LOCUS       NZ_LR135437            19194 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Enterococcus faecium isolate E8691 plasmid 3.
ACCESSION   NZ_LR135437
VERSION     NZ_LR135437.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA4885878
            Assembly: GCF_900639655.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19194)
  AUTHORS   Arredondo-Alonso,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) UNIVERSITY MEDICAL CENTER UTRECHT,
            Heidelberglaan 100, 3584 CX Utrecht, Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 03:12:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,795
            CDSs (total)                      :: 2,706
            Genes (coding)                    :: 2,634
            CDSs (with protein)               :: 2,634
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 43 of 72
            Pseudo Genes (internal stop)      :: 19 of 72
            Pseudo Genes (multiple problems)  :: 13 of 72
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR135437.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..19194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /isolate="E8691"
                     /db_xref="taxon:1352"
                     /plasmid="3"
     gene            <1..1041
                     /locus_tag="EQB50_RS14285"
     CDS             <1..1041
                     /locus_tag="EQB50_RS14285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="EQB50_RS14290"
     CDS             complement(1657..2337)
                     /locus_tag="EQB50_RS14290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2509..2750
                     /locus_tag="EQB50_RS14295"
                     /pseudo=""
     CDS             2509..2750
                     /locus_tag="EQB50_RS14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /name="peptide-binding protein"
     gene            2799..2882
                     /locus_tag="EQB50_RS14300"
     CDS             2799..2882
                     /locus_tag="EQB50_RS14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            3007..3744
                     /gene="erm(B)"
                     /locus_tag="EQB50_RS14305"
     ARG             3008..3741
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <3914..4174
                     /locus_tag="EQB50_RS14315"
                     /pseudo=""
     CDS             <3914..4174
                     /locus_tag="EQB50_RS14315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            4337..>5002
                     /locus_tag="EQB50_RS14320"
                     /pseudo=""
     CDS             4337..>5002
                     /locus_tag="EQB50_RS14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            5038..5283
                     /locus_tag="EQB50_RS14325"
     CDS             5038..5283
                     /locus_tag="EQB50_RS14325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            5386..6255
                     /locus_tag="EQB50_RS14330"
     CDS             5386..6255
                     /locus_tag="EQB50_RS14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            6236..6970
                     /locus_tag="EQB50_RS14335"
     CDS             6236..6970
                     /locus_tag="EQB50_RS14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            7003..7911
                     /locus_tag="EQB50_RS14340"
     CDS             7003..7911
                     /locus_tag="EQB50_RS14340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="WP_001255866.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDI
                     TYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLL
                     PLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPY
                     VIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLW
                     EKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKY
                     TGKTGCLDSTYAADIEERREQ"
                     /name="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
     gene            7908..8450
                     /gene="sat4"
                     /locus_tag="EQB50_RS14345"
     ARG             7909..8447
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8543..9337
                     /gene="aph(3')-IIIa"
                     /locus_tag="EQB50_RS14350"
     ARG             8544..9334
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9613..>9726
                     /locus_tag="EQB50_RS14360"
                     /pseudo=""
     CDS             9613..>9726
                     /locus_tag="EQB50_RS14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(9768..10448)
                     /locus_tag="EQB50_RS14365"
     CDS             complement(9768..10448)
                     /locus_tag="EQB50_RS14365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            10510..11205
                     /locus_tag="EQB50_RS14370"
     CDS             10510..11205
                     /locus_tag="EQB50_RS14370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002326819.1"
                     /translation="MQQNPTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFIQRVEE
                     QLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERSELVENF
                     VSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLTCGTESIV
                     LMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPY
                     QRFERKKRQ"
                     /name="hypothetical protein"
     gene            complement(11252..11488)
                     /locus_tag="EQB50_RS15150"
     CDS             complement(11252..11488)
                     /locus_tag="EQB50_RS15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_306297428.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISFF
                     LLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
                     /name="hypothetical protein"
     gene            11586..11765
                     /locus_tag="EQB50_RS14380"
     CDS             11586..11765
                     /locus_tag="EQB50_RS14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001120991.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            11896..12165
                     /locus_tag="EQB50_RS14385"
     CDS             11896..12165
                     /locus_tag="EQB50_RS14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_000388479.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            12158..12415
                     /locus_tag="EQB50_RS14390"
     CDS             12158..12415
                     /locus_tag="EQB50_RS14390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_000588503.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            12874..13878
                     /locus_tag="EQB50_RS14395"
     CDS             12874..13878
                     /locus_tag="EQB50_RS14395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000455809.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINVF
                     FYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACEI
                     GVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRNKL
                     VHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQITL
                     SKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
                     /name="hypothetical protein"
     gene            complement(14043..14657)
                     /locus_tag="EQB50_RS14400"
     CDS             complement(14043..14657)
                     /locus_tag="EQB50_RS14400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001261742.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            15107..16432
                     /locus_tag="EQB50_RS14405"
     CDS             15107..16432
                     /locus_tag="EQB50_RS14405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_000969590.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            16425..16775
                     /locus_tag="EQB50_RS14410"
     CDS             16425..16775
                     /locus_tag="EQB50_RS14410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            16772..16951
                     /locus_tag="EQB50_RS14415"
     CDS             16772..16951
                     /locus_tag="EQB50_RS14415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            17087..17377
                     /locus_tag="EQB50_RS14420"
     CDS             17087..17377
                     /locus_tag="EQB50_RS14420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            17745..18533
                     /locus_tag="EQB50_RS14425"
     CDS             17745..18533
                     /locus_tag="EQB50_RS14425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            18520..18846
                     /locus_tag="EQB50_RS14430"
     CDS             18520..18846
                     /locus_tag="EQB50_RS14430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             7004..7908
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             3008..3744
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     ARG             7909..8450
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             7004..7911
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="109.42"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 gaatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcatcga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cgcttttata tattaatcac aaatcactta tcacaaatca caagtgattt
     2461 gtgattgttg atgataaaat aagaataaga agaaatagaa agaagtgagt gattgtggga
     2521 aatttaggcg cacaaaaaga aaaacgaaat gatacaccaa tcagtgcaaa aaaagatata
     2581 atgggagata agacggttcg tgttcgtgct gacttgcacc atatcataaa aatcgaaaca
     2641 gcaaagaatg gcggaaacgt aaaagaagtt atggaaataa gacttagaag caaacttaag
     2701 agtgtgttga tagtgcagta tcttaaaatt ttgtgtataa taggaattga agttaaatta
     2761 gatgctaaaa atttgtaatt aagaaggagg gattcgtcat gttggtattc caaatgcgta
     2821 atgtagataa aacatctact gttttgaaac agactaaaaa cagtgattac gcagataaat
     2881 aaatacgtta gattaattcc taccagtgac taatcttatg actttttaaa cagataacta
     2941 aaattacaaa caaatcgttt aacttctgta tttatttaca gatgtaatca cttcaggagt
     3001 gattacatga acaaaaatat aaaatattct caaaactttt taacgagtga aaaagtactc
     3061 aaccaaataa taaaacaatt gaatttaaaa gaaaccgata ccgtttacga aattggaaca
     3121 ggtaaagggc atttaacgac gaaactggct aaaataagta aacaggtaac gtctattgaa
     3181 ttagacagtc atctattcaa cttatcgtca gaaaaattaa aactgaacat tcgtgtcact
     3241 ttaattcacc aagatattct acagtttcaa ttccctaaca aacagaggta taaaattgtt
     3301 gggagtattc cttaccattt aagcacacaa attattaaaa aagtggtttt tgaaagccat
     3361 gcgtctgaca tctatctgat tgttgaagaa ggattctaca agcgtacctt ggatattcac
     3421 cgaacactag ggttgctctt gcacactcaa gtctcgattc agcaattgct taagctgcca
     3481 gcggaatgct ttcatcctaa accaaaagta aacagtgtct taataaaact tacccgccat
     3541 accacagatg ttccagataa atattggaag ctatatacgt actttgtttc aaaatgggtc
     3601 aatcgagaat atcgtcaact gtttactaaa aatcagtttc atcaagcaat gaaacacgcc
     3661 aaagtaaaca atttaagtac cgttacttat gagcaagtat tgtctatttt taatagttat
     3721 ctattattta acgggaggaa ataattctat gagtcgcttt tttaaatttg gaaagttaca
     3781 cgttactaaa gggaatggag ataaattatt agatatacta ctgacagctt ccaagaagct
     3841 aaagaggtcc ctagcgccta cggggaattt gtatcgataa ggggtacaaa ttcccactaa
     3901 gcgctcggga ccccttgtag gaaaatgtcc taagtgtggc aacaatattg tattaaaaaa
     3961 atcgttttat ggttgttcaa attatcctga atgtaagttt actttagctg aacattttag
     4021 aaagaaaaaa ctaaccaaaa cgaatgtaaa agaattactg gagggaaaag aaaccctggt
     4081 aaaaggaatc aaaaacaaag agaaaaagcc ctacaatgcc gttgtaaaaa ttggggaaaa
     4141 gggatatatt gattttatct ctttttcaaa ataaacatgg ggctgaccca aaagtagctc
     4201 ctatatgaaa aatagaggtc tttccattta gatagtagtg gaaagacctc tatttatctt
     4261 ttgaaagtga atacaaaaat aaagcacact ctgctataat ataggtgatt aatccatttg
     4321 agagaggtgc tttatcatgt atcaaaatta taccataaac caactttgtt tgcctataga
     4381 tcttgaaatt aaattagaag aaaatgattt tgctcatgcc attgtgcagt ttgttgactc
     4441 tattcccgat gaagtctttc ttccttatta tcaatctatg ggtagacccc aatatcatcc
     4501 tcgtatgcta ctttccatta ttctttgtgc ctatattcaa ggggtttatt cgggccgcca
     4561 aatacaaaat atgctgatag atagtattcg gatgcgctac ttatctcaag agcaattccc
     4621 taactttcgt actattaatc gttttcgcgt tcatccgatt atgaacgata ttctagatca
     4681 ttcatttgtt caatttcgtg agctactggt tcaaagtggc ttaatcagtg gcagtgctct
     4741 atacattgat ggtacaaaaa ttgaagcgga tgcgaataaa tactctttcg tttggaaaaa
     4801 aagtatttta aagtataagg atagccttga tcaaaaagcc cttgaaaact accaacaaat
     4861 ggtggaaaca aaaatcttac ctgagttaat agatgattta aaggatgaac tttctataga
     4921 agagattgaa aggattcgtc aatctttgga agaaaaggaa aatcaattaa ttgaagcgat
     4981 tgaccaaacc gaaacagtag aagggggctg acccattatt aataaggagt ggacaacatg
     5041 attgatgtaa atgagctatt ggaagaagct attagagaaa ctgaaaatct aaatgatggc
     5101 gaagtttttc ttgttaaaga tttattcaag ggatatgtgg ggaataggat acccagaaag
     5161 gatcgacttc tgcttggaac gttattttta aaccatgtta gcaaaatgaa tggtaattta
     5221 aaggctattg aaaagacttc atctaatcag cagaggtata aaaagacaat tgataagttt
     5281 taactatctt ttgtgaaatt aaaaaaatta taaatatgtt gagtagaagc aaaagatttg
     5341 gcttggaatt tttacagcag tgaatcgata aaaggagcat gcttgatggt agataatatt
     5401 attaaatcag tagcagagaa attatcctct ctgtcttata tagaaggtat tgttttaggt
     5461 ggttcacgtg caaggggcac ccatacagag gattcggata tagatatcgg catctattac
     5521 aattcagaat catttgacat aaatactatt aatcaattcg ctacaaagct ggatgatgag
     5581 catagaaata accttgttgt acctcccgga gcatggggtg attggattaa tggcggcgga
     5641 tggttagtca taaacgggta tcatgtggat ttaattttac gtgatattaa acgtgtggaa
     5701 caaataatga aagatacaga gcacggaatt gttactgcca attatcagac tgggcatccc
     5761 catggttata ttagtgcaat gtatcgagga gaattagcga ttagcaaaat actatatgct
     5821 aagaatgaaa gcttatgcga attaaaaaaa caggcagaaa cttatcccaa tgctttgcag
     5881 aaaagtttag ttaacttttt tatgtttgaa gcagggttct ctttaatgtt tgtaaaagca
     5941 aattcgggaa cagacgataa atattatatt gcgggtcatg tttttcgtat agtttcatgt
     6001 ttaaatcaag tgttatttgc atgtaataat gcttattgta tcaacgaaaa gaaagctata
     6061 aaactgcttg aaacttttga acataaacct gaaaaatata ccgagaaggt aaatcatatt
     6121 tttgaagtac tcggtatctc actttttgaa tgctacgaca tgaccgagaa gctttataat
     6181 gaagtgaatg aaattgtatc ggagataaat aactttttaa acgaggagag ttcagatgaa
     6241 agaaaacaaa tatgatgata atatattttt tcaaaaatac agtcaaatga gtcgctcgca
     6301 gaaaggactg gctggtgcgg gagaatggga gactttgaaa aagatgctac ctgattttaa
     6361 gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg cactgtatat atgcgatgga
     6421 aaacggtgct tcctctgtag taggtgttga tatttctcat aaaatgctcg aagtagcaaa
     6481 aggaaaaacc cattttccac agattgaata tgaatgctgt gccatagaag atgtggattt
     6541 cccagaggag agctttgatg taatactaag ttcgcttgcg tttcattatg tagcagacta
     6601 tgagaattta ataaaaaaga tatataggat gctgaaggct ggtggcaatt tagtttttac
     6661 agttgaacat cctgttttta ctgctcatgg aacacaagac tggtattata acgaaaaagg
     6721 agaaatactg catttcccgg tggacaatta ttattatgag ggcaaacgga cagctatgtt
     6781 tttggaagaa aaggttacaa aatatcatag aacactgacc acatatctaa atacactgct
     6841 ttcaaatagt tttataataa atcagattgt ggagccacag ccgccagaga acatgatgga
     6901 tattccgggg atggcggatg aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa
     6961 gaagatgtaa taatatagaa aaaataaacg aggagtatgt aaatgagatc agaaaaagaa
     7021 atgatggatt tagtactttc tttagcagaa caggatgaac gtattcgaat tgtgaccctt
     7081 gaggggtcac gcgcaaatat taatatacct aaagatgaat ttcaggatta tgatattaca
     7141 tattttgtaa gtgatataga accgtttata tctaatgatg actggcttaa tcaatttggg
     7201 aatataataa tgatgcaaaa gccggaggat atggaattat tcccacctga agaaaaggga
     7261 ttttcctatc ttatgctatt tgatgattac aataaaattg atcttacctt attgcccttg
     7321 gaagagttag ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat
     7381 tgtagaatta aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc
     7441 gcaagggagt atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa
     7501 ggattgtgcc gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat
     7561 gagctgctga gaatgatatc atggaaggtc ggcatcgaaa caggctttaa attaagtgta
     7621 ggcaagaact ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg
     7681 tccacctacc ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa
     7741 ttgttcaggg cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat
     7801 gataggaata taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc
     7861 tgcctggata gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa
     7921 tgaaagcagg gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta
     7981 agattatacc gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc
     8041 catatttaaa aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg
     8101 aatatattga caatactgat aagataatat atctttacta ccaagacgat aaatgcgtcg
     8161 gaaaagttaa actgcgaaaa aattggaacc ggtacgctta tatagaagat atcgccgtat
     8221 gtaaggattt cagggggcaa ggcataggca gcgcgcttat caatatatct atagaatggg
     8281 caaagcataa aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt
     8341 gtaaattcta tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca
     8401 actttgaaaa caactttgaa aaagctgttt tctggtattt aaggttttag aatgcaagga
     8461 acagtgaatt ggagttcgtc ttgttataat tagcttcttg gggtatcttt aaatactgta
     8521 gaaaagagga aggaaataat aaatggctaa aatgagaata tcaccggaat tgaaaaaact
     8581 gatcgaaaaa taccgctgcg taaaagatac ggaaggaatg tctcctgcta aggtatataa
     8641 gctggtggga gaaaatgaaa acctatattt aaaaatgacg gacagccggt ataaagggac
     8701 cacctatgat gtggaacggg aaaaggacat gatgctatgg ctggaaggaa agctgcctgt
     8761 tccaaaggtc ctgcactttg aacggcatga tggctggagc aatctgctca tgagtgaggc
     8821 cgatggcgtc ctttgctcgg aagagtatga agatgaacaa agccctgaaa agattatcga
     8881 gctgtatgcg gagtgcatca ggctctttca ctccatcgac atatcggatt gtccctatac
     8941 gaatagctta gacagccgct tagccgaatt ggattactta ctgaataacg atctggccga
     9001 tgtggattgc gaaaactggg aagaagacac tccatttaaa gatccgcgcg agctgtatga
     9061 ttttttaaag acggaaaagc ccgaagagga acttgtcttt tcccacggcg acctgggaga
     9121 cagcaacatc tttgtgaaag atggcaaagt aagtggcttt attgatcttg ggagaagcgg
     9181 cagggcggac aagtggtatg acattgcctt ctgcgtccgg tcgatcaggg aggatatcgg
     9241 ggaagaacag tatgtcgagc tattttttga cttactgggg atcaagcctg attgggagaa
     9301 aataaaatat tatattttac tggatgaatt gttttagtac ctagatttag atgtctaaaa
     9361 agctttaact acaagctttt tagacatcta atcttttctg aagtacatcc gcaactgtcc
     9421 atactctgat gttttatatc ttttctaaaa gttcgctaga tagagttcta tattagagat
     9481 gtaaagagtt ttggtgaaga ggtttgtgag tatggctttt ataaccaggg tgcaatgaga
     9541 agcactaaca gcagctagct taagaacgca taggatatac tttttatgga agtcacagag
     9601 gaggaataaa atttgaacag gattaacaga gtaacctcta ttcttattca gctgcaatca
     9661 aaaaaaataa ttcctgccaa agaaattgca cagcgattta atataagctt aagggttctg
     9721 ttgcaaagtt ttaaataaag aataaaatcc cttacggtat ctatgattta agctgggatt
     9781 cccaataata ccttgatttc agtacagacc gaaaacccga agagagtgcc ttcttttcgg
     9841 gttttcttat ataatcctcg aatggcttcc atgcctttaa tcgtggtaga ggcagtgcgt
     9901 aaacttcgat agaatttatt gcgtctcttt actggacgat ggtcttgttc aatcaaatta
     9961 ttcaggtatt taatggtacg atgttctgtc ccttgataaa agccgtattc ttttagtttc
    10021 ttaaaggcac ttgtaataga gggggcttta tctgtgacta caaccttcgg ttcatcaaac
    10081 tgcttcacta accgcttaag aaaagcatag gctgcttgtg tgtcccgttt tttacgtaac
    10141 caaatatcca aggttaaacc atctgcatcg atggctcgat acaaataatg ccattttcct
    10201 ttaattttga tgtacgtttc atccattttc catgaataaa aggatttttt atttttcttt
    10261 ttccaaattt gatagagtag tttgccatat tcttgcaccc aacgataaat cgtcgtatga
    10321 gaaacgttaa tgccacgatc atataagatt tcttgaactt cacgatagct aaggttataa
    10381 cgaagatagt agcccacggc tacaataatc acatcctgct gaaattgctt tcctttaaaa
    10441 tgattcatcg tcattcctcc tgctatcttt ttctattatt ctaccttatt tgatagtaga
    10501 tttaaaactt tgcaacagaa cccaacggaa gatgtgtcac actttttaac aaacaaagaa
    10561 catttgaatg aagtaatcag acggattcaa aaagacttta gttgtatgga agaaatgaag
    10621 tactttattc aaagagtcga agaacaattg tatttggaaa gtgaaacgag tcaaacgaag
    10681 gtcacagtca gccataatcg tttagacgtg tataaacgtc gtcctgaaac ggtaaaaaaa
    10741 ggaacggagc ttctacgact agaaacagaa aaatacatca tgaatgttta cctagaaagg
    10801 agtgagctgg tcgaaaactt tgtcagctac acgatttgca ggaaacacta ttactcagaa
    10861 tcagaatatt attcaatttt tgagagcatg gaattaatgg aagaagaaat ggaagagcta
    10921 aacagcaaag atgcgacgat agacgattat taccttgtat ttactagatt tttgacgtgt
    10981 ggaacggaat ctatcgtgtt aatgggaatg gattatgaac tcgctgtacc cgaagcattt
    11041 ttgagggaat atgtagaaga agtagataac ccaggcgacg actggtacac gactttaact
    11101 gattttttag acacctatac ttacgacgat acagaagaaa tccaaaatga acttgaccgt
    11161 aaacgaatgc catatcaacg atttgaaagg aaaaaaaggc aataatcatt tataccgaaa
    11221 agtgagaatg tgtgaaataa ggacaaaaaa cctagtaact aagggaatgg ttcttatttc
    11281 gcaccaatcg ctccaaccgc ccccgccgct taggtggtgc gaaataagcg ggcaacaccc
    11341 gataacctaa gagaaagaag gagatccata tgaataaaat cattcctcta ttgttagtcc
    11401 tatttgttgg cgaaatactt atgcgccatg ctgcagctgt gcatttaaac ttcgtagtat
    11461 ttttggcaat actggtattt tgtttgatct tttggcgctt tgtattagcc cttgtgagtc
    11521 tactattcaa gatgattgca gccatatttt tcatagggtt atttcgatga aaggagagag
    11581 tactaatgcc aattgcaata ggaaataaac ggttacccgt tacgttggat gaaaagagac
    11641 aaaaagaatt gcagcaacta aagcagaagt acggcaaaag tgaatccagg attatgtgta
    11701 ttgcgttaga tttattgatt gcccaagaaa aagcaggatt tgaggtacca gcactcaaaa
    11761 agtgacgtca ctttttatcc taaaaactaa aagtgatagc acttttaatt ataagaagtt
    11821 agaatattaa tcatttgctt aattgtacaa tataatgtac aattgtttta tagaaataaa
    11881 taaggggtga aaggaatgga agcagtagct tattcaaatt tccgccaaaa tttacgtagt
    11941 tatatgaaac aagttaatga ggatgctgaa acacttattg taacaagtaa agatgtagaa
    12001 gatacagttg ttgtattatc aaaaagagat tatgattcta tgcaagaaac gttgagaaca
    12061 ctttctaata attacgtcat ggaaaaaatt cgtcgaggag atgaacaatt ctccaaaggt
    12121 gcatttaaaa cacatgactt aatcgaggtt gaatctgatg attaaggctt ggtctgatga
    12181 tgcttgggat gattatcttt attggcatga gcaaggaaac aaaagcaata taaaaaagat
    12241 taacaagtta ataaaagata tcgatcgttc cccctttgct ggattaggaa aacctgagcc
    12301 attaaagcat gatttatctg gaaaatggtc cagaagaatt acagatgaac atagactgat
    12361 atatagagtt gaaaatgaaa cgatatttat ttattctgca aaagatcact attaaccaat
    12421 cggaagtaag gaaagggtca gaaacttaaa agtttttgat ccttatttta tttaccctag
    12481 tcatttaaaa agctaatata gcttagtgtt gattgttatt aatgaatgtg tttgttacgc
    12541 gtattacgga tataaggtta gtaaaatcat ttctaaagtt gaggaaaagt aaatataaat
    12601 ggcttaaatt tcaacaattt gaagttgaat agatatgtta taatactatt gtagtgtggg
    12661 atgttagtta ctaaaggatg acgcttatat atatgactga atagaataag caataggttt
    12721 aataatctat tttaaatttt ttgtactagt tttagttaat tagcaaaaac aacaaaaata
    12781 aacttctcat agaatttagc taaaaattaa tgatttattt acatattaaa tttggataca
    12841 gttaagtaat ttttatatat tggaggagaa gtaatggaat ataaatttaa cttgaatttg
    12901 aaagaagtac tccccactca gggaacaata aacataaatg gtcaagataa tgatgacgat
    12961 atagtaataa aaaaaataga atttattgat tctgatataa atgttttttt ttattctaaa
    13021 gaaaaattag ctgattttag caatattgct gaaatgattg aacgtttaaa agattttatg
    13081 atcagtgttt gggatgtagc gatgcttgct gacgaatcaa attatacttc gagcatatac
    13141 agattagaag atagtaattg gatagaaatt tcattagagt taaagacact tcctaattcc
    13201 gttaactata taattagaga tataacttct gaagctcaac aattagttaa ttacatgcat
    13261 ggacacgaaa gtatcccctt ttctcttata ctccttaaaa gaagtaaaaa tatatcaaat
    13321 actagagata ggtttatttc gataattaca gcctgtgaaa taggggtaaa ggaattttat
    13381 caacaagaga aacctgattt aactctaata tttgagaatt tacaatctcc ccctgtagac
    13441 aaattattag ggagcatgtt taaagggtac tttaatattg agtttccgaa agaaataaga
    13501 aaggaaatta aaaatttcat agaaaaacgt aataaattgg ttcattctcc tcaaggaagt
    13561 aaaccaacta tagaagaatg ttttgaatgt tatatggcag tgctaaaaac atttaatttt
    13621 ttttataaaa ttaatgatag ctttatgtat agagattttt atgaagaatc tatagaattg
    13681 actccaacgg aaccaaataa atctcaaatc actttgtcaa aggagctaga gagaaaagta
    13741 gagtctcaag aactagctat aggaattagt ataaccaatg tgtcgacata caaagaatta
    13801 tacgaagcta aatcacaaga taataaggat tttgtagaaa atatagataa ggaaccaaca
    13861 aatacagtag gggattaacg taaataagtg aagattatat taacagactc tttatttagt
    13921 taagtaaaaa atggtttgtt ggaattttat gctttatctg ttctgagtaa gacttaattt
    13981 tatagatagt aattatatgt aggaaattaa agatgagaag ataataaaag cagcatgatc
    14041 aactatttgt cattgaccat gctgtctttt tttattctat acacggtttg tctcgtaaca
    14101 ttgtagtctt tagcaatctt agcaatcgca acaccatttt taagatcttc aacgatgctt
    14161 ttgtaaacaa ggcgacgttg gggatctttt gcgtctgcac tgtataattt gggccgccct
    14221 ttgtagacgc cgtttgcttt tgcgatctta attccttgtg cctggcgacg tttcgattca
    14281 gtccgttctt gttcagcgat catggccaaa atttggatga tcagatcctt aatgaattta
    14341 tccaggagag gattgccaat tgcttcagcc atgatcggta aactagtaat gatcagcttc
    14401 acatttttct tcttcaagta attgactgaa gcgatgatct cgtcataatt tcttccaagt
    14461 cgatcaatag cttccacaat aaaaatatct tgatctcgga cgtaatctaa tgcttcttgg
    14521 aaaacaggtc gatgagtaat cgttgcgcca gattgtttct cgatgaaaat tctctctgca
    14581 ccgaattttt tcatttcttc aatctggcgt tgttcatttt gatcgatcga tgagacacgt
    14641 atgtatgcaa ctctcaaaac ttttacctac tttctgcaac tatttaaaat acaccctaat
    14701 catacacgag gaagccatat ttttcaatgt tataccagtg tctatttagg gtaaacctta
    14761 tatagacaaa aactaatgat ggaggaaata gtatgagaat tttttgtaag tgtctactga
    14821 taacttattc tcaaatgttg taaggatttt attcatttgt taatattaaa gaacggaact
    14881 ccaaaaaagt ccgtactcta atttgcagtc tctcactctt ttagagtgag agtttttatt
    14941 agattttcaa attaattagt aaagtgatag aataaattga tcatacaaat caaaagaaga
    15001 agcagggtga tagcatacct atgcttcttt ttttatgtat ttagctattt cttctttaca
    15061 atatcgaaca tatgtttgta taatgtgaaa gaatggagtg ttatttatga tggattattc
    15121 aaaagagcca gtaaatgatt actttttaat cgatatgaaa agcttttacg caagtgtcga
    15181 atgtatagaa agaaatttag atccattaac aacagaactt gttgttatga gtcgagctga
    15241 taatactggt tcaggattga tattagcttc ttctcctgaa gcaaaaaagc ggtatggtat
    15301 tacaaatgtg agtagaccac gtgacttacc acaaccattt cctaaaacac tacacgttgt
    15361 tccaccacgt atgaacctat atatcaagcg aaatatgcag gtaaataata ttttcagaag
    15421 atatgtggct gatgaagatc tactgattta ctcgatcgat gaatcaatct taaaagtgac
    15481 ccgatcactg aatcttttta cgactgaagg aacacgaagt caacggagaa agaagctggc
    15541 tcaaatgatc caggagaata ttaaagaaga gctaggattg attgctacag taggtgtcgg
    15601 agataatccc cttttggcta aactagcctt agacaacgaa gcaaagcata atgaaggatt
    15661 tgttgcggaa tggacgtacg aaaacgttcc tgaaaaagta tggaatattc ctgaaatgac
    15721 ggacttttgg ggaattggct ctcgaatgaa aaaaagactc aatcagatgg ggattatgag
    15781 cattagagat cttgctaact ggaatcctta tacgattaag aatagactag gtgtgattgg
    15841 cttacagctg tacttccatg ctaatgggat cgatcgaaca gatatagcaa tcccaccaga
    15901 accgacaaag gaaaaatcat atggaaattc acaagtgtta ccacgagatt atactagaag
    15961 aaatgaaatc gagctggtgg taaaagaaat ggcggaacaa gtagcgatac gcattaggca
    16021 gcataactgt aaaacaggtt gtgtccattt acacattggc acgtcgatct tagaaacgag
    16081 accagggttt tcacaccaga tgaagatccc tatcacagat aatacaaagg aattgcagaa
    16141 ttattgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc atgttggaat
    16201 aacctatagc aagcttgtgt acaccgattc gcttcagctg gatttattta gtgatccaca
    16261 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
    16321 ttttacgtcg attgtacatg cttcttcaat gttagaaggc gctagaagca ttactagaag
    16381 cacacttgtt ggtggtcatg cgggcggaaa tgggggaatt aaaaatgatt gattacaatg
    16441 atcgtggacg tttaaagtgg gcagggtttt atttatctga tcatactgaa gaaattgatg
    16501 ccgacaatga acaacgaacc agtcaaaatt tagcaaaaga acaaatgacg actgaagaga
    16561 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatctatt caaaaagaag
    16621 aacgaaacgc tgaaggatac tatccagaag atatcattgg caagatctta ggtagtgatg
    16681 agctggggat ctacgttgga aaagacaaaa ttcactacga cgaaatacgt catatcgaat
    16741 tttaccagga taataaatgg agtcgattag aatgaacatt atccagcaat atgagctaaa
    16801 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccaac gtttgataaa
    16861 tgaggttggt gttgagcgct tctctttcta tgtagaagct gcagcaggtt atcataattt
    16921 taggttttat atcttcccgt tatatatata aggtatttta cggattctat agagttatct
    16981 ctatgaatcc ttttttgttt ttacaaatag gagtagatac tagaataatg cgtgtgttaa
    17041 actattattg caaacgcaat aataaaagaa agtaggctta cgcaccatgt ctatcaatac
    17101 atttgtttac tcgcacccga tcaatgttta cattatcaag aatttaggaa tcactgtaga
    17161 acaattttgt gagttatatg cctacccaca aggaacggtt gcaagctgga taacccgaca
    17221 acgtagaata aaatcattac ctgcttcatt cgtttatgat ttaagcctgg cctctagttt
    17281 aaacatgtct gatgtttatg aaaagctcct gtctttagaa aaagaatatg attccttcaa
    17341 gattaaacat gataaaaaaa taaaaaaaca tatataatat caatcacaat tgtataatat
    17401 tacgatatct taatatcatg atatcgtaat attgtttttt tctaagaaaa tgcactataa
    17461 gaagggaatt attagtaaca atatagacag tttagtaatg tttaaattat tctagttgct
    17521 gctcgcaaaa catatttctt atcattaata aaaaatttta aagtaataaa aagtgattat
    17581 tttaatttcg aataacatat gaataatctt tatatccgaa ccgatatata tctttaaaac
    17641 aaaataatca cacaatatta caatataatg catatacgat attgcaatat cacaatatta
    17701 tgatataatt atattataat ataagatgaa tgggggatat tttaatggca agaatattgt
    17761 cagtagccaa tcaaaaaggt ggagtttcta aaactacgac tagcgttaat ttagcagcat
    17821 gtttgaaatt tgtttacggt aaaaatgtac ttttagtgga cattgatcct cagggaaatg
    17881 ctacagataa tgtaggtttc gatatagatg gaacaaacca acctacaatt tatgaagtat
    17941 taaaagggga ggctgacatt acagatgcta ttctggacta taaaggaatt gatgttttgc
    18001 cagccgacat agccctttct tctgcagaga gggaatttac tcaagtagga agtgaacaca
    18061 ggcttaaaag agtacttcaa ccaatcaagg acaactatga ttatattata attgattgtc
    18121 caccaagttt aggaatgctt acagtcaacg catttactgt ttctgatgaa attatcattc
    18181 cagttgaagc tgcgtatttc tcattaaaag gactaataaa gttaagtgaa actattgaaa
    18241 cggtaaaaga atatacgaac gacaagcttg aagtacgagg agttctattt actaagtata
    18301 ataagcgtta taacatttct aaagaaatga cgtctgcagc aaccgaaatt tctagagtca
    18361 ttggtgcaaa aattttcaaa acttatattc gtaggacaat aaccgttgac gaagcgcaag
    18421 ctgctggatc agatctaatc aattttaata aaccctcaac agctgaagat gactataaag
    18481 catttacaga agaatattta aaagaagttg gtgattttga tggcagaaga taatcgcagt
    18541 caagctgcag taagtagatt actaggaaat aaaaataaaa agaattttaa atcaaaagaa
    18601 gtagaagaaa tcgaattaac caagaaaaat ataagtaaag tcataaaaga tcaaggaagt
    18661 agtgtaagaa cagcagatag cattcgtata aatccaattc taatgtcagc actcaaatat
    18721 tggacgacta ttgctgaatc agacaaaagt aaaccagacg ttatagaaga tgcgctatta
    18781 aagtccatac ctgaagaata cttgattgaa ggatataaac tagcaaagaa acaaaataaa
    18841 atttaattta cattcaatat cacgatatca taatatcgtg atattttttt tataaaaatc
    18901 agtagtatca aagctgataa gtcgcttatc ttcatattgt aatattacga tatcgtgata
    18961 taatattatt gtaatatcgt gatatagtta ctatgagctt aaaccttgaa atagagcggt
    19021 ttgctttaat ttatttttta aggtaaacta aaaaaagata aaaaaagact actgctttaa
    19081 caaagtttgg cgacttatca gcagtagaaa aatatatagt ggatagatat atttgtttaa
    19141 ttcattgtaa catagttttg aacaaaacgc tatcctacag aaagaggatt ggct
//
