LOCUS       NZ_KY770025            34975 bp    DNA     circular CON 24-JUN-2024
DEFINITION  Escherichia coli strain ICBEC13AM plasmid pICBEC13AM, complete
            sequence.
ACCESSION   NZ_KY770025
VERSION     NZ_KY770025.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14227849
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34975)
  AUTHORS   Fernandes,M.R., Sellera,F.P., Esposito,F., Cerdeira,L. and
            Lincopan,N.
  TITLE     Colistin-Resistant mcr-1-Positive Escherichia coli in Public
            Beaches, an Infectious Threat Emerging in Recreational Waters
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 34975)
  AUTHORS   Fernandes,M.R., Sellera,F.P., Esposito,F., Cerdeira,L. and
            Lincopan,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAR-2017) Microbiology, USP, Av. Prof. Lineu Prestes,
            1374, Sao Paulo, SP 05508-900, Brazil
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Assembly Name                     :: ICBEC13AM
            Coverage                          :: 125
            Sequencing Technology             :: Illumina
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009973935.1-RS_2024_06_24
            Annotation Date                   :: 06/24/2024 03:44:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 43
            CDSs (total)                      :: 43
            Genes (coding)                    :: 38
            CDSs (with protein)               :: 38
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 1 of 5
            Pseudo Genes (multiple problems)  :: 1 of 5
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KY770025.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..34975
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="ICBEC13AM"
                     /isolation_source="seawater"
                     /db_xref="taxon:562"
                     /plasmid="pICBEC13AM"
                     /geo_loc_name="Brazil"
     gene            138..653
                     /locus_tag="HTM10_RS00005"
                     /old_locus_tag="ICBEC13AM_00001"
     CDS             138..653
                     /locus_tag="HTM10_RS00005"
                     /old_locus_tag="ICBEC13AM_00001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            758..1300
                     /locus_tag="HTM10_RS00010"
                     /old_locus_tag="ICBEC13AM_00002"
     CDS             758..1300
                     /locus_tag="HTM10_RS00010"
                     /old_locus_tag="ICBEC13AM_00002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            1297..1548
                     /locus_tag="HTM10_RS00015"
                     /old_locus_tag="ICBEC13AM_00003"
     CDS             1297..1548
                     /locus_tag="HTM10_RS00015"
                     /old_locus_tag="ICBEC13AM_00003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            1535..1762
                     /locus_tag="HTM10_RS00020"
                     /old_locus_tag="ICBEC13AM_00004"
     CDS             1535..1762
                     /locus_tag="HTM10_RS00020"
                     /old_locus_tag="ICBEC13AM_00004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            2605..2955
                     /locus_tag="HTM10_RS00025"
                     /old_locus_tag="ICBEC13AM_00006"
     CDS             2605..2955
                     /locus_tag="HTM10_RS00025"
                     /old_locus_tag="ICBEC13AM_00006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            3260..3508
                     /locus_tag="HTM10_RS00030"
                     /old_locus_tag="ICBEC13AM_00007"
     CDS             3260..3508
                     /locus_tag="HTM10_RS00030"
                     /old_locus_tag="ICBEC13AM_00007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            3505..3850
                     /locus_tag="HTM10_RS00215"
                     /pseudo=""
     CDS             3505..3850
                     /locus_tag="HTM10_RS00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            4211..4714
                     /gene="taxA"
                     /locus_tag="HTM10_RS00040"
                     /old_locus_tag="ICBEC13AM_00010"
     CDS             4211..4714
                     /gene="taxA"
                     /locus_tag="HTM10_RS00040"
                     /old_locus_tag="ICBEC13AM_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            4718..>5773
                     /gene="taxC"
                     /locus_tag="HTM10_RS00045"
                     /pseudo=""
     CDS             4718..>5773
                     /gene="taxC"
                     /locus_tag="HTM10_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /name="taxC"
     gene            complement(5943..7142)
                     /locus_tag="HTM10_RS00050"
     CDS             complement(5943..7142)
                     /locus_tag="HTM10_RS00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198547.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="WP_000948429.1"
                     /translation="MLSGFTPRPLKRLFTANQCWTSFLDAGGLRDIEVEAVTKMLACGT
                     RILGVKEFGCDNPDCQHVKYLTNSCGSRACPSCGKKATDLWTATQLNRLPDCDWVHLVF
                     TLPDTLWPVFESNRWLLNDVCRLAVENLLYAARKRGLEPGIFCAIHTYGRRLNWHPHVH
                     VSVTCGGLNKHGQWKKLSFLKDAMRSRWMWNMRQLLLKAWSEGMAMPESLSHITTESQW
                     RSLVLKSGGKYWHVYMSKKTAGGRNTARYLGRYLKKPPIAASRLAHYNGGASLSFRYLD
                     HKTGETATETLTQRELVARLKQHIPEKFFKMVRYFGFLANRVCGEKLPQVYRALGMDKP
                     EPVAKVCYAQMVKQFLSRDPFECVLCGCRMVYRRAIAGLNVSGLKKNARDISLLRYMPA
                     "
                     /name="IS91 family transposase"
     gene            complement(7152..7340)
                     /locus_tag="HTM10_RS00055"
     CDS             complement(7152..7340)
                     /locus_tag="HTM10_RS00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000957857.1"
                     /translation="MLTRKSIDTVLLSVGAEKLSQREWDWMKMLKPMDPPPAMVTTSIL
                     KRRGDTAALTLLQDTGV"
                     /name="hypothetical protein"
     gene            <7456..7635
                     /locus_tag="HTM10_RS00060"
                     /pseudo=""
     CDS             <7456..7635
                     /locus_tag="HTM10_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nickase"
                     /name="nickase"
     gene            7712..8005
                     /locus_tag="HTM10_RS00065"
                     /old_locus_tag="ICBEC13AM_00012"
     CDS             7712..8005
                     /locus_tag="HTM10_RS00065"
                     /old_locus_tag="ICBEC13AM_00012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_060598542.1"
                     /translation="MTEHDAICISGLHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            8002..8217
                     /locus_tag="HTM10_RS00070"
                     /old_locus_tag="ICBEC13AM_00013"
     CDS             8002..8217
                     /locus_tag="HTM10_RS00070"
                     /old_locus_tag="ICBEC13AM_00013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            8573..9193
                     /locus_tag="HTM10_RS00075"
                     /old_locus_tag="ICBEC13AM_00015"
     CDS             8573..9193
                     /locus_tag="HTM10_RS00075"
                     /old_locus_tag="ICBEC13AM_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            9207..9533
                     /locus_tag="HTM10_RS00080"
                     /old_locus_tag="ICBEC13AM_00016"
     CDS             9207..9533
                     /locus_tag="HTM10_RS00080"
                     /old_locus_tag="ICBEC13AM_00016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            9552..12299
                     /locus_tag="HTM10_RS00085"
                     /old_locus_tag="ICBEC13AM_00017"
     CDS             9552..12299
                     /locus_tag="HTM10_RS00085"
                     /old_locus_tag="ICBEC13AM_00017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            12311..13027
                     /locus_tag="HTM10_RS00090"
                     /old_locus_tag="ICBEC13AM_00018"
     CDS             12311..13027
                     /locus_tag="HTM10_RS00090"
                     /old_locus_tag="ICBEC13AM_00018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            13039..14133
                     /locus_tag="HTM10_RS00095"
                     /old_locus_tag="ICBEC13AM_00019"
     CDS             13039..14133
                     /locus_tag="HTM10_RS00095"
                     /old_locus_tag="ICBEC13AM_00019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            14160..14309
                     /locus_tag="HTM10_RS00100"
     CDS             14160..14309
                     /locus_tag="HTM10_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227648764.1"
                     /translation="MSLNWILVFVDKHITSGWSRKRKLITQLVILITGITLFKVLGGIS
                     QSWL"
                     /name="hypothetical protein"
     gene            14648..15334
                     /locus_tag="HTM10_RS00105"
                     /old_locus_tag="ICBEC13AM_00021"
     CDS             14648..15334
                     /locus_tag="HTM10_RS00105"
                     /old_locus_tag="ICBEC13AM_00021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            15331..16239
                     /gene="virB9"
                     /locus_tag="HTM10_RS00110"
                     /old_locus_tag="ICBEC13AM_00022"
     CDS             15331..16239
                     /gene="virB9"
                     /locus_tag="HTM10_RS00110"
                     /old_locus_tag="ICBEC13AM_00022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            16232..17350
                     /gene="virB10"
                     /locus_tag="HTM10_RS00115"
                     /old_locus_tag="ICBEC13AM_00023"
     CDS             16232..17350
                     /gene="virB10"
                     /locus_tag="HTM10_RS00115"
                     /old_locus_tag="ICBEC13AM_00023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            17352..18380
                     /gene="virB11"
                     /locus_tag="HTM10_RS00120"
                     /old_locus_tag="ICBEC13AM_00024"
     CDS             17352..18380
                     /gene="virB11"
                     /locus_tag="HTM10_RS00120"
                     /old_locus_tag="ICBEC13AM_00024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017226.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            18367..20229
                     /gene="taxB"
                     /locus_tag="HTM10_RS00125"
                     /old_locus_tag="ICBEC13AM_00025"
     CDS             18367..20229
                     /gene="taxB"
                     /locus_tag="HTM10_RS00125"
                     /old_locus_tag="ICBEC13AM_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            20238..20660
                     /locus_tag="HTM10_RS00130"
                     /old_locus_tag="ICBEC13AM_00026"
     CDS             20238..20660
                     /locus_tag="HTM10_RS00130"
                     /old_locus_tag="ICBEC13AM_00026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            20644..20949
                     /locus_tag="HTM10_RS00135"
                     /old_locus_tag="ICBEC13AM_00027"
     CDS             20644..20949
                     /locus_tag="HTM10_RS00135"
                     /old_locus_tag="ICBEC13AM_00027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_001350475.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            <21062..21256
                     /locus_tag="HTM10_RS00140"
                     /pseudo=""
     CDS             <21062..21256
                     /locus_tag="HTM10_RS00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            21260..21832
                     /locus_tag="HTM10_RS00145"
                     /old_locus_tag="ICBEC13AM_00028"
     CDS             21260..21832
                     /locus_tag="HTM10_RS00145"
                     /old_locus_tag="ICBEC13AM_00028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001198960.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            21837..23990
                     /locus_tag="HTM10_RS00150"
                     /old_locus_tag="ICBEC13AM_00029"
     CDS             21837..23990
                     /locus_tag="HTM10_RS00150"
                     /old_locus_tag="ICBEC13AM_00029"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            23987..24193
                     /gene="hha"
                     /locus_tag="HTM10_RS00155"
     CDS             23987..24193
                     /gene="hha"
                     /locus_tag="HTM10_RS00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            24211..>24672
                     /locus_tag="HTM10_RS00160"
                     /old_locus_tag="ICBEC13AM_00031"
                     /pseudo=""
     CDS             24211..>24672
                     /locus_tag="HTM10_RS00160"
                     /old_locus_tag="ICBEC13AM_00031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            24762..25466
                     /locus_tag="HTM10_RS00165"
                     /old_locus_tag="ICBEC13AM_00032"
     CDS             24762..25466
                     /locus_tag="HTM10_RS00165"
                     /old_locus_tag="ICBEC13AM_00032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            26236..26331
                     /gene="dqlB"
                     /locus_tag="HTM10_RS00220"
     CDS             26236..26331
                     /gene="dqlB"
                     /locus_tag="HTM10_RS00220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_284696714.1"
                     /translation="MINXLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            26994..27641
                     /locus_tag="HTM10_RS00170"
                     /old_locus_tag="ICBEC13AM_00036"
     CDS             26994..27641
                     /locus_tag="HTM10_RS00170"
                     /old_locus_tag="ICBEC13AM_00036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            27716..27985
                     /locus_tag="HTM10_RS00175"
                     /old_locus_tag="ICBEC13AM_00037"
     CDS             27716..27985
                     /locus_tag="HTM10_RS00175"
                     /old_locus_tag="ICBEC13AM_00037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            28146..28850
                     /locus_tag="HTM10_RS00180"
                     /old_locus_tag="ICBEC13AM_00038"
     CDS             28146..28850
                     /locus_tag="HTM10_RS00180"
                     /old_locus_tag="ICBEC13AM_00038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_225236207.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLQIINTLKCIFSMGLRND
                     CLIKFLKYFCIA"
                     /name="DUF2806 domain-containing protein"
     gene            28944..30569
                     /locus_tag="HTM10_RS00185"
                     /old_locus_tag="ICBEC13AM_00039"
     CDS             28944..30569
                     /locus_tag="HTM10_RS00185"
                     /old_locus_tag="ICBEC13AM_00039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     gene            30617..30940
                     /locus_tag="HTM10_RS00190"
                     /old_locus_tag="ICBEC13AM_00040"
     CDS             30617..30940
                     /locus_tag="HTM10_RS00190"
                     /old_locus_tag="ICBEC13AM_00040"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172690333.1"
                     /translation="MGGGVGFVMPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVA
                     DWFYLGMGHWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKRAMLSLPSG
                     LSQ"
                     /name="hypothetical protein"
     gene            30937..31362
                     /locus_tag="HTM10_RS00195"
                     /old_locus_tag="ICBEC13AM_00041"
     CDS             30937..31362
                     /locus_tag="HTM10_RS00195"
                     /old_locus_tag="ICBEC13AM_00041"
                     /inference="COORDINATES: protein motif:HMM:NF013718.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_112923073.1"
                     /translation="MTKFRVRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTL
                     PYLPMLDSMRNTIPDKCFPAAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCY
                     KMIIGDHFLSHTVVSMMLAWAMSAGLAWVFFKKGEQV"
                     /name="phosphatase PAP2 family protein"
     gene            complement(31753..32280)
                     /locus_tag="HTM10_RS00200"
                     /old_locus_tag="ICBEC13AM_00042"
     CDS             complement(31753..32280)
                     /locus_tag="HTM10_RS00200"
                     /old_locus_tag="ICBEC13AM_00042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(32415..32819)
                     /locus_tag="HTM10_RS00205"
                     /old_locus_tag="ICBEC13AM_00043"
     CDS             complement(32415..32819)
                     /locus_tag="HTM10_RS00205"
                     /old_locus_tag="ICBEC13AM_00043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(32832..33698)
                     /locus_tag="HTM10_RS00210"
                     /old_locus_tag="ICBEC13AM_00044"
     CDS             complement(32832..33698)
                     /locus_tag="HTM10_RS00210"
                     /old_locus_tag="ICBEC13AM_00044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473366.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001353743.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGVKDYKYPDYPAF
                     KRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFD
                     KMYPPEN"
                     /name="replication initiation protein"
     ARG             28945..30566
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(32833..33704)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4719..5809
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="96.978"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          13040..14106
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.6999999999999997e-172"
     Typing          14649..15331
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          15332..16236
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          18368..20226
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aaaacgtgat aacaatcact tatcgagtaa aaaaacggga gaaaacttgc aaatacgact
       61 taaaggtcgt attattgttt catcgaaagg ggaatggccc ctctcacaat agcccagcag
      121 ggcaggagat taaaaaaatg aatatccagg aagcattaaa cgtttttgga ttatccggcg
      181 aattaactga aaaagatatc aaagcagcat acagaaaagc cgctttaaaa tatcatccag
      241 atcgtaaccc gttaggggct gaactgatga aagcggtaaa tgcagctttt gatgtattga
      301 tggcaaatat tgataaaata aatcagttcc agagcactga tgaacatgca cgatataatt
      361 acggtgatga cctggaaaaa gtattaaacg ttctttctgg tttatctggt ctggtatttg
      421 aagtgatagg taactgggtc tggattagtg gagaaaccat tacacataag gaaactttaa
      481 aagaaatcgg gtgtaaatgg gcggcaaaga aaaaacaatg gttttatcgt ccagacgaac
      541 ataaaagtta ctggaatcgt gaagaacaca cgatagaaga aatccgcgca aaatacggta
      601 caaccggaca gcgcagggcg acagggtggc aacgcgtgga aaccagagcg taaccagaac
      661 gggggcgaga agcccccgat attatagcca gcccgtcttt tggggcatcg aacccaaaaa
      721 gacgggaaca gcagccacgt agcaaaaagg gaaacagatg aactcttttt ttgaacaata
      781 tcaccctgtc tttgaagttg tctgccgtat cctggggaac ggctggcgcg tgaacaaact
      841 tgatgattgt tcgtctcgta taaaactgac gtcaccgcag tttaaaaatt actctgtgca
      901 tattcggatg gaaaaagacc gcttttctgt ggtggggagt gtggatagtc gttcctggcg
      961 tagtccgcat catgtttgca cgttatccag aaaacggaat cccgttgata ttgcagccga
     1021 tatcgagcga aaaattctgg taaatgcttc gcaggaggtg ttacaggcga ttgagtatga
     1081 gaaacaccag gtggaaaaaa aggacgaaat tctgatcctg aaaggtatgt tatcgcaact
     1141 tgtccagctt gaaagctggt atggggcatt gacaggcttt aaagctgaaa acggattgaa
     1201 cggtaaagtc accgaacagg gcgacagtta tgatttacag attcggggct tgagtataga
     1261 tcaacttgtt aaaattacag ggtatttgaa acagttatga gaaaaaataa aggtgatgtg
     1321 acttattttc ttgaaaaaga aggtgacaat tacaggctta caaaaaggat aaaagccaga
     1381 acaaatgtta aaatcgggaa caaaactacg aaaattacat tgtatgatgc tgtactgaat
     1441 gagaatgaat tacaacatat tgattttacg tgtgccggat taagggaaga cgatgagacg
     1501 ccagttaaga atttaattaa ggagtttatg ttaaatgaaa cccgataata cacctgaaaa
     1561 tgtaaaaaaa ttacgtttaa aagcaggatt aacacaaaag gaatgcagtc atatttatgg
     1621 tgttgggcta agaacctggc agaaaaaaga ggaagttaat actcaaaaca gtcaaagtct
     1681 gtcactggtt gagtttgagt ttcttttgtt acttgcagga gaacatcctg aatacgtgct
     1741 ctgcaaaagg gagtcaaaat aaaatgacct gtgatggttt tatattagta cctggagttg
     1801 cgctcgtagc tcgctgacgc tcacacgcgc agtacagcgc cccgccatgc tgcaatgcac
     1861 cagggcgggg taaactcgct tgcgctcgcg ctaactgcgg cattctgcgg cgcaaatcag
     1921 cataatcatg gcctgctggt cagttgggct ttgcagggtg aagggatggc ctgtgcaccc
     1981 tggtacgttc gtcagcggct gcgccgcgct tcggggcgat gtggctcctg tgctgccctg
     2041 gtattttcgt tcgccccttc catccgctta cgcggattaa aaaacgtgat aacaatcact
     2101 tatcgagtaa aaaaacggga gaaaacttgc aaatacgact taaaggtcgt attattgttt
     2161 catcgaaagg ggaatggccc ctctcacaat agcccagcag ggcaggagat ttaaaatgaa
     2221 atgctcatct gtttttactt caaccactaa tcatgttttc acattcgaac gagtaacgct
     2281 ttgcactatt atccttatgc ataaggatac tggacaacag tatgttgtca tatttactga
     2341 taacaataaa attcgtgact ataagccgga attgttcctc agtttggcga acttaagcag
     2401 agtgatgttg atttagtcct tttctacagg gacgaatatg aaaaatattt tgattcatta
     2461 aaagatggcg atgaatgctt gagttttaaa gattttattg agtgtctttg ttaagcatta
     2521 tgaatgcagg ggcatccctg cattttctgg aaatttcaat attgattctg aaattgtcta
     2581 ttaacatcaa tgcaagggaa attcatgaaa acgttaaaac aagccgcaat gcagtttgca
     2641 tctgatctgc gtaataatcg ctgttttaaa gctgcttata atgatgctct gttagagctt
     2701 gatcgggaag atttaaacgc cattgtacaa tgcacatttc tttttgagcc aaaacgaaca
     2761 ttagccgaac ttgataaatt aattaaaaag atagaagtag aagaagatta tgagttttgt
     2821 gtatcccttg ataaaggtaa aggattacac gaagtcagaa catttaaaag tgagcgtgag
     2881 gcgttggatg cttatcgcat tttgactctt tacggataca cagtaactat agaaaagaag
     2941 gagggtaatg actgactatt caaggtgtga tcaggttgtt ccaccaacct gatcacgtta
     3001 tcgacaatca aaactgaatg aggtttttaa atgtcaacgc ggcagatcgt acagcttgct
     3061 gattcccttg tcaaaggctg ggaaaccaga attccggcaa tgaaatttag cgaatgggat
     3121 caattccggt ggtggttaaa ctacttgcaa gggtatgaaa tgttttaaat aaaaaaaggg
     3181 gctttctgcc cctttgtatt ttttgacaaa aatgccatgt gtaactataa ttagttgcat
     3241 atctataggg gatggattta tggggaaaac agataagcta ctggcaaagt ttttaaacag
     3301 taaaaaaacg tttgaatggg atgaactggt cgttttgttt tcctctttgg gatatgtcaa
     3361 aaaggaaatg caggggtcaa gagtgcggtt tttcaatgct gaaatcaatc acaccatatt
     3421 aatgcatcgt ccacatccgg aaagttatat caaaggtggt acgctgaaag caattaaaca
     3481 gaatctgaaa gaggctggat tattatgaaa catttaaaat ataaaggata tttaggcacg
     3541 gttgaacccg attttgaaaa taatgtcctg tatggaaaac tggcgtttat tcgggacctg
     3601 gtaacttatg aggcttctac attagctgaa ctggacagga gtttaaaaca tctgttgatc
     3661 tgtatttaca gtcttgtgtg gaggatggaa aggaacctga tacccgttta aaggcgtgtt
     3721 taacgtcagg cttgatccag aactgcatcg tcgggtagca gaaatggcga tggaagaaga
     3781 tttatcgttg aatgcctttg ttaataaggc tctggaaaaa gaagtcagca atcatcgcgc
     3841 aggggcttaa ttgcccttgt ttttatgccc tgtaagggca tgggaggcgc tttgcgccgg
     3901 aagccccgca gcgcagcgag gacttaaaaa gcgttacggc ttcagccgta acaattccca
     3961 gccctgccag gcctgttttt tctttcacaa atctttcagc tatacgtttg cctgatggtc
     4021 gaagacgaaa gaatctttca gcaacgaaat ctggacatat gcagcgacga ttttatagcc
     4081 aggcacagtg ccacatatgg tacaatcaat gcaggataga caatccgatg tcaaatgtta
     4141 acatttgaat cagattgtcc aaaaacgatg tttttgcctg tgcctgccgc aggctctgtt
     4201 ggggtgactt atgaagatga tagcgttcag gctaagtgat gatgagttaa aatttgcaga
     4261 acataacgct attttaagtg gatttaccag tatcaatgct tttgctaagc ataacgtgct
     4321 taatattgaa accaagcctg ttaacatccc agttaataat gaaccagcaa agctggtatc
     4381 agtgcgtctt taccctcatg aaatagaact tgttaaacgt aatgctgctc ttcacggcat
     4441 gagcatgagc agagaaattg ctattcgtgt gcgtcagtct ttgttaaaga gtgaagtctg
     4501 tctttaccct gatgaagtta aggaacttaa aaaactatca actgctgtag atcgtgttgg
     4561 tcgcaacatt cattttatca taaaaggtga aagattctgt acggttaacg atccagattt
     4621 cagaaaagac gttattgaag tgattgaact gtgtaagcaa attgattcaa aacttgaaac
     4681 gttaaccaag agtgttgtta acagatttgg gtgatttatg ggtgtgtatg tagaacagga
     4741 ataccgtatt aaacgcgcta aagggactgg gcgtgatccg aaatctccta agttatcggg
     4801 aagacatata catgccagta aatcggcttt taatcataaa gtcagacatg gtgcggacaa
     4861 gaaagcatat acctggacac ctacaaaaga agtcactttt aaaatcactg gctcaggtaa
     4921 aacagccgca ggcatcaaaa atggtattga ttacattacc cgtaatggtg aacttgaggc
     4981 ttactgttat gatggaaaag gttcagagca aacagggaaa ggagaagact ttaataggga
     5041 gtttacttca actttatcta aaggaaatga ttactccagg acatatcgtg gagaaaacat
     5101 cgatcatgtg aaaaacatgg tcttttcacc accaccagaa gctggagtaa gcagggaaga
     5161 cgctctgaaa gctacggtag aatttcttaa agagacttat ccaaaccatg ctttcgttgc
     5221 cgtataccat gatgataaag aagatcatcc tcatgtacat gttaatatta aacttcgtga
     5281 tgaagaaaca ggaagaagat taagacttac taaatctgaa accaggaagt tcagaaacgg
     5341 ttttcataga aaactgaaag gtatgggata tgatgttacc gctacctgga aaaaagatcc
     5401 cgaacgtaaa cgggagattg agcgattaca ggctgaaaat ccgaaaagac tccggaatgt
     5461 ttacaaggtg gtggattttg gggagacttc atatcagaat aaggcagggg aaaaacgaac
     5521 acctttcctc acttatgaaa ctttaaaagg tggaaaacag gttacgattt ggggtaaaga
     5581 cctgaaaaat catttcgagt ctgaaaagct ccagccagga acgcttatca aagtaaaaaa
     5641 actggctcct acgcttgtac gtagtccaat gtttaatgat gatggaactg ttgcaggcta
     5701 cagggaaacg catcgcaata actggcagat tgaaaatatt gcccttgagc ggaacagaga
     5761 acgtcaggtt cacgtatagg aaattgaaaa accagtcgat accattgtcc acgccttatg
     5821 ccacgtgagc ctttctgctt ttcccaccac tccggtggtt tccctctctg tatggtcgat
     5881 ttttataccg taacaggctg ttttttatac tttcaccgat tcccgggcac acttagcctg
     5941 tgtcaggccg gcatatacct cagtagactg atatcccgcg cgtttttctt cagccctgat
     6001 acattcagcc ccgcaatggc ccggcggtat accatccggc agccacacag cacgcattcg
     6061 aacgggtcac gactcaggaa ctgtttcacc atttgtgcat agcacacttt cgccactggt
     6121 tccggtttat ccatccccag tgcacggtac acctgcggca gcttctctcc acacacacgg
     6181 ttggcaagga acccgaagta cctcaccatc ttaaaaaact tctccgggat gtgctgtttc
     6241 agcctcgcga ccagctcacg ctgtgtcagc gtttccgtcg ccgtttctcc cgttttgtgg
     6301 tccaggtaac ggaagctcag gcttgcccct ccgttgtaat gagccagtcg ggaagccgct
     6361 attggtggct tcttcagata acgacccagg tagcgtgccg tattccgccc tccggctgtc
     6421 ttcttcgaca tgtacacatg ccagtatttt ccgccggatt tcagcaccag gcttctccac
     6481 tgtgattccg tcgtgatatg tgacaacgac tccggcattg ccatcccctc tgaccacgct
     6541 ttcagaagca gctgccgcat attccacatc caccgtgaac gcatcgcgtc tttcaggaag
     6601 ctcagctttt tccactgacc atgcttattc agacctccac aggttacaga cacatgtaca
     6661 tgcggatgcc agttgagacg acggccatac gtgtggatgg cgcagaagat accgggttcc
     6721 agcccccgtt ttcgggcggc atacagcaga ttctccaccg ccagacggca cacgtcattc
     6781 agcagccagc ggttgctttc gaacaccggc cacagcgtgt ccggcagggt gaagaccaga
     6841 tgtacccagt cgcagtcagg aagacgattc agctgtgttg ctgtccacag gtctgtggcc
     6901 ttctttccgc aggacgggca ggcacggctg ccgcatgagt tggtcaggta ctttacgtgc
     6961 tgacagtccg ggttatcaca cccgaactct tttacaccca gtatccgtgt gccgcaggcc
     7021 agcattttgg tgacggcttc aacctcgata tcgcgcagac cgcccgcatc caggaaggac
     7081 gtccagcact ggttggctgt gaacagacgt ttcagagggc ggggagtaaa accggacaac
     7141 atgaggatgg attaaacccc ggtatcctgt agcagggtaa gggctgctgt atcgccacgg
     7201 cgcttcagga tggaggtcgt caccatcgca ggtggtgggt ccatgggttt gagcattttc
     7261 atccagtccc attctcgttg tgagagcttc tcagcaccaa cagagagcag aactgtatcg
     7321 atacttttgc gggtcaacat aaggggatga gtccttaata aaacaggtcc tcagagcata
     7381 catattctgc ggggcgtgcg gcaacaacag gacgaaccgg ggcggttttc aatttgcagc
     7441 cgccaggctg ccgtggttca tgagcgtgaa accaggcagc cggaagagag cgacgttaaa
     7501 aagcagctat ccagaaaaca tgagcaaggt cacaatatcg ggtttgctct tgaacacggg
     7561 tttacaaagg attcagaaga acataaaaaa ctaagaatac agcaagagag gaactggaaa
     7621 ggcctgggat tttaatttga ttttggcgca ggtgaacaaa gcggctactt tgctcacctg
     7681 ctgatcacaa caacctacga gggaggttat catgactgag catgatgcta tctgcatttc
     7741 tggacttcat caaattttta gtgatgaaga acatttgagt gagcaacaaa aagacattat
     7801 tctgatgtac gcttatggct ataccctgaa tgaaattgct gatttcaaag gactaaagcc
     7861 ttcaactgtc agaaaatatc tcgattctgt aagagctgaa ctgggaggtg tctcgttggc
     7921 agggatcaga acactggtac tcattcggac taatgccctt ctcgtgtcaa gtctttccag
     7981 gatcagtgag agggggaatt tatgaaaaaa tatctgcttt ttgctttgcc gttcttcgtt
     8041 gttggttgta gtgaagaagt aaaaagtgtg gattggtggg ggcagcatct tacggaagct
     8101 aaacaaaagc aggcagagtg tgagaagtct ggctctgatt ctcagaactg taagaatgtt
     8161 aaacaagcat tgtttattca gtctcagaag gatgctccag tccctacatt cgattaacta
     8221 atgtttcaat catactagag cgcccatatg ggcgcttttt tttgcatgat cacacgaatc
     8281 ataatatgac cattttgtca atgttatttg atcgtattgt tgagcattgt tattttgcga
     8341 atcatgttcg catctaaaac aaatccaaaa cacacttata gtggattgat taaatgaagg
     8401 agaaatcaga taagtcatcg gaaaaagggg tttatgtcac gataaaactc gatcccaggt
     8461 tgaatgcatt tatcgaagag aaaacgaaaa catctttgct tagtaagagg aagcaaatta
     8521 tttacttatt aatgcagagt atgcgtattg atggatatat ggagcgttag ctatggcgtc
     8581 tttattccca gccttgttgc tgtgtgcggc gtcagttcat ccggatacga taaatgatat
     8641 tgcacgggtc gagagtggct tcaatcctta tgctgtggct gaaattattc ctgaaaggga
     8701 acgcggtagc tatggcaaaa gtgttatcag tcatatgccc aaaagtaagg aggaagctct
     8761 aacagttatc agagaaattg aaaacagaaa aagacgttat tctgtcggat tgatgcagat
     8821 taccagcagt aatttttctt tttattccac gtccgcagaa aaactccttg attcgtgtga
     8881 aaacttgtct gttttcgaaa agattatcgt ggattgttat aaacgaggga ggagcctgga
     8941 gaatgcgctt agttgttact atacaggaaa ttttagtaac ggtaagcgaa aagaaaaaga
     9001 atttaataat acaagttatg ttgagcgaat tggttataca gggaacgaaa aaaaatatgt
     9061 tgtaccaggt acaagaagca acgggggaga acagcgaaaa aatcgttcac acaatgcgtc
     9121 agttatctgg cccgaaacca ttctgaaatc tgcttttgtt gataactcac atccaacaaa
     9181 agttattaat taacaggact tataaaatgt catttaagaa atcagtatgt aatcgtatca
     9241 gttcatctgt cactgctgta atgcagcgta aaaataaggt agttatggca gtcgccgggg
     9301 caacagttgc atcaccggcc tttgcggatg gattttcaaa agcggaaaca ctgctggaaa
     9361 aggttaaaac agggcttagt ggcctttcac tggtcacggt gactattgcc tgtctgtggg
     9421 tcggctacaa ggttctgttt ggtggaagca cgattcgtga atgctcacct atcatcatcg
     9481 gggcaattgt tatcgccagt gcggctgaag ttgcatcaat gatggttaac taataaagcg
     9541 gggacgatag tatgtctaca ctttataaag cgatgacacg ccctgctatg tatgtgggtg
     9601 ttcctgtcgt ccctcttact gtggttgcag gggcgttatt tctggcgggg gtttatatca
     9661 gcaagctgat ctggctggct attcctgtcg cggtttttgt tctcagaatg atcactaaac
     9721 aggacgacca catttttaac ctttactttc ttaagctgaa aatgctcgga aactcagtgt
     9781 gtaatcgttt ttttggcgca cgagcgttcc tctccggaca atatgaagct gttgaaattg
     9841 atgagtttgt taatgccatg aaactgaatg agcgaatcac tactggtaaa tatataccct
     9901 attcaagcca tgttgataaa aatattgtca aaacaaagaa cggtgattat gtagcgacat
     9961 ggcaactgat ggggattaac tttgagtcaa tctctgcgga gatgttagaa actattgact
    10021 cacaggttgc cactcttgtt cgttcatttt ccggactgcc cgtttcattt tataaccatt
    10081 catgcagggc gagtttttat gatgccttta ccacaaaatc aggtaataaa tatgctgata
    10141 taatatcaga ttgttactat ggttcgatga agaaaaataa attcaagggg aacactcttt
    10201 actttacgct gatctacaga ccagatgggc gtgtagaaaa actggaaaaa cgcaaaaaaa
    10261 gtattaaaga aaagaaagat gatattaaca ttcatgtgaa gagaatgaat gaaatgatta
    10321 atacattctc tggcgctctt gataaattta cctgtaaact tcttggtatg tatgaggaga
    10381 acggaaaggt attttcttct caactgtcat tctataatta tcttctgaca gggaagttgc
    10441 aaaaaatcag agtcactgat tctccggtgt ataacgttct tggtggagtg gatgtatttt
    10501 ttaatcatga taccggacag atatgccgca ttgatggaaa taaattcttt cgttctattg
    10561 aaattaaaga tttctgtagt gagactgcat ccggtgtttt tgatgtgctc cagtattctg
    10621 atgctgacta tattattacg cattcatata catccatgag caaatcagaa gcattgagta
    10681 ccattaaacg tgcggaaaaa cagttaaaga gtacagaaga tgatgcggtt actcaattgc
    10741 aggaactgga aaaggcaaaa aatgatattg tgtccggtga tatatccttt ggttactacc
    10801 atttcacgct aatggtaatg gcggacagta tcagggagct tgacgaatct gtaagtaaaa
    10861 ttacggcaga ctttactgac ctgggcatta ttccggcatt gtcaaccatg tcattgccag
    10921 cggcatattt tgcccaactt ccggcggttt ttcatttaag gccgcgttta tctccggtat
    10981 cgaatgtaaa ttttgttgaa ctggcatcat tccataattt ctaccagggg aaacgcgata
    11041 aaaactgctg gacagaagcg gttgctattc tcaaaacacc aagcaaacag gcgtattatc
    11101 tgaatttaca taactcagta ctgtttaaag atgaaacagg tgaaaagaat cttgctaata
    11161 ctaaagttat aggaacggcg ggttcaggta agacaatgtt tctgtcatat cttgcctgtt
    11221 cattacagaa atacaataac cccgaaactt ttgctgattc tgcaaaaaat aagaagttaa
    11281 cgtgtgtctt tcttgataag gacagagggg ctgaattatg tatccgaatg cttggtgggg
    11341 aatattacac cgtaaaaagc ggtgagccga caggatggaa tccttttgct ctggaggcaa
    11401 caaaacgtaa ccgtattttt gtcaagcaac tgatggagat tctgtgtacc agaaatggtg
    11461 aaagattatc gacaagagaa agattgctta ttagcgaaag tgttgatgct gtgatggatt
    11521 ttcctcctgg cgaaatgcgg gaatatggca ttaccagaat gcttgagcat cttatgcaga
    11581 gagatgatcg ggatgagcag gagaacggga ttatccttcg tttgtcccaa tgggctaatg
    11641 gtcaggctca tggctgggtt tttgataatg ctaaagacac attcaatatt cagcatgtca
    11701 ataattttgg cattgatggc accgagtttc ttgatgatcc gatggtatgt gcaccaatta
    11761 ctttctatct gctgtatcgc attacgcagc ttctggacgg tcggcgtctt gttatcttcc
    11821 tggatgagtt ctggaaatgg ctacaggatg aagcattcag cgactttgtc tataacaagc
    11881 tgaaaacaat tcgtaagctg aacgggctgg ttattccggc aactcagtct ccggatgaaa
    11941 tactgaagaa taagatttca cgggctgtgg ttgaagtatg cagcaccagt atttatctgg
    12001 ctaaccctga tgccgattac aatgattatg tggaagggct taagctgaca ccagaagaat
    12061 ttaatattgt taaaaatctt gatccaatgt cgagacagtt cctgattaaa aaaagcagtc
    12121 ttaaaaaggg ggatggtaaa tcattttcag cacttgcgac actcgattta tcgggacttg
    12181 gtggatatct gaaaatattg tctgccagtg cagataatct ggaaattttt gaaagtattt
    12241 atcatgaagg aatggagcct gatgactggg ttcctgaata tctcgaacgg gcaatctgac
    12301 aggtgaattt atgaaacgtg taaaaacatt gatgctgata tcattattga cggcttcatt
    12361 ttatagtagc gcaggaattc cggttgctat tgatgccagt ccggaatggg ctgttgaagc
    12421 cgcaagatgg acagaacgac tcaaacaatg gtccgaaact gcgcaacatt atcagagtca
    12481 gattcaggca tataaagacc agttagccac ggcaacaggt ataaggaata ttgcggcatt
    12541 cacaaatgaa ctaagtaatc tacaatcaga actgacaaat atttataagc aggggaacag
    12601 ttatatttct gattttacca gtaatcccga aggtgcattg agcagccagg ctaaaaatct
    12661 gttcagcaag tatggagcct tcgatatgtg taatacgggc tatgaacgta atgataatct
    12721 ctgtaaagca cggattgtgt caacggctgc cagtattgaa cagggaaatg agatcaataa
    12781 gcagttatca agtgcaatgt ctcagattca gagtttaagt agccgaattg aggcttcaaa
    12841 ggatatcaaa gaatcccagg atttggctaa cgcattacag gcgcagtcgt taaaaatgca
    12901 ggcgataaaa atgcagtatg atgtctggaa taataaaaat aaagcagatc atgagatgtt
    12961 ggtcacacaa gaacaagagg cctttattaa acagcagaaa gaagctgaac cattaacttt
    13021 tgattaaaag gtggatatat ggctcagggg tttttcgtta aatataattc taccgttatg
    13081 gattcggtag ataaaatcag ctccagttat caaacacaat ttgctaatga tattatgtcg
    13141 ttagcaacgg tatcggttac gttatatgta ctatggaaag gatatcaaat acttgccagt
    13201 aaaactcaga cgcccttgca ggatttagta tgggatctat caaaatttgc aatcataatc
    13261 atgtttataa ctaatgcgga tgggtattta actgcggcta ctgatgcgtt gcaaggcatg
    13321 aaagatggtt tttctggagg ggtgagtgtc tggcaaactt tagataactt atggaaaagt
    13381 acgcaaaatc ttggtgcgga aatatactct ttagataaat caacatatgt taaagatcaa
    13441 ggtgtagttg gtcagttttt aatatggact ggctcgctta ttttaatggc tgttagtgtg
    13501 gttgtttttt taacagcaga tgtaacgatg aaactcctga ttattacagc accgatattt
    13561 atcttttgtc tcatgtttgg ttttattcgg agcatgttta ataattggtt acaatcgtta
    13621 ttctccagta ttctgacagt tctatttgcc agtttagtga ttcggatagc aatggatttt
    13681 caagggatga tcctttccca tgctattcgt gctgcacaaa cagggaatgt aaatcttgta
    13741 tctacaggtg ctatgggctt tatggctggg tttttggggg ctttattggt tcttatagct
    13801 aaaggttttg ctgtccagtt agcaggtgca ggtgttgaag gtgctgttca gggcgcagcc
    13861 atgatggggc tgggtgctgc tggtatggct actggtaagt ctctgatgct tggcggtcgt
    13921 gctggtttag gttttggctt agggatggcc ggaagaacgg gcatgaattc tttatcaggg
    13981 aaagcaggga atctgatggg gcgtggtgcg cgaacagccg ctgaatgggc gggtgaaaag
    14041 ggatatcagg cgctggctcc gacaggtgct ttggggatga aggcgagaag acttgcatcc
    14101 ctggaaaaag cacgagcgag gaacgccgca tgaaaataat gaaacgtttt ttttatgtga
    14161 tgtccctgaa ctggatactg gtgttcgttg ataaacatat cacctccgga tggagcagga
    14221 agagaaagct aataacccag cttgttattt taatcacggg aattacctta tttaaggtct
    14281 taggtggaat cagtcagagc tggttgtgac atgcttcatt attttgtcat gatactttat
    14341 tttgtcctaa tccttctttt aggagtgttt acctgcttcg caggaataag acttggttta
    14401 gggcttgcgg ggaaatggag aaagggtatg gatcttcgct ttttgcttct tattggtggg
    14461 attctttttc ttcatcttgg cctttatctc ttaaaggtgt tcgtgaacgc ttaataaggt
    14521 gaatttatgc gatgtgtgat tcttttgttt ttcctgtttc agatttccgg atgtaccaca
    14581 aggaataacc ttccttctga tgtttccggc gaactggaac ccattaacca cagccaggta
    14641 atcagttatg agtgaaaaaa tcgaaaagaa gattgagaca gctaaatcct tcgaaagaca
    14701 actctatgca gaaaatgaac ggtctaagaa aaatgcatgg cgtgttgcag tggcagcatc
    14761 attactgtcc ttatgtcttg gggctgcaat ttgtgttctt gtgccattaa aagaaaaaga
    14821 gcttgctatt gtggctgttg gcgaaaaaac aggccgtaca gaactgatta ctcaggttaa
    14881 acaggaaaag atcctgcaat ctgaagcact tgggcggtat tttgtaaaca cgtatattac
    14941 tttacgtgaa ggttataatt atccgtctct tcagtatgat tatgagactg tacagctata
    15001 tagctcgaat acagtaaagg acgattatct tcgtctgtat aacagcgata tggctcctga
    15061 taaaatttat cataataacg gttcttacgt tgcggttgag gtcatctcca atattatttc
    15121 tgacgcaacc gcgccagata aactggcctc tgtgcgcttt aaaaaaacga cgagaaactt
    15181 cacgaccgga caggtttcag tttcatactg gacggctcgt gtgacatatc gttttgaacc
    15241 agaaaagtcg gttaaaagtt ccagtcgtga gcttaatcct ctcggtttta ctgtaaccag
    15301 ttaccagaca gatcgggaag tcagggggga atgatgaaga aattatttat tgctacatgt
    15361 ttattgcttc ctgggcttgt gtattcagca gcgactccgt taccttctgg atttgatgca
    15421 aggatgcaga ctgtgagtta taacggtgcg aatacgaccg ttatccggtc aaagacagga
    15481 tttctcacat cagttgtttt tgatgaaggt gaggctgtta tcagtgcaaa ggctggtttt
    15541 cctgccggat gggaaatcac aaccgatgat aatgttgttt acatcaatcc gcgtcccgtt
    15601 gttcaggaac aggaaggcga tgaaggcgaa aaactgaaaa aggttttcca gccaacagaa
    15661 aaggaatggg atacgaatct ttttgtcaga acaacaaagc ggatttacag tctggatcta
    15721 atccttctgt cagaagaaaa acaagcgcaa cctgcttatg ttgtacaatt ccgctatcca
    15781 tcagaaatag cgaaaaagaa tgcagaagaa gtaaggctgg caaaagaaaa acaggaaaaa
    15841 ctcagacaga agaaactgat ttctgaaagt tttgaaaaag ccgatgcgcc taaaaactgg
    15901 aattatttca tgcgagtcaa tgaaaaatat gacagtcgtc gtatcgcccc tgattttgct
    15961 tatgataatg gcatatttac ctttttaggt tttaactcag ggaaagtatt cccagctcca
    16021 tttgctgtaa gagatggtca ggaacagaca cttgctttta atgtggaaac aaaaggcaag
    16081 tataaaatta tggttatcca caacgttaat gacaaatttg ttttacgcta tggaaacagc
    16141 gttgttggtg ttgtgaataa atctttcgga aaagtattaa ccgaccagag gaatacatct
    16201 tctcctgcgg tagaacgtgt tgaggtgaat aatgactgat atgaaaaaaa cagatgattt
    16261 agttgatgat gcgaatcagt caaagctgga aagtaaaccc gttcatgata tcggtgatat
    16321 caggaacaaa aataatcgta tgcgttctgg ctttctgttt ggtctgatgg ctgtattagt
    16381 tattggtatt tttgcgctga aaacatataa aaattatttt gcagatgacc agcagaaagc
    16441 atcagaatca acaggcgata ccagcatttc tcaggtaagt aaaatccgta ctggtcttgg
    16501 tcagaatttt gaccctgttg agaacaaagc aattatcaat ccaggcgcta ctggttctgg
    16561 taatactgtt tctgacggtc ataaagaagt gccacaggag gggttcagga aatatttgtc
    16621 aatacctgtt gctggtcagg gagggagtca gactggcgcg agtggcagca gcaggacatc
    16681 gcagacatca gagccacagg aagaaaggaa agaatcaaaa gaaaatgtgc ctggtaaatc
    16741 aggaatgaaa gtaactgcga ttaatctcga tcctgatctc tatattgagg aaaacaggct
    16801 tataccgtgt gctttaacca cacgctttgt ttctgatgtt gcaggtcgta tcagttgtgt
    16861 ttttacagaa gatgtatgga gtgctaatca ccacacaaaa ttactggaac agggaactaa
    16921 ggcttttggt cgttaccaga ccggaacgct gaatcatgga cagggcagaa tgttcgttat
    16981 gtgggagcag ttgcggacgc ctgataataa acgaatcgat atggtaaata cagcagcagc
    17041 tggtcccctg ggagaagcgg gcattgatgg atggatcgat tctcacttct gggagcgttt
    17101 tggtggttct cttatgctca gtatggttca ggatgtagcg gcggcggcgg cggataatgc
    17161 acctggtaaa gatcgtaatg tggattatac cgaaaactca cgacaggcaa tggctgaaat
    17221 ggctaaagtc gcacttgaga attcgataaa tattcctcca acaatgtata aaaaccaggg
    17281 tgacataatc actattatgg tcggggaaga cattgatttt tctgatatct atgagttaaa
    17341 ggtaaaatag tatgagtggc gttattcctg tcagcattag caataaatcg ctcgattttt
    17401 ataaaaatca agtattccag tcttttcttg atattgaagg gctaacagaa attgctgtca
    17461 accgtcctgg tgaaatctgg acggaaatta atggtgactg gacattccat aataatgaca
    17521 gtgtgacctt tgatttttgt aaacgttttt ctcatacgct ggcatcattt cggggagatg
    17581 aaatcggcga gaccaagcca ttactttcag caacactgga atcaggagaa cgtgtacagg
    17641 tcgtttttcc tcctgcatgt gagagaaata ctatttcaat cactatacgt aaaccatcga
    17701 cacggcagat aacacataaa gaatatgtgg cgaacggttt ttatgattat gtccagtcag
    17761 gaaaaaaaca caggacatac gatgatgagc ttcttgattt attcagagcg agaaatatcg
    17821 ctgcttttat ggagcttgcc gtagcagcag ggaaaaccat tgtatttgcc ggagcaacgg
    17881 gttccggtaa aacaacttat atgaagagtc ttatcgattt cataccattg aatacacggc
    17941 tgattacgat tgaagatgca gaggaaatca aattttttat ccataaaaat tatgtgcatc
    18001 ttttttaccc ttcggaatcc ggcagtgatt ccggctctat cataacagca gcgaaattaa
    18061 tcaaatcctg tttgaggatg aaacctgaca gaattttact ggcggaaatt aaaggtggcg
    18121 atgcctggga ttttgtgaaa gttgctggtt ctggtcacag tggaagcatg acgtccattc
    18181 acgcggcctc ggcaaaagat gccatcattc agatggtgac aaaatgttat cagaacagag
    18241 aatgtcagaa tcttcctttt gatgttcttc gtaaaatcat tatggacagt attgatattg
    18301 ttgttcatgt aggcagggat ggtgttgtca ggcatatgag cgacatctat tacaaagggg
    18361 ctgaatgtga aaacttttaa taagtcgcaa tctgttttta tattcgctgt tatgcttgtt
    18421 gcggcatggt ttgcaggttc atttattttc tttgtgcttt acttcagcca gataaagaat
    18481 ctgaaaccat tgaaggctgt gttcagatcc attgatgcgt acaggatgga tatttttaca
    18541 gacagcctta ctttatctgt tgtgactacg gatatcagag ttttagcctt tgttgcactt
    18601 ggagcaggat ttgtcgtgtc tcttatcatc cctgttgcgg cgttgataaa actgaacgag
    18661 aagaaagaaa atattttcgg tgatgcgcga tttgcaacaa ttaatgatat tcgtgagtct
    18721 aacagtttca cgcttgacgg tgacgaaaaa gacgggatta tcgttggtat aaaagacaag
    18781 aaaatcatac gctatgtggg agcagcattc agtgctatgg gagccggaac aagggctggt
    18841 aaaggtgctg gtatagtcat cactaatctt atgaagtact ggtggagtgt tattattctc
    18901 gatccaaaaa gggagtgttt taatatcacc agtcttatca ggaaggtgat tttaggtcat
    18961 gaggtttata aatttgatcc ctttagttcg gtaacgcacc gctttaaccc tttgtattat
    19021 gtcagcatgg gaacgagtga aggttttaat cagcttgaaa atctttcgtt gattatttac
    19081 ccctataaga cagatggtgc ggatgctggt agctatctta ataagacggc gggtggtgtt
    19141 tttaaatctt atgctgtcgc tttatggttt atgattaaga atgataaggc tggactaaaa
    19201 acgcttgata ttgagcctgt cttctcaatg tctaaaatta atcagctttt tgagcgtgca
    19261 gaacccgaac atcttctttc attcatgaat gatattcgtt cagaattaag ggggaaagac
    19321 aaaacgcttg ctgatattgg tgtcgctggc cttaaggcat tcattgagat ggaggataaa
    19381 acaaaagcac aactcaaaag caactttctt aatggattat caccgtttgc taaccccaat
    19441 gtggcaaatg ctactgatgg aaatgatttt gatttgcggc aggtgcggaa aaagcggatg
    19501 acaatttatt tctgtatttc tggtgataat gccaggttgg ctgaaaaaat aacaaatatt
    19561 ttctttcagc ttgctataca ggtgaatctt gaaaagatgc caacggatga tccggaaata
    19621 aagcatgact gcctttttct actggatgaa ttcccgtcaa ttggtgctgt agattacatc
    19681 aagagtaaat ctggtctcat tgctggttac aagctgaaat tgttgattgt ttaccaggtc
    19741 ggctctcagc ttgaggaaat ctacagttat gcaggcagta aaacattact ggcaagtgca
    19801 ccctgcaaaa ttgtttattc cgcttctgat gttaaagatg cgcgggagtt atcagaagcg
    19861 atggggacac gaacagtaac tatcggttcg aaaagcaaaa gtcgtagtcg tggaggaaca
    19921 tcgagatctg aatcagaaag ccttattgag cgtccactgg taacaacaaa tgaactactt
    19981 acactgaaat ttagtgaaga aatcctggca atgaagggag aaaacccgat tcgttgtgaa
    20041 aaggcattct actatctcaa tgagtatttc tttggtgact ttgtgaaggt tgctccggaa
    20101 cttgcaaaca ttttccccag gaagaaagga aagctggtta tgcctccaca gaaagtattt
    20161 gaaaatgaaa tcgtcgcaaa agggtatctg gtagtaaaag atgttcctga tctcgataaa
    20221 gcggcataaa ggagaacatg atgaagaagt tagtgttttt attgatttcc attcttgctg
    20281 gttgttcatc accgccagag ccaacacccg tgcagtttga aaaggcaaat gaagtgatca
    20341 atccctcatt gccatatgtc cccgattttc acggtgtcat aaagtcagac gttagcggta
    20401 aaggatgggt ttatgagatc acttccttat ccggagtaca ggccagaacg ccgacgtttt
    20461 attacgctct ggctcatgcg gacaggattg tagtgacaac acatgatgct gggctgtggt
    20521 ttcgaatcag agatctgttg aagatggaag gggcaacagc agtcgtggaa tggcgaaacg
    20581 agaaaagttt tttacctgaa caggtaaaaa tagttttcat taaagcacaa aatgaggtga
    20641 aaaatgactg gaaaaaatag agtggtttta ccagccttgc tggcgttagg attaatatca
    20701 acaaatgcta atgcatctga cccttgcgct tcggtacttt gcttatatgg aaaagcagtc
    20761 gggcaaggtg gagggagtga atgcagaagt gctgaaaagg atttttttaa tattctgaaa
    20821 aagaaaaaag gaagcattcg ctggagtaaa acttttgatg cccgtaaagc atttctgaat
    20881 cagtgttcaa cggctgatcc tgctgctata tcaaaaatca tgagtaagtt tggtcgtgtc
    20941 agaggttaat taaaacctga taaccgcgcc aacgggtatc agggtactgc aagtatcaca
    21001 tttcgcgcca acgaaatgtg atgattagtt acaatcactg aggttagaaa tgaaagtaac
    21061 caaatctatt atagctattt tattgtgctt atctgctggt agtgcataag tggatgtaat
    21121 aaaaaatgct cgtgcctttt tgaaaggaac cctcgatctg agcgttcagg aagcagatga
    21181 agatatagag gaaagggaag aactttataa aaagaacggg gcacaacctg actatttaag
    21241 ttacctggag gattaacaca tgcaatatgc attgtttgat ggatttgaac gaaagttttt
    21301 gctggatgct cttgaattcg gtgttctgaa ggactggaaa gaaaatccgg taaaagaact
    21361 tcctgatatt gatgaatctg ctcacccctt ccatatctgt tatggtggat atttattaaa
    21421 ccctggtgtt tcagattcag atattagcag aaaaataaaa gaccaggcag gattctggct
    21481 ggcagctatt gatgataccc gcatggattg tcattcaata gcttattatg atattcacac
    21541 actccctctg atttcgtgtg gtcatcaaaa gatagttcct tttgccgcgt taataaaagc
    21601 tgatgaatgc atcatttcaa aaattgcttc gtattctggt tttgctgtaa cagccttttt
    21661 gagaattaaa gagtgggata ttgcaactaa tatacttaac cgtgagggaa tttttgcctt
    21721 taatggctgt gagcgcagat tcagagtagt aagtaaagat aactggcaac atacagtatc
    21781 ggaagaacgc gctatccgtt gtgccaaaag attaattcaa tgtaaaggat aacaaaatga
    21841 gactttttat cgcagaaaaa cccgcagtag caaatgatat tgttaaggca cttggtggca
    21901 attttacccg ccatgatggc tggtttgaaa gtgataacgc cattgtgact aactgttttg
    21961 gtcatattat cgaatcacaa ccgccggaaa actataatcc tgaatacaaa gcctggaagg
    22021 ttgaaacgct tcctttacgt ctttatcccg tgaagtatca gcctgttgaa agtgcagcaa
    22081 aacaggttaa aacgattctc gaacttatca gacgtggaga cgtgactgaa attgttcacg
    22141 ctggcgatcc tgatgatgag ggacagctac tggttgatga agtcctggaa tatgcaggca
    22201 acacaaaacc cgtaaagcgc gttctgatta acgacaacac gcttccggca gtgaaaaagg
    22261 cactggcaaa tcttaaagac aatcgtgatt tcaaaggact ttaccttaag gcgttggcgc
    22321 ggtcagttgc cgatgccgtc tatggcttct ctatgacacg tgcgtacacc attccggcaa
    22381 aagccagagg atatcagggc gttctgtctg tcgggcgcgt ccagactccc gttcttggcc
    22441 tgattgtgaa tcgtacccgt gctaaccaga accataaatc cagtttttac tacaccatga
    22501 ccggagtctt tcagcgtggt gctgatgtta tcagggcgaa ctggaagcca ggggaatttg
    22561 ctccgctgac agaccgtaaa ttacttgata aagcgtgggc agacggaacg gctgcatccc
    22621 ttgcaggaaa accggctaca gttgaagcag cagcaactga tgataaaaaa acggctgcgc
    22681 cgttgccgtt taatctggtc agactccagc aatacatgaa caagaagttt aaaatgacgg
    22741 cacaaaaaac gctggatatt acgcaacaac tacgcgaaaa atataaagca attacgtata
    22801 accgctctga ctgctcatat ctttcagatg aacaattcag cgaagcgccg caggttatcg
    22861 atgccctgaa atcagtcttt cctcagtcgc tggatattga ttctgcacgt aaaagcaaag
    22921 cgtttaacag tgcaaaggtg actgcgcata ctgcgataat cccgaccgcc agtgtgcctg
    22981 atgttaacgc actcagcacc gacgagcgca atgtttacct ggcgatcgca caacactatc
    23041 ttgttcagtt catgcctgaa aaagcatacc aggaagtatc ggttgccatt cagtgtggtg
    23101 atgagtcgtt ctatgcccgt gccagaaaaa caactgacag cggatttgag gcgtttcttg
    23161 gcgcggaaac cacagacgaa ggtgaatcag aagataatga tgattccgct tttgaactgc
    23221 tctgtaaaat tcgcacagga gaaacactga cgacaaaaga agttattgtt aatgagaaga
    23281 aaacaacacc gccgccgtta ttcaccgaag cctccttgct tgctgcgctt gttcgtgtcg
    23341 cggattttgt cactgatcca acaattaaaa aattgttgaa ggataaggat aaagacaaaa
    23401 aagatgaaca tggtggcatt ggtacgccag ctacccgcgc agccattctg gaaacgctga
    23461 agaaaagaaa ctatatcacg ctggaaaaag ggaaacttat tcctactgat accggatatg
    23521 cgcttattga tgccctgcct ggtatagcgg ttaatcctga tatgacagca ttatggtctg
    23581 aaaagcaggc tgccatagaa aatggcgacc tgacggttga acagtttatt aatgatctgt
    23641 acggtgaact gacaggcatg atttctgatg ttgacctggg cgagatgaag attgaacccg
    23701 ctgcgccagc agggcagttt caacgcctgg actctccctg cccttcctgt ggtaaacata
    23761 ttgttatcag gccgaaaggt tatttctgta ccggatgtga atttaaaatc tggagtgagt
    23821 tttctggtaa gaaaatcacc caggcacagg ccgaaaaact ggttaaatca gggaaaaccg
    23881 atttgattaa gggatttaaa aagaaaagtg gtggaacgta tgatacagtt cttgtccttg
    23941 aggataagaa aacagggaag ctgggttttc cggcaagggc taagaagtga aaacaaagca
    24001 ggaatggctt tttcagttaa gaaaatgtac atcaagagat actcttgaaa aagttattga
    24061 gattaaccgt tacaaactgc ctttatcaga atcagaggca ttttattctg ccgcagatca
    24121 tcgccgagca gaactggtga tgaataaact ttatgataag gtgccttccg gcgtctggaa
    24181 gtacgtacac taaataagag gattaattat atgagcgaac tgactaaaga agatgaatac
    24241 ggcattatca gccgtactat gatgaatatt cgttcattgc gtgtttttgc ccgtgagatt
    24301 gattttgagc agttgctcga aatgcaggaa aagctcaacg ttgttattga agaacgtcgt
    24361 gaagatgctg aacgtgaagc ggctgaacgc caggaacttg aagccaaacg tcagcaggcc
    24421 attgaataca tcatatcttt aggtcttgat cccgaatcac tccttgctcc tgtaacagca
    24481 gatacagtaa aaaccaggcg gaaagccaaa ggcggagtaa gaaaggctaa ataccgcttt
    24541 aaggatgaaa atggcgagat cagagaatgg tctggtaatg gcaagcgtcc gcttgcttta
    24601 cagaagctgc ttgatgaggg gcatttcatg gaagatttcc tcattgagaa aactaagccg
    24661 gaacaggcag aatcgcctcg atggtataga tcacatacgg cactgttgca aatagtcggt
    24721 ggtgataaac ttatcatccc cttttgctga tggagctgca catgaaccca ttcaaaggcc
    24781 ggcattttca gcgtgacatc attctgtggg ccgtacgctg gtactgcaaa tacggcatca
    24841 gttaccgtga gctgcaggag atgctggctg aacgcggagt gaatgtcgat cactccacga
    24901 tttaccgctg ggttcagcgt tatgcgcctg aaatggaaaa acggctgcgc tggtactggc
    24961 gtaacccttc cgatctttgc ccgtggcaca tggatgaaac ctacgtgaag gtcaatggcc
    25021 gctgggcgta tctgtaccgg gccgtcgaca gccggggccg cactgtcgat ttttatctct
    25081 cctcccgtcg taacagcaaa gctgcatacc ggtttctggg taaaatcctc aacaacgtga
    25141 agaagtggca gatcccgcga ttcatcaaca cggataaagc gcccgcctat ggtcgcgcgc
    25201 ttgctctgct caaacgcgaa ggccggtgcc cgtctgacgt tgaacaccga cagattaagt
    25261 accggaacaa cgtgattgaa tgcgatcatg gcaaactgaa acggataatc ggcgccacgc
    25321 tgggatttaa atccatgaag acggcttacg ccaccatcaa aggtattgag gtgatgcgtg
    25381 cactacgcaa aggccaggcc tcagcatttt attatggtga tcccctgggc gaaatgcgcc
    25441 tggtaagcag agtttttgaa atgtaaggcc tttgaataag acaaaaggct gcctcatcgc
    25501 taactcaaag cgcaacaaac attktttacg tttgtgtaac atacctatgt acagtgccag
    25561 atggcgttgc tacgtgaaaa ataacctacc ctacccctgc ttttttcgca gattttacgt
    25621 agcacaccgt tgctatagca ttcatctaaa aagctgaatg tccttttctg tcgctgttgc
    25681 attttaattc actgaaaaat attgagtaat gaaaatgccg gtaacgcgtc aagctgttgg
    25741 ccaacgcgac aggcagtatt ggaagcaaca aaaaaaatga aagaaaaatc cctcaaatga
    25801 aggagaaaaa acggaactac agccgaacga caggcacaaa aaaacccgac tggtaatcgg
    25861 gcttttttgc gttttccagt cttgagttgg tggctctgac cggagaaggt tactctacac
    25921 ctaacgttta cattttattc actatggtgc tgtaaagcaa ctaaatgtgg ttaaggaacc
    25981 acatttagtg gtgtaacggg tgttttgtgt agcgtataat cagtcagtta gtcatgtagt
    26041 tggcttgcaa tcctgctgtt cccgtatctg cgggtatgaa cgattttaaa gtcctggctg
    26101 gataaacagg tggtgctgta ttcggtgctc tggcaggagg aggtcactct acacctaaca
    26161 atgcgagaga gccgttgtga caggcagtgt atgagyaagc aacggtgatt tcctccagtk
    26221 wtactggaga arcggatgat taatmtgtta atcatcgttc tcagagctgt rgtcgccgtt
    26281 gcaaacgcgc tgattgcagt tctggaactg atccgccaat tcatcgattg atgacaacgg
    26341 aaacgtaact aagggcagga agtgaaccgc ttcctgccct ttaacaaaaa aggaggattt
    26401 atggatttta tgagcatttt ggggcgctgt ttacttcttc ctttccctgt tgcgatgttt
    26461 gtcggttgcc tgtttcctgg catcgatgat cgcttatccg gaatgcttat gagtgttgct
    26521 gtgggatgtt tatcgtggta tgtcaccaga ccgaagaacc gacagacaaa ggccgcgtaa
    26581 gtggccttta attgggatac cctttagtta caacattcta atagctcatt ccatcctccg
    26641 ctcatccagc aaacataacc tccctgcccc tccccactac agaaagtggc gcgccccgcc
    26701 cgtacgggcg gaatctaatc gcttaatttt gaatgttgta actaaacata ctcattgctg
    26761 tattgccaca aggtttcgca gcaagggagg ataccgaaag taacgctgtc acttttgctt
    26821 tcaagtgacc aaccaacggg tacatcacac tgacatacaa taatgtattt cttcatgatg
    26881 tacatcattg taattcattg tgacatacac tatagtatgt ccatgtgaca tacgcatgcg
    26941 tacatcacat agaaatacac atgagtaaat cactgtgaca tacaaggggt actatgatta
    27001 tcgtaatcgg tggtgataaa ggcggtacag gtaaatcaca tctggcaacc aacttaactg
    27061 tttgcctctc acaacaggga aagagaacgg ggcttgttga aacagacctg aatggctcga
    27121 ccaaaaaatg gaataaacgc agagaacagg ccggattacc gcccgtcgca ttaaatgaag
    27181 cctatggcga catcagtgcc aaaataacaa aaatggcaga tgtagcagaa atcctcatta
    27241 tagatactgc cggatatgac agcacggagt tcagaactgc actaaaagtt gcagacattg
    27301 tgattgtccc gatcgacccg cttgcccagg tggaagcaga cagtcttcag actgtgacaa
    27361 aaattgtcag ggatgcgcaa aaaataaatc ccaggctggc tgcacatgtg ctcctgtata
    27421 aatgccagcc aaatacgttc agtgaacaac aagaattaag agactctctc aacagccatg
    27481 attactggct taaaccaatg aaaagcacgg tttcttttct ccgggccttt gtaagagcaa
    27541 tgaatcaggg aatgggggtt cacgagttaa aaagtaatgt tagcggtgcc agccaggcaa
    27601 aagcacaaat cgaactcttg ctgaaagaac tggaactgta aatcatagtg acatacacta
    27661 atgtacatca tcatgatata cattagtgtg aaacaatcag attagaaggt acatcatggc
    27721 aaagctggaa ctaccagaac tagaacaaaa ccaggaagtg aacgccacaa aatttgttca
    27781 ggacgcagga aaacgcccca cagagaacaa aacaaaactg gcttcattcc gcataccgaa
    27841 tgaattgctt gaattcattg ataacgaatc aaaaagactg catcgtccca agacaaaaat
    27901 aatcaaagca gcattactgg cttatcagga tctggacgaa aacgaactca ttaatttgtg
    27961 gttcagagct gacagaaatg attaatcata gcaagtggcc caataaactc tttatcattt
    28021 tcttttagat acttatctga atgtactaac ttcatcactt ttaaatgtag ttgtgattca
    28081 tttttagtta ctcttgcaat aaaataccct tgtacagttg ttgcacgggt atttaggagc
    28141 actagatgag ccttatcgat ttaagtttat caggattatc agaaccagga acaaaactta
    28201 ttgaaaaaat aagtgatgct attggtgtgc tttatgaacc tacaagaatc aggaaaaaag
    28261 cgaaggctga agctgaagct aaacgcacag agctaatttc taggttagag cttgagggaa
    28321 tagaaaaacg ggcagttgag cgttttctca aacgtgaaac gaaacgacag gaaaacattg
    28381 aaaatataac aatgcaagca gcacaaagtc tatctgagag tgataatgtt tctgatattg
    28441 acgaagattg gatagaggct ttcttcaggg agtgtgagga tattagtgac gaacaaatgc
    28501 aaatgctttg gggaagaatt ttatccgaag aagcaaagtc aaaaggttcg tttagtcgta
    28561 gaaccttaaa actattatcc actataagca aagaagaagc gaaccttatt acttattttg
    28621 gaaagtttgt ttggcaggca aacaaactca ctccaatttt atttaccgat gagaatggag
    28681 atactgaagg tataactttc gataaacttt cggttttaga ctccttaggc gttattcaac
    28741 aaggcattgg ttatagttta caaattataa atactctcaa gtgtatattc agtatgggat
    28801 tgcgcaatga ttgcctaata aaatttctga aatatttctg tatcgcataa ttttttatat
    28861 cagataaatt gtactggatt tcttaaaaaa ttgcagtata attgccgcaa ttatcccacc
    28921 gtttattttt tgagtagttt ctcatgatgc agcatacttc tgtgtggtac cgacgctcgg
    28981 tcagtccgtt tgttcttgtg gcgagtgttg ccgttttctt gaccgcgacc gccaatctta
    29041 ccttttttga taaaatcagc caaacctatc ccatcgcgga caatctcggc tttgtgctga
    29101 cgatcgctgt cgtgctcttt ggcgcgatgc tactgatcac cacgctgtta tcatcgtatc
    29161 gctatgtgct aaagcctgtg ttgattttgc tattaatcat gggcgcggtg accagttatt
    29221 ttactgacac ttatggcacg gtctatgata cgaccatgct ccaaaatgcc ctacagaccg
    29281 accaagccga gaccaaggat ctattaaacg cagcgtttat catgcgtatc attggtttgg
    29341 gtgtgctacc aagtttgctt gtggcttttg ttaaggtgga ttatccgact tggggcaagg
    29401 gtttgatgcg ccgattgggc ttgatcgtgg caagtcttgc gctgatttta ctgcctgtgg
    29461 tggcgttcag cagtcattat gccagtttct ttcgcgtgca taagccgctg cgtagctatg
    29521 tcaatccgat catgccaatc tactcggtgg gtaagcttgc cagtattgag tataaaaaag
    29581 ccagtgcgcc aaaagatacc atttatcacg ccaaagacgc ggtacaagca accaagcctg
    29641 atatgcgtaa gccacgccta gtggtgttcg tcgtcggtga gacggcacgc gccgatcatg
    29701 tcagcttcaa tggctatgag cgcgatactt tcccacagct tgccaagatc gatggcgtga
    29761 ccaattttag caatgtcaca tcgtgcggca catcgacggc gtattctgtg ccgtgtatgt
    29821 tcagctatct gggcgcggat gagtatgatg tcgataccgc caaataccaa gaaaatgtgc
    29881 tggatacgct ggatcgcttg ggcgtaagta tcttgtggcg tgataataat tcggactcaa
    29941 aaggcgtgat ggataagctg ccaaaagcgc aatttgccga ttataaatcc gcgaccaaca
    30001 acgccatctg caacaccaat ccttataacg aatgccgcga tgtcggtatg ctcgttggct
    30061 tagatgactt tgtcgctgcc aataacggca aagatatgct gatcatgctg caccaaatgg
    30121 gcaatcacgg gcctgcgtat tttaagcgat atgatgaaaa gtttgccaaa ttcacgccag
    30181 tgtgtgaagg taatgagctt gccaagtgcg aacatcagtc cttgatcaat gcttatgaca
    30241 atgccttgct tgccaccgat gatttcatcg ctcaaagtat ccagtggctg cagacgcaca
    30301 gcaatgccta tgatgtctca atgctgtatg tcagcgatca tggcgaaagt ctgggtgaga
    30361 acggtgtcta tctacatggt atgccaaatg cctttgcacc aaaagaacag cgcagtgtgc
    30421 ctgcattttt ctggacggat aagcaaactg gcatcacgcc aatggcaacc gataccgtcc
    30481 tgacccatga cgcgatcacg ccgacattat taaagctgtt tgatgtcacc gcggacaaag
    30541 tcaaagaccg caccgcattc atccgctgat ttctccctgt attttttcca aacccaccgc
    30601 acactccatt cgtattatgg gcggtggggt ggggtttgtt atgccgtatt tatcaaataa
    30661 acgcctactt gctgagatga gtatcgctct tgtcatggcg atcgttgcca cgctgaccct
    30721 tgagcacagt cagattgatc tgatggtcgc tgattggttt tatctgggta tggggcattg
    30781 gatggttgcc aagcaagctt ttttgccaga tttgctactg tattctggac taaaaaagct
    30841 gctgatggcg atgctgatct acttgctggt tgcgaccatt tgccgtgctt atcatgaaaa
    30901 aagggcaatg ctatcactgc caagtggctt gtcccagtga caaaatttcg cgtgcgtgag
    30961 cttgcgtatc tggtgctgac tttgatccta gtgccgacag ttgtcgcgtc attgaaggca
    31021 tatactcatg tggtctgccc tgtgcatttg acgatttttg atggtacgct gccgtatttg
    31081 ccgatgcttg atagtatgcg taacaccatt cctgataagt gctttcctgc ggcgcatgcc
    31141 agtagcggat ttgcgctgtt tgcctttgcg tttgcgccaa gtttgcgccg ccgtcgtggt
    31201 gcgatcatca tcgtggtgat ggcattgggc tgggcgatgg gctgctataa gatgattatt
    31261 ggcgatcatt ttttgagcca tacggtggtg tcgatgatgc ttgcgtgggc gatgtcggca
    31321 gggcttgcgt gggtgttttt taagaagggt gaacaagttt aatcgccttt aaaagtaaaa
    31381 acggtcgtat cggttattac ggaacggttt tttcagttga gtttcaaagc gatgattcat
    31441 caacctggaa actaccaata ggaacggctt tacttacgcc tatcggtcaa gaattgatga
    31501 aaatatgcgg ttccactcca gatattgcgt atttaaataa attcctcaac aaaataaatg
    31561 ttgaaggaag ccaggtaaaa ctatcaatta ttaatatgta aagaggtcga gttacctgtc
    31621 tgagttccac taaccataat taaaagcgac cgcaaaaact gcccagtgaa aactgtgttg
    31681 ccagtaatca caaatgcagc aagtactaat aaagagcctg ttaagcccgc aaatatgtgg
    31741 gcttattttt aattactctt catcatcccg caggaactga caaaaatctt cgctccccat
    31801 catatcgaca gtgtttttaa attcgaaaaa agaaattcct gtcatagcac acacgcgctg
    31861 gataatcagt tttttctttt gctgtctgac ggttgcggtt tcaccaaact ggataacagc
    31921 caggactgtt tcatcatatg atttcaggac aaaatcacag gttatattct gcacttcacg
    31981 gattaaatct tttacagctt cctcgctacc atgaggacga acaaattcaa tgagccgtat
    32041 tttgggaaaa acggaataat caggtataat attacgtgaa agaatgccta aaaactctga
    32101 ttcattattt gagagtaagg gtactttagt aaaacaatca acctccccaa tggctgtaaa
    32161 agcattggtt gtcaaagctg gattattctt aataaaatca gagaatacat tttcagctga
    32221 tggcaaaaca acagcagaat tatgttgttc atctcgtttt ttattacggt taaatatcat
    32281 ttcatattcc ttttaaaaga gcctgcggca ggcacaggca aaaacatcgt ttttggacaa
    32341 tctgattcaa atgttaacat ttgacatcgg attgtctatc ctgcattgtt ctttactgtc
    32401 tgtaagatcg gcgctcattc ttccggcgtt ctcccgatac caaaaagacg gaacgcaaaa
    32461 cggctttcga tccaccattc aaaaatctgc tctgcgcaac cacaaacagt taaggcgatc
    32521 catgcagcaa gaacaacgta actactgaca tctgcaccca tgtaccaggc gatagttaaa
    32581 cccatcactg cgataccgcc taaaaactgc aacaagaaac gaaatcccgc aagaatcccc
    32641 aatggaataa caacaaccag ataaagggaa gcagccagaa ggtatctgac aggtgtcagc
    32701 agataaaaga acctggatat tttctttttg tcagaataaa cggcatcatt tgcaacatcg
    32761 gttgaatgat cattcatgct gtccctgatt ctttgaaaat ctacgatatt atccttcata
    32821 ttgttatgac ctcaattttc aggtgggtac attttatcaa acatattagt aaactctgag
    32881 tcttccctgg tatcgccctc ataaccaatt gtataagaga actttaattt ataaactttt
    32941 ctcccaattt tttctgaaac tacgaaactt aagttcttta cttccgtatg tttcatgatt
    33001 tcttttactg atttattaag aacatctctt ttaaaagcag gataatctgg atacttataa
    33061 tccttcaccc cccccgcccc tattgtataa agattcaatt catctttaag ttcatctatt
    33121 gtcatttcaa aactattcgc gcgagaatta ttactatata ttttacgaat gagttgatat
    33181 agtgatgcag cattaacact tgtcagtcga acaacagata ataaaacttg cgttgtataa
    33241 cgtttttctt caccaataag tttacataaa aatcttttcg cttctttcgt aaacttgatc
    33301 cccactctac cttcattcct gtaataagta gaaaaaacag tcagactcaa attcattgaa
    33361 tcaggtacat tacttttagt gaacttaaat cccaaatcac tactcagttc taatatttca
    33421 tcatgtttca gcttaagaag cgtcgtatct aatatattag agccatccct caaagcaaga
    33481 taagccgcat caggcttaac ctgaacccat ttaatgtaat cggcaactgt cacataaaat
    33541 atgtgatcat catcgaattc atttttagag tttatctggc acatggctaa aaataagact
    33601 tttttagcag ccataggcaa tgttgacagc gttgaattca attcatttcg atgtctcact
    33661 tttgttaagc gagaaaggga agtcttattt gtcgtcattc tcattgttcc aacactcttg
    33721 ataatcagac tttaacacca gaaacatgat attacaacac aatcaatatc atgtttaacc
    33781 gagtatcttc tcatgtttca tatctgtgat ttatctcaca aaggtaatcc atgctcaaaa
    33841 tccacactgg attcaaggca gattaacaac agattcaaaa tagattcacc agaaagaaca
    33901 acgaattagt attcttatga cacattttgt ggatatcacc gaggaagctc tcatgtttaa
    33961 ccgaggaagc tctcatgttt aaccgaggaa gctctcatgt ttaaccgagg aagctctcat
    34021 gtttaaccga ggaagttatc atgtttaacc gaggaagctc tcatgtttag acaaaaaaca
    34081 cgcttaaaat caataaatta gagctactct aagtttttaa gtttttaaga aaaacaagaa
    34141 aagataaggc ttttaatgcg tgcgaatatt caggaactgt ggataactca acaaaaccag
    34201 caacgatgat ggttccttac cataaatctg tcccccgatg attattaccc gcaagctaaa
    34261 acaaacatca tcaatcatta aaactcataa ctttcaataa cataaaatca tcaaaaaaat
    34321 atttgatgcc ttatgtatct caattttcaa gaccataaat ttgtccctag ttaactttaa
    34381 cttattgaaa taaatataat attcgtgcgt actgatccta atgtcacatc gcaaaaattc
    34441 cgcttcctcg ctcactcagt cgctacgctc ctgccgttcg gctgcggcga gcggtatctc
    34501 ctttctcaaa accagagaga ttcagatcat atgatccgtt atttgatcct ttttggatct
    34561 tccactaaga agccctgaat cgcgctctgc cgcttcgttc gatacaacca tgaggaaaac
    34621 catgcgaaat gaaaaaaatc gcttaaaatg cgattcagag cgttttaggg aggttctgtt
    34681 agttctcctg cattgcgccc gtagttcgct aacgctcaca cgcgcagtac agcgccccgc
    34741 catgctgcaa tgcaccaggg cggggtaaac tcgcttgcgc tcgcgctaac tgcggcattc
    34801 tgcggcgcaa atcagcataa tcatggcctg ctggtcagtt gggctttgca gggtgaaggg
    34861 atggcctgtg caccctggta cgttcgtcag cggctgcgcc gcgcttcggg gcgatgtggc
    34921 tcctgtgctg ccctggtatt ttcgttcgcc ccttccatcc gcttacgcgg attaa
//
