LOCUS       NZ_LR890261             9294 bp    DNA     circular CON 18-JUN-2023
DEFINITION  Klebsiella pneumoniae strain INF310 isolate INF310 plasmid 8,
            complete sequence.
ACCESSION   NZ_LR890261
VERSION     NZ_LR890261.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA3357175
            Assembly: GCF_904863135.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Hawkey,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2020) THE UNIVERSITY OF MELBOURNE, 30 Flemington
            Rd, Australia
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/18/2023 12:05:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,109
            CDSs (total)                      :: 5,980
            Genes (coding)                    :: 5,828
            CDSs (with protein)               :: 5,828
            Genes (RNA)                       :: 129
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 152
            CDSs (without protein)            :: 152
            Pseudo Genes (ambiguous residues) :: 0 of 152
            Pseudo Genes (frameshifted)       :: 73 of 152
            Pseudo Genes (incomplete)         :: 82 of 152
            Pseudo Genes (internal stop)      :: 28 of 152
            Pseudo Genes (multiple problems)  :: 27 of 152
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR890261.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="INF310"
                     /isolate="INF310"
                     /isolation_source="wound swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="8"
                     /geo_loc_name="Australia"
                     /collection_date="2014-02"
     gene            165..1850
                     /locus_tag="JMX51_RS30360"
     CDS             165..1850
                     /locus_tag="JMX51_RS30360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            1860..2117
                     /locus_tag="JMX51_RS30365"
     CDS             1860..2117
                     /locus_tag="JMX51_RS30365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            2202..2351
                     /locus_tag="JMX51_RS30370"
     CDS             2202..2351
                     /locus_tag="JMX51_RS30370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            3832..5796
                     /locus_tag="JMX51_RS30375"
     CDS             3832..5796
                     /locus_tag="JMX51_RS30375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            5796..6527
                     /locus_tag="JMX51_RS30380"
     CDS             5796..6527
                     /locus_tag="JMX51_RS30380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            6534..7064
                     /locus_tag="JMX51_RS30385"
     CDS             6534..7064
                     /locus_tag="JMX51_RS30385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(7092..7271)
                     /locus_tag="JMX51_RS30390"
     CDS             complement(7092..7271)
                     /locus_tag="JMX51_RS30390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            7340..7717
                     /locus_tag="JMX51_RS30395"
     CDS             7340..7717
                     /locus_tag="JMX51_RS30395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(7779..8078)
                     /locus_tag="JMX51_RS30400"
     CDS             complement(7779..8078)
                     /locus_tag="JMX51_RS30400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(8068..8331)
                     /locus_tag="JMX51_RS30405"
     CDS             complement(8068..8331)
                     /locus_tag="JMX51_RS30405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(8637..9056)
                     /locus_tag="JMX51_RS30410"
     CDS             complement(8637..9056)
                     /locus_tag="JMX51_RS30410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     BGC             1..6850
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(2455..3033)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5797..6524
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 ggtgtgagtg gctgtttttt tgatcatttt cacaaaaacg caaatttaca gacttgacat
       61 gaaaaacaag gcagcgtaat ttttatactg tatataaaac cagtggttat atgtacagta
      121 ttttatttta gtttattgtt ttaaaagtca aagaggaaaa gtatatgagt ggcggagacg
      181 gacgaggtcc gggtaattca ggtctgggac acaatggtgg tcaggccagt gggaatgtga
      241 acggtacatc aggtaaaggt ggcccttcat caggtggtgg tacggatcca aacagcgggc
      301 cgggctgggg tacgacgcat acacctaacg gggatattca taactataac ccgggggagt
      361 ttggtaacgg cgggagtaaa cccggtggta atggcggtaa cagcggcaat catagcggga
      421 gctctggtgg cggacagtct tcggccaccg cgatggcctt cggtctgcct gccttggcca
      481 ctccgggggc tgaaggactg gctttatccg tttccggcga tgcgttgtcg gccgctgttg
      541 ctgatgtgct ggctgccctg aaaggtccgt ttaagtttgg tctgtggggg attgcgattt
      601 acggagtgct gccttctgag atagcaaaag atgatccgaa aatgatgtca aaaatcgtga
      661 cgtcattgcc ggcagacacg gtaacggaga cgccggtcag ctccctgccg ctggaccagg
      721 cgacggtcag cgtcactaaa cgtgtggcgg atattgtgaa ggacgagcgg cagcatattg
      781 cggttgtcac cggccggcca atgagtgttc ctgtggtgga tgcgaaaccg acaaaacgtc
      841 cgggggtatt cagtgtgtcg attccgggtc tcccgtctct gcaggtgagc gtacctaaag
      901 gtgttccggc cgcgaaagcc ccgccaaaag gcattattgc tgaaaaaggt gattcacgtc
      961 cggctggttt tacggccggt ggtaactccc gtgaagccgt tattcgtttc ccgaaagaga
     1021 gcggacagaa accggtctat gtgtcggtga cggatgttct tactccggca caggtaaaac
     1081 agcgtctgga ggaagaaaag cgtcgccagc aggcatggga cgctgctcac ccggaagagg
     1141 ggctgaaaag agagtatgat aaagcgaaag ctgagctgga tgctgaagat aaaaatattg
     1201 cgaccttaaa cagtcgcatt gcatcgacag agaaggcgat ccccggtgca agggctgctg
     1261 ttcaggaagc cgataaaaag gtaaaagagg cagaggcaaa taaagatgat tttgtgactt
     1321 ataacccgcc tcatgaatat ggctccgggt ggcaggatca ggttcgctat cttgataagg
     1381 atattcagaa tcagaatgag aaattaaaag ctgcccagac atctttaaac gaaatgaatg
     1441 aatccttatc cagggataag gctgcgcttt ccggggcgat ggagagccgg aaacaaaagg
     1501 agaaaaaagc gaaggatgca gaaaataaat taaatgagga aaagaaaaaa cctcgtaagg
     1561 gaactaaaga ttacggccat gattattttc ctgatcccaa gactgaagat attaaggggt
     1621 tgggagagtt gaaagagggt aaacctaaaa cccctaaaca aggtggtggt ggtaagcggg
     1681 cccgatggta tggtgataaa aagcgtaaaa tttatgaatg ggattcccag cacggtgagc
     1741 ttgaagggta ccgcgccagt gatggcgaac acctcggggc attcgatcca aaaacgggta
     1801 agcaggttaa agggccggat ccaaaacgaa acattaaaaa atatctttaa gaggtaaata
     1861 tggggcttaa attacatatt cattggtttg ataagaaaac cgaagagttt aaaggtggtg
     1921 aatactcaaa agacttcggt gatgatggtt ctgtcattga aagtctgggg atgcctttaa
     1981 aggataatat taataatggt tggtttgatg ttgaaaaatc atgggtttcg atattacagc
     2041 cacactttaa aaatgtaatc gatattagta aatttgatta ctttgtatcc tttgtttacc
     2101 gggatggtaa ctggtaagca aaagttatca aggatgattt gaaatacaga cttccggtgt
     2161 tcagggatga ataccggggt ttttaaatac agggaaggta tatgaaaaag gtaaaggttg
     2221 tttttctttt tatattgatt ttttcaggct ttcttctggt cgcatgtcag gcaaactata
     2281 tccgggatgt tcagggtgga acggtggcac catcgtcctc ctctgaactg acggggatcg
     2341 cggttcagta gaaaagatca aaggatcttc ttgagatcct ttttttctgc gcgtaatctt
     2401 ttgccctgta aacgaaaaaa ccacctgggg aggtggtttg atcgaaggtt aagtcagttg
     2461 gggaactgct taaccgtggt aactggcttt cgcagagcac agcaaccaaa tctgtccttc
     2521 cagtgtagcc ggactttggc gcacacttca agagcaaccg cgtgtttagc taaacaaatc
     2581 ctctgcgaac tcccagttac caatggctgc tgccagtggc gttttgcgtg cttttccggg
     2641 ttggactcaa gtgaacagtt accggataag gcgcagcagt cgggctgaac ggggggttct
     2701 tgcttacagc ccagcttgga gcgaacgacc tacaccgagc cgagatacca gagtgtgagc
     2761 tatgagaaag cgccacactt cccgcaaggg agaaaggcgg aacaggtatc cgggaaacgg
     2821 cagggttgga acaggagagc gcaagaggga gcgattcatc ggaaacggtg atgatcttta
     2881 agtcctgtcg ggtttcgcca ctcctgactg attcatggtt gagccaccgg ctcccacaga
     2941 tgcaccgaaa aagcgtctgt ttatgtgaac tcagtcagga gggcggagcc tatggaaaaa
     3001 cgccacctgc gtggccttgc cgttttgcct cacatgttag tcccctgctt attcacggaa
     3061 tctgtgggta actttgcatg tgtccgcagc gcccgccgca gtctcacggc cggagcgtag
     3121 cgaccgagtg agcgaggagg cgcaatttcc ccggcaccta caagacggac accggacgcg
     3181 ctgatgtggc atattgtccc ctgattaagt ctttatattc cctgataata aattaccagg
     3241 ataggtgaat catatcggtt tttcgctgaa cattttacgt taacctatct ctgttgcttt
     3301 tttctcctta cggagaaata caggtcatcc ccgcgagggc gtggctgacc tcagggggat
     3361 atcccctgct tacgctggct ggacgccacc gacgcacggt ctctccccct ctttctggct
     3421 ccgtccggct ggacgccggc cacgccagaa attcacccgg cccccgtcag gctcacgcct
     3481 gaccacccac aaaaatccac ggtgctggac gcacctggcg aagcagcaaa gctgctcctg
     3541 attttgcggg tggtcagccg ctcgctatgg cgaactctga cgggggccgg aacaccggaa
     3601 aagaccgcac tggggtgccg ccttttcctc tcacacgctg gggcgtgctc gttgttcctc
     3661 cggggctgcg ccttttccgc atggggcgga aagaggctgg cctccgtggt gaaagctgaa
     3721 cgcaatcacc acggacgtga ccgccgccgc catgccttgg ggcatgtccg cggcttgtgc
     3781 agcgggggct gcacatcacg ccggcaaacc atcgtctgaa ggagagagaa catgtttaat
     3841 acggattcgc ttgcctggaa gtggcacatt ccggagctgg cccggcagat ttatccgtgg
     3901 gtcagctggc tgtaccagga gtattacggt ctggccgggg ctttcctagt tatcggcctg
     3961 tttttcggtc tggctgaact ttgggccgga cggatgcgtt ttgtggggct gagtcataag
     4021 gagcgacggg agtatgccga tcgctataag cgcgataata aacggccagc gccattttcg
     4081 gtgctggcct cgctggattc gcccgggcgg atggtcaggg cacgtcgaca tgtctggaac
     4141 tacgcgtact ggctgaccgg cgcggccggt ctggcccttc tgggggggct ggttgtcgcc
     4201 gtgtttatcg agagctgggg agaaaccgtc ctgcgtccgg acctctacgc aaacgcagat
     4261 tattacctgc tgcagccggc taacctgttc gggattgcct ggtgcgcggg cgggctggct
     4321 gtcgggattg tgttggcgcg gctgctggcg ttcctgctgc ttgacggtca ttttgcggct
     4381 gctgacgagg cggtgaacgc gaaactgaat caggagagcc ggcgcagcag ccagcggaca
     4441 ggagagatga ccgacgtgcg ccacctgcat ttcggggagc cggtaccggt taatgcgctg
     4501 gccgattttt cctcggagca ggcccggcag gagcaggcgg tgtttctggg taaggatgag
     4561 cagggcaagc cggtgctggt tccgcgtgat acctggcgca agaccaacat tcagatcctc
     4621 ggcctgcccg ggagcggcaa gagcgtgatg gccaccaacg cgctcattcg ctgcgtacgc
     4681 gatttcgggg acgcggtggt gtacttcgac cccaaagggg acgcatgggc gccgcacgtc
     4741 ttccgggcgc actgtccgga cttcaccctg ctggatctgc ggccggggaa accggcgcag
     4801 ctgaatctgt tccgcgatct cgaccagtac gcgctgaaaa acctgctgat tgccgggctt
     4861 aacctgggcg agaccggcga cgtggcggac cactaccgca tcagcgagca gaaagcggcg
     4921 aagctgattg cggagcagtt tccgcagggg gcaaacattc agcaggtgct ggcggcggcg
     4981 tacgcgctgc cggaggccct gaaaaaggac gtgaaggggt tgatcactag gctggaaaac
     5041 gtcgctgacc tgagcgtcct gcagacggac agtggcatcg atgtggcggg gattatcaac
     5101 ggcggcggct gcctgtacgt tatcggctcg atggacgacg aggcggtgat ccgtgtgcaa
     5161 aaaatgctgt ttgcccgctg cgcgcaaatc atcattgcgc gggacgagtt ccgggagtgg
     5221 ccacacgtca gcgtgatgct cgatgaaatt aaatatctgc tgtcgaagta tgtactgaac
     5281 gcactgggga cgctgcgcag ccgggactgc aatctgttgc tcgcgcacca gtcgctgggc
     5341 gatttcgggc agtgcgggca ggatctgccc gctgaatttg tgaaaaccac ggtactggat
     5401 aacacgccga tccgctggtt ttaccgggcg gccagcctgg agtccgcgca gtgggcggcg
     5461 gggcagaccg gggaaatcag ggtggacgtg gagcgccgcc gtgccagccg ggaggcgggg
     5521 aacgtggagc atatcagcgg ggacagcttc atccagaagg aggcgcggcc gctgtttgac
     5581 gtgaacaccc tgcaacacct gccggacggg ttcgcggtca tgaccgggct gggtgtggcc
     5641 cggatggcgt tcagcagtcc gctgcgggtt gagcgccggg aaatcccgtt gcagcgtttc
     5701 ccggtgctgg cgaaaaccga tcccctggcg gagttccggc ccccggccga cggcggcggg
     5761 ccgaaagcgg atgatgattt tgcggggatt tactgatggc gctggagctg tacaacgtca
     5821 gccacgcgaa acgacaggcg cggaacgcgg agaaaacccg gctgaccctg cgctggttgc
     5881 gggaagagct gtgttccacg gcggagctgg ttgcgcggcg gctggggatt gcggcggtgc
     5941 agccggtcta ccgcttcctc gacagcctgg tggcgaaagg gctgctggtc cggaccaaat
     6001 atccggtgga cggccgtcag gtcagcgtgt gggggctgac gccgcatggc gtggcgttct
     6061 cgttcgacga ggacgaaccg ctggcggatg ttattccgtt tcagccgtca agggtgtcgg
     6121 cagcacatct gccgcaccgg ctggccgtgc aatccctgcg ccttgatatg gaagccagag
     6181 gggccaccgg ctggcgcatt ctgcaccgtc tgagtcttaa aggcatgaaa gtgccggacg
     6241 ccctggcgga gctggacggt aaaacggtgg cgtttgaggt ggagcgcacc gtcaagagcc
     6301 gtcgccggta tcaggaagtg gtgtccgggt atctgttcaa ccgcaaagct aacggcatcg
     6361 atgaaatctg gtacatctgc ccggaccggg cgacgcaggt cagggtgcag cgggcaatcc
     6421 tgtcggtgga tgaaatcgtg aacccacaga ccggcgaggc ccgcaaaacg gcagagctgg
     6481 atcgtgaacg gttgtttgcg tgctttaaat ttatgacaac ggagtgaggg attatggcgc
     6541 tgtacatggt atttattgaa gacgcggagg accggaacgg cgagcgctgc atcatgccga
     6601 ccagcgagca tctggaagat atggtggtgc tcgcctggca gaccggggcg tatgttttct
     6661 gttttgtcga ccgggcccag catctggcga tgatgaaatc catcgggatg tatgacgagc
     6721 ggctcaacag cgacgaaaaa gccacgtact ttttcactgg taaaaatccg caatgggaac
     6781 ggaacaaacc cacaggaatg aagctgtgtg attacctcta tcgcaaggtg gagcggttcg
     6841 ccatcgagaa cggtgtgcag gtggttgatg ccgggaagtg ctcaccggag cagattaacg
     6901 cgatgattga cgtggtgagt gagcggcacg gggaaagcgc ggtgaacgag aagctgaaag
     6961 cggagctgat gcgggaatat aacagccgct attttaacgt gccggtacct gaactgccgg
     7021 aggacaaacc tgcccgccgg tggtggccgt tcggcaaaaa ataaatgcca gcaccggcca
     7081 tgccggtgct gttattcctc cccgagctta tcccgcatca cctgccagag tgtttccgca
     7141 tcctcgtgta gccgctcgca catgtcggcc ggggtatcca tatccagctc attcagttta
     7201 tcgagcaata gcagcgactg ctccttaata aatttagcca tattgagggc tgttttttcc
     7261 tgttttgtca tgattctttc cttccgggca tggtgtgcgc ctgtcaggta tactgtctca
     7321 aaaatagcgg ggtgagacaa tggcgtgggt gacggtgaga caggcgacgg aactgacggg
     7381 taaagcccga agttccctgt atcgggatat ggcgaaaggc cgcgtatcat accgtacgga
     7441 agctgatggc ggccgggtgg tggataccag cgagcttatc cgggtgtacg gtgagttaag
     7501 acaggatgag actcacgagc gggacgagtt gagactgtcg ggtgagactg aaaaaatggc
     7561 ctccgacgcg ttgatcgcgg agataaaagc actcagggag gaggtggccg ggctacggca
     7621 ggaaatgcag tccatgagac tgctggaaca caaaccggag acagcagaga ccccggccgg
     7681 aacaccgcgc cggtggtggc cgtggggaaa acgctgacgc gctgtgcttg tccaaccggc
     7741 gacggccacg caatgaattg cgtccccgtc accggttatt agagaacaat atggggattc
     7801 tggcgctggc cgaccacggc cagaacccgg acttttctgg tctggtcatc aacatcatag
     7861 aggacatgct gtcccatcag actgatccgg cgaacgtcct cgccatagcg tgagtccact
     7921 tcatagagtc gcgggaagtc ggccagtttg tccgccgcag cgagaacccg gtcggtaacg
     7981 ttctgcgcat cccacaggga tgaattttcc gcgatatagt caaacagcgt cgttacatcc
     8041 tcgatggctc cctgcttcca ttccacgtca tacggcatcg cgcagttcct gataacggcc
     8101 atgcaggcgc tggcggagtt gttccgtggt catacccgga cgcgtgtcag cacgggcggc
     8161 ggtcactttg gcgcgaacct gatcttcata ctctgcctgg gccagttctt cgttagccag
     8221 tcgctgcaac agcgcagctt tgtccgggcc accttccggc agtatgcggg gcaggctttc
     8281 agccagttcc cgaagaaagt tggcgttttc gtagtgtgta gtgttgctca ttgcggagcc
     8341 tcccgggtta atgcggcaat atgaaggaag tttagcaggg ggcggtctga aagaatatgg
     8401 tcgtgtcagt caggctgatg aagcagaaag tcggtaaaaa agggcttacg gcatccattt
     8461 tacgtcaaaa catatgccat gcagttgcgt gcataggcat gcattaggat aaaatttatc
     8521 gggcgcgttt ccggcagttt tccggggggg ttgttgcctg ttttatcccg tagccgccgg
     8581 aaacgccctg agcccgtctg agcggtgcgc gtaatgacgc gttatggtaa atccacttac
     8641 tgtctgcctt catagccatc gagataaaca gctgaaatgg tgtcagccag tagccttgat
     8701 tttttcggtg tgaggtcttt gctgcggtaa tcggtacccg caaattgtgt tgtgccttgg
     8761 agtgagttta aaaattcctg actgtgaaac tgctgaatgc gttgctgcac atcactccgt
     8821 gattttccgg tcgctttatc ctttgcgccc atatcccaga actgccggaa aaaaggcacc
     8881 atcattcgtg ttgtgtcagc tttctgggtg gaaaaattgg gatcaaaacc gtcatctgaa
     8941 gcatatacgt aatgccgggt atgctgttcc acgctgccct ttggagcaca ggcagtgaga
     9001 gttgctgtcg ctgttatcat ggcgataaga cacagtttgc tgccggaacg tctcatgagc
     9061 gtctccttac ctttaattct tttttctcat tgagttatat atccgcaggc tatcttatca
     9121 tcagtttctg accgtgttca gtgaccgaac aacccgaacc agaccccccg tttcttttcc
     9181 tgtcccggag ggggctttct ggtatctcat ataatgattt cagtaaaaca tactgaggcc
     9241 ggagaacggc gccgtttgtg ctggtttttg ttgcatctgg aggggattgc gcat
//
