtg
     2821 tagccttaaa attagctttt tctaaatctg tagctttaga atttttaaac ttatactttt
     2881 ctatgcttcc atgtaatata aaatcataaa ttttattaat atttagcatt gtctgcacct
     2941 cctaaacaaa aaagactgat aacacttgta agcgttacca gtccttgttt aggcgtccat
     3001 atacatttaa agtagtcgag tagcgaagta gaaaagtaga aaagtagcgt ctttttcttt
     3061 actttcttct ctcatgcccc tataatttag gtatacaaaa taatttaaaa atacctaaat
     3121 cataaaggta tggaagaaga cccgaaaacc gtttgtatac gttagtgagg taacgtttca
     3181 agcgctagaa gttaaaaatg ttggtagcaa ttttaacttt gcacgtggtc ttttttcata
     3241 tctttttttg attaattcta gtataaactt ctatattgac gattgcaata attttggtac
     3301 atttgcaaat aaattaaatg ttacttgtta tatgctctat ttactatatc tttattatct
     3361 tctataaatt cataaagtgt gatttcatat aaatcaagta tacgtaaaat tgttttaagt
     3421 ttaacttctt ctaatttttt attttcaatt ctgttcacag tccatatatt aattcctatt
     3481 atgtcagcaa cttcttgttg tgtgtacttc ttacccttcc ttatcccttt aagtttagaa
     3541 cataattcta ataatatatt ttcattcatc ttttttcccc cctaattaaa atcacgtttg
     3601 atacgatata ctgttgatct acttacacct gtttttctcg caatttcatt acctgataac
     3661 tctgtattat tgtatagata cataacatag ttctttacgt ctttcgtaac acctggtcgc
     3721 ccgccttttc ttcctctagc tttcgcttcg tttaaacctt caagagttct ttctctattt
     3781 aaatctgttt ccagttctgc aaagccactc attacagtaa atatcatttt tcctagtggg
     3841 ctattcatat taaaatttcc atctaatatt tttaattcta tattgtgttc ctgtagccaa
     3901 cttgctaaat ttattaattg tttagttgtg cgtcctaatc tatcaatttt agtcacaact
     3961 aatacatcat cttcccttaa atattttaag cactcatcta atttacttct atttgttttc
     4021 ttgccactta ctttttcaga aaatatttta atacaacctt cagcctttaa taagttaatt
     4081 tgtgtttcta agctttgact gattgttgaa actcttgcat agcctatttt agccaaaata
     4141 tcgcctactt cctttataaa tagctttaat atgaacgatt gtgtgtgcgt ttacgtataa
     4201 tgggcttcaa aatatttttt cgcggcgtct gagggcttct ctcagcttgg tcaaaaaccc
     4261 tttttacctt taattttgac actttgattt taacacatat tttgaccagg cacgaatata
     4321 gttaaaggct tatagaattt attcagttct acaagccttt aatccttaca aatagcactt
     4381 attcaagcat attttttatt attttatttt acttattgaa atatattatt ttctaatgtc
     4441 ataccctggt caaaaccgat cggttttgac taggttatgt tagaaacagt actttttgac
     4501 tgtctataaa acggaggttt atagacaaca gtaactaaaa tatattataa agtacgaaga
     4561 aggatagtaa atcccttata tttaaggtgt ttattatcct ttttatattt aatacaatgt
     4621 ctatttactt atctataaat caatgtatat aatatactta aaaaaaggtt ttatagacat
     4681 tagtaaggag gggaaaatgg ctaaaatcgg ttatgctaga gtttcaacta aagatcaaaa
     4741 cttaggttct gttgtaaagt tagaaaaagt atagctaatc atcattttat catgtcagtg
     4801 ttcgtttaac tagctaacac tgaaatgata aaaaaggaaa ttagatgttt ttctaacttt
     4861 gcaacagaac cagaatttcc tttattcaat aaggagtttg ggcatcttga aagagatact
     4921 attgttggtc gtcgtcatgg tagtgcaatc attactttgg tagaaagagt ctccaagatg
     4981 attatcacct tgcgaccctt aggtcgtaag gcaaccgata tagaaaatgc tctgcactca
     5041 atgttttcag ctttaccttc tcatatattt aaatcaatta cttttgattg tggtaaggag
     5101 ttttcaaact ggaaaacaat atgcaactgt catgatatat ctatattttt tgctgatcca
     5161 ggcacgccat cacagagagg cttaaatgaa cattctaacg gaatacttag acgcagtgga
     5221 ttagataaag aactagattt caatttagta acagacaatc atatcatcag tgttgctcaa
     5281 aaaatcaatc atcgtcctag aaaatcttta ggttatagaa caccattgga agtatttatg
     5341 agtttcatcg aagatgataa actgtccagc ttaatttgat aatctaaaat cttaaaaaat
     5401 aaaggaataa taacaaaagt acacaaagtc attttccaat ccaatataaa aagcataatt
     5461 atggaaccaa taattgttaa tacattaggt aaagtaatgg gaaccttatg tgatataaaa
     5521 gtatttataa cctttgtatc gtctactatc ctacttaata attctccact ttcactcgaa
     5581 tcaaaaaaat aactatgctc aaaaaaggta tgtttaatga acctctattt attttgttta
     5641 ctagctctcc cgtaaataat ggtagcgaat ttactttttc agtattaatc attatgctat
     5701 gtatctcatt tagaaatcac cccaaaggtt atgcaataag acgaaattta ttaatcgttt
     5761 gaattctgtt agtagaaagt ctataagtaa agatatctag aaagttgtta actattatag
     5821 gaagaatcaa agaattctaa gaaatacaat ttatcatcca gtatttaata atagatttat
     5881 ggaaggaatt aataataaga taaagttaat tgaacgaatt tcttttggct acagaaattt
     5941 taacaacttc aaaacatgca tcatgatgat tttcagttta tatcaagttg aaaaagaaga
     6001 caaccaagcc taatattgga ctggttgcct aaaaataaat actctcagaa ttattattta
     6061 aaatagttta ttagtatcta aaaatcataa aattgaaaga gttactttaa gctgtttatt
     6121 tgataaaagt aattttaggt gttactccta aagataactt attcaacaca ttgaaaataa
     6181 tctttttatg gttgattata attatttcta taataatatt agtattgtcg gtattattta
     6241 aaattatcct ccttgaatct tcattaattt ctttacatat atatattgga aaaatatttt
     6301 tattaaaagt tatttttaaa ggttttgttg aaattttttc tggtcgccat actccttgga
     6361 gtatatgaag ccaatatttt tctgagaatt ccaaattatt atctttaata ttaattaatt
     6421 gatatttact cataagtttg cctttttata ttattaatac ccataaatag aactattcca
     6481 ttgataatga tctccattag atactggaat aatattactt tcagcatctt gagtcataaa
     6541 accacggtcc caagggttcc aaatcataat cacttcttgt ccaccttcta attctgcatt
     6601 accaactaca gccatagcat gtcctgcatg aataccgtct gttgattcta cacgacttcc
     6661 taaaatagca atgcctttat tattagtagt caatttatca acttcattat aagatggcat
     6721 tctattaaga tattgagtat ctctaccctg tgatttccca tacttcatca tttcttgagg
     6781 tgttaaacct gtaaattgga aatcatcacc ttgtaaattc ggatgtaaat atctcattac
     6841 tgcctcagca ttataacgat ctgtattata agttgcattc agtaatgctg acattgtata
     6901 tccagcacac caaccattat taccttgtgt ttctctgatt ttaaagtttt ttaattgatt
     6961 gacatattgt gctcggactc catatttggg attctcaaat tgtataatag gttttgtaac
     7021 tgaagctgtt tgtttaaagt tttttaaatc aatatttttg ggggattcca tcgtattttt
     7081 agaattcttt tcaccactat atggagtttt taatacatgt ttaattttat tatcttctgt
     7141 aactacaaaa taaccttttg tattggttaa aattgtgaat ttctgatttt catactgatt
     7201 taatattttt gaaagaaacg gagaaacatt aattgtataa tcactatttg aacttgtatt
     7261 tttatcgttt gcaattttag gagagattgt aacaacatat actactttac cttctttatt
     7321 taacacaggg aaatagtaat taccatcact cttctgattg aatttataaa ttttaaatgc
     7381 ttcacctaat gtgtaagatg aatttttttc tccggataat ttgtcaagtg ctgctacacg
     7441 tgaaagatat tgatcttcag ctagcttttt aactgccgat ggaatatctt ttttatcaat
     7501 attaactttt gtattttttt gatttggtag ttctttttgt gatgcttcct cagcattcac
     7561 attattaaaa aacagactaa ataccaaact aagtattaaa ccaattgcaa gaacaaagac
     7621 aatcgtacta atgttacata tttttttagc catagaaaac actccttttt atttttgtaa
     7681 ctctttcatt attaatataa cactctttct gcttttttat tatttttttc ctaaatgttt
     7741 atattaacga catatttgta taaaatatta attgataacg aaaatatttt tattaactta
     7801 atacctcaat aatcttattg aataaattta ttgaggtgta caatgacagt tggggctaag
     7861 tttaaacact ttaattaagt tagacattga ccctctgcat caatacacta tttataatag
     7921 ttttattatt tttttcttct aaatttgata taaaattagt attatattct taaaattacg
     7981 gataattttt ttgacgatat acttattatc tattgctttt aatatttcag atatatcacg
     8041 ataattcaat gcgtacctta agtattagcc tacgcctata gtgatgacat tcttatcgaa
     8101 ttatttatac ttcgaaagat taaataattt tttaagattt tagattatca aattaagctg
     8161 gatagtttat catcttcgat gaaactcata aatacttcca atggtgttct ataacctaaa
     8221 gattttctag gacgatgatt gattttttga gcaacactga tgatatgatt gtctgttact
     8281 aaattgaaat ctagttcttt atctaatcca ctgcgtctaa gtattccgtt agaatgttca
     8341 tttaagcctc tctgtgatgg cgtgcctgga tcagcaaaaa atatagatat atcatgacag
     8401 ttgcatattg ttttccagtt tgaaaactcc ttaccacaat caaaagtaat tgatttaaat
     8461 atatgagaag gtaaagctga aaacattgag tgcagagcat tttcggttct gttgcaaagt
     8521 taaatttata gtataatttt aactttgcaa cagaaccgga tttactaatt gaatggtgta
     8581 aatatcaaga tgaagatgtt tatgaacgct ataaaaatca tgaattacca gggcaaaaaa
     8641 taatatttgc aaaaaatata tattctagct gctacaaaat aacaaaaaag agtgcgttct
     8701 tattaaagaa tgcactcttt aaacttctct atattagaat taaagaactt aaaaataatg
     8761 atttgaaaac taattggtct atgataatga gataatttct tttgtaaaat caaatctgaa
     8821 catctaaaaa actaaaccac ttctattaat aattattttt ctctaaaaat tcttgtaaaa
     8881 ctttatctga tattgccttt atggacgtgt ctttgtctaa cgccatttga ctaagtcttc
     8941 tttttatcag agtatcaact ctcatagtcg aacttttagc cattggctta taattttctg
     9001 tatacttcac tgctgaagtg tctatgtcat ctaaaaatcc tcttttctgt tgtcctacga
     9061 ctttaatatt atctaaaaat cctgccattg caatcaccta tccttctatt aattctattc
     9121 tttcaatcaa ttctttatat atcgcttcta acatatgcaa aactctttta tcatgaacat
     9181 ctttatccct aataccttct gcaccgaatt tcttaattct ttctctttga aatatttgat
     9241 ttttaaacag agcatttgaa aaagtctttt tagatatttc caatatatat tcatcaatat
     9301 taccattttt cttgattaat acaggtatcg cacctattaa ttcaaacggt aaatttgatt
     9361 ctttttttct atctcttaaa aaattaacaa atgataaact gctttcatac gctgattgtt
     9421 gtgtctggaa taccatagca atgtagtcgc ttgcatatac agcattattt gtaaaatctg
     9481 aatttatcgt tggtggtaca tctataaaaa tgtagtcaaa attataattt tttttaattt
     9541 gatcaataac cgttttaagt atatatcgct tttttataat atctgttttt gcaataatat
     9601 ctgacaaatt agctagtgaa gaatctgcag gtaataaaga taatttcgtt gataaattta
     9661 taatactatc ttctaattcc cctgttttaa gagcatctat aaatgtttgt ttttcatcta
     9721 ttgcttctgg atatgttctt ttcataattt gggtagcgtt cccctgagga tcaaaatcaa
     9781 ctaatagaat tcttttatca tacctttcag agccaatata tgataataaa gttgatacag
     9841 tagtttttcc tacccctcct ttaaaattac caatagttat aactgacata tacaacactc
     9901 cttactgtta taatataata tattataaca gtaacttgtg acatgtcaca agttactgtt
     9961 atacaattcc aaaaaatcaa ctctaacaaa aacaaataag gaaagaggtt tttttattat
    10021 gtctcaatca ctacgtttta caaaactata caaattttta tttgaagatc ctacatttaa
    10081 aactttacca gcgaaagcca aattgctcta tgcattaatt tctgagcgtc aaagcttatc
    10141 gaaagctaat gctaagcaac atggcattca atcccaattt atcgataatg aggggcgttt
    10201 gttctccatt tatacgaatc aagaactgat gacgaaactt aatatgtcga aaccaacggt
    10261 aatcaaacta aaaaaacaat tgattgaatt tggtttatta gaagacgtgc gtctcggtaa
    10321 caatcaaccg aatcgtttat atcccaaaaa gccctatgat aactatttct atgcctatga
    10381 tgttgacgaa ttttatcgtc ttcctcatgc tttatttgaa aatcccaaat atcaatcttt
    10441 agcggctgaa tctatcattg cttatgcgat ttatctgagt cgttatgagt atagtatcta
    10501 taaaaatcat ttctcggatg aaaatggtgc agtctattgt tgtttctcta atgacaatat
    10561 ggcaaacatt ttagatgtga gtacacgaaa agtagaacgt atcaaaaaag aattgattgt
    10621 ttcgagtcta atgattaata agcgtgcatc ttttggtaaa tcgaatagat tatatatttc
    10681 actccctaaa gctagtgatg acaaggaagt taaaaaatgt cgcactagtt atacttattt
    10741 tagttatact tattctagtg atattgattc taatgatatg aatgatacgt atgataataa
    10801 tattgatgaa gtacatgaaa taaatgattc accacaaaca aatcattcaa gtcatccaaa
    10861 tcatcaacac aacacagagg atacgtttaa cgatcaacaa gtcgaacaag agatgttact
    10921 tcaacactta ccagactatg tacaattgaa cttaaaacat tttagtaata ctgaaattcg
    10981 ttgtattaaa tctgtactga ataaagcgaa agccagttat aatcaccacg cacctgtaga
    11041 tgaacgtgtt acgtatgaag cctgtaccta tgctattggg gaagctttac gacgtatcaa
    11101 actattaagc cgacaaaaaa atgaaaatat ctgcgatcta gaagcctaca tgatgcaaac
    11161 atttaagcgt gtctttgttg aacatgtgct gaacgaccaa cagaaacttg acgatactaa
    11221 aacaaaaacg catgatattt cacaatttga accgaaaaat gcgttccaat cgatggcaaa
    11281 acgtatgttt cttgatgttt gataacttta atatttagga aggagagata gttgtgaatg
    11341 aaaaagagat agggattgcg tttttgaacc actttacgca agtggaggct tatttagagg
    11401 ctttaggtgt gcccgaaaac catatcgcag atattaagcc gatagtcatt cagaactatc
    11461 cctatgaacg ctttttgttt gatgatttag gcgatgtaac gaatgtgatc attccctttt
    11521 ctaaagtcat tgggagtaac ttatttggga atattggcta caagtagttt gacttagtga
    11581 aatggtcgct agaacagaac tttcatggta acgcgcctaa ccttaaaccc caaaaaatac
    11641 aaggctgttt aggttttcta aaatcgttag gttgggaaaa ttggaatcaa agttatcaaa
    11701 cattggatat tggagaactc tattttagtt tgctacttga tgacaaaggg catgtgataa
    11761 cctatatgca tgaaggtggc aatggcggcg gtagacatcg aatatttact ggtaaagtct
    11821 gtggtgcaga atatgtcaga gctgcgagat tgacacaatt tagattaaat aaacaaaaat
    11881 tggcatatta taaaaataat tggtacttga gcaacaaatt aaagatatta tttaaaaagg
    11941 tgaattgttt caaattgttt gtttcgtata ttttatttat gttttgaaag gagtatcttt
    12001 tcatgaaaaa aatattatta ttagtgagca catgtttatt atatttagat tgtcaaatta
    12061 agctggacag tttatcatcg gttctgttgc aaagttagaa aaacatctaa tttccttttt
    12121 tatcatttca gtgttagttt aactagctaa catatgactg atttcgtagc atggcgaaaa
    12181 tccatagatc tgaagagacc tacggttctt tttatataat ccgtaaatac attcaatgcc
    12241 tttgagtgta ttttttgccg tattgagact ttgatacctt gtctttcgta ccttaatatg
    12301 acgatgatct tgttcaatga ggttattgag atatttagat gtgcaatgac agttagggtt
    12361 cagcttaaac actttcacta ttttagtcat tgcaaccttc gttgaaggtg cttgatctgt
    12421 aattatcatt tgaggtttac cgaattgttt aataagacgc ttaataaacg catatgctga
    12481 ttgatgatct cgttttttac gcaaccaaat gtctaatgta tgtccttctg catcaatggc
    12541 acgatataaa tagttccatt ttccttttat tttgatatac gtctcatcaa tacgccattt
    12601 gtaataagct tttttatgct ttttcttcca aatctgatac acaatcggtg catattcttg
    12661 aacccaacga tagactgttg aatgatgaac attgacacca cgttccctta atatttcaga
    12721 tatgtcacga taactcaatg catatcttag atagtagcca acggctacag tgataacacc
    12781 cttgttaaat tgtttatatc tgaaatagtt catacagaag actccttttt gttaaaatta
    12841 tactatcaat tcaactttgc aacagaaccc tagcaagtta atacgaagta ttattttaaa
    12901 catgagtcta gaggtttatt ttttaacttt gcaacataac tgttttagat atatgtgtag
    12961 gagtaaaact tttttgcgaa gaataagtat ataaataaat tggagataag tataattaca
    13021 ttgacgttta taggaaatgt agttattttg gttccatttg tacttgtagc gataagtgag
    13081 aatggtaata gtagtggaga agataatgat tttaataggt atggttgtat gattttaaaa
    13141 tattagctat caaaaaatat ttttatagag aaaataataa aaaacatcta gatcagtttg
    13201 taccttgaaa tttgaaatca ataaaaaaac gaccactaac acctcatagc tattatacta
    13261 caaatattgt ggtcgttctg aagacttcat tcatttggag gtgaggcata agtactcgtg
    13321 ggggatatcc taacctctct tttttgaatt gtgtattttg atgttgataa taaactaaaa
    13381 tactgctgtt tttattgtaa aaaccaaata gcaatttgag ctactaaatt atttagtaca
    13441 tggatagaga gtatataata aaagttgtgt ttttttaaat aaataaaaac tgttactatg
    13501 cctattgaaa aataggggat taatgtcttc caatcttctg ttaaactatg catatgtatt
    13561 accgtaaaag acgatataga aattaatatt gcagggagta atttaatttt gtttttaaga
    13621 acttctaaaa tatatactct gaaaagtaat tcttcaagta taggtccaat gataacaatt
    13681 aataatggtg caaaaaattg agataaaaat gaaatatttt caatggcatt ttggttaaca
    13741 ctctttactg gtctgccttg attaataatt aatataagta ttacatttaa aagaagaatt
    13801 agaaaaaagc ctactattcc tgtaagaaag acaccaattt ttttgttttt aatatttaac
    13861 caatctttct gtagttttac tttaaatatt ttaatggcat atatcatcaa aatagttgta
    13921 ataacaaaaa aataccattc attaattata tcgtaattta tatttagttt gtttgaaaac
    13981 ggtaatattg cgtatctggg gataatgatg agtagtatta tataaattaa agctaaatag
    14041 tgactttggt gaatgttatt taaatttttg tacatggaaa tctcctgaat tttttataat
    14101 tactaagtat ttgtttaaaa gttatttgga tttgctttgt attcccattt taagaagcaa
    14161 agaagtttat aaaggtataa taaatactat attttgccct gttacgaaat taaatctata
    14221 gtatactttt agctttgcaa caaaatcctt tataacgttg gcttaagata agtttttatc
    14281 gcttttaata tatcattttt taaattgtcc tgtagttcgt ctttatagtt gtattgacgt
    14341 gcttttaggt ctaaagcgcg tatttgaaca gtgtctatca caccagatac taatcctttt
    14401 tttgttttaa gttggatatc tgttggataa cgtaaacccc gagttgttat gggtaaaacc
    14461 caaacaaaat tagtgccatc aatactcatc tgattattta tcactaagca gggccttacg
    14521 ttatgctttt cacgtccacg agttggattt aaatcaatgt agagtatgtc aaattgttta
    14581 atgttcatat ttctcggcca actctttctt cccaatctac ttctaattct gtatactttc
    14641 caccactttg aaagaaattt ttaattctat cttcaataga ctcctttttt ttagtaatga
    14701 acaaaccacc attcattttt tgaacttcaa ctgtatctcc tatatcaaaa ttagctaacc
    14761 tgatagtttt tttacttaaa ctgattgctt tactgtttcc atttttaaaa actcgttccg
    14821 aagtcttgtt taagtctttt aatgatttag ccattattat cagccccctt ttgttcatca
    14881 taacaaatgt agttaccaaa gtaaatacat atgaagttga ataatttata aaaatcaaaa
    14941 acatcgcttt tactatcctc gactgcattt tttacaaagg tgaaaagtaa atatttaatt
    15001 tttcgtttaa ggtaatcgtt ttcttaactt tctagtatga cgataatttt gctcaatgag
    15061 ttcgttaagg tatttatatt tataatgaca gttaatatta aggttaatat cttgaattaa
    15121 ttcggacatt gcccttctta tttaattttg atatatatct tatcaacata cagtttaaag
    15181 ttaaccctaa gttctctttc catatatcac aataactcaa cgtctatctt aatcaacaat
    15241 catcaactat atcgttgcta cctttatcaa attgtttata gctgcagtag ttcatgtaga
    15301 atatttcttt gtgttaatac cataccataa aattaacttt gcaatagaat ctatatttat
    15361 aattatttta cccatttatg ttaattaatg gtaaaataat tataaatata gagaggttaa
    15421 aagaatgaac tatataaaat atatacatag tgtagatgga acaactttat atgttaaagt
    15481 gaatgaaaat gtaaatagta gcgctaatat cattatatgt catggattag cagagcattt
    15541 agatcgctat gacgaaattt caaactattt gcaggagaaa aattttaata ttataagatt
    15601 tgatcaacga ggacatggaa ggtctggagg aaaacgaact ttttatagca atgtaaatga
    15661 gatagttgag gacttagatg ctgttattaa tttcaccaaa gaacattata aaggtaatat
    15721 ctatctgatt gggcatagta tgggaggata tgggtctgta ctttattcta ctaaaaaccc
    15781 tggaaagatt aatggtttaa ttatatctgg agcagtaaca aggtataatc agaaaacttt
    15841 tggagacatt gatgatacaa ttgatagaaa taagtatatt aattatgaaa ttggagaggg
    15901 agtgtgtagt gatacttttg agttagaaaa atatagatta gatgcattaa ctgaaaaaaa
    15961 ggtatcttac ggcttgatat acactgtttt ggaaggtgta aaaggcttag tggaaaatgc
    16021 tcaatatttt gatgataata ttttaatttt acatggcaaa gatgatgggt tggttcatta
    16081 cagtgactct ttagattttt ataaaaacat ttcttcttca aaaaaagaat tacatattta
    16141 tgatggttta caacacgaaa tttttaacga gagaaaaaag aataaagaaa ttttttcgga
    16201 gattgcaaac tggataaata atgatttaac ttgagaatcc gattgataaa tttgaataag
    16261 tcggttctgt tgcaaagttt aaaaataagt gtccagcttt atctttaaaa gttttacttc
    16321 agaagaaatt agaaaggatt attttgatga aaaaaacaac aatatatttt gttctatatt
    16381 ttattataag cgctcttggt tttggtatgt tgaaaaaatt agggatagaa tataatagtt
    16441 tggaaattgc agtatatgcc cttcctatga tgataatttt gtcaatattt gtttactcaa
    16501 tagctttgaa tccctatcaa aaaagaaaaa gttctcctat aatacatgta aaatcattgg
    16561 aatatgtggt tccattggtt atattatgtg atatattaat aattttagaa ttattatata
    16621 ctggtaattt tagacccata ttagtggcac agttattttt aacctttctt attggttttt
    16681 cagaagaatt cttctttaga aaatatatta ttgaacatat attgactaaa tacaaatcaa
    16741 aactgttagc ccttattact tcttctatac tttttggttt actacatatg gcaaatacct
    16801 ttggtggctt aactattgaa aatgctgctt ctcaatctat gtcagctaca ggagtaggat
    16861 tattatatgg tttaatatat atattcacaa aaaaaatatg gatgttggta ttattgcaca
    16921 tgaacgttga tttcgcttta ttttcgtctg taataaatca atcatattta caagcagtac
    16981 cagcctttat tgtggatatt attttaattt ttactgtttt aaagataatt atgtatatac
    17041 tcaagtcaat taaatctaaa aataataagt ttttatagag gatacataga aatattacgg
    17101 ttctgttgca aagttaaaaa tcatataata taaatacaga gaaatgagaa aataaccaaa
    17161 tctcccgaaa taatctattg ttattgcagc attttgttta ttgattttgt atagatttgt
    17221 atactaattt aactttgcaa cagaaccctt attgttg
//
