LOCUS       NZ_EU818711             8944 bp    DNA     circular CON 23-OCT-2023
DEFINITION  Bacteroides uniformis strain BUN24 plasmid pBUN24, complete
            sequence.
ACCESSION   NZ_EU818711
VERSION     NZ_EU818711.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14225296
KEYWORDS    RefSeq.
SOURCE      Bacteroides uniformis
  ORGANISM  Bacteroides uniformis
            Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 8944)
  AUTHORS   Shkoporov,A.N., Khokhlova,E.V., Kulagina,E.V., Smeianov,V.V.,
            Kuchmiy,A.A., Kafarskaya,L.I. and Efimov,B.A.
  TITLE     Analysis of a novel 8.9kb cryptic plasmid from Bacteroides
            uniformis, its long-term stability and spread within human
            microbiota
  JOURNAL   Plasmid 69 (2), 146-159 (2013)
   PUBMED   23201047
REFERENCE   2  (bases 1 to 8944)
  AUTHORS   Shkoporov,A.N., Khokhlova,E.V., Kulagina,E.V., Kafarskaia,L.I. and
            Efimov,B.A.
  TITLE     Sequence analysis of Bacteroides uniformis plasmid pBUN24
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8944)
  AUTHORS   Khokhlova,E.V., Shkoporov,A.N., Kulagina,E.V., Kafarskaia,L.I. and
            Efimov,B.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JUL-2010) Microbiology & Virology, Russian State
            Medical University, Ostrovityanova, Moscow 117996, Russian
            Federation
  REMARK    Sequence update by submitter
REFERENCE   4  (bases 1 to 8944)
  AUTHORS   Shkoporov,A.N., Khokhlova,E.V., Kulagina,E.V., Kafarskaia,L.I. and
            Efimov,B.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2008) Microbiology & Virology, Russian State
            Medical University, Ostrovityanova, Moscow 117996, Russian
            Federation
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/23/2023 01:22:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11
            CDSs (total)                      :: 11
            Genes (coding)                    :: 10
            CDSs (with protein)               :: 10
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 1
            CDSs (without protein)            :: 1
            Pseudo Genes (ambiguous residues) :: 0 of 1
            Pseudo Genes (frameshifted)       :: 1 of 1
            Pseudo Genes (incomplete)         :: 1 of 1
            Pseudo Genes (internal stop)      :: 0 of 1
            Pseudo Genes (multiple problems)  :: 1 of 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            EU818711.2.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8944
                     /organism="Bacteroides uniformis"
                     /mol_type="genomic DNA"
                     /strain="BUN24"
                     /db_xref="taxon:820"
                     /plasmid="pBUN24"
     gene            complement(join(8606..8944,1..183))
                     /locus_tag="HS538_RS00005"
                     /old_locus_tag="CDS_8"
     CDS             complement(join(8606..8944,1..183))
                     /locus_tag="HS538_RS00005"
                     /old_locus_tag="CDS_8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016271957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_008669313.1"
                     /translation="MEKGQESKQKRKTPLTTIAISQEYAKKLDEYLNGTGITRKEFVEL
                     SVDYFQRTGFDLRGEAFDLSPLEKVAGRLEQSAKIMERHNEGTEAVHLLLQAVREQTAK
                     QLPAPELIAHAAEEKAKAEAKSEEQEREIARLRSENSALLEYKEKAYRELCRIRDEQKT
                     IGKIKVNIEL"
                     /name="hypothetical protein"
     gene            complement(297..479)
                     /locus_tag="HS538_RS00010"
                     /old_locus_tag="CDS_9"
     CDS             complement(297..479)
                     /locus_tag="HS538_RS00010"
                     /old_locus_tag="CDS_9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008669316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172683580.1"
                     /translation="MKTGDKVIVPAEINGYGRDLRAIVTEIEKFAGAIFVTVIFTEPCP
                     EACGRRGGVFTMTSS"
                     /name="hypothetical protein"
     gene            complement(493..1470)
                     /locus_tag="HS538_RS00015"
     CDS             complement(493..1470)
                     /locus_tag="HS538_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008669318.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_008669318.1"
                     /translation="MEKKDKKQRDIVLSQDNALTTARYKFDLIEKRALYSIIRNIRAQY
                     IENENGRRDLFDDLIITIHEEELKKCGDNTKMQNIYDALKRLRNRDIEINNEKMWLSIG
                     FVNYVKHIKNKSYFEVQVSKEVLPYYVELAQNFTSYSMTVAIALKSTFSQRFYELCCQY
                     RNAGFFFYTVEKLREMFMLEKKYKRGCDFKRRVLDDPQKELRELYNAGQCDLYFEFEPK
                     SYKGKEVTEYKFYVYTRQTEQQKLLEYESAKQAIIYITTTISRFSKSDKGYVKRVVNAV
                     QLHPEIAVQVAQKIQKKFEQYIDKPAKQIGAIIRVCLMEDFGIE"
                     /name="replication initiation protein"
     gene            complement(1683..1910)
                     /locus_tag="HS538_RS00025"
                     /old_locus_tag="CDS_1"
     CDS             complement(1683..1910)
                     /locus_tag="HS538_RS00025"
                     /old_locus_tag="CDS_1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008669320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_236839309.1"
                     /translation="MRFRSRKLLVLYIKSHIYTKFNTPKNLPNPLHLALLVSTLSHSPE
                     IRRIKKHAEKWSEATSINQKRNTPLLYGNF"
                     /name="hypothetical protein"
     gene            complement(1946..2260)
                     /locus_tag="HS538_RS00030"
                     /old_locus_tag="CDS_2"
     CDS             complement(1946..2260)
                     /locus_tag="HS538_RS00030"
                     /old_locus_tag="CDS_2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851388.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_007851388.1"
                     /translation="MEAKKFYTLEEIEDKYIGEKGTPKRDAYEEELNSFLIGEAIKQAR
                     QSKNLTQEELGNLIGVQRAQISRIENGKNLTFSTIARVFKAMGISAKLEIGSMGKVALW
                     "
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(2266..2613)
                     /locus_tag="HS538_RS00035"
                     /old_locus_tag="CDS_3"
     CDS             complement(2266..2613)
                     /locus_tag="HS538_RS00035"
                     /old_locus_tag="CDS_3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_008669299.1"
                     /translation="MEAKSRFKVKLSNEAQEFLDGLPNKVREKIISNIRKSTFVLDPDL
                     FKKLDDTDIWEFRTFYNKTKYRLLAFWDKDDKINTLVIATHGFIKKTQKTPPKEIAKAE
                     EIRKDYFNSKR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            3005..3610
                     /gene="btgA"
                     /locus_tag="HS538_RS00040"
     CDS             3005..3610
                     /gene="btgA"
                     /locus_tag="HS538_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein BtgA"
                     /protein_id="WP_008669301.1"
                     /translation="MDKETTTSVTIDRKTFARLDRLAKSNNVSKKEFLSCALEYFEKYG
                     INPVEHESPAKEMQKLIKRCDQVIAFIRKQEQDFLRPACEAMGSTSMRVTMSMDSILTE
                     KKFSQYQKDNDLFMRDLASLAGIREQALDRAEKAVGQSRDMLLKNQQAIYARLDAVTQR
                     QEKIFSYIASYIDAKGKAGLFDDIKALYKNEKNKREKI"
                     /name="btgA"
     gene            3607..4485
                     /gene="btgB"
                     /locus_tag="HS538_RS00045"
     CDS             3607..4485
                     /gene="btgB"
                     /locus_tag="HS538_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein BtgB"
                     /protein_id="WP_008669303.1"
                     /translation="MNVKIQGSGNGTYANTGSCVAVTNYLQHEDLERMKKGEEVQPFFN
                     QFRDYVSAREVTFKIDNNKAKLSRTDAKFYVITVSPSEKELRCMGRTPQECAEALRRYI
                     RQDVMRNYAEGFGKGLKSDDVEYYAKIHFNRDGESDSDMHAHIIVSRKDRSNTRKLSPK
                     TNHTGKKNCGNVKGGFDRTDFFRKCESSFDRRMGFDREPEESFDYLNAVKNGSPAEIAR
                     QVERAERIRKEKWDKLKAELQSRQEPEKSKNQQVEKTPDIEQPIPKKKQQEEDLELLKK
                     PKRSRGFGMGM"
                     /name="btgB"
     gene            complement(5040..6695)
                     /locus_tag="HS538_RS00050"
                     /old_locus_tag="CDS_5"
     CDS             complement(5040..6695)
                     /locus_tag="HS538_RS00050"
                     /old_locus_tag="CDS_5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008669305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_080974081.1"
                     /translation="MQKTYLYLMVCVIGAMSLASCSEDSISPDAGGDGDGDSTTEVPLA
                     QVAKPKPNPWLAQEEYSITHFNSAQTDAFSSAVKDGTFNIDLSKCQMTWSGPVNLMTLA
                     STSPNYMWGMSSDRVSYLDISDGKLERVAEAGLPGITMKTQEQLTRIIADHATYDELSK
                     TVTDILGPAPQMSMANGNYVLCDKDNYAYTNAGQVMARYRLANPNNPKDGIMLDHQIRL
                     TNFTFGSFTLVGATMTYDGHLVVAAQNGLLVLNRALTTIEDSYPLPSDQILTNSICIDE
                     NGGVYVASNSRTPGGKGLMQKLICKDGKISTSQADGAWQAYYDGGPQAPCIKLGHGTGS
                     TPTLMGFGQDKDKLVVITDGSKRMKLVAFWRDEIPSDAQQVAGYDKRIAGVHEVTCGLG
                     TSTEWIQSEQSVVVGGYDAFVVNNINVTNQEINDKIIGVIAIGPIVKGPQGAECVRWNT
                     KEKKWESKWTRSDVSSVSMIPAVSIKSEMVFVCGWNDASGWEVTGLDWKSGATRHRSIL
                     GKNNRANGAYAIIQYLANGDLLFNSVAGPIRVKY"
                     /name="hypothetical protein"
     gene            complement(6915..7970)
                     /locus_tag="HS538_RS00055"
                     /old_locus_tag="CDS_6"
     CDS             complement(6915..7970)
                     /locus_tag="HS538_RS00055"
                     /old_locus_tag="CDS_6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781140.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_215424929.1"
                     /translation="MIVMAMLAFFVFVSRYYVTCRNRQFEQSRWMIVVALLLFVVHYMC
                     QMRLGWRQQGNDVGVLFNLLFYSPSAILLSWSQLNILRAGHRRWSFMRYGVVGYALMVL
                     CIVAGVISNGSLHIGPMLYVADAIHFFTLLYYTWAPLRELGNVQRRLDSEHGNPADAYL
                     RTMRFGFFVVCAFAVISPLYILSRPLLFVFGPLGLISLSLFIVSFTALGFSMSEGVTEI
                     VTETNDEIAAAKVFREIGPERIAEIDMAVSKWRSEGGFRDSNLTLSSFARRIMVNRTDV
                     ASYLTSIYGKNFRTWLSGIRVEEAKALMAAHPEYSNEVVSMECGFSSRVYFQRLFKERT
                     GLTPAEWRRQR"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(<8224..8576)
                     /locus_tag="HS538_RS00060"
                     /pseudo=""
     CDS             complement(<8224..8576)
                     /locus_tag="HS538_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005852953.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /name="DJ-1/PfpI family protein"
     Typing          complement(494..1470)
                     /name="rep_cluster_1097"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          3608..4482
                     /name="MOBB"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 agcttcaccc cggaggtcga acccggttct ttggaaataa tcaacggaca actcgacaaa
       61 ttctttgcga gttatacccg taccgtttaa atactcgtct aattttttgg cgtactcttg
      121 gcttatcgct atggtggtaa gcggtgtttt cctcttttgc ttgctttcct gtcctttctc
      181 cattgctgta aaatgctata ttctgttgca aaggtagtta taagtattat tatagcaatt
      241 tatcacagat attattgcaa tttattgcga ttatagcaaa ataaatcacc ttgctattag
      301 ctggaagtca tggtaaacac cccccccctt cttccgcagg cttccggaca tggttcggtg
      361 aatatcactg ttacgaatat tgccccggcg aacttctcta tctctgtaac tattgcccgt
      421 aaatctctgc catagccgtt tatttcggct ggtacgataa ctttatcacc tgttttcata
      481 cttgtatgtt ttttattcta taccaaaatc ttccattaag caaacccgga tgatagcccc
      541 tatctgtttg gctggcttgt ctatatattg ctcaaacttc ttttgtatct tttgcgccac
      601 ctgtacggct atttccgggt gtaactgtac ggcgttcact acacgcttaa catatccttt
      661 gtcactttta gagaacctcg aaatagtggt tgttatgtag atgatcgcct gttttgcgct
      721 ttcgtattcc aatagctttt gttgttcggt ttgccttgtg taaacgtaga atttgtattc
      781 ggtaacttcc ttgcctttgt agctctttgg ctcgaactcg aagtataaat cgcattgtcc
      841 ggcattgtac aactcccgga gttccttttg cggatcgtca agtacacgcc ttttgaaatc
      901 gcatccccgt ttgtatttct tttccaacat gaacatttcc cgaagctttt cgactgtgta
      961 gaaaaagaac ccggcgtttc ggtattggca gcacagttcg taaaaccttt gcgagaatgt
     1021 gcttttgagt gcgattgcta ccgtcatgga gtaactcgtg aagttttggg cgagttccac
     1081 gtaatagggt agtacctctt tggaaacttg cacctcaaaa tacgatttat ttttgatatg
     1141 cttgacgtaa ttgacaaaac cgatacttag ccacattttt tcgttgttaa tctctatatc
     1201 gcgatttcta agccgtttta gcgcatcgta gatgttttgc atcttggtat tgtcaccgca
     1261 tttctttagt tcttcctcgt gtatggtgat aatcagatca tcgaataagt cccgtctgcc
     1321 gttctcgttc tcgatgtatt gcgcccggat atttcgtata atggagtata gggcacgttt
     1381 ttcgataagg tcgaacttgt agcgtgcggt agtcagcgca ttgtcttgcg acaggactat
     1441 atccctctgt ttcttgtctt tcttctccat gactttaatg cttttcgcaa aggaaatatt
     1501 tatctacgac aaaaacaaat atatggcgta gaatatttgt cgtagataac cgtttttttc
     1561 ggaaatttgt cgtagatgct cggaaatttg tcgtagatgc tcggaaattt gtcgtagatg
     1621 acctttgtaa gatattacag cacaatgtgt tatgctatgc cgtaaaagta actaaaaaga
     1681 aactaaaaat taccgtaaag caatggagtg tttctttttt ggtttataga ggtcgcttcg
     1741 ctccactttt cagcgtgttt tttgatacga cgaatttccg gagaatggga gagagtggaa
     1801 acaagtaaag ccaagtgcaa cggattagga agattttttg gcgtgttaaa ttttgtataa
     1861 atatgacttt taatgtataa aacgagaagt ttccgggagc gaaaacgcat cccggattta
     1921 atgtaacttt ttgttgtata gttagttacc ataacgcaac tttacccatg cttccgattt
     1981 caagtttagc acttatcccc atagccttaa aaactcttgc aatggtggaa aaggttaaat
     2041 tcttaccgtt ttcaattcgg gagatttgag cccgttgcac tcctatcaga ttacctaatt
     2101 cctcttgggt taagttcttt gattggcgag cttgtttaat ggcttcacct atcaaaaaag
     2161 aattaagttc ttcttcgtag gcatcacgtt tgggagtacc tttttctccg atgtatttat
     2221 cctcgatttc ttcgagtgta taaaatttct ttgcttccat acgctttatc tttttgaatt
     2281 aaaataatct tttctaatct cttcggcttt ggctatttct ttgggaggtg tcttttgggt
     2341 tttcttgata aacccatgtg ttgcgattac cagagtgttt atcttatcgt ccttatccca
     2401 aaaagcaaga agcctgtact tggttttgtt atagaacgtt ctgaattccc aaatatccgt
     2461 atcatccaat ttcttgaata aatctggatc aagtacaaag gtggatttac gaatattgct
     2521 aatgatcttc tcacgtacct tgttgggcaa tccgtctaaa aactcttggg cttcgttgga
     2581 taatttgacc ttgaatcttg attttgcttc catataaagt tttttagtgt tgcaaagata
     2641 atattttgtt tccatatagc gaaacaaaat attgatattt tatgcagcct gttgtgccgt
     2701 tttgatgtgt ttttttgttt gtggaatagg ttctttcttt gtgcctcgct ccgacttctc
     2761 cccgtccccc ttgtacgagc tttcgccgta ccgcagggga gggtgttcgt cgattgctcg
     2821 gcagtcgaaa gaacagcaag aggaaaccgg gctttaccct gtttttcctc ttgccctacg
     2881 gggttacggc tgaatatcag ccgtttaagt tttttaatcg caattagttt gaaattgtgg
     2941 ttaaaatcat acctttggaa atcagagatt taataatata aacagcaatt aaaaccgcaa
     3001 ttgtatggat aaggaaacca ccacttctgt caccattgac cgaaaaacgt ttgcccggct
     3061 tgataggctg gcaaagtcca ataatgtatc aaagaaagag ttcctttcct gtgcgctgga
     3121 gtacttcgag aagtacggca tcaacccggt tgagcatgag agtccggcaa aggaaatgca
     3181 gaaacttatc aaacgctgtg atcaggtgat agcgttcatc cggaagcagg agcaggattt
     3241 cttgcgtccg gcttgtgaag ccatgggcag tacaagtatg agggtgacca tgagcatgga
     3301 ctcgatactt acggaaaaaa agttcagcca ataccaaaaa gacaatgacc tattcatgcg
     3361 tgaccttgca agccttgccg ggataaggga gcaggctttg gaccgggcgg aaaaggcagt
     3421 cggtcagtcg agggatatgc ttctgaagaa ccaacaagcc atttatgcaa ggctggacgc
     3481 tgtgacgcaa aggcaggaga agatcttctc ctatatcgca agctatatcg atgcgaaagg
     3541 aaaagccggg cttttcgatg atataaaagc cttgtacaag aacgagaaga acaaaaggga
     3601 aaagatatga acgtgaagat acagggaagc ggtaacggca catatgccaa tacaggcagt
     3661 tgtgttgcgg tgacgaacta tctccagcat gaggatttgg agaggatgaa gaaaggggag
     3721 gaggtgcagc cgttcttcaa ccagttccgg gactacgtga gcgcaaggga ggtcacattc
     3781 aagatagaca acaacaaggc taagttaagc cggactgacg caaagttcta tgttatcact
     3841 gtcagccctt cagagaagga gctgcgctgc atgggcagaa ctccgcagga gtgtgcggaa
     3901 gccttacggc ggtacatacg gcaggatgtg atgagaaact atgcggaggg cttcggaaaa
     3961 ggcttgaaaa gcgatgatgt ggaatattat gcaaagatcc atttcaaccg ggacggtgaa
     4021 agtgacagcg atatgcacgc acatatcatc gtcagccgga aagaccggag caacaccagg
     4081 aagttaagcc ctaaaacgaa ccacaccggg aagaagaact gcggcaacgt gaagggaggt
     4141 tttgaccgga cggatttttt ccggaagtgt gaaagctctt ttgatcggcg catggggttt
     4201 gaccgggagc cggaggaaag cttcgactat cttaatgccg tcaagaacgg aagtccggcg
     4261 gaaatagccc ggcaggtgga acgtgcggaa cgcatcagaa aggagaaatg ggacaaactc
     4321 aaagcagagc ttcaatcccg gcaggagccg gagaagtcga aaaatcaaca ggtggagaaa
     4381 acgccggaca tcgagcagcc tattcccaaa aagaagcagc aggaggaaga tctggaactc
     4441 ctgaagaagc caaaaaggag cagaggtttc ggaatgggca tgtgattttt ctattttccg
     4501 gcacaaaggt aactccgcac gccgcatttg taaagggacg tttcactctc cgggtaaaaa
     4561 atctcctgtg ctcgcttcgc tcgtgcggta ttttttaccc ttcgcccttg acaaatacac
     4621 tgtgcttcgc tggaaggtgt ttaggaaaaa agaaaaaaat gttgttcttt ggtgagtgtc
     4681 cgttttgtca ttttgttacc gggatttgtc cgcatggtgg aggaactgcc ccgatcagtt
     4741 aggcacgtaa tatcgttttg taatagtcgg tggtctgttt tatggtatac gctccgatat
     4801 cgctttcttt ttgcttttta tatgtgcaaa ggtcaaaagc ccccagcgaa aaccccgccg
     4861 gaggcttgtt ataatctgtt tcttatctgt tatttatcac ctgtatctag gaataaagaa
     4921 cagaagcctt gtttatggaa ctgatagaac atttcaatat gttcgggtgt gtcattacaa
     4981 tacttcggta attttttagt gaagtattga cataactgtt atatgatgat taaattatct
     5041 caatatttta cgcggattgg tccggcaaca gagttgaata aaaggtcgcc gttagcaaga
     5101 tactgaatga tggcgtaggc accattggct cggttgttct tgcccaatat gctgcggtga
     5161 cgtgtggcac cactcttcca gtcaagtcct gtaacttccc agcccgaagc atcgttccag
     5221 ccacatacaa ataccatctc tgacttgata cttacggcag gaatcatact tacagaactt
     5281 acatcgctgc gcgtccactt actctcccac tttttctcct ttgtattcca acgtacacac
     5341 tcggcacctt gagggccttt gacaatagga ccaatagcga ttacaccaat aatcttgtcg
     5401 tttatttcct gattggtaac attaatattg tttacaacaa aggcgtcata gccgcctact
     5461 acaacagact gctcagactg tatccactct gttgatgttc caagaccaca tgtaacctcg
     5521 tgcactccgg ctatacgctt gtcgtatcct gccacttgct gtgcgtctga ggggatttcg
     5581 tcacgccaga aagctaccag tttcatacgc ttagagccat cggtaataac taccagcttg
     5641 tccttgtctt ggccaaagcc cataagtgta ggcgttgaac cagtgccatg tccgagtttg
     5701 atacatggtg cttgcggacc accgtcgtaa taggcttgcc atgcaccatc agcctgggag
     5761 gtggagattt tgccgtcctt gcagatgagt ttctgcataa ggccttttcc gcctggtgtg
     5821 cggctgttac ttgctacgta aacaccgcca ttctcgtcga tgcagataga gttggtgaga
     5881 atctggtctg atggaagagg gtatgaatct tcgattgtag taagagcacg attcagcaca
     5941 agaagtccgt tctgagcagc cacaacaagg tgtccgtcat aggtcatagt agcgcctacg
     6001 agtgtaaaag agccgaaggt aaaattcgta agtcttatct gatgatccaa catgatacca
     6061 tccttgggat tattaggatt ggcaaggcga tagcgtgcca ttacctgacc tgcattggtg
     6121 taagcatagt tatccttgtc gcacaagaca taattaccgt tggccataga catttgtggc
     6181 gccggaccca atatatcggt aaccgtcttg gaaagttcgt cgtaagtagc atgatcggca
     6241 attatacgtg tcagttgctc ctgggtcttc attgtaatcc ctggcaagcc agcctcggca
     6301 accctttcaa gtttgccgtc gcttatgtca agatacgaca cgcggtcgct actcataccc
     6361 cacatataat tgggcgaagt cgaagcaaga gtcatcaaat taacaggacc gctccatgtc
     6421 atctgacact tggaaagatc gatattgaaa gttccatcct tgacagcaga cgagaaagca
     6481 tcagtctgag ccgaattgaa gtgcgtaata ctatactctt cctgtgcaag ccaagggtta
     6541 ggtttgggtt ttgcaacttg tgccaaaggc acttcggtag tgctgtcgcc atcgccatcg
     6601 ccaccagcat caggagaaat agaatcttcg gaacacgaag ctaaagacat agcccctatg
     6661 acacacacca ttaaataaag ataggttttt tgcatagtga attgtttttg agaatttata
     6721 tttgaatagt ttgaatttcc tcatgcaaag atacaggagc atcaaccatc aaaaacctca
     6781 aagacatcac ttgtgtgtca ctcttataga aaggatacgt cacagtaaga aaggttacac
     6841 tttgccttat tatgtaacct tcgtacaaaa gttacacctt acattcagta gcaaacgcac
     6901 acataaccag tatattaccg ttgacgtcgc cactcggcgg gagtcaagcc cgtcctttcc
     6961 ttgaacagac gctgaaaata cacacgcgac gagaaaccgc actccataga aacaacctcg
     7021 ttactatatt cggggtgtgc agccatgagt gcctttgcct cctccacgcg aatacccgaa
     7081 agccatgtac ggaaattctt accatatatg gaagtcagat acgaagcaac gtcggtacga
     7141 ttaaccatta tgcgacgagc aaacgaggat aatgtcaagt tgctatctct aaaaccgccc
     7201 tcgcttcgcc atttgcttac cgccatatct atttcggcaa tacgctcagg cccaatctcc
     7261 ctaaagactt tagcagcggc tatctcgtcg ttagtctcgg taacaatctc agttactccc
     7321 tcggacatac taaatccaag cgccgtaaaa ctaacaataa acagcgaaag cgaaatcaat
     7381 cccaaaggtc caaagacaaa gagcagcggc cgcgacaata tataaagagg cgaaattaca
     7441 gcaaaagcac acaccacaaa aaaaccaaag cgcatagtgc gcaggtaggc atctgcagga
     7501 ttaccatgtt cactgtcgag ccgacgttga acattaccaa gttccctcag cggtgcccat
     7561 gtataataca atagagtaaa gaaatgaata gcatcagcaa catatagcat aggaccaata
     7621 tgcagactgc catttgaaat aacacctgcg actatgcaca ataccataag agcatatcca
     7681 acaacgccat agcgcataaa actccaacgt ctatgcccag cgcgcagaat attaagctgc
     7741 gaccatgaca acaaaatagc cgaaggcgaa taaaacagca gattaaacag aacacccaca
     7801 tcgttcccct gttgtcgcca acccaaccgc atctgacaca tgtagtgtac aacaaacaat
     7861 agtaatgcca caacaatcat ccaacgcgac tgctcaaact gtctgttacg gcaagttaca
     7921 tagtagcgcg acacaaacac aaaaaatgca agcatggcca tcacaatcat gcaagtatat
     7981 tgaagagcaa taaggtctaa gcaagtatcc aagattgtat gtatattaaa taatttaacg
     8041 tgagttcgac gaaatataag tgcctgaaaa atggtgatta gcgaaaaatt gttgtaatct
     8101 tagagtgtta aatatcaaaa gtttacagac aataattgct atgattaccg aggacaaagt
     8161 tactgagatt ttctgtatta cggatgactt ctgcaaagtt tttgatgttg tttctcggtc
     8221 aataccacac ttagccatga atgaagctgc attacaaatc gcacctataa ccttttcttg
     8281 ttcaatagca cttttaataa ttggcataac cttttctgca acaggtgtat tccaaccaaa
     8341 accgccaatt aataccaatg ctacataatc atcaggcatt gtgtcaaacg aataatcggg
     8401 taatgtgcgg aatccaccaa tcgaacttat tggttctaag gtgggtgcga caaccttatt
     8461 gacatatttt ggattttttt catggcaaaa tcatcagctg taatagcctg tgaaaagtac
     8521 acagcttcat gtgctgcata atccggcaaa aggataaata aataaaattt ctttattcat
     8581 gattttttta tttataaatg ttcttttata actctatatt tacttttatc ttccctatgg
     8641 ttttttgttc atcacgtatc cggcatagtt cccggtatgc cttttctttg tactccagca
     8701 aagcggagtt ttcggagcgc agccgggcaa tctccctttc ttgttcttcg cttttggctt
     8761 ctgcctttgc tttttcttcg gcagcatggg cgatcagttc cggcgctggg agttgcttgg
     8821 cggtctgttc ccggacagct tggagaagca ggtgcaccgc ttccgtcccc tcgttgtgtc
     8881 gttccatgat ctttgcggat tgttccagcc gcccggcaac cttttctaat ggggagaggt
     8941 caaa
//
