LOCUS       NZ_LR135311            27647 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Enterococcus faecium isolate E7240 plasmid 5.
ACCESSION   NZ_LR135311
VERSION     NZ_LR135311.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA4885079
            Assembly: GCF_900639485.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27647)
  AUTHORS   Arredondo-Alonso,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) UNIVERSITY MEDICAL CENTER UTRECHT,
            Heidelberglaan 100, 3584 CX Utrecht, Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 03:24:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,303
            CDSs (total)                      :: 3,206
            Genes (coding)                    :: 3,061
            CDSs (with protein)               :: 3,061
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 55 of 145
            Pseudo Genes (incomplete)         :: 91 of 145
            Pseudo Genes (internal stop)      :: 26 of 145
            Pseudo Genes (multiple problems)  :: 22 of 145
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR135311.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /isolate="E7240"
                     /db_xref="taxon:1352"
                     /plasmid="5"
     gene            complement(53..136)
                     /locus_tag="EQB75_RS16935"
     CDS             complement(53..136)
                     /locus_tag="EQB75_RS16935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="WP_031929417.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuator leader peptide
                     ErmL"
     gene            complement(185..>268)
                     /locus_tag="EQB75_RS17895"
                     /pseudo=""
     CDS             complement(185..>268)
                     /locus_tag="EQB75_RS17895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502600.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MLS leader peptide"
                     /name="MLS leader peptide"
     gene            complement(678..1472)
                     /gene="aph(3')-IIIa"
                     /locus_tag="EQB75_RS16945"
     ARG             complement(682..1472)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(1565..>1816)
                     /locus_tag="EQB75_RS16950"
                     /pseudo=""
     CDS             complement(1565..>1816)
                     /locus_tag="EQB75_RS16950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /name="GNAT family N-acetyltransferase"
     gene            2061..3356
                     /locus_tag="EQB75_RS16955"
     CDS             2061..3356
                     /locus_tag="EQB75_RS16955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="WP_002297218.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRAC
                     RSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSY
                     FVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSKKIL
                     PRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEEVEFL
                     VTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKSQAEKL
                     KKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAYPFFHEL
                     VEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
                     /name="ISL3-like element ISEfa11 family transposase"
     gene            3457..4365
                     /locus_tag="EQB75_RS16960"
     CDS             3457..4365
                     /locus_tag="EQB75_RS16960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="WP_002324522.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQL
                     KQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKII
                     RYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHM
                     IVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKLALKGITIS
                     VPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAY
                     SVLLSRAQRRFGGTLRYSLGY"
                     /name="IS982-like element ISEfm1 family transposase"
     gene            complement(<4389..4616)
                     /locus_tag="EQB75_RS16965"
                     /pseudo=""
     CDS             complement(<4389..4616)
                     /locus_tag="EQB75_RS16965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(4613..5521)
                     /locus_tag="EQB75_RS16970"
     CDS             complement(4613..5521)
                     /locus_tag="EQB75_RS16970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="WP_001255866.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDI
                     TYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLL
                     PLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPY
                     VIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLW
                     EKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKY
                     TGKTGCLDSTYAADIEERREQ"
                     /name="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
     gene            complement(5554..6288)
                     /locus_tag="EQB75_RS16975"
     CDS             complement(5554..6288)
                     /locus_tag="EQB75_RS16975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            complement(6269..7138)
                     /locus_tag="EQB75_RS16980"
     CDS             complement(6269..7138)
                     /locus_tag="EQB75_RS16980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_002303392.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARSTHTENSDIDIGIYY
                     NSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIKRV
                     EQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIYPTA
                     LKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYCINEK
                     KAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            complement(7153..7377)
                     /locus_tag="EQB75_RS16985"
     CDS             complement(7153..7377)
                     /locus_tag="EQB75_RS16985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_002303393.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLDE
                     LKAIADVLGVKFVQAFILPDGDEIKISNE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(7520..>8341)
                     /locus_tag="EQB75_RS16990"
                     /pseudo=""
     CDS             complement(7520..>8341)
                     /locus_tag="EQB75_RS16990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
                     /name="recombinase zinc beta ribbon domain-containing
                     protein"
     gene            complement(9029..>9517)
                     /locus_tag="EQB75_RS16995"
                     /pseudo=""
     CDS             complement(9029..>9517)
                     /locus_tag="EQB75_RS16995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294514.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(B)"
                     /name="lincosamide nucleotidyltransferase Lnu(B)"
     gene            complement(9572..10252)
                     /locus_tag="EQB75_RS17000"
     CDS             complement(9572..10252)
                     /locus_tag="EQB75_RS17000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            10559..11077
                     /locus_tag="EQB75_RS17005"
     CDS             10559..11077
                     /locus_tag="EQB75_RS17005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="WP_000357244.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSEI
                     FENISDPLPEEDSRFVLDILNMYRDITFSKNKLKDINSIDNYYIQFKGFDFNSSTEFKL
                     ALYAQFFIEKLNRFQEIVEDSDFNTFNSHKPMRGTYIKFLENYNDLKSTNNYQFGNLSY
                     EMISKVLSL"
                     /name="YfbU family protein"
     gene            11084..11596
                     /locus_tag="EQB75_RS17010"
     CDS             11084..11596
                     /locus_tag="EQB75_RS17010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000774078.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKKD
                     IETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLESI
                     FSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSIISQ
                     NMDKLRY"
                     /name="hypothetical protein"
     gene            11867..12490
                     /locus_tag="EQB75_RS17015"
     CDS             11867..12490
                     /locus_tag="EQB75_RS17015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002288897.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVSG
                     KNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLPSF
                     NGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYHANA
                     TGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
                     /name="recombinase family protein"
     gene            12586..13266
                     /locus_tag="EQB75_RS17020"
     CDS             12586..13266
                     /locus_tag="EQB75_RS17020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            13464..14069
                     /locus_tag="EQB75_RS17025"
     CDS             13464..14069
                     /locus_tag="EQB75_RS17025"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            14085..14657
                     /locus_tag="EQB75_RS17030"
     CDS             14085..14657
                     /locus_tag="EQB75_RS17030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002303206.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENCVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(15130..15702)
                     /locus_tag="EQB75_RS17040"
     CDS             complement(15130..15702)
                     /locus_tag="EQB75_RS17040"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_073120187.1"
                     /translation="MCQKNCCHSIISKENLLNQDFSTETICEKWAADITYIPTKKNGWC
                     YLSSIMDLHTKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREV
                     EQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGF
                     YNRNRIHSSIHYLTPQEFEELAKEKMA"
                     /name="IS3 family transposase"
     gene            complement(15803..16965)
                     /locus_tag="EQB75_RS17045"
     CDS             complement(join(15803..16689,16689..16965))
                     /locus_tag="EQB75_RS17045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_086953888.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKWV
                     KQFKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANKHL
                     YPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSKRGI
                     QISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLT
                     YVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFHTDRGK
                     EFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLEL
                     FDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
                     /name="IS3 family transposase"
     gene            complement(17371..17625)
                     /locus_tag="EQB75_RS17055"
     CDS             complement(17371..17625)
                     /locus_tag="EQB75_RS17055"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000199136.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYLP
                     DQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
                     /name="transposase"
     gene            complement(17818..18093)
                     /gene="prgO"
                     /locus_tag="EQB75_RS17060"
     CDS             complement(17818..18093)
                     /gene="prgO"
                     /locus_tag="EQB75_RS17060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            complement(18065..19018)
                     /locus_tag="EQB75_RS17065"
     CDS             complement(18065..19018)
                     /locus_tag="EQB75_RS17065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            19630..21123
                     /locus_tag="EQB75_RS17070"
     CDS             19630..21123
                     /locus_tag="EQB75_RS17070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            21258..21554
                     /locus_tag="EQB75_RS17075"
     CDS             21258..21554
                     /locus_tag="EQB75_RS17075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(21578..22537)
                     /locus_tag="EQB75_RS17080"
     CDS             complement(21578..22537)
                     /locus_tag="EQB75_RS17080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_002287225.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLFF
                     KQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIRCS
                     ARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFKSITF
                     DCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDESF
                     IQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
                     /name="IS30 family transposase"
     gene            22720..23571
                     /locus_tag="EQB75_RS17085"
     CDS             22720..23571
                     /locus_tag="EQB75_RS17085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002287227.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            23592..23804
                     /locus_tag="EQB75_RS17090"
     CDS             23592..23804
                     /locus_tag="EQB75_RS17090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002324171.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIEY
                     RTEYLELTNQTDFLLIRKQQEQEKN"
                     /name="hypothetical protein"
     gene            24237..24917
                     /locus_tag="EQB75_RS17095"
     CDS             24237..24917
                     /locus_tag="EQB75_RS17095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002328852.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDYRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <24971..25114
                     /locus_tag="EQB75_RS17100"
                     /pseudo=""
     CDS             <24971..25114
                     /locus_tag="EQB75_RS17100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /name="chromosome partitioning protein ParA"
     gene            25206..25421
                     /locus_tag="EQB75_RS17105"
     CDS             25206..25421
                     /locus_tag="EQB75_RS17105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="WP_001835296.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETA
                     KNGGNVKEVMDQALEEYIRKYLPDKL"
                     /name="peptide-binding protein"
     gene            25438..25710
                     /locus_tag="EQB75_RS17110"
     CDS             25438..25710
                     /locus_tag="EQB75_RS17110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="WP_000301765.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEVN
                     LLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
                     /name="antitoxin"
     gene            25712..26575
                     /locus_tag="EQB75_RS17115"
     CDS             25712..26575
                     /locus_tag="EQB75_RS17115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016301 - kinase activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="WP_001284311.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGSG
                     KTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAIIS
                     RLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYETMY
                     ADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISP
                     KETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTPPIPKT
                     PKLPGI"
                     /name="zeta toxin family protein"
     gene            complement(26838..27575)
                     /gene="erm(B)"
                     /locus_tag="EQB75_RS17120"
     ARG             complement(26842..27575)
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(4617..5521)
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(9030..9487)
                     /name="lnuB"
                     /gene="lnuB"
                     /gene_name="lincosamide nucleotidyltransferase (LNU)"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic"
                     /identity="100.0"
                     /coverage="56.93"
     ARG             complement(26839..27575)
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     ARG             complement(4369..4616)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="98.68"
                     /coverage="45.56"
     ARG             complement(4614..5521)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="109.42"
     Typing          19631..21123
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tctgtttaaa aagtcataag attagtcact ggtaggaatt aatctaacgt atttatttat
       61 ctgcgtaatc actgttttta gtctgtttca aaacagtaga tgttttatct acataacgca
      121 tttggaatac caacatgacg aatccctcct tcttaattac aaatttttag catctaattt
      181 aacttcaatt cctattatac aaaattttaa gataatgcac tatcaacaca ctcttaagtt
      241 tgcttctaag tcttatttcc ataactttag ggttaaccat acgcaagacc aatcactctc
      301 ggacaatact catgatttta atgataaaat ccatgttaaa cccatagata agaaatacac
      361 ctgcaataac cgttacctgt ttgtgccaat ttaaaaatgc accacttttt tataattaaa
      421 acggttgaaa actgtaccac taataactca caatagagag atgtcaccgt caagttaaat
      481 gtacaaaata acagcgaaat ttttaaatct atttcttatc gatacaaatt cctcgtaggc
      541 gctcgggacc cctatctagc gaacttttag aaaagatata aaacatcaga gtatggacag
      601 ttgcggatgt acttcagaaa agattagatg tctaaaaagc ttgtagttaa agctttttag
      661 acatctaaat ctaggtacta aaacaattca tccagtaaaa tataatattt tattttctcc
      721 caatcaggct tgatccccag taagtcaaaa aatagctcga catactgttc ttccccgata
      781 tcctccctga tcgaccggac gcagaaggca atgtcatacc acttgtccgc cctgccgctt
      841 ctcccaagat caataaagcc acttactttg ccatctttca caaagatgtt gctgtctccc
      901 aggtcgccgt gggaaaagac aagttcctct tcgggctttt ccgtctttaa aaaatcatac
      961 agctcgcgcg gatctttaaa tggagtgtct tcttcccagt tttcgcaatc cacatcggcc
     1021 agatcgttat tcagtaagta atccaattcg gctaatcggc tgtctaagct attcgtatag
     1081 ggacaatccg atatgtcgat ggagtgaaag agcctgatgc actccgcata cagctcgata
     1141 atcttttcag ggctttgttc atcttcatac tcttccgagc aaaggacgcc atcggcctca
     1201 ctcatgagca gattgctcca gccatcatgc cgttcaaagt gcaggacctt tggaacaggc
     1261 agctttcctt ccagccatag catcatgtcc ttttcccgtt ccacatcata ggtggtccct
     1321 ttataccggc tgtccgtcat ttttaaatat aggttttcat tttctcccac cagcttatat
     1381 accttagcag gagacattcc ttccgtatct tttacgcagc ggtatttttc gatcagtttt
     1441 ttcaattccg gtgatattct cattttagcc atttattatt tccttcctct tttctacagt
     1501 atttaaagat accccaagaa gctaattata acaagacgaa ctccaattca ctgttccttg
     1561 cattctaaaa ccttaaatac cagaaaacag ctttttcaaa gttgttttca aagttggcgt
     1621 ataacatagt atcgacggag ccgattttga aaccacaatt atgatagaat ttacaagcta
     1681 taaggttatt gtcctgggtt tcaagcatta gtccatgcaa gtttttatgc tttgcccatt
     1741 ctatagatat attgataagc gcgctgccta tgccttgccc cctgaaatcc ttacatacgg
     1801 cgatatcttc tatataaaag ataacccgtg gtgctagtta attttttcct agaggaaaat
     1861 gtctaaacat gttggtaaat caacaaaaaa acgcatatag tagtctcaaa actcccaaga
     1921 aatgggctct ataatttatg ggactgatga atcagaattg attcttcagc cccattttca
     1981 ttttaggtat taaaaaacat atcgttctct agtatgatta aatcaccaca aaataaacaa
     2041 ctgagaggac gatacgctat atgaatgatt ctatcaaaaa aatgctgaga ataacagaga
     2101 aagatttgat gattacagag gtctcttacg agacccttca gaagaaaaag acgttggtcg
     2161 tcgatgctgt tctctcgcct actcctcgtg cttgtagaag ttgtggttct actgtggtag
     2221 atggaaacgg gaaagcaatt atagtgaaaa atggaaaaaa ggaaacgatt gtccgttttg
     2281 aacaatacaa tcatatgcct ttggttatgc gcctaaaaaa gcaacgctat acctgtaaaa
     2341 actgtcgcac ccattggacg gctcaaagtt attttgtcca acccagacat tcaatcgcaa
     2401 atcatgttag atataaaatt gcttctttac tgactgaaaa agtatcttta tcttttattg
     2461 cgaaaagctg tcaggtatct ttgaccaccg ttattcgtac attgaaagag tttaaaagct
     2521 atttaccaaa gcaatctaag aagatcctcc ccagagtatt gatggttgac gaatttcgtt
     2581 cgcatgcttc catagaagat aagatgagct ttatttgcgc ggatggcgaa acaggaaaat
     2641 taatagatgt tttgcctacg cgtaaattac ctcgattaac aagctatttc ttaggttgta
     2701 ccaatccaga agaagtagaa ttcttggtga cagacatgaa cgccgcctac ttccagctca
     2761 ccaaacgtgt tctgccaaat gcgaaagtcg tgattgatcg gtttcatatt gtcaaacaca
     2821 tgaatcaagc gttcaatgag ttgcgtatcc gtgaaatgaa tgaacttcgt aaagccggac
     2881 agaaaagcca ggcagaaaaa ctgaaaaaga actggcgctt tttgctaaaa aatcgtgcaa
     2941 acatcaacca ttatgaatac aaaacatgga aaagtttccg agcaccaaaa tacccatttc
     3001 ttactgaagc aatgatgatt gatcgattgc ttgagttttc tccgccccta aaggaggcgt
     3061 atcccttttt tcatgaatta gttgaagcct ttcgagacaa agaccctgac ttatttttct
     3121 ccttattggc agaacttccc gaaacgttag atgacagctt tcgggaaaag cttcaaaacc
     3181 ttctgaccta tgaagaaggc atcaccaacg caatgatcta tccttattcc aatggaaaaa
     3241 tagaagcgaa gaatacccac ataaagacaa tgaaacgagt atcctacgga tttaaatcat
     3301 ttgagaacat gagaattaga atctttttga tcaatcaatt aatcaatgta agataacaaa
     3361 aaatctgagc cagaatgtgg ttcattctga ctcagatttg attttgcaca actcatcagt
     3421 ccttattgac aaagagccaa gaaatgagga ctacatatgc gttcatcaaa atatactgaa
     3481 cattatacag atacttttat aacattcaag gaaattatga gaactgtttc taacatatac
     3541 cacaattgtg taccagataa gattaaaaac cgaagaaata ctgatcaact gaagcaacgc
     3601 gatacagtga ttattgcttg tgttatatgg ggtataatta atggctatac tagccaaaga
     3661 gccacgtata gagcggtttg ttccgtctta tttcctaatg gtgactttcc tagtaggagt
     3721 cgattcactc gcttaagttc aaacttagct tacactatca agattattcg atactttttc
     3781 atcaagaagc tcaccaaagg tgaactagtc ggaattatag atagttttcc tagtccatta
     3841 tgtaaaccag ttagaaatag acaagcaaaa ctattgaatc aaatagccaa agttggctat
     3901 aactcaacaa aaaaatctta tttttatggt cttaaaattc atatgatcgt tactaagact
     3961 ggctttccga ttacttactc aatcacgaat ccaggtgtcc atgacgtgaa agtgttagag
     4021 actttatcgg aagaagcgaa tcttcccaat atcctagggg acaaaggata tattagccat
     4081 aaaatccatg aaaagcttgc ccttaagggc attactatat ccgttcctcc acgtaaaaac
     4141 atggataaat cagaaaaact agaccacagc ttacttggaa aacaaagaaa aacagttgag
     4201 actgtttttt cttccttaga aaaattaggt tgtcaaaatt tcaactcacg ttctgttaaa
     4261 gggctagaga gtagatttga aagcatatta ctggcttaca gtgttctatt aagtcgagca
     4321 caacgacgtt ttggaggaac tttgagatat tctttaggat attaaaatta actagcacca
     4381 cgggttaaaa gatatattat cttatcagta ttgtcaatat attcaaggca atctgcctcc
     4441 tcatcctctt catcctcttc gtcttggtag ctttttaaat atggcgcttc atagagtaat
     4501 tctgtaaagg tccaattctc gttttcatac ctcggtataa tcttacctat cacctcaaat
     4561 ggttcgctgg gtttatcgat atctttcagg tgccctgctt tcatttctgt aatcactgtt
     4621 cccgcctctc ttctatatca gcggcatatg tgctatccag gcagccggtt ttaccagtgt
     4681 attttttata catgtccctg gtatattttg ttatattcct atcatactcc ggataggcat
     4741 aatgaagcct ttccgccacc tcaccggata ccgccctgaa caattgatgg catagaaata
     4801 atgcttccca tatgttttca taggaatcca tccggtaggt ggacaaaagt ttctcccaca
     4861 aatcctcgga tatatacctt tcaataaact tatagttctt gcctacactt aatttaaagc
     4921 ctgtttcgat gccgaccttc catgatatca ttctcagcag ctcatggcga acaatctgat
     4981 taaaatgatc aatagcaaat aaaatttcct tacggcacaa tcctttaata acataaggtg
     5041 ttacattcca aaattcattg cagcaatcat catactccct tgcgcttggc tttcttacat
     5101 gataatctat atcagtcgga actatgtccc ttttaattct acaatcttta tcaattagaa
     5161 cctttattaa tttatcgccc tttaggtaat tatctaactc ttccaagggc aataaggtaa
     5221 gatcaatttt attgtaatca tcaaatagca taagatagga aaatcccttt tcttcaggtg
     5281 ggaataattc catatcctcc ggcttttgca tcattattat attcccaaat tgattaagcc
     5341 agtcatcatt agatataaac ggttctatat cacttacaaa atatgtaata tcataatcct
     5401 gaaattcatc tttaggtata ttaatatttg cgcgtgaccc ctcaagggtc acaattcgaa
     5461 tacgttcatc ctgttctgct aaagaaagta ctaaatccat catttctttt tctgatctca
     5521 tttacatact cctcgtttat tttttctata ttattacatc ttcttttttg ccgatacaat
     5581 cagcatcatt gggcgtcgca tttcatccgc catccccgga atatccatca tgttctctgg
     5641 cggctgtggc tccacaatct gatttattat aaaactattt gaaagcagtg tatttagata
     5701 tgtggtcagt gttctatgat attttgtaac cttttcttcc aaaaacatag ctgtccgttt
     5761 gccctcataa taataattgt ccaccgggaa atgcagtatt tctccttttt cgttataata
     5821 ccagtcttgt gttccatgag cagtaaaaac aggatgttca actgtaaaaa ctaaattgcc
     5881 accagccttc agcatcctat atatcttttt tattaaattc tcatagtctg ctacataatg
     5941 aaacgcaagc gaacttagta ttacatcaaa gctctcctct gggaaatcca catcttctat
     6001 ggcacagcat tcatattcaa tctgtggaaa atgggttttt ccttttgcta cttcgagcat
     6061 tttatgagaa atatcaacac ctactacaga ggaagcaccg ttttccatcg catatataca
     6121 gtgccatcca tagccgcatc ctaaatcaag cacacgctta cccttaaaat caggtagcat
     6181 ctttttcaaa gtctcccatt ctcccgcacc agccagtcct ttctgcgagc gactcatttg
     6241 actgtatttt tgaaaaaata tattatcatc atatttgttt tctttcatct gaactctcct
     6301 cgtttaaaaa gttatttatc tccgatacaa tttcattcac ttctttataa agtttctcgg
     6361 tcatgtcgta gcattcaaaa agagaaagac cgagtacttc aaaaatatga ttaactcttt
     6421 cggcatattt ttcaggttta tattcaaaag tttcaagcag ttttatagct ttcttttcgt
     6481 taatgcaata agcattatta catgcaaata gtacttgatt taagcatgaa ataatacgaa
     6541 aaacatggcc tgcaatataa tatttatcct ctgcccccgc atttgctttt acaaacatta
     6601 aagagaattc agcttcaaat ataaaaaagt tcatcaagct tttctttaga gcagtagggt
     6661 aaatttctgc ctgctttttt aattcgcata agctttcgtt cttagcatat agtattttac
     6721 taatcgctaa ttctccacga tacatagcac ttatataacc atggggatgc ccggtctgat
     6781 aattggcagt aacaattcct tgctccgtat ctttgattat ttgttccacc cgttttatat
     6841 cacgtaatat caagtcaaca tgacacccgt ttataactaa ccatccaccg ccattaaccc
     6901 aatcacccca cgctccggga ggtacaacaa ggttgtttct attctcatca tccaactctg
     6961 tagcaatttg attaatcgct gtcaggtcaa atgagtctga attgtaatag attccgatat
     7021 ctatatcaga attttctgta tgggtgcttc ttgcacgtga gccccctaat acaatgcctt
     7081 ctataaaagg caaagatgat aatttctctg ttactatttg aataacatta cctaccatat
     7141 aaacatcctc ctttattcgt tagatatttt tatttcatct ccatctggta aaataaatgc
     7201 ctgcacaaac ttgacaccta gcacatcagc aatggccttc aactcatcca aggttactgt
     7261 ttctcgttgt aattttttat taaaattctg tggagtctgg ccaatacgtc tagcaagttc
     7321 ggaaacactt atattcattt gctcacacag ttctttaatc atttctgccg tagtcataca
     7381 gcacctccaa gtttatgcta agaataacat aaaccatttg gttgataaat gcaatagtca
     7441 ttaaaatatt attataatca gcaattaaaa gaaaacccac aactctactt cagagtcatg
     7501 ggctatttac ttctggtttt catatttcca tttcgatacc tggtttgaag gctatgacga
     7561 agtggtcttc atagacctta acgttctgga ttatcttcct tacaagctta tcatcatatt
     7621 ctaaggtgcg gaatttgttc ttgcggataa attcaatcaa ctcattgatg cgctcgttct
     7681 cgccactgag ggaggcatct tctactaaaa gagtctgacg cttatctcgc atctcatcga
     7741 tctcatctac caggtattca taatcttgac ctttattggc cagcttgatt agttcttttt
     7801 gtttttcatc tagtagggta ttaatctctg aaatttggta ttctgtggtt tctccaatca
     7861 cagcatgaat attttcttcc agtgtcttta tcatattgtt gccaccagca agtagcttat
     7921 taattgcggt cattaccgca ccatagagtt catcttcttt tacggttcgg ttcttacata
     7981 cctcgggacc ctgctcgatt ctagtcacgc atcgccagac aaattctttt ctgccatgaa
     8041 tattccaata ggttctccta taaatatcgc cacaatatcc acagaaggtg atggcactta
     8101 aagcgtactt gctactataa attcttttgt tcttgccttc tcctgtgtag atattacttc
     8161 tccgataaat ttcttcttga gcctgcaaaa ataactcttt agaaataatc gcttcatggc
     8221 tattttcaac ataatactgg ggaaaatgag agattaacta cagtctcact tactggctag
     8281 tgacagtaag cagacacact caacgtttag tactcaggcg atttagggat caagtcaaca
     8341 aacactaaaa actattgatt gcataggatt tttaagcatc tcctaacaac ccaacatcta
     8401 atctatcact tcatttaagt agggtatttt agtttcgctg ttaaaatcaa gcctattttt
     8461 atctgtggat gtaaatccta ctaatatccg attctccact cccttaagcc atgcaaagaa
     8521 attctaaacc atatttgcac caaaaagaga ttaaccacta gcggatcgaa gaaaaacacc
     8581 ttgtctcagc tacgtcaaaa gatgaaatgt gagtgacgct agattcgtgc ttcagcaatt
     8641 ctaggatcga agcggtctcg cagcccctca cacaaggcgg ttttccatag gatagcgcga
     8701 gattcaatca ccactatttg ccaaagagcc caaaaaaccg ctagccaaaa atcggctacc
     8761 ggttctaaaa atgatgttta tccttttcga gtctaacaac tcgtcaggac gaacaataat
     8821 tattttcttg ttaacagaca tactgcttcc acatggattg agaggacaga atgaatgtca
     8881 tttgtgtatg tccgttctcg gaaacatatc cacgacactt tttgcactat cggtagacgg
     8941 gaacatatcc ataggcttcg ctgttttttg aaaaactgag gtatgctgtt aattttcagt
     9001 acccaatact gtgaataacg ttactctcct attcactaat gtaattcaac aatctttcta
     9061 aaatgtcatg tgtaactttt aagttgtatt gttcaataag gtgactttgc aaatccataa
     9121 ctaatagcaa agaattttta taggcttcaa ataattctac cttatctaat cgagcagtgg
     9181 tctttgcaaa ttttttataa ttttcaaggc taatttcttt ttcaaggttt ttactcatgt
     9241 ttagccaatt atcagcattt ttttctgcca tacgtataag ttgtagtgta tttttttgaa
     9301 gttgtgataa gagttctaat gaacgagcat attctcctct ttttagaacg ttgattccca
     9361 tcaaccatag attagagaaa ttacacaaca aaaaattagc attttcttca gtaagtctat
     9421 ttggtcttgc accacttatc tctgataaat aattttctaa ttgccctgtt tcatcgtaaa
     9481 taagcatagc cttcgtatca ggaatataac ctgaatcggt tctgttgcaa agttttaaat
     9541 aaagaataaa atcccttacg gtatctatga tttaagctgg gattcccaat aataccttga
     9601 tttcagtaca gaccgaaaac ccgaagagag tgccttcttt tcgggttttc ttatataatc
     9661 ctcgaatggc ttccatgcct ttaatcgtgg tagaggcagt gcgtaaactt cgatagaatt
     9721 tattgcgtct ctttactgga cgatggtctt gttcaatcaa attattcagg tatttaatgg
     9781 tacgatgttc tgtcccttga taaaagccgt attcttttag tttcttaaag gcacttgtaa
     9841 tagagggggc tttatctgtg actacaacct tcggttcatc aaactgcttc actaaccgct
     9901 taagaaaagc ataggctgct tgtgtgtccc gttttttacg taaccaaata tccaaggtta
     9961 aaccatctgc atcgatggct cgatacaaat aatgccattt tcctttaatt ttgatgtacg
    10021 tttcatccat tttccatgaa taaaaggatt ttttattttt ctttttccaa atttgataga
    10081 gtagtttgcc atattcttgc acccaacgat aaatcgtcgt atgagaaacg ttaatgccac
    10141 gatcatataa gatttcttga acttcacgat agctaaggtt ataacgaaga tagtagccca
    10201 cggctacaat aatcacatcc tgctgaaatt gctttccttt aaaatgattc atcgtcattc
    10261 ctcctgctat ctttttctat tattctacct tatttgatag tagatttaaa actttgcaac
    10321 agaaccttac tgccgtagcg aaagctagcg attcgatttt agcttggtta aagttcaaaa
    10381 aagaacaaaa aaaatagagc cgtctcaact tttggcgagg tagacgagct ctaaagcttt
    10441 atttacatgc catccgcttt gaacggacta cactgggcat gtgacagcat gccctttcat
    10501 ttatattata tctcattctt ttatataatg aaagtaaata aatcatggag gataaaatat
    10561 ggataaattt aatagattaa cattaataaa tcagtttgaa attttaaaag ctttaaatcc
    10621 taacgaagaa aaatactatg ctgaaaaaat agaaatacta acagaaggtt acgaatatca
    10681 ctatagtgaa atatttgaaa atatttctga tccattgcca gaagaagatt cgcggtttgt
    10741 tctagacata ttaaatatgt atagagatat tacttttagt aaaaataaat taaaagatat
    10801 aaattcaatt gataattatt atatacaatt taaaggtttt gactttaata gctctaccga
    10861 atttaagtta gcactttatg cacaattttt tattgaaaaa ttaaataggt ttcaagaaat
    10921 agttgaagat agtgatttta acacttttaa tagccataaa ccgatgagag gtacttatat
    10981 aaaatttctc gaaaattata atgatttaaa atctaccaat aattatcaat ttggaaactt
    11041 gtcttatgag atgataagta aagttctaag tttgtgatga taaatgaaat taaatagtat
    11101 aaatgattta tttgctatta taggtgttat tgctaacata cttttttcgt gtttgaattt
    11161 tagatttact caaaagaaca aaaagaacaa actcagtata gaacaaatga aaaaagacat
    11221 tgaaactgat ttaaaaaatg accataaaga aagaagaaaa attgaagaat atacttcttt
    11281 aatggaaaag tgtaaagcaa ctgatgcaat ttttagcttt ttaagaaaaa gtgatgagat
    11341 aatcacacgt gaaaatatag atttagaaaa tgagattagt aaacttgaat ctatcttttc
    11401 cgatataaat tctcttaagt atttaatcgt cgaagaaaat tcggatagct ttttagaatt
    11461 tgaaaaatat ctaacagatc ttatagataa tagaaataat gaattaatga gacaaaacat
    11521 tgcaagattc cttactaaat tagtttctga atggaaaagt attatttctc aaaatatgga
    11581 taaattaaga tattaaggat gttagtttta aaataaacta atgtccttat ttttgtgttc
    11641 acatttctgt tacctaagaa atacttaaag gaggtgatgt agccagcaac gactacaact
    11701 tgaacccgct atctacagtt tatttgttgt ttcttttggg tatactctaa tggtacaaat
    11761 ccatatttgc ttaaagcgtt gatttttcag cggtttttct ttattgcaaa gtgtacccta
    11821 agacctgtat actaatagta aatagattgg ataggaatga tggcaaatgt atttagctta
    11881 tttaagagtt tcttccgacg atcaaagttt agctcggcaa cataagctaa ttgaaaattg
    11941 gtcagtcaaa aataatattg ctgaagacga tttaaaaatt ttcgaggaaa aagtctctgg
    12001 aaaaaatatt gaaaacagac cagagctgca agagcttatt tctttcatac gtgaacgaga
    12061 tacgattatt attcctagtc ttgatcgatt agcaagaaat agtaaagata caaaagactt
    12121 acttcaattg tttcgtagta aaggtgcttc tattgaaata ttagacctac cgtcgtttaa
    12181 tggggtaact gaccctgcat taagagactt gctaacaaat ttagtcatag aagtgtttag
    12241 ctatgttgct gaaaacgaac ggaaaaaaat caaagagcgt caaaaacaag gcattgaaat
    12301 tgcaaagaaa aatggtcgtt atactggtaa aaagattcaa taccatgcca atgcaacagg
    12361 aaaaaacaaa ttgatttacg atgaaattgt tgatggtctg aagaaaaaag aaactatttc
    12421 taaaatagca aagaacgcag gagttacaag aaaaaccgtt tatcgagtaa aaagagattt
    12481 aggaatgtaa tatgttccag ttagaaagaa gggttctgtt gcaaagtttt aaatctacta
    12541 tcaaataagg tagaataata gaaaaagata gcaggaggaa tgacgatgaa tcattttaaa
    12601 ggaaagcaat ttcagcagga tgtgattatt gtagccgtgg gctactatct tcgttataac
    12661 cttagctatc gtgaagttca agaaatctta tatgatcgtg gcattaacgt ttctcatacg
    12721 acgatttatc gttgggtgca agaatatggc aaactactct atcaaatttg gaaaaagaaa
    12781 aataaaaaat ccttttattc atggaaaatg gatgaaacgt acatcaaaat taaaggaaaa
    12841 tggcattatt tgtatcgagc catcgatgca gatggtttaa ccttggatat ttggttacgt
    12901 aaaaaacggg acacacaagc agcctatgct tttcttaagc ggttagtgaa gcagtttgat
    12961 gaaccgaagg ttgtagtcac agataaagcc ccctctatta caagtgcctt taagaaacta
    13021 aaagaatacg gcttttatca agggacagaa catcgtacca ttaaatacct gaataatttg
    13081 attgaacaag accatcgtcc agtaaagaga cgcaataaat tctatcgaag tttacgcact
    13141 gcctctacca cgattaaagg catggaagcc attcgaggat tatataagaa aacccgaaaa
    13201 gaaggcactc tcttcgggtt ttcggtctgt actgaaatca aggtattatt gggaatccca
    13261 gcttaaatca tagataccgt aagggatttt attctttatt taaaactttg caacagaacc
    13321 aactagactg tgcaaaatag agacacttga aaaatctatc gggggtcaga aacttaatag
    13381 tttttgacac ataaacaaaa tcgcgatata atggggttga gagtgtttca taaacttatg
    13441 tcataaagtt aaggagattt cgcatgattt tagagaataa attgggatta accaatcaag
    13501 ttgagttggc taaggttgaa gaaaaactca gtaaacaaaa agcgaaagaa ttgtacgatt
    13561 gtggaaaaat aaatgaaatc gaagttggta catttaaagg tttatctgaa attcatgaat
    13621 ttctattttc ggatatttac gattttgccg gaaaaatccg atcggtcaat attgcaaaag
    13681 gaaattttcg atttgcacca gttatgtatt tagaacattc gttacagcat attgatcaga
    13741 tgccacaaac ttcttttgaa gagattatca agaaatatgt ggagatgaat atcgctcacc
    13801 catttcgaga aggaaatggc cgaagtacta gaatttggct ggatctcatt ttaaaggaag
    13861 aattgcaaaa agttgtagat tggaacttaa tcgataaagc agactatctt tctgcaatgg
    13921 agcgaagtcc cataaacgat ttggaaatac gctatctaat ttccaatgct ctgactgata
    13981 aaattgacga tcgcgagtta tatatgaaag gaatcgatgt cagctatttc tatgaagggt
    14041 attctgagta tacgatagat gatttgtaaa agtaggtgga ccaaatgacg aaatatggat
    14101 atgcacgtgt ctcaaccgct tctcaaagta caaaagaaca aattcaacag ttgcttgaga
    14161 actgcgtaga gaagaagaat attttttcag aaaaatttac gggtacaaaa cgggatcggc
    14221 caaaattcaa tcagctgttg gctggtctga agcctggaga tgaaatagtt gttacgaagc
    14281 ttgatcgatt tgctcgtaac acgagagaag cattagagat cattgaacct ttactcgatg
    14341 ataacgtaac gatcaaggtt ttgaatctag gaacgattga aaatacgtcc atggggcgaa
    14401 tggtgacacg gacgttgttg agtgtagcag aaatggaacg tgatatgatt gtggaacgta
    14461 cccaagaagg aaaaatgttt gcaagaaaga ataatcctaa tttcagagaa ggacgtccga
    14521 aagcaacaat cacaccgaag aagaggcacg catatgaact gcttacttca ggtaaatcgt
    14581 ataaggaagt tgaagctata accggtttca gtcgcagtac gctttttaga ataaagaaga
    14641 aaattgaaga aagttaaaaa agaagtctca gcgaaccaga caggtaaata cttaatgcgt
    14701 tctagatatg agtctattag catgttgtga aatataatat ttttttattt acttgatttc
    14761 tgctcaaaaa atgtgtatgg taactgtaaa aggtaaagta attaaaggta tgctagccac
    14821 gcttactata ttaggatacc atcatatatt tataatgaac gatttgttcg tctaccaaac
    14881 aacacatatc gttcagcgta agtcacgttt aggaacgtgg cttttttagt gttattatcg
    14941 ataaataatc tattgactct attgatttta tctccatatc cctacggtgt tgattgtctt
    15001 tagatctttc atttaagaac caaataacta tcataaaaat cagcactgct gctaatataa
    15061 taaacagcat tcctattgtg atattactgg atttgagtca atatcttgga cacattttag
    15121 tagagacggt taagccattt tttcttttgc taattcttca aattcctgtg gggttagata
    15181 gtgaatcgag ctatggattc gatttcggtt ataaaatcct tcaatgtagc taaatagcgc
    15241 tcgatttgct tcttcaaaat ctgagtagct agtcgtgtag acttcttctt ttttcaatga
    15301 ggcatggaaa gattcgattc cagcattatc ataaggtgtt ccttttctac tataagaatg
    15361 ccttattttg ttggttttaa gccattgttc cacttctctt gctgtgtatt ggctgcccaa
    15421 gtcagtgtgt agaatcattc cttctggaat gtgataatgt atttttgctt tattcaatgt
    15481 ttgaatgaca caatccacag tcattcgttt tgaaaatgta taactaataa ttcttttcgt
    15541 gtgtaaatcc atgattgaag ataagtaaca ccaaccattt ttcttagtag gaatgtacgt
    15601 aatgtcagct gcccatttct cacagatcgt ttcagtagaa aagtcctgat ttaagagatt
    15661 ctcttttgaa atgatggaat ggcaacagtt tttttgacaa attttataag gtgcagaact
    15721 tctttccgta tgctattccg attgtccttg acaatgagcc tcctcggatg tgacgatctt
    15781 cggcaggagc taacagttaa agttagactg cctcgctagc gttagcacat ccgagctcat
    15841 tatcaaggat tcgctgcgcc aatctctggt tacggtaacc aaccggtgtc tcgtagccaa
    15901 gtgtaccgtg caaccgaagg tggttccacc aattgacata gtcaaataac tccaaatcca
    15961 attgttgtaa ggtttcaaat gtgtattgat agacaaattc tactttcaac gacttataag
    16021 ttgattcagc tacggcatta tcaaaaggac agcctttatg actcaatgat cgattgatgt
    16081 caaaagttgt taataattca tcaatagctt ggttatcaaa ctcttttcca cgatcagtat
    16141 gaaaaatctc aacctctgtc agaggttgtt tgatacggct aaatgctttt tttactagaa
    16201 cggcatcttt atgttctcca caagaatagc cgagaatttc tcgattgaac agatccaaaa
    16261 tgaaacagac ataattccat tttttcccga ctcgtacata agtcaagtct gttacgatcg
    16321 cttctaatgg gttgtctctt aagaatttac gattcaatac gtttgtcgtt ttggcttcat
    16381 tgcaagtaga atgatgtact ttaaaataag caacagtata gctcgatttt aatcctctat
    16441 ttttcatgat tctactaatt tttcgtcggc tgatctgaat gcctcgtttt gataaggctt
    16501 tttttatttt tcttgagccg taggcctttc ggctgcggat aaattcttca gcgactactt
    16561 cttcaagttc tgattcgtct ttctttggtt ttgattgata ataataggac tgacgtgata
    16621 gacctaatat tctgcacatc gctgatatag ggtaaagatg cttattcgca tcgattactt
    16681 gtctcttcgt ccgaatatca gcgctgcttg ctttaaaata tcattttcca tttctaattg
    16741 ctggtttctt ttacgtagtt ctaacaattc tttttgttca ggcgtaagat tatctttttc
    16801 tttgaatgaa ccactcgttt taaattgctt tacccatttg tcaaatgctg aagccgttag
    16861 ttcatattct cgaatgattt ctacacgtgg ctttccagct aagtaaagat tgacgatttg
    16921 ttgcttgaat tcttgtgaaa aagttcttcg tgttctctta gacataaaaa ttcctcctgg
    16981 tatgttttct tctagtctac acaccttaat ttttctgtct agttaattgt agcctatcca
    17041 tgatcggttt attagacctt tgaggtctat attttttaac tacaatcgac cttaaattta
    17101 attgtttcat tagcttttgg acatgtttaa gagatactga aatcccttct tttaataaaa
    17161 cttgatggat ctttgtggca ccatagcgtt gtttattcgt aaaaaaaatt gttgaaatct
    17221 tctttttcaa cttattattt ctgatttctg tagctgtcaa cggtttattc ttataaaaat
    17281 aatagacact tctagggatt tctaataacc gacacaacaa agaaacagtg taatccttac
    17341 accatttttc aataaattga acaagcgaat ttaggttttc cgagagaata tggctgcggc
    17401 tttttttaag atttcaagtt cctcatttaa acgagcattt tcttttctca gttcagctac
    17461 ttcttttcca gtcagtcctg tggactgatc aggtaaatat aaattcttcc atttgtaaat
    17521 cgttgcttca gataagccat attctttcgc taaccctcga acagaacgtc cagtttgatt
    17581 cagttcaaca atcatttgtt taaaattttc ttcatatcgg gtcataaaaa ttcatcctct
    17641 cgtagataag tttaatttat tcttgtctct acgaaaagct gtctaagatt tgatactaac
    17701 accaaatgtt gtataccccc aaacaataca catattttga aggattagga ttaataaagc
    17761 taaaaatata gtaagtatac taaatatatt tactatatct agtatactta ctatatttta
    17821 atcttttgat cgtctattat atataatccg ttcctcgtcg tttaaagtat caacataggc
    17881 gtccattgca agtttgacta tttcatacat aggaatatct tttgcataac taagatcccg
    17941 aatggttttt agtacgggag gatctacttg aactggtttt ctttctttcg cagtgtactt
    18001 tcgttcccct aactcgacat taatatcatc tttaattgaa atatcttcag caccaatttt
    18061 cttcttatct ttgttcgttg gtaataatgc catttagttt aatctccttt ccaagaggta
    18121 ggatatgatt ggccattgag tcagcatatt taggtgtata atcaaatcct tcaatatcac
    18181 catgttgttc atagtattca attctttctt ctaattctgt aaagatgtct gcaaaaatag
    18241 cccaccatct tcgatctaca taatcattta attggatacc attctcacca tacatttcta
    18301 accgatccga gcctttaaca atgcttttaa aaatgtttga ttcaccatac ttatcaattg
    18361 ttttttgata gtttgcgtgt tgagaggaac gtcgcactga gaaaagaaca ggcaaaattc
    18421 caatgatttg aagatgagac tcttcaaaat tcgtgacaat cggaactaaa actttattaa
    18481 taaaatcttc tgttccttcc attgcgtacc gttttaattc ttgcattgca ataatataat
    18541 ctgcagcagt taagaatgca cgaaccacat tatctgttga tggtgggcag tcgataaaga
    18601 tataatcgaa attttttctc aattcttcta aaggtttaat gaaggccaat gatctcttac
    18661 gacgatcagg atatttttcg gacaagtatt cattaagttc ttcagatcca ggagagccag
    18721 ccataatata taaatgtgga cttacttgag taatacctga aacccagtcc ccttttttga
    18781 ttgctgcaga catggatcga tcaaagctag taatttgata cgttgatcca atgttggaag
    18841 tagtatttct ttgttggtca taatcaatta gcaacacgtc tttttcaaaa agttgactag
    18901 aaacaatcgc taataaatca ttgtctgtag tcttaccaat gccgcctttt ctacctgtaa
    18961 gcattacaac ttttcctagt ttatctgatg ttttaaatgc agtccgtaag ttttccatag
    19021 ttccctccaa tttcctatac taaatatatt tagtatactt catatactta atatattcga
    19081 tatatctaat atactccaaa ttgataagaa ttcagacttt ataaggaata tagtggatat
    19141 actaaatata tttgctatat tcagtatatc agatatattc aaaatgtcaa aatatatttg
    19201 tgcgttttgc gttgacaatt tagagtgaaa agaggtaaac ttaattctat agaaaccaca
    19261 gataattcac tatttacaaa gtagcaaaag cagtggtact ctttaaacag aaaaattaca
    19321 taaaaaaaag agacggaaat aattgatttt agcagaatca attatttctg aatcacatgg
    19381 ttaggacatg tgttcacgct cgtctcaaga atatgtaagt agctaccaac tacttatatt
    19441 aaaagttgat cggatacctt ttccgattgc ctttattcta ccaaaaaaag gcgagcaact
    19501 caacagaaga acgtttattt agtgtactta aattaaatat tcttaaacac tgaagagaga
    19561 acacatacta tggctgagat taaagctaaa ctgtgttctc tttttgtttg agaaaggacg
    19621 ttacaatcga tgttgagcga aatttattca gctattctta aaaacggctt acgtacatac
    19681 aaatatcgaa acagcaccat gaaacctgca ggtcatattg attccagtag gagtggtgct
    19741 atctttgcgt accgtagcaa gcaattaatg aatgttgggc gtggtatggt cattacttcg
    19801 gaagaagcta ttttagagaa cgaaaagaaa ctaacgcatt ggacacctaa tacctatcgc
    19861 tttggtactt atgcggatga ttatcgaaca gtggttaaag gtcattctga gaaaaactta
    19921 agtcaaatca acacatttgt agttgatatc gattcaaaag agaaccatca aggcgaaatt
    19981 attttagcct gtttagatca agtgggctac atgccaacgc taattttaga atcagatcat
    20041 ggttatcaag tttattttgt actaaagaca ccaggctatg tcacaaagaa aagcaatttc
    20101 aaggtgatcg atgtagcaaa aaaaatttca aaaacaattc gtctacagtt ggctgaaaaa
    20161 ttgtccggag tggatctagg atgtaaccac ttcggaattg ctcgattccc acaagaaaat
    20221 aatattgttt ttaaagaaat gaactatcag tattcttttg ctgactggat tcaatggtcg
    20281 atgaagcttg aatcagatca aaaaacaaaa gaagatcgag aacgaaaact aattgtcttt
    20341 cctgagaaaa aagaaattcg tcaagtagat gaaccgtggt tcgatatgtt acttcataaa
    20401 gcaaacatcg tcggcggaga aggacgtctt ggtcgaaata atgtgatttt cacgctttct
    20461 ttagcttatt actcttcagg ttatgcattg gatacttgcg aatacaatat gttcacattc
    20521 aacgaacggt tacaggaacc gctatctgaa gcagaattag taaagattgt acgtagtgct
    20581 tattctggta attatcaagc agcaagcaga gaattcatta ttgaattgtg ccagcaatgg
    20641 gtttcaccaa ccttaaaaaa taatgatctg ttcattcaac gacgtggctg gtggaaattt
    20701 aaaaagccac gagatcaaag aaaatatagt cataaaaatg aatggaaaga agatctattg
    20761 gcttatctaa gcgaaaaaag tcttgctagt gagccttatt tgaacctgtc aaaaaaagaa
    20821 ttggcttcac aactaacgat gcccaagcga acacttgata agatcttaaa tgagttacga
    20881 gaggagaata aagtcttcta caaggtaaca cgaggaagaa atggcggaat gatcattgct
    20941 tcagtcaaaa cgttgttcgc gagggttatt caactaagta aagaaaagag actagattat
    21001 tcaacaagga tcacagaggt atttggactc aacgagagct tagtagaaga gacatttaga
    21061 caattatcaa cccccttgaa ccctcttaaa gaagtgaatc tttttgaagt agatacaggt
    21121 tgaaaaataa aaggtgcaaa ttgccttata caatatatct atgatacttc tgtaggtgtt
    21181 gctccctttg cctagctacg tgtaggtggt atacttataa ctgcgtatgc agtcttatgt
    21241 atcatggagg aagttgtatg tcgttaaaaa attatgtcta ttcacatcct gttaatgtgt
    21301 ttatcattgg tcgtttggga ttatctgtgg aagtgttctg tgagctttat ggttttaagc
    21361 aggggacttt gtcttcttgg gttaccaggg aaaaaacagt tgcttctttg ccgattgagt
    21421 ttcttcatgg gttgtcctta gcttctgggg agactatgga tcaggtatat gattgtttgt
    21481 gtgtgttaga gcaggagtat attgagtata aaatagctaa cgagttaaga aaaaggaaga
    21541 agtatatcca gtagtagttt ttatttactc ttaattgtca aattaagtta gacaaatcat
    21601 caatacttac gtaactcaaa aatacttcca aaggtgttcg ataattcagt gattttctag
    21661 gaatattatt tcgtttcgat gcgacagatt gaataaaaga ttcatctact gaattgaaat
    21721 ccatagattt caataaacca tctctacgta acaatccgtt agaattctcg tttaggcctc
    21781 tttgagacgg cgttcctgga tcagcgaaat aaatggcaat atcattggca ttactgatct
    21841 gtttccaatt tgaaaattcc tttccacaat caaaagtgat ggatttgaat agatttttcg
    21901 gtacagattc aaaccaatga tttaatttgt tttcaatatc aatcgcttgt ctaccacacg
    21961 gtttcaatgt gatgataact tttgataatc gctcaactaa ggtaattaca gcacttttat
    22021 gtttcaaacc tacgatagtg tcaccttcaa ggtgaccaaa ctcatttgag aattggctat
    22081 aatctttttc acgttcatga atagagcgac ggaaagcttg ttttccacgt ctttcttgat
    22141 gtccatttgg tttacgcttg cctttcatcg gtaagtcaga aggattaaat agcccctttt
    22201 tgaacatacg ataaatggta cgagcagaac aacgaatagg aaacgctgca cgaccaacaa
    22261 tcacatcggg tgtccatcct tgaacaacct ttctttgaat atattctgat tgttcctcag
    22321 gtaaaacaag cgggcgtcta ccacagtttg atttgttttt cttatactgt tgatagtact
    22381 ctaaggctga ttttccttgc ttgaagaaca ggtatacttt atggatcgtt tgtcttgaac
    22441 gattcaagaa atgcgcagtt ttcgcaacag attgatttat tttgaaataa gactctatca
    22501 ttacaagttc atccgttgta agatgggtat aggtcatttg tactcactcc ttataattct
    22561 ttggacggaa ctattttgag tgtagcacaa atgacttttt tagttgtcta gcttaatttt
    22621 acaatcggcg tacttaaaaa attggttcat tgagcaacct atcgctgcta aagtagcaaa
    22681 ggaaaacgtt aaaggaaaga atttagggaa gaaatcgaaa tgaaatcgga cgactggatt
    22741 gaacacacct ggcttcctct gaaaagaaat agcaaacgaa agaaattttg ggtattgcaa
    22801 ttatggccat taggaaaact ttgtagttac ggggcacgac ttattcttga tttaaccgtt
    22861 tactcgattg gagtatttgg aacggcttat tacttgataa atgatcccaa taggattgca
    22921 gcatcagaca tttttacagt gctaatgacg ttgatttttg tcatgctatt gtctattttt
    22981 actcaattag tcatgcaatt taccaggcaa aaattaacag caggaaaact tttcaaaagc
    23041 ctattcgatt taattgttgt aaatgcaatt ctagcgactt taataaaaca aattgaacaa
    23101 tctggaagaa caacaaaagg agtgaaggat tttttattga cgtttattca ctttgtaaat
    23161 ggacacatgt atttgtttga agtgggtatt attctctttt ttgtcgggta tgtatccacg
    23221 aaacttatta aacgttcaat tgaaaaagaa attgaaattg acctgattcc gacacttctt
    23281 ggttatgagt acaatgttga ttttggaaga tatgacgaat tgatcaatac ggatatcgtt
    23341 cacacgagta tccatgaatc tactgttaag ggcatcagat ctattttaaa aaatggccag
    23401 gaaatgaaag caatagatcg aagaaaagag atctacaatt tttatgaagt cgaagcaagc
    23461 ctacgatatg gcatcggaaa attgtggtta gatggaagta atattcgtca aaacaaacca
    23521 tacatttttt ggaacagtag tgatttagaa cttccaatga aagataaata attatggaga
    23581 atcgtttgaa aatgattcct ctatacagga ttgtgcttat agttggcatg gagttaaaaa
    23641 ccttaaagaa ggagcagtta ttcaaagtga aagaacgtca taatcagtta ctatgtagta
    23701 aaacgggtac gatgaacatt gaataccgaa cagaatattt agaattaacg aatcaaactg
    23761 attttttgtt gattcgaaag caacaagagc aagaaaaaaa ttaatggcta cttatagcca
    23821 attgattgat gaatgggaac aattcaagga atctaaaatt ccagaacgtc tctaaaagcc
    23881 tttatttgta aagagcataa ggaaacgtgg gaacactttt taaaaaaagt gttccaatag
    23941 gctgtgccta ttacgtttct caaaaataaa tgtgggaaca aaatatttaa aaataggata
    24001 gtgaaaggat agtgaaggat agtaaaagga gggtagtagg atagcaaaaa ggataggctc
    24061 cttttcgcta tcctttttaa attggaggaa ttaatatgga agtaagaata agaaatgtgg
    24121 atgagaaaat cgtaagagaa attgatcgaa gatgtgacga acggttctgt tgcaaagttt
    24181 taaatctact atcaaataag gtagaataat agaaaaagat ggcaggagga atgacgatga
    24241 atcattttaa aggaaagcaa tttcagcagg atgtgattat tgtagccgtg ggctactatc
    24301 ttcgttataa ccttagctat cgtgaagttc aagaaatctt atatgatcgt ggcattaacg
    24361 tttctcatac gacgatttat cgttgggtgc aagaatatgg caaactactc tatcaaattt
    24421 ggaaaaagaa aaataaaaaa tccttttatt catggaaaat ggatgaaacg tacatcaaaa
    24481 ttaaaggaaa atggcattat ttgtatcgag ccatcgatgc agatggttta accttggata
    24541 tttggttacg taaaaaacgg gacacacaag cagcctatgc ttttcttaag cggttagtga
    24601 agcagtttga tgaaccgaag gttgtagtca cagataaagc cccctctatt acaagtgcct
    24661 ttaagaaact aaaagaatac ggcttttatc aagggacaga acatcgtacc attaaatacc
    24721 tgaataattt gattgaacaa gactatcgtc cagtaaagag acgcaataaa ttctatcgaa
    24781 gtttacgcac tgcctctacc acgattaaag gcatggaagc cattcgagga ttatataaga
    24841 aaacccgaaa agaaggcact ctcttcgggt tttcggtctg tactgaaatc aaggtattat
    24901 tgggaatccc agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt
    24961 gcaacagaac cagcgaagta ataaagtaag tacctggtct aaaaacggca ttacagagca
    25021 taaaggctat gacaaaaaag ttttatccat gtataagaac gtattttttg aaatgcttga
    25081 gcgaattatt caattagaaa acgaaaaaga atagaatcac aaatcacaag tgattaatca
    25141 caaatcactt gtgatttgtg attgttgatg ataaaataag agtaagaaga aatagaaaga
    25201 agtgagtgat tgtgggaaat ttaggcgcac aaaaagcaaa acgaaatgat acaccaatca
    25261 gtgcaaaaaa agatataatg ggagataaga cggttcgtgt tcgtgctgac ttgcaccata
    25321 tcataaaaat cgaaacagca aagaatggcg gaaacgtaaa agaagttatg gatcaagcct
    25381 tagaagaata tatacggaaa tatttacctg acaaacttta aaaggagtga aaatgaaatg
    25441 gcagttacgt atgaaaaaac atttgaaata gagatcatta acgaattatc ggcaagcgtt
    25501 tataatcgag tattaaacta tgttttgaac catgaattaa ataaaaatga ctctcaatta
    25561 ttggaagtca atttattaaa ccaattaaag cttgcaaaac gtgtaaatct ttttgattat
    25621 tctttagaag aattacaagc cgttcatgag tattggcggt caatgaatcg ttactcaaaa
    25681 caagttttga ataaagagaa agtggcttaa tatggcaaat atagtcaatt ttactgacaa
    25741 acaatttgag aatcgcttaa atgataattt agaagaattg attcaaggaa aaaaagcggt
    25801 tgaatcgcca accgcttttt tacttggtgg gcaaccaggg tcagggaaaa ccagtttgcg
    25861 atcagcaatt tttgaagaaa cacaagggaa tgttattgtc attgataatg atacctttaa
    25921 acaacagcac cctaattttg atgaactagt gaaactttat gaaaaagacg tagtaaaaca
    25981 cgttacccct tattctaatc gcatgacaga agcgatcata agccgtttga gcgatcaagg
    26041 gtataatttg gtgatcgaag gtacaggacg aacaacagac gttcctattc aaaccgcaac
    26101 aatgcttcaa gccaaaggtt atgaaacaaa aatgtatgtc atggcagtac ctaaaatcaa
    26161 ctcatattta ggaacaattg aacgatatga aaccatgtat gcagatgatc caatgacagc
    26221 cagggcaaca ccaaaacaag cgcatgatat tgttgtcaaa aacttaccga ccaatttaga
    26281 aacccttcat aaaacgggct tatttagcga tataaggcta tataacagag aaggagtaaa
    26341 actctattca agtttggaaa caccttctat tagtccaaaa gaaaccttag aaaaagaatt
    26401 gaatcgtaaa gtatcaggga aagaaattca accgacttta gaacgaatag agcaaaaaat
    26461 ggttctaaat aaacaccaag agacacctga atttaaagca attcaacaaa aattggaaag
    26521 cttgcagcca cctacaccac caatacccaa aacacctaaa cttccaggta tttaaacctt
    26581 aaaaaaggaa aagagtagtt accaaaaaac ggtaactact ctttttttat aaaaacattt
    26641 cctcatgttg gggtcccgag cgcctacgag gaatttgtat cgataagaaa tagatttaaa
    26701 aatttcgctg tttttttcta atttcatttt gaggtgaatt aattggtagt tattagaggt
    26761 gccctatacc taataattta tctacattcc ctttagtaac gtgtaacttt ccaaatttac
    26821 aaaagcgact catagaatta tttcctcccg ttaaataata gataactatt aaaaatagac
    26881 aatacttgct cataagtaac ggtacttaaa ttgtttactt tggcgtgttt cattgcttga
    26941 tgaaactgat ttttagtaaa cagttgacga tattctcgat tgacccattt tgaaacaaag
    27001 tacgtatata gcttccaata tttatctgga acatctgtgg tatggcgggt aagttttatt
    27061 aagacactgt ttacttttgg tttaggatga aagcattccg ctggcagctt aagcaattgc
    27121 tgaatcgaga cttgagtgtg caagagcaac cctagtgttc ggtgaatatc caaggtacgc
    27181 ttgtagaatc cttcttcaac aatcagatag atgtcagacg catggctttc aaaaaccact
    27241 tttttaataa tttgtgtgct taaatggtaa ggaatactcc caacaatttt atacctctgt
    27301 ttgttaggga attgaaactg tagaatatct tggtgaatta aagtgacacg aatgttcagt
    27361 tttaattttt ctgacgataa gttgaataga tgactgtcta attcaataga cgttacctgt
    27421 ttacttattt tagccagttt cgtcgttaaa tgccctttac ctgttccaat ttcgtaaacg
    27481 gtatcggttt cttttaaatt caattgtttt attatttggt tgagtacttt ttcactcgtt
    27541 aaaaagtttt gagaatattt tatatttttg ttcatgttat cactcctgaa gtgattacat
    27601 ctataaacaa atacagaagt taaacgattt gtttgtaatt ttagtta
//
