LOCUS       NZ_LR890433             9294 bp    DNA     circular CON 10-OCT-2022
DEFINITION  Klebsiella pneumoniae strain INF298 isolate INF298 plasmid 8,
            complete sequence.
ACCESSION   NZ_LR890433
VERSION     NZ_LR890433.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN06112224
            Assembly: GCF_904864465.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Hawkey,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2020) THE UNIVERSITY OF MELBOURNE, 30 Flemington
            Rd, Australia
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/10/2022 08:37:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.3
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 6,105
            CDSs (total)                      :: 5,976
            Genes (coding)                    :: 5,822
            CDSs (with protein)               :: 5,822
            Genes (RNA)                       :: 129
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 75 of 154
            Pseudo Genes (incomplete)         :: 82 of 154
            Pseudo Genes (internal stop)      :: 29 of 154
            Pseudo Genes (multiple problems)  :: 27 of 154
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR890433.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="INF298"
                     /isolate="INF298"
                     /isolation_source="wound"
                     /db_xref="taxon:573"
                     /plasmid="8"
     gene            complement(join(9084..9294,1..1475))
                     /locus_tag="JMX68_RS30360"
     CDS             complement(join(9084..9294,1..1475))
                     /locus_tag="JMX68_RS30360"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            1878..2297
                     /locus_tag="JMX68_RS30365"
     CDS             1878..2297
                     /locus_tag="JMX68_RS30365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            2603..2866
                     /locus_tag="JMX68_RS30370"
     CDS             2603..2866
                     /locus_tag="JMX68_RS30370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            2856..3155
                     /locus_tag="JMX68_RS30375"
     CDS             2856..3155
                     /locus_tag="JMX68_RS30375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(3217..3594)
                     /locus_tag="JMX68_RS30380"
     CDS             complement(3217..3594)
                     /locus_tag="JMX68_RS30380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            3663..3842
                     /locus_tag="JMX68_RS30385"
     CDS             3663..3842
                     /locus_tag="JMX68_RS30385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(3870..4400)
                     /locus_tag="JMX68_RS30390"
     CDS             complement(3870..4400)
                     /locus_tag="JMX68_RS30390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(4407..5138)
                     /locus_tag="JMX68_RS30395"
     CDS             complement(4407..5138)
                     /locus_tag="JMX68_RS30395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(5138..7102)
                     /locus_tag="JMX68_RS30400"
     CDS             complement(5138..7102)
                     /locus_tag="JMX68_RS30400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(8583..8732)
                     /locus_tag="JMX68_RS30405"
     CDS             complement(8583..8732)
                     /locus_tag="JMX68_RS30405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(8817..9074)
                     /locus_tag="JMX68_RS30410"
     CDS             complement(8817..9074)
                     /locus_tag="JMX68_RS30410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     BGC             1..6475
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          7902..8480
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(4411..5138)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 ccctctttca actctcccaa ccccttaata tcttcagtct tgggatcagg aaaataatca
       61 tggccgtaat ctttagttcc cttacgaggt tttttctttt cctcatttaa tttattttct
      121 gcatccttcg cttttttctc cttttgtttc cggctctcca tcgccccgga aagcgcagcc
      181 ttatccctgg ataaggattc attcatttcg tttaaagatg tctgggcagc ttttaatttc
      241 tcattctgat tctgaatatc cttatcaaga tagcgaacct gatcctgcca cccggagcca
      301 tattcatgag gcgggttata agtcacaaaa tcatctttat ttgcctctgc ctcttttacc
      361 tttttatcgg cttcctgaac agcagccctt gcaccgggga tcgccttctc tgtcgatgca
      421 atgcgactgt ttaaggtcgc aatattttta tcttcagcat ccagctcagc tttcgcttta
      481 tcatactctc ttttcagccc ctcttccggg tgagcagcgt cccatgcctg ctggcgacgc
      541 ttttcttcct ccagacgctg ttttacctgt gccggagtaa gaacatccgt caccgacaca
      601 tagaccggtt tctgtccgct ctctttcggg aaacgaataa cggcttcacg ggagttacca
      661 ccggccgtaa aaccagccgg acgtgaatca cctttttcag caataatgcc ttttggcggg
      721 gctttcgcgg ccggaacacc tttaggtacg ctcacctgca gagacgggag acccggaatc
      781 gacacactga atacccccgg acgttttgtc ggtttcgcat ccaccacagg aacactcatt
      841 ggccggccgg tgacaaccgc aatatgctgc cgctcgtcct tcacaatatc cgccacacgt
      901 ttagtgacgc tgaccgtcgc ctggtccagc ggcagggagc tgaccggcgt ctccgttacc
      961 gtgtctgccg gcaatgacgt cacgattttt gacatcattt tcggatcatc ttttgctatc
     1021 tcagaaggca gcactccgta aatcgcaatc ccccacagac caaacttaaa cggacctttc
     1081 agggcagcca gcacatcagc aacagcggcc gacaacgcat cgccggaaac ggataaagcc
     1141 agtccttcag cccccggagt ggccaaggca ggcagaccga aggccatcgc ggtggccgaa
     1201 gactgtccgc caccagagct cccgctatga ttgccgctgt taccgccatt accaccgggt
     1261 ttactcccgc cgttaccaaa ctcccccggg ttatagttat gaatatcccc gttaggtgta
     1321 tgcgtcgtac cccagcccgg cccgctgttt ggatccgtac caccacctga tgaagggcca
     1381 cctttacctg atgtaccgtt cacattccca ctggcctgac caccattgtg tcccagacct
     1441 gaattacccg gacctcgtcc gtctccgcca ctcatatact tttcctcttt gacttttaaa
     1501 acaataaact aaaataaaat actgtacata taaccactgg ttttatatac agtataaaaa
     1561 ttacgctgcc ttgtttttca tgtcaagtct gtaaatttgc gtttttgtga aaatgatcaa
     1621 aaaaacagcc actcacacca tgcgcaatcc cctccagatg caacaaaaac cagcacaaac
     1681 ggcgccgttc tccggcctca gtatgtttta ctgaaatcat tatatgagat accagaaagc
     1741 cccctccggg acaggaaaag aaacgggggg tctggttcgg gttgttcggt cactgaacac
     1801 ggtcagaaac tgatgataag atagcctgcg gatatataac tcaatgagaa aaaagaatta
     1861 aaggtaagga gacgctcatg agacgttccg gcagcaaact gtgtcttatc gccatgataa
     1921 cagcgacagc aactctcact gcctgtgctc caaagggcag cgtggaacag catacccggc
     1981 attacgtata tgcttcagat gacggttttg atcccaattt ttccacccag aaagctgaca
     2041 caacacgaat gatggtgcct tttttccggc agttctggga tatgggcgca aaggataaag
     2101 cgaccggaaa atcacggagt gatgtgcagc aacgcattca gcagtttcac agtcaggaat
     2161 ttttaaactc actccaaggc acaacacaat ttgcgggtac cgattaccgc agcaaagacc
     2221 tcacaccgaa aaaatcaagg ctactggctg acaccatttc agctgtttat ctcgatggct
     2281 atgaaggcag acagtaagtg gatttaccat aacgcgtcat tacgcgcacc gctcagacgg
     2341 gctcagggcg tttccggcgg ctacgggata aaacaggcaa caaccccccc ggaaaactgc
     2401 cggaaacgcg cccgataaat tttatcctaa tgcatgccta tgcacgcaac tgcatggcat
     2461 atgttttgac gtaaaatgga tgccgtaagc ccttttttac cgactttctg cttcatcagc
     2521 ctgactgaca cgaccatatt ctttcagacc gccccctgct aaacttcctt catattgccg
     2581 cattaacccg ggaggctccg caatgagcaa cactacacac tacgaaaacg ccaactttct
     2641 tcgggaactg gctgaaagcc tgccccgcat actgccggaa ggtggcccgg acaaagctgc
     2701 gctgttgcag cgactggcta acgaagaact ggcccaggca gagtatgaag atcaggttcg
     2761 cgccaaagtg accgccgccc gtgctgacac gcgtccgggt atgaccacgg aacaactccg
     2821 ccagcgcctg catggccgtt atcaggaact gcgcgatgcc gtatgacgtg gaatggaagc
     2881 agggagccat cgaggatgta acgacgctgt ttgactatat cgcggaaaat tcatccctgt
     2941 gggatgcgca gaacgttacc gaccgggttc tcgctgcggc ggacaaactg gccgacttcc
     3001 cgcgactcta tgaagtggac tcacgctatg gcgaggacgt tcgccggatc agtctgatgg
     3061 gacagcatgt cctctatgat gttgatgacc agaccagaaa agtccgggtt ctggccgtgg
     3121 tcggccagcg ccagaatccc catattgttc tctaataacc ggtgacgggg acgcaattca
     3181 ttgcgtggcc gtcgccggtt ggacaagcac agcgcgtcag cgttttcccc acggccacca
     3241 ccggcgcggt gttccggccg gggtctctgc tgtctccggt ttgtgttcca gcagtctcat
     3301 ggactgcatt tcctgccgta gcccggccac ctcctccctg agtgctttta tctccgcgat
     3361 caacgcgtcg gaggccattt tttcagtctc acccgacagt ctcaactcgt cccgctcgtg
     3421 agtctcatcc tgtcttaact caccgtacac ccggataagc tcgctggtat ccaccacccg
     3481 gccgccatca gcttccgtac ggtatgatac gcggcctttc gccatatccc gatacaggga
     3541 acttcgggct ttacccgtca gttccgtcgc ctgtctcacc gtcacccacg ccattgtctc
     3601 accccgctat ttttgagaca gtatacctga caggcgcaca ccatgcccgg aaggaaagaa
     3661 tcatgacaaa acaggaaaaa acagccctca atatggctaa atttattaag gagcagtcgc
     3721 tgctattgct cgataaactg aatgagctgg atatggatac cccggccgac atgtgcgagc
     3781 ggctacacga ggatgcggaa acactctggc aggtgatgcg ggataagctc ggggaggaat
     3841 aacagcaccg gcatggccgg tgctggcatt tattttttgc cgaacggcca ccaccggcgg
     3901 gcaggtttgt cctccggcag ttcaggtacc ggcacgttaa aatagcggct gttatattcc
     3961 cgcatcagct ccgctttcag cttctcgttc accgcgcttt ccccgtgccg ctcactcacc
     4021 acgtcaatca tcgcgttaat ctgctccggt gagcacttcc cggcatcaac cacctgcaca
     4081 ccgttctcga tggcgaaccg ctccaccttg cgatagaggt aatcacacag cttcattcct
     4141 gtgggtttgt tccgttccca ttgcggattt ttaccagtga aaaagtacgt ggctttttcg
     4201 tcgctgttga gccgctcgtc atacatcccg atggatttca tcatcgccag atgctgggcc
     4261 cggtcgacaa aacagaaaac atacgccccg gtctgccagg cgagcaccac catatcttcc
     4321 agatgctcgc tggtcggcat gatgcagcgc tcgccgttcc ggtcctccgc gtcttcaata
     4381 aataccatgt acagcgccat aatccctcac tccgttgtca taaatttaaa gcacgcaaac
     4441 aaccgttcac gatccagctc tgccgttttg cgggcctcgc cggtctgtgg gttcacgatt
     4501 tcatccaccg acaggattgc ccgctgcacc ctgacctgcg tcgcccggtc cgggcagatg
     4561 taccagattt catcgatgcc gttagctttg cggttgaaca gatacccgga caccacttcc
     4621 tgataccggc gacggctctt gacggtgcgc tccacctcaa acgccaccgt tttaccgtcc
     4681 agctccgcca gggcgtccgg cactttcatg cctttaagac tcagacggtg cagaatgcgc
     4741 cagccggtgg cccctctggc ttccatatca aggcgcaggg attgcacggc cagccggtgc
     4801 ggcagatgtg ctgccgacac ccttgacggc tgaaacggaa taacatccgc cagcggttcg
     4861 tcctcgtcga acgagaacgc cacgccatgc ggcgtcagcc cccacacgct gacctgacgg
     4921 ccgtccaccg gatatttggt ccggaccagc agccctttcg ccaccaggct gtcgaggaag
     4981 cggtagaccg gctgcaccgc cgcaatcccc agccgccgcg caaccagctc cgccgtggaa
     5041 cacagctctt cccgcaacca gcgcagggtc agccgggttt tctccgcgtt ccgcgcctgt
     5101 cgtttcgcgt ggctgacgtt gtacagctcc agcgccatca gtaaatcccc gcaaaatcat
     5161 catccgcttt cggcccgccg ccgtcggccg ggggccggaa ctccgccagg ggatcggttt
     5221 tcgccagcac cgggaaacgc tgcaacggga tttcccggcg ctcaacccgc agcggactgc
     5281 tgaacgccat ccgggccaca cccagcccgg tcatgaccgc gaacccgtcc ggcaggtgtt
     5341 gcagggtgtt cacgtcaaac agcggccgcg cctccttctg gatgaagctg tccccgctga
     5401 tatgctccac gttccccgcc tcccggctgg cacggcggcg ctccacgtcc accctgattt
     5461 ccccggtctg ccccgccgcc cactgcgcgg actccaggct ggccgcccgg taaaaccagc
     5521 ggatcggcgt gttatccagt accgtggttt tcacaaattc agcgggcaga tcctgcccgc
     5581 actgcccgaa atcgcccagc gactggtgcg cgagcaacag attgcagtcc cggctgcgca
     5641 gcgtccccag tgcgttcagt acatacttcg acagcagata tttaatttca tcgagcatca
     5701 cgctgacgtg tggccactcc cggaactcgt cccgcgcaat gatgatttgc gcgcagcggg
     5761 caaacagcat tttttgcaca cggatcaccg cctcgtcgtc catcgagccg ataacgtaca
     5821 ggcagccgcc gccgttgata atccccgcca catcgatgcc actgtccgtc tgcaggacgc
     5881 tcaggtcagc gacgttttcc agcctagtga tcaacccctt cacgtccttt ttcagggcct
     5941 ccggcagcgc gtacgccgcc gccagcacct gctgaatgtt tgccccctgc ggaaactgct
     6001 ccgcaatcag cttcgccgct ttctgctcgc tgatgcggta gtggtccgcc acgtcgccgg
     6061 tctcgcccag gttaagcccg gcaatcagca ggtttttcag cgcgtactgg tcgagatcgc
     6121 ggaacagatt cagctgcgcc ggtttccccg gccgcagatc cagcagggtg aagtccggac
     6181 agtgcgcccg gaagacgtgc ggcgcccatg cgtccccttt ggggtcgaag tacaccaccg
     6241 cgtccccgaa atcgcgtacg cagcgaatga gcgcgttggt ggccatcacg ctcttgccgc
     6301 tcccgggcag gccgaggatc tgaatgttgg tcttgcgcca ggtatcacgc ggaaccagca
     6361 ccggcttgcc ctgctcatcc ttacccagaa acaccgcctg ctcctgccgg gcctgctccg
     6421 aggaaaaatc ggccagcgca ttaaccggta ccggctcccc gaaatgcagg tggcgcacgt
     6481 cggtcatctc tcctgtccgc tggctgctgc gccggctctc ctgattcagt ttcgcgttca
     6541 ccgcctcgtc agcagccgca aaatgaccgt caagcagcag gaacgccagc agccgcgcca
     6601 acacaatccc gacagccagc ccgcccgcgc accaggcaat cccgaacagg ttagccggct
     6661 gcagcaggta ataatctgcg tttgcgtaga ggtccggacg caggacggtt tctccccagc
     6721 tctcgataaa cacggcgaca accagccccc ccagaagggc cagaccggcc gcgccggtca
     6781 gccagtacgc gtagttccag acatgtcgac gtgccctgac catccgcccg ggcgaatcca
     6841 gcgaggccag caccgaaaat ggcgctggcc gtttattatc gcgcttatag cgatcggcat
     6901 actcccgtcg ctccttatga ctcagcccca caaaacgcat ccgtccggcc caaagttcag
     6961 ccagaccgaa aaacaggccg ataactagga aagccccggc cagaccgtaa tactcctggt
     7021 acagccagct gacccacgga taaatctgcc gggccagctc cggaatgtgc cacttccagg
     7081 caagcgaatc cgtattaaac atgttctctc tccttcagac gatggtttgc cggcgtgatg
     7141 tgcagccccc gctgcacaag ccgcggacat gccccaaggc atggcggcgg cggtcacgtc
     7201 cgtggtgatt gcgttcagct ttcaccacgg aggccagcct ctttccgccc catgcggaaa
     7261 aggcgcagcc ccggaggaac aacgagcacg ccccagcgtg tgagaggaaa aggcggcacc
     7321 ccagtgcggt cttttccggt gttccggccc ccgtcagagt tcgccatagc gagcggctga
     7381 ccacccgcaa aatcaggagc agctttgctg cttcgccagg tgcgtccagc accgtggatt
     7441 tttgtgggtg gtcaggcgtg agcctgacgg gggccgggtg aatttctggc gtggccggcg
     7501 tccagccgga cggagccaga aagaggggga gagaccgtgc gtcggtggcg tccagccagc
     7561 gtaagcaggg gatatccccc tgaggtcagc cacgccctcg cggggatgac ctgtatttct
     7621 ccgtaaggag aaaaaagcaa cagagatagg ttaacgtaaa atgttcagcg aaaaaccgat
     7681 atgattcacc tatcctggta atttattatc agggaatata aagacttaat caggggacaa
     7741 tatgccacat cagcgcgtcc ggtgtccgtc ttgtaggtgc cggggaaatt gcgcctcctc
     7801 gctcactcgg tcgctacgct ccggccgtga gactgcggcg ggcgctgcgg acacatgcaa
     7861 agttacccac agattccgtg aataagcagg ggactaacat gtgaggcaaa acggcaaggc
     7921 cacgcaggtg gcgtttttcc ataggctccg ccctcctgac tgagttcaca taaacagacg
     7981 ctttttcggt gcatctgtgg gagccggtgg ctcaaccatg aatcagtcag gagtggcgaa
     8041 acccgacagg acttaaagat catcaccgtt tccgatgaat cgctccctct tgcgctctcc
     8101 tgttccaacc ctgccgtttc ccggatacct gttccgcctt tctcccttgc gggaagtgtg
     8161 gcgctttctc atagctcaca ctctggtatc tcggctcggt gtaggtcgtt cgctccaagc
     8221 tgggctgtaa gcaagaaccc cccgttcagc ccgactgctg cgccttatcc ggtaactgtt
     8281 cacttgagtc caacccggaa aagcacgcaa aacgccactg gcagcagcca ttggtaactg
     8341 ggagttcgca gaggatttgt ttagctaaac acgcggttgc tcttgaagtg tgcgccaaag
     8401 tccggctaca ctggaaggac agatttggtt gctgtgctct gcgaaagcca gttaccacgg
     8461 ttaagcagtt ccccaactga cttaaccttc gatcaaacca cctccccagg tggttttttc
     8521 gtttacaggg caaaagatta cgcgcagaaa aaaaggatct caagaagatc ctttgatctt
     8581 ttctactgaa ccgcgatccc cgtcagttca gaggaggacg atggtgccac cgttccaccc
     8641 tgaacatccc ggatatagtt tgcctgacat gcgaccagaa gaaagcctga aaaaatcaat
     8701 ataaaaagaa aaacaacctt tacctttttc atataccttc cctgtattta aaaaccccgg
     8761 tattcatccc tgaacaccgg aagtctgtat ttcaaatcat ccttgataac ttttgcttac
     8821 cagttaccat cccggtaaac aaaggataca aagtaatcaa atttactaat atcgattaca
     8881 tttttaaagt gtggctgtaa tatcgaaacc catgattttt caacatcaaa ccaaccatta
     8941 ttaatattat cctttaaagg catccccaga ctttcaatga cagaaccatc atcaccgaag
     9001 tcttttgagt attcaccacc tttaaactct tcggttttct tatcaaacca atgaatatgt
     9061 aatttaagcc ccatatttac ctcttaaaga tattttttaa tgtttcgttt tggatccggc
     9121 cctttaacct gcttacccgt ttttggatcg aatgccccga ggtgttcgcc atcactggcg
     9181 cggtaccctt caagctcacc gtgctgggaa tcccattcat aaattttacg ctttttatca
     9241 ccataccatc gggcccgctt accaccacca ccttgtttag gggttttagg ttta
//
