LOCUS       NZ_KU644676             7637 bp    DNA     circular CON 15-MAY-2024
DEFINITION  Aeromonas allosaccharophila isolate HP5 plasmid pHP5, complete
            sequence.
ACCESSION   NZ_KU644676
VERSION     NZ_KU644676.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14227255
KEYWORDS    RefSeq.
SOURCE      Aeromonas allosaccharophila
  ORGANISM  Aeromonas allosaccharophila
            Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
            Aeromonadaceae; Aeromonas.
REFERENCE   1  (bases 1 to 7637)
  AUTHORS   Wen,Y., Pu,X., Zheng,W. and Hu,G.
  TITLE     High Prevalence of Plasmid-Mediated Quinolone Resistance and IncQ
            Plasmids Carrying qnrS2 Gene in Bacteria from Rivers near Hospitals
            and Aquaculture in China
  JOURNAL   PLoS One 11 (7), e0159418 (2016)
   PUBMED   27427763
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7637)
  AUTHORS   Wen,Y., Pu,X., Zheng,W. and Hu,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2016) Hangzhou Center for Disease Control and
            Prevention, Microbiology Laboratory, Mingshi Road, Hangzhou,
            Zhejiang 310021, China
COMMENT     ##Assembly-Data-START##
            Sequencing Technology        :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Name              :: GCF_009968165.1-RS_2024_05_15
            Annotation Date              :: 05/15/2024 01:38:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.7
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 9
            CDSs (total)                 :: 9
            Genes (coding)               :: 9
            CDSs (with protein)          :: 9
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KU644676.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7637
                     /organism="Aeromonas allosaccharophila"
                     /mol_type="genomic DNA"
                     /isolate="HP5"
                     /db_xref="taxon:656"
                     /plasmid="pHP5"
                     /geo_loc_name="China"
     gene            complement(339..806)
                     /locus_tag="HTH04_RS00005"
     CDS             complement(339..806)
                     /locus_tag="HTH04_RS00005"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012954630.1"
                     /translation="MQFKRQGRRVQVLAYRGYDKEKRRAIVKMMGSIDVYSYEPSGGLI
                     ENLTDEEKTELQSYIETERQAAEKRSRVYYAKSAASRIVEVADTIKAGDFEPSEAWAAD
                     TWAAIEALTKAMRKAGYPKLRKAPQKAADAPMPGQAGLPFGDAPETPESAS"
                     /name="hypothetical protein"
     gene            1264..1695
                     /locus_tag="HTH04_RS00010"
     CDS             1264..1695
                     /locus_tag="HTH04_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004171598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_012537712.1"
                     /translation="MNTDESKRRRRGPAPLDATDKRGHTVSVRLNDAELARLDSQRDAV
                     QMQRGEYLRAAALHRLPPTIPAANREQWAELARTAANLNQIARHLNEGQRGDGERIGKA
                     LGLQLSAELANCLRLLVLVRGDLIGVKHDSEDVEDESEG"
                     /name="plasmid mobilization relaxosome protein MobC"
     gene            complement(1886..2242)
                     /locus_tag="HTH04_RS00055"
     CDS             complement(1886..2242)
                     /locus_tag="HTH04_RS00055"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_043849886.1"
                     /translation="MQTLARRFVARSHGHVDLLVGQLPALGPRIAQPRRQGQAVGMLKL
                     LGRLDGAAGFPLAQPNFPVQPYPAGHDVDVILVRVLVAHCHPRRIGLVKAHALHEVSRH
                     GFPLLGAQALTGRQ"
                     /name="hypothetical protein"
     gene            2451..3134
                     /locus_tag="HTH04_RS00045"
     CDS             2451..3134
                     /locus_tag="HTH04_RS00045"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_043849885.1"
                     /translation="MTKLETVRALNDSGPQLQIVESVRTLQQSLSLMHEDLKRLPVAVS
                     TETAQTLEPLARLQQDVTQVLEAYDKVTAIQRKTLDELTQQMSASAAKAFEQKAGELDK
                     TISDLSNSLSGLETSISSMKQTAEQVADLPGNLVSAQKDMTQAANKLTEAANETRPRLW
                     RQALGLILAGAVGAMLVATGQVALNRLVPPSDVQQTADWANAIWNKATPKERELLEQIV
                     NRPAN"
                     /name="hypothetical protein"
     gene            3170..4120
                     /locus_tag="HTH04_RS00050"
     CDS             3170..4120
                     /locus_tag="HTH04_RS00050"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_043849884.1"
                     /translation="MKREGRHLSVKAGGDEAYRVTRQQDGRWLWCDRYGNDGGDNIDLV
                     REIEPGTGYAEAVYRLSGAPTVRQQPRPSEPKRQPPQLPAQGLAAREHGRDYLKGRGIS
                     PDTIEHAEKAGMVRYADGGVLFVGYDRTGTAQNATRRAIAPADPVQKRDLRGSDKIYPP
                     ILPGDPAKVWIVEGGPDALALHDIAKRSGQQPPTVIVSGGANVRSFLERDDVQAILKRA
                     ERVTVAGENEKNPEAQAKADAGHQKQAQRVAEITGREVRQWTPKPEHGKDLADMNARQV
                     AEIERKRQAEIEAERARNRELSRKSRGYDGPSFGR"
                     /name="hypothetical protein"
     gene            4191..5054
                     /locus_tag="HTH04_RS00020"
     CDS             4191..5054
                     /locus_tag="HTH04_RS00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014003865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="WP_012537710.1"
                     /translation="MAINIMEAFQQEPPQLDFIWPGFLAGTVGALVAPGATGKSFWALE
                     AAMSIACSVAGGDVVNLKPQHTGRVVYLAGEDPEPALIRRVHAIGQHLNQSAREAIAEN
                     LTLEPIMGKRLNVMDEEHLRRVIEYSAGARLIVLDTLSRIHSLDENSNGDMARLVATLE
                     HVAASTGASVLYLHHVSKGSAREGQTDQQQAARGASALIDNARWCGFVAKMTEDEAKRL
                     SDRAYDRQPIGNDRRGFFVRFGVSKQNYDATPLDQWYERRDGGVLVPVELLEVPNGKKG
                     GSREQA"
                     /name="helicase RepA family protein"
     gene            5041..5922
                     /gene="repC"
                     /locus_tag="HTH04_RS00025"
     CDS             5041..5922
                     /gene="repC"
                     /locus_tag="HTH04_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014003864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein C, IncQ-type"
                     /protein_id="WP_012954629.1"
                     /translation="MSKHDLTHARHDPAHCLAPGLFRSLKRGERKRGKLDVVHDYGDGK
                     RIEFSGPEPLGADDLRILQGLVAMAGPGGLVLSPEPQTEAGQQLRLFLEPKWEAFQQDA
                     MVVKGSYRALAREIGYANPDDTKPVRECIERLWKVSIIAQNGRKRQGFRLLSEYASDEQ
                     DGKLYVALNPLIARAVMGGAQHVRIDMDEVRALQTDPARLMHQRLCGWIDPGKSGRVEL
                     DTLCGYVWPGQATNPNTLKTRRQAARRALPELAALGWAVSEYAKNKFEIGRPKATHLLG
                     PAPKTQEISHEK"
                     /name="repC"
     gene            5912..6163
                     /locus_tag="HTH04_RS00030"
     CDS             5912..6163
                     /locus_tag="HTH04_RS00030"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_064163397.1"
                     /translation="MRNDWETPPTVEVRIPVKLNSDSGICEHHFRKVCGQGFFEQKLGF
                     EGRHLFDSLNKPAAKRSAAVVDPRRWNRTVHLTSEYVL"
                     /name="hypothetical protein"
     gene            complement(6466..7122)
                     /locus_tag="HTH04_RS00035"
     CDS             complement(6466..7122)
                     /locus_tag="HTH04_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrS2"
                     /protein_id="WP_012537714.1"
                     /translation="METYRHTYRHHSFSHQDLSDITFTACTFIRCDFRRANLRDATFIN
                     CKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIELRECDLKGANFSRANF
                     ANQVSNRMYFCSAFITGCNLSYANMERVCLEKCELFENRWIGTHLAGASLKESDLSRGV
                     FSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIASWQQEQLLEALGIVVFPD"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrS2"
     ARG             complement(6470..7122)
                     /name="qnrS2"
                     /gene="qnrS2"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrS2"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          4192..5054
                     /name="IncQ2"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.495"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1680..4117
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.401"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ccccctgttt aactccaccc aacccccacg gtaactccac ccaaccccca cggtaactcc
       61 acccaacccc cacggtaact ccacccgccc cgatctggaa aacccagacg gggcgcggat
      121 ttgctggcga ttcgcaaaat ccatccaaga ttctctaaga atctccacta ggcgcagcac
      181 agcccgcgcc ccttcggcgc ggtctggcat tgcctcaaat gcccggccaa gaccatgcgc
      241 aaggcgaaca cctctccccc cgccttcggc gaccccctcc gggggtaaag ggccagcggg
      301 gagagggggg ggggtgccgg tttcccggcc taaacccctc aggaggcgct ttctggcgtt
      361 tctggcgcat ccccaaaggg caaccccgcc tgacccggca tcggcgcgtc tgcggctttc
      421 tggggcgctt tgcggagctt cgggtagccc gccttgcgca tggccttggt cagcgcctcg
      481 attgccgccc aggtatccgc cgcccatgcc tcggacggct caaagtcccc ggccttgatc
      541 gtgtcggcaa cctcaacaat acgactggcg gcagacttag cgtaatacac tcggcttctc
      601 ttttctgctg cctgtcgttc tgtttcgatg tatgactgta gttctgtttt ttcttcgtct
      661 gtcagattct caattaggcc gcctgacggc tcgtaagaat atacgtcaat agaccccatc
      721 atcttgacga tggcgcggcg tttttccttg tcataccccc ggtaggcgag cacctgaacc
      781 cggcgacctt ggcgcttaaa ctgcatggcg gtttctccgt ttgactgtgt gattatatta
      841 tagttcgaca gtcgcacgct gtcgagtgtt tattgtcggc ctatttttca atccgaccgt
      901 cgcactcaaa taggtttgca ctgtcggatt gagtaacgct cgacagtctg ccgttcttgc
      961 gataccatag ttgcattgta tcagttcgcc ccggcgcctt gcccaccccc tctccccgct
     1021 ggcccattac cgcccttggg cggtcgggcc gagagcgcag cgagcgggcc gggtgggtgg
     1081 ctgttcggtg cttgcatgga gatgtgctat tatggtattt gcgcggtggt ttggcatgga
     1141 gcaaggtgta acctacgctt cgcttggttc tcaccctccg gccttcggcc tacgcccccg
     1201 ctcccttcgg tcggggggtt gctgcgcgtt tcgcttcgct tcacttactg gagggcttcg
     1261 cccatgaaca ctgacgaatc caagcgccgc cgccgtgggc ctgcgccgct cgacgccacg
     1321 gacaagcgcg ggcataccgt ttcggtgcgc ctcaacgatg ccgagcttgc gcggctggat
     1381 tcgcagcgtg acgcggtgca gatgcagcgg ggcgagtacc tacgcgccgc cgctctgcat
     1441 cgcctgccgc ccaccatccc ggcagcgaac cgggaacagt gggcagagtt ggcccgcaca
     1501 gcggccaacc tgaaccagat cgcccggcac ctgaacgaag ggcagcgggg cgacggggag
     1561 cgcatcggca aggcgctggg cttgcagttg agcgccgagc ttgccaactg cctgcgattg
     1621 ctggttctgg tgcgcggcga cttgataggc gtcaagcacg actcggagga cgtggaagat
     1681 gaaagcgaag gttagccgtg gtggcggttt tcgcggtgcg ctgaactacg tttttgacgt
     1741 tggcaaggaa gccacgcaca cgaaaaacgc ggaacgtgtc ggcggcaaca tggccgggaa
     1801 tgacccccgc gaactgtcgc gggagttctc agccgtgcgc cagttgcgcc cggacatcgg
     1861 caagcccgtc tggcattgct cgctgtcact gcctcccggt gagcgcctga gcgccgagaa
     1921 gtgggaagcc gtgacgactg acttcatgca gcgcatgggc tttgaccaga ccaatacgcc
     1981 gtgggtggca gtgcgccacc aggacacgga caaggatcac atccacatcg tggccagccg
     2041 ggtagggctg gacgggaaag tttggctggg ccagtgggaa gcccgcagcg ccatcgaggc
     2101 gacccaagag cttgagcata cccacggcct gaccctgacg ccggggctgg gcgatgcgcg
     2161 ggccgagcgc cggaagctga ccgacaagga gatcaacatg gccgtgagaa cgggcgacga
     2221 accgccgcgc cagcgtctgc aacggctgct ggatgaggca gtgaaggaca agccgaccgc
     2281 gccagaactg gccgaccggc tacatgccgc aggcgtaggc gtccgggcaa acctcgccag
     2341 caccgggcgc atgaacggct tttccttcga ggtggccgga gtgccgttca agggcagcga
     2401 cttgggcaag ggctacacat gggcgggact acagaaatca ggggtgactt atgacgaagc
     2461 tagagaccgt gcgggccttg aacgattcag gcccacagtt gcagatcgtg gagagcgtca
     2521 ggacgttgca gcagtccctg agcctgatgc acgaggactt gaagcgccta ccggtcgcag
     2581 tctcgaccga gacggcgcag accttggaac cgctggcccg actccaacag gacgtgacgc
     2641 aggttctgga agcctacgac aaggtgacgg ccattcagcg caagacgctg gacgagctga
     2701 cgcagcagat gagcgcgagc gcggcgaagg cgttcgagca gaaggccggg gagctggaca
     2761 agaccatctc cgacctgtcc aacagcctgt cagggctgga aacgagcatc agcagcatga
     2821 agcagaccgc ggagcaggtg gcggacttgc cgggcaatct ggtgagcgca cagaaggaca
     2881 tgacgcaagc cgccaacaaa ctgaccgagg cagcgaacga gacgcgcccg cgcctttggc
     2941 ggcaggcgct ggggctgatt ctggccgggg ccgtgggcgc gatgctggta gcgactgggc
     3001 aagtcgcttt aaacaggcta gtgccgccaa gcgacgtgca gcagacggcg gattgggcca
     3061 acgcgatttg gaacaaggcc acgcccaagg agcgcgagtt gctggaacag atcgtcaatc
     3121 ggcccgcgaa ctagatccga ccgcctacct tgaggcgagc ggctacaccg tgaagcgcga
     3181 agggcgacac ctgtccgtca aggctggcgg tgatgaggcg taccgcgtga cccggcagca
     3241 ggacgggcgc tggctctggt gcgaccgcta cggcaacgac ggcggggaca atatcgacct
     3301 tgtgcgcgag atcgaacctg gcaccggcta cgccgaggcc gtctatcggc tttcaggtgc
     3361 gccgacagtc cggcagcaac cgcgcccgag cgagccgaaa cgccaaccgc cgcagctacc
     3421 ggcgcaaggg ctggcagccc gcgagcatgg ccgcgactac ctcaagggcc ggggcatcag
     3481 cccggacacc atcgagcacg ccgagaaggc gggcatggtg cgctatgcag acggtggcgt
     3541 gctgttcgtc ggctacgacc gtacaggcac cgcgcagaac gccacacgcc gcgccattgc
     3601 ccccgctgat ccggtgcaga agcgcgactt acgcggcagc gacaagatct atccgccgat
     3661 cctgccgggc gacccggcaa aggtctggat cgtggaaggt ggcccggatg cgctagccct
     3721 gcacgacatc gccaagcgca gcggccagca gccgcccacc gtcatcgtgt caggcggcgc
     3781 gaacgtgcgc agcttcttgg agcgtgacga cgtgcaagcg atcctgaagc gggccgagcg
     3841 cgtcactgtg gccggggaaa acgaaaagaa ccccgaggcg caggccaagg ccgacgccgg
     3901 gcaccagaaa caggcgcagc gggtggccga aatcaccggg cgcgaggtgc gccaatggac
     3961 gccgaagccc gagcatggca aagacttggc cgacatgaac gcccggcagg tggcagagat
     4021 cgagcgcaag cgacaggccg agatcgaggc tgagagagcg cgaaatcgag agctttcacg
     4081 caagagccgg gggtatgatg gccccagctt cggcagataa gagcgcctgt cagtcggtgt
     4141 gatgaaccga ccgacaggct aaccatcatc aacctgagta ggaggccgat atggctatca
     4201 acattatgga ggcgttccag caggaaccgc cacaactgga cttcatctgg cccggctttc
     4261 tggctggcac cgtgggcgca ctggtggccc ccggcgcgac cggcaagagc ttctgggcgc
     4321 tggaagcggc tatgtccatc gcttgcagcg tggcaggcgg tgacgtggtg aacctcaagc
     4381 cgcagcacac cgggcgcgtg gtctatctgg ccggtgaaga tcccgaaccc gccctgatcc
     4441 ggcgcgttca cgccatcggc cagcacctca accagtcagc ccgcgaagcc atcgccgaga
     4501 acctgaccct tgagccgatc atgggcaagc gcctgaacgt catggacgag gagcacttgc
     4561 gccgcgtcat cgagtacagc gccggggcgc ggctgatcgt gctggacacc ctgagccgga
     4621 ttcacagcct cgacgagaac agcaacggcg acatggcgcg gcttgtcgcc acgctggaac
     4681 acgtcgcggc cagcactggc gcgtctgtcc tgtacctgca ccacgtcagc aagggcagcg
     4741 cccgcgaggg gcaaaccgac cagcagcagg cagcgcgggg cgcatcggca ctgatcgaca
     4801 acgcccgctg gtgcggcttc gtcgccaaga tgaccgagga cgaggccaag cgcctgagcg
     4861 accgcgccta tgaccgtcag cccatcggca acgaccggcg cggcttcttc gtgcgcttcg
     4921 gcgtgagcaa acagaactac gacgccaccc cgcttgacca gtggtatgag cgccgagacg
     4981 gcggcgtgct ggttccggtg gaactgctgg aagtgccgaa cggcaagaag gggggcagcc
     5041 gtgagcaagc atgacctgac ccacgcccgg cacgacccgg cgcattgtct ggcccccggc
     5101 ctattccgca gcctcaagcg tggcgagcgc aagcgcggca agctggacgt ggtgcatgac
     5161 tatggcgacg gtaagcgcat cgagttcagc ggcccggagc cgctgggcgc tgatgacttg
     5221 cgcatcctgc aaggacttgt ggcaatggct gggccgggtg gccttgtgct gtcacctgag
     5281 ccgcagaccg aggccgggca gcaactccgg ctgttccttg agccgaaatg ggaagccttc
     5341 cagcaggatg cgatggtggt caagggcagc tatcgagcac ttgcccgcga aattggctac
     5401 gccaaccccg acgacactaa gccggttcgg gagtgcatcg agcggctttg gaaggtgtcc
     5461 atcatcgccc agaacggcag gaagcggcag ggcttccgcc tgctgtccga gtacgccagc
     5521 gacgagcagg acggaaagct gtatgtagcc ttgaatcccc tgattgctcg cgccgtcatg
     5581 ggtggcgcgc agcatgtccg catcgacatg gacgaggtgc gggcgctaca gaccgacccg
     5641 gcgcggctga tgcaccagcg cctatgcggc tggatcgacc ccggcaagtc cgggcgggtg
     5701 gaactggaca cgctttgcgg ctacgtctgg ccggggcagg caaccaaccc caatacgctc
     5761 aagacgcgac gccaagcggc tcgcagggcg cttcctgagc ttgccgcatt gggctgggca
     5821 gtcagcgaat acgcaaaaaa caagtttgaa atcggcaggc cgaaagcaac gcatctgctc
     5881 ggcccagcac ccaaaacaca ggaaattagc catgagaaat gattgggaaa cgccgccgac
     5941 agtcgaagtg cgtattccgg tgaagttgaa cagtgattcc ggaatctgtg aacaccattt
     6001 ccggaaagta tgcggacagg gattcttcga gcagaagctg ggctttgagg ggaggcatct
     6061 tttcgactca ctgaacaagc cagcagccaa gcgcagcgcg gcagttgtgg atccaagacg
     6121 ttggaacagg acggttcatc tgacatcaga gtacgtgctc tgaggtgttg taggagagga
     6181 ataaagtttc atactaagca gtcaagtaac cctgtttgta ccgttctaaa tgatactcac
     6241 ccagaaataa agattcatac taattcctac tacaaaatct gagtcacgct acaactgagt
     6301 aataaagtat catactggtt gtcttgagca tccacagatt gattggcccc attcaaacac
     6361 gtttctggac aagaatgagc tagaagtatt gatctagctc tggtgatttg aattagaaaa
     6421 tgtattaatg ttgtgtatag tttatcagca ggtattcgta agcatctagt caggaaaaac
     6481 aacaataccc aacgcttcga gaagctgttc ttgttgccag ctggcaattt tgatacctga
     6541 tgtatcgact tttcgaggat ctaaaccgtc gagttcggcg tgacataaat tagcaccctg
     6601 taggctaaac tgtccccaga catcttcaga aaaaacacct cgacttaagt ctgactcttt
     6661 cagtgatgcg cccgcgaggt gagtccctat ccagcgattt tcaaacagct cacatttttc
     6721 taaacagacc cgctccatat tggcataaga caggttacat ccagtaataa aggctgagca
     6781 aaagtacata cgattactca cttgattggc aaagtttgct cgggaaaagt tggccccttt
     6841 taaatcacac tcacgtaact caataccgta gcaattggcg ttactaaagt ttgccatcgc
     6901 aagctggcat tgttggaaac ttgcatcgcg aaggtctgcg acatcaaaat ggcaaccttc
     6961 gatatcaccc tgttcaatga acttgcagtt aataaatgtc gcatcacgca agttagcacg
     7021 tcgaaaatcg catcggataa aggtgcaagc agtgaaagta atatcactta gatcttgatg
     7081 tgaaaaactg tggtgtcgat atgtgtgacg gtaggtttcc atgttgactc ctatgatgaa
     7141 ctggacgcaa cactaccatc aaagccacat cacatcacca aaataaaaac actaaaaatc
     7201 aagatcttaa aaaccctcat tttgcctatt ttaagggggt aaaatagcgc cctgagcctc
     7261 tatgttaacg ttcaaagtac gcggcaccat tgaaaaaagt tatccgctta aaaagccaca
     7321 gagaaaagga acccaataga ttactgatgt ccgccattag gtaaagtaac cttaaacgga
     7381 agcctgcaat ttgaagtaga tacaaggtct aagaaggaat ggggcataaa cgttttagaa
     7441 atggcagtgt actctgatcg ctgccattta agtatgaatc tttaatactc agtatgattc
     7501 tttattactt agtaacgaaa ctttattcta ctcacacagg tgtccggaat cggtgtacac
     7561 gcaagccgga taacgtagcc attgagccgg aaaccggcga gcactggggc agcgtgatct
     7621 ggtgcgagta tgtgtga
//
