LOCUS       NZ_LR025104            21855 bp    DNA     circular CON 18-JUN-2024
DEFINITION  Escherichia coli isolate EC-1639 plasmid 5, complete sequence.
ACCESSION   NZ_LR025104
VERSION     NZ_LR025104.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA4786454
            Assembly: GCF_900497485.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Gonzaga-Molto,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JUL-2018) Leibniz-Institut DSMZ-Deutsche Sammlung von
            Mikro, Mikrobielle Genomforschung, Inhoffenstrasse 7 B, 38124,
            Germany
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900497485.1-RS_2024_06_18
            Annotation Date                   :: 06/18/2024 05:54:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,109
            CDSs (total)                      :: 4,984
            Genes (coding)                    :: 4,812
            CDSs (with protein)               :: 4,812
            Genes (RNA)                       :: 125
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 172
            CDSs (without protein)            :: 172
            Pseudo Genes (ambiguous residues) :: 0 of 172
            Pseudo Genes (frameshifted)       :: 68 of 172
            Pseudo Genes (incomplete)         :: 113 of 172
            Pseudo Genes (internal stop)      :: 30 of 172
            Pseudo Genes (multiple problems)  :: 34 of 172
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR025104.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..21855
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /isolate="EC-1639"
                     /db_xref="taxon:562"
                     /plasmid="5"
     gene            join(21596..21855,1..34)
                     /locus_tag="EC1639_RS25995"
     CDS             join(21596..21855,1..34)
                     /locus_tag="EC1639_RS25995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_166668574.1"
                     /translation="MSEIYCIAIAVIIVGYVYLMISVITAPQKLFPILQLITLIGISSL
                     FSFMSFKSESMWTGEPELLVAIMFGTFSATLIFYMFKILIRASIRHTWHCIE"
                     /name="hypothetical protein"
     gene            49..345
                     /locus_tag="EC1639_RS25315"
                     /old_locus_tag="EC1639_05126"
     CDS             49..345
                     /locus_tag="EC1639_RS25315"
                     /old_locus_tag="EC1639_05126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000040716.1"
                     /translation="MSKLNLNKRYLTLSLFMAALMLCVAEPAFADDVSTKTTGFLQKII
                     DFLTDVRKPAITIMALVIGYIALFSRQHTAWIVPLVIGIIIFIVAPYIPNWLA"
                     /name="TrbC/VirB2 family protein"
     gene            364..3117
                     /locus_tag="EC1639_RS25320"
                     /old_locus_tag="EC1639_05127"
     CDS             364..3117
                     /locus_tag="EC1639_RS25320"
                     /old_locus_tag="EC1639_05127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_109537470.1"
                     /translation="MSTLFKGLTRPALIRGLGVPLYPFLGMCIICVLLGVWIHEAMYAL
                     ILPGWYAIRRVTQFDERFFDLLYLRTLVKGHPLSNKRFSAVHYAGSQYDEVDISKVDNF
                     MKLKDQSSVEELIPYSSHITDNIIVTKNRDLLATWQIDGAYFECVDSEDLSILTDQLNT
                     LIRSFEGKSVTLYPHRIRCKKDVRPVFNSKIPFVNRVMNDYYESFPQSEFFENKLFLTI
                     CFKPFTTEDKVTHFFSRGKKQKDIFKEPVNEMNEICDRLNTYLSRFHSRRLGLYEDHGV
                     VYSDQLSLFQYLLSGRWQKVRVSSSPFYTYLGGKDLFFGNDAGQITASDHARYFRCIEI
                     KDYFQETDAGILDALMYLPVEYVVTSSFTAMDKQSAIKALDDQIDKLEMTDDAAKSLLA
                     DLKVGLDMVSSGYISFGKSHQTLVVFADSPERLVKDTNIVTSTLEDLGLIVTYSTLSLG
                     AAYFAQLPGNYTLRPRLSTLSSLNFAEMESFHNFFSGKEKGNTWGEKLITLRGSGNDIY
                     HLNYHMTTEHQNFFGKNPTLGHTEILGTSNVGKTVLLMTKAFAAQQFGTPESFPANRKL
                     KKLTTVFFDKDRAGEVGIRAMGGSYYRVKEGEPTGWNPAALPPTKRNIAFMKDLVRLLC
                     TLNSEPLDDYQNSLISDAVERLMQRSDRSYPISKLRPLIQEPDDTETKRHGLKARLKPW
                     TQGEEFGWVFDNREDTFDVDNLDVFGIDGTEFLDNKVLASAASFYLIYRVTMLADGRRL
                     LIYMDEFWQWINNEAFRDFVYNKLKTGRKLDMVLVVATQSPDELIKSPIVAAVREQCAT
                     HIYLANPKAKRSEYVDGLQVRELYFDKIKAIDPLSRQFLVVKNPQRKGESDDFAAFARL
                     ELGKAAYYLPVLSASKPQLELFDEIWKEGMKPEEWLDTYLEQANLI"
                     /name="VirB3 family type IV secretion system protein"
     gene            3128..3886
                     /locus_tag="EC1639_RS25325"
                     /old_locus_tag="EC1639_05128"
     CDS             3128..3886
                     /locus_tag="EC1639_RS25325"
                     /old_locus_tag="EC1639_05128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000744201.1"
                     /translation="MKKQIMAAFVASLIVISGAQAGIPVAIDANPEWAIEAGRWTERLK
                     QWAETVKHYENQINAYKQELLSKTGIRDVQGLVQSAQSVSQELMQIYDQGNAFIDDYIK
                     NPEGALSEQAKSLLSDYKVTDTCQNLGYSGDLVRGCEATFLSQLASVEYGNKLESKLRQ
                     DNQTMKDLIDQVKNAKDTKATQDATNAVALEQLKFEKLKFQYQMYRDKQRDLAEYKEKM
                     AQASFRKQQREAVPPSYRKAYMAMKSYEDD"
                     /name="type IV secretion system protein"
     gene            3887..4114
                     /locus_tag="EC1639_RS25330"
                     /old_locus_tag="EC1639_05129"
     CDS             3887..4114
                     /locus_tag="EC1639_RS25330"
                     /old_locus_tag="EC1639_05129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000835348.1"
                     /translation="MKSIATAGLVIISVFSLSGCFEETKSVDWWLAHPKETYKKFEECQ
                     KSGSDSDNCKNVKRAHLSFERRKAVGLPIN"
                     /name="EexN family lipoprotein"
     gene            4124..5257
                     /locus_tag="EC1639_RS25335"
                     /old_locus_tag="EC1639_05130"
     CDS             4124..5257
                     /locus_tag="EC1639_RS25335"
                     /old_locus_tag="EC1639_05130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001576910.1"
                     /translation="MGIVTGIPDGTDLSGNVTSPANAGGVPGFDSDFFQTTHEVIFNIL
                     NKSISGKLSEYSDVAYTLGKYGVSLYVLWYAFTVLARKQQTPVPDFIWNICRFYIILLF
                     VKNTGGILTSATDAIDGLKNTLAGGDPWVWMDQLWVKVIQVATLIFDKDTSTVPVAGGI
                     GALLTYVGGVLALLLCSIVFAAAELTLLLLSVTAPIFIMCLMFGFLRQMFNSWLQLNFS
                     SLLVFLFAALALRAGTWQLNMALSTSIATASENNLLQTGVTSLAAGIFMAWIIWQAKSY
                     ASQIAGVGVEGAMQGAAAMGIGAGVFGASRMARGALGMGRNAGIGAWKGLRRQEGGFGQ
                     SPGITGKTANLAGQGVNIGAKKLRQAAIERAKKMYGG"
                     /name="type IV secretion system protein"
     gene            5502..6215
                     /locus_tag="EC1639_RS25340"
                     /old_locus_tag="EC1639_05131"
     CDS             5502..6215
                     /locus_tag="EC1639_RS25340"
                     /old_locus_tag="EC1639_05131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000394613.1"
                     /translation="MEFKLPGFKNKKDVTDSSVSFEEKNIALQERMNRIYKFGGIGGML
                     IGGLSLLALNAALPLKTTVVDAYLIDKVTGVAERLTSVKKENLSENEAIARYFITQYIK
                     HREGYNFFSLQHDYDYVMAYSAENVAADYNALFNSEQAPKLVYNKAEKTAMVQDNPSVI
                     ISPSSRTDDKDIGAYIRFRLTIRDVATGQTRQEFWNVRLTYRIEPQVEMVSGERNNNPL
                     KFVVTSYVRDKEARG"
                     /name="type IV secretion system protein"
     gene            6220..7149
                     /locus_tag="EC1639_RS25345"
                     /old_locus_tag="EC1639_05132"
     CDS             6220..7149
                     /locus_tag="EC1639_RS25345"
                     /old_locus_tag="EC1639_05132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000783379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="WP_000783381.1"
                     /translation="MKMNKGALIMALLMAAHVCNAAVLPSGSRFDPRNQIVSYNPNNTT
                     IINSAVGYTTTLVFDEDETVISARTGFPQGWAVNKEDNLVYLEVRPVKQTVQKNNTDEN
                     GNTSSESVSVALDPENELERWRTNLFVRTTKRNYSMELNARTFRQPEKIAFVVNYQYPQ
                     ERRKEQAEIEKKRTETLARRLEEQAINRSLENAKSPRNWQYWKRVAEGSQDISPDYAYD
                     DGRYTWFGFSPLKKIPSVFVMNGMQETLTNPVIKQSGSFTAVGVPVDKRFVLRLGEQVV
                     GIENQGFGKVRLPAGDTVSPDVKKEVIQ"
                     /name="TrbG/VirB9 family P-type conjugative transfer
                     protein"
     gene            7146..8351
                     /gene="virB10"
                     /locus_tag="EC1639_RS25350"
                     /old_locus_tag="EC1639_05133"
     CDS             7146..8351
                     /gene="virB10"
                     /locus_tag="EC1639_RS25350"
                     /old_locus_tag="EC1639_05133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001378527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_089602783.1"
                     /translation="MTEQENKIPTATEIEQQLRERRQKELEQAGKTPEEEPGKPALQLG
                     IEKLKKSRKGMIILVVGFLLLAAGVSVYYIPSIIRSVSSGDEKPASQPLATGEAKRQTG
                     LSEDIDPFNTAQKKTEKPEEEKVISSEKTEPPENKQQSFSRALDVSLDGSQAGNSSSSA
                     GTSVSHTAASEPESDKKDEAKATAQATESAPLAKITKLPYDPNLFIPEGRSIPCSLDRR
                     FVSDLAGKLECTVNSDIYSASGNVKLIERGTAAKLMYKAGSLNHGQGRVFVMAYKLRTR
                     SKPFIDIPLVDSQAAGALGEAGASGWIDTHFSERFLGAMMVGMIPDLSQAASGIAQNNR
                     DSQTDYTANSRQAFADIAREAFSNSVNIPPTLYKNQGEIITLIVGQDLDFSGIYKLKMK
                     GG"
                     /name="virB10"
     gene            8353..9384
                     /gene="virB11"
                     /locus_tag="EC1639_RS25355"
                     /old_locus_tag="EC1639_05134"
     CDS             8353..9384
                     /gene="virB11"
                     /locus_tag="EC1639_RS25355"
                     /old_locus_tag="EC1639_05134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058463.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_001058476.1"
                     /translation="MNNENRHLIYDVVNDYFYHWLNETDGVTEIAVNRPGEIFIKVRGK
                     WQWYEQKMSYSDCLSFASTLADFHDGGSVTPEYPLRSATLPGGERVQVVIPPATEKDTV
                     SITIRKPSGIFISHDKFIKQGFYSRVSGLSGDSVMEDNISALITSGYFERVIPESLSQG
                     KTIVFCGGTGSGKTTFANACLEYIPHHLRCISIEDTDEAKFRFHKNHVKLYYPAEGESK
                     IITSASLLRSCFRMNPDRILMTEIRGAEAWDFLKASSSGHAGNITTVHESSPEYAVLGI
                     VQRCYMNPECQNLPFNVILRRVLSNIDIIMSIKYLDDEDFRFASGIYYRQLHFDDYFRK
                     LKE"
                     /name="virB11"
     gene            9387..11222
                     /locus_tag="EC1639_RS25360"
                     /old_locus_tag="EC1639_05135"
     CDS             9387..11222
                     /locus_tag="EC1639_RS25360"
                     /old_locus_tag="EC1639_05135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053816.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_000053829.1"
                     /translation="MSLKLPDKGQWVFIGLVMCLVTYYAGSVAVYFLNGKTPLYIWKNF
                     DSMLLWKIITESNIRTDIRLTAIPSLLSGMVSSLIVPVFVIWQLNKMDVALYGDAKFAS
                     DNDLKKSKLLKWETENDTDILVGAYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPNLLV
                     RKHSLIALDPKQELWKITSKVREILLGNKVYLLDPFNSKTHQFNPLFYIDLKAESGAKD
                     LLKLIEILFPSYGMTGAEAHFNNLAGQYWTGLAKLLHFFINYEPSWLNEFGLKPVFSIG
                     SVVDLYSNIDRELILSKREELEGTNGLDENALYHLRDALTKIREYHETEDEQRSSIDGS
                     FRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDISLAYDFLNLFFNFVVE
                     VTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIYQNISQLNE
                     IYGIEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGYITTTSKSTSKSRGRSASQGESE
                     SEARRALVLPQELGTLDFKEEFIILKGENPVKAEKALYYLDPYFMDRLMKVSPKLASLT
                     MELNKTKKIFGVKGLKYPSKEKMLSVGELESEVLL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            11219..11632
                     /locus_tag="EC1639_RS25365"
                     /old_locus_tag="EC1639_05136"
     CDS             11219..11632
                     /locus_tag="EC1639_RS25365"
                     /old_locus_tag="EC1639_05136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_001547184.1"
                     /translation="MKKILMISILVLTACSSPPEPPQVEWEKMPEVMNTQIMNWTPTSN
                     VIKSDNINSLWSKVLPDFKPENRLYDDSVFYAVAHSEKIVVRTSSFDSYWSAKDWLRKN
                     GATGVIEYHPLKRWLNNDYVEIYLSRINVQRLP"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            11629..11931
                     /locus_tag="EC1639_RS25370"
                     /old_locus_tag="EC1639_05137"
     CDS             11629..11931
                     /locus_tag="EC1639_RS25370"
                     /old_locus_tag="EC1639_05137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000717623.1"
                     /translation="MKKICKGLIVIFTVSCFIAPTYAADPCKSVFCLYGKAVGSSGGSE
                     CSSAEKDFFKNVEKKKGKIRWGKTFDLRKNFLNQCSTADPAAISLIMSKFGKIKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            11937..12194
                     /locus_tag="EC1639_RS25375"
                     /old_locus_tag="EC1639_05138"
     CDS             11937..12194
                     /locus_tag="EC1639_RS25375"
                     /old_locus_tag="EC1639_05138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001547185.1"
                     /translation="MKKKEKIDFLNAIKAGHSGFIAGNPAHALDDKTMNAIIHNYEATI
                     APGKAGNCKETPLTKYCSRTMPERISVEEINEVKIYPEFF"
                     /name="hypothetical protein"
     gene            12276..12710
                     /locus_tag="EC1639_RS26090"
                     /old_locus_tag="EC1639_05139"
     CDS             12276..12710
                     /locus_tag="EC1639_RS26090"
                     /old_locus_tag="EC1639_05139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001547186.1"
                     /translation="MMNKFSYVNRMLRQVFVFSFITAPSISLFVVFMFFSFNNSIAGSF
                     LKEARGLITDTPSDKVNVCLFEKGVPQDMELTNSTTEHVLKNKCITTLVDAADWQESVD
                     GSIRYFYWSSVVIGFVVWFTFNFCALEELFYRRKRKGDVE"
                     /name="hypothetical protein"
     gene            12707..13240
                     /locus_tag="EC1639_RS25385"
                     /old_locus_tag="EC1639_05140"
     CDS             12707..13240
                     /locus_tag="EC1639_RS25385"
                     /old_locus_tag="EC1639_05140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001547187.1"
                     /translation="MRIFLSVILFLFTAFQSANAGGIPGALAGILSTLNLEIQGKVIRV
                     LDGDTIEIKTLPAKIVVYEVPIRVRLINIDAPEKKQPFGRWSTSQLKTLVAGKQVTVSY
                     SHKDRYGRIIGHVFTTNGTDASRFMVQSGAAWVYERYNVDESLPALQREAQEQKRGLWA
                     DANPVPPWEWRHEY"
                     /name="thermonuclease family protein"
     gene            13251..13592
                     /locus_tag="EC1639_RS25390"
                     /old_locus_tag="EC1639_05141"
     CDS             13251..13592
                     /locus_tag="EC1639_RS25390"
                     /old_locus_tag="EC1639_05141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001547188.1"
                     /translation="MNDCFGCMHPYPAGHWFYSLQDFTPLLENPLFYVFFFFFAGMAGV
                     IISRITNLIKSMRHDNKPSIDNYEQIEIERYMTNEEVGRLVINFMKRTNGEPLLIVFPE
                     YDNGDENRN"
                     /name="hypothetical protein"
     gene            13713..14975
                     /locus_tag="EC1639_RS25395"
                     /old_locus_tag="EC1639_05142"
     CDS             13713..14975
                     /locus_tag="EC1639_RS25395"
                     /old_locus_tag="EC1639_05142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_001547189.1"
                     /translation="MGKLSLVEQALLLHKEYYGEGDFGTVVKDYDYYPKVAEIFINRKN
                     RKIYSNLDIEPVASTVVHTGSSPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIRFI
                     LNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKLGYYDGVYYHGKARKEE
                     IENAMRFSVHPKFDELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIAKALG
                     AKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGADTPRN
                     VAGTYVIFSTNYPKRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPEDVEIDLKE
                     LGAVLDRTTPAEIKEIINIAIGMIRGTKNELSVDVIKNARAFLKGTLDLSVQEADEDIE
                     EREELYKQNGAQPDYLSYLED"
                     /name="AAA family ATPase"
     gene            14979..17129
                     /locus_tag="EC1639_RS25400"
                     /old_locus_tag="EC1639_05143"
     CDS             14979..17129
                     /locus_tag="EC1639_RS25400"
                     /old_locus_tag="EC1639_05143"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_109537469.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPDYKAWKVETLPLRLYPVKYQPVESAAKQVNTILELIRRGDVTEIVHAGD
                     PDEEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAQARGYKGTLSVGRVQTPILGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFDQPMNVDTTRKSKAFDSAKVTAHTAIIPTANVPDINALTPDERNVYLAIAQ
                     HYLVQFMPEKLYKEVSVAIQCGDESFYARARKTTDSGFETFLGTETTNEDESDNDDSAF
                     EQLCKIRTGETLTTKEVVVNEKKTTPPPLFTEASLLAALVRVADFVTDPVIKKLLKDKD
                     KDKKDEHGGIGTPATRAAMLEALKKRNYITLEKGKLIPTDTGYALIDALPDIAVNPDMT
                     ALWAEKQTAIENGDLTVEEFINELYDELTGMISDVDLGEMKIEPVAPAGQSQRLSSPCP
                     TCGKQIIIRQKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGTY
                     DTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            17126..17332
                     /gene="hha"
                     /locus_tag="EC1639_RS25405"
     CDS             17126..17332
                     /gene="hha"
                     /locus_tag="EC1639_RS25405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            17350..17814
                     /locus_tag="EC1639_RS25410"
                     /old_locus_tag="EC1639_05144"
     CDS             17350..17814
                     /locus_tag="EC1639_RS25410"
                     /old_locus_tag="EC1639_05144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293140.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREVDFEQLLEMQEKLNVV
                     VEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIDKLQPGQVE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            17918..18574
                     /locus_tag="EC1639_RS25415"
                     /old_locus_tag="EC1639_05145"
     CDS             17918..18574
                     /locus_tag="EC1639_RS25415"
                     /old_locus_tag="EC1639_05145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001478769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001478769.1"
                     /translation="MMIKSKKVVVIFVALSSFLLAGCDSPKDANKQNFEKAINTRLEKE
                     CITISPLGMFDSKPYPVQVAVAQANRYTSQERADEINSRQFSALDVLVKADLLTVKDTL
                     VDDVIGFTKTGKKVPGREYALTDEGKKYLKSPERPDFCVGHYKVDEIVDFTEPGDAMGM
                     KITQVNYTFSPTSIAEWAKRDDVRAAFLGLESDLKEKQTKRITLVLKNDGWSAER"
                     /name="hypothetical protein"
     gene            19130..19954
                     /locus_tag="EC1639_RS25425"
                     /old_locus_tag="EC1639_05146"
     CDS             19130..19954
                     /locus_tag="EC1639_RS25425"
                     /old_locus_tag="EC1639_05146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487124.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_197731664.1"
                     /translation="MSHLPASIFQISRSDAWNLTLSPDAARNMRDLAAQIGAGMPKYLI
                     APEVSLLLSYIDDLNIRMYFETLWNTGARLNEALALKPADFMLTPTRQYPQPVVILKTL
                     KQRLKEAERRPGRPTTRHPPLHPDPRYRKPPEPAVRLVPVLDAGYALRMREYLATWKKR
                     IKHQPVWDITSRQTPLNWINTAVARAERDGVTFSVPVTPHTFRHSYAMHLTMSGVPPRV
                     LQSLLGHRYARSTEIYTRVFSLDVLTGSGLSFTCDPQRAKQLLGYPECINDE"
                     /name="tyrosine-type recombinase/integrase"
     gene            20059..20718
                     /locus_tag="EC1639_RS25430"
                     /old_locus_tag="EC1639_05147"
     CDS             20059..20718
                     /locus_tag="EC1639_RS25430"
                     /old_locus_tag="EC1639_05147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-arginine deiminase"
                     /protein_id="WP_000516221.1"
                     /translation="MGKIITVAGHKGGIGKSTVLCSLCVCAIRKGKTACFLETDSQGSI
                     KDFIEERKTNDRLSEIPYFECYTDIPAMARKLAARFDYVFVDTPGMKSPAFVKALSCAD
                     ILFTFIEPGAGIEINTLGRLVFDIKTAQAGVNPSMKAWIVLNKCSTNPSDSEASELRRQ
                     LNDDPDWLPVPRQRIYMRTAHKKAYNSGMGVHEYDDKRGNKARGEIELLLKETGVL"
                     /name="peptidyl-arginine deiminase"
     gene            20811..21113
                     /locus_tag="EC1639_RS25435"
                     /old_locus_tag="EC1639_05148"
     CDS             20811..21113
                     /locus_tag="EC1639_RS25435"
                     /old_locus_tag="EC1639_05148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001096509.1"
                     /translation="MAKLPKKIDQEIKPLDLRQFVSSAAQKPASASAVTRINLTMTNDD
                     LDTAQVFQNEYGASRAEVIRAALAALRLVSAEERRRLFDDIRKNSPKAGRPTVNK"
                     /name="hypothetical protein"
     gene            21150..21434
                     /locus_tag="EC1639_RS25440"
                     /old_locus_tag="EC1639_05149"
     CDS             21150..21434
                     /locus_tag="EC1639_RS25440"
                     /old_locus_tag="EC1639_05149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_109537467.1"
                     /translation="MLIKIIKSVFNFYMLCVQPLLGLFLVGYSIWSFSGDGICTADKVI
                     ACDISIYLEPAFYLLIGSVVLFVWYIAWQTERSKEEDFKSSIKPEDFVK"
                     /name="hypothetical protein"
     Typing          965..3114
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.721"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4125..5254
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.939"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5503..6212
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.578"
                     /coverage="100.0"
                     /evalue="4.8e-137"
     Typing          6221..7146
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.706"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9388..11183
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.164"
                     /coverage="98.0"
                     /evalue="0.0"
ORIGIN
        1 ctcaatacgc catacgtggc actgtatcga atgaaaagga aacaaaagat gtcgaaatta
       61 aatctgaata aacgttattt aacgctttct ctatttatgg ctgcgttgat gctttgtgtt
      121 gcagaacctg cttttgcgga tgatgtgtct acgaagacaa ctggtttttt acagaaaata
      181 attgattttt taacggatgt tcgtaaaccg gcaattacaa ttatggctct tgttattgga
      241 tatattgcat tattttcgcg tcaacatacc gcatggatag tcccactcgt tatcggaatt
      301 atcatcttta ttgttgcacc atatattcct aactggcttg cgtaattaaa ggatgggcgc
      361 actatgagta ctctttttaa aggtcttacg cgccctgctt taataagggg gctgggcgtt
      421 ccgctctacc cctttcttgg aatgtgcatt atttgtgttc tgcttggtgt ctggattcat
      481 gaggctatgt acgccctcat tcttcctggc tggtatgcca tcaggcgtgt aacacagttt
      541 gatgaacgct tttttgacct tctgtatctg agaacccttg tcaaagggca tcctttatca
      601 aacaagcgat tcagcgcagt ccattatgcg gggagccagt acgacgaagt tgatatttca
      661 aaagtggata actttatgaa gctgaaagac cagtcttctg ttgaagagtt aattccgtac
      721 tcttcacata tcactgacaa cattatcgtt acaaaaaacc gggatttgct ggcaacctgg
      781 cagatagacg gtgcttactt tgagtgtgtt gattctgaag atttgtcaat tctgacagat
      841 cagctcaata cgcttatacg tagctttgaa gggaaatctg ttacgctgta tcctcatcgt
      901 atcagatgta aaaaggacgt cagaccagta tttaacagta aaattccttt tgtgaacaga
      961 gtaatgaatg attattacga gtcattccct cagtctgaat ttttcgagaa taaattattt
     1021 ctgacgattt gttttaaacc ttttactacg gaagataaag taacgcattt cttttcacgc
     1081 ggtaaaaaac aaaaagatat ctttaaagag cctgttaatg aaatgaatga aatttgcgac
     1141 aggttgaaca cctatctgtc ccgttttcat tcccgacgtc ttgggcttta tgaagatcat
     1201 ggggttgttt attcagatca gttatctctg ttccagtatc tgctttctgg tcgatggcaa
     1261 aaggtcaggg ttagcagtag tccgttttat acatatctgg gaggaaaaga cctgttcttt
     1321 ggtaatgatg ccggacaaat taccgcgtca gaccatgccc ggtattttcg ttgcatagag
     1381 attaaggatt attttcagga gacggatgcc ggtattctgg atgctctgat gtatctcccc
     1441 gttgagtatg tcgtgacatc gtcctttact gcgatggata agcagtcagc gattaaggcg
     1501 ctggatgatc agatcgataa gctggaaatg acggatgatg ctgccaaatc tttgctggca
     1561 gatctgaaag tcggactgga tatggtttcc agcggatata tttctttcgg gaaatcgcat
     1621 cagaccctgg ttgtctttgc ggattcaccg gagcgtctgg tgaaagacac caatatcgtg
     1681 acttccactc tggaagattt ggggctgatt gtcacttatt caacactgag tcttggcgca
     1741 gcttattttg ctcagcttcc aggaaattat acgcttcgcc ctcgtctgag taccctcagt
     1801 agtcttaatt ttgctgaaat ggaaagtttt cataatttct tttcaggaaa agaaaaagga
     1861 aatacctggg gggaaaaact gattactctt cgggggtcag gtaatgatat ctaccatctg
     1921 aattaccata tgacgactga acatcagaat ttcttcggta agaacccgac gctggggcat
     1981 accgaaattc tcggtacgtc taacgtgggt aaaaccgtat tactgatgac aaaagcattt
     2041 gccgcccagc agttcggtac gccggaatca ttccctgcaa acagaaaact gaaaaaactg
     2101 accacggttt ttttcgataa agaccgggca ggtgaagtcg gtatacgggc tatgggggga
     2161 tcttattacc gggtgaagga gggagagccg acaggctgga atcccgccgc actgccgcca
     2221 acaaaacgta atatcgcttt tatgaaggac ctggtgaggc tgctttgtac tctcaacagt
     2281 gagccgctcg atgattacca gaacagcctg atttcagatg cggttgaacg tcttatgcaa
     2341 cggtcagatc gctcttatcc tatcagtaaa ctacggcctc ttatccagga gccggatgat
     2401 actgaaacca aacgtcatgg acttaaagcc cgtcttaagc cgtggacgca gggggaagag
     2461 tttggctggg tgttcgacaa tcgggaagac acgtttgatg tcgataacct ggatgttttc
     2521 ggtattgatg gaacggagtt cctggataat aaggtgctgg ccagtgctgc ttcattctat
     2581 ctcatctatc gggtcaccat gctggccgat ggtcgcaggc ttcttatcta catggatgag
     2641 ttctggcaat ggatcaataa cgaagcgttc agggactttg tttacaacaa actgaaaacc
     2701 ggacgcaaac tcgatatggt gcttgtcgta gccacacagt caccggatga actgattaaa
     2761 tcacccattg tggcagcggt tcgtgagcaa tgcgccactc atatctatct ggcaaacccg
     2821 aaagccaaac gtagtgaata tgttgatggt ttgcaggtca gggagcttta ttttgacaaa
     2881 attaaagcta ttgatccgct gtcccgccag ttcctggttg ttaagaaccc acagaggaaa
     2941 ggtgaaagtg atgattttgc tgcttttgcc agactggagc tgggaaaagc agcgtattac
     3001 ttaccggttc tcagtgcatc aaaaccccag ttagaactgt tcgatgaaat ctggaaagaa
     3061 ggaatgaagc cggaagagtg gcttgatacc tatctggaac aggcgaacct gatttgagga
     3121 atcaccaatg aaaaagcaaa ttatggcggc attcgtcgct tcactgattg ttatttccgg
     3181 cgctcaggca gggatacctg ttgccatcga cgccaaccct gaatgggcga ttgaagccgg
     3241 acgatggaca gaacgcctta agcaatgggc ggaaacggta aaacattacg aaaatcagat
     3301 aaatgcgtac aaacaggagc tgctgtcaaa aacgggtatc cgtgatgtgc agggactggt
     3361 gcagtccgca cagtcagtga gtcaggaact gatgcagatt tatgatcagg ggaatgcttt
     3421 tattgacgat tacattaaaa atcctgaagg ggcgttatcg gaacaggcca aatcgttatt
     3481 gtcggattac aaagtaacgg atacctgcca gaacctggga tattccggcg acctggtacg
     3541 gggatgtgaa gcgacgttcc tttctcaact ggcaagcgtg gaatacggta acaagctgga
     3601 gagcaagctt cgtcaggaca accagacgat gaaagacctt attgatcaag tcaaaaatgc
     3661 gaaggatacg aaggccacgc aggatgcaac aaacgctgtt gcacttgaac aactgaagtt
     3721 cgagaagctc aaatttcagt atcaaatgta tcgcgataag cagcgagatc ttgcagaata
     3781 taaagagaag atggctcagg cttctttcag aaaacagcaa cgtgaagccg tgcctccttc
     3841 ttacagaaaa gcttatatgg caatgaaatc atatgaggat gattaaatga aaagtatcgc
     3901 tactgctggc cttgtcatta tatctgtttt tagtctttct ggatgttttg aagaaacaaa
     3961 atcggttgat tggtggcttg cacatccgaa ggagacatac aaaaaatttg aagagtgtca
     4021 gaagtctggt agcgattctg ataattgtaa gaacgttaag cgagcacatt tgtcttttga
     4081 acggagaaag gcggttggtt taccaataaa ttgagggtga tgtatgggga ttgtcactgg
     4141 tataccggat ggtactgatt tatcaggtaa tgtaacctct cccgcaaatg cgggaggtgt
     4201 tcctgggttt gattctgatt tttttcagac aactcatgaa gttatattta acattctcaa
     4261 taagagtata tctggaaaat taagtgaata ttcagatgtg gcttatactc ttggtaaata
     4321 tggagtttct ctgtatgttt tatggtatgc ctttactgta ttagcaagga aacaacagac
     4381 acctgtacct gattttatct ggaatatctg taggttttac ataatattgc tttttgttaa
     4441 gaatacaggg ggaatactta catcagcaac agatgctatt gatggattga aaaatacatt
     4501 ggcaggggga gatccgtggg tatggatgga tcagttatgg gtgaaggtta tacaagttgc
     4561 aactcttatt tttgataaag atacatctac tgtgcctgtt gccggtggga ttggtgcttt
     4621 attaacttat gttggtggtg ttttggcatt attgctttgt tctatagtat ttgcagctgc
     4681 tgaattaaca ttactattac tttctgtcac tgcgccaata tttatcatgt gtttgatgtt
     4741 tggtttcctt cggcaaatgt ttaatagctg gctacagctt aattttagct cgttactggt
     4801 ttttctattt gcagcattag cactaagagc tgggacatgg caattaaaca tggcattaag
     4861 tacgtctatt gctacagcat cagaaaacaa tcttcttcaa acgggagtaa cttcattagc
     4921 tgctggcatt ttcatggcct ggattatctg gcaggcgaaa agttatgctt cacagattgc
     4981 aggtgtgggt gttgaaggtg ccatgcaggg cgcagccgct atggggattg gtgctggcgt
     5041 tttcggtgca tcccgtatgg cgcgtggcgc acttggtatg ggcagaaatg ccggtattgg
     5101 tgcatggaaa ggtctgcgtc gtcaggaagg cgggtttggt cagtctccgg gaataacggg
     5161 taagaccgct aacctggccg gacagggcgt taatattggt gccaaaaagc ttcgtcaggc
     5221 agctattgag agggcaaaga aaatgtatgg agggtgattt aattatgagt gttgatacca
     5281 ttttaaatgt tcttttcata attaacgggc ttgtcgcgat ctattttctt tgttcagact
     5341 gagtcttctg taaatattaa tctgttatac aggtgttcat attatgaaac tacttattgt
     5401 ggctttcgtg acgctttgtc tcgctggttg tcaggcgtca cataaactac cgcccgtttc
     5461 cgggaaaagc gaacctgtta attctgctga ggtaatgcaa aatggaattt aaacttcccg
     5521 gatttaaaaa taaaaaagac gttactgact catcagtttc gtttgaagaa aaaaacattg
     5581 cactacagga gagaatgaat cgtatttata aattcggtgg tatcggaggc atgttaattg
     5641 gtgggctgtc tttacttgca ttaaatgcag cattaccact gaaaacaaca gttgttgatg
     5701 cctaccttat cgataaggtt acaggtgtgg ctgaacgtct gacttctgtt aaaaaagaaa
     5761 atctttctga aaacgaagcc attgcccgat attttatcac ccagtatata aaacatcgtg
     5821 aaggttataa ttttttcagt ctccagcatg attatgatta tgtaatggct tacagcgcgg
     5881 agaatgtcgc ggcagattat aacgcattat ttaacagtga acaggcacca aaacttgttt
     5941 ataacaaagc agaaaaaacg gcaatggttc aggataatcc atctgtcata atttcacctt
     6001 cgtcacggac ggatgataaa gatatcggtg cgtatattcg ttttcgtctg accatcaggg
     6061 atgttgctac cggacaaacc cgccaggagt tctggaatgt tcgcctgact tatcgtatcg
     6121 aaccgcaggt tgaaatggtg tcaggggaac gtaataacaa tcctcttaag ttcgttgtaa
     6181 caagctacgt tcgcgataaa gaagccagag gttaataata tgaaaatgaa taaaggagcg
     6241 ttaattatgg cgcttctgat ggcggcgcac gtctgtaatg ctgctgttct tccttcaggc
     6301 agtcgctttg acccacgcaa tcagatagtc agttataacc ccaataatac caccataatt
     6361 aacagtgccg ttggatacac caccacactg gtatttgatg aagatgaaac agttatcagt
     6421 gccagaactg gttttccgca gggatgggcg gttaataaag aagataacct ggtatatctg
     6481 gaagttcgtc ctgttaaaca gactgttcag aaaaataata cggatgaaaa cggtaatacc
     6541 tcttctgaat ccgtcagtgt tgctcttgac ccggaaaatg agcttgaacg ctggcgaacg
     6601 aatctgtttg ttcgtaccac gaaacgtaat tacagcatgg agctgaacgc cagaacgttc
     6661 cgacagccgg agaaaattgc gtttgtggtg aattaccagt atccgcagga acgccggaaa
     6721 gaacaggccg aaattgagaa gaaacgcaca gagactcttg ccagacgcct ggaggaacag
     6781 gcaatcaacc gttccctgga aaatgcgaaa tcgccccgta actggcagta ctggaagcgg
     6841 gttgctgaag gcagccagga tatcagccct gattatgcat atgacgatgg tcgttatacc
     6901 tggttcggct tcagtccgtt aaagaaaatt cccagcgtct ttgtgatgaa cggtatgcag
     6961 gagactctta ccaatcctgt gattaaacag agcggaagtt ttacggctgt tggcgtaccg
     7021 gttgataagc gttttgtttt acgtcttggt gagcaggtgg tggggattga gaaccagggc
     7081 ttcggaaaag tacgtttacc agccggagat acggtatccc cggatgttaa gaaagaggtg
     7141 atccagtgac tgaacaggaa aataaaatcc cgactgcaac cgaaattgaa cagcagttac
     7201 gggaacgcag acagaaagaa ctggaacagg ccgggaagac cccggaagaa gagcctggca
     7261 agccagcatt gcagcttggt attgaaaaac ttaaaaaatc acgtaaaggg atgattatcc
     7321 tcgtcgtggg ttttcttctg cttgctgccg gtgtttctgt ttattatatc ccgtccatta
     7381 tccgttctgt gtcgtcaggg gatgagaaac ccgcaagtca gccgcttgca accggagagg
     7441 ctaaacgtca gaccggactg agcgaagata tcgatccttt taataccgca cagaaaaaaa
     7501 cagagaaacc agaggaagaa aaagtcattt cttctgaaaa gactgaaccg ccggaaaata
     7561 aacagcagag cttcagccgt gcacttgacg tttctcttga tggcagccag gcaggaaaca
     7621 gcagcagttc agcgggaacg tcagtttcac atactgcggc cagtgagcca gaaagcgata
     7681 aaaaggatga agcaaaagca accgcacagg ctacggaatc tgcgccactg gcgaaaataa
     7741 cgaaacttcc atatgaccca aatttgttta tcccggaagg gagatcaatt ccctgttcac
     7801 tggacaggcg ttttgtttct gacctggcgg ggaaactgga atgtacggtc aacagtgata
     7861 tatacagcgc cagtggcaat gtaaaactta tcgaaagagg aaccgccgca aaactgatgt
     7921 ataaggccgg gtctttaaat catggacaag ggcgtgtgtt tgttatggct tataagctac
     7981 gtacccgcag taagcctttt attgatattc ccctggttga ctcacaggcg gctggcgcgt
     8041 taggcgaagc cggtgcttct ggctggattg acactcattt cagtgaacgt tttcttggtg
     8101 caatgatggt cgggatgata ccggatttaa gtcaggcggc cagtggtatt gctcagaata
     8161 acagggacag tcagacggac tatacagcta acagccgcca ggcttttgct gatatagcac
     8221 gcgaagcatt ttctaatagt gtgaatatcc cgccaacgct ttataaaaat cagggagaaa
     8281 ttattactct gattgtcggt caggatctgg atttttcagg tatttataaa ctgaaaatga
     8341 aagggggtta atgtgaataa cgaaaacaga catctgattt atgatgtggt taacgactat
     8401 ttttatcact ggctgaatga gactgatggt gtcacggaaa tcgctgttaa ccgaccagga
     8461 gaaatattta taaaggtcag gggaaagtgg caatggtatg aacaaaagat gagttacagt
     8521 gattgtcttt cttttgcatc cacactggcc gattttcatg acggcggttc tgtgactcct
     8581 gaatatcccc tgcgttctgc cacgcttccg ggtggagaac gtgttcaggt tgtgatccca
     8641 ccggcaactg aaaaagatac tgtttctata acaatccgta agccgtcagg tatttttatc
     8701 agtcatgaca aatttataaa acagggattt tattcacgcg tcagtggttt aagtggtgac
     8761 tctgttatgg aagataatat ttctgcttta atcacttccg gatattttga acgggttata
     8821 cctgaatcac tgagtcaggg gaaaacgata gttttctgtg gaggaacagg gtcaggtaaa
     8881 accacctttg caaatgcctg tctggaatat ataccgcatc atctgcggtg tatttctatt
     8941 gaagatactg atgaggcaaa attcagattt cataaaaacc atgtaaaact ttactatccg
     9001 gcagaggggg agagtaagat tattacctca gcgagtcttc tgcgttcctg ttttcgtatg
     9061 aatccggaca ggattctgat gacagaaatc aggggagctg aggcatggga ttttctgaaa
     9121 gcatcgagtt caggccatgc aggaaacatt accaccgttc acgaaagtag tcctgaatat
     9181 gccgtgcttg ggattgtcca gcgatgttat atgaatcctg aatgtcagaa tctaccattc
     9241 aatgtcattt taagacgtgt actgagtaat attgatatta tcatgagtat taaatacctt
     9301 gatgatgaag attttcggtt cgcttccggc atttactaca gacaacttca ttttgatgat
     9361 tatttcagaa aactgaagga gtgattatgt ctttaaaact ccccgataaa ggccagtggg
     9421 tttttatcgg tctggttatg tgtctcgtga cctattatgc tggttctgtt gctgtttatt
     9481 tcctgaacgg aaaaacacca ctgtatatat ggaaaaattt tgattccatg ttgctctgga
     9541 aaataataac agagagtaat atacgtacag atatcagact gactgccata ccttctcttt
     9601 tgtcaggtat ggtttcgtct ctcattgtgc ctgtttttgt tatctggcaa ctgaataaaa
     9661 tggatgttgc tctttatggt gatgcgaagt ttgccagtga caatgattta aaaaaatcaa
     9721 aactgcttaa gtgggagaca gaaaatgata cggatattct ggtcggcgcg tataaaggaa
     9781 aatatctgtg gtataccgcc ccggattttg tatctcttgg tgcaggaacc cgcgccggta
     9841 aaggtgccgc cattggtatc cctaatcttc tggtcagaaa acactctctg attgcgttag
     9901 atccaaaaca ggaattgtgg aaaatcacca gtaaggtgcg tgaaatactg ctgggtaata
     9961 aagtttatct tctcgaccca ttcaacagta agacacatca gtttaacccc cttttctata
    10021 ttgatttaaa agcagagagt ggtgctaagg atctgcttaa actgattgaa attctgtttc
    10081 cgtcttacgg catgacaggg gcagaagcgc actttaataa ccttgctggt cagtactgga
    10141 caggactggc taagttgctt catttcttta ttaactatga gccgtcctgg cttaatgagt
    10201 tcgggcttaa acccgttttc tcaatcggtt ctgtcgtcga cctgtacagc aatattgaca
    10261 gggaactgat actcagtaag cgggaagaac tggagggaac aaacggactt gatgaaaacg
    10321 cgttgtatca tttgcgcgat gccctgacca aaatcaggga atatcacgaa acggaagatg
    10381 aacagcgttc aagcattgat ggttctttcc gtaagaaaat gagcctgttt tatctcccaa
    10441 ccgttcgtaa atgtactgat ggtaatgatt tcgatctccg tcagttgcga cgggaagata
    10501 tcactgttta tgtcggtgtt aatgcggaag atatatctct ggcttacgat tttctgaacc
    10561 tgtttttcaa cttcgttgtt gaagtgacat tgcgtgaaaa tcctgatttt gatcccaccc
    10621 tgaaacatga ctgcctgatg tttcttgatg agttcccttc gattggttat atgccaatta
    10681 ttaaaaaggg gtcagggtat attgcaggtt ttaaacttaa actgctgacg atttatcaga
    10741 atatcagtca gctaaatgaa atctatggta ttgagggagc caaaacgctg atgagtgctc
    10801 atccatgccg tattatctat gctgtcagcg aagaggatga tgccgcgaag atatcagaaa
    10861 aacttgggta tattacaacc acatcaaaga gcacaagcaa gagccgggga cgatcagctt
    10921 cacagggcga atcagaaagt gaagcccgaa gagcactggt gcttccacag gagctgggaa
    10981 cgctggactt taaagaagaa tttatcatcc tgaaggggga gaaccctgtt aaagcagaaa
    11041 aggcacttta ttaccttgat ccgtatttta tggacaggtt aatgaaggtc agtcctaaac
    11101 tggcatcatt gacgatggaa ctaaataaga cgaaaaaaat atttggtgtg aaagggctta
    11161 aatatccgtc aaaagaaaaa atgctctccg taggagagct ggagtctgag gttttgctat
    11221 gaaaaaaata cttatgatca gtattcttgt cctcacagcc tgttcctctc cacctgaacc
    11281 gccacaggtt gaatgggaaa aaatgcctga agttatgaat acacaaataa tgaactggac
    11341 accaacatct aacgttatta aatcagataa tataaattcc ttatggagta aggtgttgcc
    11401 tgattttaaa ccagaaaatc gtctttacga tgattctgtt ttttatgcag ttgcccactc
    11461 tgaaaaaata gttgtaagga catcttcttt tgatagttac tggtcagcga aagactggct
    11521 aagaaaaaat ggtgcaacag gtgttattga atatcatcca ctaaaaagat ggttgaataa
    11581 tgactatgtt gaaatttatc tgtcaagaat aaatgttcag aggttaccat gaaaaagata
    11641 tgcaaaggtc taatcgtaat ttttactgtg tcctgtttta tagcgccaac gtatgccgct
    11701 gatccctgta aatccgtttt ttgtctttat ggtaaagctg tcggtagtag tggagggagt
    11761 gagtgcagca gtgcagaaaa ggattttttt aaaaatgttg aaaagaaaaa ggggaaaatc
    11821 cgctggggta aaacatttga tctccgtaag aattttttaa atcagtgttc aacggcagac
    11881 ccggctgcaa tctcactgat catgagtaag tttggtaaga ttaaggggta gatgatatga
    11941 aaaaaaaaga aaagattgat tttcttaatg caataaaagc agggcactct ggctttatag
    12001 ctggtaatcc tgctcatgca ttggatgata agactatgaa tgccatcatt cataactacg
    12061 aggcaacgat tgcgcccggt aaagcaggta actgcaaaga aactcctctc acaaagtatt
    12121 gttcgaggac tatgccagag cgtatttcag ttgaagaaat taatgaggtt aaaatttatc
    12181 cagaattctt ctgaacagag ataaatgtaa acgccgcaga ttccagattt taatctggaa
    12241 tttgcggggt tgaacaaccg aagggcgtta gttttatgat gaataaattt agttatgtca
    12301 atcgtatgct tcggcaagtt tttgttttta gttttatcac ggccccatca atatctttat
    12361 ttgttgtttt tatgtttttt tcgtttaata actcaattgc tggttcattt ttaaaagagg
    12421 ctagggggct tataaccgat actccttctg ataaggttaa cgtctgtctt ttcgaaaagg
    12481 gcgtaccaca ggatatggag ttgacaaact ccacaactga acatgtatta aaaaataaat
    12541 gtataacaac gttagttgat gctgctgact ggcaggaatc tgttgacggt tctattcgat
    12601 atttttattg gtcgtcagtt gttattggct ttgtggtctg gtttaccttt aatttttgtg
    12661 cactggaaga actattttat cgtagaaaga gaaaaggaga cgttgaatga ggattttttt
    12721 aagcgtgatt ttattcctgt ttactgcttt tcagtctgca aatgcaggtg gaatacctgg
    12781 tgctttagca ggaatacttt ctacattaaa cctggaaatc caggggaaag ttattcgtgt
    12841 tctcgatggc gacactatag aaattaaaac actacccgca aaaattgttg tgtatgaagt
    12901 tccgatccga gtccgattga taaacatcga tgcccctgaa aagaaacaac cttttggacg
    12961 ctggtcaact agtcagctta aaactctggt tgcaggtaaa caggtgacag tctcttattc
    13021 acataaagac cgctacggac gcattatcgg tcatgtgttc acgacgaacg gcacggatgc
    13081 cagccgcttt atggttcagt ctggcgctgc atgggtatat gaacgttaca acgtggatga
    13141 gtcattaccg gctctacaac gggaagctca ggaacaaaaa cgcggtttgt gggccgatgc
    13201 aaatccggtt ccaccgtggg aatggcgaca tgagtattaa ggagacaaaa atgaatgatt
    13261 gtttcggttg tatgcatcca tatccggctg gtcactggtt ttattcttta caggatttta
    13321 caccactact tgaaaatcct cttttctacg tctttttctt ttttttcgcg ggtatggcag
    13381 gtgtaattat atcaagaata actaatttaa ttaagtcgat gagacatgac aataaaccat
    13441 caatagataa ttatgagcaa atagaaatag aacgctatat gacaaatgag gaggtaggca
    13501 gactcgttat caattttatg aaacgcacca atggtgaacc gttgctgatt gtttttcctg
    13561 aatatgataa tggagacgag aacagaaatt gagacagtta ataattataa caagattgaa
    13621 atatcagtca taaactgaac agacgaatct gactttttct gaccttcggt tacctgaagt
    13681 aatctcaagg ttttaatata caggatgtgc atatggggaa attatctctt gtagaacagg
    13741 cgttactcct ccataaagaa tattatggtg aaggtgattt tggcactgtt gtaaaggatt
    13801 atgattatta tcctaaagtt gctgagattt ttataaatag aaaaaaccgt aaaatttact
    13861 ccaatctgga tattgaacct gttgcctcaa ctgttgttca tacgggaagt agtccagtga
    13921 tggctaaagc aggacgaatt aaaaaactta tgtttaaaga tggttctggt gcatacagga
    13981 ttcatcttgg tcaaaatgaa gtggttcata ttattcgctt tattcttaac tctaaagtca
    14041 ggatggagta cgccgttggt actactaaaa gtatgtcaat gctccataat ctttgcgagg
    14101 caggacgggc taaattaaac cgttccttac cacgtaaagg tatctggaaa cttgggtatt
    14161 atgatggggt ttattatcac ggaaaggcaa gaaaagaaga gattgaaaat gctatgcgtt
    14221 tctcagttca tccaaaattt gacgagctgg aaaacgactt taatcagttc ttttctgata
    14281 ttgatttcta tacccggtat ggtcagtcag gtatgcgtaa agtgctcttt actggccccc
    14341 caggaacagg caagacaact atcgcaaaag ctttgggggc aaagtatcag gataagtatg
    14401 tttttgttta tgccgacgat tacttcaaag atgtttgtta cgccgctgct cagaagaaaa
    14461 tacccgtcat tattatagcc gaagaggttg atgagcttta tcgggctgat gccggaacgc
    14521 taagttttct cgatggagct gatactccgc gaaatgttgc cggaacatat gtgatttttt
    14581 caacaaacta tcctaagcgt attgacccac gcattagaaa acgtcctggt aggattgaca
    14641 ggataatctc tgttggtgct ttcagaacta aagccgctgc cgcttgcgcc aaaatgtact
    14701 taccagaaga tgtagaaatt gatcttaaag agcttggcgc agtgctggac agaactaccc
    14761 ctgctgaaat taaagaaata attaatatcg caatcggaat gattcgagga accaaaaatg
    14821 aattatcagt tgatgtaata aaaaatgctc gtgccttttt gaaaggaacc cttgatctga
    14881 gtgtgcagga agcagatgaa gatatagaag aaagggaaga gctttataaa cagaatgggg
    14941 cgcaacctga ctatttaagt tacctggagg attaaataat gagattattt atcgcagaga
    15001 aacccgcagt agcaaatgat attgttaagg cattaggtgg aaattttaca cgtcatgatg
    15061 gctggtttga aagtgataat gccattgtga ctaactgctt tggtcatatt atcgaatcac
    15121 agccaccgga aaactataat cctgattaca aagcctggaa agttgaaaca ctccctttac
    15181 gtctttaccc cgtcaaatat cagccagtag aaagtgccgc aaagcaggtt aacacaattc
    15241 ttgagcttat cagacgtgga gacgtgactg aaattgttca tgctggcgac cctgatgaag
    15301 aaggtcagct acttgttgat gaagttctgg aatatgcggg gaacacaaaa cccgttaagc
    15361 gcgttctgat taacgacaac acgcttccgg cagtgaaaaa ggcactggca aatcttaaag
    15421 ataatcgtga tttcaaaggg ctttacctta aggcgctggc gcgttcagtt gctgatgccg
    15481 tctatggctt ctctatgacg cgtgcttaca ccattccggc acaggccaga ggatacaaag
    15541 gtacactttc agtaggacgc gtccagaccc ccattcttgg cctgattgtg aatcgtaccc
    15601 gcgctaacca gaaccataaa tccagttttt actacaccat gaccggagtc tttcagcgtg
    15661 gtgctgatgt tatcagggcg aactggaagc caggggaatt tgctccgctg acagaccgta
    15721 aattacttga taaagcgtgg gcagacggaa cggcagcatc ccttgcagga aaaccggcta
    15781 cagttgaagc ggcagcaact gatgataaaa aaacggctgc gccgttgccg tttaacctgg
    15841 tcagactcca gcaatacatg aacaagaagt tcaaaatgac ggcacaaaaa acgctggata
    15901 ttacgcaaca actacgcgag aaatacaaag cgatcactta taaccgctct gattgttcat
    15961 atctttctga cgaacaattc agcgaagcgc cgcaggtcat cgatgccctg aaatcagttt
    16021 tcgatcagcc aatgaatgtt gatacaacac gtaaaagtaa ggcttttgac agcgcgaagg
    16081 tgacggcaca tactgcgata atcccgaccg ctaatgtgcc tgatatcaac gcactaacac
    16141 ccgacgaacg caatgtttac ctggcgattg cacaacacta tctcgttcag ttcatgccag
    16201 agaaattgta taaggaagtc tctgttgcca ttcagtgtgg cgatgagtcg ttttatgccc
    16261 gtgccagaaa aacaactgac agcggatttg agacatttct tggcacggaa accacaaacg
    16321 aggatgaatc agataatgat gattccgctt ttgaacagct ttgtaaaatt cgcactggtg
    16381 aaacactgac gacaaaagaa gtggttgtta atgagaagaa aacgacaccg ccgccattat
    16441 tcaccgaagc ctccttgctt gctgcgcttg ttcgtgtcgc tgatttcgtc actgatccag
    16501 tgatcaaaaa attactgaag gataaagata aagacaaaaa agatgaacat ggcggcattg
    16561 gtacgccagc tacccgcgcg gctatgcttg aagccctgaa aaaacggaac tatatcacgc
    16621 tcgaaaaagg caaacttatt cctactgata ccggatatgc gctaattgat gctctgccag
    16681 atatagctgt taatcctgat atgacagcat tatgggctga aaagcagaca gccattgaaa
    16741 atggcgacct gaccgttgaa gagttcatta atgaactata cgatgaactc acaggcatga
    16801 tttctgatgt tgacctgggc gagatgaaaa ttgaacccgt agcgccagca ggacaatctc
    16861 aacgcctgag ttctccctgc cctacatgcg gcaaacaaat tattatcagg caaaaaggtt
    16921 atttctgtac cggatgtgaa tttaaaatct ggagtgagtt ttctggtaag aaaatcaccc
    16981 aggcacaggc cgaaaaactg gttaaatcag ggaaaaccga tttgattaag ggatttaaaa
    17041 agaaaagtgg tggaacgtat gatacagttc ttgtccttga ggataagaaa acagggaagc
    17101 tgggttttcc ggcaagggct aagaagtgaa aacaaagcag gaatggcttt ttcagttaag
    17161 aaaatgtaca tcaagagata ctcttgaaaa agttattgag attaaccgtt acaaactgcc
    17221 tttatcagaa tcagaggcat tttattctgc cgcagatcat cgccgagcag aactggtgat
    17281 gaataaactt tatgataagg tgccttccgg cgtctggaag tacgtacact aaataagagg
    17341 attaattata tgagcgaact gactaaagaa gatgaatacg gcattatcag ccgtactatg
    17401 atgaatattc gttcattacg tgtttttgcc cgtgaagttg attttgagca attgctcgaa
    17461 atgcaggaaa aactgaacgt tgttgttgaa gaacgtcgtg aagatgctga acgtgaagcg
    17521 gctgaacgcc aggaacttga agccaaacgt cagcaggcca ttgaatacat catatcttta
    17581 ggtcttgatc ccgaatcact ccttgctcct gtaacagcag atacagtaaa aaccaggcgg
    17641 aaagccaaag gcggagtaag aaaggctaaa taccgcttta aggatgaaaa tggcgagatc
    17701 agagaatggt ctggtaatgg caagcgtccg cttgctttac agaagctgct tgatgagggc
    17761 catttcatgg aagatttcct cattgacaaa ctgcaacctg ggcaggttga ataaaataat
    17821 cgtgatgccg tcgcaaactt gtttgcgacg gcaaatggag gggacagaac agccagctgc
    17881 gctggcaaga aattttatcg tttgataaag agggaaaatg atgatcaaat caaaaaaagt
    17941 agtggttatt tttgttgctt tgagttcatt cttgctggca gggtgtgatt caccaaaaga
    18001 tgctaataag caaaactttg aaaaagctat taatactcga ctagagaagg aatgcattac
    18061 tattagtccg ctgggaatgt ttgatagtaa gccttatccg gttcaggtag ctgtggctca
    18121 ggctaatcga tatacatctc aggaacgggc agatgaaata aattctcgac agttttctgc
    18181 gctggatgta ctggtcaaag ccgatttatt aacagtaaaa gataccctgg ttgatgacgt
    18241 tattggtttt actaagacgg gtaagaaagt gccaggtcgt gaatatgctc tgacagatga
    18301 ggggaaaaaa tatctgaagt ctccggaacg gcctgatttt tgcgttggtc attataaggt
    18361 ggatgagata gttgatttta ccgaacctgg tgatgctatg ggaatgaaga tcacgcaggt
    18421 gaattacaca ttcagtccca ccagtatcgc tgaatgggcg aaacgcgatg atgttcgggc
    18481 tgcattttta ggacttgagt ctgatttgaa agagaaacaa acaaaacgta ttacactggt
    18541 tttgaaaaat gatggatggt ctgctgaacg gtaggctgta atggtgttgc tacgtgaaaa
    18601 ataccccacg tatatcccct actttttcac ggatttcacg tagcgcaccg ccgttaatga
    18661 ctctatcaaa aatactcacc gatatttttc gcaccgcaaa caacctaact cactgtaaaa
    18721 caacaaatca gctttgcgcc ggtgacgcat cgatcgcgct ggccagcgcg atcctcagct
    18781 gcgaccgcta cagtattttt gaacaagatt acccttgctc cggtttaatt cgccaggcag
    18841 ttagacatac aggtcattct gtccagattt cattagttac aacattcaca tgttccgttc
    18901 ctttatccgg tgccctgttc cggtctatgt gcccatatcc tgggttattc aggataaccg
    18961 cttccttttc gccctgccct gtcgttcata tccccctgga caaaaatgca ttatcggaaa
    19021 aaatgtccaa aaattttttt ggtgatcgga atttttgttg tcggacgcac ctctgcttca
    19081 ggtcataatt gctggcacgt ccaaaaaaac aggtgcggag attaaaaaat tgagtcattt
    19141 acccgccagc attttccaga tttcacgtag cgacgcctgg aatttaaccc tctctcccga
    19201 tgcagcccgt aatatgcggg atcttgcagc acagattggc gcaggaatgc cgaaatatct
    19261 gatagcaccg gaagtctcac tgcttctctc ctacatcgat gatctgaaca tccgtatgta
    19321 ttttgagacg ctctggaata ccggagcacg actgaacgaa gctctggcac tgaaacctgc
    19381 cgattttatg ctgactccga cgcggcagta cccgcaaccc gtggtgatcc tgaaaacact
    19441 caagcaacgt ctaaaagaag cagaaagaag accaggacgc ccgaccacca ggcatccacc
    19501 attacatcct gatccgcgat acagaaaacc accggagcca gctgtaaggc tggttcctgt
    19561 tctggatgcc ggatacgcat tgcgtatgcg ggaatacctg gcgacctgga aaaagcggat
    19621 caaacatcag cctgtgtggg acataacatc aagacagaca ccgctgaact ggatcaacac
    19681 cgcagtggca cgggcagagc gtgacggcgt aacattttcg gttccggtca cgcctcacac
    19741 gttccgccac agttacgcca tgcacctgac aatgagcggc gttcctccgc gcgtcctgca
    19801 atccctgctg ggacaccgtt atgcaagaag caccgagatt tacacccgcg ttttttcgct
    19861 ggacgtcctg acaggaagtg gcctgtcctt tacctgtgat ccacagcgtg caaaacagct
    19921 tctcggatac cctgaatgca ttaatgatga gtaataatac acaccattaa actattgcca
    19981 gcacgcaata gtacggttat actttcacca taaaagattg tgtattaata cacaccattt
    20041 aaccgggagg gttttgtgat gggaaaaatc attacagttg cagggcataa aggcggcata
    20101 ggcaaaagca ccgtgctttg ttccttatgt gtctgtgcca tcaggaaagg gaaaacagcc
    20161 tgtttcctgg aaacagactc gcagggaagc atcaaggatt tcatcgagga acgtaaaacc
    20221 aacgaccggt tgtctgaaat accgtatttc gagtgctaca cagatattcc ggcgatggca
    20281 cgaaaactgg ctgcccgctt tgattatgtg tttgttgata cgccaggaat gaaatctccg
    20341 gccttcgtta aggcactgag ttgtgctgac attctgttca cattcattga gccaggagca
    20401 ggcatcgaga tcaacacgct gggacggctg gttttcgaca ttaaaacagc acaggccgga
    20461 gtcaatccgt caatgaaagc atggattgtc ctgaataagt gttcaactaa cccgtcagac
    20521 agtgaagcgt cagaactgcg ccgacaactc aatgatgatc cggactggct tccggttccc
    20581 cgccagcgta tctatatgcg tactgcgcat aaaaaagcct ataacagtgg tatgggcgta
    20641 cacgaatacg atgataaacg gggaaacaaa gcccgtggag agattgaatt actgttaaaa
    20701 gaaacggggg ttctgtgatg tgtattatta cacactataa gagatgatat actcacatcc
    20761 tgaatagtgt gtataattac acactttaca agaacaggat acctaatcta atggcaaagc
    20821 tcccaaagaa aattgatcag gaaattaaac cgctggattt acgccagttt gtaagctctg
    20881 ctgcacaaaa accggcatcg gcatcagcag taacgcgtat aaatctgacc atgacaaatg
    20941 atgatctgga tacagcgcag gtgttccaga acgagtacgg cgccagccgt gctgaagtaa
    21001 tcagagcagc actggcagcg ttacgtctgg tatcagcaga agaacgccgg aggctgtttg
    21061 atgatataag gaaaaacagc ccgaaagcag gaagaccaac cgtgaataaa tagtgtgttt
    21121 tattacacac cattaaaggg gataaaaata tgctcataaa gatcattaaa tctgtattca
    21181 atttttacat gctctgtgtg cagcctttac ttggattatt tctcgtgggt tacagtatat
    21241 ggagcttttc aggtgacggt atctgtacag cagacaaagt tatagcctgt gatatatcaa
    21301 tatatctgga accagcattt taccttctca ttggcagtgt tgttttgttt gtatggtata
    21361 ttgcatggca gacagaacgc tcgaaagaag aagattttaa atcaagcatt aagccggaag
    21421 attttgtgaa gtgagattat ggttgttgat aaattgtatg cagcattaga tatgcaacta
    21481 aaattgattg cgacggtgtt ataaagaaca ttcctgtaag cacatataac aaactaatat
    21541 acgcctataa taaaagttca ttcttaacag atacagaata agaggaaatg ccgttatgag
    21601 tgaaatatac tgcattgcaa ttgcagtcat tatcgttggt tacgtttatc taatgatcag
    21661 tgtaattact gcaccacaaa aattgtttcc tatacttcag ctaataactc taataggtat
    21721 cagttcgtta ttttctttta tgtcattcaa gagcgaaagc atgtggacgg gtgagcctga
    21781 attattagtt gcgattatgt ttggcacttt ttcagcaaca ctgatttttt acatgtttaa
    21841 aattttgatt cgcgc
//
