LOCUS       NZ_LR135422            26633 bp    DNA     linear   CON 01-JUN-2024
DEFINITION  Enterococcus faecium isolate E8440 plasmid 4.
ACCESSION   NZ_LR135422
VERSION     NZ_LR135422.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA4885812
            Assembly: GCF_900639645.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26633)
  AUTHORS   Arredondo-Alonso,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) UNIVERSITY MEDICAL CENTER UTRECHT,
            Heidelberglaan 100, 3584 CX Utrecht, Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900639645.1-RS_2024_06_01
            Annotation Date                   :: 06/01/2024 05:45:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,282
            CDSs (total)                      :: 3,190
            Genes (coding)                    :: 3,081
            CDSs (with protein)               :: 3,081
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 34 of 109
            Pseudo Genes (incomplete)         :: 66 of 109
            Pseudo Genes (internal stop)      :: 28 of 109
            Pseudo Genes (multiple problems)  :: 15 of 109
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR135422.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..26633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /isolate="E8440"
                     /db_xref="taxon:1352"
                     /plasmid="4"
     gene            complement(9..860)
                     /locus_tag="FQ475_RS16030"
     CDS             complement(9..860)
                     /locus_tag="FQ475_RS16030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002287227.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            complement(961..1257)
                     /locus_tag="FQ475_RS16035"
     CDS             complement(961..1257)
                     /locus_tag="FQ475_RS16035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(1392..2885)
                     /locus_tag="FQ475_RS16040"
     CDS             complement(1392..2885)
                     /locus_tag="FQ475_RS16040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            3497..4450
                     /locus_tag="FQ475_RS16045"
     CDS             3497..4450
                     /locus_tag="FQ475_RS16045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            4422..4697
                     /gene="prgO"
                     /locus_tag="FQ475_RS16050"
     CDS             4422..4697
                     /gene="prgO"
                     /locus_tag="FQ475_RS16050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            complement(5601..5771)
                     /locus_tag="FQ475_RS16055"
     CDS             complement(5601..5771)
                     /locus_tag="FQ475_RS16055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_073490843.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHKYEYYIGY"
                     /name="hypothetical protein"
     gene            complement(5768..6118)
                     /locus_tag="FQ475_RS16060"
     CDS             complement(5768..6118)
                     /locus_tag="FQ475_RS16060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002326767.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTEE
                     VAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIRHI
                     EFYQDNKWGRLE"
                     /name="hypothetical protein"
     gene            complement(6111..7436)
                     /locus_tag="FQ475_RS16065"
     CDS             complement(6111..7436)
                     /locus_tag="FQ475_RS16065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_002342448.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLATVG
                     VGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRLNQIG
                     IMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
                     /name="Y-family DNA polymerase"
     gene            7953..8768
                     /locus_tag="FQ475_RS16070"
     CDS             7953..8768
                     /locus_tag="FQ475_RS16070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_002326780.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELEK
                     YLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIARI
                     DDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEADENY
                     NVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDLEALL
                     SANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
                     /name="helix-turn-helix domain-containing protein"
     gene            8894..9151
                     /locus_tag="FQ475_RS16075"
     CDS             8894..9151
                     /locus_tag="FQ475_RS16075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002326781.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIFM
                     IVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
                     /name="hypothetical protein"
     gene            complement(9403..9975)
                     /locus_tag="FQ475_RS16080"
     CDS             complement(9403..9975)
                     /locus_tag="FQ475_RS16080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(9991..10596)
                     /locus_tag="FQ475_RS16085"
     CDS             complement(9991..10596)
                     /locus_tag="FQ475_RS16085"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            complement(10997..>11566)
                     /locus_tag="FQ475_RS16090"
                     /pseudo=""
     CDS             complement(10997..>11566)
                     /locus_tag="FQ475_RS16090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769338.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /name="FtsX-like permease family protein"
     gene            complement(11618..12298)
                     /locus_tag="FQ475_RS16095"
     CDS             complement(11618..12298)
                     /locus_tag="FQ475_RS16095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001067799.1"
                     /translation="MNPFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            12445..12528
                     /locus_tag="FQ475_RS16100"
     CDS             12445..12528
                     /locus_tag="FQ475_RS16100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            12653..13390
                     /gene="erm(B)"
                     /locus_tag="FQ475_RS16105"
     ARG             12654..13387
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13653..14516)
                     /locus_tag="FQ475_RS16110"
     CDS             complement(13653..14516)
                     /locus_tag="FQ475_RS16110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016301 - kinase activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="WP_074394525.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGSG
                     KTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEALIS
                     RLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYETMY
                     ADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISP
                     KETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTPPIPKT
                     PKLPGI"
                     /name="zeta toxin family protein"
     gene            complement(14518..14790)
                     /locus_tag="FQ475_RS16115"
     CDS             complement(14518..14790)
                     /locus_tag="FQ475_RS16115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="WP_002331065.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEVN
                     LLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
                     /name="antitoxin"
     gene            complement(14807..15016)
                     /locus_tag="FQ475_RS16120"
     CDS             complement(14807..15016)
                     /locus_tag="FQ475_RS16120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="WP_000527318.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAKN
                     GGNVKEVMDQALEEYIRKYLPDKL"
                     /name="peptide-binding protein"
     gene            complement(15115..16011)
                     /locus_tag="FQ475_RS16125"
     CDS             complement(15115..16011)
                     /locus_tag="FQ475_RS16125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_002334978.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYFK
                     GGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGN
                     LASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTV
                     PTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLV
                     DTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYEN
                     VFFEMIERIIQLENEKE"
                     /name="AAA family ATPase"
     gene            complement(<16181..16285)
                     /locus_tag="FQ475_RS16465"
                     /pseudo=""
     CDS             complement(<16181..16285)
                     /locus_tag="FQ475_RS16465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636359.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(16309..16881)
                     /locus_tag="FQ475_RS16130"
     CDS             complement(16309..16881)
                     /locus_tag="FQ475_RS16130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="WP_001079938.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEE
                     AGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYK
                     IKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGG
                     QEPESRMIEPISLGFYEQNWYLIGFAG"
                     /name="HTH domain-containing protein"
     gene            complement(17157..17951)
                     /gene="aph(3')-IIIa"
                     /locus_tag="FQ475_RS16135"
     ARG             complement(17161..17951)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(18044..18586)
                     /gene="sat4"
                     /locus_tag="FQ475_RS16140"
     ARG             complement(18048..18586)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(18583..19491)
                     /locus_tag="FQ475_RS16145"
     CDS             complement(18583..19491)
                     /locus_tag="FQ475_RS16145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="WP_001255866.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDI
                     TYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLL
                     PLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPY
                     VIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLW
                     EKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKY
                     TGKTGCLDSTYAADIEERREQ"
                     /name="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
     gene            complement(19524..20258)
                     /locus_tag="FQ475_RS16150"
     CDS             complement(19524..20258)
                     /locus_tag="FQ475_RS16150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            complement(20239..21108)
                     /locus_tag="FQ475_RS16155"
     CDS             complement(20239..21108)
                     /locus_tag="FQ475_RS16155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_060763469.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIYY
                     NSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIKRV
                     EQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIYPTA
                     LKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYCINEK
                     KAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            complement(21123..21347)
                     /locus_tag="FQ475_RS16160"
     CDS             complement(21123..21347)
                     /locus_tag="FQ475_RS16160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000205227.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLDE
                     LKAIADVLGVKFVQAFILPDGEEIKISNE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(21490..23052)
                     /locus_tag="FQ475_RS16165"
     CDS             complement(21490..23052)
                     /locus_tag="FQ475_RS16165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000136908.1"
                     /translation="MTEKNIMVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSS
                     YEVQVSHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKS
                     ISRFARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQ
                     NVKLGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGI
                     GRALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVP
                     QYYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMIK
                     TLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQIL
                     LVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKSGIE
                     MEI"
                     /name="recombinase family protein"
     gene            complement(23054..23470)
                     /locus_tag="FQ475_RS16170"
     CDS             complement(23054..23470)
                     /locus_tag="FQ475_RS16170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WP_000323438.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQA
                     GIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFTSP
                     PPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
                     /name="recombinase"
     gene            complement(23471..23968)
                     /locus_tag="FQ475_RS16175"
     CDS             complement(23471..23968)
                     /locus_tag="FQ475_RS16175"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="WP_002327635.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDRE
                     RMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSA
                     SGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKV
                     VR"
                     /name="DNA recombinase"
     gene            complement(<24279..24956)
                     /locus_tag="FQ475_RS16180"
                     /pseudo=""
     CDS             complement(<24279..24956)
                     /locus_tag="FQ475_RS16180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /name="DNA topoisomerase"
     gene            complement(24972..>25241)
                     /locus_tag="FQ475_RS16185"
                     /pseudo=""
     CDS             complement(24972..>25241)
                     /locus_tag="FQ475_RS16185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            complement(25296..25976)
                     /locus_tag="FQ475_RS16190"
     CDS             complement(25296..25976)
                     /locus_tag="FQ475_RS16190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001067799.1"
                     /translation="MNPFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(26409..26621)
                     /locus_tag="FQ475_RS16195"
     CDS             complement(26409..26621)
                     /locus_tag="FQ475_RS16195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002324171.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIEY
                     RTEYLELTNQTDFLLIRKQQEQEKN"
                     /name="hypothetical protein"
     ARG             complement(18587..19491)
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(18045..18586)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             complement(18584..19491)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="109.42"
     ARG             12654..13390
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          complement(1393..2885)
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ctccataatt atttatcttt cattggaagt tctaaatcac tactgttcca aaaaatgtat
       61 ggtttgtttt gacgaatatt acttccatct aaccacaatt ttccgatgcc atatcgtagg
      121 cttgcttcga cttcataaaa attgtagatc tcttttcttc gatctattgc tttcatttcc
      181 tggccatttt ttaaaataga tctgatgccc ttaacagtag attcatggat actcgtgtga
      241 acgatatccg tattgatcaa ttcgtcatat cttccaaaat caacattgta ctcataacca
      301 agaagtgtcg gaatcaggtc aatttcaatt tctttttcaa ttgaacgttt aataagtttc
      361 gtggatacat acccgacaaa aaagagaata atacccactt caaacaaata catgtgtcca
      421 tttacaaagt gaataaacgt caataaaaaa tccttcactc cttttgttgt tcttccagat
      481 tgttcaattt gttttattaa agtcgctaga attgcattta caacaattaa atcgaatagg
      541 cttttgaaaa gttttcctgc tgttaatttt tgcctggtaa attgcatgac taattgagta
      601 aaaatagaca atagcatgac aaaaatcaac gtcattagca ctgtaaaaat gtctgatgct
      661 gcaatcctat tgggatcatt tatcaagtaa taagccgttc caaatactcc aatcgagtaa
      721 acggttaaat caagaataag tcgtgccccg taactacaaa gttttcctaa tggccataat
      781 tgcaataccc aaaatttctt tcgtttgcta tttcttttca gaggaagcca ggtgtgttca
      841 atccagtcgt ccgatttcat ttcgatttct tccctaaatt ctttccttta acgttttcct
      901 ttgctacttt agcagcgata ggttgctcaa tgaaccaatt ttttaagtaa ataaaaacta
      961 ctactggata tacttcttcc tttttcttaa ctcgttagct attttatact caatatactc
     1021 ctgctctaac acacacaaac aatcatatac ctgatccata gtctccccag aagctaagga
     1081 caacccatga agaaactcaa tcggcaaaga agcaactgtt ttttccctgg taacccaaga
     1141 agacaaagtc ccctgcttaa aaccataaag ctcacagaac acttccacag ataatcccaa
     1201 acgaccaatg ataaacacat taacaggatg tgaatagaca taatttttta acgacataca
     1261 acttcctcca tgatacataa gactgcatac gcagttataa gtataccacc tacacgtagc
     1321 taggcaaagg gagcaacacc tacagaagta tcatagatat attgtataag gcaatttgca
     1381 ccttttattt ttcaacctgt atctacttca aaaagattca cttctttaag agggttcaag
     1441 ggggttgata attgtctaaa tgtctcttct actaagctct cgttgagtcc aaatacctct
     1501 gtgatccttg ttgaataatc tagtctcttt tctttactta gttgaataac cctcgcgaac
     1561 aacgttttga ctgaagcaat gatcattccg ccatttcttc ctcgtgttac cttgtagaag
     1621 actttattct cctctcgtaa ctcatttaag atcttatcaa gtgttcgctt gggcatcgtt
     1681 agttgtgaag ccaattcttt ttttgacagg ttcaaataag gctcactagc aagacttttt
     1741 tcgcttagat aagccaatag atcttctttc cattcatttt tatgactata ttttctttga
     1801 tctcgtggct ttttaaattt ccaccagcca cgtcgttgaa tgaacagatc attatttttt
     1861 aaggttggtg aaacccattg ctggcacaat tcaataatga attctctgct tgctgcttga
     1921 taattaccag aataagcact acgtacaatc tttactaatt ctgcttcaga tagcggttcc
     1981 tgtaaccgtt cgttgaatgt gaacatattg tattcgcaag tatccaatgc ataacctgaa
     2041 gagtaataag ctaaagaaag cgtgaaaatc acattatttc gaccaagacg tccttctccg
     2101 ccgacgatgt ttgctttatg aagtaacata tcgaaccacg gttcatctac ttgacgaatt
     2161 tcttttttct caggaaagac aattagtttt cgttctcgat cttcttttgt tttttgatct
     2221 gattcaagct tcatcgacca ttgaatccag tcagcaaaag aatactgata gttcatttct
     2281 ttaaaaacaa tattattttc ttgtgggaat cgagcaattc cgaagtggtt acatcctaga
     2341 tccactccgg acaatttttc agccaactgt agacgaattg tttttgaaat tttttttgct
     2401 acatcgatca ccttgaaatt gcttttcttt gtgacatagc ctggtgtctt tagtacaaaa
     2461 taaacttgat aaccatgatc tgattctaaa attagcgttg gcatgtagcc cacttgatct
     2521 aaacaggcta aaataatttc gccttgatgg ttctcttttg aatcgatatc aactacaaat
     2581 gtgttgattt gacttaagtt tttctcagaa tgacctttaa ccactgttcg ataatcatcc
     2641 gcataagtac caaagcgata ggtattaggt gtccaatgcg ttagtttctt ttcgttctct
     2701 aaaatagctt cttccgaagt aatgaccata ccacgcccaa cattcattaa ttgcttgcta
     2761 cggtacgcaa agatagcacc actcctactg gaatcaatat gacctgcagg tttcatggtg
     2821 ctgtttcgat atttgtatgt acgtaagccg tttttaagaa tagctgaata aatttcgctc
     2881 aacatcgatt gtaacgtcct ttctcaaaca aaaagagaac acagtttagc tttaatctca
     2941 gccatagtat gtgttctctc ttcagtgttt aagaatattt aatttaagta cactaaataa
     3001 acgttcttct gttgagttgc tcgccttttt ttggtagaat aaaggcaatc ggaaaaggta
     3061 tccgatcaac ttttaatata agtagttggt agctacttac atattcttga gacgagcgtg
     3121 aacacatgtc ctaaccatgt gattcagaaa taattgattc tgctaaaatc aattatttcc
     3181 gtctcttttt tttatgtaat ttttctgttt aaagagtacc actgcttttg ctactttgta
     3241 aatagtgaat tatctgtggt ttctatagaa ttaagtttac ctcttttcac tctaaattgt
     3301 caacgcaaaa cgcacaaata tattttgaca ttttgaatat atctgatata ctgaatatag
     3361 caaatatatt tagtatatcc actatattcc ttataaagtc tgaattctta tcaatttgga
     3421 gtatattaga tatatcgaat atattaagta tatgaagtat actaaatata tttagtatag
     3481 gaaattggag ggaactatgg aaaacttacg gactgcattt aaaacatcag ataaactagg
     3541 aaaagttgta atgcttacag gtagaaaagg cggcattggt aagactacag acaatgattt
     3601 attagcgatt gtttctagtc aactttttga aaaagacgtg ttgctaattg attatgacca
     3661 acaaagaaat actacttcca acattggatc aacgtatcaa attactagct ttgatcgatc
     3721 catgtctgca gcaatcaaaa aaggggactg ggtttcaggt attactcaag taagtccaca
     3781 tttatatatt atggctggct ctcctggatc tgaagaactt aatgaatact tgtccgaaaa
     3841 atatcctgat cgtcgtaaga gatcattggc cttcattaaa cctttagaag aattgagaaa
     3901 aaatttcgat tatatcttta tcgactgccc accatcaaca gataatgtgg ttcgtgcatt
     3961 cttaactgct gcagattata ttattgcaat gcaagaatta aaacggtacg caatggaagg
     4021 aacagaagat tttattaata aagttttagt tccgattgtc acgaattttg aagagtctca
     4081 tcttcaaatc attggaattt tgcctgttct tttctcagtg cgacgttcct ctcaacacgc
     4141 aaactatcaa aaaacaattg ataagtatgg tgaatcaaac atttttaaaa gcattgttaa
     4201 aggctcggat cggttagaaa tgtatggtga gaatggtatc caattaaatg attatgtaga
     4261 tcgaagatgg tgggctattt ttgcagacat ctttacagaa ttagaagaaa gaattgaata
     4321 ctatgaacaa catggtgata ttgaaggatt tgattataca cctaaatatg ctgactcaat
     4381 ggccaatcat atcctacctc ttggaaagga gattaaacta aatggcatta ttaccaacga
     4441 acaaagataa gaagaaaatt ggtgctgaag atatttcaat taaagatgat attaatgtcg
     4501 agttagggga acgaaagtac actgcgaaag aaagaaaacc agttcaagta gatcctcccg
     4561 tactaaaaac cattcgggat cttagttatg caaaagatat tcctatgtat gaaatagtca
     4621 aacttgcaat ggacgcctat gttgatactt taaacgacga ggaacggatt atatataata
     4681 gacgatcaaa agattaaaat atagtaagta tactagatat agtaaatata tttagtatac
     4741 ttactatatt tttagcttta ttaatcctaa tccttcaaaa tatgtgtatt gtttgggggt
     4801 atacaacatt cacaaatttt attgtttcta gtttttacta tactaaatat atttaatata
     4861 gtgagtatag taaatatatt ggtttttatc tacaggtaat ggtggtttta acaaacatat
     4921 agttacagtt actgaagaac agtccgttag tcagcaggag taagtaataa atcgtttgtg
     4981 agacactatt ttgattgata cgacctctaa ccatgtgttt gtttcattta tgttataata
     5041 agaatgtaag catattaaac agcaaactat cacagcagca ctagactcaa tcaaatgaag
     5101 ggggatggtg ctaatgaaaa aactactagc aatttccctt atcctaaaaa ggagaattaa
     5161 tagtgtcaaa agaacctatg tccgcatgga tgcagctcgc tcttagcatc ataaagctga
     5221 tctctaattt tgtggcttta gacaatagag caaaggttct aactacgcaa tgtttagtaa
     5281 tacttacttg tagcctactg gttgtaatag tatttctttt acttgcgtta ttcgtagtac
     5341 accttttgtt tttttaaaac aaaagaagct tattcaacta tatttagctg aataagctgg
     5401 tctcaatgtt aaatcaagtt tgttggacgg gtttaacatt gctttctagt gctattttag
     5461 ttagctctag tatgcttcaa gctagttaca acgtcctaag gttgtaacta gtttttttat
     5521 attttttaat tacctatagg taattttatc agaattgata caaaatgtaa aacataaaag
     5581 aaatataatt ttattgcact ttaatagcca atatagtatt cgtatttatg gtatcctgct
     5641 gcagcttcta catagaaaga gaagcgttca acaccaacct catttatcaa acgctggcca
     5701 taaccccaaa tctcttctga tagctgatca aaggttatat actttagctc atattgctgg
     5761 ataatgttca ttctaatcga ccccatttat tatcctggta aaattcgata tgacgtattt
     5821 cgtcgtagtg aactttgttt tttccaacgt agatccccag ctcatcacta cctaagatct
     5881 tgctaacaat atcttctgga tagtatcctt cagcgtttcg ttcttctttt tgaatacata
     5941 ctgatctatt ttttatgact gcagcgttca atacttccgc aacctcttca gtcgtcattt
     6001 gttcttttgc caaattttga ttggctcgtt gttcattgtc ggcatcaatt ttttcagtat
     6061 gatcagataa ataaaaacct gcccacttta aacgtccacg atcattataa tcaatcattt
     6121 ttaagccctc ctgcgccgcc tgcatggcca ccaaccaatg tacttctagt aatactacga
     6181 gcgccttcta acatagaaga agcatgtaca atcgacgtaa aaccatattt ttgccgaatc
     6241 ttgtcaataa ttttatctaa attttcttcg tcaatttgct tttgtggatc actaaataaa
     6301 tccagctgaa gcgaatcagt gtacacaagc ttgctatagg ttattccaac gtgccttact
     6361 tcttgtcctt cataatactt atcaaacaag aaaagacagt aattctgcaa ttcctttgta
     6421 ttatctgtta tagggatctt catctggtgt gaaaaacctg gtctcgtttc taagatcgac
     6481 gtgccaatgt ataaatggac acaacctgtt ttacagttat gttgcctgat acgaatagct
     6541 acttgttccg ccatttcttt taccaccagt tcgatttcat ttctcctggt ataatctcgt
     6601 ggtaacactt gtgaattacc atatgatttt tcctttgtcg gttctggtgg gatcgctata
     6661 tctgttcgat cgatcccgtt cgcatgaaaa tacagctgta agccaatcac acctaaatgg
     6721 ctcttaatag tgtatggatt ccaattagct aagtctttaa tactcatgat accaatttgg
     6781 ttgagtcttt ttttcattcg agatccaata ccccaaaggt ctgtcatttc aggaatattc
     6841 catactttat caggaacatt ttgatacgtc cattcagcaa ggaatccatc attatgtttt
     6901 gcttcattgt ctaaagcaag tttagctaat aagggattat ctccgacacc tactgtagca
     6961 agcaatccta gctcttcttt aatattctcc tggatcattt gagccagctt ctttctccgt
     7021 tgacttcttg ttccttcagt cgtaaaaaga ttcattgatc tggtcacttt taagatcgat
     7081 tcatcgatcg agtaaatcaa taaatcttcg tctgctacat accttctgaa aatattgttt
     7141 acctgcatat ttcgcttaat atagagattc atgcgtggtg gaacgacatg taacgtttta
     7201 ggaaaaggtt gcggtagatc tcgtggtcga ctgacattag aaataccgta cttcttcttt
     7261 gcagctggtg aagaagctaa aatcaaccct gatcctgtat tatccgctcg actcatgacg
     7321 actaattcag tcgttaatgg atctaaattc ctttctatac attcgacact tgcgtaaaag
     7381 cttttcatat cgatcaaaaa gtaatcattt actggctctt ttgaataatc catcataaat
     7441 aacactccat tcttccacat tatacaaaca tacgttcgtt tttgtaaaga agaatcgatt
     7501 aaatgtacaa aaaaagaagc ataggtaagt tatttcccta cttcttctgt tgatttgtaa
     7561 aatcaacaca ttgtatcact ttattaaatg gatatttact attagtcttg tgaaaatttg
     7621 aaaataagtg tcgtattatc cagttttgct tagttatatt agaaaaaaat aagaaattca
     7681 aaaaagaaaa aactttcctt aaaaacaaaa aataggagta ttcagtttct taatagtttt
     7741 gtaatagttg tatgtagaag ttttcttaat agtttttgta ataatttatt aatcgtagtt
     7801 tatataactt atttgtaagt gactagagaa ttaaataaaa aataattact atctagtacg
     7861 aaattaatta cataggataa tatattaagg tgctggacta caagtaaaaa atactgtatg
     7921 atcatgacag attcaagaaa ggagcaataa gattggttaa gatagcagga ctttctaaag
     7981 gtggaaaaac cgtttcacaa ctttataaac aaaactacag agactggaga cagttcagaa
     8041 aaaacattaa ggattcttac tttattctac caacagaact tgaaaaatat ttaccgaata
     8101 acaaagctat taatttatat ctgtattact gttttaaggc aaagaatgaa ggcggggatt
     8161 cctggcattc ggtcaatacc atagcagagt ctctaggagt gacaactaaa actataaaca
     8221 cctggaataa aaccttagtt gatttaggta tgattgcacg tatagacgat aaccatctca
     8281 gtaaatcgac aattttactt cctctctcta gttactataa attagccctt gatagttctt
     8341 taaaggatgt taccgagagc actgtccatg aaattgatgg caacttggtt gcagtttatc
     8401 atttgtttga atggagaaaa aatgaggctg atgaaaatta taacgttcct tataacacac
     8461 tctgttgtgt ttttaaaaga aaaacacaaa aagatactat ctataaattt atcttggtcc
     8521 aagatgagaa aataagtaat ttcgaattaa gcactccttc tagtaagatt tatgacgatg
     8581 catatagatt tgaatgtcaa gatctagaag ccctcctttc cgcaaataat ctaaacaata
     8641 tagaacatga aaactttgtt gtaaacacta gatttaattt agtttctgaa aaggactcag
     8701 atttgttaga tttgctgata gagcttacta aaaatctaga taagaaagaa aacattactg
     8761 tactataact agcatcggtc catcattaag tttggactat tagaacactt gctattacag
     8821 aaaaaggtat gctagccacg cttactattt attggtatca aacaagtatc ttaatttgaa
     8881 aggaagatga tttatggcta atttatatat agagaacaaa ggagacttga atgccattat
     8941 tactttaatc gtagttatgg taaaatcaat aggtaatatc acaataggaa tgctgtttat
     9001 tatattagca gcagtgctga tttttatgat agttatttgg ttcttaaatg aaagatctaa
     9061 agacaatcaa caccgtaggg atatggagat aaaatcaata gagtcaatag attatttatc
     9121 gataataaca ctaaaaaagc cacgttccta aacgtgactt acgctgaacg atatgtgttg
     9181 tttggtagac gaacaaatcg ttcattataa atatatgatg gtatcctaat atagtaagcg
     9241 tggctagcat acctttaatt actttacctt ttacagttac catacacatt ttttgagcag
     9301 aaatcaagta aataaaaaaa tattatattt cacaacatgc taatagactc atatctagaa
     9361 cgcattaagt atttacctgt ctggttcgct gagacttctt ttttaacttt cttcaatttt
     9421 cttctttatt ctaaaaagcg tactgcgact gaaaccggtt atagcttcaa cttccttata
     9481 cgatttacct gaagtaagca gttcatatgc gtgcctcttc ttcggtgtga ttgttgcttt
     9541 cggacgtcct tctctgaaat taggattatt ctttcttgca aacatttttc cttcttgggt
     9601 acgttccaca atcatatcac gttccatttc tgctacactc aacaacgtcc gtgtcaccat
     9661 tcgccccatg gacgtatttt caatcgttcc tagattcaaa accttgatcg ttacgttatc
     9721 atcgagtaaa ggttcaatga tctctaatgc ttctctcgtg ttacgagcaa atcgatcaag
     9781 cttcgtaaca actatttcat ctccaggctt cagaccagcc aacagctgat tgaattttgg
     9841 ccgatcccgt tttgtacccg taaatttttc tgaaaaaata ttcttcttct ctacgccgtt
     9901 ctcaagcaac tgttgaattt gttcttttgt actttgagaa gcggttgaga cacgtgcata
     9961 tccatatttc gtcatttggt ccacctactt ttacaaatca tctatcgtat actcagaata
    10021 cccttcatag aaatagctga catcgattcc tttcatatat aactcgcgat cgtcaatttt
    10081 atcagtcaga gcattggaaa ttagatagcg tatttccaaa tcgtttatgg gacttcgctc
    10141 cattgcagaa agatagtctg ctttatcgat taagttccaa tctacaactt tttgcaattc
    10201 ttcctttaaa atgagatcca gccaaattct agtacttcgg ccatttcctt ctcgaaatgg
    10261 gtgagcgata ttcatctcca catatttctt gataatctct tcaaaagaag tttgtggcat
    10321 ctgatcaata tgctgtaacg aatgttctaa atacataact ggtgcaaatc gaaaatttcc
    10381 ttttgcaata ttgaccgatc ggatttttcc ggcaaaatcg taaatatccg aaaatagaaa
    10441 ttcatgaatt tcagataaac ctttaaatgt accaacttcg atttcattta tttttccaca
    10501 atcgtacaat tctttcgctt tttgtttact gagtttttct tcaaccttag ccaactcaac
    10561 ttgattggtt aatcccaatt tattctctaa aatcatgcga aatctcctta actttatgac
    10621 ataagtttat gaaacactct caaccccatt atatcgcgat tttgtttatg tgtcaaaaac
    10681 tattaagttt ctgacccccg atagattttt caagtgtctc tattttgcac agtctagttg
    10741 acctttgata cacctctata tttatagaga atctaaaaca tcaacatggc atactcaaaa
    10801 ttctaaatat tagggataaa gaattctcct atacaatcaa aaatttcctt tatttcgaac
    10861 tccggtcacc taactctatt gatctcttac aagccaaaga atatctctat actacaaaga
    10921 aacaataggg tgcctggttg gtctctttgt gttttatttt agaatctaga acgtaaatat
    10981 tcttgtcatt ctgattttat ctaagaatat caattaaatc tttttttgca gcctctgaag
    11041 cgggcattac agaaaagacc agtccaataa ccgaagatac cccaaccgct agtaaaatag
    11101 taaatagatc aagtgacacg tttaccttta tcaaagaacc aacactataa gcaagagcca
    11161 ttcctaataa atagccaatt aaccctcctg aaagagttaa aatcaaacct tctaaaagga
    11221 actgcagcat aatcgatttt cgagtagctc ctagggctct tcttataccg atctcttttg
    11281 ttcgttcaga tacagatata tacatcatgt tcattacacc tacccctgcg ataaataaag
    11341 atatacctgc tacagctgtt ataaaataag tgatcgtact gaggatttga ccaattcctt
    11401 tcgttaacat agccgtatct aacacttcat attcccccaa atgtttcaaa ctaccttttt
    11461 ctttcaattg gtttatcact ttagaggtca ccttgtcagg ttcaactcct tcctctaaag
    11521 ttaacgttag agacgatgta tccttttcag acttaaaata ataggttctg ttgcaaagtt
    11581 ttaaataaag aataaaatcc cttacggtat ctatgattta agctgggatt cccaataata
    11641 ccttgatttc agtacagacc gaaaacccga agagagtgcc ttcttttcgg gttttcttat
    11701 ataatcctcg aatggcttcc atgcctttaa tcgtggtaga ggcagtgcgt aaacttcgat
    11761 agaatttatt gcgtctcttt actggacgat ggtcttgttc aatcaaatta ttcaggtatt
    11821 taatggtacg atgttctgtc ccttgataaa agccgtattc ttttagtttc ttaaaggcac
    11881 ttgtaataga gggggcttta tctgtgacta caaccttcgg ttcatcaaac tgcttcacta
    11941 accgcttaag aaaagcatag gctgcttgtg tgtcccgttt tttacgtaac caaatatcca
    12001 aggttaaacc atctgcatcg atggctcgat acaaataatg ccattttcct ttaattttga
    12061 tgtacgtttc atccattttc catgaataaa aggatttttt atttttcttt ttccaaattt
    12121 gatagagtag tttgccatat tcttgcaccc aacgataaat cgtcgtatga gaaacgttaa
    12181 tgccacgatc atataagatt tcttgaactt cacgatagct aaggttataa cgaagatagt
    12241 agcccacggc tacaataatc acatcctgct gaaattgctt tcctttaaaa ggattcatcg
    12301 tcattcctcc tgctatcttt ttctattatt ctaccttatt tgatagtaga tttaaaactt
    12361 tgcaacagaa ccaaaatttt gtataatagg aattgaagtt aaattagatg ctaaaaattt
    12421 gtaattaaga aggagggatt cgtcatgttg gtattccaaa tgcgtaatgt agataaaaca
    12481 tctaccgttt tgaaacagac taaaaacagt gattacgcag ataaataaat acgttagatt
    12541 aattcctacc agtgactaat cttatgactt tttaaacaga taactaaaat tacaaacaaa
    12601 tcgtttaact tctgtattta tttatagatg taatcacttc aggagtgatt acatgaacaa
    12661 aaatataaaa tattctcaaa actttttaac gagtgaaaaa gtactcaacc aaataataaa
    12721 acaattgaat ttaaaagaaa ccgataccgt ttacgaaatt ggaacaggta aagggcattt
    12781 aacgacgaaa ctggctaaaa taagtaaaca ggtaacgtct attgaattag acagtcatct
    12841 attcaactta tcgtcagaaa aattaaaact gaacactcgt gtcactttaa ttcaccaaga
    12901 tattctacag tttcaattcc ctaacaaaca gaggtataaa attgttggga atattcctta
    12961 ccatttaagc acacaaatta ttaaaaaagt ggtttttgaa agccatgcgt ctgacatcta
    13021 tctgattgtt gaagaaggat tctacaagcg taccttggat attcaccgaa cactagggtt
    13081 gctcttgcac actcaagtct cgattcagca attgcttaag ctgccagcgg aatgctttca
    13141 tcctaaacca aaagtaaaca gtgtcttaat aaaacttacc cgccatacca cagatgttcc
    13201 agataaatat tggaagctat atacgtactt tgtttcaaaa tgggtcaatc gagaatatcg
    13261 tcaactgttt actaaaaatc agtttcatca agcaatgaaa cacgccaaag taaacaattt
    13321 aagtaccgtt acttatgagc aagtattgtc tatttttaat agttatctat tatttaacgg
    13381 gaggaaataa ttctatgagt cgcttttgta aatttggaaa gttacacgtt actaaaggga
    13441 atgtagataa attattaggt atagggcacc tctaataact accaattaat tcacctcaaa
    13501 atgaaattag aaaaaaacag cgaaattttt aaatctattt cttatcgata caaattcctc
    13561 gtaggcgctc gggaccccaa catgaggaaa tgtttttata aaaaaagagt agttaccgtt
    13621 ttttggtaac tactcttttc cttttttaag gtttaaatac ctggaagttt aggtgttttg
    13681 ggtattggtg gtgtaggtag ctgcaagctt tccatttttt gttgaattgc tttaaattca
    13741 ggggtttctt ggtgttgatt ttgaaccatt ttttgctcta ttctctccaa agtcggttga
    13801 atttctttcc ctgatacttt acgatttaat tctctttcta aggtctcttt cggactaatg
    13861 gaaggcgttt ctaagcttga atagagtttc actccttctc tattgtaaag ccttatatcg
    13921 ctaaataagc ccgttttatg aagggtttct aaattggtcg gtaagttttt gacaacaata
    13981 tcatgcgctt gttttggtgt tgccctagct gtcattggat catctgcata catggtttca
    14041 tatcgttcaa tcgttcctaa gtatgattca attttcggta ctgccatgac gtatattttt
    14101 gtttcataac ctttagattg aagcattgtg gctgtttgaa tgggaacgtc tgttgttcgt
    14161 cctgttcctt caatcactaa attatagcct tgatcgctta aacggctaat aagtgcttct
    14221 gtcatgcgat tcgaataagg ggtaacgtgt tttactacgt ctttttcata gagtttcact
    14281 aattcgtcaa aatttgggtg ctgttgttta aaggtatcat tatcaatgac aataacattc
    14341 ccttgtgttt cttcaaaaat tgctgatcgc aaactggttt tccctgaccc tggttgccca
    14401 ccaagtaaaa aagcggttgg cgattcaacc gctagtctat ttttagttag tcgttcaaca
    14461 ttcttttcta aacgatcttc aaattgcttt tcggtgaagt cagtaatatt cgccatgtta
    14521 agccactttc tctttattca aaatttgttt tgaatattga ttcattgacc gccaatactc
    14581 atgaatagct tgtaattctt caaatggttg ttgaaataaa tcaacttctt gtgccacttc
    14641 taattgattt aaaagattca cttctagtaa acgagtattt ttagtatcta gttcatgatt
    14701 caaaacataa tttaataccc gattataaac acttgccgat aactcattaa tgatttcaat
    14761 ttcaaatgtt ttttcatacg taactgccat ttcattttca ctccttttaa agtttgtcag
    14821 gtaaatattt ccgtatatat tcttctaagg cttgatccat aacttctttt acgtttccgc
    14881 cattctttgc tgtttcgatt tttatgatat ggtgcaagtc ggcacgaaca cgaaccgtct
    14941 tatcccccat tatatctttt tttgcgctga ttggcgtatc atttcgtttt gctttctgtg
    15001 cgcctaaatt tcccacgatc gctcacttct ttctatttct tcttactatt tattttatca
    15061 tcacctatca caaatcacaa gtgatttgtg attaatcact tgtgatttgt gattctattc
    15121 tttttcattt tctaattgaa tgattcgctc aatcatttca aaaaatacgt tctcatacat
    15181 agacaaaact tttttgtcat agcctttgtg ttctgtaatg ccatttttag accaagtact
    15241 tactttatta cttcgcttga taatatttcg gaaaaccaaa ttatcctctt tatgttcttt
    15301 gtacagttct tccaggtttg attttatcgt tgcgctgtcc gtatcaacta aataaggaac
    15361 aaaaccaatc atatctagtc cagggttaaa ctgttcttgc aaatcaatca aataggaaat
    15421 atagttttga atgttgtttg tactttcttc ttctgcttgt aaagggatca taacgtaatc
    15481 actcgccacg attgcattat ttgtataaac gcttggcgtt ggtacagtat caataataat
    15541 aagatcatag tcacttttta aaggtgctaa aagagtagca agcaatctac tttcattttc
    15601 aaacgtccat gagcgagtta attttggcag taacatcaaa tcaaacgtgc cagggatcaa
    15661 gtctaaatta tcagtcaaat gaataataga agaagccaag tttccatttt tcaagccttc
    15721 ataaaaattg acacgtggca attctacctc aaaagttttt gctaagtctt ttgtcaatgt
    15781 tgcctgtaag tccttatcga tcattaaaac ttttaaattc aatttgtctg tcaagtaagc
    15841 aaacatagtc gataatttgg actttccaac accaccttta aagtaattat tcaagataat
    15901 aattgcttca tttttattgt ttaaaatacg tcttaattct tcaagtattt ttagtttttc
    15961 cttctccata actacgcccc attctttttt tgtatagtaa tattgtatca ttaagaatca
    16021 caaatcacaa gtgatttgtg attaatcact tgtgatttgt gataagtgat ttgtgattaa
    16081 tatataaaag ccctctttaa agggctttta tatttatttt gagaaagata taaaatcaat
    16141 atatcccttt tccccaattt ttacaacggc attgtagggc atatagtttt ttatatgaaa
    16201 gcatttgttt taatatttgt tccaaagagc catcatggct ttgacagagc tcttcttcta
    16261 tgcaaatgct tttaatccga tccacacgaa aattcctata ttcatttctt agcctgcaaa
    16321 accgattaag taccagttct gttcataaaa ccccagtgat ataggctcta tcattctgct
    16381 ttccggttct tgccctcctg atgcaggata ttgaattgat attacccttt tattgcagat
    16441 tgcagtctga attgctgcaa taacgttatc cgccaatgta tttttctgtc cagatgtgct
    16501 gtacacgtta atactgttct ccaactcctg tgcatagttt ttttcaccat gcttcaaaat
    16561 agatttgatt ttatacatag ctgaatcaaa atcctttata aatgattcat ctccatggca
    16621 atttaaaaat ttccctgctg taatcaatgc acccacttcc gccgctgtaa acattaccgg
    16681 cggaagtagg aagccctcta caagaaaata tccttttccg gcctcagatc caattggtat
    16741 tccggcttct tcaagtgtcc ggatatctct gtaaactgtc cttaagctta tattaaatcg
    16801 ctgtgcaatt tctttggcag gaattatttt ttttgattgc agctgaataa gaatagaggt
    16861 tactctgtta atcctgttca aattttattc ctcctctgtg acttccataa aaagtatatc
    16921 ctatgcgttc ttaagctagc tgctgttagt gcttctcatt gcaccctggt tataaaagcc
    16981 atactcacaa acctcttcac caaaactctt tacatctcta atatagaact ctatctagcg
    17041 aacttttaga aaagatataa aacatcagag tatggacagt tgcggatgta cttcagaaaa
    17101 gattagatgt ctaaaaagct tgtagttaaa gctttttaga catctaaatc taggtactaa
    17161 aacaattcat ccagtaaaat ataatatttt attttctccc aatcaggctt gatccccagt
    17221 aagtcaaaaa atagctcgac atactgttct tccccgatat cctccctgat cgaccggacg
    17281 cagaaggcaa tgtcatacca cttgtccgcc ctgccgcttc tcccaagatc aataaagcca
    17341 cttactttgc catctttcac aaagatgttg ctgtctccca ggtcgccgtg ggaaaagaca
    17401 agttcctctt cgggcttttc cgtctttaaa aaatcataca gctcgcgcgg atctttaaat
    17461 ggagtgtctt cttcccagtt ttcgcaatcc acatcggcca gatcgttatt cagtaagtaa
    17521 tccaattcgg ctaagcggct gtctaagcta ttcgtatagg gacaatccga tatgtcgatg
    17581 gagtgaaaga gcctgatgca ctccgcatac agctcgataa tcttttcagg gctttgttca
    17641 tcttcatact cttccgagca aaggacgcca tcggcctcac tcatgagcag attgctccag
    17701 ccatcatgcc gttcaaagtg caggaccttt ggaacaggca gctttccttc cagccatagc
    17761 atcatgtcct tttcccgttc cacatcatag gtggtccctt tataccggct gtccgtcatt
    17821 tttaaatata ggttttcatt ttctcccacc agcttatata ccttagcagg agacattcct
    17881 tccgtatctt ttacgcagcg gtatttttcg atcagttttt tcaattccgg tgatattctc
    17941 attttagcca tttattattt ccttcctctt ttctacagta tttaaagata ccccaagaag
    18001 ctaattataa caagacgaac tccaattcac tgttccttgc attctaaaac cttaaatacc
    18061 agaaaacagc tttttcaaag ttgttttcaa agttggcgta taacatagta tcgacggagc
    18121 cgattttgaa accacaatta tgatagaatt tacaagctat aaggttattg tcctgggttt
    18181 caagcattag tccatgcaag tttttatgct ttgcccattc tatagatata ttgataagcg
    18241 cgctgcctat gccttgcccc ctgaaatcct tacatacggc gatatcttct atataagcgt
    18301 accggttcca attttttcgc agtttaactt ttccgacgca tttatcgtct tggtagtaaa
    18361 gatatattat cttatcagta ttgtcaatat attcaaggca atctgcctcc tcatcctctt
    18421 catcctcttc gtcttggtag ctttttaaat atggcgcttc atagagtaat tctgtaaagg
    18481 tccaattctc gttttcatac ctcggtataa tcttacctat cacctcaaat ggttcgctgg
    18541 gtttatcgat atctttcagg tgccctgctt tcatttctgt aatcactgtt cccgcctctc
    18601 ttctatatca gcggcatatg tgctatccag gcagccggtt ttaccagtgt attttttata
    18661 catgtccctg gtatattttg ttatattcct atcatactcc ggataggcat aatgaagcct
    18721 ttccgccacc tcaccggata ccgccctgaa caattgatgg catagaaata atgcttccca
    18781 tatgttttca taggaatcca tccggtaggt ggacaaaagt ttctcccaca aatcctcgga
    18841 tatatacctt tcaataaact tatagttctt gcctacactt aatttaaagc ctgtttcgat
    18901 gccgaccttc catgatatca ttctcagcag ctcatggcga acaatctgat taaaatgatc
    18961 aatagcaaat aaaatttcct tacggcacaa tcctttaata acataaggtg ttacattcca
    19021 aaattcattg cagcaatcat catactccct tgcgcttggc tttcttacat gataatctat
    19081 atcagtcgga actatgtccc ttttaattct acaatcttta tcaattagaa cctttattaa
    19141 tttatcgccc tttaggtaat tatctaactc ttccaagggc aataaggtaa gatcaatttt
    19201 attgtaatca tcaaatagca taagatagga aaatcccttt tcttcaggtg ggaataattc
    19261 catatcctcc ggcttttgca tcattattat attcccaaat tgattaagcc agtcatcatt
    19321 agatataaac ggttctatat cacttacaaa atatgtaata tcataatcct gaaattcatc
    19381 tttaggtata ttaatatttg cgcgtgaccc ctcaagggtc acaattcgaa tacgttcatc
    19441 ctgttctgct aaagaaagta ctaaatccat catttctttt tctgatctca tttacatact
    19501 cctcgtttat tttttctata ttattacatc ttcttttttg ccgatacaat cagcatcatt
    19561 gggcgtcgca tttcatccgc catccccgga atatccatca tgttctctgg cggctgtggc
    19621 tccacaatct gatttattat aaaactattt gaaagcagtg tatttagata tgtggtcagt
    19681 gttctatgat attttgtaac cttttcttcc aaaaacatag ctgtccgttt gccctcataa
    19741 taataattgt ccaccgggaa atgcagtatt tctccttttt cgttataata ccagtcttgt
    19801 gttccatgag cagtaaaaac aggatgttca actgtaaaaa ctaaattgcc accagccttc
    19861 agcatcctat atatcttttt tattaaattc tcatagtctg ctacataatg aaacgcaagc
    19921 gaacttagta ttacatcaaa gctctcctct gggaaatcca catcttctat ggcacagcat
    19981 tcatattcaa tctgtggaaa atgggttttt ccttttgcta cttcgagcat tttatgagaa
    20041 atatcaacac ctactacaga ggaagcaccg ttttccatcg catatataca gtgccatcca
    20101 tagccgcatc ctaaatcaag cacacgctta cccttaaaat caggtagcat ctttttcaaa
    20161 gtctcccatt ctcccgcacc agccagtcct ttctgcgagc gactcatttg actgtatttt
    20221 tgaaaaaata tattatcatc atatttgttt tctttcatct gaactctcct cgtttaaaaa
    20281 gttatttatc tccgatacaa tttcattcac ttctttataa agtttctcgg tcatgtcgta
    20341 gcattcaaaa agagaaagac cgagtacttc aaaaatatga ttaactcttt cggcatattt
    20401 ttcaggttta tattcaaaag tttcaagcag ttttatagct ttcttttcgt taatgcaata
    20461 agcattatta catgcaaata gtacttgatt taagcatgaa ataatacgaa aaacatggcc
    20521 tgcaatataa tatttatcct ctgcccccgc atttgctttt acaaacatta aagagaattc
    20581 agcttcaaat ataaaaaagt tcatcaagct tttctttaga gcagtagggt aaatttctgc
    20641 ctgctttttt aattcgcata agctttcgtt cttagcatat agtattttac taatcgctaa
    20701 ttctccacga tacatagcac ttatataacc atggggatgc ccggtctgat aattggcagt
    20761 aacaattcct tgctccgtat ctttgattat ttgttccacc cgttttatat cacgtaatat
    20821 caagtcaaca tgacacccgt ttataactaa ccatccaccg ccattaaccc aatcacccca
    20881 cgctccggga ggtacaacaa ggttgtttct attctcatca tccaactctg tagcaatttg
    20941 attaatcgct gtcaggtcaa atgagtctga attgtaatag attccgatat ctatatcaga
    21001 attttctgta tgggtgcctc ttgcacgtga gccccctaat acgatgcctt ctataaaagg
    21061 caaagatgat aatttctctg ttactatttg aataacatta cctaccatat aaacatcctc
    21121 ctttattcgt tagatatttt tatttcttct ccatctggta aaataaatgc ctgcacaaac
    21181 ttgacaccta gcacatcagc aatggccttc aactcatcca aggttactgt ttctcgttgt
    21241 aattttttat tgaaattctg tggagtctgg ccaatacgtc tagcaagttc ggaaacactt
    21301 atattcattt gctcacacag ttctttaatc atttctgccg tagtcataca gcacctccaa
    21361 gtttacgcta agaatattat aaaccatttg gttgataaac acaatagtta ttaaaatatt
    21421 attataatca gcaagcaaaa gaaaacccac aactctactg tagagtcatg ggctatttac
    21481 ttctggtttt catatttcca tttcgatgcc agatttgaag gctatgacga agtggccttc
    21541 atagactgta acgctctgga ttatcttcct tacaagctta tcatcatatt ctaaggtgcg
    21601 gaatttgttc ttgcggataa attcaatcag ctcattgatt cgctcgttct cgccactgag
    21661 ggaggcatct tctactaaaa ggatctgtcg cttgtctctc agctcatcaa tctcatctgc
    21721 taagtggtca tagtcttgac ccttgttcgc cagcttgatt agttcttttt gtttttcctc
    21781 tagtgagttg ttaatctctg aaatttggta ttctgtggtt tcgccaatca cagcatgaat
    21841 attctcttcc agtgtcttta tcatattgtt cccacctgca agtagcttat taatcgcagt
    21901 cattactgca ccataaagtt catcttcttt tacggttcgg ttcttacaaa cttcaggacc
    21961 ttgctcgatt ctagtcacgc atcgccagac aaattctttt cttccgtgga tattccaata
    22021 gacccgtcta taaatatcgc cacaatctcc acagaaggtg atggcactta aagcgtactt
    22081 gctactgtaa attcttttgt tcttgccttc tcctgtgtag atattgcttc tccgatgaat
    22141 ttcttcttgc gcctgcaaaa ataactcttt aggaataatc gcttcatggc tattttcaac
    22201 ataatattgg ggaacatgcc cttcattttt cactcgtttc ttggtcagaa aatctactgt
    22261 gacagtcttt tgcagaaggg catctccgat gtatttttcg ttttgaagta tcttcttaac
    22321 tgattctggt cgccatcttg gttttcccgc tgctgttaaa ataccatcct tttcaagggc
    22381 tcgaccaatg cccactagac tctgaccctc aaggtattct cggtagatgc gtttgataat
    22441 ctcagcttct tcggggacaa tagttaaatt tccatcttca tctttcgtgt agcccataaa
    22501 tcgcttatgg ttgacctgca cctttccttg ttggtatcgg tactgtagcc caagcttaac
    22561 gttttgtgaa aggctctggc tttcctgctg tgccaaagat gccataatag tcagcaaaac
    22621 ctcacctttg gcatccgtgg tgttgatgtt ctctttctca aaataaactg atatgttctt
    22681 atccttgagc tgtctaatgt attgaaggca gtctagggtg ttacgcgcaa atcggctgat
    22741 ggattttgta ataaccatgt cgatgttacc gtccatacac tctgcaatca tgcgattaaa
    22801 ttcgtcacgc tttttagtgt tcgtaccaga gataccatca tctgcaaaga tgccagcaaa
    22861 ctcccattca ttatttttct ttataaactc tgtatagtgt gagacctgaa cctcatagct
    22921 agaattttgt tcttctgttt ctgtagaaac acggcaatag gcagcaacac gaagtttctt
    22981 tatcttttct tttgcggctg tacttcctac tcttttacga gcaggaataa ccattatatt
    23041 tttctctgtc actttattcc tcgctttcta tcagactgta taagtattct gctcgttcaa
    23101 aaggatccac tggcatctta ttatctgcct ttttcatttt gaatcgttct ttgggagggg
    23161 gagaggtgaa agcggcaagc tctaccactc gtcctaaatc ctttgcacgt ttatctctaa
    23221 cttcttcagc tttatcaaat atctctttat caataattgc tggatacgta tcatttccaa
    23281 ggtagttgac gtttttcaaa atgcgcccca tcacagaatg tgtcttttca atacctgcct
    23341 gttcgccagc cactgtaagg gatagtcctg atatgtattt ctcaaagaat acctttactt
    23401 gacctgctgc cttttcatcg acagtaacca ctccatcttg aattttgtat ccatatggaa
    23461 tatatgccat ttatctcacc accttttctt tcagggaaag accgcatttc aaattgaatg
    23521 tcagctcatc cctggaattt acaatgatgt tcactacaaa ttcttcaaat agttcttccg
    23581 tgtagtcacc attaaaatta tctgctgaca cataattaat gaggtccttt atctcgtttg
    23641 ctcgcaaaac cccactcgca gagttcgtta ccaggtttgt tttttcggta gtaagatttt
    23701 taatctcact atctaaaaca tttcgttcct gattaaaaag agcaggttct aggaaacctt
    23761 tggacatcag tgcaataagg gtattgcgtt cttccaatag ttgctccatt agcttatcaa
    23821 tagcgtccat tctttcacgg tcgctttctt catcgatttg gctaactgac ttgaaaagtg
    23881 gttctaggat tagcttatga ctgaaagcaa gcttattcat catggttgtc aatgtggctt
    23941 tgatttcccc atctcgcaaa aacaacatgg agcaactttc tttatcttcg atactatctc
    24001 aacatgtgtc gtggataagg taagtatgta aaatggtatg tggaacatag tgatttgctg
    24061 taaatgattt gctaactact ttagttcttt atacaaagta taaatcggat attttattat
    24121 tttttctttt atatcttctg agattaggtc aaagtatttg tccgctaaat cagaaagggg
    24181 ttcttttttc atcacctaat gggtgatgaa gcagaatact ttaaagacta ttaaatcaat
    24241 gttaggaaag actattagta aaactatgaa ttattcagga aaaaaggttc ttttttaaag
    24301 ttttctattg cttcctggcg ttgataaatg agatataaag tcggtgtttg tacacgtcct
    24361 aatgaaaatg taccttgtac gcctttttgt tgtaaattca aggtatataa agggcttgcg
    24421 ttcatgccga tcaaccaatc ggcaatttgg cgtgtttgcg cttcttgata aaagggatag
    24481 taattcattc ctggttgcaa attttgaaaa ccgcttcgga tcacatcttt ttctaagcta
    24541 ttgatccata atcttttata cgttttatct ttagaaaagg catttgcttt atggataatc
    24601 gaccaggcga tattttcacc ttctctgtcg ctatctgttg cgacaataat tgtatttgcc
    24661 tttttgagaa gttcagcaac aattttaaac tgctttccct tatcttttgc aacttcaaaa
    24721 tcgtatcgat caggaaaaat cggcaaagat tcaagtttcc agttctgcca cttttcgtta
    24781 taatgacctg gttctgctaa ttcgactaaa tgcccaaaac caaaggtgat aaacgtttca
    24841 tctgtaaata gtgggtcttt gatctcaaaa taaccgtctt ttttggtgct ttgttttaaa
    24901 gcacttgcgt aggctaatgc ctggcttggt ttttcagcta aaataaccgt actcattaac
    24961 tatccctctt ttcattgttt ttttctttga tctactgtca cgttgtatct tgatcgatac
    25021 cttctaaacg ttcggcgatt aattccagtt tgttcttcaa cttctttatc ggaacaacca
    25081 ttcaaaaata aatcgaaagc gtgttgtaaa cgtggatcat tttctttgaa tttaggttgt
    25141 cgccctttga attttccttt tttcttagca atttcaattc cttgggcttg gcgttcttta
    25201 attcgtttgc gttcagattc cgcttggtac ttatacaatt cggttctgtt gcaaagtttt
    25261 aaataaagaa taaaatccct tacggtatct atgatttaag ctgggattcc caataatacc
    25321 ttgatttcag tacagaccga aaacccgaag agagtgcctt cttttcgggt tttcttatat
    25381 aatcctcgaa tggcttccat gcctttaatc gtggtagagg cagtgcgtaa acttcgatag
    25441 aatttattgc gtctctttac tggacgatgg tcttgttcaa tcaaattatt caggtattta
    25501 atggtacgat gttctgtccc ttgataaaag ccgtattctt ttagtttctt aaaggcactt
    25561 gtaatagagg gggctttatc tgtgactaca accttcggtt catcaaactg cttcactaac
    25621 cgcttaagaa aagcataggc tgcttgtgtg tcccgttttt tacgtaacca aatatccaag
    25681 gttaaaccat ctgcatcgat ggctcgatac aaataatgcc attttccttt aattttgatg
    25741 tacgtttcat ccattttcca tgaataaaag gattttttat ttttcttttt ccaaatttga
    25801 tagagtagtt tgccatattc ttgcacccaa cgataaatcg tcgtatgaga aacgttaatg
    25861 ccacgatcat ataagatttc ttgaacttca cgatagctaa ggttataacg aagatagtag
    25921 cccacggcta caataatcac atcctgctga aattgctttc ctttaaaagg attcatcgtc
    25981 attcctcctg ctatcttttt ctattattct accttatttg atagtagatt taaaactttg
    26041 caacagaacc gttcgtcaca tcttcgatca atttctctta cgattttctc atccacattt
    26101 cttattctta cttccatatt aattcctcca atttaaaaag gatagcgaaa aggagcctat
    26161 cctttttgct atcctactac cctcctttta ctatccttca ctatcctttc actatcctat
    26221 ttttaaatat tttgttccca catttatttt tgagaaacgt aataggcaca gcctattgga
    26281 acactttttt taaaaagtgt tcccacgttt ccttatgctc tttacaaata aaggctttta
    26341 gagacgttct ggaattttag attccttgaa ttgttcccat tcatcaatca attggctata
    26401 agtagccatt aatttttttc ttgctcttgt tgctttcgaa tcaacaaaaa atcagtttga
    26461 ttcgttaatt ctaaatattc tgttcggtat tcaatgttca tcgtacccgt tttactacat
    26521 agtaactgat tatgacgttc tttcactttg aataactgct ccttctttaa ggtttttaac
    26581 tccatgccaa ctataagcac aatcctgtat agaggaatca ttttcaaacg att
//
