LOCUS       NZ_LR130519            27037 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Staphylococcus aureus strain BPH2986 isolate BPH2986 plasmid 2.
ACCESSION   NZ_LR130519
VERSION     NZ_LR130519.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA5099554
            Assembly: GCF_900620255.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1
  AUTHORS   Seemann,T. and Baines L,S.
  CONSRTM   Bioplatforms Australia Antibiotic Resistant Sepsis Pathogens
            Initiative
  TITLE     Direct Submission
  JOURNAL   Submitted (21-NOV-2018) Bioplatforms Australia, Level 4, Bldg F7B,
            Research Park Drive, Macquarie University, NSW, 2109, Australia,
            Australia
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 03:03:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,968
            CDSs (total)                      :: 2,886
            Genes (coding)                    :: 2,800
            CDSs (with protein)               :: 2,800
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 45 of 86
            Pseudo Genes (incomplete)         :: 41 of 86
            Pseudo Genes (internal stop)      :: 18 of 86
            Pseudo Genes (multiple problems)  :: 17 of 86
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR130519.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27037
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BPH2986"
                     /isolate="BPH2986"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="2"
                     /geo_loc_name="Australia"
                     /collection_date="2008-12-05"
     gene            complement(318..1010)
                     /locus_tag="EW031_RS15315"
     CDS             complement(318..1010)
                     /locus_tag="EW031_RS15315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            1120..1314
                     /locus_tag="EW031_RS15320"
     CDS             1120..1314
                     /locus_tag="EW031_RS15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            2430..3047
                     /gene="cadD"
                     /locus_tag="EW031_RS15325"
     ARG             2431..3044
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3066..3413
                     /locus_tag="EW031_RS15330"
     CDS             3066..3413
                     /locus_tag="EW031_RS15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3570..3662
                     /locus_tag="EW031_RS15335"
     CDS             3570..3662
                     /locus_tag="EW031_RS15335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(3834..4805)
                     /locus_tag="EW031_RS15340"
     CDS             complement(3834..4805)
                     /locus_tag="EW031_RS15340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            4929..5348
                     /locus_tag="EW031_RS15345"
     CDS             4929..5348
                     /locus_tag="EW031_RS15345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(5874..6719)
                     /gene="blaZ"
                     /locus_tag="EW031_RS15355"
     ARG             complement(5878..6719)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6826..8583
                     /gene="blaR1"
                     /locus_tag="EW031_RS15360"
     ARG             6827..8580
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            8573..8953
                     /gene="blaI"
                     /locus_tag="EW031_RS15365"
     ARG             8574..8950
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            9217..9795
                     /locus_tag="EW031_RS15370"
     CDS             9217..9795
                     /locus_tag="EW031_RS15370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(10018..10203)
                     /locus_tag="EW031_RS15375"
     CDS             complement(10018..10203)
                     /locus_tag="EW031_RS15375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            10465..11139
                     /locus_tag="EW031_RS15380"
     CDS             10465..11139
                     /locus_tag="EW031_RS15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(11308..11879)
                     /locus_tag="EW031_RS15390"
                     /pseudo=""
     CDS             complement(11308..11879)
                     /locus_tag="EW031_RS15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(12155..12949)
                     /gene="aph(3')-IIIa"
                     /locus_tag="EW031_RS15400"
     ARG             complement(12159..12949)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13042..13572)
                     /gene="sat4"
                     /locus_tag="EW031_RS15405"
     ARG             complement(13046..13572)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(13569..>14204)
                     /locus_tag="EW031_RS15410"
                     /pseudo=""
     CDS             complement(13569..>14204)
                     /locus_tag="EW031_RS15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(14345..15019)
                     /locus_tag="EW031_RS15415"
     CDS             complement(14345..15019)
                     /locus_tag="EW031_RS15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<15076..15252)
                     /locus_tag="EW031_RS15420"
                     /pseudo=""
     CDS             complement(<15076..15252)
                     /locus_tag="EW031_RS15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(15266..16003)
                     /locus_tag="EW031_RS15425"
     CDS             complement(15266..16003)
                     /locus_tag="EW031_RS15425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(15996..16925)
                     /locus_tag="EW031_RS15430"
     CDS             complement(15996..16925)
                     /locus_tag="EW031_RS15430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(17041..17922)
                     /locus_tag="EW031_RS15435"
                     /pseudo=""
     CDS             complement(17041..17922)
                     /locus_tag="EW031_RS15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(17919..>18296)
                     /locus_tag="EW031_RS15440"
                     /pseudo=""
     CDS             complement(17919..>18296)
                     /locus_tag="EW031_RS15440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(18354..19028)
                     /locus_tag="EW031_RS15445"
     CDS             complement(18354..19028)
                     /locus_tag="EW031_RS15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            19502..20968
                     /gene="msr(A)"
                     /locus_tag="EW031_RS15450"
     ARG             19503..20965
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            21067..21966
                     /locus_tag="EW031_RS15455"
     CDS             21067..21966
                     /locus_tag="EW031_RS15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            22452..23060
                     /locus_tag="EW031_RS15460"
     CDS             22452..23060
                     /locus_tag="EW031_RS15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            23306..23644
                     /locus_tag="EW031_RS15465"
     CDS             23306..23644
                     /locus_tag="EW031_RS15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            23649..23834
                     /locus_tag="EW031_RS15470"
     CDS             23649..23834
                     /locus_tag="EW031_RS15470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(24061..24804)
                     /locus_tag="EW031_RS15475"
     CDS             complement(24061..24804)
                     /locus_tag="EW031_RS15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            25199..26182
                     /locus_tag="EW031_RS15480"
     CDS             25199..26182
                     /locus_tag="EW031_RS15480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <26202..26491
                     /locus_tag="EW031_RS15485"
                     /pseudo=""
     CDS             <26202..26491
                     /locus_tag="EW031_RS15485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(26690..>27037)
                     /locus_tag="EW031_RS15725"
     CDS             complement(26690..>27037)
                     /locus_tag="EW031_RS15725"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223289333.1"
                     /translation="DISPFIKIAILITILNTFILDFKRHFEDLEANHIGFVLKNLYSLL
                     KRKYEPNKYMLISQTKISAKSVTNFLDTAHLHANLKISIKYFKTSPCFSKFLQGFSYQK
                     LRNFNLTLKSP"
                     /name="hypothetical protein"
     ARG             21068..21963
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19503..20968
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             21068..21966
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(13043..13560)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(13867..14168)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(5875..6719)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          26548..26695
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(24062..24804)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          25200..26182
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          26314..26483
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 atgaagatta aaactttcgc tacttttact catcgtcaat tagataaaca agttaatagg
       61 tttttaaaga atgatattca tgtattagaa attcaaacac acagtaattg gttatatatt
      121 tcagctattg ttttttatga ggataaataa ggaacatcgt atttatgccg aaaaaattta
      181 ttgatgttga gaagaaccct taactaaact tgcagacgaa tgtcggcata gcgtgagcta
      241 ttaagccgac cattcgacaa gttttgggat tgttaagggt tccgaggctc aacgtcaata
      301 aaacaattgg aataaaatca acctacagag catccagctg caaatgcagt tccgcaaact
      361 gcttcacata caccgccggc tattggattt acgattgccc atactccaca gtagtgagca
      421 catgcataaa gtccagccat actacaagcg aatgctttgc cgttccattt gaatcctgca
      481 tatgttaccg gtctgttttt atcaactttt tcagccttat attcaacgta atttttgtta
      541 ataagtattt ttccctcttt gttttcagtc atacttcttt tttcggcaat gaattttgtg
      601 atttttttgt tgtagttatc atatattgtt tcagaaacta caatttcttt tgttttttca
      661 tttttataag cgttattagc tatgtagcca tatgcatttt tatcatttgc ttctgtagct
      721 agatatttta atttagaatt tttgtcttct agctttattt ttttaaatcc ttcttttttc
      781 atttgctttt cgaatttttg catatcttca tttttatttt gcaattgttc tagaaaactt
      841 atttctttct tggtcatttg tgatacttcg atgtttttgc ttttcaattt ttctttttga
      901 ttttctagta aagaactttt ttgttcttca tttgcgtaag cattagaaaa attcgcgcta
      961 aataccagta ggaacaagga aattattgaa aataatttta taattttcat ttgatacctc
     1021 caagataata agatatttta attgtataag taagcgcttt ataaaatcaa tatttatttt
     1081 aatatattta taaacatatt tttgaaagga gtctatttta tgaatgaaaa tttagaaaaa
     1141 tatataaaaa gtttgccact tttaggtttg ttaattagta ttttgttaat tgttttattc
     1201 ttttttattt tagatgttga tgaagattta ttcgtggttt ttttatactg tttattgcct
     1261 ttgatagtta atttgtctat ttatggtttt tatgtttttg ttaaaagaaa gtaagattat
     1321 gaataatttt gtttttaatt tgtatgcttt gagggggttg gaaaacggta ggtgtataga
     1381 ttagatttct tgtttttttg aaacgagtgt gaacgagttt cttcttgtct tgatttttga
     1441 taaaaacgcc ctacaggaat ttagaaaaac gtggggaagt tttaaagaat tttatgctaa
     1501 tttttaattt gcatgtaaat gggcagtgtc taaaaatagt tattgttttt gctcaaattt
     1561 ttgtttttga aaatagcata tatttatttg gctcatattt gcgttttaaa agcatatata
     1621 agttttagat ataaaactat atgaatcacc cctaaatctt taaaatgccc tcttaaaatt
     1681 caaaataagg gcataaaaaa taaaagctac cccagataaa gtgaggtagc tttttctttc
     1741 atacggtcta tttatttttc tttcgacgcc gtatcgtcga tgtaattcaa aaaagttatg
     1801 ggctataaat ctacatcact ttttcaagaa tgtagtagca atattcaacg caaattaatt
     1861 tttataactg ctcggaatat ctcaagccgt ttctttaatt ttgaaataaa aaaatcgacg
     1921 aaggtcgatt acgtttttgc acatgtcgat ttatccgacg tataagtgcg cccttacggg
     1981 atttaactag attataacga cgaattttag acctgtaaag caataacaat taggtctacc
     2041 aggtagataa agtgtacaaa gtagaaccga aaaagttatt tattttgaag atttttcgta
     2101 gatataattt gctaataaac ttcctaaaac tgaataaaga aaaatagtta aactcatgta
     2161 atcactccat aattctgaag tgtctccatg tctacgcata gacacgcatt tatgccgaaa
     2221 aaatttattg atgttgagaa gaacccttaa ctaaacttgc agacgaatgt cggcatagcg
     2281 tgagctatta agccgaccat tcgacaagtt ttgggattgt taagggttcc gaggctcaac
     2341 gtcaataaag caattggaat aaagcaccta tgattattta aaaatataag ttataataca
     2401 ttcaaaaata tttttgaatg aggtgtatta tgattcaaac ggttgttgct gctgctgttc
     2461 tttatattgc tacagcagtt gatttattag taattttatt aatatttttt gctagagcaa
     2521 agactagaaa agaatataga gatatttatg ttggtcaata tttagggtct attattttaa
     2581 tattagttag tttgttttta gcttttgtat taaattatgt tccagaaaag tggatattag
     2641 gtttattggg tttaatacca atttatcttg gaattaaagt ggctatttat gatgattgtg
     2701 aaggagaaaa gagagctaaa aaagaattga atgaaaaagg attgtctaaa ttagttggta
     2761 cggttgcaat tgttacgata gcaagttgtg gcgccgataa tattggttta tttgttccgt
     2821 attttgtgac attaagtgtt actaatttat tacttactct gtttgtcttt ttaattttaa
     2881 ttttcttctt ggtgtttact gcacaaaaat tagctaatat tccaggaatt ggagaaattg
     2941 ttgagaaatt tagtcgttgg attatggcta ttatttatat agctttaggt ttatttatta
     3001 ttattgaaaa tgacactatt caaacaattt taggatttat attttaattt agggtgtgat
     3061 tttatatgag ttatgaaaat acttgtgatg tgatctgtgt acatgaggat aaagttaaca
     3121 atgctttaag ttttttagaa gatgataaat ctaagaaatt acttaacatt ttagaaaaaa
     3181 tttgtgatga gaagaaattg aaaatcatat tatctttgat taaagaagat gagttgtgtg
     3241 tttgtgatat ttctttgata ttgaaaatga gtgttgcttc aacttcacat catttaaggc
     3301 ttttatataa aaatgaggta cttgattttt ataaagatgg aaagatggca tattatttta
     3361 ttaaagacga tgaaataaga gagtttttct ctaaaaatca tgagggtttt tgaaacgagt
     3421 ttcttcttgt cttgatacta taaaaaacaa agttatataa cataagacga cttatcggaa
     3481 gtagatatgc ttgtatattc acagatggta taataataga gtcgcctatc tctcaggcgt
     3541 caattgacga agagaggagg tgcattactt tgctaatcat tttcgttcac atcatagcac
     3601 cagtcatcag tggctgtgct gttgcgtatt atacttattg gcttagtaaa cgcaacaaat
     3661 aattaatagg cgactttata agccagcatc gaaaaaatcc ccacactact gcaatagtgt
     3721 ggggattggt gcattaattg ttaatcattt tcgttatata aattataaca ctggttagta
     3781 gagaaatgca aaatgattga attaatagta aatgtattaa tgaatactca cacttatact
     3841 tttaaaatag ttcttcctaa atgttgtcct tttaaaagct gatctatcgt tttatagaat
     3901 tcttcaaatc caatttcatt gtatagaagt gaatttccta tattccattc atttgctaac
     3961 ttactccata tatcttcacg gatattatga tcaacatata cagaatcaat gccaattaat
     4021 ttaatacctc taagaataaa cggtaatata ttagcgttaa gtgaatttcc tgctacattt
     4081 ccacatacag tagcaacacc ttgataattt agacgtttta aaccgtataa tgttacatta
     4141 ctccccactg tatctaagaa ataatcaaaa ataccttttt taagcggttt attatcatct
     4201 tcaattatta ttacttgttt tgcacctaat ttttttgcga tttctatttg cttttctttt
     4261 cttacgatag cagtgatatt ttcatatcca attttatgta aaatttgtat agcaacactg
     4321 cccacaccac ctgtagcccc agacactaaa atttcaggtt gtgatttgat attcattcca
     4381 tatttttcta gttcaaaaat tgataatgct gccgtaaaac cggctgtgcc atataccata
     4441 gactctttaa tagacatttc ttggggaata ggaacaatcc actctccagg cacttgtgca
     4501 tattctgaaa atccacctgt atgtgtcacg ccaacatcat aaccagtaac taatacatta
     4561 tcgccttctt taaacttatc attcgaactt gattcaacaa tacctgcaaa atctatacca
     4621 ggaatcatag gataatctct aattacaccg cctttatatt gtaaagctag catatcctta
     4681 taatttattg aagagtatac cacttttact aatacatcac ccttcgataa atgagattca
     4741 tcaacttttt ctactttata actaacattt gatgcacttt ttctcactac taccgcattg
     4801 aacatttatt agccttcttt cacaattgtt ttgtagaagt atgtttttgt tgcaaaacta
     4861 ttttcctaca aaacttatca tgatatgata agcgagtcaa tactaatgat ttaagagagg
     4921 ttttagttgt ggaattagat aattgtataa attatttgtt gagtacttct cagaatagag
     4981 tttttaaaca ttttaaaagt ttattaagtc cctataatat tactccagca gaatatggtg
     5041 ttttgaattg cttgattaat agtaatttga atacacctaa agcgattggt aatactttaa
     5101 atttagaacc ttcaacaata tctggaatat tagataagat gtccaaaaag gatctaataa
     5161 cacgtcaaac tgataatgaa aatagaagaa ctgtgctaat aaacagtaca aataaagcaa
     5221 aagacttatg gccaacatta gaaaagaaag cctatcaact taataatcat tacttcgcta
     5281 atttaactaa tgaagaaact gtagtgttta aaaagatatt actaaagata aataaaacta
     5341 cgttttaatt tttacgttat aaaaaagttg aagtgcgaat tataatcgag taaatataaa
     5401 tgatagctta gcttaattat atattaaagc caactatact tttattcccg aaaaacctac
     5461 tatccaaatt tctaagatac tttagcctct ataataaaca tattgtaata taatttatgt
     5521 attatttagg tttaccctaa tcgaacaata aaaaatactt gtaaaatgct attgtcactt
     5581 tgcttgatat atgagaatta tttaacctta taaatgagaa aaaagcaacg cactttaaat
     5641 aagatacgtt gctttttcga ttgatgaaca cctataatta aactattcat ctattattta
     5701 tgattttttg tatatacaat atttctagtt tgttaaagag aattaagaaa ataaatctcg
     5761 aaaataataa agggaaaatc agtttttgat atcaaaatta tacatgtcaa cgataataca
     5821 aaatataata caaactataa gatgttatca gtatttatta tgcatttaga atattaaaat
     5881 tccttcatta cactcttggc ggtttcactt atcaacttat catttggctt atcactttta
     5941 ttgtctttat tcgtaaaaat gactaaaaca ataggttcag attggccctt aggataaaca
     6001 aaagcaacat catttctaga agcatatgtt attgcttgac cacttttatc agcaacctta
     6061 tagtcttttg gaacaccatc tttaattaaa gtgtctccgt ttttattatt aaacattaaa
     6121 tcaagtaaga aatttttatt ttttttgctt aattttccat ttgcgataag tttatttaaa
     6181 gtcttgccga aagcagcagg cgttgaagta tcttttttgc tctttggtga atagtaattt
     6241 aattctatct catatctaac tggatttgtt actttatctc ctagttcttt tagacgttgt
     6301 ttaacttttt tgattccacc gatttctttt ataattttat tgtttgctgt attatcacta
     6361 tatgtcattg aagcctcaat aagttctttt aaagtgatat cttttcctac atatttttct
     6421 aaaataggag aataagcaac tatatcatct ttgttaatat gtactttttt atttaactta
     6481 ttataaggta cttgttctaa caaaatagca ctatttatcg cttttgaagt cgaagcatag
     6541 gcaaatctct tatctgaatt aaattttact tccttaccac ttttagtatt taaagcataa
     6601 acaccaatat gagcattata ttttttttct aaatcattta actctttggc atgtgaactg
     6661 tttgaattac atgcacttaa aactaaagca attacaatta aaaatattaa ctttttcaaa
     6721 ataaaccctc cgatattaca gttgtaattt ttataaatca ataatattac aattgtaata
     6781 ttgatgtcaa ttgtttatta taaatatttg aaagaaggtg tcaaaatggc taaattacta
     6841 ataatgagcg tagtaagctt ttgttttata tttctattgt tagtattttt taggtacata
     6901 ttaaaacgct attttaatta tagtttaaat tataaagttt ggtatctaac tatgcttgct
     6961 ggattaattc cttttatccc aattaaattc tcttttataa aatttaataa tgtgaataat
     7021 caagcgccca cagttgaaag taagtcacac gatttgaacc ataacataaa taccaccaaa
     7081 cctattcaag agttcacaac agatatccat aagtttaatt gggattcaat tgataatatc
     7141 tgcacagtta tttggatagt tttagttatt attttaagtt ttaaattttt gaaagcctta
     7201 ttatatctta aatatttaaa gaaacagtca ctttatctaa acgaaaatga aaaaaataaa
     7261 atagatacga tacttttcaa ccatcaatat aaaaaaaata ttgtgattcg aaaagcagag
     7321 gctattcaat ctccaataac tttttggtat gggaaatata ttattttgat tcctagttca
     7381 tattttaaaa gtgtaattga taaaagacta aaatatataa tactgcatga atatgctcat
     7441 gctaaaaata gagatacttt acatttaatt atctttaata tcttctctat tattatgagt
     7501 tacaatccat tagtacatat tgtaaaaaga aagataattc atgacaatga agtagaagcc
     7561 gatagatttg tccttaataa tattaacaaa aatgaattta aaacttatgc ggaatctatt
     7621 atggactccg tattaaaaac cccattttcc aacaaaaata tattaagcca ttcatttaat
     7681 ggtaaaaaat cattactcaa aagtagatta attaatataa aagaagccga tctgaaaaag
     7741 cagtcaaaat taattctaat ttttatttgt atttttactt tttttatcat gataattcaa
     7801 agccagtttt taatggggca atccttaact gattataatt ataaaaagcc cttacaaagc
     7861 gattaccaaa ttttagatga aagtaaaaat tttggttcaa atagtggatc tttcgttatg
     7921 tacagcatga agaaagacaa atactatatt tataatgaaa aagaaagtag aaaaagatat
     7981 tctcctgatt caacttacaa aatttattta gcactgtttg gacttgaccg tcatattata
     8041 agtgataaaa attcacgtat gtcatggaat cataaacatt atcttttcga gtcttggaat
     8101 aaggaacaag atttaaatac agcaatgcaa aattcagtta attggtactt cgaacgtatt
     8161 agtaatcaaa taccaaagaa ctatactgcg gctcaactca agcaattaaa ttatggtaat
     8221 gaaaatttgg gaagttataa aagctattgg atggaagata gtttgaaaat atctaatctt
     8281 gaacaagtaa tagtttttaa aaatatgatg gaacaaaata accattttag taaaaaagca
     8341 aagaatcaat tatcttcttc attattgatt aagaaaaatg aaaagtatga actgtatggg
     8401 aaaacaggta caggtatagt aaacgggaag tataataatg ggtggtttgt aggttacgta
     8461 attacaaatc atgataagta ttattttgct acacatttat cagatggaaa cccgtctggg
     8521 aaaaatgctg aattaataag tgaaaaaata ttaaaaggaa tgggtgtttt aaatgaccaa
     8581 taagcaagtt gaaatatcta tggctgaatg ggatgttatg aatataatat gggataaaaa
     8641 atcagtatca gctaatgaaa ttgtagttga aattcaaaaa tataaagaag ttagtgataa
     8701 aacgattaga acattaatca caagactata taaaaaagag attataaaac gatacaaatc
     8761 agaaaatatt tatttttact catcaaatat taaagaagac gatattaaaa tgaaaactgc
     8821 taaaaccttt cttaataaac tgtatggagg ggatatgaaa agtttagtgc tgaattttgc
     8881 gaaaaatgaa gaattaaata acaaagaaat tgaagaattg cgagacattt taaatgatat
     8941 tagtaaaaag taattagagg tatgtttcaa acataataca tatgtaaacc atacttgact
     9001 cttattaaat tagttttgtt aatgacattt aaaatatatt attaaagatg agagtgtcca
     9061 gaaaataacc attttctgta cactcttgtt ttttgtctaa ataagtaagt attacataga
     9121 attatgtgtt caaaaaccca acaaaaaatc tatgttcaca aaagacctcg taatcaagtt
     9181 atggtacact aaaggtgtat ataggaggtc tgtattttga aaataggtta tgcaagagtt
     9241 tcaactggat tacaaaattt gaatttacag gaggatcgat taaatacata tggttgtgaa
     9301 aagatattta atgaccatat gagtggttca aaaagtaagc gacctggttt agataaagca
     9361 attgaatttg cgaggtcagg agatacgatt gttgtttgga gattagatag actaggacgg
     9421 aacatggagg atttaatcac gttagttaat gaacttaacg aacgaggtgt gagttttcat
     9481 agtttagaag aaaatataac gatggataaa tcaagttcta caggacaatt attatttcat
     9541 ttattcgcag catttgcaga gtttgaacgt aatttaattt tagagcgatc atcagccggt
     9601 cgaattgcag cacgtgctag aggccgatat ggaggtagac ctgaaaaatt aaataaacaa
     9661 gatttaaact tacttaagac actttatgat aatggtacgc caattaaaac aattgcagag
     9721 cagtggcaag tttcacgtac aactatttat cgttatctca ataaattaga ggcaaaagag
     9781 aataaaaaca agtagagcaa ctaatctagc ttactataat gaatctacta aataatttta
     9841 tatatcatta acatacaaag actttgattc aatgtcactc gatgtaaaag agacgttctg
     9901 acagcgtcta aaatctcata atattttcct gttatgagat tttaataata acacaagaaa
     9961 aaagcgtaca aattcgtacg cttttttaat ataatacctg tttcactaat gaacgtttta
    10021 agtatcttca tcattaactg aaactacagt aataatactc gtcaacaata ttagtatagt
    10081 taaaatagaa agacttagga ctggcataac cgaactaaaa ttatatttga aatataaaag
    10141 tgctaatgaa gagagaaatg taaaaataat aaataccaaa gaccattttt ctaatttatt
    10201 cattggcttc acctctttga acttttatat aatcatagga gatattttta ctacgattta
    10261 taaaaaataa gaagataatc attattaaag aaacgattaa tataatgttg aatcctatag
    10321 tatcacctaa ttcgtttaca cctttgccta atatcggaga tacaaagctt tgtattaata
    10381 atgaaagaga tgcccatata gtaaatgagg ttctgttgca aagttgaatt tatagtataa
    10441 ttttaacaaa aaggagtctt ctgtatgaac tatttcagat ataaacaatt taacaaggat
    10501 gttatcactg tagctgttgg ctactatcta agatatgcat tgagttatcg tgatatatct
    10561 gaaatattaa gggaacgtgg tgtaaacgtt catcattcaa cggtctaccg ttgggttcaa
    10621 gaatatgccc caattttata tcaaatttgg aagaaaaagc ataaaaaagc ttattacaaa
    10681 tggcgtattg atgagacgta catcaaaata aaaggaaaat ggagctattt atatcgtgcc
    10741 attgatgcag agggacatac attagatatt tggttgcgta agcaacgaga taatcattca
    10801 gcatatgcgt ttatcaaacg tctcattaaa caatttggta aacctcaaaa ggtaattaca
    10861 gatcaggcac cttcaacgaa ggtagcaatg gttaaagtaa ttaaagcttt taaacttaaa
    10921 cctgactgcc attgtacatc gaaatatctg aataacctca ttgagcaaga tcaccgtcat
    10981 attaaagtaa gaaagacaag gtatcaaagt atcaatacag caaagaatac tttaaaaggt
    11041 attgagtgta tttacgctct atataaaaag aaccgcaggt ctcttcagat ctacggattt
    11101 tcgccatgcc acgaaattag catcatgcta gcaagttaag cgaacactga catgataaat
    11161 tagtggttag ctatattttt ttactttgca acagaaccag catttgtttt aatatttgtt
    11221 ccaaagagcc atcatggctt tgacagagct cttcttctat gcaaatgctt ttaatccgat
    11281 ccacacgaaa attcctatat tcatttctta gcctgcaaaa ccgattaagt accagttctg
    11341 ttcataaaac cccagtgata taggctctat cattctgctt tccggttctt gccctcctga
    11401 tgcaggatat tgaattgata ttaccctttt attgcagatt gcagtctgaa ttgctgcaat
    11461 aacgttatcc gccaatgtat ttttctgtcc agatgtgctg tacacgttaa tactgttctc
    11521 caactcctgt gcatagtttt tttcaccatg cttcaaaata gatttgattt tatacatagc
    11581 tgaatcaaaa tcctttataa atgattcatc tccatggcaa tttaaaaatt tccctgctgt
    11641 aatcaatgca cccacttccg ccgctgtaaa cattaccggc agaagtagga agccctctac
    11701 aagaaaatat ccttttccgg cctcagatcc aattggtatt ccggcttctt caagtgtccg
    11761 gatatctctg taaactgtcc ttaagcttat attaaatcgc tgtgcaattt ctttggcagg
    11821 aattattttt ttgattgcag ctgaataaga atagaggtta ctctgttaat cctgttcaaa
    11881 ttttattcct cctctgtgac ttccataaaa agtatatcct atgcgttctt aagctagctg
    11941 ctgttagtgc ttctcattgc accctggtta taaaagccat actcacaaac ctcttcacca
    12001 aaactcttta catctctaat atagaactct atctagcgaa cttttagaaa agatataaaa
    12061 catcagagta tggacagttg cggatgtact tcagaaaaga ttagatgtct aaaaagcttg
    12121 tagttaaagc tttttagaca tctaaatcta ggtactaaaa caattcatcc agtaaaatat
    12181 aatattttat tttctcccaa tcaggcttga tccccagtaa gtcaaaaaat agctcgacat
    12241 actgttcttc cccgatatcc tccctgatcg accggacgca gaaggcaatg tcataccact
    12301 tgtccgccct gccgcttctc ccaagatcaa taaagccact tactttgcca tctttcacaa
    12361 agatgttgct gtctcccagg tcgccgtggg aaaagacaag ttcctcttcg ggcttttccg
    12421 tctttaaaaa atcatacagc tcgcgcggat ctttaaatgg agtgtcttct tcccagtttt
    12481 cgcaatccac atcggccaga tcgttattca gtaagtaatc caattcggct aagcggctgt
    12541 ctaagctatt cgtataggga caatccgata tgtcgatgga gtgaaagagc ctgatgcact
    12601 ccgcatacag ctcgataatc ttttcagggc tttgttcatc ttcatactct tccgagcaaa
    12661 ggacgccatc ggcctcactc atgagcagat tgctccagcc atcatgccgt tcaaagtgca
    12721 ggacctttgg aacaggcagc tttccttcca gccatagcat catgtccttt tcccgttcca
    12781 catcataggt ggtcccttta taccggctgt ccgtcatttt taaatatagg ttttcatttt
    12841 ctcccaccag cttatatacc ttagcaggag acattccttc cgtatctttt acgcagcggt
    12901 atttttcgat cagttttttc aattccggtg atattctcat tttagccatt tattatttcc
    12961 ttcctctttt ctacagtatt taaagatacc ccaagaagct aattataaca agacgaactc
    13021 caattcactg ttccttgcat tctaaaacct taaataccag aaaacagctt tttcaaagtt
    13081 ggcgtataac atagtatcga cggagccgat tttgaaacca caattatgat agaatttaca
    13141 agctataagg ttattgtcct gggtttcaag cattagtcca tgcaagtttt tatgctttgc
    13201 ccattctata gatatattga taagcgcgct gcctatgcct tgccccctga aatccttaca
    13261 tacggcgata tcttctatat aagcgtaccg gttccaattt tttcgcagtt taacttttcc
    13321 gacgcattta tcgtcttggt agtaaagata tattatctta tcagtattgt caatatattc
    13381 aaggcaatct gcctcctcat cctcttcatc ctcttcgtct tggtagcttt ttaaatatgg
    13441 cgcttcatag agtaattctg taaaggtcca attctcgttt tcatacctcg gtataatctt
    13501 acctatcacc tcaaatggtt cgctgggttt atcgatatct ttcaggtgcc ctgctttcat
    13561 ttctgtaatc actgttcccg cctctcttct atatcagcgg catatgtgct atccaggcag
    13621 ccggttttac cagtgtattt tttatacatg tccctggtat attttgttat attcctatca
    13681 tactccggat aggcataatg aagcctttcc gccacctcac cggataccgc cctgaacaat
    13741 tgatggcata gaaataatgc ttcccatatg ttttcatagg aatccatccg gtaggtggac
    13801 aaaagtttct cccacaaatc ctcggatata tacctttcaa taaacttata gttcttgcct
    13861 acacttcatt taaagcctgt ttcgatgccg accttccatg atatcattct cagcagctca
    13921 tggcgaacaa tctgattaaa atgatcaata gcaaataaaa tttccttacg gcacaatcct
    13981 ttaataacat aaggtgttac attccaaaat tcattgcagc aatcatcata ctcccttgcg
    14041 cttggctttc ttacatgata atctatatca gtcggaacta tgtccctttt aattctacaa
    14101 tctttatcaa ttagaacctt tattaattta tcgcccttta ggtaattatc taactcttcc
    14161 aagggcaata aggtaagatc aattttattg taatcatcaa atagctataa tagatttaga
    14221 ggtaaagaaa ttaaatacat tgaagagcag aaagatttta caaaagagta ttttaataaa
    14281 aatgatggtt ctgttgcaaa gtaaaaaata tagctaatca ctaatatatc atgtcagtgt
    14341 tcgtttaact tgctagcatg atgctaattt cgtggcatgg cgaaaatccg tagatctgaa
    14401 gagacctgcg gttcttttta tatagagcgt aaatacactc aatacctttt aaagtattct
    14461 ttgctgtatt gatactttga taccttgtct ttcttacttt aatatgacgg tgatcttgct
    14521 caatgaggtt attcagatat ttcgatgtac aatggcagtc aggtttaagt ttaaaagctt
    14581 taattacttt aaccattgct accttcgttg aaggtgcctg atctgtaatt accttttgag
    14641 gtttaccaaa ttgtttaatg agacgtttga taaacgcata tgctgaatga ttatctcgtt
    14701 gcttacgcaa ccaaatatct aatgtatgtc cctctgtatc aatggcacga tataaatagc
    14761 tccattttcc ttttattttg atatacgtct catcaatacg ccatttgtaa taagcttttt
    14821 tatgcttttt cttccaaatt tgatataaaa ttggggcata ttcttgaacc caacggtaga
    14881 tcgttgaatg atgaacgttt acaccacgtt ctcttaatat ttcagatata tcacgatagc
    14941 tcaatgcata tcttagatag tagccaacgg ctacagtgat aacatccttg ttaaattgtt
    15001 tatatctgaa atagttcata cagaagactc ctttttgtta aaattatatt ataaattcaa
    15061 ctttgcaaca gaacctccta actgtattac caccttaaaa gtagttgcag acgcacttcc
    15121 taaatcgtca gcagtgttta accacatatc atcaacaata atcatatgac ctgttgatga
    15181 tactggagca aattctgtca acccttcaac tacacctaaa ataaatgctt taatctgctc
    15241 tataaaaccc atttttctcc tccttttaac ttatatcagt ttttttaaag tatgagaata
    15301 atataattac actgaatata gatgtaacaa ttatgataat taaagataat agaaatggat
    15361 aagtattagg taatgttcct ctagatatgt ctccaactgc agcccaagga aataatcctc
    15421 tatgttcaga attagcagtc attaaattta tcaaagtaat tattatggtt aaaacaattg
    15481 tgggaacata atttttaaaa tatatcgaca aaataattat tggtggagat aatatccata
    15541 ataacactcc gccaataaca aatgtaaaga atgaatcaat tattaaactc tggcttaacc
    15601 cttgaaaatg caatagcata cctagcatta aagttagcaa ccatgcaata acagatagtg
    15661 tttgaatcca caagaataat aatattattt tacttactaa aaaactttct ctagatatag
    15721 gtataattaa taagtttttt aaagtatctt ctatatattc tcttccaaac aaataggcta
    15781 ttataacccc atatagagga ggtccaataa ttagcatatg atataaactg acttcttcaa
    15841 ataactgttt aaatacaata ttaggagtcg gtactttcgt ccgcatacta ataaaagaag
    15901 ctacaaccac cataaaaggt gctacgcatg tacctaaaat acttattaga aacatatatg
    15961 atctttttaa cttaataaat tctgtacgga gtagattatc caattgtgcc acctcctact
    16021 aagtcttcga aataagtttc tagattatct tctatcactc tcatctggaa aacatcaata
    16081 ttgtttaata ctaataatct attaatttct tgttgtctat caatatgtga ataaatttta
    16141 aattcgccat tttctttaat tttatagtca taaattccga agttagtttc caacaaacat
    16201 gcaacttttt cttcatctga tactgatata cttataaatt gtctgttctt tttttttaaa
    16261 tcttcataca taatttcttc taacaaaact ccgttatgaa taatacccac cttgtctact
    16321 aactgctcta tttctgacaa tatatgactt gaaattaaaa tggttatatt tctagattga
    16381 gccagatcct taatcaactt tctaatttct tttatgccaa taggatctaa tccattcgtc
    16441 ggctcatcaa gtatcaataa ttcgggattg tgcaataaag ctctcgcaat ccctaaacgt
    16501 tgcttcatac ctaaagaata atttttaaac aattttactt tttcagaagc tagtcctact
    16561 atttctaaca cttcttcaat tgcattttct ttttgtatac ctaatatttt agcatttata
    16621 gttaagttct ctttagctgt caaattacta taaaaacctg gcgtttcaac catagcacca
    16681 atatttttta aaatttcagt tttattactt tcgaactctt tttcaaatat tttaatatta
    16741 cctttcgtag gtttaattaa gcctaaaagc attcttatag tagttgtttt gcctgcacca
    16801 tttcttccta aaaaaccata aatttgtcca ctttcaacag ttatactcaa attattaact
    16861 gctatctgac ttccatattg ctttgttaag ttatttattt caattatatt attcaaattt
    16921 ttcacctctg gcacctttct tagtttgttg ttacctttat cttacgcgcg attagaaaag
    16981 gctgccttta tctattctta caaaaacagc cgctaatctt acaaaaatga aagattggag
    17041 ttatttaaat tgaatggtga atattgaacc atcgtttaat gtagatgtag cacttacttt
    17101 atggcctaag cgctttgaga ttgtgctgac aatatataaa ccaataccgc ttgatttctc
    17161 acttattcta ccgttatagc ccgagaaacc tttatcaaag attttcggta aatcactcgc
    17221 attaatgccg ataccgttat ctcggattga taatttcttt gtattttcgt caaacgtaat
    17281 ccacacatct ttgccacgtg catattttaa tgcattgttt aatatttgct caatcataat
    17341 tgatgcccat ttggcatctg ttaatataac cgcttcactt ttctcataat gcaactttgt
    17401 ttgatgatga ataaactgta tcgcataacg tttaatcagt ggtcgaatta attcatctac
    17461 actcacttcc ataaagacca tgtatgtctt ttggttcatg agtttcaaat agttcagtgc
    17521 aagattcgtg taattatcaa tttgtaagac ttcattacgc acgttagaaa tcacgtgttc
    17581 atcaggatct tcaagcagta actttgatgc tgtaatcggt gtcttgattt gatgcaccca
    17641 cattaaaaaa tatgactcta actcactttg gtagttaata aagtcattac gaagtttatg
    17701 gttttcgatt cttaaatctt cgttctgttc ctgtagtgtt tattcttttt taaagttcat
    17761 gtaatggata ccccagtaaa tcattgaaac aaacaataca atacctagac caatcatata
    17821 tgcttgcatc ggcacattat acatgaataa tataaagtag aataaagcac aagtaaggat
    17881 gacaatataa atttcacgtt ggattgattt caagaaattc atacgtcacc tacacgatat
    17941 ccgacatttt tcttcgtttc gataaaatct gtaagtccta gtttttgtag ctttttgcgt
    18001 aaacgtgtaa tgttgacagc aagcgtattg tcatcaatga agtgttctga ttcccagcat
    18061 ttttcgatta acgcattacg actgacgaat ttgcccttgt tctggaataa gctatgcatg
    18121 atttgcaatt cagtgtgtgt caggtctatg gtttcttcat taaatttaag ctttgctgca
    18181 tcaagtagta actcgcaatc atctactgtt aaattattaa cttgagtggt gaaatcatac
    18241 gtgcggcgta atagtgcttg aatcttagta attgtaacag tcatattaaa tggctggttc
    18301 tgttgcaaag taaaaaatat agctaatcac taatatatca tgtcagtgtt cgtttaactt
    18361 gctagcatga tgctaatttc gtggcatggg gaaaatccgt agatctgaag agacctacgg
    18421 ttctttttat atagagcgta aatacattca atacctttta aagtattctt tgccgtattg
    18481 atactttgat atcttgtctt tcttacttta atatgacggt gatcttgctc aatgaggtta
    18541 ttcagatatt tcgatgtaca atgacagtca ggtttaagtt taaaagcttt aattatttta
    18601 gccattgctg ccttcgttga aggtgcctga tctgtaacta ccttttgagg cttaccaaat
    18661 tgtttaatga gacgtttgat aaacgcatat gctgaatgat tatctcgttg cttacgcaac
    18721 caaatatcta atgtatgtcc ctctgtatca atggcacgat ataaatagct ccattttcct
    18781 tttattttga tatacgtctc atcaatacgc catttgtaat aagctttttt atgctttttc
    18841 ttccaaattt gatataaaat tggggcatat tcttgaaccc aacggtagat cgttgaatga
    18901 tgaacgttta caccacgttc tcttaatatt tcagatatat cacgatagct caatgcatat
    18961 cttagatagt agccaacggc tacagtgata acatccttgt taaattgttt atatctgaaa
    19021 tagttcatac agaagactcc tttttgttaa aattatatta taaattcaac tttgcaacag
    19081 aaccgtattt tatgagtaca ctctaaatta aggagatgta taatcaatct aaaattgtat
    19141 ttttatactt ttgttatata atctttctac ttagagatat attgtaaaaa aaccaacaaa
    19201 atgttatatt aacattacta ttttatcgat gaaggaggat taaaatgaca gcttctatga
    19261 gactcaaata aacctttttg aatacaaaac taaattaatt caaaaaggct tgtccgcaat
    19321 acacactcat aggatgactt atgtcatttt ttatccttcg ataggaataa taaacgcttt
    19381 caaatactaa aacatcataa taaattttta agtgtttgaa agtgtaatgt gaatgagacg
    19441 ggagtagcct gtctcatttt tttgcgtaca cgtcctttaa atatacaagg agtgtataaa
    19501 tatggaacaa tatacaatta aatttaacca aatcaatcat aaattgacag atttacgatc
    19561 acttaacatc ggtcatcttt acgcttacca atttgaaaaa atagcactta ttgggggtaa
    19621 tggtactggc aaaaccacat tactaaatat gattgctcaa aaaacaaaac cagaatctgg
    19681 aacagttgaa acggttggcg aaattcaata ttttgaacag cttaacatgg atgtggaaaa
    19741 tgattttaac acgttagacg gtagtttaat gagtgaactc catataccta tgcatacaac
    19801 cgacagtatg agtggtggtg aaaaagcaaa atataaatta gctaatgtca tatcaaatta
    19861 tagtccgata ttacttttag atgaacctac aaatcacttg gataaaattg gtaaagatta
    19921 tctgaaaaat attttaaaat attactatgg tactttaatt atagtaagtc atgatagagc
    19981 acttatagac caaattgctg acacaatttg ggatatacaa gaagatggca caataagagt
    20041 gtttaaaggt aattacacac agtatcaaaa tcaatatgaa caagaacagt tagaacaaca
    20101 acgtcaatat gaacagtata taagtgaaaa acaaagattg tcccaagcca gtaaagctaa
    20161 acgaaatcaa gcgcaacaaa tggcacaagc atcatcaaaa caaaaaaaca aaagtatagc
    20221 accagatcgt ttaagtgcat caaaacaaaa aggcacggtt gagaaggctg ctcaaaaaca
    20281 agctaagcat attgaaaaaa gaatggaaca tttggaagaa gttgaaaaac cacaaagtta
    20341 tcatgaattc aatttcccac aaaataaaat ttatgatatc cataataatt atccaatcat
    20401 tgcacaaaat ctaacattgg ttaaaggaag tcaaaaactg ctaacacaag tacgattcca
    20461 aataccatat ggcaaaaata tagcgctcgt aggtgcaaat ggtgtaggta agacaacttt
    20521 acttgaagct atttaccacc aaatagaggg aattgattgt tctcctaaag tgcaaatggc
    20581 atactatcgt caacttgctt atgaagacat gcgtgacgtt tcattattgc aatatttaat
    20641 ggatgaaacg gattcatcag aatcattcag tagagctatt ttaaataact tgggtttaaa
    20701 tgaagcactt gatcgttctt gtaatgtttt gagtggtggg gaaagaacga aattatcgtt
    20761 agcagtatta ttttcaacga aagcgaatat gttaattttg gatgaaccaa ctaatttttt
    20821 agatattaaa acattagaag cattagaaat gtttatgaat aaatatcctg gaatcatttt
    20881 gtttacatca catgatacaa ggtttgttaa acatgtatca gataaaaaat gggaattaac
    20941 aggacaatct cttcatgata taacttaaaa actatacact aatttatatt gaatattagg
    21001 ttcatttata tcaatataaa aaatacgttc acaagaaaaa tataatagaa ataaggatcc
    21061 aataaaatga ctcgacataa tgaaattatt aaatgtgcag aaaaatatca attacacatc
    21121 caacctcaaa caatctcatt gaatgaatcg ggacttgatt ttcaagttgc atttggaaaa
    21181 gataaacatg gagtagaatg ggttttgaga ctaccaagaa gacctgacgt ttataaacga
    21241 acaaaacccg aaaaacaaac ggtagacttc ttacagaaga atgtttcatt tgaaataccg
    21301 aagtggaaag tacatgcaaa agaccttatt gcttacccaa aacttacagg taaacccgca
    21361 gccacaatag atccagaaat acaaaattat gtatgggaaa ttgaacacaa accattacca
    21421 gaaaacttta ttaacacatt agctgaaaca ctcgtagatt tacacaacat accagaagaa
    21481 aacattaacg ttcagcatat aaatatcaaa accatacaag aaataaaaaa tgactttcaa
    21541 agaagaatga ataaagttaa agaaacttat ggcgtatcag atgaattatg gaacagatgg
    21601 aaacaatggt tagaaaacga cgaactatgg cctcgacatg cgaccatgat acatggggac
    21661 ttacatccag gacatataat ggtagataac caagcaaacg tcacaggtct catagactgg
    21721 actgaagcaa cccactccga cccatcaatg gactttatag gacaccatcg tgtattcgac
    21781 gacgaaggat tagagcaact tataacagca tacggtaaag ctggaggtga aatatggcca
    21841 cgaatgaaag agcatataat agaactcaat gcagtattcc caatgtttat cgctgagttt
    21901 gctatggaat caggagaatc ggcgtatgaa acgatggcat tgaaagagtt aggtatgaaa
    21961 gagtagaact tatattaaaa gaggcccatt ttaaagacga aggcaatcct gatgaaattt
    22021 taaaactgcg tttaattagt gatggtcttt ggttttctat aatgtattaa atatctggac
    22081 atggaacaaa tgcaacaaat ggaaagaatc gttttcgaaa tttctaactc cttaaatcag
    22141 gaggataaat aaacggtcat tttcattgaa agcacttata taaatttcat caattttaat
    22201 acctaccgta aatacatttc ataagtatta aacagatgat taaaattttt agttaattta
    22261 aatatttatg atagagatga ccttcaaatg aacggttctg ttacaaagaa aaaatctata
    22321 tttattttta gtaagtttta attatagata tgtacacttt gagtacaccc taaccataca
    22381 aaaagaattg ttgaaattat aacaattaaa acgtatgatt agggtgtata tttattatgg
    22441 agtgaagatg aatgattata ggttatgcga gagtatcatc gatagatcaa aatttagaaa
    22501 gacaattgga taatttaaag acgtttggtg tggagaaaat ctttacagag aaacagtcgg
    22561 gaaagtcagt ggaaaataga cctgtatttc aagaagcact caattttgtc agaatgggag
    22621 atcgattcgt tgtggaatct attgatcgtt taggacgtaa ctatgatgaa attattgaaa
    22681 ctgtgaatta tttaaaagaa aaagacgttc agttaatgat taccagctta cctatgatga
    22741 atgaagtaat tggcaatcca ttactggata agtttatgaa agatttaatc attcaaatat
    22801 tagcaatggt ttcagaacaa gagagaaatg aaagtaaacg tcgacaagcg caagggattc
    22861 aagttgcgaa ggaaaaaggc gtatataaag ggcgcccttt actttattca ccaaatgcta
    22921 aagacccaca gaaacgtgtt atttatcatc gcgtggtgga aatgttagaa gaaggcaaag
    22981 cgattagtaa gattgcgaaa gaagttaata tcacaagaca aacagtttat agaattaaac
    23041 atgataaggg attatcttga taaattgatt gtcaatgcaa atgagcgtct ctcacagtgt
    23101 ctcaaattcc ataacatatt attgaattga gattttaata attatacaag aaaaaagagt
    23161 acgagttcgc agctttctat atagtaattg ttttactaat aaggtgtttt aaaatatatt
    23221 ataatgtaaa aagtatttga catttgtatc aaaaatattt acactcataa atgtcaaata
    23281 ctttttacat ttatgaggtg ttataatgaa tttaattcct tttattatta ttttaatttt
    23341 ttcttgttta tggacggcta taactaacaa atatttacct tcagaaacat tagataaaaa
    23401 aggacaacaa gatcgatacg atgaaagaca acgtaaaatg tttattgaaa tactggctaa
    23461 aagttttatt tggattgtat attgtatgtt atttacacta gtgcttaaat ttacaggttt
    23521 gtcaccaagt attgaaggat cttggttttc tcaatatcca gaaattttct ttataattgt
    23581 agcactattt cttatgctgt ttaattacta tactacaaat aaaaaatata catctaaagg
    23641 ttaaattaat gaaaaataga attagagaat atagaaaaca aaaaggaatt tctcaagaaa
    23701 ctttaagtaa agaattaaaa gtgtctaggc aaactattaa tgcaatagaa aacaataaat
    23761 atgatcctac attgacatta gcatttaagt tggcaagatt gtttgataca actgtggatg
    23821 aattattttc ttaaccattc atttatcaca aaaagagagt gcgaattcgc actctctttt
    23881 tgtgtagtag tactattaaa ttttgtctca ataacgaacg tttataacgc aatcatgatg
    23941 agagtattaa tacagttaat tatttgaaat actttagttt acataatcga tgattaccag
    24001 aagttctcac tatataaaag acactaaaat tttataactt ttagtgccta atcaattatt
    24061 ttagctacca aacaaacgac tccaaaaccc ctttttaggt tccgtttctt cactcttttc
    24121 ttctatatca ctatcattgt catttagatt agctggaacg tcttcttttt ttgcttcttc
    24181 accttgtgta ctttcgtcgc tttgacttcc agatatatcc ttatattgaa tctctgtttc
    24241 tttagtttct tcctgatctc tgttaatatt tacaggatta gtagtatatg ttttttcttg
    24301 tgcatcaacg ttttgtctag tgttagtaga tgtatcaaag ggataattaa ggtgtttttc
    24361 tttttctaat tgattttcta atttttgaat ctttttatta ctctctaatg ccagaacttg
    24421 ctgattttca agcaattttg atctttcttg caactctttt ctgtaaaatt caattgttgt
    24481 ttcatgacga ctttcttgtt tttcaatttg attatttaaa gtatcaatct gatttttaag
    24541 gatttctact atttgagcat cgcttttcga ttcaaaatta atattatccg accctttttt
    24601 ttgtttgtct tcagtagtac tttcaaaacc atatttcttt ttattttcat ttactctttg
    24661 aatgattttt tctatatcgg tatcttcttt aataaacgaa gtgttttcct gttttattgt
    24721 ctctatattc aatcgcttaa tattattaaa aatcgtttgc ttactaaccc ctaattcttc
    24781 actcaacttt ttcacacttt tcatatcatc aaccctttat aaaatgttta taaacccttg
    24841 ataaaatatt ataagcttat aatgcttaat aataaagtga ttaataaata aaaataaaca
    24901 tccatcaacc tttttatcaa gggtttataa acccttgata aagctatatt ttccctttta
    24961 taagtttatt taaagtgcta taataaactt aatataacaa aaaccccaac tactggtaat
    25021 agtcggggtt tggtaataaa acgtttagaa actgtttatt tatataattt tcgatacttg
    25081 tattatataa tgaataatat cttagtgcaa gcacctaaat cattaaataa atgtaaagct
    25141 aaataaaaac gttttattac ctcttaccaa actaaaatat ggaaagaggt tttttgtcat
    25201 gcaaaatcaa tattttacag tgcaagaaaa ttacaaagaa agattttatc aaatccctaa
    25261 agtattcttt accagtgaaa attataaaaa tctaactaat gatatgaaaa tagcctatgc
    25321 tatcttacgt gatcgcttaa atttatctat taaaaatagc tgggttgatg aagatggtaa
    25381 catttacttt gtttattcaa atgaaaagct aatggaaatc ttaaattgta aaaaagaaaa
    25441 gttaacaaaa ataaaaaaag ggttagaaaa cgatggtcta ctcattcaaa aacgacgtgg
    25501 tttaaataaa ccaaatattc tatatttaat gaaacctatt gtcacagaac gtgatattta
    25561 caaaatagaa aaagaagaaa acgatgttga accttacggc gagaaggaag ttcgaaaatc
    25621 gaacgtccag aagttcgaaa atcgaacgtc cagaagttcg aaaatcgaac gtccagaagt
    25681 tcgaaaatcg aacactaatg atactgactt taatgacatt gactttaatg atactgagaa
    25741 taatgatatg aatgacttga atgatataaa gtacaaaaat gaaattagta atcattcaaa
    25801 tcattcaaat caatttacac ataattttga tgataaagaa atgctattgc aagaattccc
    25861 agaacaacta actaattatt tattaaaata tgattataga gatttagaaa tcataaaggc
    25921 tgttattctt aaagcaaaaa aatcatttaa ttcaaggcat gaagatatgc attacatgtt
    25981 agaggacatt gaggatgaaa tattaacttc tttaaaaaga cttaaaaaag ctatacatga
    26041 taggggagtt aaaggccaaa aggaaacaat caagtcaatg caagcttatt taatgcaaac
    26101 aattctaact gaacttgaag aaacacatgc cctttatatg cgccgtaaaa acatgaaaca
    26161 atataatatc tttaatcaat aattcaaatg attttataac actcgaagag acatcaaaat
    26221 attccgttaa atcatctgac tttttaactg atgacgacga aaaaaatcaa gaaattgtaa
    26281 gtgatttaga aaaaggtttg tatcgaaaac gtatgttaag ttatggtgga ttgcttaaac
    26341 aaaagcataa aattttaaac ttagacgatg ccgaagatgg taatttgatt aatacaagtg
    26401 atgaagataa aacgacagac gaagaaaaaa agcacattca attaccgcaa tttggaattt
    26461 cgaaaagcaa aattattatt taagacatta gtgataactg atgtcttttt ttattgtttt
    26521 tctgtaaaaa agtgctgtct tatttttgtg acaaatgctg tatgtagtgt cacaaaagtg
    26581 tgacactaca gctttgtatg atatcacttt aaaataactt aaaacccttg gaatgtctgg
    26641 ccttgccaga tctatcattt ttgaatgata gcaaatttcc cttatgctct tacggagatt
    26701 ttagagttaa attaaaattt ctaagttttt gataagaaaa gccctgcagg aatttagaaa
    26761 aacatgggga agttttaaag tattttatgc taatttttaa atttgcatgt aaatgggcag
    26821 tatctaaaaa attagtcact gattttgctg aaatttttgt ttgtgaaatt agcatatatt
    26881 tatttggctc atatttgcgt tttaagagac tgtatagatt tttaagtaca aaacctatat
    26941 gatttgcctc taagtcttca aaatgcctct taaaatccaa aataaaagtg tttaatattg
    27001 taataaggat tgctattttt ataaaaggag agatatc
//
