LOCUS       NZ_MF175191            33660 bp    DNA     circular CON 18-MAY-2024
DEFINITION  Escherichia coli strain CDF8 plasmid pCDF8, complete sequence.
ACCESSION   NZ_MF175191
VERSION     NZ_MF175191.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14227700
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33660)
  AUTHORS   Zurfluh,K., Nuesch-Inderbinen,M., Klumpp,J., Poirel,L., Nordmann,P.
            and Stephan,R.
  TITLE     Key features of mcr-1-bearing plasmids from Escherichia coli
            isolated from humans and food
  JOURNAL   Antimicrob Resist Infect Control 6, 91 (2017)
   PUBMED   28878890
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33660)
  AUTHORS   Zurfluh,K., Nueesch-Inderbinen,M., Klumm,J., Poirel,L., Nordmann,P.
            and Stephan,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAY-2017) University of Zurich, Institute for Food
            Safety and Hygiene, Winterthurerstrasse 272, Zurich, Zurich 8057,
            Switzerland
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: SMRTanalysis v. 2.3.0
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009976965.1-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 01:32:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 42
            CDSs (total)                      :: 42
            Genes (coding)                    :: 40
            CDSs (with protein)               :: 40
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 2
            CDSs (without protein)            :: 2
            Pseudo Genes (ambiguous residues) :: 0 of 2
            Pseudo Genes (frameshifted)       :: 0 of 2
            Pseudo Genes (incomplete)         :: 2 of 2
            Pseudo Genes (internal stop)      :: 1 of 2
            Pseudo Genes (multiple problems)  :: 1 of 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MF175191.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33660
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="CDF8"
                     /db_xref="taxon:562"
                     /plasmid="pCDF8"
     gene            7..873
                     /locus_tag="HTN63_RS00005"
     CDS             7..873
                     /locus_tag="HTN63_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473366.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001353743.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGVKDYKYPDYPAF
                     KRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFD
                     KMYPPEN"
                     /name="replication initiation protein"
     gene            886..1290
                     /locus_tag="HTN63_RS00010"
     CDS             886..1290
                     /locus_tag="HTN63_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            1425..1952
                     /locus_tag="HTN63_RS00015"
     CDS             1425..1952
                     /locus_tag="HTN63_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(2104..2343)
                     /locus_tag="HTN63_RS00020"
     CDS             complement(2104..2343)
                     /locus_tag="HTN63_RS00020"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_236918848.1"
                     /translation="MYLKSKNGRIGYYGTVFSVEFQSDDSSTWKLPIGTALLTPIGQEL
                     MKICGSTPDIAYLNKFLNKINVEGSQVKLSIINM"
                     /name="DUF2806 domain-containing protein"
     gene            2524..4149
                     /locus_tag="HTN63_RS00025"
     CDS             2524..4149
                     /locus_tag="HTN63_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     gene            4221..5015
                     /locus_tag="HTN63_RS00030"
     CDS             4221..5015
                     /locus_tag="HTN63_RS00030"
                     /inference="COORDINATES: protein motif:HMM:NF028536.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_280956991.1"
                     /translation="MPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVADWFYLGMG
                     HWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKWLVPVTKFR
                     VRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRNTIPDKCFP
                     AAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSHTVVSMMLA
                     WAMSAGLAWVFFKKGEQFKVRNFSCTKLKYSGCSNLRCALLF"
                     /name="PAP2 family protein"
     gene            complement(<4943..5212)
                     /locus_tag="HTN63_RS00035"
                     /pseudo=""
     CDS             complement(<4943..5212)
                     /locus_tag="HTN63_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012478345.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(5242..5916)
                     /locus_tag="HTN63_RS00040"
     CDS             complement(5242..5916)
                     /locus_tag="HTN63_RS00040"
                     /inference="COORDINATES: protein motif:HMM:NF022440.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_236918849.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLTAEFTIQVQQKKKYSST
                     RI"
                     /name="DUF2806 domain-containing protein"
     gene            complement(6077..6346)
                     /locus_tag="HTN63_RS00045"
     CDS             complement(6077..6346)
                     /locus_tag="HTN63_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            complement(6421..7068)
                     /locus_tag="HTN63_RS00050"
     CDS             complement(6421..7068)
                     /locus_tag="HTN63_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            complement(7731..7826)
                     /gene="dqlB"
                     /locus_tag="HTN63_RS00210"
     CDS             complement(7731..7826)
                     /gene="dqlB"
                     /locus_tag="HTN63_RS00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            complement(8609..9313)
                     /locus_tag="HTN63_RS00055"
     CDS             complement(8609..9313)
                     /locus_tag="HTN63_RS00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(9400..9864)
                     /locus_tag="HTN63_RS00060"
     CDS             complement(9400..9864)
                     /locus_tag="HTN63_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(9882..10088)
                     /gene="hha"
                     /locus_tag="HTN63_RS00065"
     CDS             complement(9882..10088)
                     /gene="hha"
                     /locus_tag="HTN63_RS00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            complement(10085..12238)
                     /locus_tag="HTN63_RS00070"
     CDS             complement(10085..12238)
                     /locus_tag="HTN63_RS00070"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            complement(12243..12815)
                     /locus_tag="HTN63_RS00075"
     CDS             complement(12243..12815)
                     /locus_tag="HTN63_RS00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001198960.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            complement(12819..>13013)
                     /locus_tag="HTN63_RS00080"
                     /pseudo=""
     CDS             complement(12819..>13013)
                     /locus_tag="HTN63_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            complement(13126..13431)
                     /locus_tag="HTN63_RS00085"
     CDS             complement(13126..13431)
                     /locus_tag="HTN63_RS00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_001350475.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(13415..13837)
                     /locus_tag="HTN63_RS00090"
     CDS             complement(13415..13837)
                     /locus_tag="HTN63_RS00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(13846..15708)
                     /gene="taxB"
                     /locus_tag="HTN63_RS00095"
     CDS             complement(13846..15708)
                     /gene="taxB"
                     /locus_tag="HTN63_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            complement(15695..16723)
                     /gene="virB11"
                     /locus_tag="HTN63_RS00100"
     CDS             complement(15695..16723)
                     /gene="virB11"
                     /locus_tag="HTN63_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017226.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            complement(16725..17843)
                     /gene="virB10"
                     /locus_tag="HTN63_RS00105"
     CDS             complement(16725..17843)
                     /gene="virB10"
                     /locus_tag="HTN63_RS00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            complement(17836..18744)
                     /gene="virB9"
                     /locus_tag="HTN63_RS00110"
     CDS             complement(17836..18744)
                     /gene="virB9"
                     /locus_tag="HTN63_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            complement(18741..19427)
                     /locus_tag="HTN63_RS00115"
     CDS             complement(18741..19427)
                     /locus_tag="HTN63_RS00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            complement(19766..19915)
                     /locus_tag="HTN63_RS00120"
     CDS             complement(19766..19915)
                     /locus_tag="HTN63_RS00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227648764.1"
                     /translation="MSLNWILVFVDKHITSGWSRKRKLITQLVILITGITLFKVLGGIS
                     QSWL"
                     /name="hypothetical protein"
     gene            complement(19942..21036)
                     /locus_tag="HTN63_RS00125"
     CDS             complement(19942..21036)
                     /locus_tag="HTN63_RS00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            complement(21048..21764)
                     /locus_tag="HTN63_RS00130"
     CDS             complement(21048..21764)
                     /locus_tag="HTN63_RS00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            complement(21776..24523)
                     /locus_tag="HTN63_RS00135"
     CDS             complement(21776..24523)
                     /locus_tag="HTN63_RS00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            complement(24542..24868)
                     /locus_tag="HTN63_RS00140"
     CDS             complement(24542..24868)
                     /locus_tag="HTN63_RS00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            complement(24882..25502)
                     /locus_tag="HTN63_RS00145"
     CDS             complement(24882..25502)
                     /locus_tag="HTN63_RS00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(25858..26073)
                     /locus_tag="HTN63_RS00150"
     CDS             complement(25858..26073)
                     /locus_tag="HTN63_RS00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            complement(26070..26363)
                     /locus_tag="HTN63_RS00155"
     CDS             complement(26070..26363)
                     /locus_tag="HTN63_RS00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_060598542.1"
                     /translation="MTEHDAICISGLHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            complement(26440..27669)
                     /gene="taxC"
                     /locus_tag="HTN63_RS00160"
     CDS             complement(26440..27669)
                     /gene="taxC"
                     /locus_tag="HTN63_RS00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            complement(27673..28176)
                     /gene="taxA"
                     /locus_tag="HTN63_RS00165"
     CDS             complement(27673..28176)
                     /gene="taxA"
                     /locus_tag="HTN63_RS00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            complement(28537..28884)
                     /locus_tag="HTN63_RS00170"
     CDS             complement(28537..28884)
                     /locus_tag="HTN63_RS00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(28881..29129)
                     /locus_tag="HTN63_RS00175"
     CDS             complement(28881..29129)
                     /locus_tag="HTN63_RS00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            complement(29434..29784)
                     /locus_tag="HTN63_RS00180"
     CDS             complement(29434..29784)
                     /locus_tag="HTN63_RS00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            complement(29875..30093)
                     /locus_tag="HTN63_RS00185"
     CDS             complement(29875..30093)
                     /locus_tag="HTN63_RS00185"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005058042.1"
                     /translation="MHKDTGQQYVVIFTDNNKIRDYKAGIVPQFGELKQSDVDLVLFYR
                     DEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            complement(30628..30855)
                     /locus_tag="HTN63_RS00190"
     CDS             complement(30628..30855)
                     /locus_tag="HTN63_RS00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            complement(30842..31093)
                     /locus_tag="HTN63_RS00195"
     CDS             complement(30842..31093)
                     /locus_tag="HTN63_RS00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            complement(31090..31632)
                     /locus_tag="HTN63_RS00200"
     CDS             complement(31090..31632)
                     /locus_tag="HTN63_RS00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            complement(31737..32252)
                     /locus_tag="HTN63_RS00205"
     CDS             complement(31737..32252)
                     /locus_tag="HTN63_RS00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     ARG             2525..4146
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          2..873
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(26444..27669)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(13850..15708)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(17840..18744)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(18745..19427)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          complement(19970..21036)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.69e-172"
ORIGIN
        1 atgagaatga cgacaaataa gacttccctt tctcgcttaa caaaagtgag acatcgaaat
       61 gaattgaatt caacgctgtc aacattgcct atggctgcta aaaaagtctt atttttagcc
      121 atgtgccaga taaactctaa aaatgaattc gatgatgatc acatatttta tgtgacagtt
      181 gccgattaca ttaaatgggt tcaggttaag cctgatgcgg cttatcttgc tttgagggat
      241 ggctctaata tattagatac gacgcttctt aagctgaaac atgatgaaat attagaactg
      301 agtagtgatt tgggatttaa gttcactaaa agtaatgtac ctgattcaat gaatttgagt
      361 ctgactgttt tttctactta ttacaggaat gaaggtagag tggggatcaa gtttacgaaa
      421 gaagcgaaaa gatttttatg taaacttatt ggtgaagaaa aacgttatac aacgcaagtt
      481 ttattatctg ttgttcgact gacaagtgtt aatgctgcat cactatatca actcattcgt
      541 aaaatatata gtaataattc tcgcgcgaat agttttgaaa tgacaataga tgaacttaaa
      601 gatgaattga atctttatac aataggggcg gggggggtga aggattataa gtatccagat
      661 tatcctgctt ttaaaagaga tgttcttaat aaatcagtaa aagaaatcat gaaacatacg
      721 gaagtaaaga acttaagttt cgtagtttca gaaaaaattg ggagaaaagt ttataaatta
      781 aagttctctt atacaattgg ttatgagggc gataccaggg aagactcaga gtttactaat
      841 atgtttgata aaatgtaccc acctgaaaat tgaggtcata acaatatgaa ggataatatc
      901 gtagattttc aaagaatcag ggacagcatg aatgatcatt caaccgatgt tgcaaatgat
      961 gccgtttatt ctgacaaaaa gaaaatatcc aggttctttt atctgctgac acctgtcaga
     1021 taccttctgg ctgcttccct ttatctggtt gttgttattc cattggggat tcttgcggga
     1081 tttcgtttct tgttgcagtt tttaggcggt atcgcagtga tgggtttaac tatcgcctgg
     1141 tacatgggtg cagatgtcag tagttacgtt gttcttgctg catggatcgc cttaactgtt
     1201 tgtggttgcg cagagcagat ttttgaatgg tggatcgaaa gccgttttgc gttccgtctt
     1261 tttggtatcg ggagaacgcc ggaagaatga gcgccgatct tacagacagt aaagaacaat
     1321 gcaggataga caatccgatg tcaaatgtta acatttgaat cagattgtcc aaaaacgatg
     1381 tttttgcctg tgcctgccgc aggctctttt aaaaggaata tgaaatgata tttaaccgta
     1441 ataaaaaacg agatgaacaa cataattctg ctgttgtttt gccatcagct gaaaatgtat
     1501 tctctgattt tattaagaac aatccagctt tgacaaccaa tgcttttaca gccattgggg
     1561 aggttgattg ttttactaaa gtacccttac tctcaaataa tgaatcagag tttttaggca
     1621 ttctttcacg taatattata cctgattatt ccgtttttcc caaaatacgg ctcattgaat
     1681 ttgttcgtcc tcatggtagc gaggaagctg taaaagattt aatccgtgaa gtgcagaata
     1741 taacctgtga ttttgtcctg aaatcatatg atgaaacagt cctggctgtt atccagtttg
     1801 gtgaaaccgc aaccgtcaga cagcaaaaga aaaaactgat tatccagcgc gtgtgtgcta
     1861 tgacaggaat ttcttttttc gaatttaaaa acactgtcga tatgatgggg agcgaagatt
     1921 tttgtcagtt cctgcgggat gatgaagagt aattaaaaat aagcccacat atttgcgggc
     1981 ttaacaggct ctttattagt acttgctgca tttgtgatta ctggcaacac agttttcact
     2041 gggcagtttt tgcggtcgct tttaattatg gttagtggaa ctcagacagg taactcgacc
     2101 tctttacata ttaataattg atagttttac ctggcttcct tcaacattta ttttgttgag
     2161 gaatttattt aaatacgcaa tatctggagt ggaaccgcat attttcatca attcttgacc
     2221 gataggcgta agtaaagccg ttcctattgg tagtttccag gttgatgaat catcgctttg
     2281 aaactcaact gaaaaaaccg ttccgtaata accgatacga ccgtttttac ttttaagata
     2341 caaattataa atactctcaa gtgtatattc agtatgggat tgcgcaatga ttgcctaata
     2401 aaatttctga aatatttctg tatcgcataa ttttttatat cagataaatt gtactggatt
     2461 tcttaaaaaa ttgcagtata attgccgcaa ttatcccacc gtttattttt tgagtagttt
     2521 ctcatgatgc agcatacttc tgtgtggtac cgacgctcgg tcagtccgtt tgttcttgtg
     2581 gcgagtgttg ccgttttctt gaccgcgacc gccaatctta ccttttttga taaaatcagc
     2641 caaacctatc ccatcgcgga caatctcggc tttgtgctga cgatcgctgt cgtgctcttt
     2701 ggcgcgatgc tactgatcac cacgctgtta tcatcgtatc gctatgtgct aaagcctgtg
     2761 ttgattttgc tattaatcat gggcgcggtg accagttatt ttactgacac ttatggcacg
     2821 gtctatgata cgaccatgct ccaaaatgcc ctacagaccg accaagccga gaccaaggat
     2881 ctattaaacg cagcgtttat catgcgtatc attggtttgg gtgtgctacc aagtttgctt
     2941 gtggcttttg ttaaggtgga ttatccgact tggggcaagg gtttgatgcg ccgattgggc
     3001 ttgatcgtgg caagtcttgc gctgatttta ctgcctgtgg tggcgttcag cagtcattat
     3061 gccagtttct ttcgcgtgca taagccgctg cgtagctatg tcaatccgat catgccaatc
     3121 tactcggtgg gtaagcttgc cagtattgag tataaaaaag ccagtgcgcc aaaagatacc
     3181 atttatcacg ccaaagacgc ggtacaagca accaagcctg atatgcgtaa gccacgccta
     3241 gtggtgttcg tcgtcggtga gacggcacgc gccgatcatg tcagcttcaa tggctatgag
     3301 cgcgatactt tcccacagct tgccaagatc gatggcgtga ccaattttag caatgtcaca
     3361 tcgtgcggca catcgacggc gtattctgtg ccgtgtatgt tcagctatct gggcgcggat
     3421 gagtatgatg tcgataccgc caaataccaa gaaaatgtgc tggatacgct ggatcgcttg
     3481 ggcgtaagta tcttgtggcg tgataataat tcggactcaa aaggcgtgat ggataagctg
     3541 ccaaaagcgc aatttgccga ttataaatcc gcgaccaaca acgccatctg caacaccaat
     3601 ccttataacg aatgccgcga tgtcggtatg ctcgttggct tagatgactt tgtcgctgcc
     3661 aataacggca aagatatgct gatcatgctg caccaaatgg gcaatcacgg gcctgcgtat
     3721 tttaagcgat atgatgaaaa gtttgccaaa ttcacgccag tgtgtgaagg taatgagctt
     3781 gccaagtgcg aacatcagtc cttgatcaat gcttatgaca atgccttgct tgccaccgat
     3841 gatttcatcg ctcaaagtat ccagtggctg cagacgcaca gcaatgccta tgatgtctca
     3901 atgctgtatg tcagcgatca tggcgaaagt ctgggtgaga acggtgtcta tctacatggt
     3961 atgccaaatg cctttgcacc aaaagaacag cgcagtgtgc ctgcattttt ctggacggat
     4021 aagcaaactg gcatcacgcc aatggcaacc gataccgtcc tgacccatga cgcgatcacg
     4081 ccgacattat taaagctgtt tgatgtcacc gcggacaaag tcaaagaccg caccgcattc
     4141 atccgctgat ttctccctgt attttttcca aacccaccgc acactccatt cgtattatgg
     4201 gcggtggggt ggggtttgtt atgccgtatt tatcaaataa acgcctactt gctgagatga
     4261 gtatcgctct tgtcatggcg atcgttgcca cgctgaccct tgagcacagt cagattgatc
     4321 tgatggtcgc tgattggttt tatctgggta tggggcattg gatggttgcc aagcaagctt
     4381 ttttgccaga tttgctactg tattctggac taaaaaagct gctgatggcg atgctgatct
     4441 acttgctggt tgcgaccatt tgccgtgctt atcatgagaa aaagggcaat gctatcactg
     4501 ccaagtggct tgtcccagtg acaaaatttc gcgtgcgtga gcttgcgtat ctggtgctga
     4561 ctttgatcct agtgccgaca gttgtcgcgt cattgaaggc atatactcat gtggtctgcc
     4621 ctgtgcattt gacgattttt gatggtacgc tgccgtattt gccgatgctt gatagtatgc
     4681 gtaacaccat tcctgataag tgctttcctg cggcgcatgc cagtagcgga tttgcgctgt
     4741 ttgcctttgc gtttgcgcca agtttgcgcc gccgtcgtgg tgcgatcatc atcgtggtga
     4801 tggcattggg ctgggcgatg ggctgctata agatgattat tggcgatcat tttttgagcc
     4861 atacggtggt gtcgatgatg cttgcgtggg cgatgtcggc agggcttgcg tgggtgtttt
     4921 ttaagaaggg tgaacaattc aaggtcagaa acttttcttg caccaaattg aaatattcag
     4981 gctgctctaa tttgcgctgt gctttgctat tttgacgatg cttcaaatag ctgttttgtg
     5041 cgttcgttgc actgtagctt tctagagcgt gtcgtttcag ctcgcgagaa atggtgctgg
     5101 agctacgtcc cagtgctttg gcaatttctg cttgtttttt gccctgtgcg agtaaaatca
     5161 ttatcttttc tcgctcgttt attgtaagat gtcggtagga agtactcatc atttggaagt
     5221 ggtttttgtg tggaaacaaa attatattct agttgatgag tacttctttt tttgttgcac
     5281 ttggattgta aattcagcgg ttaaactata accaatgcct tgttgaataa cgcctaagga
     5341 gtctaaaacc gaaagtttat cgaaagttat accttcagta tctccattct catcggtaaa
     5401 taaaattgga gtgagtttgt ttgcctgcca aacaaacttt ccaaaataag taataaggtt
     5461 cgcttcttct ttgcttatag tggataatag ttttaaggtt ctacgactaa acgaaccttt
     5521 tgactttgct tcttcggata aaattcttcc ccaaagcatt tgcatttgtt cgtcactaat
     5581 atcctcacac tccctgaaga aagcctctat ccaatcttcg tcaatatcag aaacattatc
     5641 actctcagat agactttgtg ctgcttgcat tgttatattt tcaatgtttt cctgtcgttt
     5701 cgtttcacgt ttgagaaaac gctcaactgc ccgtttttct attccctcaa gctctaacct
     5761 agaaattagc tctgtgcgtt tagcttcagc ttcagccttc gcttttttcc tgattcttgt
     5821 aggttcataa agcacaccaa tagcatcact tattttttca ataagttttg ttcctggttc
     5881 tgataatcct gataaactta aatcgataag gctcatctag tgctcctaaa tacccgtgca
     5941 acaactgtac aagggtattt tattgcaaga gtaactaaaa atgaatcaca actacattta
     6001 aaagtgatga agttagtaca ttcagataag tatctaaaag aaaatgataa agagtttatt
     6061 gggccacttg ctatgattaa tcatttctgt cagctctgaa ccacaaatta atgagttcgt
     6121 tttcgtccag atcctgataa gccagtaatg ctgctttgat tatttttgtc ttgggacgat
     6181 gcagtctttt tgattcgtta tcaatgaatt caagcaattc attcggtatg cggaatgaag
     6241 ccagttttgt tttgttctct gtggggcgtt ttcctgcgtc ctgaacaaat tttgtggcgt
     6301 tcacttcctg gttttgttct agttctggta gttccagctt tgccatgatg taccttctaa
     6361 tctgattgtt tcacactaat gtatatcatg atgatgtaca ttagtgtatg tcactatgat
     6421 ttacagttcc agttctttca gcaagagttc gatttgtgct tttgcctggc tggcaccgct
     6481 aacattactt tttaactcgt gaacccccat tccctgattc attgctctta caaaggcccg
     6541 gagaaaagaa accgtgcttt tcattggttt aagccagtaa tcatggctgt tgagagagtc
     6601 tcttaattct tgttgttcac tgaacgtatt tggctggcat ttatacagga gcacatgtgc
     6661 agccagcctg ggatttattt tttgcgcatc cctgacaatt tttgtcacag tctgaagact
     6721 gtctgcttcc acctgggcaa gcgggtcgat cgggacaatc acaatgtctg caacttttag
     6781 tgcagttctg aactccgtgc tgtcatatcc ggcagtatct ataatgagga tttctgctac
     6841 atctgccatt tttgttattt tggcactgat gtcgccatag gcttcattta atgcgacggg
     6901 cggtaatccg gcctgttctc tgcgtttatt ccattttttg gtcgagccat tcaggtctgt
     6961 ttcaacaagc cccgttctct ttccctgttg tgagaggcaa acagttaagt tggttgccag
     7021 atgtgattta cctgtaccgc ctttatcacc accgattacg ataatcatag taccccttgt
     7081 atgtcacagt gatttactca tgtgtatttc tatgtgatgt acgcatgcgt atgtcacatg
     7141 gacatactat agtgtatgtc acaatgaatt acaatgatgt acatcatgaa gaaatacatt
     7201 attgtatgtc agtgtgatgt acccgttggt tggtcacttg aaagcaaaag tgacagcgtt
     7261 actttcggta tcctcccttg ctgcgaaacc ttgtggcaat acagcaatga gtatgtttag
     7321 ttacaacatt caaaattaag cgattagatt ccgcccgtac gggcggggcg cgccactttc
     7381 tgtagtgggg aggggcaggg aggttatgtt tgctggatga gcggaggatg gaatgagcta
     7441 ttagaatgtt gtaactaaag ggtatcccaa ttaaaggcca cttacgcggc ctttgtctgt
     7501 cggttcttcg gtctggtgac ataccacgat aaacatccca cagcaacact cataagcatt
     7561 ccggataagc gatcatcgat gccaggaaac aggcaaccga caaacatcgc aacagggaaa
     7621 ggaagaagta aacagcgccc caaaatgctc ataaaatcca taaatcctcc ttttttgtta
     7681 aagggcagga agcggttcac ttcctgccct tagttacgtt tccgttgtca tcaatcgatg
     7741 aattggcgga tcagttccag aactgcaatc agcgcgtttg caacggcgac cacagctctg
     7801 agaacgatga ttaacatatt aatcatccgt ttctccagta aaactggagg aaatcaccgt
     7861 tgcttgctca tacactgcct gtcacaacgg ctctctcgca ttgttaggtg tagagtgacc
     7921 tcctcctgcc agagcaccga atacagcacc acctgtttat ccagccagga ctttaaaatc
     7981 gttcataccc gcagatacgg gaacagcagg attgcaagcc aactacatga ctaactgact
     8041 gattatacgc tacacaaaac acccgttaca ccactaaatg tggttcctta accacattta
     8101 gttgctttac agcaccatag tgaataaaat gtaaacgtta ggtgtagagt aaccttctcc
     8161 ggtcagagcc accaactcaa gactggaaaa cgcaaaaaag cccgattacc agtcgggttt
     8221 ttttgtgcct gtcgttcggc tgtagttccg ttttttctcc ttcatttgag ggatttttct
     8281 ttcatttttt ttgttgcttc caatactgcc tgtcgcgttg gccaacagct tgacgcgtta
     8341 ccggcatttt cattactcaa tatttttcag tgaattaaaa tgcaacagcg acagaaaagg
     8401 acattcagct ttttagatga atgctatagc aacggtgtgc tacgtaaaat ctgcgaaaaa
     8461 agcaggggta gggtaggtta tttttcacgt agcaacgcca tctggcactg tacataggta
     8521 tgtcacacag acatacctat gtgtatgtct gtgtgaggca ctgttgcaaa gttagcgatg
     8581 aggcagcctt ttgtcttatt caaaggcctt acatttcaaa aactctgctt accaggcgca
     8641 tttcgcccag gggatcacca taataaaatg ctgaggcctg gcctttgcgt agtgcacgca
     8701 tcacctcaat acctttgatg gtggcgtaag ccgtcttcat ggatttaaat cccagcgtgg
     8761 cgccgattat ccgtttcagt ttgccatgat cgcattcaat cacgttgttc cggtacttaa
     8821 tctgtcggtg ttcaacgtca gacgggcacc ggccttcgcg tttgagcaga gcaagcgcgc
     8881 gaccataggc gggcgcttta tccgtgttga tgaatcgcgg gatctgccac ttcttcacgt
     8941 tgttgaggat tttacccaga aaccggtatg cagctttgct gttacgacgg gaggagagat
     9001 aaaaatcgac agtgcggccc cggctgtcga cggcccggta cagatacgcc cagcggccat
     9061 tgaccttcac gtaggtttca tccatgtgcc acgggcaaag atcggaaggg ttacgccagt
     9121 accagcgcag ccgtttttcc atttcaggcg cataacgctg aacccagcgg taaatcgtgg
     9181 agtgatcgac attcactccg cgttcagcca gcatctcctg cagctcacgg taactgatgc
     9241 cgtatttgca gtaccagcgt acggcccaca gaatgatgtc acgctgaaaa tgccggcctt
     9301 tgaatgggtt catgtgcagc tccatcagca aaaggggatg ataagtttat caccaccgac
     9361 tatttgcaac agtgccctgt gtgatgtata cttggcgggt tattctgcct gttccggctt
     9421 agttttctca atgaggaaat cttccatgaa atgcccctca tcaagcagct tctgtaaagc
     9481 aagcggacgc ttgccattac cagaccattc tctgatctcg ccattttcat ccttaaagcg
     9541 gtatttagcc tttcttactc cgcctttggc tttccgcctg gtttttactg tatctgctgt
     9601 tacaggagca aggagtgatt cgggatcaag acctaaagat atgatgtatt caatggcctg
     9661 ctgacgtttg gcttcaagtt cctggcgttc agccgcttca cgttcagcat cttcacgacg
     9721 ttcttcaata acaacgttga gcttttcctg catttcgagc aactgctcaa aatcaatctc
     9781 acgggcaaaa acacgcaatg aacgaatatt catcatagta cggctgataa tgccgtattc
     9841 atcttcttta gtcagttcgc tcatataatt aatcctctta tttagtgtac gtacttccag
     9901 acgccggaag gcaccttatc ataaagttta ttcatcacca gttctgctcg gcgatgatct
     9961 gcggcagaat aaaatgcctc tgattctgat aaaggcagtt tgtaacggtt aatctcaata
    10021 actttttcaa gagtatctct tgatgtacat tttcttaact gaaaaagcca ttcctgcttt
    10081 gttttcactt cttagccctt gccggaaaac ccagcttccc tgttttctta tcctcaagga
    10141 caagaactgt atcatacgtt ccaccacttt tctttttaaa tcccttaatc aaatcggttt
    10201 tccctgattt aaccagtttt tcggcctgtg cctgggtgat tttcttacca gaaaactcac
    10261 tccagatttt aaattcacat ccggtacaga aataaccttt cggcctgata acaatatgtt
    10321 taccacagga agggcaggga gagtccaggc gttgaaactg ccctgctggc gcagcgggtt
    10381 caatcttcat ctcgcccagg tcaacatcag aaatcatgcc tgtcagttca ccgtacagat
    10441 cattaataaa ctgttcaacc gtcaggtcgc cattttctat ggcagcctgc ttttcagacc
    10501 ataatgctgt catatcagga ttaaccgcta taccaggcag ggcatcaata agcgcatatc
    10561 cggtatcagt aggaataagt ttcccttttt ccagcgtgat atagtttctt ttcttcagcg
    10621 tttccagaat ggctgcgcgg gtagctggcg taccaatgcc accatgttca tcttttttgt
    10681 ctttatcctt atccttcaac aattttttaa ttgttggatc agtgacaaaa tccgcgacac
    10741 gaacaagcgc agcaagcaag gaggcttcgg tgaataacgg cggcggtgtt gttttcttct
    10801 cattaacaat aacttctttt gtcgtcagtg tttctcctgt gcgaatttta cagagcagtt
    10861 caaaagcgga atcatcatta tcttctgatt caccttcgtc tgtggtttcc gcgccaagaa
    10921 acgcctcaaa tccgctgtca gttgtttttc tggcacgggc atagaacgac tcatcaccac
    10981 actgaatggc aaccgatact tcctggtatg ctttttcagg catgaactga acaagatagt
    11041 gttgtgcgat cgccaggtaa acattgcgct cgtcggtgct gagtgcgtta acatcaggca
    11101 cactggcggt cgggattatc gcagtatgcg cagtcacctt tgcactgtta aacgctttgc
    11161 ttttacgtgc agaatcaata tccagcgact gaggaaagac tgatttcagg gcatcgataa
    11221 cctgcggcgc ttcgctgaat tgttcatctg aaagatatga gcagtcagag cggttatacg
    11281 taattgcttt atatttttcg cgtagttgtt gcgtaatatc cagcgttttt tgtgccgtca
    11341 ttttaaactt cttgttcatg tattgctgga gtctgaccag attaaacggc aacggcgcag
    11401 ccgttttttt atcatcagtt gctgctgctt caactgtagc cggttttcct gcaagggatg
    11461 cagccgttcc gtctgcccac gctttatcaa gtaatttacg gtctgtcagc ggagcaaatt
    11521 cccctggctt ccagttcgcc ctgataacat cagcaccacg ctgaaagact ccggtcatgg
    11581 tgtagtaaaa actggattta tggttctggt tagcacgggt acgattcaca atcaggccaa
    11641 gaacgggagt ctggacgcgc ccgacagaca gaacgccctg atatcctctg gcttttgccg
    11701 gaatggtgta cgcacgtgtc atagagaagc catagacggc atcggcaact gaccgcgcca
    11761 acgccttaag gtaaagtcct ttgaaatcac gattgtcttt aagatttgcc agtgcctttt
    11821 tcactgccgg aagcgtgttg tcgttaatca gaacgcgctt tacgggtttt gtgttgcctg
    11881 catattccag gacttcatca accagtagct gtccctcatc atcaggatcg ccagcgtgaa
    11941 caatttcagt cacgtctcca cgtctgataa gttcgagaat cgttttaacc tgttttgctg
    12001 cactttcaac aggctgatac ttcacgggat aaagacgtaa aggaagcgtt tcaaccttcc
    12061 aggctttgta ttcaggatta tagttttccg gcggttgtga ttcgataata tgaccaaaac
    12121 agttagtcac aatggcgtta tcactttcaa accagccatc atggcgggta aaattgccac
    12181 caagtgcctt aacaatatca tttgctactg cgggtttttc tgcgataaaa agtctcattt
    12241 tgttatcctt tacattgaat taatcttttg gcacaacgga tagcgcgttc ttccgatact
    12301 gtatgttgcc agttatcttt acttactact ctgaatctgc gctcacagcc attaaaggca
    12361 aaaattccct cacggttaag tatattagtt gcaatatccc actctttaat tctcaaaaag
    12421 gctgttacag caaaaccaga atacgaagca atttttgaaa tgatgcattc atcagctttt
    12481 attaacgcgg caaaaggaac tatcttttga tgaccacacg aaatcagagg gagtgtgtga
    12541 atatcataat aagctattga atgacaatcc atgcgggtat catcaatagc tgccagccag
    12601 aatcctgcct ggtcttttat ttttctgcta atatctgaat ctgaaacacc agggtttaat
    12661 aaatatccac cataacagat atggaagggg tgagcagatt catcaatatc aggaagttct
    12721 tttaccggat tttctttcca gtccttcaga acaccgaatt caagagcatc cagcaaaaac
    12781 tttcgttcaa atccatcaaa caatgcatat tgcatgtgtt aatcctccag gtaacttaaa
    12841 tagtcaggtt gtgccccgtt ctttttataa agttcttccc tttcctctat atcttcatct
    12901 gcttcctgaa cgctcagatc gagggttcct ttcaaaaagg cacgagcatt ttttattaca
    12961 tccacttatg cactaccagc agataagcac aataaaatag ctataataga tttggttact
    13021 ttcatttcta acctcagtga ttgtaactaa tcatcacatt tcgttggcgc gaaatgtgat
    13081 acttgcagta ccctgatacc cgttggcgcg gttatcaggt tttaattaac ctctgacacg
    13141 accaaactta ctcatgattt ttgatatagc agcaggatca gccgttgaac actgattcag
    13201 aaatgcttta cgggcatcaa aagttttact ccagcgaatg cttccttttt tctttttcag
    13261 aatattaaaa aaatcctttt cagcacttct gcattcactc cctccacctt gcccgactgc
    13321 ttttccatat aagcaaagta ccgaagcgca agggtcagat gcattagcat ttgttgatat
    13381 taatcctaac gccagcaagg ctggtaaaac cactctattt tttccagtca tttttcacct
    13441 cattttgtgc tttaatgaaa actattttta cctgttcagg taaaaaactt ttctcgtttc
    13501 gccattccac gactgctgtt gccccttcca tcttcaacag atctctgatt cgaaaccaca
    13561 gcccagcatc atgtgttgtc actacaatcc tgtccgcatg agccagagcg taataaaacg
    13621 tcggcgttct ggcctgtact ccggataagg aagtgatctc ataaacccat cctttaccgc
    13681 taacgtctga ctttatgaca ccgtgaaaat cggggacata tggcaatgag ggattgatca
    13741 cttcatttgc cttttcaaac tgcacgggtg ttggctctgg cggtgatgaa caaccagcaa
    13801 gaatggaaat caataaaaac actaacttct tcatcatgtt ctcctttatg ccgctttatc
    13861 gagatcagga acatctttta ctaccagata cccttttgcg acgatttcat tttcaaatac
    13921 tttctgtgga ggcataacca gctttccttt cttcctgggg aaaatgtttg caagttccgg
    13981 agcaaccttc acaaagtcac caaagaaata ctcattgaga tagtagaatg ccttttcaca
    14041 acgaatcggg ttttctccct tcattgccag gatttcttca ctaaatttca gtgtaagtag
    14101 ttcatttgtt gttaccagtg gacgctcaat aaggctttct gattcagatc tcgatgttcc
    14161 tccacgacta cgacttttgc ttttcgaacc gatagttact gttcgtgtcc ccatcgcttc
    14221 tgataactcc cgcgcatctt taacatcaga agcggaataa acaattttgc agggtgcact
    14281 tgccagtaat gttttactgc ctgcataact gtagatttcc tcaagctgag agccgacctg
    14341 gtaaacaatc aacaatttca gcttgtaacc agcaatgaga ccagatttac tcttgatgta
    14401 atctacagca ccaattgacg ggaattcatc cagtagaaaa aggcagtcat gctttatttc
    14461 cggatcatcc gttggcatct tttcaagatt cacctgtata gcaagctgaa agaaaatatt
    14521 tgttattttt tcagccaacc tggcattatc accagaaata cagaaataaa ttgtcatccg
    14581 ctttttccgc acctgccgca aatcaaaatc atttccatca gtagcatttg ccacattggg
    14641 gttagcaaac ggtgataatc cattaagaaa gttgcttttg agttgtgctt ttgttttatc
    14701 ctccatctca atgaatgcct taaggccagc gacaccaata tcagcaagcg ttttgtcttt
    14761 cccccttaat tctgaacgaa tatcattcat gaatgaaaga agatgttcgg gttctgcacg
    14821 ctcaaaaagc tgattaattt tagacattga gaagacaggc tcaatatcaa gcgtttttag
    14881 tccagcctta tcattcttaa tcataaacca taaagcgaca gcataagatt taaaaacacc
    14941 acccgccgtc ttattaagat agctaccagc atccgcacca tctgtcttat aggggtaaat
    15001 aatcaacgaa agattttcaa gctgattaaa accttcactc gttcccatgc tgacataata
    15061 caaagggtta aagcggtgcg ttaccgaact aaagggatca aatttataaa cctcatgacc
    15121 taaaatcacc ttcctgataa gactggtgat attaaaacac tccctttttg gatcgagaat
    15181 aataacactc caccagtact tcataagatt agtgatgact ataccagcac ctttaccagc
    15241 ccttgttccg gctcccatag cactgaatgc tgctcccaca tagcgtatga ttttcttgtc
    15301 ttttatacca acgataatcc cgtctttttc gtcaccgtca agcgtgaaac tgttagactc
    15361 acgaatatca ttaattgttg caaatcgcgc atcaccgaaa atattttctt tcttctcgtt
    15421 cagttttatc aacgccgcaa cagggatgat aagagacacg acaaatcctg ctccaagtgc
    15481 aacaaaggct aaaactctga tatccgtagt cacaacagat aaagtaaggc tgtctgtaaa
    15541 aatatccatc ctgtacgcat caatggatct gaacacagcc ttcaatggtt tcagattctt
    15601 tatctggctg aagtaaagca caaagaaaat aaatgaacct gcaaaccatg ccgcaacaag
    15661 cataacagcg aatataaaaa cagattgcga cttattaaaa gttttcacat tcagcccctt
    15721 tgtaatagat gtcgctcata tgcctgacaa caccatccct gcctacatga acaacaatat
    15781 caatactgtc cataatgatt ttacgaagaa catcaaaagg aagattctga cattctctgt
    15841 tctgataaca ttttgtcacc atctgaatga tggcatcttt tgccgaggcc gcgtgaatgg
    15901 acgtcatgct tccactgtga ccagaaccag caactttcac aaaatcccag gcatcgccac
    15961 ctttaatttc cgccagtaaa attctgtcag gtttcatcct caaacaggat ttgattaatt
    16021 tcgctgctgt tatgatagag ccggaatcac tgccggattc cgaagggtaa aaaagatgca
    16081 cataattttt atggataaaa aatttgattt cctctgcatc ttcaatcgta atcagccgtg
    16141 tattcaatgg tatgaaatcg ataagactct tcatataagt tgttttaccg gaacccgttg
    16201 ctccggcaaa tacaatggtt ttccctgctg ctacggcaag ctccataaaa gcagcgatat
    16261 ttctcgctct gaataaatca agaagctcat catcgtatgt cctgtgtttt tttcctgact
    16321 ggacataatc ataaaaaccg ttcgccacat attctttatg tgttatctgc cgtgtcgatg
    16381 gtttacgtat agtgattgaa atagtatttc tctcacatgc aggaggaaaa acgacctgta
    16441 cacgttctcc tgattccagt gttgctgaaa gtaatggctt ggtctcgccg atttcatctc
    16501 cccgaaatga tgccagcgta tgagaaaaac gtttacaaaa atcaaaggtc acactgtcat
    16561 tattatggaa tgtccagtca ccattaattt ccgtccagat ttcaccagga cggttgacag
    16621 caatttctgt tagcccttca atatcaagaa aagactggaa tacttgattt ttataaaaat
    16681 cgagcgattt attgctaatg ctgacaggaa taacgccact catactattt tacctttaac
    16741 tcatagatat cagaaaaatc aatgtcttcc ccgaccataa tagtgattat gtcaccctgg
    16801 tttttataca ttgttggagg aatatttatc gaattctcaa gtgcgacttt agccatttca
    16861 gccattgcct gtcgtgagtt ttcggtataa tccacattac gatctttacc aggtgcatta
    16921 tccgccgccg ccgccgctac atcctgaacc atactgagca taagagaacc accaaaacgc
    16981 tcccagaagt gagaatcgat ccatccatca atgcccgctt ctcccagggg accagctgct
    17041 gctgtattta ccatatcgat tcgtttatta tcaggcgtcc gcaactgctc ccacataacg
    17101 aacattctgc cctgtccatg attcagcgtt ccggtctggt aacgaccaaa agccttagtt
    17161 ccctgttcca gtaattttgt gtggtgatta gcactccata catcttctgt aaaaacacaa
    17221 ctgatacgac ctgcaacatc agaaacaaag cgtgtggtta aagcacacgg tataagcctg
    17281 ttttcctcaa tatagagatc aggatcgaga ttaatcgcag ttactttcat tcctgattta
    17341 ccaggcacat tttcttttga ttctttcctt tcttcctgtg gctctgatgt ctgcgatgtc
    17401 ctgctgctgc cactcgcgcc agtctgactc cctccctgac cagcaacagg tattgacaaa
    17461 tatttcctga acccctcctg tggcacttct ttatgaccgt cagaaacagt attaccagaa
    17521 ccagtagcgc ctggattgat aattgctttg ttctcaacag ggtcaaaatt ctgaccaaga
    17581 ccagtacgga ttttacttac ctgagaaatg ctggtatcgc ctgttgattc tgatgctttc
    17641 tgctggtcat ctgcaaaata atttttatat gttttcagcg caaaaatacc aataactaat
    17701 acagccatca gaccaaacag aaagccagaa cgcatacgat tatttttgtt cctgatatca
    17761 ccgatatcat gaacgggttt actttccagc tttgactgat tcgcatcatc aactaaatca
    17821 tctgtttttt tcatatcagt cattattcac ctcaacacgt tctaccgcag gagaagatgt
    17881 attcctctgg tcggttaata cttttccgaa agatttattc acaacaccaa caacgctgtt
    17941 tccatagcgt aaaacaaatt tgtcattaac gttgtggata accataattt tatacttgcc
    18001 ttttgtttcc acattaaaag caagtgtctg ttcctgacca tctcttacag caaatggagc
    18061 tgggaatact ttccctgagt taaaacctaa aaaggtaaat atgccattat cataagcaaa
    18121 atcaggggcg atacgacgac tgtcatattt ttcattgact cgcatgaaat aattccagtt
    18181 tttaggcgca tcggcttttt caaaactttc agaaatcagt ttcttctgtc tgagtttttc
    18241 ctgtttttct tttgccagcc ttacttcttc tgcattcttt ttcgctattt ctgatggata
    18301 gcggaattgt acaacataag caggttgcgc ttgtttttct tctgacagaa ggattagatc
    18361 cagactgtaa atccgctttg ttgttctgac aaaaagattc gtatcccatt ccttttctgt
    18421 tggctggaaa acctttttca gtttttcgcc ttcatcgcct tcctgttcct gaacaacggg
    18481 acgcggattg atgtaaacaa cattatcatc ggttgtgatt tcccatccgg caggaaaacc
    18541 agcctttgca ctgataacag cctcaccttc atcaaaaaca actgatgtga gaaatcctgt
    18601 ctttgaccgg ataacggtcg tattcgcacc gttataactc acagtctgca tccttgcatc
    18661 aaatccagaa ggtaacggag tcgctgctga atacacaagc ccaggaagca ataaacatgt
    18721 agcaataaat aatttcttca tcattccccc ctgacttccc gatctgtctg gtaactggtt
    18781 acagtaaaac cgagaggatt aagctcacga ctggaacttt taaccgactt ttctggttca
    18841 aaacgatatg tcacacgagc cgtccagtat gaaactgaaa cctgtccggt cgtgaagttt
    18901 ctcgtcgttt ttttaaagcg cacagaggcc agtttatctg gcgcggttgc gtcagaaata
    18961 atattggaga tgacctcaac cgcaacgtaa gaaccgttat tatgataaat tttatcagga
    19021 gccatatcgc tgttatacag acgaagataa tcgtccttta ctgtattcga gctatatagc
    19081 tgtacagtct cataatcata ctgaagagac ggataattat aaccttcacg taaagtaata
    19141 tacgtgttta caaaataccg cccaagtgct tcagattgca ggatcttttc ctgtttaacc
    19201 tgagtaatca gttctgtacg gcctgttttt tcgccaacag ccacaatagc aagctctttt
    19261 tcttttaatg gcacaagaac acaaattgca gccccaagac ataaggacag taatgatgct
    19321 gccactgcaa cacgccatgc atttttctta gaccgttcat tttctgcata gagttgtctt
    19381 tcgaaggatt tagctgtctc aatcttcttt tcgatttttt cactcataac tgattacctg
    19441 gctgtggtta atgggttcca gttcgccgga aacatcagaa ggaaggttat tccttgtggt
    19501 acatccggaa atctgaaaca ggaaaaacaa aagaatcaca catcgcataa attcacctta
    19561 ttaagcgttc acgaacacct ttaagagata aaggccaaga tgaagaaaaa gaatcccacc
    19621 aataagaagc aaaaagcgaa gatccatacc ctttctccat ttccccgcaa gccctaaacc
    19681 aagtcttatt cctgcgaagc aggtaaacac tcctaaaaga aggattagga caaaataaag
    19741 tatcatgaca aaataatgaa gcatgtcaca accagctctg actgattcca cctaagacct
    19801 taaataaggt aattcccgtg attaaaataa caagctgggt tattagcttt ctcttcctgc
    19861 tccatccgga ggtgatatgt ttatcaacga acaccagtat ccagttcagg gacatcacat
    19921 aaaaaaaacg tttcattatt ttcatgcggc gttcctcgct cgtgcttttt ccagggatgc
    19981 aagtcttctc gccttcatcc ccaaagcacc tgtcggagcc agcgcctgat atcccttttc
    20041 acccgcccat tcagcggctg ttcgcgcacc acgccccatc agattccctg ctttccctga
    20101 taaagaattc atgcccgttc ttccggccat ccctaagcca aaacctaaac cagcacgacc
    20161 gccaagcatc agagacttac cagtagccat accagcagca cccagcccca tcatggctgc
    20221 gccctgaaca gcaccttcaa cacctgcacc tgctaactgg acagcaaaac ctttagctat
    20281 aagaaccaat aaagccccca aaaacccagc cataaagccc atagcacctg tagatacaag
    20341 atttacattc cctgtttgtg cagcacgaat agcatgggaa aggatcatcc cttgaaaatc
    20401 cattgctatc cgaatcacta aactggcaaa tagaactgtc agaatactgg agaataacga
    20461 ttgtaaccaa ttattaaaca tgctccgaat aaaaccaaac atgagacaaa agataaatat
    20521 cggtgctgta ataatcagga gtttcatcgt tacatctgct gttaaaaaaa caaccacact
    20581 aacagccatt aaaataagcg agccagtcca tattaaaaac tgaccaacta caccttgatc
    20641 tttaacatat gttgatttat ctaaagagta tatttccgca ccaagatttt gcgtactttt
    20701 ccataagtta tctaaagttt gccagacact cacccctcca gaaaaaccat ctttcatgcc
    20761 ttgcaacgca tcagtagccg cagttaaata cccatccgca ttagttataa acatgattat
    20821 gattgcaaat tttgatagat cccatactaa atcctgcaag ggcgtctgag ttttactggc
    20881 aagtatttga tatcctttcc atagtacata taacgtaacc gataccgttg ctaacgacat
    20941 aatatcatta gcaaattgtg tttgataact ggagctgatt ttatctaccg aatccataac
    21001 ggtagaatta tatttaacga aaaacccctg agccatatat ccacctttta atcaaaagtt
    21061 aatggttcag cttctttctg ctgtttaata aaggcctctt gttcttgtgt gaccaacatc
    21121 tcatgatctg ctttattttt attattccag acatcatact gcatttttat cgcctgcatt
    21181 tttaacgact gcgcctgtaa tgcgttagcc aaatcctggg attctttgat atcctttgaa
    21241 gcctcaattc ggctacttaa actctgaatc tgagacattg cacttgataa ctgcttattg
    21301 atctcatttc cctgttcaat actggcagcc gttgacacaa tccgtgcttt acagagatta
    21361 tcattacgtt catagcccgt attacacata tcgaaggctc catacttgct gaacagattt
    21421 ttagcctggc tgctcaatgc accttcggga ttactggtaa aatcagaaat ataactgttc
    21481 ccctgcttat aaatatttgt cagttctgat tgtagattac ttagttcatt tgtgaatgcc
    21541 gcaatattcc ttatacctgt tgccgtggct aactggtctt tatatgcctg aatctgactc
    21601 tgataatgtt gcgcagtttc ggaccattgt ttgagtcgtt ctgtccatct tgcggcttca
    21661 acagcccatt ccggactggc atcaatagca accggaattc ctgcgctact ataaaatgaa
    21721 gccgtcaata atgatatcag catcaatgtt tttacacgtt tcataaattc acctgtcaga
    21781 ttgcccgttc gagatattca ggaacccagt catcaggctc cattccttca tgataaatac
    21841 tttcaaaaat ttccagatta tctgcactgg cagacaatat tttcagatat ccaccaagtc
    21901 ccgataaatc gagtgtcgca agtgctgaaa atgatttacc atcccccttt ttaagactgc
    21961 tttttttaat caggaactgt ctcgacattg gatcaagatt tttaacaata ttaaattctt
    22021 ctggtgtcag cttaagccct tccacataat cattgtaatc ggcatcaggg ttagccagat
    22081 aaatactggt gctgcatact tcaaccacag cccgtgaaat cttattcttc agtatttcat
    22141 ccggagactg agttgccgga ataaccagcc cgttcagctt acgaattgtt ttcagcttgt
    22201 tatagacaaa gtcgctgaat gcttcatcct gtagccattt ccagaactca tccaggaaga
    22261 taacaagacg ccgaccgtcc agaagctgcg taatgcgata cagcagatag aaagtaattg
    22321 gtgcacatac catcggatca tcaagaaact cggtgccatc aatgccaaaa ttattgacat
    22381 gctgaatatt gaatgtgtct ttagcattat caaaaaccca gccatgagcc tgaccattag
    22441 cccattggga caaacgaagg ataatcccgt tctcctgctc atcccgatca tctctctgca
    22501 taagatgctc aagcattctg gtaatgccat attcccgcat ttcgccagga ggaaaatcca
    22561 tcacagcatc aacactttcg ctaataagca atctttctct tgtcgataat ctttcaccat
    22621 ttctggtaca cagaatctcc atcagttgct tgacaaaaat acggttacgt tttgttgcct
    22681 ccagagcaaa aggattccat cctgtcggct caccgctttt tacggtgtaa tattccccac
    22741 caagcattcg gatacataat tcagcccctc tgtccttatc aagaaagaca cacgttaact
    22801 tcttattttt tgcagaatca gcaaaagttt cggggttatt gtatttctgt aatgaacagg
    22861 caagatatga cagaaacatt gtcttacctg aacccgccgt tcctataact ttagtattag
    22921 caagattctt ttcacctgtt tcatctttaa acagtactga gttatgtaaa ttcagataat
    22981 acgcctgttt gcttggtgtt ttgagaatag caaccgcttc tgtccagcag tttttatcgc
    23041 gtttcccctg gtagaaatta tggaatgatg ccagttcaac aaaatttaca ttcgataccg
    23101 gagataaacg cggccttaaa tgaaaaaccg ccggaagttg ggcaaaatat gccgctggca
    23161 atgacatggt tgacaatgcc ggaataatgc ccaggtcagt aaagtctgcc gtaattttac
    23221 ttacagattc gtcaagctcc ctgatactgt ccgccattac cattagcgtg aaatggtagt
    23281 aaccaaagga tatatcaccg gacacaatat cattttttgc cttttccagt tcctgcaatt
    23341 gagtaaccgc atcatcttct gtactcttta actgtttttc cgcacgttta atggtactca
    23401 atgcttctga tttgctcatg gatgtatatg aatgcgtaat aatatagtca gcatcagaat
    23461 actggagcac atcaaaaaca ccggatgcag tctcactaca gaaatcttta atttcaatag
    23521 aacgaaagaa tttatttcca tcaatgcggc atatctgtcc ggtatcatga ttaaaaaata
    23581 catccactcc accaagaacg ttatacaccg gagaatcagt gactctgatt ttttgcaact
    23641 tccctgtcag aagataatta tagaatgaca gttgagaaga aaataccttt ccgttctcct
    23701 catacatacc aagaagttta caggtaaatt tatcaagagc gccagagaat gtattaatca
    23761 tttcattcat tctcttcaca tgaatgttaa tatcatcttt cttttcttta atactttttt
    23821 tgcgtttttc cagtttttct acacgcccat ctggtctgta gatcagcgta aagtaaagag
    23881 tgttcccctt gaatttattt ttcttcatcg aaccatagta acaatctgat attatatcag
    23941 catatttatt acctgatttt gtggtaaagg catcataaaa actcgccctg catgaatggt
    24001 tataaaatga aacgggcagt ccggaaaatg aacgaacaag agtggcaacc tgtgagtcaa
    24061 tagtttctaa catctccgca gagattgact caaagttaat ccccatcagt tgccatgtcg
    24121 ctacataatc accgttcttt gttttgacaa tatttttatc aacatggctt gaatagggta
    24181 tatatttacc agtagtgatt cgctcattca gtttcatggc attaacaaac tcatcaattt
    24241 caacagcttc atattgtccg gagaggaacg ctcgtgcgcc aaaaaaacga ttacacactg
    24301 agtttccgag cattttcagc ttaagaaagt aaaggttaaa aatgtggtcg tcctgtttag
    24361 tgatcattct gagaacaaaa accgcgacag gaatagccag ccagatcagc ttgctgatat
    24421 aaacccccgc cagaaataac gcccctgcaa ccacagtaag agggacgaca ggaacaccca
    24481 catacatagc agggcgtgtc atcgctttat aaagtgtaga catactatcg tccccgcttt
    24541 attagttaac catcattgat gcaacttcag ccgcactggc gataacaatt gccccgatga
    24601 tgataggtga gcattcacga atcgtgcttc caccaaacag aaccttgtag ccgacccaca
    24661 gacaggcaat agtcaccgtg accagtgaaa ggccactaag ccctgtttta accttttcca
    24721 gcagtgtttc cgcttttgaa aatccatccg caaaggccgg tgatgcaact gttgccccgg
    24781 cgactgccat aactacctta tttttacgct gcattacagc agtgacagat gaactgatac
    24841 gattacatac tgatttctta aatgacattt tataagtcct gttaattaat aacttttgtt
    24901 ggatgtgagt tatcaacaaa agcagatttc agaatggttt cgggccagat aactgacgca
    24961 ttgtgtgaac gattttttcg ctgttctccc ccgttgcttc ttgtacctgg tacaacatat
    25021 tttttttcgt tccctgtata accaattcgc tcaacataac ttgtattatt aaattctttt
    25081 tcttttcgct taccgttact aaaatttcct gtatagtaac aactaagcgc attctccagg
    25141 ctcctccctc gtttataaca atccacgata atcttttcga aaacagacaa gttttcacac
    25201 gaatcaagga gtttttctgc ggacgtggaa taaaaagaaa aattactgct ggtaatctgc
    25261 atcaatccga cagaataacg tctttttctg ttttcaattt ctctgataac tgttagagct
    25321 tcctccttac ttttgggcat atgactgata acacttttgc catagctacc gcgttccctt
    25381 tcaggaataa tttcagccac agcataagga ttgaagccac tctcgacccg tgcaatatca
    25441 tttatcgtat ccggatgaac tgacgccgca cacagcaaca aggctgggaa taaagacgcc
    25501 atagctaacg ctccatatat ccatcaatac gcatactctg cattaataag taaataattt
    25561 gcttcctctt actaagcaaa gatgttttcg ttttctcttc gataaatgca ttcaacctgg
    25621 gatcgagttt tatcgtgaca taaacccctt tttccgatga cttatctgat ttctccttca
    25681 tttaatcaat ccactataag tgtgttttgg atttgtttta gatgcgaaca tgattcgcaa
    25741 aataacaatg ctcaacaata cgatcaaata acattgacaa aatggtcata ttatgattcg
    25801 tgtgatcatg caaaaaaaag cgcccatatg ggcgctctag tatgattgaa acattagtta
    25861 atcgaatgta gggactggag catccttctg agactgaata aacaatgctt gtttaacatt
    25921 cttacagttc tgagaatcag agccagactt ctcacactct gcctgctttt gtttagcttc
    25981 cgtaagatgc tgcccccacc aatccacact ttttacttct tcactacaac caacaacgaa
    26041 gaacggcaaa gcaaaaagca gatatttttt cataaattcc ccctctcact gatcctggaa
    26101 agacttgaca cgagaagggc attagtccga atgagtacca gtgttctgat ccctgccaac
    26161 gagacacctc ccagttcagc tcttacagaa tcgagatatt ttctgacagt tgaaggcttt
    26221 agtcctttga aatcagcaat ttcattcagg gtatagccat aagcgtacat cagaataatg
    26281 tctttttgtt gctcactcaa atgttcttca tcactaaaaa tttgatgaag tccagaaatg
    26341 cagatagcat catgctcagt catgataacc tccctcgtag gttgttgtga tcagcaggtg
    26401 agcaaagtag ccgctttgtt cacctgcgcc aaaatcaaat taaaatccca ggcctttcca
    26461 gttcctctct tgctgtattc ttagtttttt atgttcttct gaatcctttg taaacccgtg
    26521 ttcaagagca aacccgatat tgtgaccttg ctcatgtttt ctggatagct gctttttaac
    26581 gtcgctctct tccggctgcc tggtttcacg ctcatgaacc tgacgttctc tgttccgctc
    26641 aagggcaata ttttcaatct gccagttatt gcgatgcgtt tccctgtagc ctgcaacagt
    26701 tccatcatca ttaaacattg gactacgtac aagcgtagga gccagttttt ttactttgat
    26761 aagcgttcct ggctggagct tttcagactc gaaatgattt ttcaggtctt taccccaaat
    26821 cgtaacctgt tttccacctt ttaaagtttc ataagtgagg aaaggtgttc gtttttcccc
    26881 tgccttattc tgatatgaag tctccccaaa atccaccacc ttgtaaacat tccggagtct
    26941 tttcggattt tcagcctgta atcgctcaat ctcccgttta cgttcgggat cttttttcca
    27001 ggtagcggta acatcatatc ccataccttt cagttttcta tgaaaaccgt ttctgaactt
    27061 cctggtttca gatttagtaa gtcttaatct tcttcctgtt tcttcatcac gaagtttaat
    27121 attaacatgt acatgaggat gatcttcttt atcatcatgg tatacggcaa cgaaagcatg
    27181 gtttggataa gtctctttaa gaaattctac cgtagctttc agagcgtctt ccctgcttac
    27241 tccagcttct ggtggtggtg aaaagaccat gtttttcaca tgatcgatgt tttctccacg
    27301 atatgtcctg gagtaatcat ttcctttaga taaagttgaa gtaaactccc tattaaagtc
    27361 ttctcctttc cctgtttgct ctgaaccttt tccatcataa cagtaagcct caagttcacc
    27421 attacgggta atgtaatcaa taccattttt gatgcctgcg gctgttttac ctgagccagt
    27481 gattttaaaa gtgacttctt ttgtaggtgt ccaggtatat gctttcttgt ccgcaccatg
    27541 tctgacttta tgattaaaag ccgatttact ggcatgtata tgtcttcccg ataacttagg
    27601 agatttcgga tcacgcccag tccctttagc gcgtttaata cggtattcct gttctacata
    27661 cacacccata aatcacccaa atctgttaac aacactcttg gttaacgttt caagttttga
    27721 atcaatttgc ttacacagtt caatcacttc aataacgtct tttctgaaat ctggatcgtt
    27781 aaccgtacag aatctttcac cttttatgat aaaatgaatg ttgcgaccaa cacgatctac
    27841 agcagttgat agttttttaa gttccttaac ttcatcaggg taaagacaga cttcactctt
    27901 taacaaagac tgacgcacac gaatagcaat ttctctgctc atgctcatgc cgtgaagagc
    27961 agcattacgt ttaacaagtt ctatttcatg agggtaaaga cgcactgata ccagctttgc
    28021 tggttcatta ttaactggga tgttaacagg cttggtttca atattaagca cgttatgctt
    28081 agcaaaagca ttgatactgg taaatccact taaaatagcg ttatgttctg caaattttaa
    28141 ctcatcatca cttagcctga acgctatcat cttcataagt caccccaaca gagcctgcgg
    28201 caggcacagg caaaaacatc gtttttggac aatctgattc aaatgttaac atttgacatc
    28261 ggattgtcta tcctgcattg attgtaccat atgtggcact gtgcctggct ataaaatcgt
    28321 cgctgcatat gtccagattt cgttgctgaa agattctttc gtcttcgacc atcaggcaaa
    28381 cgtatagctg aaagatttgt gaaagaaaaa acaggcctgg cagggctggg aattgttacg
    28441 gctgaagccg taacgctttt taagtcctcg ctgcgctgcg gggcttccgg cgcaaagcgc
    28501 ctcccatgcc cttacagggc ataaaaacaa gggcaattaa gcccctgcgc gatgattgct
    28561 gacttctttt tccagagcct tattaacaaa ggcattcaac gataaatctt cttccatcgc
    28621 catttctgct acccgacgat gcagttctgg atcaagcctg acgttaaaca cgcctttaaa
    28681 cggggtatca ggttcctttc catcctccac acaagactgt aaatacagat caacagatgt
    28741 tttaaactcc tgttccagtt cagctaatgt agaagcctca taagttacca ggtcccgaat
    28801 aaacgccagt tttccataca ggacattatt ttcaaaatcg ggttcaaccg tgcctaaata
    28861 tcctttatat tttaaatgtt tcataataat ccagcctctt tcagattctg tttaattgct
    28921 ttcagcgtac cacctttgat ataactttcc ggatgtggac gatgcattaa tatggtgtga
    28981 ttgatttcag cattgaaaaa ccgcactctt gacccctgca tttccttttt gacatatccc
    29041 aaagaggaaa acaaaacgac cagttcatcc cattcaaacg tttttttact gtttaaaaac
    29101 tttgccagta gcttatctgt tttccccata aatccatccc ctatagatat gcaactaatt
    29161 atagttacac atggcatttt tgtcaaaaaa tacaaagggg cagaaagccc ctttttttat
    29221 ttaaaacatt tcataccctt gcaagtagtt taaccaccac cggaattgat cccattcgct
    29281 aaatttcatt gccggaattc tggtttccca gcctttgaca agggaatcag caagctgtac
    29341 gatctgccgc gttgacattt aaaaacctca ttcagttttg attgtcgata acgtgatcag
    29401 gttggtggaa caacctgatc acaccttgaa tagtcagtca ttaccctcct tcttttctat
    29461 agttactgtg tatccgtaaa gagtcaaaat gcgataagca tccaacgcct cacgctcact
    29521 tttaaatgtt ctgacttcgt gtaatccttt acctttatca agggatacac aaaactcata
    29581 atcttcttct acttctatct ttttaattaa tttatcaagt tcggctaatg ttcgttttgg
    29641 ctcaaaaaga aatgtgcatt gtacaatggc gtttaaatct tcccgatcaa gctctaacag
    29701 agcatcatta taagcagctt taaaacagcg attattacgc agatcagatg caaactgcat
    29761 tgcggcttgt tttaacgttt tcatgaattt cccttgcatt gatgttaata gacaatttca
    29821 gaatcaatat tgaaatttcc agaaaatgca gggatgcccc tgcattcata atgcttaaca
    29881 aagacactca ataaaatctt taaaactcaa gcattcatcg ccatctttta atgaatcaaa
    29941 atatttttca tattcgtccc tgtagaaaag gactaaatca acatcactct gcttaagttc
    30001 gccaaactga ggaacaattc cggctttata gtcacgaatt ttattgttat cagtaaatat
    30061 gacaacatac tgttgtccag tatccttatg cataaggata atagtgcaaa gcgttactcg
    30121 ttcgaatgtg aaaacatgat tagtggttga agtaaaaaca gatgagcatt tcattttaaa
    30181 tctcctgccc tgctgggcta ttgtgagagg ggccattccc ctttcgatga aacaataata
    30241 cgacctttaa gtcgtatttg caagttttct cccgtttttt tactcgataa gtgattgtta
    30301 tcacgttttt taatccgcgt aagcggatgg aaggggcgaa cgaaaatacc agggcagcac
    30361 aggagccaca tcgccccgaa gcgcggcgca gccgctgacg aacgtaccag ggtgcacagg
    30421 ccatcccttc accctgcaaa gcccaactga ccagcaggcc atgattatgc tgatttgcgc
    30481 cgcagaatgc cgcagttagc gcgagcgcaa gcgagtttac cccgccctgg tgcattgcag
    30541 catggcgggg cgctgtactg cgcgtgtgag cgtcagcgag ctacgagcgc aactccaggt
    30601 actaatataa aaccatcaca ggtcatttta ttttgactcc cttttgcaga gcacgtattc
    30661 aggatgttct cctgcaagta acaaaagaaa ctcaaactca accagtgaca gactttgact
    30721 gttttgagta ttaacttcct cttttttctg ccaggttctt agcccaacac cataaatatg
    30781 actgcattcc ttttgtgtta atcctgcttt taaacgtaat ttttttacat tttcaggtgt
    30841 attatcgggt ttcatttaac ataaactcct taattaaatt cttaactggc gtctcatcgt
    30901 cttcccttaa tccggcacac gtaaaatcaa tatgttgtaa ttcattctca ttcagtacag
    30961 catcatacaa tgtaattttc gtagttttgt tcccgatttt aacatttgtt ctggctttta
    31021 tcctttttgt aagcctgtaa ttgtcacctt ctttttcaag aaaataagtc acatcacctt
    31081 tattttttct cataactgtt tcaaataccc tgtaatttta acaagttgat ctatactcaa
    31141 gccccgaatc tgtaaatcat aactgtcgcc ctgttcggtg actttaccgt tcaatccgtt
    31201 ttcagcttta aagcctgtca atgccccata ccagctttca agctggacaa gttgcgataa
    31261 catacctttc aggatcagaa tttcgtcctt tttttccacc tggtgtttct catactcaat
    31321 cgcctgtaac acctcctgcg aagcatttac cagaattttt cgctcgatat cggctgcaat
    31381 atcaacggga ttccgttttc tggataacgt gcaaacatga tgcggactac gccaggaacg
    31441 actatccaca ctccccacca cagaaaagcg gtctttttcc atccgaatat gcacagagta
    31501 atttttaaac tgcggtgacg tcagttttat acgagacgaa caatcatcaa gtttgttcac
    31561 gcgccagccg ttccccagga tacggcagac aacttcaaag acagggtgat attgttcaaa
    31621 aaaagagttc atctgtttcc ctttttgcta cgtggctgct gttcccgtct ttttgggttc
    31681 gatgccccaa aagacgggct ggctataata tcgggggctt ctcgcccccg ttctggttac
    31741 gctctggttt ccacgcgttg ccaccctgtc gccctgcgct gtccggttgt accgtatttt
    31801 gcgcggattt cttctatcgt gtgttcttca cgattccagt aacttttatg ttcgtctgga
    31861 cgataaaacc attgtttttt ctttgccgcc catttacacc cgatttcttt taaagtttcc
    31921 ttatgtgtaa tggtttctcc actaatccag acccagttac ctatcacttc aaataccaga
    31981 ccagataaac cagaaagaac gtttaatact ttttccaggt catcaccgta attatatcgt
    32041 gcatgttcat cagtgctctg gaactgattt attttatcaa tatttgccat caatacatca
    32101 aaagctgcat ttaccgcttt catcagttca gcccctaacg ggttacgatc tggatgatat
    32161 tttaaagcgg cttttctgta tgctgctttg atatcttttt cagttaattc gccggataat
    32221 ccaaaaacgt ttaatgcttc ctggatattc atttttttaa tctcctgccc tgctgggcta
    32281 ttgtgagagg ggccattccc ctttcgatga aacaataata cgacctttaa gtcgtatttg
    32341 caagttttct cccgtttttt tactcgataa gtgattgtta tcacgttttt taatccgcgt
    32401 aagcggatgg aaggggcgaa cgaaaatacc agggcagcac aggagccaca tcgccccgaa
    32461 gcgcggcgca gccgctgacg aacgtaccag ggtgcacagg ccatcccttc accctgcaaa
    32521 gcccaactga ccagcaggcc atgattatgc tgatttgcgc cgcagaatgc cgcagttagc
    32581 gcgagcgcaa gcgagtttac cccgccctgg tgcattgcag catggcgggg cgctgtactg
    32641 cgcgtgtgag cgttagcgaa ctacgggcgc aatgcaggag aactaacaga acctccctaa
    32701 aacgctctga atcgcatttt aagcgatttt tttcatttcg catggttttc ctcatggttg
    32761 tatcgaacga agcggcagag cgcgattcag ggcttcttag tggaagatcc aaaaaggatc
    32821 aaataacgga tcatatgatc tgaatctctc tggttttgag aaaggagata ccgctcgccg
    32881 cagccgaacg gcaggagcgt agcgactgag tgagcgagga agcggaattt ttgcgatgtg
    32941 acattaggat cagtacgcac gaatattata tttatttcaa taagttaaag ttaactaggg
    33001 acaaatttat ggtcttgaaa attgagatac ataaggcatc aaatattttt ttgatgattt
    33061 tatgttattg aaagttatga gttttaatga ttgatgatgt ttgttttagc ttgcgggtaa
    33121 taatcatcgg gggacagatt tatggtaagg aaccatcatc gttgctggtt ttgttgagtt
    33181 atccacagtt cctgaatatt cgcacgcatt aaaagcctta tcttttcttg tttttcttaa
    33241 aaacttaaaa acttagagta gctctaattt attgatttta agcgtgtttt ttgtctaaac
    33301 atgagagctt cctcggttaa acatgataac ttcctcggtt aaacatgaga gcttcctcgg
    33361 ttaaacatga gagcttcctc ggttaaacat gagagcttcc tcggttaaac atgagagctt
    33421 cctcggtgat atccacaaaa tgtgtcataa gaatactaat tcgttgttct ttctggtgaa
    33481 tctattttga atctgttgtt aatctgcctt gaatccagtg tggattttga gcatggatta
    33541 cctttgtgag ataaatcaca gatatgaaac atgagaagat actcggttaa acatgatatt
    33601 gattgtgttg taatatcatg tttctggtgt taaagtctga ttatcaagag tgttggaaca
//
