LOCUS       NZ_KT896500             7748 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Klebsiella pneumoniae strain I70 plasmid pKPSH70, complete sequence.
ACCESSION   NZ_KT896500
VERSION     NZ_KT896500.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14226419
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 7748)
  AUTHORS   Kaplan,E., Sela,N., Doron-Faigenboim,A., Navon-Venezia,S.,
            Jurkevitch,E. and Cytryn,E.
  TITLE     Genomic and Functional Characterization of qnr-Encoding Plasmids
            from Municipal Wastewater Biosolid Klebsiella pneumoniae Isolates
  JOURNAL   Front Microbiol 6, 1354 (2015)
   PUBMED   26696974
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7748)
  AUTHORS   Kaplan,E., Sela,N., Doron-Faigenboim,A., Navon-Venezia,S.,
            Jurkevitch,E. and Cytryn,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-2015) Plant Pathology and Weed research, ARO,
            volcani center, POB 6, Beit-Dagan, NA 50250, Israel
COMMENT     ##Assembly-Data-START##
            Assembly Method              :: a5_assembly v. 20150522
            Sequencing Technology        :: Illumina
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Name              :: GCF_009967065.1-RS_2024_05_16
            Annotation Date              :: 05/16/2024 01:46:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.7
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 10
            CDSs (total)                 :: 10
            Genes (coding)               :: 10
            CDSs (with protein)          :: 10
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KT896500.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7748
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="I70"
                     /isolation_source="Shafdan Dan Region Wastewater Treatment
                     and Reclamation Project site"
                     /db_xref="taxon:573"
                     /plasmid="pKPSH70"
                     /collected_by="Eddie cytryn Lab"
     gene            complement(join(7703..7748,1..236))
                     /locus_tag="HTH19_RS00005"
     CDS             complement(join(7703..7748,1..236))
                     /locus_tag="HTH19_RS00005"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172688007.1"
                     /translation="MQFKRQGRRVQVLAYRGYDKEKRRAIVKMMGSIDVYSYEPSGGLI
                     ENLTDEEKTELQSYIETERQAAEKRSRVYYAKSAWGLLTYILTSRQAA"
                     /name="hypothetical protein"
     gene            694..1125
                     /locus_tag="HTH19_RS00010"
     CDS             694..1125
                     /locus_tag="HTH19_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004171598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_012537712.1"
                     /translation="MNTDESKRRRRGPAPLDATDKRGHTVSVRLNDAELARLDSQRDAV
                     QMQRGEYLRAAALHRLPPTIPAANREQWAELARTAANLNQIARHLNEGQRGDGERIGKA
                     LGLQLSAELANCLRLLVLVRGDLIGVKHDSEDVEDESEG"
                     /name="plasmid mobilization relaxosome protein MobC"
     gene            complement(1316..1672)
                     /locus_tag="HTH19_RS00045"
     CDS             complement(1316..1672)
                     /locus_tag="HTH19_RS00045"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_043849886.1"
                     /translation="MQTLARRFVARSHGHVDLLVGQLPALGPRIAQPRRQGQAVGMLKL
                     LGRLDGAAGFPLAQPNFPVQPYPAGHDVDVILVRVLVAHCHPRRIGLVKAHALHEVSRH
                     GFPLLGAQALTGRQ"
                     /name="hypothetical protein"
     gene            1881..2564
                     /locus_tag="HTH19_RS00050"
     CDS             1881..2564
                     /locus_tag="HTH19_RS00050"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_043849885.1"
                     /translation="MTKLETVRALNDSGPQLQIVESVRTLQQSLSLMHEDLKRLPVAVS
                     TETAQTLEPLARLQQDVTQVLEAYDKVTAIQRKTLDELTQQMSASAAKAFEQKAGELDK
                     TISDLSNSLSGLETSISSMKQTAEQVADLPGNLVSAQKDMTQAANKLTEAANETRPRLW
                     RQALGLILAGAVGAMLVATGQVALNRLVPPSDVQQTADWANAIWNKATPKERELLEQIV
                     NRPAN"
                     /name="hypothetical protein"
     gene            2600..3550
                     /locus_tag="HTH19_RS00055"
     CDS             2600..3550
                     /locus_tag="HTH19_RS00055"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_043849884.1"
                     /translation="MKREGRHLSVKAGGDEAYRVTRQQDGRWLWCDRYGNDGGDNIDLV
                     REIEPGTGYAEAVYRLSGAPTVRQQPRPSEPKRQPPQLPAQGLAAREHGRDYLKGRGIS
                     PDTIEHAEKAGMVRYADGGVLFVGYDRTGTAQNATRRAIAPADPVQKRDLRGSDKIYPP
                     ILPGDPAKVWIVEGGPDALALHDIAKRSGQQPPTVIVSGGANVRSFLERDDVQAILKRA
                     ERVTVAGENEKNPEAQAKADAGHQKQAQRVAEITGREVRQWTPKPEHGKDLADMNARQV
                     AEIERKRQAEIEAERARNRELSRKSRGYDGPSFGR"
                     /name="hypothetical protein"
     gene            3621..4484
                     /locus_tag="HTH19_RS00020"
     CDS             3621..4484
                     /locus_tag="HTH19_RS00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014003865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="WP_012537710.1"
                     /translation="MAINIMEAFQQEPPQLDFIWPGFLAGTVGALVAPGATGKSFWALE
                     AAMSIACSVAGGDVVNLKPQHTGRVVYLAGEDPEPALIRRVHAIGQHLNQSAREAIAEN
                     LTLEPIMGKRLNVMDEEHLRRVIEYSAGARLIVLDTLSRIHSLDENSNGDMARLVATLE
                     HVAASTGASVLYLHHVSKGSAREGQTDQQQAARGASALIDNARWCGFVAKMTEDEAKRL
                     SDRAYDRQPIGNDRRGFFVRFGVSKQNYDATPLDQWYERRDGGVLVPVELLEVPNGKKG
                     GSREQA"
                     /name="helicase RepA family protein"
     gene            4471..5352
                     /gene="repC"
                     /locus_tag="HTH19_RS00025"
     CDS             4471..5352
                     /gene="repC"
                     /locus_tag="HTH19_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014003864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein C, IncQ-type"
                     /protein_id="WP_012954629.1"
                     /translation="MSKHDLTHARHDPAHCLAPGLFRSLKRGERKRGKLDVVHDYGDGK
                     RIEFSGPEPLGADDLRILQGLVAMAGPGGLVLSPEPQTEAGQQLRLFLEPKWEAFQQDA
                     MVVKGSYRALAREIGYANPDDTKPVRECIERLWKVSIIAQNGRKRQGFRLLSEYASDEQ
                     DGKLYVALNPLIARAVMGGAQHVRIDMDEVRALQTDPARLMHQRLCGWIDPGKSGRVEL
                     DTLCGYVWPGQATNPNTLKTRRQAARRALPELAALGWAVSEYAKNKFEIGRPKATHLLG
                     PAPKTQEISHEK"
                     /name="repC"
     gene            5342..5593
                     /locus_tag="HTH19_RS00030"
     CDS             5342..5593
                     /locus_tag="HTH19_RS00030"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_064163397.1"
                     /translation="MRNDWETPPTVEVRIPVKLNSDSGICEHHFRKVCGQGFFEQKLGF
                     EGRHLFDSLNKPAAKRSAAVVDPRRWNRTVHLTSEYVL"
                     /name="hypothetical protein"
     gene            complement(5896..6552)
                     /locus_tag="HTH19_RS00035"
     CDS             complement(5896..6552)
                     /locus_tag="HTH19_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrS2"
                     /protein_id="WP_012537714.1"
                     /translation="METYRHTYRHHSFSHQDLSDITFTACTFIRCDFRRANLRDATFIN
                     CKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIELRECDLKGANFSRANF
                     ANQVSNRMYFCSAFITGCNLSYANMERVCLEKCELFENRWIGTHLAGASLKESDLSRGV
                     FSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIASWQQEQLLEALGIVVFPD"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrS2"
     gene            complement(7368..7748)
                     /locus_tag="HTH19_RS00040"
     CDS             complement(7368..7748)
                     /locus_tag="HTH19_RS00040"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172688006.1"
                     /translation="MGSIDVYSYEPSGGLIENLTDEEKTELQSYIETERQAAEKRSRVY
                     YAKSAASRIVEVADTIKAGDFEPSEAWAADTWAAIEALTKAMRKAGYPKLRKAPQKAAD
                     APMPGQAGLPFGDAPETPESAS"
                     /name="hypothetical protein"
     ARG             complement(5900..6552)
                     /name="qnrS2"
                     /gene="qnrS2"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrS2"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          3622..4484
                     /name="IncQ2"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.495"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1110..3547
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.401"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gcagacttag cgtaatacac tcggcttctc ttttctgctg cctgtcgttc tgtttcgatg
       61 tatgactgta gttctgtttt ttcttcgtct gtcagattct caattaggcc gcctgacggc
      121 tcgtaagaat atacgtcaat agaccccatc atcttgacga tggcgcggcg tttttccttg
      181 tcataccccc ggtaggcgag cacctgaacc cggcgacctt ggcgcttaaa ctgcatggcg
      241 gtttctccgt ttgactgtgt gattatatta tagttcgaca gtcgcacgct gtcgagtgtt
      301 tattgtcggc ctatttttca atccgaccgt cgcactcaaa taggtttgca ctgtcggatt
      361 gagtaacgct cgacagtctg ccgttcttgc gataccatag ttgcattgta tcagttcgcc
      421 ccggcgcctt gcccaccccc tctccccgct ggcccattac cgcccttggg cggtcgggcc
      481 gagagcgcag cgagcgggcc gggtgggtgg ctgttcggtg cttgcatgga gatgtgctat
      541 tatggtattt gcgcggtggt ttggcatgga gcaaggtgta acctacgctt cgcttggttc
      601 tcaccctccg gccttcggcc tacgcccccg ctcccttcgg tcggggggtt gctgcgcgtt
      661 tcgcttcgct tcacttactg gagggcttcg cccatgaaca ctgacgaatc caagcgccgc
      721 cgccgtgggc ctgcgccgct cgacgccacg gacaagcgcg ggcataccgt ttcggtgcgc
      781 ctcaacgatg ccgagcttgc gcggctggat tcgcagcgtg acgcggtgca gatgcagcgg
      841 ggcgagtacc tacgcgccgc cgctctgcat cgcctgccgc ccaccatccc ggcagcgaac
      901 cgggaacagt gggcagagtt ggcccgcaca gcggccaacc tgaaccagat cgcccggcac
      961 ctgaacgaag ggcagcgggg cgacggggag cgcatcggca aggcgctggg cttgcagttg
     1021 agcgccgagc ttgccaactg cctgcgattg ctggttctgg tgcgcggcga cttgataggc
     1081 gtcaagcacg actcggagga cgtggaagat gaaagcgaag gttagccgtg gtggcggttt
     1141 tcgcggtgcg ctgaactacg tttttgacgt tggcaaggaa gccacgcaca cgaaaaacgc
     1201 ggaacgtgtc ggcggcaaca tggccgggaa tgacccccgc gaactgtcgc gggagttctc
     1261 agccgtgcgc cagttgcgcc cggacatcgg caagcccgtc tggcattgct cgctgtcact
     1321 gcctcccggt gagcgcctga gcgccgagaa gtgggaagcc gtgacgactg acttcatgca
     1381 gcgcatgggc tttgaccaga ccaatacgcc gtgggtggca gtgcgccacc aggacacgga
     1441 caaggatcac atccacatcg tggccagccg ggtagggctg gacgggaaag tttggctggg
     1501 ccagtgggaa gcccgcagcg ccatcgaggc gacccaagag cttgagcata cccacggcct
     1561 gaccctgacg ccggggctgg gcgatgcgcg ggccgagcgc cggaagctga ccgacaagga
     1621 gatcaacatg gccgtgagaa cgggcgacga accgccgcgc cagcgtctgc aacggctgct
     1681 ggatgaggca gtgaaggaca agccgaccgc gccagaactg gccgaccggc tacatgccgc
     1741 aggcgtaggc gtccgggcaa acctcgccag caccgggcgc atgaacggct tttccttcga
     1801 ggtggccgga gtgccgttca agggcagcga cttgggcaag ggctacacat gggcgggact
     1861 acagaaatca ggggtgactt atgacgaagc tagagaccgt gcgggccttg aacgattcag
     1921 gcccacagtt gcagatcgtg gagagcgtca ggacgttgca gcagtccctg agcctgatgc
     1981 acgaggactt gaagcgccta ccggtcgcag tctcgaccga gacggcgcag accttggaac
     2041 cgctggcccg actccaacag gacgtgacgc aggttctgga agcctacgac aaggtgacgg
     2101 ccattcagcg caagacgctg gacgagctga cgcagcagat gagcgcgagc gcggcgaagg
     2161 cgttcgagca gaaggccggg gagctggaca agaccatctc cgacctgtcc aacagcctgt
     2221 cagggctgga aacgagcatc agcagcatga agcagaccgc ggagcaggtg gcggacttgc
     2281 cgggcaatct ggtgagcgca cagaaggaca tgacgcaagc cgccaacaaa ctgaccgagg
     2341 cagcgaacga gacgcgcccg cgcctttggc ggcaggcgct ggggctgatt ctggccgggg
     2401 ccgtgggcgc gatgctggta gcgactgggc aagtcgcttt aaacaggcta gtgccgccaa
     2461 gcgacgtgca gcagacggcg gattgggcca acgcgatttg gaacaaggcc acgcccaagg
     2521 agcgcgagtt gctggaacag atcgtcaatc ggcccgcgaa ctagatccga ccgcctacct
     2581 tgaggcgagc ggctacaccg tgaagcgcga agggcgacac ctgtccgtca aggctggcgg
     2641 tgatgaggcg taccgcgtga cccggcagca ggacgggcgc tggctctggt gcgaccgcta
     2701 cggcaacgac ggcggggaca atatcgacct tgtgcgcgag atcgaacctg gcaccggcta
     2761 cgccgaggcc gtctatcggc tttcaggtgc gccgacagtc cggcagcaac cgcgcccgag
     2821 cgagccgaaa cgccaaccgc cgcagctacc ggcgcaaggg ctggcagccc gcgagcatgg
     2881 ccgcgactac ctcaagggcc ggggcatcag cccggacacc atcgagcacg ccgagaaggc
     2941 gggcatggtg cgctatgcag acggtggcgt gctgttcgtc ggctacgacc gtacaggcac
     3001 cgcgcagaac gccacacgcc gcgccattgc ccccgctgat ccggtgcaga agcgcgactt
     3061 acgcggcagc gacaagatct atccgccgat cctgccgggc gacccggcaa aggtctggat
     3121 cgtggaaggt ggcccggatg cgctagccct gcacgacatc gccaagcgca gcggccagca
     3181 gccgcccacc gtcatcgtgt caggcggcgc gaacgtgcgc agcttcttgg agcgtgacga
     3241 cgtgcaagcg atcctgaagc gggccgagcg cgtcactgtg gccggggaaa acgaaaagaa
     3301 ccccgaggcg caggccaagg ccgacgccgg gcaccagaaa caggcgcagc gggtggccga
     3361 aatcaccggg cgcgaggtgc gccaatggac gccgaagccc gagcatggca aagacttggc
     3421 cgacatgaac gcccggcagg tggcagagat cgagcgcaag cgacaggccg agatcgaggc
     3481 tgagagagcg cgaaatcgag agctttcacg caagagccgg gggtatgatg gccccagctt
     3541 cggcagataa gagcgcctgt cagtcggtgt gatgaaccga ccgacaggct aaccatcatc
     3601 aacctgagta ggaggccgat atggctatca acattatgga ggcgttccag caggaaccgc
     3661 cacaactgga cttcatctgg cccggctttc tggctggcac cgtgggcgca ctggtggccc
     3721 ccggcgcgac cggcaagagc ttctgggcgc tggaagcggc tatgtccatc gcttgcagcg
     3781 tggcaggcgg tgacgtggtg aacctcaagc cgcagcacac cgggcgcgtg gtctatctgg
     3841 ccggtgaaga tcccgaaccc gccctgatcc ggcgcgttca cgccatcggc cagcacctca
     3901 accagtcagc ccgcgaagcc atcgccgaga acctgaccct tgagccgatc atgggcaagc
     3961 gcctgaacgt catggacgag gagcacttgc gccgcgtcat cgagtacagc gccggggcgc
     4021 ggctgatcgt gctggacacc ctgagccgga ttcacagcct cgacgagaac agcaacggcg
     4081 acatggcgcg gcttgtcgcc acgctggaac acgtcgcggc cagcactggc gcgtctgtcc
     4141 tgtacctgca ccacgtcagc aagggcagcg cccgcgaggg gcaaaccgac cagcagcagg
     4201 cagcgcgggg cgcatcggca ctgatcgaca acgcccgctg gtgcggcttc gtcgccaaga
     4261 tgaccgagga cgaggccaag cgcctgagcg accgcgccta tgaccgtcag cccatcggca
     4321 acgaccggcg cggcttcttc gtgcgcttcg gcgtgagcaa acagaactac gacgccaccc
     4381 cgcttgacca gtggtatgag cgccgagacg gcggcgtgct ggttccggtg gaactgctgg
     4441 aagtgccgaa cggcaagaag gggggcagcc gtgagcaagc atgacctgac ccacgcccgg
     4501 cacgacccgg cgcattgtct ggcccccggc ctattccgca gcctcaagcg tggcgagcgc
     4561 aagcgcggca agctggacgt ggtgcatgac tatggcgacg gtaagcgcat cgagttcagc
     4621 ggcccggagc cgctgggcgc tgatgacttg cgcatcctgc aaggacttgt ggcaatggct
     4681 gggccgggtg gccttgtgct gtcacctgag ccgcagaccg aggccgggca gcaactccgg
     4741 ctgttccttg agccgaaatg ggaagccttc cagcaggatg cgatggtggt caagggcagc
     4801 tatcgagcac ttgcccgcga aattggctac gccaaccccg acgacactaa gccggttcgg
     4861 gagtgcatcg agcggctttg gaaggtgtcc atcatcgccc agaacggcag gaagcggcag
     4921 ggcttccgcc tgctgtccga gtacgccagc gacgagcagg acggaaagct gtatgtagcc
     4981 ttgaatcccc tgattgctcg cgccgtcatg ggtggcgcgc agcatgtccg catcgacatg
     5041 gacgaggtgc gggcgctaca gaccgacccg gcgcggctga tgcaccagcg cctatgcggc
     5101 tggatcgacc ccggcaagtc cgggcgggtg gaactggaca cgctttgcgg ctacgtctgg
     5161 ccggggcagg caaccaaccc caatacgctc aagacgcgac gccaagcggc tcgcagggcg
     5221 cttcctgagc ttgccgcatt gggctgggca gtcagcgaat acgcaaaaaa caagtttgaa
     5281 atcggcaggc cgaaagcaac gcatctgctc ggcccagcac ccaaaacaca ggaaattagc
     5341 catgagaaat gattgggaaa cgccgccgac agtcgaagtg cgtattccgg tgaagttgaa
     5401 cagtgattcc ggaatctgtg aacaccattt ccggaaagta tgcggacagg gattcttcga
     5461 gcagaagctg ggctttgagg ggaggcatct tttcgactca ctgaacaagc cagcagccaa
     5521 gcgcagcgcg gcagttgtgg atccaagacg ttggaacagg acggttcatc tgacatcaga
     5581 gtacgtgctc tgaggtgttg taggagagga ataaagtttc atactaagca gtcaagtaac
     5641 cctgtttgta ccgttctaaa tgatactcac ccagaaataa agattcatac taattcctac
     5701 tacaaaatct gagtcacgct acaactgagt aataaagtat catactggtt gtcttgagca
     5761 tccacagatt gattggcccc attcaaacac gtttctggac aagaatgagc tagaagtatt
     5821 gatctagctc tggtgatttg aattagaaaa tgtattaatg ttgtgtatag tttatcagca
     5881 ggtattcgta agcatctagt caggaaaaac aacaataccc aacgcttcga gaagctgttc
     5941 ttgttgccag ctggcaattt tgatacctga tgtatcgact tttcgaggat ctaaaccgtc
     6001 gagttcggcg tgacataaat tagcaccctg taggctaaac tgtccccaga catcttcaga
     6061 aaaaacacct cgacttaagt ctgactcttt cagtgatgcg cccgcgaggt gagtccctat
     6121 ccagcgattt tcaaacagct cacatttttc taaacagacc cgctccatat tggcataaga
     6181 caggttacat ccagtaataa aggctgagca aaagtacata cgattactca cttgattggc
     6241 aaagtttgct cgggaaaagt tggccccttt taaatcacac tcacgtaact caataccgta
     6301 gcaattggcg ttactaaagt ttgccatcgc aagctggcat tgttggaaac ttgcatcgcg
     6361 aaggtctgcg acatcaaaat ggcaaccttc gatatcaccc tgttcaatga acttgcagtt
     6421 aataaatgtc gcatcacgca agttagcacg tcgaaaatcg catcggataa aggtgcaagc
     6481 agtgaaagta atatcactta gatcttgatg tgaaaaactg tggtgtcgat atgtgtgacg
     6541 gtaggtttcc atgttgactc ctatgatgaa ctggacgcaa cactaccatc aaagccacat
     6601 cacatcacca aaataaaaac actaaaaatc aagatcttaa aaaccctcat tttgcctatt
     6661 ttaagggggt aaaatagcgc cctgagcctc tatgttaacg ttcaaagtac gcggcaccat
     6721 tgaaaaaagt tatccgctta aaaagccaca gagaaaagga acccaataga ttactgatgt
     6781 ccgccattag gtaaagtaac cttaaacgga agcctgcaat ttgaagtaga tacaaggtct
     6841 aagaaggaat ggttggctgt tttattttat tgtactcggc attaagccca atttctttag
     6901 cgttacgata agctagcatg gctacaccga ccccgctagg ctgattggga agcgttgcct
     6961 gatctactca ggagggcgct tcgataacgt agccattgag ccggaaaccg gcgagcactg
     7021 gggcagcgtg atctggtgcg agtatgtgtg accccctgtt taactccacc caacccccac
     7081 ggtaactcca cccaaccccc acggtaactc cacccgcccc gatctggaaa acccagacgg
     7141 ggcgcggatt tgctggcgat tcgcaaaatc catccaagat tctctaagaa tctccactag
     7201 gcgcagcaca gcccgcgccc cttcggcgcg gtctggcatt gcctcaaatg cccggccaag
     7261 accatgcgca aggcgaacac ctctcccccc gccttcggcg accccctccg ggggtaaagg
     7321 gccagcgggg agaggggggg gggtgccggt ttcccggcct aaacccctca ggaggcgctt
     7381 tctggcgttt ctggcgcatc cccaaagggc aaccccgcct gacccggcat cggcgcgtct
     7441 gcggctttct ggggcgcttt gcggagcttc gggtagcccg ccttgcgcat ggccttggtc
     7501 agcgcctcga ttgccgccca ggtatccgcc gcccatgcct cggacggctc aaagtccccg
     7561 gccttgatcg tgtcggcaac ctcaacaata cgactggcgg cagacttagc gtaatacact
     7621 cggcttctct tttctgctgc ctgtcgttct gtttcgatgt atgactgtag ttctgttttt
     7681 tcttcgtctg tcagattctc aattaggccg cctgacggct cgtaagaata tacgtcaata
     7741 gaccccat
//
