LOCUS       NZ_LR134113             7165 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Enterococcus faecium isolate E6043 plasmid 0.
ACCESSION   NZ_LR134113
VERSION     NZ_LR134113.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA4884790
            Assembly: GCF_900635415.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7165)
  AUTHORS   Arredondo-Alonso,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-DEC-2018) UNIVERSITY MEDICAL CENTER UTRECHT,
            Heidelberglaan 100, 3584 CX Utrecht, Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 02:29:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 65 of 139
            Pseudo Genes (incomplete)         :: 75 of 139
            Pseudo Genes (internal stop)      :: 34 of 139
            Pseudo Genes (multiple problems)  :: 28 of 139
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR134113.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..7165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /isolate="E6043"
                     /db_xref="taxon:1352"
                     /plasmid="0"
     gene            <1..609
                     /locus_tag="ELZ65_RS16205"
     CDS             <1..609
                     /locus_tag="ELZ65_RS16205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_126341293.1"
                     /translation="HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERG
                     KKPEKRTMSEIKLKEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRG
                     KNFTYELIHKKKKVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAE
                     EVRREQRTLTPEQPEIRPARRNHEQHVERGTDHQQELSL"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            569..847
                     /locus_tag="ELZ65_RS16915"
     CDS             569..847
                     /locus_tag="ELZ65_RS16915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002348700.1"
                     /translation="MKEEQTTNKNYRSKTLKDIENEIKKQRAFLVPYTQERIQTTIDLQ
                     VKKLHQELLDQRNKEQKKVLIQRSLDFLAPLCCLVLTLFAFWLVWGG"
                     /name="hypothetical protein"
     gene            849..1538
                     /locus_tag="ELZ65_RS16215"
     CDS             849..1538
                     /locus_tag="ELZ65_RS16215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_031592678.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFLG
                     CIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTTCY
                     KEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKIEEA
                     CSDLFGDTNPWFASEEEKKEKQQSVTYERYENLFQQATNMQNPTKKETALNYLKSVKEW
                     LDQQQQN"
                     /name="hypothetical protein"
     gene            complement(1659..1745)
                     /locus_tag="ELZ65_RS16220"
     CDS             complement(1659..1745)
                     /locus_tag="ELZ65_RS16220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018113589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_109746925.1"
                     /translation="MFEQFICPLLVGVCVSLFSYWLNNRNKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            2390..3127
                     /locus_tag="ELZ65_RS16225"
     CDS             2390..3127
                     /locus_tag="ELZ65_RS16225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_002305239.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEIF
                     TFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDKVN
                     ETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKGHWF
                     VKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAYKGNK
                     IGSLQIYFEENIPSITLDNWLEK"
                     /name="replication initiation protein"
     gene            3156..3677
                     /locus_tag="ELZ65_RS16230"
     CDS             3156..3677
                     /locus_tag="ELZ65_RS16230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_031592680.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKVV
                     LRSGVLQLASNLGNQRLLDRLHEYEQENDKNVYISRKNVVVNELLDKLREENEFLREQL
                     SLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEEPEEEVLTSVNKENNNAI
                     TTEKKWWKFW"
                     /name="DUF536 domain-containing protein"
     gene            3761..4213
                     /locus_tag="ELZ65_RS16235"
     CDS             3761..4213
                     /locus_tag="ELZ65_RS16235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339186.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_025089292.1"
                     /translation="MTISKVIKQKRIEKQLTQEDLAEMLLVSKKTISNWENGRTIPDTE
                     NLIQFAKLFDLSLDNILLGEEKVMLKNHTKTLILLFHFVIFLSLVFTLIQSKFFYFSHS
                     IATWLLIFFLSLLLVINTLIIIFNKHKNLFLHSVFPIILLSFLYFV"
                     /name="helix-turn-helix transcriptional regulator"
     gene            4624..5778
                     /locus_tag="ELZ65_RS16240"
     CDS             4624..5778
                     /locus_tag="ELZ65_RS16240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /GO_function="GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="WP_044383358.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQPI
                     EEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFSDA
                     DNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNGQIK
                     LLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDNFIMI
                     NWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKSLNQDQ
                     IIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALALFGWVNQ
                     GGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
                     /name="C47 family peptidase"
     gene            5751..6194
                     /locus_tag="ELZ65_RS16245"
     CDS             5751..6194
                     /locus_tag="ELZ65_RS16245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002318191.1"
                     /translation="MGQYHYKLVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGT
                     WQTKDHSERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLT
                     LRSNKKQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
                     /name="hypothetical protein"
     gene            6498..6878
                     /locus_tag="ELZ65_RS16250"
     CDS             6498..6878
                     /locus_tag="ELZ65_RS16250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_047936909.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEALQ
                     MSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPGDA
                     QRLSENLKIMQKELQKIWQQLK"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            6860..>7165
                     /locus_tag="ELZ65_RS16255"
     CDS             6860..>7165
                     /locus_tag="ELZ65_RS16255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_172595663.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIRM
                     LYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     Typing          2391..3127
                     /name="rep_cluster_1742"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6861..7165
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="8.63e-61"
ORIGIN
        1 cacattgtca ttaactccgt taatctggag actggaaaaa aatttcaagc tcatggtcaa
       61 gcatttctaa acaaatgtta tgacctaaat gacgagattt gtcttgcaca taacttacca
      121 atcactgagc gaggaaagaa accagaaaaa cgaaccatgt ctgaaataaa attaaaagaa
      181 aaaaatgaac ctgtttggaa agacgaaatt cggattgcga tcgatcaaac aatgaaaaac
      241 aaaaaaacca gaacctatga ccaattttgt aattccctca aaacattggg gattcattgc
      301 ttcaatcgcg ggaaaaattt cacttacgaa ttgatccaca aaaagaaaaa agtacgatcc
      361 aacagactag gaaaggacta cgaaaaggag acgattttac atgagctgga cagacgagaa
      421 cgaacctata accaacagcg aaccaacgag ctacgaagag ctcgagctag cattcgcgaa
      481 actgcagaag aagtacgaag agaacaacga actcttacgc ctgaacaacc ggaaattaga
      541 ccggctcgaa gaaaccatga acaacacgtt gaaagaggaa cagaccacca acaagaatta
      601 tcgctctaaa acgttaaaag acatagaaaa cgaaataaag aaacaacgtg cttttctcgt
      661 tccttatacg caagaaagga tacaaactac gattgattta caagttaaaa aactccatca
      721 agagctatta gaccagcgaa ataaggaaca gaaaaaggtg cttattcaac gatcattgga
      781 ttttcttgcc cccttatgtt gcttagtcct gacactgttc gcattttggt tagtatgggg
      841 aggctaaaat ggcattttat ttaccctatc tactcatttt tgttagtatt tcaggaagta
      901 tttggctcat ctataaaatt tttcaaacaa gatattcatt aaaaggctct aaaattcgat
      961 ttaagcgatt tttctttctt ggctgtatat tttccttgat aatcgtttca agcggcttat
     1021 tcggcgtttt agagggaaat aagcgcgttt ctagaagtat tttattagga aatgtcactc
     1081 aaaagtatga atcagcgcgt gataaaaaga aaaaagagca agcattagca caaaaaatgg
     1141 aagagtttac cacttgttat aaggaaatga acgatatttt tgtgaatcaa gaaaaacgtt
     1201 tgacggataa aaacatggaa aaactcactc gtctttatca aaacttgcca gaaaaacagc
     1261 aaaaagaggt tcaagacaac tatgagcgaa ccaaaaaaga cgtgcaatat gtaaaagata
     1321 caaagataga agaagcctgt agtgatctat ttggagacac aaacccttgg tttgccagtg
     1381 aagaagaaaa aaaagaaaaa caacaatctg tcacatatga acgctacgaa aacctgtttc
     1441 aacaagcaac taacatgcaa aatccgacaa aaaaagaaac cgccttaaac tatctaaaaa
     1501 gtgtcaagga atggttagat cagcaacagc aaaattgaat ttgattgaaa ctcatgttaa
     1561 actgaatgtg caaatgatca aacattagat acacgaaagc cccagagagg tcggattctc
     1621 tggggctttt tttcaggttg atgtcgcctt tactgatttt acttcttgtt tcggttattc
     1681 aaccaataac tgaataaaga gacacaaact cctacaagaa gggggcaaat gaactgttca
     1741 aacattagat acacctcctt ccagtcgcaa gactgtcgga taggcgacaa gttattatac
     1801 cctacaaaat taaatctgtg tggcgatttt aagtatacct tattttcggg ttgttagggc
     1861 ttgccctgac cgcctgtaag gcgcttctcg actagattaa gggagttaat caagaattgt
     1921 cttagaacgg cttagacaag ctctcagatt ctcccacctc ctctttgaac aacggtttta
     1981 gcaaaggagc cggaggcgac tgcgcaggta caatgtgaga gcgtagcgat cacacctttt
     2041 tagcgaccgt agggagcaag ttttctagtt tagaaaaatt cgcgaacctt tttggaggta
     2101 aaagtaggag ttttttaggc gggaaattaa atgtgctctt aagatatact gttagatata
     2161 ctgttagata tactgttaat aataactgtt agggattagc aaccttatgg gagagtaagt
     2221 attgacatag gtagtggggg ataaattgtc acactatggg ggataaattg tcacactatg
     2281 ggggataaat tgtcacacta tgggggataa attgtcacgc tatgggggat aaattgtatt
     2341 ttacaccctc ttatgtctat gataacataa tttattgagg tgatttttat tgagtaacga
     2401 tatagttcga tataataatg gattaaattc tgtcccttta agaaaattta cccctataga
     2461 tatggattta ttttggggaa tatgttctaa aatgaaaaga aaaggtacaa aagaagaaat
     2521 ttttacattt aaacaaataa aagaattaat tgattacaat ataaatgcac gtggcgaccg
     2581 ttttgctaat gatttaataa aaatgtcaaa aaaaatcatt actttgtctt ttatttatga
     2641 agacgaaaaa acatatgaac aattaaatct gtttcaaaaa tttaaaatcg ataaagtgaa
     2701 tgaaacatta ttaataaagg tttctgaaga atttgaatat atacttaatt caatcggaac
     2761 taattttact cgtttcgaat tagaaaatat gacaaactta aagagtagct acgttaaaga
     2821 gttatatcgc caacttatgg ctcataaaga cagaagatct aaaaaaggtc actggtttgt
     2881 aaaaatagaa gattttagag ctctattagc aataccagaa agttatcgca tgagagatat
     2941 tgataaacaa atttttgccc aagcgaaaaa agaattttta aacgttaatt caactcaccc
     3001 tgctattttt aaaacttttg aaatcaaaaa aattaaagcc tacaaaggaa ataagatagg
     3061 atctctgcaa atttattttg aagaaaatat accttcaatt accttagata attggttaga
     3121 gaaataataa cctaacaatt taggaggcaa ttatcatgca acccaaagaa acctttacaa
     3181 taaaggaatt atctgaatta tttgaaataa gtaggcaagc aatttctaaa catgttgata
     3241 aattagaccc gtccttatta gctaaaaatg agcgtggtta taaggttgta ttacgttctg
     3301 gagtattgca acttgctagc aacttaggta accaaaggtt actagatagg ttgcatgagt
     3361 atgaacaaga aaacgataaa aacgtttata tatcaagaaa aaacgtggtt gtaaacgagt
     3421 tgctagataa gttgcgtgaa gaaaatgaat ttttacgaga acaactttct ctcaaagagc
     3481 aaaataattc taatatgcaa aaattactcg accagcaaca acaactcacc ttgcaggcaa
     3541 atcaacagat cgaaaaactg caagaacagt tacaattagc ttatacggaa gaacctgaag
     3601 aagaggtatt aacttctgtc aataaagaaa acaacaatgc aataacaaca gaaaaaaagt
     3661 ggtggaaatt ttggtaacaa ttaccaactt tccataaaga agaaatcaat ttctatagac
     3721 tttatctttc taaaaataaa aaatatgttt aggtgatcaa atgactataa gtaaagtaat
     3781 caaacaaaaa agaatagaaa aacaactaac tcaagaagat ttagctgaaa tgcttttagt
     3841 atctaaaaaa accatttcta attgggaaaa tggtagaaca ataccagata cagaaaattt
     3901 aattcaattt gctaagttat ttgatttatc actagacaat attttgttag gagaagaaaa
     3961 agttatgtta aaaaatcata caaaaacact aatactatta tttcattttg taattttttt
     4021 aagtttagtt tttaccttaa ttcagtccaa attcttttat tttagccatt caattgccac
     4081 ttggttatta atattttttc taagtttgct attagtaatc aatactctga ttattatttt
     4141 taataaacat aaaaatttat ttcttcatag tgtttttcca attattttgc tgagtttttt
     4201 atactttgta taaagtataa aaaaagactg ctctttcgag cagccagtta aaaaaataat
     4261 gagagtttat tcttgaaaaa gcaacgcgct tataaagcgc taccaaaatt ttatcatatt
     4321 ttataaaaaa taacaatcca gtaaaaaatg actggtaaaa attcacaaag aaacggaaag
     4381 aagcaactgc agaaaatcaa gccttaaaaa aagcttttga cctagaccaa tgaaaaatca
     4441 caaagtgagc agctatagcc cttgatagag gggctacttg gcatagtcga cattatgtta
     4501 actaacgcta taaataacga ttatgttccc aaaacaatat tttatgaact ataacaaaaa
     4561 tttgttatcg catattgtat attttaatta taggtgtata ccacttaaat ttaacacaaa
     4621 ggcgtgatta ttttgaaacc caaaaagaaa atttatctag gtctcctctt ttccttgatg
     4681 attggaattt ttagtatagg aattacaaat acctatgctt cagaaaattc taatttcaat
     4741 atcaactccc aaccaattga agaacaagca attaattttg cgaaaactga ttttgaacac
     4801 tccataactt caattctttt aatggaaaat aacaccgaaa ctgatattaa ctatactctt
     4861 ggttcgccat ttaaaatgct cgatggagaa aatacggcaa atagttctat tttctttcca
     4921 gtattttcag acgctgataa tacgattaaa tatatttata ccgtcaaaaa aaatacaaat
     4981 ggagaatatt caggaagtat ttcacaattt ttagcaaaag aacttcaaaa tctagtagat
     5041 agtaatataa cagatacaac cttatttttt caagataata gcatttatta ttccgataat
     5101 ggacaaatta aactactttg gaaatcacct ttaagtacag aaaaaaatgg tgtttcttcc
     5161 tttacagaaa aaaatgatct tatatccgta aatataaaaa ataaaattaa aaatttctct
     5221 aaaaaacaaa attttcctgc ggttaaacgt gtaaaaagtg tctcctccgg agataacttt
     5281 attatgatta attggcgtat agcagaaacc caaacaagtt ttccgtggtg tgctgcttac
     5341 gtagaagctg ctatcttatg taacaaaaca gatgtacgtg ctacttcagc tagagccatt
     5401 atgcattata cctatcctaa tttaaacaac agtcaaattg aatcaaaaag tcttaatcaa
     5461 gatcaaataa taaaatatgc aaattactgt ggtgtttatc ctaaaaaagt agcacgaata
     5521 ctaaaccttt cagaggtcca aacacaacta agaaaaggaa atgccattta tatgggaact
     5581 gctggttatg gaaattatag taacagccgt catgcacttg cattatttgg gtgggtcaat
     5641 caaggtggtt atcaaactta ctatgtgtgg aatccttggt ataactaccc aactgtaata
     5701 agtgcaaatg caggaccagt tacaattcct gtacctggag gtggttttac ttgggacaat
     5761 accattacaa attggtaaat aaacccattg ctttagttat gggtctagtg ttagttcttt
     5821 tcttaactag ttgttcaaaa aaacaagaaa tacaaaagac tgatctgatt ccttttctag
     5881 gaacttggca aactaaagat cattcagaac gtctagtaat cactaattta aatacttcaa
     5941 aaaatataga acaatatacc atcttagtaa aagagaacaa tcataaaatt caaatcattg
     6001 ataaaaattt aaatataaat gaacaagttt tcatttacaa agcaacaaat aatttactaa
     6061 cactgcgctc taataaaaaa caattagatt acacttttag tttggattct ccaaaaaagc
     6121 tcgtatttat tttgacaacg aatgatggga cagaagggac agctaaacca attgaatttt
     6181 ttaaagctga ttgatgaata gttgtttgat attacaaaac aataatttca ccgaaggtga
     6241 aacaagcgaa actttacaaa aagtggctag catttgctag ccttttttgt attgtggagc
     6301 gtgggttttg agggggattc aagggggagc ttgcgcccct ttgaaaagcg gttatttgct
     6361 agccaaatac gtaggtattt ggctagcaaa tatagagctt gccaaaccct tttagtgagc
     6421 tttactcatt gtaccttttt aggtacaatg gtattgcgaa cgatacgtcc gtaggacgta
     6481 ctgaaagggt gggacttatg agcgaacaaa atcaaaattt ggctagcgat cattctaaaa
     6541 aatataccta tcgatccgag ccaaaacaaa tcagttttcg agtgagcgaa tctgaatttg
     6601 caaagctgaa gcagtcagct gaagctttgc aaatgagtgt gccggctttc gtgaaagcca
     6661 aggcacaaaa cgcgcgtctg gtgacaccga aagtggcgcc agacattgcc caggcaatcg
     6721 cgcgcgattt agccaaagct ggagggaata tcaatcaaat tgctaagtgg tgtaatacac
     6781 accaacacga cgttgctcct ggagacgccc aacgcttatc cgaaaaccta aaaatcatgc
     6841 aaaaggagct acaaaagata tggcaacagt taaagtaagc cgaaccactt cttgtagtcg
     6901 tgcaattaat tacgctgaac cacgagcaac cattaaaaca ggaataaact gtgacgtcga
     6961 ttatgccaaa agtgaaatga aacaaattcg catgctgtat ggaaaagacg accgtgtaca
     7021 ggcacactta ttgattcaat cttttcgacc aggagaaatt accgctgaaa aagctaatca
     7081 actaggggca gagtatgcaa aaaaaatagc ccccgatcac caaatagcta tttacacaca
     7141 tacagacaaa gaccatattc ataat
//
