LOCUS       NZ_MF449287            33303 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Escherichia coli strain T71115 plasmid pIBMC_mcr1, complete
            sequence.
ACCESSION   NZ_MF449287
VERSION     NZ_MF449287.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14227648
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33303)
  AUTHORS   Caltagirone,M., Nucleo,E., Spalla,M., Zara,F., Novazzi,F.,
            Marchetti,V.M., Piazza,A., Bitar,I., De Cicco,M., Paolucci,S.,
            Pilla,G., Migliavacca,R. and Pagani,L.
  TITLE     Occurrence of Extended Spectrum beta-Lactamases, KPC-Type, and
            MCR-1.2-Producing Enterobacteriaceae from Wells, River Water, and
            Wastewater Treatment Plants in Oltrepo Pavese Area, Northern Italy
  JOURNAL   Front Microbiol 8, 2232 (2017)
   PUBMED   29176971
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33303)
  AUTHORS   Bitar,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUL-2017) Microbiology, University of Pavia, via
            brambilla 74, Pavia, Pv 27100, Italy
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: Spades v. 3.10
            Sequencing Technology             :: Illumina
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009977455.1-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 01:58:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 40
            CDSs (total)                      :: 40
            Genes (coding)                    :: 38
            CDSs (with protein)               :: 38
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 2
            CDSs (without protein)            :: 2
            Pseudo Genes (ambiguous residues) :: 0 of 2
            Pseudo Genes (frameshifted)       :: 1 of 2
            Pseudo Genes (incomplete)         :: 1 of 2
            Pseudo Genes (internal stop)      :: 1 of 2
            Pseudo Genes (multiple problems)  :: 1 of 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MF449287.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33303
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="T71115"
                     /db_xref="taxon:562"
                     /plasmid="pIBMC_mcr1"
     gene            join(32939..33303,1..340)
                     /locus_tag="HTO21_RS00005"
     CDS             join(32939..33303,1..340)
                     /locus_tag="HTO21_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067834.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YISSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            1123..1218
                     /gene="dqlB"
                     /locus_tag="HTO21_RS00200"
     CDS             1123..1218
                     /gene="dqlB"
                     /locus_tag="HTO21_RS00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            1881..2528
                     /locus_tag="HTO21_RS00010"
     CDS             1881..2528
                     /locus_tag="HTO21_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            2603..2872
                     /locus_tag="HTO21_RS00015"
     CDS             2603..2872
                     /locus_tag="HTO21_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            3033..3737
                     /locus_tag="HTO21_RS00020"
     CDS             3033..3737
                     /locus_tag="HTO21_RS00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_225236207.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLQIINTLKCIFSMGLRND
                     CLIKFLKYFCIA"
                     /name="DUF2806 domain-containing protein"
     gene            3831..5456
                     /locus_tag="HTO21_RS00025"
     CDS             3831..5456
                     /locus_tag="HTO21_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.2"
                     /protein_id="WP_065274078.1"
                     /translation="MMLHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.2"
     gene            5504..6250
                     /locus_tag="HTO21_RS00030"
     CDS             5504..6250
                     /locus_tag="HTO21_RS00030"
                     /inference="COORDINATES: protein motif:HMM:NF028536.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_077248209.1"
                     /translation="MGGGVGFVMPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVA
                     DWFYLGMGHWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKW
                     LVPVTKFRVRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRN
                     TIPDKCFPAAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSH
                     TVVSMMLAWAMSAGLAWVFFKKGEQV"
                     /name="PAP2 family protein"
     gene            complement(6641..7168)
                     /locus_tag="HTO21_RS00035"
     CDS             complement(6641..7168)
                     /locus_tag="HTO21_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(7303..7707)
                     /locus_tag="HTO21_RS00040"
     CDS             complement(7303..7707)
                     /locus_tag="HTO21_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(7720..8586)
                     /locus_tag="HTO21_RS00045"
     CDS             complement(7720..8586)
                     /locus_tag="HTO21_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473366.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001353743.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGVKDYKYPDYPAF
                     KRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFD
                     KMYPPEN"
                     /name="replication initiation protein"
     gene            10001..10516
                     /locus_tag="HTO21_RS00050"
     CDS             10001..10516
                     /locus_tag="HTO21_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            10621..11163
                     /locus_tag="HTO21_RS00055"
     CDS             10621..11163
                     /locus_tag="HTO21_RS00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            11160..11411
                     /locus_tag="HTO21_RS00060"
     CDS             11160..11411
                     /locus_tag="HTO21_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            11398..11625
                     /locus_tag="HTO21_RS00065"
     CDS             11398..11625
                     /locus_tag="HTO21_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            12160..12378
                     /locus_tag="HTO21_RS00070"
     CDS             12160..12378
                     /locus_tag="HTO21_RS00070"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005058042.1"
                     /translation="MHKDTGQQYVVIFTDNNKIRDYKAGIVPQFGELKQSDVDLVLFYR
                     DEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            12469..12819
                     /locus_tag="HTO21_RS00075"
     CDS             12469..12819
                     /locus_tag="HTO21_RS00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            13124..13372
                     /locus_tag="HTO21_RS00080"
     CDS             13124..13372
                     /locus_tag="HTO21_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            13369..13716
                     /locus_tag="HTO21_RS00085"
     CDS             13369..13716
                     /locus_tag="HTO21_RS00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            14077..14580
                     /gene="taxA"
                     /locus_tag="HTO21_RS00090"
     CDS             14077..14580
                     /gene="taxA"
                     /locus_tag="HTO21_RS00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            14584..15813
                     /gene="taxC"
                     /locus_tag="HTO21_RS00095"
     CDS             14584..15813
                     /gene="taxC"
                     /locus_tag="HTO21_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            15890..16183
                     /locus_tag="HTO21_RS00100"
     CDS             15890..16183
                     /locus_tag="HTO21_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_060598542.1"
                     /translation="MTEHDAICISGLHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            16180..16395
                     /locus_tag="HTO21_RS00105"
     CDS             16180..16395
                     /locus_tag="HTO21_RS00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            16751..17370
                     /locus_tag="HTO21_RS00110"
                     /pseudo=""
     CDS             16751..17370
                     /locus_tag="HTO21_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /name="lytic transglycosylase domain-containing protein"
     gene            17384..17710
                     /locus_tag="HTO21_RS00115"
     CDS             17384..17710
                     /locus_tag="HTO21_RS00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            17729..20476
                     /locus_tag="HTO21_RS00120"
     CDS             17729..20476
                     /locus_tag="HTO21_RS00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            20488..21204
                     /locus_tag="HTO21_RS00125"
     CDS             20488..21204
                     /locus_tag="HTO21_RS00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            21216..22310
                     /locus_tag="HTO21_RS00130"
     CDS             21216..22310
                     /locus_tag="HTO21_RS00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_172692400.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRAGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            22337..22486
                     /locus_tag="HTO21_RS00135"
     CDS             22337..22486
                     /locus_tag="HTO21_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227648764.1"
                     /translation="MSLNWILVFVDKHITSGWSRKRKLITQLVILITGITLFKVLGGIS
                     QSWL"
                     /name="hypothetical protein"
     gene            22825..23511
                     /locus_tag="HTO21_RS00140"
     CDS             22825..23511
                     /locus_tag="HTO21_RS00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            23508..24416
                     /gene="virB9"
                     /locus_tag="HTO21_RS00145"
     CDS             23508..24416
                     /gene="virB9"
                     /locus_tag="HTO21_RS00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            24409..25527
                     /gene="virB10"
                     /locus_tag="HTO21_RS00150"
     CDS             24409..25527
                     /gene="virB10"
                     /locus_tag="HTO21_RS00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            25529..26557
                     /gene="virB11"
                     /locus_tag="HTO21_RS00155"
     CDS             25529..26557
                     /gene="virB11"
                     /locus_tag="HTO21_RS00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017226.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            26544..28406
                     /gene="taxB"
                     /locus_tag="HTO21_RS00160"
     CDS             26544..28406
                     /gene="taxB"
                     /locus_tag="HTO21_RS00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            28415..28837
                     /locus_tag="HTO21_RS00165"
     CDS             28415..28837
                     /locus_tag="HTO21_RS00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            28821..29126
                     /locus_tag="HTO21_RS00170"
     CDS             28821..29126
                     /locus_tag="HTO21_RS00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_001350475.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            <29239..29433
                     /locus_tag="HTO21_RS00175"
                     /pseudo=""
     CDS             <29239..29433
                     /locus_tag="HTO21_RS00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            29437..30009
                     /locus_tag="HTO21_RS00180"
     CDS             29437..30009
                     /locus_tag="HTO21_RS00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001198960.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            30014..32167
                     /locus_tag="HTO21_RS00185"
     CDS             30014..32167
                     /locus_tag="HTO21_RS00185"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            32164..32370
                     /gene="hha"
                     /locus_tag="HTO21_RS00190"
     CDS             32164..32370
                     /gene="hha"
                     /locus_tag="HTO21_RS00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            32388..32852
                     /locus_tag="HTO21_RS00195"
     CDS             32388..32852
                     /locus_tag="HTO21_RS00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     ARG             3832..5453
                     /name="mcr-1.2"
                     /gene="mcr-1.2"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.2"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(7721..8592)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          14585..15810
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          21217..22283
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.438"
                     /coverage="99.0"
                     /evalue="1.5699999999999998e-172"
     Typing          22826..23508
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          23509..24413
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          26545..28403
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cctcaacaac gtgaagaagt ggcagatccc gcgattcatc aacacggata aagcgcccgc
       61 ctatggtcgc gcgcttgctc tgctcaaacg cgaaggccgg tgcccgtctg acgttgaaca
      121 ccgacagatt aagtaccgga acaacgtgat tgaatgcgat catggcaaac tgaaacggat
      181 aatcggcgcc acgctgggat ttaaatccat gaagacggct tacgccacca tcaaaggtat
      241 tgaggtgatg cgtgcactac gcaaaggcca ggcctcagca ttttattatg gtgatcccct
      301 gggcgaaatg cgcctggtaa gcagagtttt tgaaatgtaa ggcctttgaa taagacaaaa
      361 ggctgcctca tcgctaactt tgcaacagtg cctcacacag acatacacat aggtatgtct
      421 gtgtgacata cctatgtaca gtgccagatg gcgttgctac gtgaaaaata acctacccta
      481 cccctgcttt tttcgcagat tttacgtagc acaccgttgc tatagcattc atctaaaaag
      541 ctgaatgtcc ttttctgtcg ctgttgcatt ttaattcact gaaaaatatt gagtaatgaa
      601 aatgccggta acgcgtcaag ctgttggcca acgcgacagg cagtattgga agcaacaaaa
      661 aaaatgaaag aaaaatccct caaatgaagg agaaaaaacg gaactacagc cgaacgacag
      721 gcacaaaaaa acccgactgg taatcgggct tttttgcgtt ttccagtctt gagttggtgg
      781 ctctgaccgg agaaggttac tctacaccta acgtttacat tttattcact atggtgctgt
      841 aaagcaacta aatgtggtta aggaaccaca tttagtggtg taacgggtgt tttgtgtagc
      901 gtataatcag tcagttagtc atgtagttgg cttgcaatcc tgctgttccc gtatctgcgg
      961 gtatgaacga ttttaaagtc ctggctggat aaacaggtgg tgctgtattc ggtgctctgg
     1021 caggaggagg tcactctaca cctaacaatg cgagagagcc gttgtgacag gcagtgtatg
     1081 agcaagcaac ggtgatttcc tccagtttta ctggagaaac ggatgattaa tatgttaatc
     1141 atcgttctca gagctgtggt cgccgttgca aacgcgctga ttgcagttct ggaactgatc
     1201 cgccaattca tcgattgatg acaacggaaa cgtaactaag ggcaggaagt gaaccgcttc
     1261 ctgcccttta acaaaaaagg aggatttatg gattttatga gcattttggg gcgctgttta
     1321 cttcttcctt tccctgttgc gatgtttgtc ggttgcctgt ttcctggcat cgatgatcgc
     1381 ttatccggaa tgcttatgag tgttgctgtg ggatgtttat cgtggtatgt caccagaccg
     1441 aagaaccgac agacaaaggc cgcgtaagtg gcctttaatt gggataccct ttagttacaa
     1501 cattctaata gctcattcca tcctccgctc atccagcaaa cataacctcc ctgcccctcc
     1561 ccactacaga aagtggcgcg ccccgcccgt acgggcggaa tctaatcgct taattttgaa
     1621 tgttgtaact aaacatactc attgctgtat tgccacaagg tttcgcagca agggaggata
     1681 ccgaaagtaa cgctgtcact tttgctttca agtgaccaac caacgggtac atcacactga
     1741 catacaataa tgtatttctt catgatgtac atcattgtaa ttcattgtga catacactat
     1801 agtatgtcca tgtgacatac gcatgcgtac atcacataga aatacacatg agtaaatcac
     1861 tgtgacatac aaggggtact atgattatcg taatcggtgg tgataaaggc ggtacaggta
     1921 aatcacatct ggcaaccaac ttaactgttt gcctctcaca acagggaaag agaacggggc
     1981 ttgttgaaac agacctgaat ggctcgacca aaaaatggaa taaacgcaga gaacaggccg
     2041 gattaccgcc cgtcgcatta aatgaagcct atggcgacat cagtgccaaa ataacaaaaa
     2101 tggcagatgt agcagaaatc ctcattatag atactgccgg atatgacagc acggagttca
     2161 gaactgcact aaaagttgca gacattgtga ttgtcccgat cgacccgctt gcccaggtgg
     2221 aagcagacag tcttcagact gtgacaaaaa ttgtcaggga tgcgcaaaaa ataaatccca
     2281 ggctggctgc acatgtgctc ctgtataaat gccagccaaa tacgttcagt gaacaacaag
     2341 aattaagaga ctctctcaac agccatgatt actggcttaa accaatgaaa agcacggttt
     2401 cttttctccg ggcctttgta agagcaatga atcagggaat gggggttcac gagttaaaaa
     2461 gtaatgttag cggtgccagc caggcaaaag cacaaatcga actcttgctg aaagaactgg
     2521 aactgtaaat catagtgaca tacactaatg tacatcatca tgatatacat tagtgtgaaa
     2581 caatcagatt agaaggtaca tcatggcaaa gctggaacta ccagaactag aacaaaacca
     2641 ggaagtgaac gccacaaaat ttgttcagga cgcaggaaaa cgccccacag agaacaaaac
     2701 aaaactggct tcattccgca taccgaatga attgcttgaa ttcattgata acgaatcaaa
     2761 aagactgcat cgtcccaaga caaaaataat caaagcagca ttactggctt atcaggatct
     2821 ggacgaaaac gaactcatta atttgtggtt cagagctgac agaaatgatt aatcatagca
     2881 agtggcccaa taaactcttt atcattttct tttagatact tatctgaatg tactaacttc
     2941 atcactttta aatgtagttg tgattcattt ttagttactc ttgcaataaa atacccttgt
     3001 acagttgttg cacgggtatt taggagcact agatgagcct tatcgattta agtttatcag
     3061 gattatcaga accaggaaca aaacttattg aaaaaataag tgatgctatt ggtgtgcttt
     3121 atgaacctac aagaatcagg aaaaaagcga aggctgaagc tgaagctaaa cgcacagagc
     3181 taatttctag gttagagctt gagggaatag aaaaacgggc agttgagcgt tttctcaaac
     3241 gtgaaacgaa acgacaggaa aacattgaaa atataacaat gcaagcagca caaagtctat
     3301 ctgagagtga taatgtttct gatattgacg aagattggat agaggctttc ttcagggagt
     3361 gtgaggatat tagtgacgaa caaatgcaaa tgctttgggg aagaatttta tccgaagaag
     3421 caaagtcaaa aggttcgttt agtcgtagaa ccttaaaact attatccact ataagcaaag
     3481 aagaagcgaa ccttattact tattttggaa agtttgtttg gcaggcaaac aaactcactc
     3541 caattttatt taccgatgag aatggagata ctgaaggtat aactttcgat aaactttcgg
     3601 ttttagactc cttaggcgtt attcaacaag gcattggtta tagtttacaa attataaata
     3661 ctctcaagtg tatattcagt atgggattgc gcaatgattg cctaataaaa tttctgaaat
     3721 atttctgtat cgcataattt tttatatcag ataaattgta ctggatttct taaaaaattg
     3781 cagtataatt gccgcaatta tcccaccgtt tattttttga gtagtttctc atgatgctgc
     3841 atacttctgt gtggtaccga cgctcggtca gtccgtttgt tcttgtggcg agtgttgccg
     3901 ttttcttgac cgcgaccgcc aatcttacct tttttgataa aatcagccaa acctatccca
     3961 tcgcggacaa tctcggcttt gtgctgacga tcgctgtcgt gctctttggc gcgatgctac
     4021 tgatcaccac gctgttatca tcgtatcgct atgtgctaaa gcctgtgttg attttgctat
     4081 taatcatggg cgcggtgacc agttatttta ctgacactta tggcacggtc tatgatacga
     4141 ccatgctcca aaatgcccta cagaccgacc aagccgagac caaggatcta ttaaacgcag
     4201 cgtttatcat gcgtatcatt ggtttgggtg tgctaccaag tttgcttgtg gcttttgtta
     4261 aggtggatta tccgacttgg ggcaagggtt tgatgcgccg attgggcttg atcgtggcaa
     4321 gtcttgcgct gattttactg cctgtggtgg cgttcagcag tcattatgcc agtttctttc
     4381 gcgtgcataa gccgctgcgt agctatgtca atccgatcat gccaatctac tcggtgggta
     4441 agcttgccag tattgagtat aaaaaagcca gtgcgccaaa agataccatt tatcacgcca
     4501 aagacgcggt acaagcaacc aagcctgata tgcgtaagcc acgcctagtg gtgttcgtcg
     4561 tcggtgagac ggcacgcgcc gatcatgtca gcttcaatgg ctatgagcgc gatactttcc
     4621 cacagcttgc caagatcgat ggcgtgacca attttagcaa tgtcacatcg tgcggcacat
     4681 cgacggcgta ttctgtgccg tgtatgttca gctatctggg cgcggatgag tatgatgtcg
     4741 ataccgccaa ataccaagaa aatgtgctgg atacgctgga tcgcttgggc gtaagtatct
     4801 tgtggcgtga taataattcg gactcaaaag gcgtgatgga taagctgcca aaagcgcaat
     4861 ttgccgatta taaatccgcg accaacaacg ccatctgcaa caccaatcct tataacgaat
     4921 gccgcgatgt cggtatgctc gttggcttag atgactttgt cgctgccaat aacggcaaag
     4981 atatgctgat catgctgcac caaatgggca atcacgggcc tgcgtatttt aagcgatatg
     5041 atgaaaagtt tgccaaattc acgccagtgt gtgaaggtaa tgagcttgcc aagtgcgaac
     5101 atcagtcctt gatcaatgct tatgacaatg ccttgcttgc caccgatgat ttcatcgctc
     5161 aaagtatcca gtggctgcag acgcacagca atgcctatga tgtctcaatg ctgtatgtca
     5221 gcgatcatgg cgaaagtctg ggtgagaacg gtgtctatct acatggtatg ccaaatgcct
     5281 ttgcaccaaa agaacagcgc agtgtgcctg catttttctg gacggataag caaactggca
     5341 tcacgccaat ggcaaccgat accgtcctga cccatgacgc gatcacgccg acattattaa
     5401 agctgtttga tgtcaccgcg gacaaagtca aagaccgcac cgcattcatc cgctgatttc
     5461 tccctgtatt ttttccaaac ccaccgcaca ctccattcgt attatgggcg gtggggtggg
     5521 gtttgttatg ccgtatttat caaataaacg cctacttgct gagatgagta tcgctcttgt
     5581 catggcgatc gttgccacgc tgacccttga gcacagtcag attgatctga tggtcgctga
     5641 ttggttttat ctgggtatgg ggcattggat ggttgccaag caagcttttt tgccagattt
     5701 gctactgtat tctggactaa aaaagctgct gatggcgatg ctgatctact tgctggttgc
     5761 gaccatttgc cgtgcttatc atgagaaaaa gggcaatgct atcactgcca agtggcttgt
     5821 cccagtgaca aaatttcgcg tgcgtgagct tgcgtatctg gtgctgactt tgatcctagt
     5881 gccgacagtt gtcgcgtcat tgaaggcata tactcatgtg gtctgccctg tgcatttgac
     5941 gatttttgat ggtacgctgc cgtatttgcc gatgcttgat agtatgcgta acaccattcc
     6001 tgataagtgc tttcctgcgg cgcatgccag tagcggattt gcgctgtttg cctttgcgtt
     6061 tgcgccaagt ttgcgccgcc gtcgtggtgc gatcatcatc gtggtgatgg cattgggctg
     6121 ggcgatgggc tgctataaga tgattattgg cgatcatttt ttgagccata cggtggtgtc
     6181 gatgatgctt gcgtgggcga tgtcggcagg gcttgcgtgg gtgtttttta agaagggtga
     6241 acaagtttaa tcgcctttaa aagtaaaaac ggtcgtatcg gttattacgg aacggttttt
     6301 tcagttgagt ttcaaagcga tgattcatca acctggaaac taccaatagg aacggcttta
     6361 cttacgccta tcggtcaaga attgatgaaa atatgcggtt ccactccaga tattgcgtat
     6421 ttaaataaat tcctcaacaa aataaatgtt gaaggaagcc aggtaaaact atcaattatt
     6481 aatatgtaaa gaggtcgagt tacctgtctg agttccacta accataatta aaagcgaccg
     6541 caaaaactgc ccagtgaaaa ctgtgttgcc agtaatcaca aatgcagcaa gtactaataa
     6601 agagcctgtt aagcccgcaa atatgtgggc ttatttttaa ttactcttca tcatcccgca
     6661 ggaactgaca aaaatcttcg ctccccatca tatcgacagt gtttttaaat tcgaaaaaag
     6721 aaattcctgt catagcacac acgcgctgga taatcagttt tttcttttgc tgtctgacgg
     6781 ttgcggtttc accaaactgg ataacagcca ggactgtttc atcatatgat ttcaggacaa
     6841 aatcacaggt tatattctgc acttcacgga ttaaatcttt tacagcttcc tcgctaccat
     6901 gaggacgaac aaattcaatg agccgtattt tgggaaaaac ggaataatca ggtataatat
     6961 tacgtgaaag aatgcctaaa aactctgatt cattatttga gagtaagggt actttagtaa
     7021 aacaatcaac ctccccaatg gctgtaaaag cattggttgt caaagctgga ttgttcttaa
     7081 taaaatcaga gaatacattt tcagctgatg gcaaaacaac agcagaatta tgttgttcat
     7141 ctcgtttttt attacggtta aatatcattt catattcctt ttaaaagagc ctgcggcagg
     7201 cacaggcaaa aacatcgttt ttggacaatc tgattcaaat gttaacattt gacatcggat
     7261 tgtctatcct gcattgttct ttactgtctg taagatcggc gctcattctt ccggcgttct
     7321 cccgatacca aaaagacgga acgcaaaacg gctttcgatc caccattcaa aaatctgctc
     7381 tgcgcaacca caaacagtta aggcgatcca tgcagcaaga acaacgtaac tactgacatc
     7441 tgcacccatg taccaggcga tagttaaacc catcactgcg ataccgccta aaaactgcaa
     7501 caagaaacga aatcccgcaa gaatccccaa tggaataaca acaaccagat aaagggaagc
     7561 agccagaagg tatctgacag gtgtcagcag ataaaagaac ctggatattt tctttttgtc
     7621 agaataaacg gcatcatttg caacatcggt tgaatgatca ttcatgctgt ccctgattct
     7681 ttgaaaatct acgatattat ccttcatatt gttatgacct caattttcag gtgggtacat
     7741 tttatcaaac atattagtaa actctgagtc ttccctggta tcgccctcat aaccaattgt
     7801 ataagagaac tttaatttat aaacttttct cccaattttt tctgaaacta cgaaacttaa
     7861 gttctttact tccgtatgtt tcatgatttc ttttactgat ttattaagaa catctctttt
     7921 aaaagcagga taatctggat acttataatc cttcaccccc cccgccccta ttgtataaag
     7981 attcaattca tctttaagtt catctattgt catttcaaaa ctattcgcgc gagaattatt
     8041 actatatatt ttacgaatga gttgatatag tgatgcagca ttaacacttg tcagtcgaac
     8101 aacagataat aaaacttgcg ttgtataacg tttttcttca ccaataagtt tacataaaaa
     8161 tcttttcgct tctttcgtaa acttgatccc cactctacct tcattcctgt aataagtaga
     8221 aaaaacagtc agactcaaat tcattgaatc aggtacatta cttttagtga acttaaatcc
     8281 caaatcacta ctcagttcta atatttcatc atgtttcagc ttaagaagcg tcgtatctaa
     8341 tatattagag ccatccctca aagcaagata agccgcatca ggcttaacct gaacccattt
     8401 aatgtaatcg gcaactgtca cataaaatat gtgatcatca tcgaattcat ttttagagtt
     8461 tatctggcac atggctaaaa ataagacttt tttagcagcc ataggcaatg ttgacagcgt
     8521 tgaattcaat tcatttcgat gtctcacttt tgttaagcga gaaagggaag tcttatttgt
     8581 cgtcattctc attgttccaa cactcttgat aatcagactt taacaccaga aacatgatat
     8641 tacaacacaa tcaatatcat gtttaaccga gtatcttctc atgtttcata tctgtgattt
     8701 atctcacaaa ggtaatccat gctcaaaatc cacactggat tcaaggcaga ttaacaacag
     8761 attcaaaata gattcaccag aaagaacaac gaattagtat tcttatgaca cattttgtgg
     8821 atatcaccga ggaagctctc atgtttaacc gaggaagctc tcatgtttaa ccgaggaagc
     8881 tctcatgttt aaccgaggaa gctctcatgt ttaaccgagg aagttatcat gtttaaccga
     8941 ggaagctctc atgtttagac aaaaaacacg cttaaaatca ataaattaga gctactctaa
     9001 gtttttaagt ttttaagaaa aacaagaaaa gataaggctt ttaatgcgtg cgaatattca
     9061 ggaactgtgg ataactcaac aaaaccagca acgatgatgg ttccttacca taaatctgtc
     9121 ccccgatgat tattacccgc aagctaaaac aaacatcatc aatcattaaa actcataact
     9181 ttcaataaca taaaatcatc aaaaaaatat ttgatgcctt atgtatctca attttcaaga
     9241 ccataaattt gtccctagtt aactttaact tattgaaata aatataatat tcgtgcgtac
     9301 tgatcctaat gtcacatcgc aaaaattccg cttcctcgct cactcagtcg ctacgctcct
     9361 gccgttcggc tgcggcgagc ggtatctcct ttctcaaaac cagagagatt cagatcatat
     9421 gatccgttat ttgatccttt ttggatcttc cactaagaag ccctgaatcg cgctctgccg
     9481 cttcgttcga tacaaccatg aggaaaacca tgcgaaatga aaaaaatcgc ttaaaatgcg
     9541 attcagagcg ttttagggag gttctgttag ttctcctgca ttgcgcccgt agttcgctaa
     9601 cgctcacacg cgcagtacag cgccccgcca tgctgcaatg caccagggcg gggtaaactc
     9661 gcttgcgctc gcgctaactg cggcattctg cggcgcaaat cagcataatc atggcctgct
     9721 ggtcagttgg gctttgcagg gtgaagggat ggcctgtgca ccctggtacg ttcgtcagcg
     9781 gctgcgccgc gcttcggggc gatgtggctc ctgtgctgcc ctggtatttt cgttcgcccc
     9841 ttccatccgc ttacgcggat taaaaaacgt gataacaatc acttatcgag taaaaaaacg
     9901 ggagaaaact tgcaaatacg acttaaaggt cgtattattg tttcatcgaa aggggaatgg
     9961 cccctctcac aatagcccag cagggcagga gattaaaaaa atgaatatcc aggaagcatt
    10021 aaacgttttt ggattatccg gcgaattaac tgaaaaagat atcaaagcag catacagaaa
    10081 agccgcttta aaatatcatc cagatcgtaa cccgttaggg gctgaactga tgaaagcggt
    10141 aaatgcagct tttgatgtat tgatggcaaa tattgataaa ataaatcagt tccagagcac
    10201 tgatgaacat gcacgatata attacggtga tgacctggaa aaagtattaa acgttctttc
    10261 tggtttatct ggtctggtat ttgaagtgat aggtaactgg gtctggatta gtggagaaac
    10321 cattacacat aaggaaactt taaaagaaat cgggtgtaaa tgggcggcaa agaaaaaaca
    10381 atggttttat cgtccagacg aacataaaag ttactggaat cgtgaagaac acacgataga
    10441 agaaatccgc gcaaaatacg gtacaaccgg acagcgcagg gcgacagggt ggcaacgcgt
    10501 ggaaaccaga gcgtaaccag aacgggggcg agaagccccc gatattatag ccagcccgtc
    10561 ttttggggca tcgaacccaa aaagacggga acagcagcca cgtagcaaaa agggaaacag
    10621 atgaactctt tttttgaaca atatcaccct gtctttgaag ttgtctgccg tatcctgggg
    10681 aacggctggc gcgtgaacaa acttgatgat tgttcgtctc gtataaaact gacgtcaccg
    10741 cagtttaaaa attactctgt gcatattcgg atggaaaaag accgcttttc tgtggtgggg
    10801 agtgtggata gtcgttcctg gcgtagtccg catcatgttt gcacgttatc cagaaaacgg
    10861 aatcccgttg atattgcagc cgatatcgag cgaaaaattc tggtaaatgc ttcgcaggag
    10921 gtgttacagg cgattgagta tgagaaacac caggtggaaa aaaaggacga aattctgatc
    10981 ctgaaaggta tgttatcgca acttgtccag cttgaaagct ggtatggggc attgacaggc
    11041 tttaaagctg aaaacggatt gaacggtaaa gtcaccgaac agggcgacag ttatgattta
    11101 cagattcggg gcttgagtat agatcaactt gttaaaatta cagggtattt gaaacagtta
    11161 tgagaaaaaa taaaggtgat gtgacttatt ttcttgaaaa agaaggtgac aattacaggc
    11221 ttacaaaaag gataaaagcc agaacaaatg ttaaaatcgg gaacaaaact acgaaaatta
    11281 cattgtatga tgctgtactg aatgagaatg aattacaaca tattgatttt acgtgtgccg
    11341 gattaaggga agacgatgag acgccagtta agaatttaat taaggagttt atgttaaatg
    11401 aaacccgata atacacctga aaatgtaaaa aaattacgtt taaaagcagg attaacacaa
    11461 aaggaatgca gtcatattta tggtgttggg ctaagaacct ggcagaaaaa agaggaagtt
    11521 aatactcaaa acagtcaaag tctgtcactg gttgagtttg agtttctttt gttacttgca
    11581 ggagaacatc ctgaatacgt gctctgcaaa agggagtcaa aataaaatga cctgtgatgg
    11641 ttttatatta gtacctggag ttgcgctcgt agctcgctga cgctcacacg cgcagtacag
    11701 cgccccgcca tgctgcaatg caccagggcg gggtaaactc gcttgcgctc gcgctaactg
    11761 cggcattctg cggcgcaaat cagcataatc atggcctgct ggtcagttgg gctttgcagg
    11821 gtgaagggat ggcctgtgca ccctggtacg ttcgtcagcg gctgcgccgc gcttcggggc
    11881 gatgtggctc ctgtgctgcc ctggtatttt cgttcgcccc ttccatccgc ttacgcggat
    11941 taaaaaacgt gataacaatc acttatcgag taaaaaaacg ggagaaaact tgcaaatacg
    12001 acttaaaggt cgtattattg tttcatcgaa aggggaatgg cccctctcac aatagcccag
    12061 cagggcagga gatttaaaat gaaatgctca tctgttttta cttcaaccac taatcatgtt
    12121 ttcacattcg aacgagtaac gctttgcact attatcctta tgcataagga tactggacaa
    12181 cagtatgttg tcatatttac tgataacaat aaaattcgtg actataaagc cggaattgtt
    12241 cctcagtttg gcgaacttaa gcagagtgat gttgatttag tccttttcta cagggacgaa
    12301 tatgaaaaat attttgattc attaaaagat ggcgatgaat gcttgagttt taaagatttt
    12361 attgagtgtc tttgttaagc attatgaatg caggggcatc cctgcatttt ctggaaattt
    12421 caatattgat tctgaaattg tctattaaca tcaatgcaag ggaaattcat gaaaacgtta
    12481 aaacaagccg caatgcagtt tgcatctgat ctgcgtaata atcgctgttt taaagctgct
    12541 tataatgatg ctctgttaga gcttgatcgg gaagatttaa acgccattgt acaatgcaca
    12601 tttctttttg agccaaaacg aacattagcc gaacttgata aattaattaa aaagatagaa
    12661 gtagaagaag attatgagtt ttgtgtatcc cttgataaag gtaaaggatt acacgaagtc
    12721 agaacattta aaagtgagcg tgaggcgttg gatgcttatc gcattttgac tctttacgga
    12781 tacacagtaa ctatagaaaa gaaggagggt aatgactgac tattcaaggt gtgatcaggt
    12841 tgttccacca acctgatcac gttatcgaca atcaaaactg aatgaggttt ttaaatgtca
    12901 acgcggcaga tcgtacagct tgctgattcc cttgtcaaag gctgggaaac cagaattccg
    12961 gcaatgaaat ttagcgaatg ggatcaattc cggtggtggt taaactactt gcaagggtat
    13021 gaaatgtttt aaataaaaaa aggggctttc tgcccctttg tattttttga caaaaatgcc
    13081 atgtgtaact ataattagtt gcatatctat aggggatgga tttatgggga aaacagataa
    13141 gctactggca aagtttttaa acagtaaaaa aacgtttgaa tgggatgaac tggtcgtttt
    13201 gttttcctct ttgggatatg tcaaaaagga aatgcagggg tcaagagtgc ggtttttcaa
    13261 tgctgaaatc aatcacacca tattaatgca tcgtccacat ccggaaagtt atatcaaagg
    13321 tggtacgctg aaagcaatta aacagaatct gaaagaggct ggattattat gaaacattta
    13381 aaatataaag gatatttagg cacggttgaa cccgattttg aaaataatgt cctgtatgga
    13441 aaactggcgt ttattcggga cctggtaact tatgaggctt ctacattagc tgaactggaa
    13501 caggagttta aaacatctgt tgatctgtat ttacagtctt gtgtggagga tggaaaggaa
    13561 cctgataccc cgtttaaagg cgtgtttaac gtcaggcttg atccagaact gcatcgtcgg
    13621 gtagcagaaa tggcgatgga agaagattta tcgttgaatg cctttgttaa taaggctctg
    13681 gaaaaagaag tcagcaatca tcgcgcaggg gcttaattgc ccttgttttt atgccctgta
    13741 agggcatggg aggcgctttg cgccggaagc cccgcagcgc agcgaggact taaaaagcgt
    13801 tacggcttca gccgtaacaa ttcccagccc tgccaggcct gttttttctt tcacaaatct
    13861 ttcagctata cgtttgcctg atggtcgaag acgaaagaat ctttcagcaa cgaaatctgg
    13921 acatatgcag cgacgatttt atagccaggc acagtgccac atatggtaca atcaatgcag
    13981 gatagacaat ccgatgtcaa atgttaacat ttgaatcaga ttgtccaaaa acgatgtttt
    14041 tgcctgtgcc tgccgcaggc tctgttgggg tgacttatga agatgatagc gttcaggcta
    14101 agtgatgatg agttaaaatt tgcagaacat aacgctattt taagtggatt taccagtatc
    14161 aatgcttttg ctaagcataa cgtgcttaat attgaaacca agcctgttaa catcccagtt
    14221 aataatgaac cagcaaagct ggtatcagtg cgtctttacc ctcatgaaat agaacttgtt
    14281 aaacgtaatg ctgctcttca cggcatgagc atgagcagag aaattgctat tcgtgtgcgt
    14341 cagtctttgt taaagagtga agtctgtctt taccctgatg aagttaagga acttaaaaaa
    14401 ctatcaactg ctgtagatcg tgttggtcgc aacattcatt ttatcataaa aggtgaaaga
    14461 ttctgtacgg ttaacgatcc agatttcaga aaagacgtta ttgaagtgat tgaactgtgt
    14521 aagcaaattg attcaaaact tgaaacgtta accaagagtg ttgttaacag atttgggtga
    14581 tttatgggtg tgtatgtaga acaggaatac cgtattaaac gcgctaaagg gactgggcgt
    14641 gatccgaaat ctcctaagtt atcgggaaga catatacatg ccagtaaatc ggcttttaat
    14701 cataaagtca gacatggtgc ggacaagaaa gcatatacct ggacacctac aaaagaagtc
    14761 acttttaaaa tcactggctc aggtaaaaca gccgcaggca tcaaaaatgg tattgattac
    14821 attacccgta atggtgaact tgaggcttac tgttatgatg gaaaaggttc agagcaaaca
    14881 gggaaaggag aagactttaa tagggagttt acttcaactt tatctaaagg aaatgattac
    14941 tccaggacat atcgtggaga aaacatcgat catgtgaaaa acatggtctt ttcaccacca
    15001 ccagaagctg gagtaagcag ggaagacgct ctgaaagcta cggtagaatt tcttaaagag
    15061 acttatccaa accatgcttt cgttgccgta taccatgatg ataaagaaga tcatcctcat
    15121 gtacatgtta atattaaact tcgtgatgaa gaaacaggaa gaagattaag acttactaaa
    15181 tctgaaacca ggaagttcag aaacggtttt catagaaaac tgaaaggtat gggatatgat
    15241 gttaccgcta cctggaaaaa agatcccgaa cgtaaacggg agattgagcg attacaggct
    15301 gaaaatccga aaagactccg gaatgtttac aaggtggtgg attttgggga gacttcatat
    15361 cagaataagg caggggaaaa acgaacacct ttcctcactt atgaaacttt aaaaggtgga
    15421 aaacaggtta cgatttgggg taaagacctg aaaaatcatt tcgagtctga aaagctccag
    15481 ccaggaacgc ttatcaaagt aaaaaaactg gctcctacgc ttgtacgtag tccaatgttt
    15541 aatgatgatg gaactgttgc aggctacagg gaaacgcatc gcaataactg gcagattgaa
    15601 aatattgccc ttgagcggaa cagagaacgt caggttcatg agcgtgaaac caggcagccg
    15661 gaagagagcg acgttaaaaa gcagctatcc agaaaacatg agcaaggtca caatatcggg
    15721 tttgctcttg aacacgggtt tacaaaggat tcagaagaac ataaaaaact aagaatacag
    15781 caagagagga actggaaagg cctgggattt taatttgatt ttggcgcagg tgaacaaagc
    15841 ggctactttg ctcacctgct gatcacaaca acctacgagg gaggttatca tgactgagca
    15901 tgatgctatc tgcatttctg gacttcatca aatttttagt gatgaagaac atttgagtga
    15961 gcaacaaaaa gacattattc tgatgtacgc ttatggctat accctgaatg aaattgctga
    16021 tttcaaagga ctaaagcctt caactgtcag aaaatatctc gattctgtaa gagctgaact
    16081 gggaggtgtc tcgttggcag ggatcagaac actggtactc attcggacta atgcccttct
    16141 cgtgtcaagt ctttccagga tcagtgagag ggggaattta tgaaaaaata tctgcttttt
    16201 gctttgccgt tcttcgttgt tggttgtagt gaagaagtaa aaagtgtgga ttggtggggg
    16261 cagcatctta cggaagctaa acaaaagcag gcagagtgtg agaagtctgg ctctgattct
    16321 cagaactgta agaatgttaa acaagcattg tttattcagt ctcagaagga tgctccagtc
    16381 cctacattcg attaactaat gtttcaatca tactagagcg cccatatggg cgcttttttt
    16441 tgcatgatca cacgaatcat aatatgacca ttttgtcaat gttatttgat cgtattgttg
    16501 agcattgtta ttttgcgaat catgttcgca tctaaaacaa atccaaaaca cacttatagt
    16561 ggattgatta aatgaaggag aaatcagata agtcatcgga aaaaggggtt tatgtcacga
    16621 taaaactcga tcccaggttg aatgcattta tcgaagagaa aacgaaaaca tctttgctta
    16681 gtaagaggaa gcaaattatt tacttattaa tgcagagtat gcgtattgat ggatatatgg
    16741 agcgttagct atggcgtctt tattcccagc cttgttgctg tgtgcggcgt cagttcatcc
    16801 ggatacgata aatgatattg cacgggtcga gagtggcttc aatccttatg ctgtggctga
    16861 aattattcct gaaagggaac gcggtagcta tggcaaaagt gttatcagtc atatgcccaa
    16921 aagtaaggag gaagctctaa cagttatcag agaaattgaa aacagaaaaa gacgttattc
    16981 tgtcggattg atgcagatta ccagcagtaa tttttctttt tattccacgt ccgcagaaaa
    17041 actccttgat tcgtgtgaaa acttgtctgt tttcgaaaag attatcgtgg attgttataa
    17101 acgagggagg agcctggaga atgcgcttag ttgttactat acaggaaatt ttagtaacgg
    17161 taagcgaaaa gaaaaagaat ttaataatac aagttatgtt gagcgaattg gttatacagg
    17221 gaacgaaaaa aatatgttgt accaggtaca agaagcaacg ggggagaaca gcgaaaaaat
    17281 cgttcacaca atgcgtcagt tatctggccc gaaaccattc tgaaatctgc ttttgttgat
    17341 aactcacatc caacaaaagt tattaattaa caggacttat aaaatgtcat ttaagaaatc
    17401 agtatgtaat cgtatcagtt catctgtcac tgctgtaatg cagcgtaaaa ataaggtagt
    17461 tatggcagtc gccggggcaa cagttgcatc accggccttt gcggatggat tttcaaaagc
    17521 ggaaacactg ctggaaaagg ttaaaacagg gcttagtggc ctttcactgg tcacggtgac
    17581 tattgcctgt ctgtgggtcg gctacaaggt tctgtttggt ggaagcacga ttcgtgaatg
    17641 ctcacctatc atcatcgggg caattgttat cgccagtgcg gctgaagttg catcaatgat
    17701 ggttaactaa taaagcgggg acgatagtat gtctacactt tataaagcga tgacacgccc
    17761 tgctatgtat gtgggtgttc ctgtcgtccc tcttactgtg gttgcagggg cgttatttct
    17821 ggcgggggtt tatatcagca agctgatctg gctggctatt cctgtcgcgg tttttgttct
    17881 cagaatgatc actaaacagg acgaccacat ttttaacctt tactttctta agctgaaaat
    17941 gctcggaaac tcagtgtgta atcgtttttt tggcgcacga gcgttcctct ccggacaata
    18001 tgaagctgtt gaaattgatg agtttgttaa tgccatgaaa ctgaatgagc gaatcactac
    18061 tggtaaatat ataccctatt caagccatgt tgataaaaat attgtcaaaa caaagaacgg
    18121 tgattatgta gcgacatggc aactgatggg gattaacttt gagtcaatct ctgcggagat
    18181 gttagaaact attgactcac aggttgccac tcttgttcgt tcattttccg gactgcccgt
    18241 ttcattttat aaccattcat gcagggcgag tttttatgat gcctttacca caaaatcagg
    18301 taataaatat gctgatataa tatcagattg ttactatggt tcgatgaaga aaaataaatt
    18361 caaggggaac actctttact ttacgctgat ctacagacca gatgggcgtg tagaaaaact
    18421 ggaaaaacgc aaaaaaagta ttaaagaaaa gaaagatgat attaacattc atgtgaagag
    18481 aatgaatgaa atgattaata cattctctgg cgctcttgat aaatttacct gtaaacttct
    18541 tggtatgtat gaggagaacg gaaaggtatt ttcttctcaa ctgtcattct ataattatct
    18601 tctgacaggg aagttgcaaa aaatcagagt cactgattct ccggtgtata acgttcttgg
    18661 tggagtggat gtatttttta atcatgatac cggacagata tgccgcattg atggaaataa
    18721 attctttcgt tctattgaaa ttaaagattt ctgtagtgag actgcatccg gtgtttttga
    18781 tgtgctccag tattctgatg ctgactatat tattacgcat tcatatacat ccatgagcaa
    18841 atcagaagca ttgagtacca ttaaacgtgc ggaaaaacag ttaaagagta cagaagatga
    18901 tgcggttact caattgcagg aactggaaaa ggcaaaaaat gatattgtgt ccggtgatat
    18961 atcctttggt tactaccatt tcacgctaat ggtaatggcg gacagtatca gggagcttga
    19021 cgaatctgta agtaaaatta cggcagactt tactgacctg ggcattattc cggcattgtc
    19081 aaccatgtca ttgccagcgg catattttgc ccaacttccg gcggtttttc atttaaggcc
    19141 gcgtttatct ccggtatcga atgtaaattt tgttgaactg gcatcattcc ataatttcta
    19201 ccaggggaaa cgcgataaaa actgctggac agaagcggtt gctattctca aaacaccaag
    19261 caaacaggcg tattatctga atttacataa ctcagtactg tttaaagatg aaacaggtga
    19321 aaagaatctt gctaatacta aagttatagg aacggcgggt tcaggtaaga caatgtttct
    19381 gtcatatctt gcctgttcat tacagaaata caataacccc gaaacttttg ctgattctgc
    19441 aaaaaataag aagttaacgt gtgtctttct tgataaggac agaggggctg aattatgtat
    19501 ccgaatgctt ggtggggaat attacaccgt aaaaagcggt gagccgacag gatggaatcc
    19561 ttttgctctg gaggcaacaa aacgtaaccg tatttttgtc aagcaactga tggagattct
    19621 gtgtaccaga aatggtgaaa gattatcgac aagagaaaga ttgcttatta gcgaaagtgt
    19681 tgatgctgtg atggattttc ctcctggcga aatgcgggaa tatggcatta ccagaatgct
    19741 tgagcatctt atgcagagag atgatcggga tgagcaggag aacgggatta tccttcgttt
    19801 gtcccaatgg gctaatggtc aggctcatgg ctgggttttt gataatgcta aagacacatt
    19861 caatattcag catgtcaata attttggcat tgatggcacc gagtttcttg atgatccgat
    19921 ggtatgtgca ccaattactt tctatctgct gtatcgcatt acgcagcttc tggacggtcg
    19981 gcgtcttgtt atcttcctgg atgagttctg gaaatggcta caggatgaag cattcagcga
    20041 ctttgtctat aacaagctga aaacaattcg taagctgaac gggctggtta ttccggcaac
    20101 tcagtctccg gatgaaatac tgaagaataa gatttcacgg gctgtggttg aagtatgcag
    20161 caccagtatt tatctggcta accctgatgc cgattacaat gattatgtgg aagggcttaa
    20221 gctgacacca gaagaattta atattgttaa aaatcttgat ccaatgtcga gacagttcct
    20281 gattaaaaaa agcagtctta aaaaggggga tggtaaatca ttttcagcac ttgcgacact
    20341 cgatttatcg ggacttggtg gatatctgaa aatattgtct gccagtgcag ataatctgga
    20401 aatttttgaa agtatttatc atgaaggaat ggagcctgat gactgggttc ctgaatatct
    20461 cgaacgggca atctgacagg tgaatttatg aaacgtgtaa aaacattgat gctgatatca
    20521 ttattgacgg cttcatttta tagtagcgca ggaattccgg ttgctattga tgccagtccg
    20581 gaatgggctg ttgaagccgc aagatggaca gaacgactca aacaatggtc cgaaactgcg
    20641 caacattatc agagtcagat tcaggcatat aaagaccagt tagccacggc aacaggtata
    20701 aggaatattg cggcattcac aaatgaacta agtaatctac aatcagaact gacaaatatt
    20761 tataagcagg ggaacagtta tatttctgat tttaccagta atcccgaagg tgcattgagc
    20821 agccaggcta aaaatctgtt cagcaagtat ggagccttcg atatgtgtaa tacgggctat
    20881 gaacgtaatg ataatctctg taaagcacgg attgtgtcaa cggctgccag tattgaacag
    20941 ggaaatgaga tcaataagca gttatcaagt gcaatgtctc agattcagag tttaagtagc
    21001 cgaattgagg cttcaaagga tatcaaagaa tcccaggatt tggctaacgc attacaggcg
    21061 cagtcgttaa aaatgcaggc gataaaaatg cagtatgatg tctggaataa taaaaataaa
    21121 gcagatcatg agatgttggt cacacaagaa caagaggcct ttattaaaca gcagaaagaa
    21181 gctgaaccat taacttttga ttaaaaggtg gatatatggc tcaggggttt ttcgttaaat
    21241 ataattctac cgttatggat tcggtagata aaatcagctc cagttatcaa acacaatttg
    21301 ctaatgatat tatgtcgtta gcaacggtat cggttacgtt atatgtacta tggaaaggat
    21361 atcaaatact tgccagtaaa actcagacgc ccttgcagga tttagtatgg gatctatcaa
    21421 aatttgcaat cataatcatg tttataacta atgcggatgg gtatttaact gcggctactg
    21481 atgcgttgca aggcatgaaa gatggttttt ctggaggggt gagtgtctgg caaactttag
    21541 ataacttatg gaaaagtacg caaaatcttg gtgcggaaat atactcttta gataaatcaa
    21601 catatgttaa agatcaaggt gtagttggtc agtttttaat atggactggc tcgcttattt
    21661 taatggctgt tagtgtggtt gtttttttaa cagcagatgt aacgatgaaa ctcctgatta
    21721 ttacagcacc gatatttatc ttttgtctca tgtttggttt tattcggagc atgtttaata
    21781 attggttaca atcgttattc tccagtattc tgacagttct atttgccagt ttagtgattc
    21841 ggatagcaat ggattttcaa gggatgatcc tttcccatgc tattcgtgct gcacaaacag
    21901 ggaatgtaaa tcttgtatct acaggtgcta tgggctttat ggctgggttt ttgggggctt
    21961 tattggttct tatagctaaa ggttttgctg tccagttagc aggtgcaggt gttgaaggtg
    22021 ctgttcaggg cgcagccatg atggggctgg gtgctgctgg tatggctact ggtaagtctc
    22081 tgatgcttgg cggtcgtgct ggtttaggtt ttggcttagg gatggccgga agagcgggca
    22141 tgaattcttt atcagggaaa gcagggaatc tgatggggcg tggtgcgcga acagccgctg
    22201 aatgggcggg tgaaaaggga tatcaggcgc tggctccgac aggtgctttg gggatgaagg
    22261 cgagaagact tgcatccctg gaaaaagcac gagcgaggaa cgccgcatga aaataatgaa
    22321 acgttttttt tatgtgatgt ccctgaactg gatactggtg ttcgttgata aacatatcac
    22381 ctccggatgg agcaggaaga gaaagctaat aacccagctt gttattttaa tcacgggaat
    22441 taccttattt aaggtcttag gtggaatcag tcagagctgg ttgtgacatg cttcattatt
    22501 ttgtcatgat actttatttt gtcctaatcc ttcttttagg agtgtttacc tgcttcgcag
    22561 gaataagact tggtttaggg cttgcgggga aatggagaaa gggtatggat cttcgctttt
    22621 tgcttcttat tggtgggatt ctttttcttc atcttggcct ttatctctta aaggtgttcg
    22681 tgaacgctta ataaggtgaa tttatgcgat gtgtgattct tttgtttttc ctgtttcaga
    22741 tttccggatg taccacaagg aataaccttc cttctgatgt ttccggcgaa ctggaaccca
    22801 ttaaccacag ccaggtaatc agttatgagt gaaaaaatcg aaaagaagat tgagacagct
    22861 aaatccttcg aaagacaact ctatgcagaa aatgaacggt ctaagaaaaa tgcatggcgt
    22921 gttgcagtgg cagcatcatt actgtcctta tgtcttgggg ctgcaatttg tgttcttgtg
    22981 ccattaaaag aaaaagagct tgctattgtg gctgttggcg aaaaaacagg ccgtacagaa
    23041 ctgattactc aggttaaaca ggaaaagatc ctgcaatctg aagcacttgg gcggtatttt
    23101 gtaaacacgt atattacttt acgtgaaggt tataattatc cgtctcttca gtatgattat
    23161 gagactgtac agctatatag ctcgaataca gtaaaggacg attatcttcg tctgtataac
    23221 agcgatatgg ctcctgataa aatttatcat aataacggtt cttacgttgc ggttgaggtc
    23281 atctccaata ttatttctga cgcaaccgcg ccagataaac tggcctctgt gcgctttaaa
    23341 aaaacgacga gaaacttcac gaccggacag gtttcagttt catactggac ggctcgtgtg
    23401 acatatcgtt ttgaaccaga aaagtcggtt aaaagttcca gtcgtgagct taatcctctc
    23461 ggttttactg taaccagtta ccagacagat cgggaagtca ggggggaatg atgaagaaat
    23521 tatttattgc tacatgttta ttgcttcctg ggcttgtgta ttcagcagcg actccgttac
    23581 cttctggatt tgatgcaagg atgcagactg tgagttataa cggtgcgaat acgaccgtta
    23641 tccggtcaaa gacaggattt ctcacatcag ttgtttttga tgaaggtgag gctgttatca
    23701 gtgcaaaggc tggttttcct gccggatggg aaatcacaac cgatgataat gttgtttaca
    23761 tcaatccgcg tcccgttgtt caggaacagg aaggcgatga aggcgaaaaa ctgaaaaagg
    23821 ttttccagcc aacagaaaag gaatgggata cgaatctttt tgtcagaaca acaaagcgga
    23881 tttacagtct ggatctaatc cttctgtcag aagaaaaaca agcgcaacct gcttatgttg
    23941 tacaattccg ctatccatca gaaatagcga aaaagaatgc agaagaagta aggctggcaa
    24001 aagaaaaaca ggaaaaactc agacagaaga aactgatttc tgaaagtttt gaaaaagccg
    24061 atgcgcctaa aaactggaat tatttcatgc gagtcaatga aaaatatgac agtcgtcgta
    24121 tcgcccctga ttttgcttat gataatggca tatttacctt tttaggtttt aactcaggga
    24181 aagtattccc agctccattt gctgtaagag atggtcagga acagacactt gcttttaatg
    24241 tggaaacaaa aggcaagtat aaaattatgg ttatccacaa cgttaatgac aaatttgttt
    24301 tacgctatgg aaacagcgtt gttggtgttg tgaataaatc tttcggaaaa gtattaaccg
    24361 accagaggaa tacatcttct cctgcggtag aacgtgttga ggtgaataat gactgatatg
    24421 aaaaaaacag atgatttagt tgatgatgcg aatcagtcaa agctggaaag taaacccgtt
    24481 catgatatcg gtgatatcag gaacaaaaat aatcgtatgc gttctggctt tctgtttggt
    24541 ctgatggctg tattagttat tggtattttt gcgctgaaaa catataaaaa ttattttgca
    24601 gatgaccagc agaaagcatc agaatcaaca ggcgatacca gcatttctca ggtaagtaaa
    24661 atccgtactg gtcttggtca gaattttgac cctgttgaga acaaagcaat tatcaatcca
    24721 ggcgctactg gttctggtaa tactgtttct gacggtcata aagaagtgcc acaggagggg
    24781 ttcaggaaat atttgtcaat acctgttgct ggtcagggag ggagtcagac tggcgcgagt
    24841 ggcagcagca ggacatcgca gacatcagag ccacaggaag aaaggaaaga atcaaaagaa
    24901 aatgtgcctg gtaaatcagg aatgaaagta actgcgatta atctcgatcc tgatctctat
    24961 attgaggaaa acaggcttat accgtgtgct ttaaccacac gctttgtttc tgatgttgca
    25021 ggtcgtatca gttgtgtttt tacagaagat gtatggagtg ctaatcacca cacaaaatta
    25081 ctggaacagg gaactaaggc ttttggtcgt taccagaccg gaacgctgaa tcatggacag
    25141 ggcagaatgt tcgttatgtg ggagcagttg cggacgcctg ataataaacg aatcgatatg
    25201 gtaaatacag cagcagctgg tcccctggga gaagcgggca ttgatggatg gatcgattct
    25261 cacttctggg agcgttttgg tggttctctt atgctcagta tggttcagga tgtagcggcg
    25321 gcggcggcgg ataatgcacc tggtaaagat cgtaatgtgg attataccga aaactcacga
    25381 caggcaatgg ctgaaatggc taaagtcgca cttgagaatt cgataaatat tcctccaaca
    25441 atgtataaaa accagggtga cataatcact attatggtcg gggaagacat tgatttttct
    25501 gatatctatg agttaaaggt aaaatagtat gagtggcgtt attcctgtca gcattagcaa
    25561 taaatcgctc gatttttata aaaatcaagt attccagtct tttcttgata ttgaagggct
    25621 aacagaaatt gctgtcaacc gtcctggtga aatctggacg gaaattaatg gtgactggac
    25681 attccataat aatgacagtg tgacctttga tttttgtaaa cgtttttctc atacgctggc
    25741 atcatttcgg ggagatgaaa tcggcgagac caagccatta ctttcagcaa cactggaatc
    25801 aggagaacgt gtacaggtcg tttttcctcc tgcatgtgag agaaatacta tttcaatcac
    25861 tatacgtaaa ccatcgacac ggcagataac acataaagaa tatgtggcga acggttttta
    25921 tgattatgtc cagtcaggaa aaaaacacag gacatacgat gatgagcttc ttgatttatt
    25981 cagagcgaga aatatcgctg cttttatgga gcttgccgta gcagcaggga aaaccattgt
    26041 atttgccgga gcaacgggtt ccggtaaaac aacttatatg aagagtctta tcgatttcat
    26101 accattgaat acacggctga ttacgattga agatgcagag gaaatcaaat tttttatcca
    26161 taaaaattat gtgcatcttt tttacccttc ggaatccggc agtgattccg gctctatcat
    26221 aacagcagcg aaattaatca aatcctgttt gaggatgaaa cctgacagaa ttttactggc
    26281 ggaaattaaa ggtggcgatg cctgggattt tgtgaaagtt gctggttctg gtcacagtgg
    26341 aagcatgacg tccattcacg cggcctcggc aaaagatgcc atcattcaga tggtgacaaa
    26401 atgttatcag aacagagaat gtcagaatct tccttttgat gttcttcgta aaatcattat
    26461 ggacagtatt gatattgttg ttcatgtagg cagggatggt gttgtcaggc atatgagcga
    26521 catctattac aaaggggctg aatgtgaaaa cttttaataa gtcgcaatct gtttttatat
    26581 tcgctgttat gcttgttgcg gcatggtttg caggttcatt tattttcttt gtgctttact
    26641 tcagccagat aaagaatctg aaaccattga aggctgtgtt cagatccatt gatgcgtaca
    26701 ggatggatat ttttacagac agccttactt tatctgttgt gactacggat atcagagttt
    26761 tagcctttgt tgcacttgga gcaggatttg tcgtgtctct tatcatccct gttgcggcgt
    26821 tgataaaact gaacgagaag aaagaaaata ttttcggtga tgcgcgattt gcaacaatta
    26881 atgatattcg tgagtctaac agtttcacgc ttgacggtga cgaaaaagac gggattatcg
    26941 ttggtataaa agacaagaaa atcatacgct atgtgggagc agcattcagt gctatgggag
    27001 ccggaacaag ggctggtaaa ggtgctggta tagtcatcac taatcttatg aagtactggt
    27061 ggagtgttat tattctcgat ccaaaaaggg agtgttttaa tatcaccagt cttatcagga
    27121 aggtgatttt aggtcatgag gtttataaat ttgatccctt tagttcggta acgcaccgct
    27181 ttaacccttt gtattatgtc agcatgggaa cgagtgaagg ttttaatcag cttgaaaatc
    27241 tttcgttgat tatttacccc tataagacag atggtgcgga tgctggtagc tatcttaata
    27301 agacggcggg tggtgttttt aaatcttatg ctgtcgcttt atggtttatg attaagaatg
    27361 ataaggctgg actaaaaacg cttgatattg agcctgtctt ctcaatgtct aaaattaatc
    27421 agctttttga gcgtgcagaa cccgaacatc ttctttcatt catgaatgat attcgttcag
    27481 aattaagggg gaaagacaaa acgcttgctg atattggtgt cgctggcctt aaggcattca
    27541 ttgagatgga ggataaaaca aaagcacaac tcaaaagcaa ctttcttaat ggattatcac
    27601 cgtttgctaa ccccaatgtg gcaaatgcta ctgatggaaa tgattttgat ttgcggcagg
    27661 tgcggaaaaa gcggatgaca atttatttct gtatttctgg tgataatgcc aggttggctg
    27721 aaaaaataac aaatattttc tttcagcttg ctatacaggt gaatcttgaa aagatgccaa
    27781 cggatgatcc ggaaataaag catgactgcc tttttctact ggatgaattc ccgtcaattg
    27841 gtgctgtaga ttacatcaag agtaaatctg gtctcattgc tggttacaag ctgaaattgt
    27901 tgattgttta ccaggtcggc tctcagcttg aggaaatcta cagttatgca ggcagtaaaa
    27961 cattactggc aagtgcaccc tgcaaaattg tttattccgc ttctgatgtt aaagatgcgc
    28021 gggagttatc agaagcgatg gggacacgaa cagtaactat cggttcgaaa agcaaaagtc
    28081 gtagtcgtgg aggaacatcg agatctgaat cagaaagcct tattgagcgt ccactggtaa
    28141 caacaaatga actacttaca ctgaaattta gtgaagaaat cctggcaatg aagggagaaa
    28201 acccgattcg ttgtgaaaag gcattctact atctcaatga gtatttcttt ggtgactttg
    28261 tgaaggttgc tccggaactt gcaaacattt tccccaggaa gaaaggaaag ctggttatgc
    28321 ctccacagaa agtatttgaa aatgaaatcg tcgcaaaagg gtatctggta gtaaaagatg
    28381 ttcctgatct cgataaagcg gcataaagga gaacatgatg aagaagttag tgtttttatt
    28441 gatttccatt cttgctggtt gttcatcacc gccagagcca acacccgtgc agtttgaaaa
    28501 ggcaaatgaa gtgatcaatc cctcattgcc atatgtcccc gattttcacg gtgtcataaa
    28561 gtcagacgtt agcggtaaag gatgggttta tgagatcact tccttatccg gagtacaggc
    28621 cagaacgccg acgttttatt acgctctggc tcatgcggac aggattgtag tgacaacaca
    28681 tgatgctggg ctgtggtttc gaatcagaga tctgttgaag atggaagggg caacagcagt
    28741 cgtggaatgg cgaaacgaga aaagtttttt acctgaacag gtaaaaatag ttttcattaa
    28801 agcacaaaat gaggtgaaaa atgactggaa aaaatagagt ggttttacca gccttgctgg
    28861 cgttaggatt aatatcaaca aatgctaatg catctgaccc ttgcgcttcg gtactttgct
    28921 tatatggaaa agcagtcggg caaggtggag ggagtgaatg cagaagtgct gaaaaggatt
    28981 tttttaatat tctgaaaaag aaaaaaggaa gcattcgctg gagtaaaact tttgatgccc
    29041 gtaaagcatt tctgaatcag tgttcaacgg ctgatcctgc tgctatatca aaaatcatga
    29101 gtaagtttgg tcgtgtcaga ggttaattaa aacctgataa ccgcgccaac gggtatcagg
    29161 gtactgcaag tatcacattt cgcgccaacg aaatgtgatg attagttaca atcactgagg
    29221 ttagaaatga aagtaaccaa atctattata gctattttat tgtgcttatc tgctggtagt
    29281 gcataagtgg atgtaataaa aaatgctcgt gcctttttga aaggaaccct cgatctgagc
    29341 gttcaggaag cagatgaaga tatagaggaa agggaagaac tttataaaaa gaacggggca
    29401 caacctgact atttaagtta cctggaggat taacacatgc aatatgcatt gtttgatgga
    29461 tttgaacgaa agtttttgct ggatgctctt gaattcggtg ttctgaagga ctggaaagaa
    29521 aatccggtaa aagaacttcc tgatattgat gaatctgctc accccttcca tatctgttat
    29581 ggtggatatt tattaaaccc tggtgtttca gattcagata ttagcagaaa aataaaagac
    29641 caggcaggat tctggctggc agctattgat gatacccgca tggattgtca ttcaatagct
    29701 tattatgata ttcacacact ccctctgatt tcgtgtggtc atcaaaagat agttcctttt
    29761 gccgcgttaa taaaagctga tgaatgcatc atttcaaaaa ttgcttcgta ttctggtttt
    29821 gctgtaacag cctttttgag aattaaagag tgggatattg caactaatat acttaaccgt
    29881 gagggaattt ttgcctttaa tggctgtgag cgcagattca gagtagtaag taaagataac
    29941 tggcaacata cagtatcgga agaacgcgct atccgttgtg ccaaaagatt aattcaatgt
    30001 aaaggataac aaaatgagac tttttatcgc agaaaaaccc gcagtagcaa atgatattgt
    30061 taaggcactt ggtggcaatt ttacccgcca tgatggctgg tttgaaagtg ataacgccat
    30121 tgtgactaac tgttttggtc atattatcga atcacaaccg ccggaaaact ataatcctga
    30181 atacaaagcc tggaaggttg aaacgcttcc tttacgtctt tatcccgtga agtatcagcc
    30241 tgttgaaagt gcagcaaaac aggttaaaac gattctcgaa cttatcagac gtggagacgt
    30301 gactgaaatt gttcacgctg gcgatcctga tgatgaggga cagctactgg ttgatgaagt
    30361 cctggaatat gcaggcaaca caaaacccgt aaagcgcgtt ctgattaacg acaacacgct
    30421 tccggcagtg aaaaaggcac tggcaaatct taaagacaat cgtgatttca aaggacttta
    30481 ccttaaggcg ttggcgcggt cagttgccga tgccgtctat ggcttctcta tgacacgtgc
    30541 gtacaccatt ccggcaaaag ccagaggata tcagggcgtt ctgtctgtcg ggcgcgtcca
    30601 gactcccgtt cttggcctga ttgtgaatcg tacccgtgct aaccagaacc ataaatccag
    30661 tttttactac accatgaccg gagtctttca gcgtggtgct gatgttatca gggcgaactg
    30721 gaagccaggg gaatttgctc cgctgacaga ccgtaaatta cttgataaag cgtgggcaga
    30781 cggaacggct gcatcccttg caggaaaacc ggctacagtt gaagcagcag caactgatga
    30841 taaaaaaacg gctgcgccgt tgccgtttaa tctggtcaga ctccagcaat acatgaacaa
    30901 gaagtttaaa atgacggcac aaaaaacgct ggatattacg caacaactac gcgaaaaata
    30961 taaagcaatt acgtataacc gctctgactg ctcatatctt tcagatgaac aattcagcga
    31021 agcgccgcag gttatcgatg ccctgaaatc agtctttcct cagtcgctgg atattgattc
    31081 tgcacgtaaa agcaaagcgt ttaacagtgc aaaggtgact gcgcatactg cgataatccc
    31141 gaccgccagt gtgcctgatg ttaacgcact cagcaccgac gagcgcaatg tttacctggc
    31201 gatcgcacaa cactatcttg ttcagttcat gcctgaaaaa gcataccagg aagtatcggt
    31261 tgccattcag tgtggtgatg agtcgttcta tgcccgtgcc agaaaaacaa ctgacagcgg
    31321 atttgaggcg tttcttggcg cggaaaccac agacgaaggt gaatcagaag ataatgatga
    31381 ttccgctttt gaactgctct gtaaaattcg cacaggagaa acactgacga caaaagaagt
    31441 tattgttaat gagaagaaaa caacaccgcc gccgttattc accgaagcct ccttgcttgc
    31501 tgcgcttgtt cgtgtcgcgg attttgtcac tgatccaaca attaaaaaat tgttgaagga
    31561 taaggataaa gacaaaaaag atgaacatgg tggcattggt acgccagcta cccgcgcagc
    31621 cattctggaa acgctgaaga aaagaaacta tatcacgctg gaaaaaggga aacttattcc
    31681 tactgatacc ggatatgcgc ttattgatgc cctgcctggt atagcggtta atcctgatat
    31741 gacagcatta tggtctgaaa agcaggctgc catagaaaat ggcgacctga cggttgaaca
    31801 gtttattaat gatctgtacg gtgaactgac aggcatgatt tctgatgttg acctgggcga
    31861 gatgaagatt gaacccgctg cgccagcagg gcagtttcaa cgcctggact ctccctgccc
    31921 ttcctgtggt aaacatattg ttatcaggcc gaaaggttat ttctgtaccg gatgtgaatt
    31981 taaaatctgg agtgagtttt ctggtaagaa aatcacccag gcacaggccg aaaaactggt
    32041 taaatcaggg aaaaccgatt tgattaaggg atttaaaaag aaaagtggtg gaacgtatga
    32101 tacagttctt gtccttgagg ataagaaaac agggaagctg ggttttccgg caagggctaa
    32161 gaagtgaaaa caaagcagga atggcttttt cagttaagaa aatgtacatc aagagatact
    32221 cttgaaaaag ttattgagat taaccgttac aaactgcctt tatcagaatc agaggcattt
    32281 tattctgccg cagatcatcg ccgagcagaa ctggtgatga ataaacttta tgataaggtg
    32341 ccttccggcg tctggaagta cgtacactaa ataagaggat taattatatg agcgaactga
    32401 ctaaagaaga tgaatacggc attatcagcc gtactatgat gaatattcgt tcattgcgtg
    32461 tttttgcccg tgagattgat tttgagcagt tgctcgaaat gcaggaaaag ctcaacgttg
    32521 ttattgaaga acgtcgtgaa gatgctgaac gtgaagcggc tgaacgccag gaacttgaag
    32581 ccaaacgtca gcaggccatt gaatacatca tatctttagg tcttgatccc gaatcactcc
    32641 ttgctcctgt aacagcagat acagtaaaaa ccaggcggaa agccaaaggc ggagtaagaa
    32701 aggctaaata ccgctttaag gatgaaaatg gcgagatcag agaatggtct ggtaatggca
    32761 agcgtccgct tgctttacag aagctgcttg atgaggggca tttcatggaa gatttcctca
    32821 ttgagaaaac taagccggaa caggcagaat aacccgccaa gtatacatca cacagggcac
    32881 tgttgcaaat agtcggtggt gataaactta tcatcccctt ttgctgatgg agctgcacat
    32941 gaacccattc aaaggccggc attttcagcg tgacatcatt ctgtgggccg tacgctggta
    33001 ctgcaaatac ggcatcagtt accgtgagct gcaggagatg ctggctgaac gcggagtgaa
    33061 tgtcgatcac tccacgattt accgctgggt tcagcgttat gcgcctgaaa tggaaaaacg
    33121 gctgcgctgg tactggcgta acccttccga tctttgcccg tggcacatgg atgaaaccta
    33181 cgtgaaggtc aatggccgct gggcgtatct gtaccgggcc gtcgacagcc ggggccgcac
    33241 tgtcgatttt tatatctcct cccgtcgtaa cagcaaagct gcataccggt ttctgggtaa
    33301 aat
//
