LOCUS       NZ_LR135300            28557 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Enterococcus faecium isolate E7429 plasmid 4.
ACCESSION   NZ_LR135300
VERSION     NZ_LR135300.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA4885211
            Assembly: GCF_900639465.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28557)
  AUTHORS   Arredondo-Alonso,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) UNIVERSITY MEDICAL CENTER UTRECHT,
            Heidelberglaan 100, 3584 CX Utrecht, Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 02:59:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,289
            CDSs (total)                      :: 3,202
            Genes (coding)                    :: 3,086
            CDSs (with protein)               :: 3,086
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 44 of 116
            Pseudo Genes (incomplete)         :: 73 of 116
            Pseudo Genes (internal stop)      :: 24 of 116
            Pseudo Genes (multiple problems)  :: 20 of 116
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR135300.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..28557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /isolate="E7429"
                     /db_xref="taxon:1352"
                     /plasmid="4"
     gene            complement(<1..294)
                     /locus_tag="EQB73_RS16745"
     CDS             complement(<1..294)
                     /locus_tag="EQB73_RS16745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_197724956.1"
                     /translation="MTEKNIMVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSS
                     YEVQVSHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNID"
                     /name="recombinase family protein"
     gene            complement(296..712)
                     /locus_tag="EQB73_RS16750"
     CDS             complement(296..712)
                     /locus_tag="EQB73_RS16750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WP_000323438.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQA
                     GIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFTSP
                     PPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
                     /name="recombinase"
     gene            complement(713..1210)
                     /locus_tag="EQB73_RS17590"
     CDS             complement(713..1210)
                     /locus_tag="EQB73_RS17590"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="WP_002327635.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDRE
                     RMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSA
                     SGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKV
                     VR"
                     /name="DNA recombinase"
     gene            complement(<1521..2198)
                     /locus_tag="EQB73_RS16760"
                     /pseudo=""
     CDS             complement(<1521..2198)
                     /locus_tag="EQB73_RS16760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /name="DNA topoisomerase"
     gene            complement(2214..2816)
                     /locus_tag="EQB73_RS16765"
     CDS             complement(2214..2816)
                     /locus_tag="EQB73_RS16765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001062586.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQLQ
                     AMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENLRR
                     LINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAFDLF
                     LNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
                     /name="recombinase family protein"
     gene            complement(2830..3000)
                     /locus_tag="EQB73_RS17400"
     CDS             complement(2830..3000)
                     /locus_tag="EQB73_RS17400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000713595.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKVD
                     IADWLLQPREF"
                     /name="hypothetical protein"
     gene            complement(3322..4281)
                     /locus_tag="EQB73_RS16770"
     CDS             complement(3322..4281)
                     /locus_tag="EQB73_RS16770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="WP_002324287.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNKF
                     KQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVSCG
                     MRTLYRLFSKGIFDIDTLPMRGKRKPNGHQEKRGKQQYQRSIHDRSDNYPDFNSEFGHL
                     EGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFKSITF
                     DCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRKVNQTF
                     ISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
                     /name="IS30-like element IS6770 family transposase"
     gene            complement(4462..5142)
                     /locus_tag="EQB73_RS16775"
     CDS             complement(4462..5142)
                     /locus_tag="EQB73_RS16775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001067799.1"
                     /translation="MNPFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(5575..5787)
                     /locus_tag="EQB73_RS16780"
     CDS             complement(5575..5787)
                     /locus_tag="EQB73_RS16780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002324171.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIEY
                     RTEYLELTNQTDFLLIRKQQEQEKN"
                     /name="hypothetical protein"
     gene            complement(5808..6659)
                     /locus_tag="EQB73_RS16785"
     CDS             complement(5808..6659)
                     /locus_tag="EQB73_RS16785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002287227.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            complement(6760..7056)
                     /locus_tag="EQB73_RS16790"
     CDS             complement(6760..7056)
                     /locus_tag="EQB73_RS16790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(7191..8684)
                     /locus_tag="EQB73_RS16795"
     CDS             complement(7191..8684)
                     /locus_tag="EQB73_RS16795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            9296..10249
                     /locus_tag="EQB73_RS16800"
     CDS             9296..10249
                     /locus_tag="EQB73_RS16800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            10221..10496
                     /gene="prgO"
                     /locus_tag="EQB73_RS16805"
     CDS             10221..10496
                     /gene="prgO"
                     /locus_tag="EQB73_RS16805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            complement(11400..11570)
                     /locus_tag="EQB73_RS17405"
     CDS             complement(11400..11570)
                     /locus_tag="EQB73_RS17405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_073490843.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHKYEYYIGY"
                     /name="hypothetical protein"
     gene            complement(11567..11917)
                     /locus_tag="EQB73_RS16810"
     CDS             complement(11567..11917)
                     /locus_tag="EQB73_RS16810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002326767.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTEE
                     VAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIRHI
                     EFYQDNKWGRLE"
                     /name="hypothetical protein"
     gene            complement(11910..13235)
                     /locus_tag="EQB73_RS16815"
     CDS             complement(11910..13235)
                     /locus_tag="EQB73_RS16815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_002342448.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLATVG
                     VGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRLNQIG
                     IMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
                     /name="Y-family DNA polymerase"
     gene            13752..14567
                     /locus_tag="EQB73_RS16820"
     CDS             13752..14567
                     /locus_tag="EQB73_RS16820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_002326780.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELEK
                     YLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIARI
                     DDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEADENY
                     NVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDLEALL
                     SANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
                     /name="helix-turn-helix domain-containing protein"
     gene            14693..14950
                     /locus_tag="EQB73_RS16825"
     CDS             14693..14950
                     /locus_tag="EQB73_RS16825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002326781.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIFM
                     IVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
                     /name="hypothetical protein"
     gene            complement(15202..15774)
                     /locus_tag="EQB73_RS16830"
     CDS             complement(15202..15774)
                     /locus_tag="EQB73_RS16830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(15790..16395)
                     /locus_tag="EQB73_RS16835"
     CDS             complement(15790..16395)
                     /locus_tag="EQB73_RS16835"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            complement(16796..>17365)
                     /locus_tag="EQB73_RS16840"
                     /pseudo=""
     CDS             complement(16796..>17365)
                     /locus_tag="EQB73_RS16840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769338.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /name="FtsX-like permease family protein"
     gene            complement(17417..18097)
                     /locus_tag="EQB73_RS16845"
     CDS             complement(17417..18097)
                     /locus_tag="EQB73_RS16845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001067799.1"
                     /translation="MNPFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            18244..18327
                     /locus_tag="EQB73_RS16850"
     CDS             18244..18327
                     /locus_tag="EQB73_RS16850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            18452..19189
                     /gene="erm(B)"
                     /locus_tag="EQB73_RS16855"
     ARG             18453..19186
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(19452..20315)
                     /locus_tag="EQB73_RS16860"
     CDS             complement(19452..20315)
                     /locus_tag="EQB73_RS16860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016301 - kinase activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="WP_074394525.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGSG
                     KTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEALIS
                     RLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYETMY
                     ADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISP
                     KETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTPPIPKT
                     PKLPGI"
                     /name="zeta toxin family protein"
     gene            complement(20317..20589)
                     /locus_tag="EQB73_RS16865"
     CDS             complement(20317..20589)
                     /locus_tag="EQB73_RS16865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="WP_002331065.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEVN
                     LLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
                     /name="antitoxin"
     gene            complement(20606..20815)
                     /locus_tag="EQB73_RS16870"
     CDS             complement(20606..20815)
                     /locus_tag="EQB73_RS16870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="WP_000527318.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAKN
                     GGNVKEVMDQALEEYIRKYLPDKL"
                     /name="peptide-binding protein"
     gene            complement(20914..21810)
                     /locus_tag="EQB73_RS16875"
     CDS             complement(20914..21810)
                     /locus_tag="EQB73_RS16875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_002334978.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYFK
                     GGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGN
                     LASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTV
                     PTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLV
                     DTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYEN
                     VFFEMIERIIQLENEKE"
                     /name="AAA family ATPase"
     gene            complement(<21980..22084)
                     /locus_tag="EQB73_RS17770"
                     /pseudo=""
     CDS             complement(<21980..22084)
                     /locus_tag="EQB73_RS17770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636359.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(22108..22680)
                     /locus_tag="EQB73_RS16885"
     CDS             complement(22108..22680)
                     /locus_tag="EQB73_RS16885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="WP_001079938.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEE
                     AGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYK
                     IKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGG
                     QEPESRMIEPISLGFYEQNWYLIGFAG"
                     /name="HTH domain-containing protein"
     gene            complement(22956..23750)
                     /gene="aph(3')-IIIa"
                     /locus_tag="EQB73_RS16895"
     ARG             complement(22960..23750)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(23843..24385)
                     /gene="sat4"
                     /locus_tag="EQB73_RS16900"
     ARG             complement(23847..24385)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(24382..25290)
                     /locus_tag="EQB73_RS16905"
     CDS             complement(24382..25290)
                     /locus_tag="EQB73_RS16905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="WP_001255866.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDI
                     TYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLL
                     PLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPY
                     VIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLW
                     EKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKY
                     TGKTGCLDSTYAADIEERREQ"
                     /name="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
     gene            complement(25323..26057)
                     /locus_tag="EQB73_RS16910"
     CDS             complement(25323..26057)
                     /locus_tag="EQB73_RS16910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            complement(26038..26907)
                     /locus_tag="EQB73_RS16915"
     CDS             complement(26038..26907)
                     /locus_tag="EQB73_RS16915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_060763469.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIYY
                     NSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIKRV
                     EQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIYPTA
                     LKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYCINEK
                     KAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            complement(26922..27146)
                     /locus_tag="EQB73_RS16920"
     CDS             complement(26922..27146)
                     /locus_tag="EQB73_RS16920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000205227.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLDE
                     LKAIADVLGVKFVQAFILPDGEEIKISNE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(27289..>28557)
                     /locus_tag="EQB73_RS16925"
     CDS             complement(27289..>28557)
                     /locus_tag="EQB73_RS16925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_164857724.1"
                     /translation="MVITKSISRFARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKG
                     EVLLTIMASLAQQESQSLSQNVKLGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEE
                     AEIIKRIYREYLEGQSLVGIGRALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQ
                     KTVTVDFLTKKRVKNEGHVPQYYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKR
                     IYSSKYALSAITFCGDCGDIYRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDEL
                     YGAVMTAINKLLAGGNNMIKTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKG
                     QDYDHLADEIDELRDKRQILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKI
                     IQSVTVYEGHFVIAFKSGIEMEI"
                     /name="recombinase family protein"
     ARG             complement(24386..25290)
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             18453..19189
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     ARG             complement(23844..24385)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             complement(24383..25290)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="109.42"
     Typing          complement(7192..8684)
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtcgatgtta ccgtccatac actctgcaat catgcgatta aattcgtcac gctttttagt
       61 gttcgtacca gagataccat catctgcaaa gatgccagca aactcccatt cattattttt
      121 ctttataaac tctgtatagt gtgagacctg aacctcatag ctagaatttt gttcttctgt
      181 ttctgtagaa acacggcaat aggcagcaac acgaagtttc tttatctttt cttttgcggc
      241 tgtacttcct actcttttac gagcaggaat aaccattata tttttctctg tcactttatt
      301 cctcgctttc tatcagactg tataagtatt ctgctcgttc aaaaggatcc actggcatct
      361 tattatctgc ctttttcatt ttgaatcgtt ctttgggagg gggagaggtg aaagcggcaa
      421 gctctaccac tcgtcctaaa tcctttgcac gtttatctct aacttcttca gctttatcaa
      481 atatctcttt atcaataatt gctggatacg tatcatttcc aaggtagttg acgtttttca
      541 aaatgcgccc catcacagaa tgtgtctttt caatacctgc ctgttcgcca gccactgtaa
      601 gggatagtcc tgatatgtat ttctcaaaga atacctttac ttgacctgct gccttttcat
      661 cgacagtaac cactccatct tgaattttgt atccatatgg aatatatgcc atttatctca
      721 ccaccttttc tttcagggaa agaccgcatt tcaaattgaa tgtcagctca tccctggaat
      781 ttacaatgat gttcactaca aattcttcaa atagttcttc cgtgtagtca ccattaaaat
      841 tatctgctga cacataatta atgaggtcct ttatctcgtt tgctcgcaaa accccactcg
      901 cagagttcgt taccaggttt gttttttcgg tagtaagatt tttaatctca ctatctaaaa
      961 catttcgttc ctgattaaaa agagcaggtt ctaggaaacc tttggacatc agtgcaataa
     1021 gggtattgcg ttcttccaat agttgctcca ttagcttatc aatagcgtcc attctttcac
     1081 ggtcgctttc ttcatcgatt tggctaactg acttgaaaag tggttctagg attagcttat
     1141 gactgaaagc aagcttattc atcatggttg tcaatgtggc tttgatttcc ccatctcgca
     1201 aaaacaacat ggagcaactt tctttatctt cgatactatc tcaacatgtg tcgtggataa
     1261 ggtaagtatg taaaatggta tgtggaacat agtgatttgc tgtaaatgat ttgctaacta
     1321 ctttagttct ttatacaaag tataaatcgg atattttatt attttttctt ttatatcttc
     1381 tgagattagg tcaaagtatt tgtccgctaa atcagaaagg ggttcttttt tcatcaccta
     1441 atgggtgatg aagcagaata ctttaaagac tattaaatca atgttaggaa agactattag
     1501 taaaactatg aattattcag gaaaaaaggt tcttttttaa agttttctat tgcttcctgg
     1561 cgttgataaa tgagatataa agtcggtgtt tgtacacgtc ctaatgaaaa tgtaccttgt
     1621 acgccttttt gttgtaaatt caaggtatat aaagggcttg cgttcatgcc gatcaaccaa
     1681 tcggcaattt ggcgtgtttg cgcttcttga taaaagggat agtaattcat tcctggttgc
     1741 aaattttgaa aaccgcttcg gatcacatct ttttctaagc tattgatcca taatctttta
     1801 tacgttttat ctttagaaaa ggcatttgct ttatggataa tcgaccaggc gatattttca
     1861 ccttctctgt cgctatctgt tgcgacaata attgtatttg cctttttgag aagttcagca
     1921 acaattttaa actgctttcc cttatctttt gcaacttcaa aatcgtatcg atcaggaaaa
     1981 atcggcaaag attcaagttt ccagttctgc cacttttcgt tataatgacc tggttctgct
     2041 aattcgacta aatgcccaaa accaaaggtg ataaacgttt catctgtaaa tagtgggtct
     2101 ttgatctcaa aataaccgtc ttttttggtg ctttgtttta aagcacttgc gtaggctaat
     2161 gcctggcttg gtttttcagc taaaataacc gtactcatta actatccctc ttttcattgt
     2221 ttttttcttt gatctactgt cacgttgtat cttgatcgat accttctaaa cgttcggcga
     2281 ttaattccag tttgttcttc aacttcttta tcggaacaac cattcaaaaa taaatcgaaa
     2341 gcgtgttgta aacgtggatc attttctttg aatttaggtt gtcgcccttt gaattttcct
     2401 tttttcttag caatttcaat tccttgggct tggcgttctt taattcgttt gcgttcagat
     2461 tccgcttggt acttatacaa ttcaatcact aaattattaa tcagccgtct taaattttca
     2521 tcttcaatac cattcattga gggtaaattt aagacttcca gggttgcccc cttaatttga
     2581 atttgattca tcaattctgt taattcttta ttatttcgtc ctaatcgatc taattcagta
     2641 acaacaacta tatccccttc acgaatatag ttaagcatag cttgtaattg tgggcgttcg
     2701 accgattgac cgcttaattt gtctgaaaag accttagaaa cgccctctaa cgctttcagt
     2761 tgtctatcta agttctgttc tttgctactg acacgtgcat aaccaatttt agccattttc
     2821 aaccaacctc taaaattctc tcggttgcaa taaccaatca gctatatcta ctttttcaat
     2881 ttcaaattgc ttatcagaaa ttgtcttttc gtaagcgata aaatcttgcg catattgttg
     2941 ctcattaaaa atagccacca cttcgtcatt ttctaaaact cgataaataa attttttcat
     3001 tttactcctc ctattatgcc caacttaaat gacctattca ccaagtcaat tatactgcta
     3061 aaaccatatt aggacaaata agtatactct attgacctta aaaagatagc aacttaaaag
     3121 atcaagtgtt cgcttcgctc tcactgcccc tcgacgtttt agtagccttt ccctcacttc
     3181 gttcagtcca agccaactaa aagttttcgg gctactctct ccttctcccc ctaataatta
     3241 attaaaatct tactctctat atttctgcta atcattcact aaacagcaca gaaaaacaaa
     3301 cacgtatcat agtatgattt gtcaaattaa gctagaataa aatgcttctt gtacatagct
     3361 caaaaatatt tcgattggtg ttctgtaatt caatgatttt cttggaatat gattacgttg
     3421 attgctgaca ctggaaataa atgtctgatt cacttttcta aaatccattg atttcggcag
     3481 tccattacga cgcagaatcc cgttagaatt ctcgtttaat gggcgttgag aaggtgttcc
     3541 agggtccgca aaatatatat caatatcatg ttggttacta atggctttcc agttagaaaa
     3601 ttcttttcca cagtcaaacg taatagattt aaagaagttt ttagggaagc gagaaaacca
     3661 ttgattaagg gcagtttcaa tatctaatgc cttacggccg ttgggtttaa tcgtgataat
     3721 gactttagat aatctttcaa ctaaagtaat gacggcactt ttatgatgaa tgccaacgat
     3781 cgtatcacct tcaaggtgac caaactcaga attgaaatca ggataattat cagatcgatc
     3841 atggattgag cgctgatact gttgttttcc ccgtttttcc tgatggccat tgggttttct
     3901 tttacctctc atcggtagtg tgtcaatatc aaatattcct ttagaaaata aacgataaag
     3961 tgttctcata ccgcatgaaa cagacctttc ttttcgcccg ataatgacgt caggcgtcca
     4021 accaagagtg actttctctt taatgtaatc tacttcatga gcaggtaatt gaatgacttt
     4081 tctaccacat tttttcttat tttctttata ctggtgccaa taatcaagag cagtcttgcc
     4141 ttgcttgaac ttattgacta cattataaat agtttgtata gcacgtccca ttcggttagc
     4201 gatttcaacc ggcttattat gttgaagata atatgattct atcattgtca gttcgtctat
     4261 ggtaagatgt ttgtaggtca tttatggtta cactcctttg ttttctttcg tcggaaatac
     4321 aatttgagtg taccataaat gcctttttat ttttctaact taattttaca attcgcgtag
     4381 atataaatgt aatggcatag tgcgggtggt tctgttgcaa agttttaaat aaagaataaa
     4441 atcccttacg gtatctatga tttaagctgg gattcccaat aataccttga tttcagtaca
     4501 gaccgaaaac ccgaagagag tgccttcttt tcgggttttc ttatataatc ctcgaatggc
     4561 ttccatgcct ttaatcgtgg tagaggcagt gcgtaaactt cgatagaatt tattgcgtct
     4621 ctttactgga cgatggtctt gttcaatcaa attattcagg tatttaatgg tacgatgttc
     4681 tgttccttga taaaagccgt attcttttag tttcttaaag gcacttgtaa tagagggggc
     4741 tttatctgtg actacaacct tcggttcatc aaactgcttc actaaccgct taagaaaagc
     4801 ataggctgct tgtgtgtccc gttttttacg taaccaaata tccaaggtta aaccatctgc
     4861 atcgatggct cgatacaaat aatgccattt tcctttaatt ttgatgtacg tttcatccat
     4921 tttccatgaa taaaaggatt ttttattttt ctttttccaa atttgataga gtagtttgcc
     4981 atattcttgc acccaacgat aaatcgtcgt atgagaaacg ttaatgccac gatcatataa
     5041 gatttcttga acttcacgat agctaaggtt ataacgaaga tagtagccca cggctacaat
     5101 aatcacatcc tgctgaaatt gctttccttt aaaaggattc atcgtcattc ctcctgctat
     5161 ctttttctat tattctacct tatttgatag tagatttaaa actttgcaac agaaccgttc
     5221 gtcacatctt cgatcaattt ctcttacgat tttctcatcc acatttctta ttcttacttc
     5281 catattaatt cctccaattt aaaaaggata gcgaaaagga gcctatcctt tttgctatcc
     5341 tactaccctc cttttactat ccttcactat cctttcacta tcctattttt aaatattttg
     5401 ttcccacatt tatttttgag aaacgtaata ggcacagcct attggaacac tttttttaaa
     5461 aagtgttccc acgtttcctt atgctcttta caaataaagg cttttagaga cgttctggaa
     5521 ttttagattc cttgaattgt tcccattcat caatcaattg gctataagta gccattaatt
     5581 tttttcttgc tcttgttgct ttcgaatcaa caaaaaatca gtttgattcg ttaattctaa
     5641 atattctgtt cggtattcaa tgttcatcgt acccgtttta ctacatagta actgattatg
     5701 acgttctttc actttgaata actgctcctt ctttaaggtt tttaactcca tgccaactat
     5761 aagcacaatc ctgtatagag gaatcatttt caaacgattc tccataatta tttatctttc
     5821 attggaagtt ctaaatcact actgttccaa aaaatgtatg gtttgttttg acgaatatta
     5881 cttccatcta accacaattt tccgatgcca tatcgtaggc ttgcttcgac ttcataaaaa
     5941 ttgtagatct cttttcttcg atctattgct ttcatttcct ggccattttt taaaatagat
     6001 ctgatgccct taacagtaga ttcatggata ctcgtgtgaa cgatatccgt attgatcaat
     6061 tcgtcatatc ttccaaaatc aacattgtac tcataaccaa gaagtgtcgg aatcaggtca
     6121 atttcaattt ctttttcaat tgaacgttta ataagtttcg tggatacata cccgacaaaa
     6181 aagagaataa tacccacttc aaacaaatac atgtgtccat ttacaaagtg aataaacgtc
     6241 aataaaaaat ccttcactcc ttttgttgtt cttccagatt gttcaatttg ttttattaaa
     6301 gtcgctagaa ttgcatttac aacaattaaa tcgaataggc ttttgaaaag ttttcctgct
     6361 gttaattttt gcctggtaaa ttgcatgact aattgagtaa aaatagacaa tagcatgaca
     6421 aaaatcaacg tcattagcac tgtaaaaatg tctgatgctg caatcctatt gggatcattt
     6481 atcaagtaat aagccgttcc aaatactcca atcgagtaaa cggttaaatc aagaataagt
     6541 cgtgccccgt aactacaaag ttttcctaat ggccataatt gcaataccca aaatttcttt
     6601 cgtttgctat ttcttttcag aggaagccag gtgtgttcaa tccagtcgtc cgatttcatt
     6661 tcgatttctt ccctaaattc tttcctttaa cgttttcctt tgctacttta gcagcgatag
     6721 gttgctcaat gaaccaattt tttaagtaaa taaaaactac tactggatat acttcttcct
     6781 ttttcttaac tcgttagcta ttttatactc aatatactcc tgctctaaca cacacaaaca
     6841 atcatatacc tgatccatag tctccccaga agctaaggac aacccatgaa gaaactcaat
     6901 cggcaaagaa gcaactgttt tttccctggt aacccaagaa gacaaagtcc cctgcttaaa
     6961 accataaagc tcacagaaca cttccacaga taatcccaaa cgaccaatga taaacacatt
     7021 aacaggatgt gaatagacat aattttttaa cgacatacaa cttcctccat gatacataag
     7081 actgcatacg cagttataag tataccacct acacgtagct aggcaaaggg agcaacacct
     7141 acagaagtat catagatata ttgtataagg caatttgcac cttttatttt tcaacctgta
     7201 tctacttcaa aaagattcac ttctttaaga gggttcaagg gggttgataa ttgtctaaat
     7261 gtctcttcta ctaagctctc gttgagtcca aatacctctg tgatccttgt tgaataatct
     7321 agtctctttt ctttacttag ttgaataacc ctcgcgaaca acgttttgac tgaagcaatg
     7381 atcattccgc catttcttcc tcgtgttacc ttgtagaaga ctttattctc ctctcgtaac
     7441 tcatttaaga tcttatcaag tgttcgcttg ggcatcgtta gttgtgaagc caattctttt
     7501 tttgacaggt tcaaataagg ctcactagca agactttttt cgcttagata agccaataga
     7561 tcttctttcc attcattttt atgactatat tttctttgat ctcgtggctt tttaaatttc
     7621 caccagccac gtcgttgaat gaacagatca ttatttttta aggttggtga aacccattgc
     7681 tggcacaatt caataatgaa ttctctgctt gctgcttgat aattaccaga ataagcacta
     7741 cgtacaatct ttactaattc tgcttcagat agcggttcct gtaaccgttc gttgaatgtg
     7801 aacatattgt attcgcaagt atccaatgca taacctgaag agtaataagc taaagaaagc
     7861 gtgaaaatca cattatttcg accaagacgt ccttctccgc cgacgatgtt tgctttatga
     7921 agtaacatat cgaaccacgg ttcatctact tgacgaattt cttttttctc aggaaagaca
     7981 attagttttc gttctcgatc ttcttttgtt ttttgatctg attcaagctt catcgaccat
     8041 tgaatccagt cagcaaaaga atactgatag ttcatttctt taaaaacaat attattttct
     8101 tgtgggaatc gagcaattcc gaagtggtta catcctagat ccactccgga caatttttca
     8161 gccaactgta gacgaattgt ttttgaaatt ttttttgcta catcgatcac cttgaaattg
     8221 cttttctttg tgacatagcc tggtgtcttt agtacaaaat aaacttgata accatgatct
     8281 gattctaaaa ttagcgttgg catgtagccc acttgatcta aacaggctaa aataatttcg
     8341 ccttgatggt tctcttttga atcgatatca actacaaatg tgttgatttg acttaagttt
     8401 ttctcagaat gacctttaac cactgttcga taatcatccg cataagtacc aaagcgatag
     8461 gtattaggtg tccaatgcgt tagtttcttt tcgttctcta aaatagcttc ttccgaagta
     8521 atgaccatac cacgcccaac attcattaat tgcttgctac ggtacgcaaa gatagcacca
     8581 ctcctactgg aatcaatatg acctgcaggt ttcatggtgc tgtttcgata tttgtatgta
     8641 cgtaagccgt ttttaagaat agctgaataa atttcgctca acatcgattg taacgtcctt
     8701 tctcaaacaa aaagagaaca cagtttagct ttaatctcag ccatagtatg tgttctctct
     8761 tcagtgttta agaatattta atttaagtac actaaataaa cgttcttctg ttgagttgct
     8821 cgcctttttt tggtagaata aaggcaatcg gaaaaggtat ccgatcaact tttaatataa
     8881 gtagttggta gctacttaca tattcttgag acgagcgtga acacatgtcc taaccatgtg
     8941 attcagaaat aattgattct gctaaaatca attatttccg tctctttttt ttatgtaatt
     9001 tttctgttta aagagtacca ctgcttttgc tactttgtaa atagtgaatt atctgtggtt
     9061 tctatagaat taagtttacc tcttttcact ctaaattgtc aacgcaaaac gcacaaatat
     9121 attttgacat tttgaatata tctgatatac tgaatatagc aaatatattt agtatatcca
     9181 ctatattcct tataaagtct gaattcttat caatttggag tatattagat atatcgaata
     9241 tattaagtat atgaagtata ctaaatatat ttagtatagg aaattggagg gaactatgga
     9301 aaacttacgg actgcattta aaacatcaga taaactagga aaagttgtaa tgcttacagg
     9361 tagaaaaggc ggcattggta agactacaga caatgattta ttagcgattg tttctagtca
     9421 actttttgaa aaagacgtgt tgctaattga ttatgaccaa caaagaaata ctacttccaa
     9481 cattggatca acgtatcaaa ttactagctt tgatcgatcc atgtctgcag caatcaaaaa
     9541 aggggactgg gtttcaggta ttactcaagt aagtccacat ttatatatta tggctggctc
     9601 tcctggatct gaagaactta atgaatactt gtccgaaaaa tatcctgatc gtcgtaagag
     9661 atcattggcc ttcattaaac ctttagaaga attgagaaaa aatttcgatt atatctttat
     9721 cgactgccca ccatcaacag ataatgtggt tcgtgcattc ttaactgctg cagattatat
     9781 tattgcaatg caagaattaa aacggtacgc aatggaagga acagaagatt ttattaataa
     9841 agttttagtt ccgattgtca cgaattttga agagtctcat cttcaaatca ttggaatttt
     9901 gcctgttctt ttctcagtgc gacgttcctc tcaacacgca aactatcaaa aaacaattga
     9961 taagtatggt gaatcaaaca tttttaaaag cattgttaaa ggctcggatc ggttagaaat
    10021 gtatggtgag aatggtatcc aattaaatga ttatgtagat cgaagatggt gggctatttt
    10081 tgcagacatc tttacagaat tagaagaaag aattgaatac tatgaacaac atggtgatat
    10141 tgaaggattt gattatacac ctaaatatgc tgactcaatg gccaatcata tcctacctct
    10201 tggaaaggag attaaactaa atggcattat taccaacgaa caaagataag aagaaaattg
    10261 gtgctgaaga tatttcaatt aaagatgata ttaatgtcga gttaggggaa cgaaagtaca
    10321 ctgcgaaaga aagaaaacca gttcaagtag atcctcccgt actaaaaacc attcgggatc
    10381 ttagttatgc aaaagatatt cctatgtatg aaatagtcaa acttgcaatg gacgcctatg
    10441 ttgatacttt aaacgacgag gaacggatta tatataatag acgatcaaaa gattaaaata
    10501 tagtaagtat actagatata gtaaatatat ttagtatact tactatattt ttagctttat
    10561 taatcctaat ccttcaaaat atgtgtattg tttgggggta tacaacattc acaaatttta
    10621 ttgtttctag tttttactat actaaatata tttaatatag tgagtatagt aaatatattg
    10681 gtttttatct acaggtaatg gtggttttaa caaacatata gttacagtta ctgaagaaca
    10741 gtccgttagt cagcaggagt aagtaataaa tcgtttgtga gacactattt tgattgatac
    10801 gacctctaac catgtgtttg tttcatttat gttataataa gaatgtaagc atattaaaca
    10861 gcaaactatc acagcagcac tagactcaat caaatgaagg gggatggtgc taatgaaaaa
    10921 actactagca atttccctta tcctaaaaag gagaattaat agtgtcaaaa gaacctatgt
    10981 ccgcatggat gcagctcgct cttagcatca taaagctgat ctctaatttt gtggctttag
    11041 acaatagagc aaaggttcta actacgcaat gtttagtaat acttacttgt agcctactgg
    11101 ttgtaatagt atttctttta cttgcgttat tcgtagtaca ccttttgttt ttttaaaaca
    11161 aaagaagctt attcaactat atttagctga ataagctggt ctcaatgtta aatcaagttt
    11221 gttggacggg tttaacattg ctttctagtg ctattttagt tagctctagt atgcttcaag
    11281 ctagttacaa cgtcctaagg ttgtaactag tttttttata ttttttaatt acctataggt
    11341 aattttatca gaattgatac aaaatgtaaa acataaaaga aatataattt tattgcactt
    11401 taatagccaa tatagtattc gtatttatgg tatcctgctg cagcttctac atagaaagag
    11461 aagcgttcaa caccaacctc atttatcaaa cgctggccat aaccccaaat ctcttctgat
    11521 agctgatcaa aggttatata ctttagctca tattgctgga taatgttcat tctaatcgac
    11581 cccatttatt atcctggtaa aattcgatat gacgtatttc gtcgtagtga actttgtttt
    11641 ttccaacgta gatccccagc tcatcactac ctaagatctt gctaacaata tcttctggat
    11701 agtatccttc agcgtttcgt tcttcttttt gaatacatac tgatctattt tttatgactg
    11761 cagcgttcaa tacttccgca acctcttcag tcgtcatttg ttcttttgcc aaattttgat
    11821 tggctcgttg ttcattgtcg gcatcaattt tttcagtatg atcagataaa taaaaacctg
    11881 cccactttaa acgtccacga tcattataat caatcatttt taagccctcc tgcgccgcct
    11941 gcatggccac caaccaatgt acttctagta atactacgag cgccttctaa catagaagaa
    12001 gcatgtacaa tcgacgtaaa accatatttt tgccgaatct tgtcaataat tttatctaaa
    12061 ttttcttcgt caatttgctt ttgtggatca ctaaataaat ccagctgaag cgaatcagtg
    12121 tacacaagct tgctataggt tattccaacg tgccttactt cttgtccttc ataatactta
    12181 tcaaacaaga aaagacagta attctgcaat tcctttgtat tatctgttat agggatcttc
    12241 atctggtgtg aaaaacctgg tctcgtttct aagatcgacg tgccaatgta taaatggaca
    12301 caacctgttt tacagttatg ttgcctgata cgaatagcta cttgttccgc catttctttt
    12361 accaccagtt cgatttcatt tctcctggta taatctcgtg gtaacacttg tgaattacca
    12421 tatgattttt cctttgtcgg ttctggtggg atcgctatat ctgttcgatc gatcccgttc
    12481 gcatgaaaat acagctgtaa gccaatcaca cctaaatggc tcttaatagt gtatggattc
    12541 caattagcta agtctttaat actcatgata ccaatttggt tgagtctttt tttcattcga
    12601 gatccaatac cccaaaggtc tgtcatttca ggaatattcc atactttatc aggaacattt
    12661 tgatacgtcc attcagcaag gaatccatca ttatgttttg cttcattgtc taaagcaagt
    12721 ttagctaata agggattatc tccgacacct actgtagcaa gcaatcctag ctcttcttta
    12781 atattctcct ggatcatttg agccagcttc tttctccgtt gacttcttgt tccttcagtc
    12841 gtaaaaagat tcattgatct ggtcactttt aagatcgatt catcgatcga gtaaatcaat
    12901 aaatcttcgt ctgctacata ccttctgaaa atattgttta cctgcatatt tcgcttaata
    12961 tagagattca tgcgtggtgg aacgacatgt aacgttttag gaaaaggttg cggtagatct
    13021 cgtggtcgac tgacattaga aataccgtac ttcttctttg cagctggtga agaagctaaa
    13081 atcaaccctg atcctgtatt atccgctcga ctcatgacga ctaattcagt cgttaatgga
    13141 tctaaattcc tttctataca ttcgacactt gcgtaaaagc ttttcatatc gatcaaaaag
    13201 taatcattta ctggctcttt tgaataatcc atcataaata acactccatt cttccacatt
    13261 atacaaacat acgttcgttt ttgtaaagaa gaatcgatta aatgtacaaa aaaagaagca
    13321 taggtaagtt atttccctac ttcttctgtt gatttgtaaa atcaacacat tgtatcactt
    13381 tattaaatgg atatttacta ttagtcttgt gaaaatttga aaataagtgt cgtattatcc
    13441 agttttgctt agttatatta gaaaaaaata agaaattcaa aaaagaaaaa actttcctta
    13501 aaaacaaaaa ataggagtat tcagtttctt aatagttttg taatagttgt atgtagaagt
    13561 tttcttaata gtttttgtaa taatttatta atcgtagttt atataactta tttgtaagtg
    13621 actagagaat taaataaaaa ataattacta tctagtacga aattaattac ataggataat
    13681 atattaaggt gctggactac aagtaaaaaa tactgtatga tcatgacaga ttcaagaaag
    13741 gagcaataag attggttaag atagcaggac tttctaaagg tggaaaaacc gtttcacaac
    13801 tttataaaca aaactacaga gactggagac agttcagaaa aaacattaag gattcttact
    13861 ttattctacc aacagaactt gaaaaatatt taccgaataa caaagctatt aatttatatc
    13921 tgtattactg ttttaaggca aagaatgaag gcggggattc ctggcattcg gtcaatacca
    13981 tagcagagtc tctaggagtg acaactaaaa ctataaacac ctggaataaa accttagttg
    14041 atttaggtat gattgcacgt atagacgata accatctcag taaatcgaca attttacttc
    14101 ctctctctag ttactataaa ttagcccttg atagttcttt aaaggatgtt accgagagca
    14161 ctgtccatga aattgatggc aacttggttg cagtttatca tttgtttgaa tggagaaaaa
    14221 atgaggctga tgaaaattat aacgttcctt ataacacact ctgttgtgtt tttaaaagaa
    14281 aaacacaaaa agatactatc tataaattta tcttggtcca agatgagaaa ataagtaatt
    14341 tcgaattaag cactccttct agtaagattt atgacgatgc atatagattt gaatgtcaag
    14401 atctagaagc cctcctttcc gcaaataatc taaacaatat agaacatgaa aactttgttg
    14461 taaacactag atttaattta gtttctgaaa aggactcaga tttgttagat ttgctgatag
    14521 agcttactaa aaatctagat aagaaagaaa acattactgt actataacta gcatcggtcc
    14581 atcattaagt ttggactatt agaacacttg ctattacaga aaaaggtatg ctagccacgc
    14641 ttactattta ttggtatcaa acaagtatct taatttgaaa ggaagatgat ttatggctaa
    14701 tttatatata gagaacaaag gagacttgaa tgccattatt actttaatcg tagttatggt
    14761 aaaatcaata ggtaatatca caataggaat gctgtttatt atattagcag cagtgctgat
    14821 ttttatgata gttatttggt tcttaaatga aagatctaaa gacaatcaac accgtaggga
    14881 tatggagata aaatcaatag agtcaataga ttatttatcg ataataacac taaaaaagcc
    14941 acgttcctaa acgtgactta cgctgaacga tatgtgttgt ttggtagacg aacaaatcgt
    15001 tcattataaa tatatgatgg tatcctaata tagtaagcgt ggctagcata cctttaatta
    15061 ctttaccttt tacagttacc atacacattt tttgagcaga aatcaagtaa ataaaaaaat
    15121 attatatttc acaacatgct aatagactca tatctagaac gcattaagta tttacctgtc
    15181 tggttcgctg agacttcttt tttaactttc ttcaattttc ttctttattc taaaaagcgt
    15241 actgcgactg aaaccggtta tagcttcaac ttccttatac gatttacctg aagtaagcag
    15301 ttcatatgcg tgcctcttct tcggtgtgat tgttgctttc ggacgtcctt ctctgaaatt
    15361 aggattattc tttcttgcaa acatttttcc ttcttgggta cgttccacaa tcatatcacg
    15421 ttccatttct gctacactca acaacgtccg tgtcaccatt cgccccatgg acgtattttc
    15481 aatcgttcct agattcaaaa ccttgatcgt tacgttatca tcgagtaaag gttcaatgat
    15541 ctctaatgct tctctcgtgt tacgagcaaa tcgatcaagc ttcgtaacaa ctatttcatc
    15601 tccaggcttc agaccagcca acagctgatt gaattttggc cgatcccgtt ttgtacccgt
    15661 aaatttttct gaaaaaatat tcttcttctc tacgccgttc tcaagcaact gttgaatttg
    15721 ttcttttgta ctttgagaag cggttgagac acgtgcatat ccatatttcg tcatttggtc
    15781 cacctacttt tacaaatcat ctatcgtata ctcagaatac ccttcataga aatagctgac
    15841 atcgattcct ttcatatata actcgcgatc gtcaatttta tcagtcagag cattggaaat
    15901 tagatagcgt atttccaaat cgtttatggg acttcgctcc attgcagaaa gatagtctgc
    15961 tttatcgatt aagttccaat ctacaacttt ttgcaattct tcctttaaaa tgagatccag
    16021 ccaaattcta gtacttcggc catttccttc tcgaaatggg tgagcgatat tcatctccac
    16081 atatttcttg ataatctctt caaaagaagt ttgtggcatc tgatcaatat gctgtaacga
    16141 atgttctaaa tacataactg gtgcaaatcg aaaatttcct tttgcaatat tgaccgatcg
    16201 gatttttccg gcaaaatcgt aaatatccga aaatagaaat tcatgaattt cagataaacc
    16261 tttaaatgta ccaacttcga tttcatttat ttttccacaa tcgtacaatt ctttcgcttt
    16321 ttgtttactg agtttttctt caaccttagc caactcaact tgattggtta atcccaattt
    16381 attctctaaa atcatgcgaa atctccttaa ctttatgaca taagtttatg aaacactctc
    16441 aaccccatta tatcgcgatt ttgtttatgt gtcaaaaact attaagtttc tgacccccga
    16501 tagatttttc aagtgtctct attttgcaca gtctagttga cctttgatac acctctatat
    16561 ttatagagaa tctaaaacat caacatggca tactcaaaat tctaaatatt agggataaag
    16621 aattctccta tacaatcaaa aatttccttt atttcgaact ccggtcacct aactctattg
    16681 atctcttaca agccaaagaa tatctctata ctacaaagaa acaatagggt gcctggttgg
    16741 tctctttgtg ttttatttta gaatctagaa cgtaaatatt cttgtcattc tgattttatc
    16801 taagaatatc aattaaatct ttttttgcag cctctgaagc gggcattaca gaaaagacca
    16861 gtccaataac cgaagatacc ccaaccgcta gtaaaatagt aaatagatca agtgacacgt
    16921 ttacctttat caaagaacca acactataag caagagccat tcctaataaa tagccaatta
    16981 accctcctga aagagttaaa atcaaacctt ctaaaaggaa ctgcagcata atcgattttc
    17041 gagtagctcc tagggctctt cttataccga tctcttttgt tcgttcagat acagatatat
    17101 acatcatgtt cattacacct acccctgcga taaataaaga tatacctgct acagctgtta
    17161 taaaataagt gatcgtactg aggatttgac caattccttt cgttaacata gccgtatcta
    17221 acacttcata ttcccccaaa tgtttcaaac tacctttttc tttcaattgg tttatcactt
    17281 tagaggtcac cttgtcaggt tcaactcctt cctctaaagt taacgttaga gacgatgtat
    17341 ccttttcaga cttaaaataa taggttctgt tgcaaagttt taaataaaga ataaaatccc
    17401 ttacggtatc tatgatttaa gctgggattc ccaataatac cttgatttca gtacagaccg
    17461 aaaacccgaa gagagtgcct tcttttcggg ttttcttata taatcctcga atggcttcca
    17521 tgcctttaat cgtggtagag gcagtgcgta aacttcgata gaatttattg cgtctcttta
    17581 ctggacgatg gtcttgttca atcaaattat tcaggtattt aatggtacga tgttctgtcc
    17641 cttgataaaa gccgtattct tttagtttct taaaggcact tgtaatagag ggggctttat
    17701 ctgtgactac aaccttcggt tcatcaaact gcttcactaa ccgcttaaga aaagcatagg
    17761 ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa ggttaaacca tctgcatcga
    17821 tggctcgata caaataatgc cattttcctt taattttgat gtacgtttca tccattttcc
    17881 atgaataaaa ggatttttta tttttctttt tccaaatttg atagagtagt ttgccatatt
    17941 cttgcaccca acgataaatc gtcgtatgag aaacgttaat gccacgatca tataagattt
    18001 cttgaacttc acgatagcta aggttataac gaagatagta gcccacggct acaataatca
    18061 catcctgctg aaattgcttt cctttaaaag gattcatcgt cattcctcct gctatctttt
    18121 tctattattc taccttattt gatagtagat ttaaaacttt gcaacagaac caaaattttg
    18181 tataatagga attgaagtta aattagatgc taaaaatttg taattaagaa ggagggattc
    18241 gtcatgttgg tattccaaat gcgtaatgta gataaaacat ctaccgtttt gaaacagact
    18301 aaaaacagtg attacgcaga taaataaata cgttagatta attcctacca gtgactaatc
    18361 ttatgacttt ttaaacagat aactaaaatt acaaacaaat cgtttaactt ctgtatttat
    18421 ttatagatgt aatcacttca ggagtgatta catgaacaaa aatataaaat attctcaaaa
    18481 ctttttaacg agtgaaaaag tactcaacca aataataaaa caattgaatt taaaagaaac
    18541 cgataccgtt tacgaaattg gaacaggtaa agggcattta acgacgaaac tggctaaaat
    18601 aagtaaacag gtaacgtcta ttgaattaga cagtcatcta ttcaacttat cgtcagaaaa
    18661 attaaaactg aacactcgtg tcactttaat tcaccaagat attctacagt ttcaattccc
    18721 taacaaacag aggtataaaa ttgttgggaa tattccttac catttaagca cacaaattat
    18781 taaaaaagtg gtttttgaaa gccatgcgtc tgacatctat ctgattgttg aagaaggatt
    18841 ctacaagcgt accttggata ttcaccgaac actagggttg ctcttgcaca ctcaagtctc
    18901 gattcagcaa ttgcttaagc tgccagcgga atgctttcat cctaaaccaa aagtaaacag
    18961 tgtcttaata aaacttaccc gccataccac agatgttcca gataaatatt ggaagctata
    19021 tacgtacttt gtttcaaaat gggtcaatcg agaatatcgt caactgttta ctaaaaatca
    19081 gtttcatcaa gcaatgaaac acgccaaagt aaacaattta agtaccgtta cttatgagca
    19141 agtattgtct atttttaata gttatctatt atttaacggg aggaaataat tctatgagtc
    19201 gcttttgtaa atttggaaag ttacacgtta ctaaagggaa tgtagataaa ttattaggta
    19261 tagggcacct ctaataacta ccaattaatt cacctcaaaa tgaaattaga aaaaaacagc
    19321 gaaattttta aatctatttc ttatcgatac aaattcctcg taggcgctcg ggaccccaac
    19381 atgaggaaat gtttttataa aaaaagagta gttaccgttt tttggtaact actcttttcc
    19441 ttttttaagg tttaaatacc tggaagttta ggtgttttgg gtattggtgg tgtaggtagc
    19501 tgcaagcttt ccattttttg ttgaattgct ttaaattcag gggtttcttg gtgttgattt
    19561 tgaaccattt tttgctctat tctctccaaa gtcggttgaa tttctttccc tgatacttta
    19621 cgatttaatt ctctttctaa ggtctctttc ggactaatgg aaggcgtttc taagcttgaa
    19681 tagagtttca ctccttctct attgtaaagc cttatatcgc taaataagcc cgttttatga
    19741 agggtttcta aattggtcgg taagtttttg acaacaatat catgcgcttg ttttggtgtt
    19801 gccctagctg tcattggatc atctgcatac atggtttcat atcgttcaat cgttcctaag
    19861 tatgattcaa ttttcggtac tgccatgacg tatatttttg tttcataacc tttagattga
    19921 agcattgtgg ctgtttgaat gggaacgtct gttgttcgtc ctgttccttc aatcactaaa
    19981 ttatagcctt gatcgcttaa acggctaata agtgcttctg tcatgcgatt cgaataaggg
    20041 gtaacgtgtt ttactacgtc tttttcatag agtttcacta attcgtcaaa atttgggtgc
    20101 tgttgtttaa aggtatcatt atcaatgaca ataacattcc cttgtgtttc ttcaaaaatt
    20161 gctgatcgca aactggtttt ccctgaccct ggttgcccac caagtaaaaa agcggttggc
    20221 gattcaaccg ctagtctatt tttagttagt cgttcaacat tcttttctaa acgatcttca
    20281 aattgctttt cggtgaagtc agtaatattc gccatgttaa gccactttct ctttattcaa
    20341 aatttgtttt gaatattgat tcattgaccg ccaatactca tgaatagctt gtaattcttc
    20401 aaatggttgt tgaaataaat caacttcttg tgccacttct aattgattta aaagattcac
    20461 ttctagtaaa cgagtatttt tagtatctag ttcatgattc aaaacataat ttaatacccg
    20521 attataaaca cttgccgata actcattaat gatttcaatt tcaaatgttt tttcatacgt
    20581 aactgccatt tcattttcac tccttttaaa gtttgtcagg taaatatttc cgtatatatt
    20641 cttctaaggc ttgatccata acttctttta cgtttccgcc attctttgct gtttcgattt
    20701 ttatgatatg gtgcaagtcg gcacgaacac gaaccgtctt atcccccatt atatcttttt
    20761 ttgcgctgat tggcgtatca tttcgttttg ctttctgtgc gcctaaattt cccacgatcg
    20821 ctcacttctt tctatttctt cttactattt attttatcat cacctatcac aaatcacaag
    20881 tgatttgtga ttaatcactt gtgatttgtg attctattct ttttcatttt ctaattgaat
    20941 gattcgctca atcatttcaa aaaatacgtt ctcatacata gacaaaactt ttttgtcata
    21001 gcctttgtgt tctgtaatgc catttttaga ccaagtactt actttattac ttcgcttgat
    21061 aatatttcgg aaaaccaaat tatcctcttt atgttctttg tacagttctt ccaggtttga
    21121 ttttatcgtt gcgctgtccg tatcaactaa ataaggaaca aaaccaatca tatctagtcc
    21181 agggttaaac tgttcttgca aatcaatcaa ataggaaata tagttttgaa tgttgtttgt
    21241 actttcttct tctgcttgta aagggatcat aacgtaatca ctcgccacga ttgcattatt
    21301 tgtataaacg cttggcgttg gtacagtatc aataataata agatcatagt cactttttaa
    21361 aggtgctaaa agagtagcaa gcaatctact ttcattttca aacgtccatg agcgagttaa
    21421 ttttggcagt aacatcaaat caaacgtgcc agggatcaag tctaaattat cagtcaaatg
    21481 aataatagaa gaagccaagt ttccattttt caagccttca taaaaattga cacgtggcaa
    21541 ttctacctca aaagtttttg ctaagtcttt tgtcaatgtt gcctgtaagt ccttatcgat
    21601 cattaaaact tttaaattca atttgtctgt caagtaagca aacatagtcg ataatttgga
    21661 ctttccaaca ccacctttaa agtaattatt caagataata attgcttcat ttttattgtt
    21721 taaaatacgt cttaattctt caagtatttt tagtttttcc ttctccataa ctacgcccca
    21781 ttcttttttt gtatagtaat attgtatcat taagaatcac aaatcacaag tgatttgtga
    21841 ttaatcactt gtgatttgtg ataagtgatt tgtgattaat atataaaagc cctctttaaa
    21901 gggcttttat atttattttg agaaagatat aaaatcaata tatccctttt ccccaatttt
    21961 tacaacggca ttgtagggca tatagttttt tatatgaaag catttgtttt aatatttgtt
    22021 ccaaagagcc atcatggctt tgacagagct cttcttctat gcaaatgctt ttaatccgat
    22081 ccacacgaaa attcctatat tcatttctta gcctgcaaaa ccgattaagt accagttctg
    22141 ttcataaaac cccagtgata taggctctat cattctgctt tccggttctt gccctcctga
    22201 tgcaggatat tgaattgata ttaccctttt attgcagatt gcagtctgaa ttgctgcaat
    22261 aacgttatcc gccaatgtat ttttctgtcc agatgtgctg tacacgttaa tactgttctc
    22321 caactcctgt gcatagtttt tttcaccatg cttcaaaata gatttgattt tatacatagc
    22381 tgaatcaaaa tcctttataa atgattcatc tccatggcaa tttaaaaatt tccctgctgt
    22441 aatcaatgca cccacttccg ccgctgtaaa cattaccggc ggaagtagga agccctctac
    22501 aagaaaatat ccttttccgg cctcagatcc aattggtatt ccggcttctt caagtgtccg
    22561 gatatctctg taaactgtcc ttaagcttat attaaatcgc tgtgcaattt ctttggcagg
    22621 aattattttt tttgattgca gctgaataag aatagaggtt actctgttaa tcctgttcaa
    22681 attttattcc tcctctgtga cttccataaa aagtatatcc tatgcgttct taagctagct
    22741 gctgttagtg cttctcattg caccctggtt ataaaagcca tactcacaaa cctcttcacc
    22801 aaaactcttt acatctctaa tatagaactc tatctagcga acttttagaa aagatataaa
    22861 acatcagagt atggacagtt gcggatgtac ttcagaaaag attagatgtc taaaaagctt
    22921 gtagttaaag ctttttagac atctaaatct aggtactaaa acaattcatc cagtaaaata
    22981 taatatttta ttttctccca atcaggcttg atccccagta agtcaaaaaa tagctcgaca
    23041 tactgttctt ccccgatatc ctccctgatc gaccggacgc agaaggcaat gtcataccac
    23101 ttgtccgccc tgccgcttct cccaagatca ataaagccac ttactttgcc atctttcaca
    23161 aagatgttgc tgtctcccag gtcgccgtgg gaaaagacaa gttcctcttc gggcttttcc
    23221 gtctttaaaa aatcatacag ctcgcgcgga tctttaaatg gagtgtcttc ttcccagttt
    23281 tcgcaatcca catcggccag atcgttattc agtaagtaat ccaattcggc taagcggctg
    23341 tctaagctat tcgtataggg acaatccgat atgtcgatgg agtgaaagag cctgatgcac
    23401 tccgcataca gctcgataat cttttcaggg ctttgttcat cttcatactc ttccgagcaa
    23461 aggacgccat cggcctcact catgagcaga ttgctccagc catcatgccg ttcaaagtgc
    23521 aggacctttg gaacaggcag ctttccttcc agccatagca tcatgtcctt ttcccgttcc
    23581 acatcatagg tggtcccttt ataccggctg tccgtcattt ttaaatatag gttttcattt
    23641 tctcccacca gcttatatac cttagcagga gacattcctt ccgtatcttt tacgcagcgg
    23701 tatttttcga tcagtttttt caattccggt gatattctca ttttagccat ttattatttc
    23761 cttcctcttt tctacagtat ttaaagatac cccaagaagc taattataac aagacgaact
    23821 ccaattcact gttccttgca ttctaaaacc ttaaatacca gaaaacagct ttttcaaagt
    23881 tgttttcaaa gttggcgtat aacatagtat cgacggagcc gattttgaaa ccacaattat
    23941 gatagaattt acaagctata aggttattgt cctgggtttc aagcattagt ccatgcaagt
    24001 ttttatgctt tgcccattct atagatatat tgataagcgc gctgcctatg ccttgccccc
    24061 tgaaatcctt acatacggcg atatcttcta tataagcgta ccggttccaa ttttttcgca
    24121 gtttaacttt tccgacgcat ttatcgtctt ggtagtaaag atatattatc ttatcagtat
    24181 tgtcaatata ttcaaggcaa tctgcctcct catcctcttc atcctcttcg tcttggtagc
    24241 tttttaaata tggcgcttca tagagtaatt ctgtaaaggt ccaattctcg ttttcatacc
    24301 tcggtataat cttacctatc acctcaaatg gttcgctggg tttatcgata tctttcaggt
    24361 gccctgcttt catttctgta atcactgttc ccgcctctct tctatatcag cggcatatgt
    24421 gctatccagg cagccggttt taccagtgta ttttttatac atgtccctgg tatattttgt
    24481 tatattccta tcatactccg gataggcata atgaagcctt tccgccacct caccggatac
    24541 cgccctgaac aattgatggc atagaaataa tgcttcccat atgttttcat aggaatccat
    24601 ccggtaggtg gacaaaagtt tctcccacaa atcctcggat atataccttt caataaactt
    24661 atagttcttg cctacactta atttaaagcc tgtttcgatg ccgaccttcc atgatatcat
    24721 tctcagcagc tcatggcgaa caatctgatt aaaatgatca atagcaaata aaatttcctt
    24781 acggcacaat cctttaataa cataaggtgt tacattccaa aattcattgc agcaatcatc
    24841 atactccctt gcgcttggct ttcttacatg ataatctata tcagtcggaa ctatgtccct
    24901 tttaattcta caatctttat caattagaac ctttattaat ttatcgccct ttaggtaatt
    24961 atctaactct tccaagggca ataaggtaag atcaatttta ttgtaatcat caaatagcat
    25021 aagataggaa aatccctttt cttcaggtgg gaataattcc atatcctccg gcttttgcat
    25081 cattattata ttcccaaatt gattaagcca gtcatcatta gatataaacg gttctatatc
    25141 acttacaaaa tatgtaatat cataatcctg aaattcatct ttaggtatat taatatttgc
    25201 gcgtgacccc tcaagggtca caattcgaat acgttcatcc tgttctgcta aagaaagtac
    25261 taaatccatc atttcttttt ctgatctcat ttacatactc ctcgtttatt ttttctatat
    25321 tattacatct tcttttttgc cgatacaatc agcatcattg ggcgtcgcat ttcatccgcc
    25381 atccccggaa tatccatcat gttctctggc ggctgtggct ccacaatctg atttattata
    25441 aaactatttg aaagcagtgt atttagatat gtggtcagtg ttctatgata ttttgtaacc
    25501 ttttcttcca aaaacatagc tgtccgtttg ccctcataat aataattgtc caccgggaaa
    25561 tgcagtattt ctcctttttc gttataatac cagtcttgtg ttccatgagc agtaaaaaca
    25621 ggatgttcaa ctgtaaaaac taaattgcca ccagccttca gcatcctata tatctttttt
    25681 attaaattct catagtctgc tacataatga aacgcaagcg aacttagtat tacatcaaag
    25741 ctctcctctg ggaaatccac atcttctatg gcacagcatt catattcaat ctgtggaaaa
    25801 tgggtttttc cttttgctac ttcgagcatt ttatgagaaa tatcaacacc tactacagag
    25861 gaagcaccgt tttccatcgc atatatacag tgccatccat agccgcatcc taaatcaagc
    25921 acacgcttac ccttaaaatc aggtagcatc tttttcaaag tctcccattc tcccgcacca
    25981 gccagtcctt tctgcgagcg actcatttga ctgtattttt gaaaaaatat attatcatca
    26041 tatttgtttt ctttcatctg aactctcctc gtttaaaaag ttatttatct ccgatacaat
    26101 ttcattcact tctttataaa gtttctcggt catgtcgtag cattcaaaaa gagaaagacc
    26161 gagtacttca aaaatatgat taactctttc ggcatatttt tcaggtttat attcaaaagt
    26221 ttcaagcagt tttatagctt tcttttcgtt aatgcaataa gcattattac atgcaaatag
    26281 tacttgattt aagcatgaaa taatacgaaa aacatggcct gcaatataat atttatcctc
    26341 tgcccccgca tttgctttta caaacattaa agagaattca gcttcaaata taaaaaagtt
    26401 catcaagctt ttctttagag cagtagggta aatttctgcc tgctttttta attcgcataa
    26461 gctttcgttc ttagcatata gtattttact aatcgctaat tctccacgat acatagcact
    26521 tatataacca tggggatgcc cggtctgata attggcagta acaattcctt gctccgtatc
    26581 tttgattatt tgttccaccc gttttatatc acgtaatatc aagtcaacat gacacccgtt
    26641 tataactaac catccaccgc cattaaccca atcaccccac gctccgggag gtacaacaag
    26701 gttgtttcta ttctcatcat ccaactctgt agcaatttga ttaatcgctg tcaggtcaaa
    26761 tgagtctgaa ttgtaataga ttccgatatc tatatcagaa ttttctgtat gggtgcctct
    26821 tgcacgtgag ccccctaata cgatgccttc tataaaaggc aaagatgata atttctctgt
    26881 tactatttga ataacattac ctaccatata aacatcctcc tttattcgtt agatattttt
    26941 atttcttctc catctggtaa aataaatgcc tgcacaaact tgacacctag cacatcagca
    27001 atggccttca actcatccaa ggttactgtt tctcgttgta attttttatt gaaattctgt
    27061 ggagtctggc caatacgtct agcaagttcg gaaacactta tattcatttg ctcacacagt
    27121 tctttaatca tttctgccgt agtcatacag cacctccaag tttacgctaa gaatattata
    27181 aaccatttgg ttgataaaca caatagttat taaaatatta ttataatcag caagcaaaag
    27241 aaaacccaca actctactgt agagtcatgg gctatttact tctggttttc atatttccat
    27301 ttcgatgcca gatttgaagg ctatgacgaa gtggccttca tagactgtaa cgctctggat
    27361 tatcttcctt acaagcttat catcatattc taaggtgcgg aatttgttct tgcggataaa
    27421 ttcaatcagc tcattgattc gctcgttctc gccactgagg gaggcatctt ctactaaaag
    27481 gatctgtcgc ttgtctctca gctcatcaat ctcatctgct aagtggtcat agtcttgacc
    27541 cttgttcgcc agcttgatta gttctttttg tttttcctct agtgagttgt taatctctga
    27601 aatttggtat tctgtggttt cgccaatcac agcatgaata ttctcttcca gtgtctttat
    27661 catattgttc ccacctgcaa gtagcttatt aatcgcagtc attactgcac cataaagttc
    27721 atcttctttt acggttcggt tcttacaaac ttcaggacct tgctcgattc tagtcacgca
    27781 tcgccagaca aattcttttc ttccgtggat attccaatag acccgtctat aaatatcgcc
    27841 acaatctcca cagaaggtga tggcacttaa agcgtacttg ctactgtaaa ttcttttgtt
    27901 cttgccttct cctgtgtaga tattgcttct ccgatgaatt tcttcttgcg cctgcaaaaa
    27961 taactcttta ggaataatcg cttcatggct attttcaaca taatattggg gaacatgccc
    28021 ttcatttttc actcgtttct tggtcagaaa atctactgtg acagtctttt gcagaagggc
    28081 atctccgatg tatttttcgt tttgaagtat cttcttaact gattctggtc gccatcttgg
    28141 ttttcccgct gctgttaaaa taccatcctt ttcaagggct cgaccaatgc ccactagact
    28201 ctgaccctca aggtattctc ggtagatgcg tttgataatc tcagcttctt cggggacaat
    28261 agttaaattt ccatcttcat ctttcgtgta gcccataaat cgcttatggt tgacctgcac
    28321 ctttccttgt tggtatcggt actgtagccc aagcttaacg ttttgtgaaa ggctctggct
    28381 ttcctgctgt gccaaagatg ccataatagt cagcaaaacc tcacctttgg catccgtggt
    28441 gttgatgttc tctttctcaa aataaactga tatgttctta tccttgagct gtctaatgta
    28501 ttgaaggcag tctagggtgt tacgcgcaaa tcggctgatg gattttgtaa taaccat
//
