LOCUS       NZ_LR135375            22271 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Enterococcus faecium isolate E8172 plasmid 4.
ACCESSION   NZ_LR135375
VERSION     NZ_LR135375.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA4885602
            Assembly: GCF_900639555.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22271)
  AUTHORS   Arredondo-Alonso,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) UNIVERSITY MEDICAL CENTER UTRECHT,
            Heidelberglaan 100, 3584 CX Utrecht, Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 03:05:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,937
            CDSs (total)                      :: 2,846
            Genes (coding)                    :: 2,748
            CDSs (with protein)               :: 2,748
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 98
            CDSs (without protein)            :: 98
            Pseudo Genes (ambiguous residues) :: 0 of 98
            Pseudo Genes (frameshifted)       :: 31 of 98
            Pseudo Genes (incomplete)         :: 59 of 98
            Pseudo Genes (internal stop)      :: 31 of 98
            Pseudo Genes (multiple problems)  :: 17 of 98
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR135375.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..22271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /isolate="E8172"
                     /db_xref="taxon:1352"
                     /plasmid="4"
     gene            complement(123..1295)
                     /locus_tag="EQB36_RS15055"
     CDS             complement(123..1295)
                     /locus_tag="EQB36_RS15055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="WP_000195429.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
                     /name="IS256-like element IS256 family transposase"
     gene            complement(1445..2125)
                     /locus_tag="EQB36_RS15060"
     CDS             complement(1445..2125)
                     /locus_tag="EQB36_RS15060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<2200..2805)
                     /locus_tag="EQB36_RS15065"
                     /pseudo=""
     CDS             complement(<2200..2805)
                     /locus_tag="EQB36_RS15065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358225.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            2988..3947
                     /locus_tag="EQB36_RS15070"
     CDS             2988..3947
                     /locus_tag="EQB36_RS15070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222573.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHCLNRSRQTIHKVYLFF
                     KQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIRCS
                     ARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFKSITF
                     DCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDESF
                     IQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
                     /name="IS30 family transposase"
     gene            complement(3971..4267)
                     /locus_tag="EQB36_RS15075"
     CDS             complement(3971..4267)
                     /locus_tag="EQB36_RS15075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(4402..5895)
                     /locus_tag="EQB36_RS15080"
     CDS             complement(4402..5895)
                     /locus_tag="EQB36_RS15080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            6507..7460
                     /locus_tag="EQB36_RS15085"
     CDS             6507..7460
                     /locus_tag="EQB36_RS15085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            7432..7707
                     /gene="prgO"
                     /locus_tag="EQB36_RS15090"
     CDS             7432..7707
                     /gene="prgO"
                     /locus_tag="EQB36_RS15090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            7900..8154
                     /locus_tag="EQB36_RS15095"
     CDS             7900..8154
                     /locus_tag="EQB36_RS15095"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000199136.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYLP
                     DQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
                     /name="transposase"
     gene            8560..9722
                     /locus_tag="EQB36_RS15105"
     CDS             join(8560..8836,8836..9722)
                     /locus_tag="EQB36_RS15105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_086953888.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKWV
                     KQFKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANKHL
                     YPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSKRGI
                     QISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLT
                     YVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFHTDRGK
                     EFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLEL
                     FDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
                     /name="IS3 family transposase"
     gene            9898..10395
                     /locus_tag="EQB36_RS15110"
     CDS             9898..10395
                     /locus_tag="EQB36_RS15110"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_228780308.1"
                     /translation="MCEKWAADITYIPTKKNGWCYLSSIMDLHTKRIISYTFSKRMTVD
                     CVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGI
                     ESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEK
                     MA"
                     /name="IS3 family transposase"
     gene            complement(10868..11440)
                     /locus_tag="EQB36_RS15120"
     CDS             complement(10868..11440)
                     /locus_tag="EQB36_RS15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(11456..12061)
                     /locus_tag="EQB36_RS15125"
     CDS             complement(11456..12061)
                     /locus_tag="EQB36_RS15125"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            complement(12259..12939)
                     /locus_tag="EQB36_RS15130"
     CDS             complement(12259..12939)
                     /locus_tag="EQB36_RS15130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            13277..13672
                     /locus_tag="EQB36_RS15140"
     CDS             13277..13672
                     /locus_tag="EQB36_RS15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002304891.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIVD
                     YFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKKKE
                     YNYIVKAKVSKRFIFNPKLEIYSVVIE"
                     /name="hypothetical protein"
     gene            13997..14614
                     /locus_tag="EQB36_RS15145"
     CDS             13997..14614
                     /locus_tag="EQB36_RS15145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001224538.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFKR
                     PEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTASY
                     KQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPPEFP
                     AIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
                     /name="recombinase family protein"
     gene            14655..14954
                     /locus_tag="EQB36_RS15150"
     CDS             14655..14954
                     /locus_tag="EQB36_RS15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="WP_000366408.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFLV
                     CGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
                     /name="BRCT domain-containing protein"
     gene            14988..>15068
                     /locus_tag="EQB36_RS15900"
                     /pseudo=""
     CDS             14988..>15068
                     /locus_tag="EQB36_RS15900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /name="transcriptional regulator"
     gene            complement(<15063..15314)
                     /locus_tag="EQB36_RS15160"
                     /pseudo=""
     CDS             complement(<15063..15314)
                     /locus_tag="EQB36_RS15160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328003.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin epsilon"
                     /name="antitoxin epsilon"
     gene            16163..17188
                     /locus_tag="EQB36_RS15165"
     CDS             16163..17188
                     /locus_tag="EQB36_RS15165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271442.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_230204054.1"
                     /translation="MSIIPEKQNNQKQVLTLNELSKRKVVEHNSLITSIAKMEKTSLKM
                     FELAVSCINTEEPPEDNTVLLSKADLFAFFNVSDNDKHSRFKQAVETMQKQAFFKIQEQ
                     KDKGFKFINIVPIPYVEWNDYNDEVTIRFDQAIMPYLINLKKNFTQHALSDLAELNSKY
                     SIILYRWLSMHYNQYEHYSVKGGRRADQVESYRNPSITVKELRLMTDTVKEYQHFPHFE
                     NWILKKPLEEITKYTSFNVTYDKIKKGRSIDSIVFHIEKKRRADDNSYKLEDKDYQSGK
                     EEKSRNEADLLKQAMESKYTRLLIENFLLSPLEMTDTALMAGLQKNVYPLYDEVNYSPL
                     S"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(17325..18473)
                     /gene="tnpB"
                     /locus_tag="EQB36_RS15170"
     CDS             complement(17325..18473)
                     /gene="tnpB"
                     /locus_tag="EQB36_RS15170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="WP_002287525.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYEE
                     VKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRFKS
                     KKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKY
                     YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLS
                     RRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKD
                     GKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
                     /name="tnpB"
     gene            complement(18490..18894)
                     /gene="tnpA"
                     /locus_tag="EQB36_RS15175"
     CDS             complement(18490..18894)
                     /gene="tnpA"
                     /locus_tag="EQB36_RS15175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="WP_002287522.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMF
                     WSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
                     /name="tnpA"
     gene            <19056..19253
                     /locus_tag="EQB36_RS15180"
                     /pseudo=""
     CDS             <19056..19253
                     /locus_tag="EQB36_RS15180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB protein"
                     /name="RepB protein"
     gene            19246..19878
                     /locus_tag="EQB36_RS15185"
     CDS             19246..19878
                     /locus_tag="EQB36_RS15185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_016628117.1"
                     /translation="MSENLKTIKELADELGVSKKKIHYQVSKLDSNLIQRLDGTIYLNN
                     AAIKVIKGNIGYVPKTKLDSVGVQNRQYLDTKLDTVNTSLIDEKNERINYLKEQIKNKD
                     NQISVKDEQIKSLVDVQKQTQNLLDQQQRLALQDKKLLEEYKAENDSLKALKMPSQETE
                     FKHLDNQYKDEVNALKEHLETLQEQIKDQKRIEEQEKPRKWWELWRK"
                     /name="hypothetical protein"
     gene            <19932..20375
                     /locus_tag="EQB36_RS15190"
                     /pseudo=""
     CDS             <19932..20375
                     /locus_tag="EQB36_RS15190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /name="restriction endonuclease subunit S"
     gene            20432..20824
                     /locus_tag="EQB36_RS15195"
     CDS             20432..20824
                     /locus_tag="EQB36_RS15195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000393259.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYT
                     LLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACH
                     VYEKLGGKNDYKDEIVYVYDYEKGDK"
                     /name="GNAT family N-acetyltransferase"
     gene            20825..22264
                     /locus_tag="EQB36_RS15200"
     CDS             20825..22264
                     /locus_tag="EQB36_RS15200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="WP_001028141.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
     ARG             20826..22261
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="99.79"
                     /coverage="100.0"
     ARG             20826..22264
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.79"
                     /coverage="100.0"
     Typing          complement(4403..5895)
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          16211..17164
                     /name="rep_cluster_556"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.644"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 atatatgaaa agctattata aaagacatta gtattaaata gtttaaaaaa atgaaaaata
       61 ataaaggaag tgagtcaagt ccagactcct gtgtaaaatg ctatacaatg tttttaccat
      121 ttctacttat caaaattgat gtattttctt gaagaataaa tccattcatc atgtaggtcc
      181 ataagaacgg ctccaattaa gcgattggct gatgtttgat tggggaagat gcgaataatc
      241 ttttctcttc tgcgtacttc ttgattcagt cgttcaatta gattggtact ctttagtcga
      301 ttgtgggaat ttccttgtac ggtatattga aaggcgtctt cgaatccatc atccaatgat
      361 gcgcaagctt ttgaatattt tggttgatcg atataatcat gaatcaatcg atttttagcc
      421 tcacgcgcta agttaatatc tgtgaactta aaaattcctt taacagcttc tctgaaagat
      481 tttgaatttt ttttaggaat ggtggtaaag atatttctta ggaagtgaac ttggcatctt
      541 tgccaactta cgttggtgaa ggattttcta atggcagaga ctaatccttt gtgcgcatca
      601 gaaataacga gttccgtacc ttgtaaaccg cgttctttta ggtattcaaa aaatgttgtc
      661 caggtctctt cgctttcgcc actttgaatc atgaagccga taatttcacg gtcgccatct
      721 ttggttattc caatcgctat atgacagctt tttgagagta ctcgattttc ttctcgtact
      781 tttatataga gtacatcggt cattaagtaa ggataatttt tttctgataa taaacgattc
      841 tgccactcgt taaccatagg ttctagctgt tctgttaagc tagaaacgaa ggacttagag
      901 acggatttac cacaaagttc ttccacaatt tttgatactt tacgagttga aacgcctgat
      961 acatacattt ccaacattga agccatgagg gctttttcgt ttcgttgata acgttcaaac
     1021 actgtgggtg aaaaatggcc atcacgtgtt ctgggtactt ttaattctag cgtgcctaca
     1081 cgtgtcgtaa agctgcgctc ataatagcca tttcgttgac tttgtcggtt ttctgttcgt
     1141 tcatattctt ttgcttgaat atattctgtt cgttgatttt ccattagttg attaaatacc
     1201 gttgttaaaa tatttttaga aacgtcatcc tttacagaat attcaataat gctttgaatc
     1261 tcttcgcttt tcagtgtaaa atgtacttgg gtcatgtaaa agtcctcctg ggtatgtttt
     1321 tgtcgttaaa aacattgtac cgtaaaagga ctgttatatg gcctttttac ttttacacaa
     1381 ttatacggac ggttctgttg caaagtttta aataaagaat aaaatccctt acggtatcta
     1441 tgatttaagc tgggattccc aataatacct tgatttcagt acagaccgaa aacccgaaga
     1501 gagtgccttc ttttcgggtt ttcttatata atcctcgaat ggcttccatg cctttaatcg
     1561 tggtagaggc agtgcgtaaa cttcgataga atttattgcg tctctttact ggacgatggt
     1621 cttgttcaat caaattattc aggtatttaa tggtacgatg ttctgtccct tgataaaagc
     1681 cgtattcttt tagtttctta aaggcacttg taatagaggg ggctttatct gtgactacaa
     1741 ccttcggttc atcaaactgc ttcactaacc gcttaagaaa agcataggct gcttgtgtgt
     1801 cccgtttttt acgtaaccaa atatccaagg ttaaaccatc tgcatcgatg gctcgataca
     1861 aataatgcca ttttccttta attttgatgt acgtttcatc cattttccat gaataaaagg
     1921 attttttatt tttctttttc caaatttgat agagtagttt gccatattct tgcacccaac
     1981 gataaatcgt cgtatgagaa acgttaatgc cacgatcata taagatttct tgaacttcac
     2041 gatagctaag gttataacga agatagtagc ccacggctac aataatcaca tcctgctgaa
     2101 attgctttcc tttaaaatga ttcatcgtca ttcctcctgc tatctttttc tattattcta
     2161 ccttatttga tagtagattt aaaactttgc aacagaaccg atcaattcgt catatcttcc
     2221 aaaatcaaca ttgtactcat aaccaagaag tgtcggaatc aggtcaattt caatttcttt
     2281 ttcaattgaa cgtttaataa gtttcgtgga tacatacccg acaaaaaaga gaataatacc
     2341 cacttcaaac aaatacatgt gtccatttac aaagtgaata aacgtcaata aaaaatcctt
     2401 cactcctttt gttgttcttc cagattgttc aatttgtttt attaaagtcg ctagaattgc
     2461 atttacaaca attaaatcga ataggctttt gaaaagtttt cctgctgtta atttttgcct
     2521 ggtaaattgc atgactaatt gagtaaaaat agacaatagc atgacaaaaa tcaacgtcat
     2581 tagcactgta aaaatgtctg atgctgcaat cctattggga tcatttatca agtaataagc
     2641 cgttccaaat actccaatcg agtaaacggt taaatcaaga ataagtcgtg ccccgtaact
     2701 acaaagtttt cctaatggcc ataattgcaa tacccaaaat ttctttcgtt tgctatttct
     2761 tttcagagga agccaggtgt gttcaatcca gtcgtccgat ttcatttcga tttcttccct
     2821 aaattctttc ctttaacgtt ttcctttgct actttagcag cgataggttg ctcaatgaac
     2881 caatttttta agtacgccga ttgtaaaatt aagctagaca actaaaaaag tcatttgtgc
     2941 tacactcaaa atagttccgt ccaaagaatt ataaggagtg agtacaaatg acctataccc
     3001 atcttacaac ggatgaactt gtaatgatag agtcttattt caaaataaat caatctgttg
     3061 cgaaaactgc gcattgcttg aatcgttcaa gacaaacgat ccataaagta tacctgttct
     3121 tcaagcaagg aaaatcagcc ttagagtact atcaacagta taagaaaaac aaatcaaact
     3181 gtggtagacg cccgcttgtt ttacctgagg aacaatcaga atatattcaa agaaaggttg
     3241 ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc gtttcctatt cgttgttctg
     3301 ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttaa tccttctgac ttaccgatga
     3361 aaggcaagcg taaaccaaat ggacatcaag aaagacgtgg aaaacaagct ttccgtcgct
     3421 ctattcatga acgtgaaaaa gattatagcc aattctcaaa tgagtttggt caccttgaag
     3481 gtgacactat cgtaggtttg aaacataaaa gtgctgtaat taccttagtt gagcgattat
     3541 caaaagttat catcacattg aaaccgtgtg gtagacaagc gattgatatt gaaaacaaat
     3601 taaatcattg gtttgaatct gtaccgaaaa atctattcaa atccatcact tttgattgtg
     3661 gaaaggaatt ttcaaattgg aaacagatca gtaatgccaa tgatattgcc atttatttcg
     3721 ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga ttgttacgta
     3781 gagatggttt attgaaatct atggatttca attcagtaga tgaatctttt attcaatctg
     3841 tcgcatcgaa acgaaataat attcctagaa aatcactgaa ttatcgaaca cctttggaag
     3901 tatttttgag ttacgtaagt attgatgatt tgtctaactt aatttgacaa ttaagagtaa
     3961 ataaaaacta ctactggata tacttcttcc tttttcttaa ctcgttagct attttatact
     4021 caatatactc ctgctctaac acacacaaac aatcatatac ctgatccata gtctccccag
     4081 aagctaagga caacccatga agaaactcaa tcggcaaaga agcaactgtt ttttccctgg
     4141 taacccaaga agacaaagtc ccctgcttaa aaccataaag ctcacagaac acttccacag
     4201 ataatcccaa acgaccaatg ataaacacat taacaggatg tgaatagaca taatttttta
     4261 acgacataca acttcctcca tgatacataa gactgcatac gcagttataa gtataccacc
     4321 tacacgtagc taggcaaagg gagcaacacc tacagaagta tcatagatat attgtataag
     4381 gcaatttgca ccttttattt ttcaacctgt atctacttca aaaagattca cttctttaag
     4441 agggttcaag ggggttgata attgtctaaa tgtctcttct actaagctct cgttgagtcc
     4501 aaatacctct gtgatccttg ttgaataatc tagtctcttt tctttactta gttgaataac
     4561 cctcgcgaac aacgttttga ctgaagcaat gatcattccg ccatttcttc ctcgtgttac
     4621 cttgtagaag actttattct cctctcgtaa ctcatttaag atcttatcaa gtgttcgctt
     4681 gggcatcgtt agttgtgaag ccaattcttt ttttgacagg ttcaaataag gctcactagc
     4741 aagacttttt tcgcttagat aagccaatag atcttctttc cattcatttt tatgactata
     4801 ttttctttga tctcgtggct ttttaaattt ccaccagcca cgtcgttgaa tgaacagatc
     4861 attatttttt aaggttggtg aaacccattg ctggcacaat tcaataatga attctctgct
     4921 tgctgcttga taattaccag aataagcact acgtacaatc tttactaatt ctgcttcaga
     4981 tagcggttcc tgtaaccgtt cgttgaatgt gaacatattg tattcgcaag tatccaatgc
     5041 ataacctgaa gagtaataag ctaaagaaag cgtgaaaatc acattatttc gaccaagacg
     5101 tccttctccg ccgacgatgt ttgctttatg aagtaacata tcgaaccacg gttcatctac
     5161 ttgacgaatt tcttttttct caggaaagac aattagtttt cgttctcgat cttcttttgt
     5221 tttttgatct gattcaagct tcatcgacca ttgaatccag tcagcaaaag aatactgata
     5281 gttcatttct ttaaaaacaa tattattttc ttgtgggaat cgagcaattc cgaagtggtt
     5341 acatcctaga tccactccgg acaatttttc agccaactgt agacgaattg tttttgaaat
     5401 tttttttgct acatcgatca ccttgaaatt gcttttcttt gtgacatagc ctggtgtctt
     5461 tagtacaaaa taaacttgat aaccatgatc tgattctaaa attagcgttg gcatgtagcc
     5521 cacttgatct aaacaggcta aaataatttc gccttgatgg ttctcttttg aatcgatatc
     5581 aactacaaat gtgttgattt gacttaagtt tttctcagaa tgacctttaa ccactgttcg
     5641 ataatcatcc gcataagtac caaagcgata ggtattaggt gtccaatgcg ttagtttctt
     5701 ttcgttctct aaaatagctt cttccgaagt aatgaccata ccacgcccaa cattcattaa
     5761 ttgcttgcta cggtacgcaa agatagcacc actcctactg gaatcaatat gacctgcagg
     5821 tttcatggtg ctgtttcgat atttgtatgt acgtaagccg tttttaagaa tagctgaata
     5881 aatttcgctc aacatcgatt gtaacgtcct ttctcaaaca aaaagagaac acagtttagc
     5941 tttaatctca gccatagtat gtgttctctc ttcagtgttt aagaatattt aatttaagta
     6001 cactaaataa acgttcttct gttgagttgc tcgccttttt ttggtagaat aaaggcaatc
     6061 ggaaaaggta tccgatcaac ttttaatata agtagttggt agctacttac atattcttga
     6121 gacgagcgtg aacacatgtc ctaaccatgt gattcagaaa taattgattc tgctaaaatc
     6181 aattatttcc gtctcttttt tttatgtaat ttttctgttt aaagagtacc actgcttttg
     6241 ctactttgta aatagtgaat tatctgtggt ttctatagaa ttaagtttac ctcttttcac
     6301 tctaaattgt caacgcaaaa cgcacaaata tattttgaca ttttgaatat atctgatata
     6361 ctgaatatag caaatatatt tagtatatcc actatattcc ttataaagtc tgaattctta
     6421 tcaatttgga gtatattaga tatatcgaat atattaagta tatgaagtat actaaatata
     6481 tttagtatag gaaattggag ggaactatgg aaaacttacg gactgcattt aaaacatcag
     6541 ataaactagg aaaagttgta atgcttacag gtagaaaagg cggcattggt aagactacag
     6601 acaatgattt attagcgatt gtttctagtc aactttttga aaaagacgtg ttgctaattg
     6661 attatgacca acaaagaaat actacttcca acattggatc aacgtatcaa attactagct
     6721 ttgatcgatc catgtctgca gcaatcaaaa aaggggactg ggtttcaggt attactcaag
     6781 taagtccaca tttatatatt atggctggct ctcctggatc tgaagaactt aatgaatact
     6841 tgtccgaaaa atatcctgat cgtcgtaaga gatcattggc cttcattaaa cctttagaag
     6901 aattgagaaa aaatttcgat tatatcttta tcgactgccc accatcaaca gataatgtgg
     6961 ttcgtgcatt cttaactgct gcagattata ttattgcaat gcaagaatta aaacggtacg
     7021 caatggaagg aacagaagat tttattaata aagttttagt tccgattgtc acgaattttg
     7081 aagagtctca tcttcaaatc attggaattt tgcctgttct tttctcagtg cgacgttcct
     7141 ctcaacacgc aaactatcaa aaaacaattg ataagtatgg tgaatcaaac atttttaaaa
     7201 gcattgttaa aggctcggat cggttagaaa tgtatggtga gaatggtatc caattaaatg
     7261 attatgtaga tcgaagatgg tgggctattt ttgcagacat ctttacagaa ttagaagaaa
     7321 gaattgaata ctatgaacaa catggtgata ttgaaggatt tgattataca cctaaatatg
     7381 ctgactcaat ggccaatcat atcctacctc ttggaaagga gattaaacta aatggcatta
     7441 ttaccaacga acaaagataa gaagaaaatt ggtgctgaag atatttcaat taaagatgat
     7501 attaatgtcg agttagggga acgaaagtac actgcgaaag aaagaaaacc agttcaagta
     7561 gatcctcccg tactaaaaac cattcgggat cttagttatg caaaagatat tcctatgtat
     7621 gaaatagtca aacttgcaat ggacgcctat gttgatactt taaacgacga ggaacggatt
     7681 atatataata gacgatcaaa agattaaaat atagtaagta tactagatat agtaaatata
     7741 tttagtatac ttactatatt tttagcttta ttaatcctaa tccttcaaaa tatgtgtatt
     7801 gtttgggggt atacaacatt tggtgttagt atcaaatctt agacagcttt tcgtagagac
     7861 aagaataaat taaacttatc tacgagagga tgaattttta tgacccgata tgaagaaaat
     7921 tttaaacaaa tgattgttga actgaatcaa actggacgtt ctgttcgagg gttagcgaaa
     7981 gaatatggct tatctgaagc aacgatttac aaatggaaga atttatattt acctgatcag
     8041 tccacaggac tgactggaaa agaagtagct gaactgagaa aagaaaatgc tcgtttaaat
     8101 gaggaacttg aaatcttaaa aaaagccgca gccatattct ctcggaaaac ctaaattcgc
     8161 ttgttcaatt tattgaaaaa tggtgtaagg attacactgt ttctttgttg tgtcggttat
     8221 tagaaatccc tagaagtgtc tattattttt ataagaataa accgttgaca gctacagaaa
     8281 tcagaaataa taagttgaaa aagaagattt caacaatttt ttttacgaat aaacaacgct
     8341 atggtgccac aaagatccat caagttttat taaaagaagg gatttcagta tctcttaaac
     8401 atgtccaaaa gctaatgaaa caattaaatt taaggtcgat tgtagttaaa aaatatagac
     8461 ctcaaaggtc taataaaccg atcatggata ggctacaatt aactagacag aaaaattaag
     8521 gtgtgtagac tagaagaaaa cataccagga ggaattttta tgtctaagag aacacgaaga
     8581 actttttcac aagaattcaa gcaacaaatc gtcaatcttt acttagctgg aaagccacgt
     8641 gtagaaatca ttcgagaata tgaactaacg gcttcagcat ttgacaaatg ggtaaagcaa
     8701 tttaaaacga gtggttcatt caaagaaaaa gataatctta cgcctgaaca aaaagaattg
     8761 ttagaactac gtaaaagaaa ccagcaatta gaaatggaaa atgatatttt aaagcaagca
     8821 gcgctgatat tcggacgaag agacaagtaa tcgatgcgaa taagcatctt taccctatat
     8881 cagcgatgtg cagaatatta ggtctatcac gtcagtccta ttattatcaa tcaaaaccaa
     8941 agaaagacga atcagaactt gaagaagtag tcgctgaaga atttatccgc agccgaaagg
     9001 cctacggctc aagaaaaata aaaaaagcct tatcaaaacg aggcattcag atcagccgac
     9061 gaaaaattag tagaatcatg aaaaatagag gattaaaatc gagctatact gttgcttatt
     9121 ttaaagtaca tcattctact tgcaatgaag ccaaaacgac aaacgtattg aatcgtaaat
     9181 tcttaagaga caacccatta gaagcgatcg taacagactt gacttatgta cgagtcggga
     9241 aaaaatggaa ttatgtctgt ttcattttgg atctgttcaa tcgagaaatt ctcggctatt
     9301 cttgtggaga acataaagat gccgttctag taaaaaaagc atttagccgt atcaaacaac
     9361 ctctgacaga ggttgagatt tttcatactg atcgtggaaa agagtttgat aaccaagcta
     9421 ttgatgaatt attaacaact tttgacatca atcgatcatt gagtcataaa ggctgtcctt
     9481 ttgataatgc cgtagctgaa tcaacttata agtcgttgaa agtagaattt gtctatcaat
     9541 acacatttga aaccttacaa caattggatt tggagttatt tgactatgtc aattggtgga
     9601 accaccttcg gttgcacggt acacttggct acgagacacc ggttggttac cgtaaccaga
     9661 gattggcgca gcgaatcctt gataatgagc tcggatgtgc taacgctagc gaggcagtct
     9721 aactttaact gttagctcct gccgaagatc gtcacatccg aggaggctca ttgtcaagga
     9781 caatcggaat agcatacgga aagaagttct gcaccttata aaatttgtca aaaaaactgt
     9841 tgccattcca tcatttcaaa agagaatctc ttaaatcagg acttttctac tgaaacgatc
     9901 tgtgagaaat gggcagctga cattacgtac attcctacta agaaaaatgg ttggtgttac
     9961 ttatcttcaa tcatggattt acacacgaaa agaattatta gttatacatt ttcaaaacga
    10021 atgactgtgg attgtgtcat tcaaacattg aataaagcaa aaatacatta tcacattcca
    10081 gaaggaatga ttctacacac tgacttgggc agccaataca cagcaagaga agtggaacaa
    10141 tggcttaaaa ccaacaaaat aaggcattct tatagtagaa aaggaacacc ttatgataat
    10201 gctggaatcg aatctttcca tgcctcattg aaaaaagaag aagtctacac gactagctac
    10261 tcagattttg aagaagcaaa tcgagcgcta tttagctaca ttgaaggatt ttataaccga
    10321 aatcgaatcc atagctcgat tcactatcta accccacagg aatttgaaga attagcaaaa
    10381 gaaaaaatgg cttaaccgtc tctactaaaa tgtgtccaag atattgactc aaatccagta
    10441 atatcacaat aggaatgctg tttattatat tagcagcagt gctgattttt atgatagtta
    10501 tttggttctt aaatgaaaga tctaaagaca atcaacaccg tagggatatg gagataaaat
    10561 caatagagtc aatagattat ttatcgataa taacactaaa aaagccacgt tcctaaacgt
    10621 gacttacgct gaacgatatg tgttgtttgg tagacgaaca aatcgttcat tataaatata
    10681 tgatggtatc ctaatatagt aagcgtggct agcatacctt taattacttt accttttaca
    10741 gttaccatac acattttttg agcagaaatc aagtaaataa aaaaatatta tatttcacaa
    10801 catgctaata gactcatatc tagaacgcat taagtattta cctgtctggt tcgctgagac
    10861 ttctttttta actttcttca attttcttct ttattctaaa aagcgtactg cgactgaaac
    10921 cggttatagc ttcaacttcc ttatacgatt tacctgaagt aagcagttca tatgcgtgcc
    10981 tcttcttcgg tgtgattgtt gctttcggac gtccttctct gaaattagga ttattctttc
    11041 ttgcaaacat ttttccttct tgggtacgtt ccacaatcat atcacgttcc atttctgcta
    11101 cactcaacaa cgtccgtgtc accattcgcc ccatggacgt attttcaatc gttcctagat
    11161 tcaaaacctt gatcgttacg ttatcatcga gtaaaggttc aatgatctct aatgcttctc
    11221 tcgtgttacg agcaaatcga tcaagcttcg taacaactat ttcatctcca ggcttcagac
    11281 cagccaacag ctgattgaat tttggccgat cccgttttgt acccgtaaat ttttctgaaa
    11341 aaatattctt cttctctacg ccgttctcaa gcaactgttg aatttgttct tttgtacttt
    11401 gagaagcggt tgagacacgt gcatatccat atttcgtcat ttggtccacc tacttttaca
    11461 aatcatctat cgtatactca gaataccctt catagaaata gctgacatcg attcctttca
    11521 tatataactc gcgatcgtca attttatcag tcagagcatt ggaaattaga tagcgtattt
    11581 ccaaatcgtt tatgggactt cgctccattg cagaaagata gtctgcttta tcgattaagt
    11641 tccaatctac aactttttgc aattcttcct ttaaaatgag atccagccaa attctagtac
    11701 ttcggccatt tccttctcga aatgggtgag cgatattcat ctccacatat ttcttgataa
    11761 tctcttcaaa agaagtttgt ggcatctgat caatatgctg taacgaatgt tctaaataca
    11821 taactggtgc aaatcgaaaa tttccttttg caatattgac cgatcggatt tttccggcaa
    11881 aatcgtaaat atccgaaaat agaaattcat gaatttcaga taaaccttta aatgtaccaa
    11941 cttcgatttc atttattttt ccacaatcgt acaattcttt cgctttttgt ttactgagtt
    12001 tttcttcaac cttagccaac tcaacttgat tggttaatcc caatttattc tctaaaatca
    12061 tgcgaaatct ccttaacttt atgacataag tttatgaaac actctcaacc ccattatatc
    12121 gcgattttgt ttatgtgtca aaaactatta agtttctgac ccccgataga tttttcaagt
    12181 gtctctattt tgcacagtct agttggttct gttgcaaagt tttaaataaa gaataaaatc
    12241 ccttacggta tctatgattt aagctgggat tcccaataat accttgattt cagtacagac
    12301 cgaaaacccg aagagagtgc cttcttttcg ggttttctta tataatcctc gaatggcttc
    12361 catgccttta atcgtggtag aggcagtgcg taaacttcga tagaatttat tgcgtctctt
    12421 tactggacga tggtcttgtt caatcaaatt attcaggtat ttaatggtac gatgttctgt
    12481 cccttgataa aagccgtatt cttttagttt cttaaaggca cttgtaatag agggggcttt
    12541 atctgtgact acaaccttcg gttcatcaaa ctgcttcact aaccgcttaa gaaaagcata
    12601 ggctgcttgt gtgtcccgtt ttttacgtaa ccaaatatcc aaggttaaac catctgcatc
    12661 gatggctcga tacaaataat gccattttcc tttaattttg atgtacgttt catccatttt
    12721 ccatgaataa aaggattttt tatttttctt tttccaaatt tgatagagta gtttgccata
    12781 ttcttgcacc caacgataaa tcgtcgtatg agaaacgtta atgccacgat catataagat
    12841 ttcttgaact tcacgatagc taaggttata acgaagatag tagcccacgg ctacaataat
    12901 cacatcctgc tgaaattgct ttcctttaaa atgattcatc gtcattcctc ctgctatctt
    12961 tttctattat tctaccttat ttgatagtag atttaaaact ttgcaacaga accaaatgac
    13021 gaaacagttg atatcttagg tgtagggata atttcatttt tcattgataa aatagttaat
    13081 aattcacttg ggacagattt tacttatctt gattttattg gagatgaggg gaaagttgca
    13141 aatggatttt ctgaaaaaat tattcaattt caagaaaata gaagtaaact taattaagaa
    13201 tcgtttacta tttaaacagt gtccttttcc tttttaaata tatacgataa aataagtata
    13261 tgaattgtaa aaggacatga tgattatgga agaaatagaa tggaataatc tgactcaaaa
    13321 taataaaaat aattctggat gtggaattat ctttatgttt gttatagttt tgggaatagt
    13381 agtactttta ataactgtca agatagtaga ttactttgcg aatactcctg aagaacaaat
    13441 acagagaaaa cttcctgagt ttgaaagagt accaccttat gatccaagag ataattcatt
    13501 tcaagtaaaa aaattaaaag agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc
    13561 aagcgacttc aaagaaaaaa agaaagaata caattatatt gtaaaggcaa aagtatcaaa
    13621 aagatttatt tttaacccta aattagaaat atatagtgtt gtaatagaat aatagtgtta
    13681 aaaaaattgt aaaagttaaa gaagtcaaat tctgatgtga aaaataaaat ataccatgga
    13741 agacataaaa gaaaaactgg ataactagtt tatttaatgg cagaccgtta aggcctgcca
    13801 tttttatgta ttttagcgga ataaatataa tcatgcggga gtgtaaactt actgtttcaa
    13861 aaagtatact ttttgacatg ccttgatttt ctttgtttat gtatggcata ataaccacat
    13921 aatacaattt gaaacgtttc tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa
    13981 agggtagata aaaacgatga gaaaattttt ttatatccgg gtcagtagtt atgatcaatc
    14041 gatcgaacga caactgattt ccgcgaagga attaggaatc cctgaagaat atatatttgt
    14101 agaaaaagcc agcggcaaag attttaaacg ccctgaatat caattaatga aacggatgtt
    14161 tcgaaaagga gatttactct atctacaatc attagataga ctaggcagaa ataaacaaat
    14221 gattttagaa gaatggcgag aattaactaa ggaaaagcag attgatattt ctgtgttaga
    14281 catgcctctg ttagatactg ctagttacaa gcaactagat gggttagaga cgcttatctc
    14341 tgacttaatt ctgcaattac tcagctatat ggccgaagac gagcggaaac gaattaatag
    14401 ccggcaaaga gaaggcgtag aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa
    14461 aattgcttta cctcctgaat ttcctgcgat ctattctgac tggaaagcag gaaagataac
    14521 tgcagtctat gctatggatc aattgggcat gaaacgaaat accttttatc gacgggtgaa
    14581 agaatatgaa cataccttgc accacttttc ttgatagata taacagctat tagacgggaa
    14641 gggagagttt gaaaatggac ttaacgaatc aaagggtcgt ttttactgga acgctgcagc
    14701 aaatgacacg aacccaagcc atcggtttgg ttcactcttt aaacggccat tgtcaatcaa
    14761 gtgttacttc aaaaacaaat ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg
    14821 attctctcta tacaaaaaag gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga
    14881 ttaccatttt atcagaagtc gaattttatg cgttaattag tcaacagttg aaagaatggc
    14941 aacggtattt ataatcgtta gtaaaattta caaggaggaa aatttttatg aagcgaaaat
    15001 cttatgatcg ttggggcatt gaaataacta gttttaatcg aaatattgct tttcacgtgg
    15061 agtgtgatac tgtcggcgta tttttttatt gatcgtaaat agtcatgata ggcttctagt
    15121 tcttcaagag ataatttaaa taaattaatt tgattcatgt ctgataattg gtttagcaaa
    15181 tttgtttgta ggtttgtaga atcgctttta tcgagttcat tatttaaaac atagttcaac
    15241 atttttgagt gaatcgctga ttgaaattca ttgattatct caatttcaaa tgtttttctg
    15301 taatctaagg tcatgttgtt tgctcctttc tggtttcgct ttgctcaact aaacatttac
    15361 ttttaattaa acagacttcg ctagtttaat caaaaataaa cgtgcgaata aaaagcaaat
    15421 catttttaaa gatcataaaa tgcgttctaa ggcgttttat gatctttatg tgtaatttat
    15481 actctttact tttaaaaagc ctgtatcagc ttgatattag tgtttaaatt gattttaacc
    15541 taattttagg gtgcttactt ctttttgggt gcgctagttt attcaaaagg aatcctgtaa
    15601 ataaaaaagt aacatgcttc acaaagctct atttttagtt ttaagggggt ttttgttcta
    15661 agtctgcttt tgggttgtta gggcttgccc tgaccgtctg taagacgctt gattgcgtga
    15721 tatgagtatt tagctagtca aacagttaaa acagcttata tgagcaatta gagggaatcc
    15781 actaaattcc taaaagtggt tttgatcttt tcttttagcg agtgaacgaa gtgaacgctg
    15841 caagtaaaat gtgagcgtgg ttttcgctca ctcctttttt tgatgacttt gatcgttact
    15901 tttacatttt tgaaaaaaat aaaaaatagg cgaagcctat attacattta tcttatatat
    15961 tttaatcttt tgttcttttg cgtgaaaaaa aagccagtgt ttccagtcgt atgcagaatt
    16021 aaacagtcag aaaaaactgt ttatacagtc agaaaaaaat tgaataactg actgtatttt
    16081 gatagaataa aagcatagag aaatacccga ctaaaagtct ttctctatgc ctacttaaaa
    16141 ttactcacaa aggagtattt ctatgtctat tataccagaa aaacaaaaca atcaaaagca
    16201 ggtgctgacc ttgaatgaac tatcaaaacg taaagtggta gagcataaca gcttgattac
    16261 ctcaatcgct aaaatggaga aaacctcact caaaatgttt gagttagcgg tttcttgtat
    16321 caataccgaa gaaccgccag aagacaatac agttttactc tcaaaggctg accttttcgc
    16381 cttctttaac gtgtctgata atgataaaca cagtcgcttt aaacaagcgg tagaaaccat
    16441 gcaaaagcaa gcctttttca aaatccaaga gcaaaaagat aaaggcttca agtttattaa
    16501 tattgtccct atcccttatg tggagtggaa cgattataat gacgaagtca ctatccgttt
    16561 tgaccaagcg attatgcctt atttaatcaa tcttaaaaag aatttcacgc aacatgcttt
    16621 gtcagacctt gccgaactca atagcaagta cagcattatc ttgtatcgtt ggttgtctat
    16681 gcactacaat caatacgagc attacagcgt gaaaggcgga cggagagccg accaagtgga
    16741 aagctaccgc aatccctcaa tcacagtcaa agaattacga ctgatgactg atactgtcaa
    16801 ggagtaccaa catttccctc attttgagaa ttggatatta aaaaaaccat tggaagaaat
    16861 tactaagtac acgtctttta acgtgactta tgacaaaatc aaaaaaggac gttcgattga
    16921 ttctattgtt tttcatattg agaagaaacg ccgagcagac gataacagct ataagttaga
    16981 agataaagat tatcaatctg gcaaagagga aaaatcaaga aatgaagctg acttattaaa
    17041 acaggcaatg gaaagcaagt acacacgatt attgattgaa aactttctct tatcccctct
    17101 tgaaatgacg gacacggcac ttatggcagg tttgcaaaag aacgtctatc cgttgtatga
    17161 cgaggtgaac tactcaccac ttagctaaac ctgacggttc ttaacgcttg aagtgggagc
    17221 ttcttgggaa tagagcatac ttgatagcgt atttctttac taacagcggt gtctcttatt
    17281 taccaagcta tccccgtagt tcctacggtt cttgatgatt ggatctaagc caatcccata
    17341 gaatgtagtc ttagaccttc ggtcagaata ttgatactag cattgatatc acgatcatga
    17401 tgagtatgac aaacaggaca agtccattct cgaatttcaa gagatttctt gccatcttta
    17461 tgtccgcact ctgaacaaat ctgactagac ggaaaccatt tatctacttt gatgattttt
    17521 cgtccatacc agtcagcctt gtattgtaat ttagtcacaa actttgacca agaaacatca
    17581 gaaatacttt tagctaattt atgatttcgc aacatacctt ttgtgtttaa gtcttcaata
    17641 cagataatat cgtgattttt gatcatttct gtactcaact tattcagaaa atcagtacgt
    17701 tgattcatta ctttttcatg caatctagct actttgcgtt tttgtttttg ataattttta
    17761 gcttcaaata gattggtacc tttattttta gccaataaag cacgcctaga caatttgcgt
    17821 tgttcacgct ttagtttctt ttccattttg gacgtgaatt tattattatc aattttttgt
    17881 ccatcagaaa gaatcgcaaa gtccataata cctaagtcaa taccaattgt ggaattagtt
    17941 ttaggtaatt cgataatttc ttctttacac aacaaagaaa tatagtattt accgctagaa
    18001 tgacgtgata ttgtagcaga tttgataatc ccttttggtt gtctatgaag cttaattctt
    18061 actaatgact tcaatttagg aactttgatg aatttactat caatcaaagc aactgtacca
    18121 ttttgattat tcgttgtata actctgaaca ggatttttct tacttttgaa acgtggaaat
    18181 ccaacggatt tatcccgaaa aaaattcttg tatgctttat ctaaattaag ttgggcattg
    18241 gctaaagcaa ggctatcaat ttctttcaaa aacggaaatt ctttcttgta tttagctggt
    18301 gtcggaaaag tcattttttt agaagaatca tttttaactt cttcatacgc cttttttcgg
    18361 tcatcaagca ttagattgta gaccttacgg acacaaccaa aagatttggc aaagaagatt
    18421 tcttgttcct ctgttggata gattctgaat ttgtatgctt ttagttgttc cataaagttc
    18481 acctactttc tatttatgat tgtttccttg attttggata tacttcttaa tcacatcaat
    18541 tggtgcgcca ccagttgtca gaagacaaaa gcttttagac cagaacattt ctttccaaag
    18601 aaattgtttg actcttggaa agtcacgttt tatcaatctt gagctggcac ttttataggc
    18661 attgatgaat tttgtcaatt ctgttttagg ttgagctttg aacataatat gaacgtggtc
    18721 tttatcatga ttccactcca ctaaagtaat gtgatacgat tctgaaattc tttcaaaagt
    18781 agttttggca taatcagata tttcatcatc aatcacttgt ctacgatatt tcgttactaa
    18841 aacaaggtgg taataaagaa gaaatactga atgattattt gtatctaatt ccatgttata
    18901 tcaactcatt tcttgtatag actgattgta acatgggaca aaataaaaag gcaatacgcc
    18961 ttagttgtcg gtcttcgagt taccaacggt aaccctcata ccgaacggca ttcatcaccc
    19021 acctatagag gatgggcgac ttctgcctaa ttctgttaaa ggaattaaga ggattgaatg
    19081 gggtcaaaga ccatttaagc tatgtagcca gcaaacaaga agcttattca aaacgtaatg
    19141 tagccaagta ccttaaaaaa gccattgaac aatacctacc aactgtaaaa ttacaagacc
    19201 ttgaccaacc agaacgtgca agtgttcgag gtaaaggagc aagccatgag tgagaatcta
    19261 aaaacgatca aagagcttgc ggatgagttg ggtgtatcaa aaaagaaaat tcattatcaa
    19321 gtatctaaat tagatagtaa tttgatacaa agattagacg gtactatcta tcttaacaac
    19381 gctgctataa aagtgattaa agggaatatt ggatatgtcc ctaaaactaa attagatagt
    19441 gttggtgtcc aaaatagaca gtatttagat accaaattag acaccgtaaa tacaagttta
    19501 attgatgaaa aaaatgaacg aatcaattat ctaaaagagc aaataaagaa taaagataat
    19561 caaatatctg ttaaagacga acagataaaa agtttagtag acgtacaaaa acaaactcaa
    19621 aatcttttag atcagcaaca acgactagcc ttacaagata aaaagttgtt agaagaatac
    19681 aaagcagaaa atgacagctt aaaagctctc aaaatgccct cacaggaaac agaattcaaa
    19741 cacttagaca atcaatataa agatgaagtg aacgctctta aagagcattt ggaaactctg
    19801 caggagcaaa tcaaagatca aaaaaggata gaagaacaag aaaaaccaag aaaatggtgg
    19861 gaactatggc gaaaatagat gattcagtta aaaagaaagt tccagaattg cgatttaaag
    19921 gattcacgga tgaatgggaa gagcgtaagt taggagaatt atctaatatt gttggtggtg
    19981 gaacaccaag tacatcgaac cctgaatact gggacggtga tattgattgg tatgcaccag
    20041 ctgaaattgg agaacaaagt tatgttagta aaagtaaaaa gactattact gaactaggtc
    20101 taaagaagag ttcagctcga attttaccag taggaaccgt cttatttact tctcgtgctg
    20161 gtatcggaaa caccgctata ttagccaaag aagctacaac taatcaaggg tttcaatcaa
    20221 ttgttcctga tcaaaataaa cttgatagtt attttatttt ttcaagaact aatgagctca
    20281 agcgataagc caatcgctta attggagccg ttcttatgga cctacatgat gaatggattt
    20341 attcttcaag aaaatacatc aattttgata agtagaaatg gtaaaaacat tgtatagcat
    20401 tttacacagg agtctggact tgactgagtt tatggaagaa gttttaattg atgataatat
    20461 ggtttttgat attgataatt taaaaggatt tcttaatgat accagttcat ttgggtttat
    20521 agctaaagaa aataataaaa ttataggatt tgcatattgc tatacacttt taagacctga
    20581 tggaaaaaca atgttttatt tacactcaat aggaatgtta cctaactatc aagacaaagg
    20641 ttatggttca aaattattat cttttattaa ggaatattct aaagagattg gttgttctga
    20701 aatgttttta ataactgata aaggtaatcc tagagcttgc catgtatatg aaaaattagg
    20761 tggtaaaaat gattataaag atgaaatagt atatgtatat gattatgaaa aaggtgataa
    20821 ataaatgaat atagttgaaa atgaaatatg tataagaact ttaatagatg atgattttcc
    20881 tttgatgtta aaatggttaa ctgatgaaag agtattagaa ttttatgatg gtagagataa
    20941 aaaatataca ttagaatcat taaaaaaaca ttatacagag ccttgggaag atgaagtttt
    21001 tagagtaatt attgaatata acaatgttcc tattggatat ggacaaatat ataaaatgta
    21061 tgatgagtta tatactgatt atcattatcc aaaaactgat gagatagtct atggtatgga
    21121 tcaatttata ggagagccaa attattggag taaaggaatt ggtacaagat atattaaatt
    21181 gatttttgaa tttttgaaaa aagaaagaaa tgctaatgca gttattttag accctcataa
    21241 aaataatcca agagcaataa gggcatacca aaaatctggt tttagaatta ttgaagattt
    21301 gccagaacat gaattacacg agggcaaaaa agaagattgt tatttaatgg aatatagata
    21361 tgatgataat gccacaaatg ttaaggcaat gaaatattta attgagcatt actttgataa
    21421 tttcaaagta gatagtattg aaataatcgg tagtggttat gatagtgtgg catatttagt
    21481 taataatgaa tacattttta aaacaaaatt tagtactaat aagaaaaaag gttatgcaaa
    21541 agaaaaagca atatataatt ttttaaatac aaatttagaa actaatgtaa aaattcctaa
    21601 tattgaatat tcgtatatta gtgatgaatt atctatacta ggttataaag aaattaaagg
    21661 aactttttta acaccagaaa tttattctac tatgtcagaa gaagaacaaa atttgttaaa
    21721 acgagatatt gccagttttt taagacaaat gcacggttta gattatacag atattagtga
    21781 atgtactatt gataataaac aaaatgtatt agaagagtat atattgttgc gtgaaactat
    21841 ttataatgat ttaactgata tagaaaaaga ttatatagaa agttttatgg aaagactaaa
    21901 tgcaacaaca gtttttgagg gtaaaaagtg tttatgccat aatgatttta gttgtaatca
    21961 tctattgtta gatggcaata atagattaac tggaataatt gattttggag attctggaat
    22021 tatagatgaa tattgtgatt ttatatactt acttgaagat agtgaagaag aaataggaac
    22081 aaattttgga gaagatatat taagaatgta tggaaatata gatattgaga aagcaaaaga
    22141 atatcaagat atagttgaag aatattatcc tattgaaact attgtttatg gaattaaaaa
    22201 tattaaacag gaatttatcg aaaatggtag aaaagaaatt tataaaagga cttataaaga
    22261 ttgattatat a
//
