LOCUS       NZ_KJ187750            10047 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium strain
            AC06.010 plasmid pSQR1, complete sequence.
ACCESSION   NZ_KJ187750
VERSION     NZ_KJ187750.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14226745
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium (Salmonella
            typhimurium)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10047)
  AUTHORS   Chen,Y.-T., Liao,T.-L., Lin,A.-C. and Lauderdale,T.-L.
  TITLE     Plasmid-mediated quinolone resistance qnrS from Salmonella enterica
            serovar Typhimurium in Taiwan
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10047)
  AUTHORS   Chen,Y.-T., Liao,T.-L., Lin,A.-C. and Lauderdale,T.-L.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2014) National Health Research Institutes,
            Institute of Molecular and Genomic Medicine, 35, Keyan Road, Zhunan
            Township, Miaoli County, Taiwan 350, Taiwan
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: Consed v. 23
            Sequencing Technology             :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:08:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 14
            CDSs (total)                      :: 14
            Genes (coding)                    :: 10
            CDSs (with protein)               :: 10
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 4
            CDSs (without protein)            :: 4
            Pseudo Genes (ambiguous residues) :: 0 of 4
            Pseudo Genes (frameshifted)       :: 1 of 4
            Pseudo Genes (incomplete)         :: 4 of 4
            Pseudo Genes (internal stop)      :: 1 of 4
            Pseudo Genes (multiple problems)  :: 1 of 4
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KJ187750.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..10047
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium"
                     /mol_type="genomic DNA"
                     /strain="AC06.010"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /db_xref="taxon:90371"
                     /plasmid="pSQR1"
                     /geo_loc_name="Taiwan"
     gene            237..395
                     /locus_tag="HTC39_RS00005"
     CDS             237..395
                     /locus_tag="HTC39_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001658417.1"
                     /translation="MHEPPVQSDCCASSGNFQLDSNPERHDKAPLAAAIGNWELVDLDI
                     ESLEVVA"
                     /name="hypothetical protein"
     gene            complement(638..943)
                     /locus_tag="HTC39_RS00010"
     CDS             complement(638..943)
                     /locus_tag="HTC39_RS00010"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_223229636.1"
                     /translation="MPKPDNSCCRSEDIVCRFGGEEFVVFLPNTSVVTAECVAERIRSV
                     IESTVFPNNLRVTVSAGVATQEDPLGGIDFLLKNADDALYQAKGEGRNKVIVYSAI"
                     /name="GGDEF domain-containing protein"
     gene            complement(<929..1959)
                     /locus_tag="HTC39_RS00015"
                     /pseudo=""
     CDS             complement(<929..1959)
                     /locus_tag="HTC39_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612174.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            2354..3010
                     /locus_tag="HTC39_RS00020"
     CDS             2354..3010
                     /locus_tag="HTC39_RS00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrS1"
                     /protein_id="WP_001516695.1"
                     /translation="METYNHTYRHHNFSHKDLSDLTFTACTFIRSDFRRANLRDTTFVN
                     CKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIEFRACDLKGANFSRTNF
                     AHQVSNRMYFCSAFISGCNLSYANMERVCLEKCELFENRWIGTNLAGASLKESDLSRGV
                     FSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIAAWQQELILEALGIVVYPD"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrS1"
     gene            complement(3329..3943)
                     /locus_tag="HTC39_RS00025"
     CDS             complement(3329..3943)
                     /locus_tag="HTC39_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017412822.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_014839983.1"
                     /translation="MFIGYIRMSKADGSQTNDLQRDALIAAGVDAAHFYEDRASGKREE
                     RPGLTACLKALRPGDTLVVWKLDRLGRDLRHLINTVHDLTARGTGLKVLTGHGATIDTT
                     TAAGKLVFGIFAALAEFERELIAERTTAGLASARARGRNGGRPYKMTPVKLRLAMASMG
                     QSETKVSTLCQELGITRQTLYRHISPVGQLRADGIKLFNRG"
                     /name="recombinase family protein"
     gene            4105..>4287
                     /locus_tag="HTC39_RS00030"
                     /pseudo=""
     CDS             4105..>4287
                     /locus_tag="HTC39_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060658.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            4423..4968
                     /locus_tag="HTC39_RS00035"
     CDS             4423..4968
                     /locus_tag="HTC39_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid pRiA4b ORF-3 family protein"
                     /protein_id="WP_001493763.1"
                     /translation="MVWRRLRIAADTSLAALHFIFQIVQGWGDDHLHQFHIYGKDYGIS
                     YEGGIGFVDNPFRVVIDDFAFDAGDRFTYEYNFFEHWLHDIRVEAIYENSTLKAPFCIS
                     GHGMPGATAADEFDKTLAFLEAIVNADDETTVGEIRPFADDLDAVRFNRHKINRQLSRL
                     DLASPVLEPEVIWLGRRR"
                     /name="plasmid pRiA4b ORF-3 family protein"
     gene            5105..5677
                     /locus_tag="HTC39_RS00040"
     CDS             5105..5677
                     /locus_tag="HTC39_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493762.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001493762.1"
                     /translation="MQYAYIRVSSADQNTARQEEALSKAGFQPDKICVEHASAKDTNRP
                     GLQELLGQLRPGDTLLVHSIDRLCRNMSDMCAVTTRLRDQGVTLIFLKEQLTFSAGTNN
                     PMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEKTGRPGADIKKIQEIDALRSRG
                     VRLRIACDHAGLGVSTYYKLRHQMNNQ"
                     /name="recombinase family protein"
     gene            5714..>6319
                     /locus_tag="HTC39_RS00045"
                     /pseudo=""
     CDS             5714..>6319
                     /locus_tag="HTC39_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493761.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ISKra4-like element ISKpn19 family transposase"
                     /name="ISKra4-like element ISKpn19 family transposase"
     gene            complement(6247..7623)
                     /locus_tag="HTC39_RS00050"
     CDS             complement(6247..7623)
                     /locus_tag="HTC39_RS00050"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017900944.1"
                     /GO_function="GO:0009975 - cyclase activity [Evidence IEA]"
                     /GO_process="GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="WP_080196049.1"
                     /translation="MVNVEFFNYIECIFMRIKKPHLRPIVITLSVGGILLTSIFLIVVI
                     MVFKRENIEKDLLDANSSYAMKMSDVMSNYIEIAQRELAYGAKKIESTNDIDSLKNEAD
                     RLRLQSGMFNSVLVVSDGAVVLATSPESLGLVGVHLNSSASKLAIEAKKPFISAPYKSA
                     SGNLIIFLSHPIYDKNSNYIGYVGGSIYLKEQSLFSDVLSRHFFKSDTEISIVSDDGNV
                     IFNNDNSAVGRPMVMDDNLKSKLTSSERGEGIFFSSGNKYLLGYAHMKNTAWSVLVYSH
                     ADSVTTILITYAKSVLVLLIVIVITFSLFSYFIASRISIPLEKLAISTNAKDIGGSLVD
                     IKGINAWYVEADRLKKALFTHIKIMIERVDSLNEVALKDPLTGVNNRLGFSNKIQNHKQ
                     GSGASVIAIDVDFFKKINDNFGHGVGDEVLVTLAQVINCGFPGLGRFPQSRGQPERKPE
                     "
                     /name="diguanylate cyclase"
     gene            complement(7929..8144)
                     /locus_tag="HTC39_RS00055"
     CDS             complement(7929..8144)
                     /locus_tag="HTC39_RS00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_000137421.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWENAFAEWRTMSGLMQRENA
                     ALSERVTGLSRQVQSLSEQLRRLSQG"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(8148..8633)
                     /locus_tag="HTC39_RS00060"
     CDS             complement(8148..8633)
                     /locus_tag="HTC39_RS00060"
                     /inference="COORDINATES: protein motif:HMM:NF016710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_012482081.1"
                     /translation="MSSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEQSVRAELNESE
                     KRISAAILDHDRKLSSAMSQRTKGMVRMVSQTWLTIVLVSVLLIASSAGILWWQSQQIL
                     DNYTTIREQKSTQAMLSERNSGVQLSTCGEQRRSCVRVNPEAGRFGEDSSWMILAGK"
                     /name="MbeB family mobilization protein"
     gene            complement(<8668..9372)
                     /locus_tag="HTC39_RS00080"
                     /pseudo=""
     CDS             complement(<8668..9372)
                     /locus_tag="HTC39_RS00080"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(9311..9634)
                     /locus_tag="HTC39_RS00070"
     CDS             complement(9311..9634)
                     /locus_tag="HTC39_RS00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_015059464.1"
                     /translation="MLTIWVTEDEHRRLLDRCDGKQLAAWMRQTCLDEKPARAAKLPSI
                     SPALLRQLAGMGNNLNQIARQVNAGGGTGHDRVQIVAALMAIDAGLERLRHAVLEKGAD
                     DDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     ARG             2355..3007
                     /name="qnrS1"
                     /gene="qnrS1"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrS1"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          2..350
                     /name="rep_cluster_2373"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.571"
                     /coverage="81.0"
                     /evalue="3.79e-163"
     Typing          complement(7826..9321)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="91.583"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tttccatagg ctccgccccc ctgacaagca tcacagaatc tgacgctcaa atcagtggtg
       61 gcgaaacccg acaggactat aaagatccca ggcgtttccc cctggtagct ccctcgtgcg
      121 ctctcctgtt cctgcctttc ggtttaccgg tgtcattccg ctgttatggc cgcgtttgtc
      181 tcattccacg cctgacactc agttccgggt aggcagttcg ctccaagctg gactgtatgc
      241 acgaaccccc cgttcagtcc gactgctgcg cctcctccgg taactttcaa cttgattcca
      301 acccggaaag gcacgacaaa gcgccactgg cagcagccat tggtaactgg gaattagtgg
      361 atttagatat cgagagtctt gaagtggtgg cctgactacg gctacactga aaggacagta
      421 tttggtatct gcgctccact aaagccagtt accttcggaa gaaagtgttg gtagctctta
      481 attccggcaa acgaaccacc gttggtagcg gtggtttttt tgtttacagg gcatgagctt
      541 acgacgacat cgaagggata acaagaggat ccgcttcttg aacccttttc cccacaaaaa
      601 aacgccacac tagcgcgtaa agcgtcatca aaaaaactca aatagcgcta tatacaatca
      661 ctttattacg cccctctccc ttggcttgat aaagagcatc atcagcattt ttcagcaaaa
      721 aatcgatccc accaagagga tcctcttgtg ttgccacacc agcagagacg gtgacccgca
      781 agttattagg gaaaacagta ctttcaataa cactcctaat acgctccgca acacactccg
      841 ctgttaccac agatgtattc ggcagaaaaa caacaaactc ttctccacca aaccgacaaa
      901 caatatcttc actacggcag caagaattat ccggtttcgg catgatgctg atgtagtccc
      961 gttttatcgt catcacgaag ctttctgcta tgccattgct ttccgggctt cgcactgctg
     1021 tcgtacaagg ctccagtccc agcaaccggg cgaacgccgg cactgttggc aactgccttc
     1081 cgaagcgttt ttccaccgca cccagcatga catcctgcac cgtttctttg tcatagcctc
     1141 cggtgctcgc tgcccaatca atgatctccc tgtcgcagca gtcctgcgcg aaggtcaccc
     1201 gcagcttttc gccattatca cagcggaact caaagccatc tgagcaccag cgccggttac
     1261 tttccgctac tgctacgcgc cccttatggg cccgcttacg gcaaggatca gcgggtttac
     1321 gttcaagaag cagattatgc gttctcataa tgcgatacac ccgctttgca ttaaccacag
     1381 gcaggccgtc ccgctccgac tcccgtcgca gcagcgccca cacacggcga taaccatacg
     1441 tcggcaggtc agccaccgcc atgtttatcc gggacaatac ggtggtatcg tcagaacggg
     1501 gctgccgtct gcgatcctgt cagtcagatg gccggtgaac ccgaatgctc aactgcgcac
     1561 gcgacacgcc aagacttctg caaacgtcgc ttattcgtcg ttcccaggca acgagggcgc
     1621 atgcgcaatc catttttttg cccggccgaa ctccacggcc tctttgagta tctcggcttc
     1681 catcgtcttt ttgcccagaa ggcgctggag ttcgcgaatt tgcttattgg cggcagcgag
     1741 ttcggaggcc ggcaccactt cctcgcccga tgcaacagcc gtcagtgaac cgtcttaata
     1801 ttgcttgcgc catttgaata tctggtttgc attgatgcca tgcaggcgcg cgacatgaga
     1861 cacggtcata ccgggctcca tagtctgctg aataatggca attttttcct gcggtgtacg
     1921 acgccgacgc cgctcaggtc ctgataacac ttcaaccatc ttatcgttct gactggtatt
     1981 aaacatagtt ccaagactac ctcttatttt aagagagtcg aagtgtctgg tgatctatgg
     2041 ggccagtcta gccctcttcc aagtgtaggg agatatagtc aaagtttgct tctccgccga
     2101 tgagtccgcc ctgcgtcgga tagtccgatt ttttaccggc gaagcacggc tctcctaacc
     2161 ctatctaaag cgaataactt ttttcaacag ggccgcgtgc caatgcaaga gcgataggcg
     2221 ctctacgcgc caatttgacc acttaaaaca ggtaaattga ggggttgtaa tgtgttgatg
     2281 taacaggctt ttattttaat gtcttggcat atgtataatg gtagtctagc cctcctttca
     2341 acaaggagta ctcatggaaa cctacaatca tacatatcgg caccacaact tttcacataa
     2401 agacttaagt gatctcacct tcaccgcttg cacattcatt cgcagcgact ttcgacgtgc
     2461 taacttgcgt gatacgacat tcgtcaactg caagttcatt gaacagggtg atatcgaagg
     2521 ctgccacttt gatgtcgcag atcttcgtga tgcaagtttc caacaatgcc aacttgcgat
     2581 ggcaaacttc agtaatgcca attgctacgg tatagagttc cgtgcgtgtg atttaaaagg
     2641 tgccaacttt tcccgaacaa actttgccca tcaagtgagt aatcgtatgt acttttgctc
     2701 agcatttatt tctggatgta atctttccta tgccaatatg gagagggttt gtttagaaaa
     2761 atgtgagttg tttgaaaatc gctggatagg aacgaaccta gcgggtgcat cactgaaaga
     2821 gtcagactta agtcgaggtg ttttttccga agatgtctgg gggcaattta gcctacaggg
     2881 tgccaattta tgccacgccg aactcgacgg tttagatccc cgcaaagtcg atacatcagg
     2941 tatcaaaatt gcagcctggc agcaagaact gattctcgaa gcactgggta ttgttgttta
     3001 tcctgactaa ttgctttgat gtgtgatttt aaacgctcaa atttataaaa cgaataatat
     3061 tgtcaacctt gcaataatag acatagggac aaccatgtat aaatttttac cctcaggcgt
     3121 cttcacaata gagccatata gcagtgggtc acttagtggg cttaattttt ccattaaaga
     3181 taatattaat attgctcagt ataaaacatc atatggtagc ccatcttggc aagtaaacat
     3241 aaggctgcca tttataaggc actgttgcaa aaatgtggag gtgatagggg tactacgccg
     3301 gaaccccaga tttttccgtc cgttcaaatt atccacggtt gaacagcttg atcccgtccg
     3361 cccgcagttg accaacaggg gaaatatgcc tgtacaaagt ttgccgggtt atcccaagtt
     3421 cctggcatag cgtactgacc tttgtttctg attgtcccat tgatgccatt gccagtcgca
     3481 gtttgactgg cgtcatttta taaggtcggc cgccgttccg cccacgggct cttgctgatg
     3541 ccagacctgc agtcgttctt tcagcaatca gttcgcgctc aaactccgcc agtgcggcaa
     3601 agataccgaa gacaagcttg ccagcggccg ttgttgtgtc gatagtcgcc ccgtgaccgg
     3661 tcagcacttt cagaccggtc cccctcgcgg tcaggtcgtg cactgtatta atgagatgac
     3721 gaagatcacg accgaggcgg tccagcttcc atacgaccag cgtgtctccg ggtcgtagtg
     3781 ctttcagaca ggctgtaagt ccaggacgct cttctcgttt gcccgatgcc cggtcctcat
     3841 aaaaatgtgc ggcatcaaca cctgcggcga tcagtgcatc acgttgtaaa tcattcgtct
     3901 gcgaaccatc agcttttgac atccgaatat atccgatgaa catatttcct ctgtcacata
     3961 tacgttcgat tatgtgacat tctgatttgg gtaccataat ctgtcaacgg tagtcacatt
     4021 acccgtaatt taaattatga cacgtaaagg ttctatgtta atgataatgt gacaagcgcg
     4081 tttaaatagg cataaggatc agagatgcct actaaaaata agctcctcag tattctttcg
     4141 gacgccgagc aggaagcgct ctatggtcta cctgatttcg atgatgcaca gcggctggag
     4201 tttctggcgc tgaatggata tgaactggcg ctggcctgca gtcgccgggg gcttcacgct
     4261 caaatttatt gcatcatcca gatcggagag catgaaaaac ctcggggcag ccatcgaatg
     4321 atgccatcta caggggttaa aataaccacc atcatttcat aacaatacct gctgactatg
     4381 aagatctacg tcatcaaaat agcagttcat ggagtcagtc cgatggtctg gcgtcggctg
     4441 agaattgctg ccgacacgtc actggccgcg cttcacttca ttttccagat agtgcagggc
     4501 tggggggacg accatctcca tcaatttcac atttatggca aagattacgg tatctcctac
     4561 gaaggaggca tcggttttgt cgataatccg ttccgggtcg tgattgatga ttttgctttt
     4621 gatgctggcg atcgctttac ctatgaatac aatttctttg agcactggct tcatgacatt
     4681 cgtgttgagg ccatttatga aaactctacg ctgaaagcgc cgttttgtat aagcggccat
     4741 ggtatgcccg gagccacagc tgcggatgag ttcgataaaa ccctggcgtt tcttgaagct
     4801 atcgttaatg cggatgatga aacaacggtc ggcgagatcc gcccttttgc tgacgacctg
     4861 gatgctgtca ggttcaaccg ccacaaaatc aaccggcaac tgagcaggct cgaccttgca
     4921 tctccggtac tggagcctga agttatctgg ctgggccgtc gtcgctgact gatgtctata
     4981 aaggtatacg ttttcagcat gcctctcaga tccccgaaaa aatgtctata aacctcccta
     5041 aatcagtgtt tatggattat tctttaaatc tctatgatgt ttaaagacct tccggaggtt
     5101 ttgcgtgcaa tatgcctaca tcagggtaag ctcggccgat cagaatacgg cccgtcagga
     5161 agaggcattg tcaaaggcgg gttttcagcc tgataaaatt tgtgttgagc atgccagcgc
     5221 gaaggacaca aaccgcccgg ggttacagga actcctgggg caattacgcc ctggtgatac
     5281 gcttctggtt cattccatcg atcgcctttg ccggaatatg tcggatatgt gcgctgtcac
     5341 cacccggctt cgtgaccagg gcgttaccct tatttttctg aaagagcagc tgacgttcag
     5401 cgccggcaca aacaatccga tgcaggaact gcagctgcac atgatgtcgg cattcagcca
     5461 gtttgaacga gccttactga aggaaaggca ggccgacggc atcgccgcga aaaaagcacg
     5521 gggtgaaaaa acagggcgcc ccggcgccga tatcaaaaag atccaggaaa ttgacgcact
     5581 cagaagcaga ggggtcaggc tcaggatcgc ctgcgaccat gcgggccttg gcgtttccac
     5641 atattataag cttcgtcacc agatgaacaa ccagtagccg ggagatagtc atccaccaca
     5701 gcaggaggca atgatgcaac tgacgctcca gatagtcatc accgatgaat caggctccag
     5761 tcgaacggag gaactgatga caatccagaa atcaggggag acccggaacg acatcggatt
     5821 atcggtgtca gaatccaagc tgttgctgaa tacggtccag cagtcggtgg tccagctgca
     5881 ggcagacgaa tatactcaac accatatccg gtgccctcac tgccttgctg cgcgcagaat
     5941 caaaggcaaa cagaaaatac ggtaccggac gctgtttggc gttattccgg tatccgggct
     6001 tcgggtgtac cggtgccgtt gtgaagagag tgatacaaag acagtcagtt tgctcagcga
     6061 ctgggccggc gattattctc acccggcact gaaatatatt gaaacccgct gggcctcgat
     6121 gatctcctat gaaatgacga ctcgtctgct gaaagatatt ctgccggtgg gccacagcct
     6181 gaatgcctca acggtgagga atcatttatg ccaggtggcg cagcgtcttg acgctgaggc
     6241 tgaagctcat tcaggttttc tttccggctg cccccgcgac tgggggaacc tgcccaggcc
     6301 aggaaaaccg caattaataa cctgagccaa agtaacaaga acctcatctc cgaccccatg
     6361 cccgaagtta tcatttattt ttttaaaaaa atcaacatca atagcaataa ctgaagcccc
     6421 tgaaccctgc ttgtgatttt gtattttatt tgaaaacccc agtctgttgt tcacgccggt
     6481 taggggatct ttaagcgcca cctcatttag agaatcaact ctttctatca ttatcttaat
     6541 atgcgtaaaa agtgcctttt ttagtcggtc ggcttcgaca taccaagcat tgataccttt
     6601 aatatcaact agcgaacccc ctatatcttt agcattggta gatatagcaa gcttttctaa
     6661 aggaattgaa atacgggaag caatgaaata tgaaaaaagt gaaaatgtaa taactattac
     6721 aattagcaga acaagtacac tcttagcata agtaataaga atagtagtca cgctgtcagc
     6781 gtgactataa accaacacac tccaagcagt atttttcata tgagcataac caagaagata
     6841 tttattcccc gaagaaaaaa agataccctc acctctctca gacgaagtta acttcgattt
     6901 caaattatca tccataacca ttggtcgacc aacagcactg ttatcgttat taaagatcac
     6961 atttccatca tcactaacaa tgctaatttc agtgtcgctt ttgaaaaaat gcctgctcaa
     7021 aacgtcgcta aataaactct gttcctttag atatatagac ccgccgacat accctatata
     7081 attactattc ttatcataaa taggatgtga caaaaaaata atcaaattcc cagaagctga
     7141 tttgtaaggt gccgatataa atggtttttt agcctcaatc gccaacttac tggcacttga
     7201 attcaagtga actccaacta aaccaagtga ttctggcgaa gtcgccagaa caacagcacc
     7261 atcactaaca acaagaactg aattaaacat accagactgc aatcttaacc tatccgcctc
     7321 atttttaagt gagtcaatat cattagttga ctctattttt tttgcgccat acgccaattc
     7381 acgttgagca atttcaatat aattactcat tacatctgac attttcatag cgtacgatga
     7441 attagcatca agcaagtctt tttctatatt ttcgcgttta aaaaccataa taacgacaat
     7501 cagaaaaata gaagtcaaca aaataccacc aacggacaag gttatgacta tcggacgaag
     7561 gtgaggcttt ttaattctca taaaaataca ctctatataa ttaaaaaatt ccacatttac
     7621 cataacatcc cttgcccgca ccgccccgga cgggttcggc gcgaatgcgg cgtcagcccg
     7681 gtaaaaccgg cagtaaactc cccgctaaac cgcgcttttt gagccagata aatttcccca
     7741 agatgcatag ccatgcagcc ggggggatgg caccgccttt cggcggggat ctgcgccgaa
     7801 agacccgttt tatccggttt gttacagcga cggaccgttg tacgtccgct ggcgctgcga
     7861 tcgttccagc tccagcgctt tccggtgctg cgccgcccgt tcctgctccc ggtgcgcctc
     7921 gataccattc agccttgcga caaccggcgc agctgctcgc tcaaactctg cacctgcctg
     7981 ctcaagcccg tgacgcgctc gctcagcgcc gcgttctccc gttgcataag accagacatc
     8041 gtccgccatt ccgcgaaggc gttctcccac tcgtccagcc ttttcgagta gtcctgctgt
     8101 agctgctcta atgcgctcag caactgtttt tccagctccg tcatgtgcta tttccccgcc
     8161 agtatcatcc agctcgaatc ctctccgaac cgtcccgctt ccgggttcac cctcacgcag
     8221 ctgcgtctct gctcgccgca ggtcgagagc tgcacgccgc tgttccgctc ggacagcatc
     8281 gcctgcgtgc tcttctgctc ccggatggtc gtgtaattgt cgagtatctg ctgactctgc
     8341 caccacagaa tgcccgcgct cgatgcgatc agcaggacgg aaaccaggac gatggtcagc
     8401 cacgtctggc tgaccatacg caccatgcct ttcgtgcgct ggctcatggc tgaggacagc
     8461 ttccggtcgt ggtcgaggat ggcggcgctg attctcttct cgctttcgtt cagttccgct
     8521 ctgacagact gctcgtgctc gctgaatgcg gctttcagca tctcgccggt actctgctgc
     8581 tgcgctttcg atttctgctc taagtccttc gccagcgtta aaagactgct catagatggc
     8641 tccctttagt cggatgtttc gccccccgtc cgggtcggca atgctgatac tgcttttcgt
     8701 ggtgcgtacc acctcaaaac ccgcgttttc cagcgcctca gtaacgtcct gacgggtttt
     8761 cagctccccg gacgaggcta aggccagcaa accccgggtg atcgcctgag ctgcctcctg
     8821 cttcgtttcc ggcagcgcgg acggcgtgac cagcgcccgc cggttttccg gcgcattcgg
     8881 gtcgtgcagc cccagcctgc cgttcacgat ggtctgccag gcatcgatgc gcggacggtc
     8941 agcgcggtcg taatacggct ggagcctttt gccggtcagc agctccgtgt tcgggatcag
     9001 gaagttcagc tccagccgcc ccttgtcctg gtgctccacc cacagcacgc tgtactggtc
     9061 tttatcgagt ccgggcatca gaacacgctc gaagctcgcc atcagttttt cacgctgacc
     9121 gggcggtaag tcctgttcgg caaacgacag caccccggag gtgtactttt tggcgtaggg
     9181 cgaggcgtcg attagctccc ggacttcctc cggtttaccc tgcagaacgc tggcgccgtc
     9241 gcgcttgcgg tcattaccca gcagataatc caccggaccg gcaccgccgc cgcgccctcg
     9301 tgggtgaaat ttaacgatca tcgtcagccc ccttttccag cacagcgtgc cgcaggcgct
     9361 caagtccggc atcaatggcc atcagcgcag cgacaatctg tacgcgatca tgtccggtac
     9421 caccaccggc gttaacctgc cgggcaatct gattgaggtt gtttcccata ccggcaagtt
     9481 gacgaagcaa cgccggcgag atcgacggaa gtttggcggc acgagcaggt ttctcgtcga
     9541 gacacgtctg ccgcatccag gccgcgagct gcttaccgtc gcagcgatcc agcagacgcc
     9601 ggtgctcgtc ttcagttacc catatcgtga gcattttgct gcgtttgtct gccaatccgg
     9661 cctcctgata acgccgggac ggacggggaa ttatttcccg gtcggcgcgg tgttggacaa
     9721 gccgcaggcg cgtcagtgcc ttttagcggg tttcggggcg cagccctgaa ccagtcacgt
     9781 agcgctagcg gagtgtatac tggcttaaaa tgtaacatcg cagaaacatc aagcatagct
     9841 gccacataaa gcaggtgaaa aatgagattc gtatgcgtca gcagaagatg cactgccgga
     9901 gaaatgccgc ttcctcgctc actgactcgc tccgctcggt cgttcggctg cggcgagcgg
     9961 taccggctta cgggcggggc ggaaatttcc tggaagatgc taggaagaaa cttaacaggg
    10021 aagcgataag gccacggcag agccgtt
//
