LOCUS       NZ_LR890709             9294 bp    DNA     circular CON 18-JUN-2023
DEFINITION  Klebsiella pneumoniae strain INF305 isolate INF305 plasmid 8,
            complete sequence.
ACCESSION   NZ_LR890709
VERSION     NZ_LR890709.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA3357165
            Assembly: GCF_904866445.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Hawkey,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2020) THE UNIVERSITY OF MELBOURNE, 30 Flemington
            Rd, Australia
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/18/2023 15:46:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,113
            CDSs (total)                      :: 5,984
            Genes (coding)                    :: 5,827
            CDSs (with protein)               :: 5,827
            Genes (RNA)                       :: 129
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 74 of 157
            Pseudo Genes (incomplete)         :: 86 of 157
            Pseudo Genes (internal stop)      :: 29 of 157
            Pseudo Genes (multiple problems)  :: 28 of 157
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR890709.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="INF305"
                     /isolate="INF305"
                     /isolation_source="wound swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="8"
                     /geo_loc_name="Australia"
                     /collection_date="2014-01"
     gene            complement(join(8995..9294,1..1665))
                     /locus_tag="JMX64_RS30375"
     CDS             complement(join(8995..9294,1..1665))
                     /locus_tag="JMX64_RS30375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(3146..3295)
                     /locus_tag="JMX64_RS30380"
     CDS             complement(3146..3295)
                     /locus_tag="JMX64_RS30380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(3380..3637)
                     /locus_tag="JMX64_RS30385"
     CDS             complement(3380..3637)
                     /locus_tag="JMX64_RS30385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(3647..5332)
                     /locus_tag="JMX64_RS30390"
     CDS             complement(3647..5332)
                     /locus_tag="JMX64_RS30390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            5735..6154
                     /locus_tag="JMX64_RS30395"
     CDS             5735..6154
                     /locus_tag="JMX64_RS30395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            6460..6723
                     /locus_tag="JMX64_RS30400"
     CDS             6460..6723
                     /locus_tag="JMX64_RS30400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            6713..7012
                     /locus_tag="JMX64_RS30405"
     CDS             6713..7012
                     /locus_tag="JMX64_RS30405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(7074..7451)
                     /locus_tag="JMX64_RS30410"
     CDS             complement(7074..7451)
                     /locus_tag="JMX64_RS30410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            7520..7699
                     /locus_tag="JMX64_RS30415"
     CDS             7520..7699
                     /locus_tag="JMX64_RS30415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(7727..8257)
                     /locus_tag="JMX64_RS30420"
     CDS             complement(7727..8257)
                     /locus_tag="JMX64_RS30420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(8264..8995)
                     /locus_tag="JMX64_RS30425"
     CDS             complement(8264..8995)
                     /locus_tag="JMX64_RS30425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     BGC             1..9294
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          2465..3043
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(8268..8995)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 gcgctccacg tccaccctga tttccccggt ctgccccgcc gcccactgcg cggactccag
       61 gctggccgcc cggtaaaacc agcggatcgg cgtgttatcc agtaccgtgg ttttcacaaa
      121 ttcagcgggc agatcctgcc cgcactgccc gaaatcgccc agcgactggt gcgcgagcaa
      181 cagattgcag tcccggctgc gcagcgtccc cagtgcgttc agtacatact tcgacagcag
      241 atatttaatt tcatcgagca tcacgctgac gtgtggccac tcccggaact cgtcccgcgc
      301 aatgatgatt tgcgcgcagc gggcaaacag cattttttgc acacggatca ccgcctcgtc
      361 gtccatcgag ccgataacgt acaggcagcc gccgccgttg ataatccccg ccacatcgat
      421 gccactgtcc gtctgcagga cgctcaggtc agcgacgttt tccagcctag tgatcaaccc
      481 cttcacgtcc tttttcaggg cctccggcag cgcgtacgcc gccgccagca cctgctgaat
      541 gtttgccccc tgcggaaact gctccgcaat cagcttcgcc gctttctgct cgctgatgcg
      601 gtagtggtcc gccacgtcgc cggtctcgcc caggttaagc ccggcaatca gcaggttttt
      661 cagcgcgtac tggtcgagat cgcggaacag attcagctgc gccggtttcc ccggccgcag
      721 atccagcagg gtgaagtccg gacagtgcgc ccggaagacg tgcggcgccc atgcgtcccc
      781 tttggggtcg aagtacacca ccgcgtcccc gaaatcgcgt acgcagcgaa tgagcgcgtt
      841 ggtggccatc acgctcttgc cgctcccggg caggccgagg atctgaatgt tggtcttgcg
      901 ccaggtatca cgcggaacca gcaccggctt gccctgctca tccttaccca gaaacaccgc
      961 ctgctcctgc cgggcctgct ccgaggaaaa atcggccagc gcattaaccg gtaccggctc
     1021 cccgaaatgc aggtggcgca cgtcggtcat ctctcctgtc cgctggctgc tgcgccggct
     1081 ctcctgattc agtttcgcgt tcaccgcctc gtcagcagcc gcaaaatgac cgtcaagcag
     1141 caggaacgcc agcagccgcg ccaacacaat cccgacagcc agcccgcccg cgcaccaggc
     1201 aatcccgaac aggttagccg gctgcagcag gtaataatct gcgtttgcgt agaggtccgg
     1261 acgcaggacg gtttctcccc agctctcgat aaacacggcg acaaccagcc cccccagaag
     1321 ggccagaccg gccgcgccgg tcagccagta cgcgtagttc cagacatgtc gacgtgccct
     1381 gaccatccgc ccgggcgaat ccagcgaggc cagcaccgaa aatggcgctg gccgtttatt
     1441 atcgcgctta tagcgatcgg catactcccg tcgctcctta tgactcagcc ccacaaaacg
     1501 catccgtccg gcccaaagtt cagccagacc gaaaaacagg ccgataacta ggaaagcccc
     1561 ggccagaccg taatactcct ggtacagcca gctgacccac ggataaatct gccgggccag
     1621 ctccggaatg tgccacttcc aggcaagcga atccgtatta aacatgttct ctctccttca
     1681 gacgatggtt tgccggcgtg atgtgcagcc cccgctgcac aagccgcgga catgccccaa
     1741 ggcatggcgg cggcggtcac gtccgtggtg attgcgttca gctttcacca cggaggccag
     1801 cctctttccg ccccatgcgg aaaaggcgca gccccggagg aacaacgagc acgccccagc
     1861 gtgtgagagg aaaaggcggc accccagtgc ggtcttttcc ggtgttccgg cccccgtcag
     1921 agttcgccat agcgagcggc tgaccacccg caaaatcagg agcagctttg ctgcttcgcc
     1981 aggtgcgtcc agcaccgtgg atttttgtgg gtggtcaggc gtgagcctga cgggggccgg
     2041 gtgaatttct ggcgtggccg gcgtccagcc ggacggagcc agaaagaggg ggagagaccg
     2101 tgcgtcggtg gcgtccagcc agcgtaagca ggggatatcc ccctgaggtc agccacgccc
     2161 tcgcggggat gacctgtatt tctccgtaag gagaaaaaag caacagagat aggttaacgt
     2221 aaaatgttca gcgaaaaacc gatatgattc acctatcctg gtaatttatt atcagggaat
     2281 ataaagactt aatcagggga caatatgcca catcagcgcg tccggtgtcc gtcttgtagg
     2341 tgccggggaa attgcgcctc ctcgctcact cggtcgctac gctccggccg tgagactgcg
     2401 gcgggcgctg cggacacatg caaagttacc cacagattcc gtgaataagc aggggactaa
     2461 catgtgaggc aaaacggcaa ggccacgcag gtggcgtttt tccataggct ccgccctcct
     2521 gactgagttc acataaacag acgctttttc ggtgcatctg tgggagccgg tggctcaacc
     2581 atgaatcagt caggagtggc gaaacccgac aggacttaaa gatcatcacc gtttccgatg
     2641 aatcgctccc tcttgcgctc tcctgttcca accctgccgt ttcccggata cctgttccgc
     2701 ctttctccct tgcgggaagt gtggcgcttt ctcatagctc acactctggt atctcggctc
     2761 ggtgtaggtc gttcgctcca agctgggctg taagcaagaa ccccccgttc agcccgactg
     2821 ctgcgcctta tccggtaact gttcacttga gtccaacccg gaaaagcacg caaaacgcca
     2881 ctggcagcag ccattggtaa ctgggagttc gcagaggatt tgtttagcta aacacgcggt
     2941 tgctcttgaa gtgtgcgcca aagtccggct acactggaag gacagatttg gttgctgtgc
     3001 tctgcgaaag ccagttacca cggttaagca gttccccaac tgacttaacc ttcgatcaaa
     3061 ccacctcccc aggtggtttt ttcgtttaca gggcaaaaga ttacgcgcag aaaaaaagga
     3121 tctcaagaag atcctttgat cttttctact gaaccgcgat ccccgtcagt tcagaggagg
     3181 acgatggtgc caccgttcca ccctgaacat cccggatata gtttgcctga catgcgacca
     3241 gaagaaagcc tgaaaaaatc aatataaaaa gaaaaacaac ctttaccttt ttcatatacc
     3301 ttccctgtat ttaaaaaccc cggtattcat ccctgaacac cggaagtctg tatttcaaat
     3361 catccttgat aacttttgct taccagttac catcccggta aacaaaggat acaaagtaat
     3421 caaatttact aatatcgatt acatttttaa agtgtggctg taatatcgaa acccatgatt
     3481 tttcaacatc aaaccaacca ttattaatat tatcctttaa aggcatcccc agactttcaa
     3541 tgacagaacc atcatcaccg aagtcttttg agtattcacc acctttaaac tcttcggttt
     3601 tcttatcaaa ccaatgaata tgtaatttaa gccccatatt tacctcttaa agatattttt
     3661 taatgtttcg ttttggatcc ggccctttaa cctgcttacc cgtttttgga tcgaatgccc
     3721 cgaggtgttc gccatcactg gcgcggtacc cttcaagctc accgtgctgg gaatcccatt
     3781 cataaatttt acgcttttta tcaccatacc atcgggcccg cttaccacca ccaccttgtt
     3841 taggggtttt aggtttaccc tctttcaact ctcccaaccc cttaatatct tcagtcttgg
     3901 gatcaggaaa ataatcatgg ccgtaatctt tagttccctt acgaggtttt ttcttttcct
     3961 catttaattt attttctgca tccttcgctt ttttctcctt ttgtttccgg ctctccatcg
     4021 ccccggaaag cgcagcctta tccctggata aggattcatt catttcgttt aaagatgtct
     4081 gggcagcttt taatttctca ttctgattct gaatatcctt atcaagatag cgaacctgat
     4141 cctgccaccc ggagccatat tcatgaggcg ggttataagt cacaaaatca tctttatttg
     4201 cctctgcctc ttttaccttt ttatcggctt cctgaacagc agcccttgca ccggggatcg
     4261 ccttctctgt cgatgcaatg cgactgttta aggtcgcaat atttttatct tcagcatcca
     4321 gctcagcttt cgctttatca tactctcttt tcagcccctc ttccgggtga gcagcgtccc
     4381 atgcctgctg gcgacgcttt tcttcctcca gacgctgttt tacctgtgcc ggagtaagaa
     4441 catccgtcac cgacacatag accggtttct gtccgctctc tttcgggaaa cgaataacgg
     4501 cttcacggga gttaccaccg gccgtaaaac cagccggacg tgaatcacct ttttcagcaa
     4561 taatgccttt tggcggggct ttcgcggccg gaacaccttt aggtacgctc acctgcagag
     4621 acgggagacc cggaatcgac acactgaata cccccggacg ttttgtcggt ttcgcatcca
     4681 ccacaggaac actcattggc cggccggtga caaccgcaat atgctgccgc tcgtccttca
     4741 caatatccgc cacacgttta gtgacgctga ccgtcgcctg gtccagcggc agggagctga
     4801 ccggcgtctc cgttaccgtg tctgccggca atgacgtcac gatttttgac atcattttcg
     4861 gatcatcttt tgctatctca gaaggcagca ctccgtaaat cgcaatcccc cacagaccaa
     4921 acttaaacgg acctttcagg gcagccagca catcagcaac agcggccgac aacgcatcgc
     4981 cggaaacgga taaagccagt ccttcagccc ccggagtggc caaggcaggc agaccgaagg
     5041 ccatcgcggt ggccgaagac tgtccgccac cagagctccc gctatgattg ccgctgttac
     5101 cgccattacc accgggttta ctcccgccgt taccaaactc ccccgggtta tagttatgaa
     5161 tatccccgtt aggtgtatgc gtcgtacccc agcccggccc gctgtttgga tccgtaccac
     5221 cacctgatga agggccacct ttacctgatg taccgttcac attcccactg gcctgaccac
     5281 cattgtgtcc cagacctgaa ttacccggac ctcgtccgtc tccgccactc atatactttt
     5341 cctctttgac ttttaaaaca ataaactaaa ataaaatact gtacatataa ccactggttt
     5401 tatatacagt ataaaaatta cgctgccttg tttttcatgt caagtctgta aatttgcgtt
     5461 tttgtgaaaa tgatcaaaaa aacagccact cacaccatgc gcaatcccct ccagatgcaa
     5521 caaaaaccag cacaaacggc gccgttctcc ggcctcagta tgttttactg aaatcattat
     5581 atgagatacc agaaagcccc ctccgggaca ggaaaagaaa cggggggtct ggttcgggtt
     5641 gttcggtcac tgaacacggt cagaaactga tgataagata gcctgcggat atataactca
     5701 atgagaaaaa agaattaaag gtaaggagac gctcatgaga cgttccggca gcaaactgtg
     5761 tcttatcgcc atgataacag cgacagcaac tctcactgcc tgtgctccaa agggcagcgt
     5821 ggaacagcat acccggcatt acgtatatgc ttcagatgac ggttttgatc ccaatttttc
     5881 cacccagaaa gctgacacaa cacgaatgat ggtgcctttt ttccggcagt tctgggatat
     5941 gggcgcaaag gataaagcga ccggaaaatc acggagtgat gtgcagcaac gcattcagca
     6001 gtttcacagt caggaatttt taaactcact ccaaggcaca acacaatttg cgggtaccga
     6061 ttaccgcagc aaagacctca caccgaaaaa atcaaggcta ctggctgaca ccatttcagc
     6121 tgtttatctc gatggctatg aaggcagaca gtaagtggat ttaccataac gcgtcattac
     6181 gcgcaccgct cagacgggct cagggcgttt ccggcggcta cgggataaaa caggcaacaa
     6241 cccccccgga aaactgccgg aaacgcgccc gataaatttt atcctaatgc atgcctatgc
     6301 acgcaactgc atggcatatg ttttgacgta aaatggatgc cgtaagccct tttttaccga
     6361 ctttctgctt catcagcctg actgacacga ccatattctt tcagaccgcc ccctgctaaa
     6421 cttccttcat attgccgcat taacccggga ggctccgcaa tgagcaacac tacacactac
     6481 gaaaacgcca actttcttcg ggaactggct gaaagcctgc cccgcatact gccggaaggt
     6541 ggcccggaca aagctgcgct gttgcagcga ctggctaacg aagaactggc ccaggcagag
     6601 tatgaagatc aggttcgcgc caaagtgacc gccgcccgtg ctgacacgcg tccgggtatg
     6661 accacggaac aactccgcca gcgcctgcat ggccgttatc aggaactgcg cgatgccgta
     6721 tgacgtggaa tggaagcagg gagccatcga ggatgtaacg acgctgtttg actatatcgc
     6781 ggaaaattca tccctgtggg atgcgcagaa cgttaccgac cgggttctcg ctgcggcgga
     6841 caaactggcc gacttcccgc gactctatga agtggactca cgctatggcg aggacgttcg
     6901 ccggatcagt ctgatgggac agcatgtcct ctatgatgtt gatgaccaga ccagaaaagt
     6961 ccgggttctg gccgtggtcg gccagcgcca gaatccccat attgttctct aataaccggt
     7021 gacggggacg caattcattg cgtggccgtc gccggttgga caagcacagc gcgtcagcgt
     7081 tttccccacg gccaccaccg gcgcggtgtt ccggccgggg tctctgctgt ctccggtttg
     7141 tgttccagca gtctcatgga ctgcatttcc tgccgtagcc cggccacctc ctccctgagt
     7201 gcttttatct ccgcgatcaa cgcgtcggag gccatttttt cagtctcacc cgacagtctc
     7261 aactcgtccc gctcgtgagt ctcatcctgt cttaactcac cgtacacccg gataagctcg
     7321 ctggtatcca ccacccggcc gccatcagct tccgtacggt atgatacgcg gcctttcgcc
     7381 atatcccgat acagggaact tcgggcttta cccgtcagtt ccgtcgcctg tctcaccgtc
     7441 acccacgcca ttgtctcacc ccgctatttt tgagacagta tacctgacag gcgcacacca
     7501 tgcccggaag gaaagaatca tgacaaaaca ggaaaaaaca gccctcaata tggctaaatt
     7561 tattaaggag cagtcgctgc tattgctcga taaactgaat gagctggata tggatacccc
     7621 ggccgacatg tgcgagcggc tacacgagga tgcggaaaca ctctggcagg tgatgcggga
     7681 taagctcggg gaggaataac agcaccggca tggccggtgc tggcatttat tttttgccga
     7741 acggccacca ccggcgggca ggtttgtcct ccggcagttc aggtaccggc acgttaaaat
     7801 agcggctgtt atattcccgc atcagctccg ctttcagctt ctcgttcacc gcgctttccc
     7861 cgtgccgctc actcaccacg tcaatcatcg cgttaatctg ctccggtgag cacttcccgg
     7921 catcaaccac ctgcacaccg ttctcgatgg cgaaccgctc caccttgcga tagaggtaat
     7981 cacacagctt cattcctgtg ggtttgttcc gttcccattg cggattttta ccagtgaaaa
     8041 agtacgtggc tttttcgtcg ctgttgagcc gctcgtcata catcccgatg gatttcatca
     8101 tcgccagatg ctgggcccgg tcgacaaaac agaaaacata cgccccggtc tgccaggcga
     8161 gcaccaccat atcttccaga tgctcgctgg tcggcatgat gcagcgctcg ccgttccggt
     8221 cctccgcgtc ttcaataaat accatgtaca gcgccataat ccctcactcc gttgtcataa
     8281 atttaaagca cgcaaacaac cgttcacgat ccagctctgc cgttttgcgg gcctcgccgg
     8341 tctgtgggtt cacgatttca tccaccgaca ggattgcccg ctgcaccctg acctgcgtcg
     8401 cccggtccgg gcagatgtac cagatttcat cgatgccgtt agctttgcgg ttgaacagat
     8461 acccggacac cacttcctga taccggcgac ggctcttgac ggtgcgctcc acctcaaacg
     8521 ccaccgtttt accgtccagc tccgccaggg cgtccggcac tttcatgcct ttaagactca
     8581 gacggtgcag aatgcgccag ccggtggccc ctctggcttc catatcaagg cgcagggatt
     8641 gcacggccag ccggtgcggc agatgtgctg ccgacaccct tgacggctga aacggaataa
     8701 catccgccag cggttcgtcc tcgtcgaacg agaacgccac gccatgcggc gtcagccccc
     8761 acacgctgac ctgacggccg tccaccggat atttggtccg gaccagcagc cctttcgcca
     8821 ccaggctgtc gaggaagcgg tagaccggct gcaccgccgc aatccccagc cgccgcgcaa
     8881 ccagctccgc cgtggaacac agctcttccc gcaaccagcg cagggtcagc cgggttttct
     8941 ccgcgttccg cgcctgtcgt ttcgcgtggc tgacgttgta cagctccagc gccatcagta
     9001 aatccccgca aaatcatcat ccgctttcgg cccgccgccg tcggccgggg gccggaactc
     9061 cgccagggga tcggttttcg ccagcaccgg gaaacgctgc aacgggattt cccggcgctc
     9121 aacccgcagc ggactgctga acgccatccg ggccacaccc agcccggtca tgaccgcgaa
     9181 cccgtccggc aggtgttgca gggtgttcac gtcaaacagc ggccgcgcct ccttctggat
     9241 gaagctgtcc ccgctgatat gctccacgtt ccccgcctcc cggctggcac ggcg
//
