LOCUS       NZ_CP154427            23941 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Klebsiella pneumoniae strain Kp387 plasmid p387-4, complete
            sequence.
ACCESSION   NZ_CP154427
VERSION     NZ_CP154427.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN41106963
            Assembly: GCF_039515315.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 23941)
  AUTHORS   Hong,H. and Liu,Y.
  TITLE     cefiderocol resistance in Carbapenem-Resistant Klebsiella pneumoniae
            in China before its approval
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23941)
  AUTHORS   Hong,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-APR-2024) Department of Clinical Microbiology, First
            Affiliated Hospital of Nanchang University, Nanchang University,
            Nanchang, Yong wai zheng jie No.17, Nanchang 330006, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 375.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_039515315.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 08:11:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,041
            CDSs (total)                      :: 5,917
            Genes (coding)                    :: 5,719
            CDSs (with protein)               :: 5,719
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 79 of 198
            Pseudo Genes (incomplete)         :: 129 of 198
            Pseudo Genes (internal stop)      :: 27 of 198
            Pseudo Genes (multiple problems)  :: 36 of 198
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP154427.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23941
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Kp387"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p387-4"
                     /geo_loc_name="China:Nanchang"
                     /collection_date="2021"
     gene            complement(join(23710..23941,1..140))
                     /gene="tolA"
                     /locus_tag="AAIB08_RS30065"
                     /old_locus_tag="AAIB08_30065"
     CDS             complement(join(23710..23941,1..140))
                     /gene="tolA"
                     /locus_tag="AAIB08_RS30065"
                     /old_locus_tag="AAIB08_30065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            complement(414..659)
                     /locus_tag="AAIB08_RS30070"
                     /old_locus_tag="AAIB08_30070"
     CDS             complement(414..659)
                     /locus_tag="AAIB08_RS30070"
                     /old_locus_tag="AAIB08_30070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            1304..2791
                     /gene="ltrA"
                     /locus_tag="AAIB08_RS30075"
                     /old_locus_tag="AAIB08_30075"
     CDS             1304..2791
                     /gene="ltrA"
                     /locus_tag="AAIB08_RS30075"
                     /old_locus_tag="AAIB08_30075"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_004178082.1"
                     /translation="MMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
                     /name="ltrA"
     gene            2896..4581
                     /locus_tag="AAIB08_RS30080"
                     /old_locus_tag="AAIB08_30080"
     CDS             2896..4581
                     /locus_tag="AAIB08_RS30080"
                     /old_locus_tag="AAIB08_30080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            4591..4848
                     /locus_tag="AAIB08_RS30085"
                     /old_locus_tag="AAIB08_30085"
     CDS             4591..4848
                     /locus_tag="AAIB08_RS30085"
                     /old_locus_tag="AAIB08_30085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            4933..5082
                     /locus_tag="AAIB08_RS30090"
                     /old_locus_tag="AAIB08_30090"
     CDS             4933..5082
                     /locus_tag="AAIB08_RS30090"
                     /old_locus_tag="AAIB08_30090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            6566..8530
                     /locus_tag="AAIB08_RS30095"
                     /old_locus_tag="AAIB08_30095"
     CDS             6566..8530
                     /locus_tag="AAIB08_RS30095"
                     /old_locus_tag="AAIB08_30095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_071177727.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            8530..9261
                     /gene="mobC"
                     /locus_tag="AAIB08_RS30100"
                     /old_locus_tag="AAIB08_30100"
     CDS             8530..9261
                     /gene="mobC"
                     /locus_tag="AAIB08_RS30100"
                     /old_locus_tag="AAIB08_30100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            9268..9798
                     /locus_tag="AAIB08_RS30105"
                     /old_locus_tag="AAIB08_30105"
     CDS             9268..9798
                     /locus_tag="AAIB08_RS30105"
                     /old_locus_tag="AAIB08_30105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(9825..10004)
                     /locus_tag="AAIB08_RS30110"
                     /old_locus_tag="AAIB08_30110"
     CDS             complement(9825..10004)
                     /locus_tag="AAIB08_RS30110"
                     /old_locus_tag="AAIB08_30110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(10030..10458)
                     /locus_tag="AAIB08_RS30115"
                     /old_locus_tag="AAIB08_30115"
     CDS             complement(10030..10458)
                     /locus_tag="AAIB08_RS30115"
                     /old_locus_tag="AAIB08_30115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(10622..10936)
                     /locus_tag="AAIB08_RS30120"
                     /old_locus_tag="AAIB08_30120"
     CDS             complement(10622..10936)
                     /locus_tag="AAIB08_RS30120"
                     /old_locus_tag="AAIB08_30120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(10924..11202)
                     /locus_tag="AAIB08_RS30125"
                     /old_locus_tag="AAIB08_30125"
     CDS             complement(10924..11202)
                     /locus_tag="AAIB08_RS30125"
                     /old_locus_tag="AAIB08_30125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            complement(11377..11742)
                     /locus_tag="AAIB08_RS30130"
                     /old_locus_tag="AAIB08_30130"
     CDS             complement(11377..11742)
                     /locus_tag="AAIB08_RS30130"
                     /old_locus_tag="AAIB08_30130"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            complement(11739..12110)
                     /gene="tolA"
                     /locus_tag="AAIB08_RS30135"
                     /old_locus_tag="AAIB08_30135"
     CDS             complement(11739..12110)
                     /gene="tolA"
                     /locus_tag="AAIB08_RS30135"
                     /old_locus_tag="AAIB08_30135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            complement(12384..12629)
                     /locus_tag="AAIB08_RS30140"
                     /old_locus_tag="AAIB08_30140"
     CDS             complement(12384..12629)
                     /locus_tag="AAIB08_RS30140"
                     /old_locus_tag="AAIB08_30140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            13274..14761
                     /gene="ltrA"
                     /locus_tag="AAIB08_RS30145"
                     /old_locus_tag="AAIB08_30145"
     CDS             13274..14761
                     /gene="ltrA"
                     /locus_tag="AAIB08_RS30145"
                     /old_locus_tag="AAIB08_30145"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_004178082.1"
                     /translation="MMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
                     /name="ltrA"
     gene            14866..16551
                     /locus_tag="AAIB08_RS30150"
                     /old_locus_tag="AAIB08_30150"
     CDS             14866..16551
                     /locus_tag="AAIB08_RS30150"
                     /old_locus_tag="AAIB08_30150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            16561..16818
                     /locus_tag="AAIB08_RS30155"
                     /old_locus_tag="AAIB08_30155"
     CDS             16561..16818
                     /locus_tag="AAIB08_RS30155"
                     /old_locus_tag="AAIB08_30155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            16903..17052
                     /locus_tag="AAIB08_RS30160"
                     /old_locus_tag="AAIB08_30160"
     CDS             16903..17052
                     /locus_tag="AAIB08_RS30160"
                     /old_locus_tag="AAIB08_30160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            18536..18682
                     /locus_tag="AAIB08_RS30165"
                     /old_locus_tag="AAIB08_30165"
     CDS             18536..18682
                     /locus_tag="AAIB08_RS30165"
                     /old_locus_tag="AAIB08_30165"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_232254649.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFSGYRPVF
                     RSG"
                     /name="hypothetical protein"
     gene            18699..20501
                     /locus_tag="AAIB08_RS30170"
                     /old_locus_tag="AAIB08_30170"
     CDS             18699..20501
                     /locus_tag="AAIB08_RS30170"
                     /old_locus_tag="AAIB08_30170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_255074406.1"
                     /translation="MRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARR
                     HVWNYAYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWC
                     AGGLVAGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEP
                     VPVNALADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATN
                     ALIRCVRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYAL
                     KNLLVAGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDV
                     KGLITKLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQI
                     IIARDEFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDL
                     PADFVKTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGD
                     SFIQKEARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTD
                     PLAEYLPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            20501..21232
                     /gene="mobC"
                     /locus_tag="AAIB08_RS30175"
                     /old_locus_tag="AAIB08_30175"
     CDS             20501..21232
                     /gene="mobC"
                     /locus_tag="AAIB08_RS30175"
                     /old_locus_tag="AAIB08_30175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            21239..21769
                     /locus_tag="AAIB08_RS30180"
                     /old_locus_tag="AAIB08_30180"
     CDS             21239..21769
                     /locus_tag="AAIB08_RS30180"
                     /old_locus_tag="AAIB08_30180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(21796..21975)
                     /locus_tag="AAIB08_RS30185"
                     /old_locus_tag="AAIB08_30185"
     CDS             complement(21796..21975)
                     /locus_tag="AAIB08_RS30185"
                     /old_locus_tag="AAIB08_30185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(22001..22429)
                     /locus_tag="AAIB08_RS30190"
                     /old_locus_tag="AAIB08_30190"
     CDS             complement(22001..22429)
                     /locus_tag="AAIB08_RS30190"
                     /old_locus_tag="AAIB08_30190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(22593..22907)
                     /locus_tag="AAIB08_RS30195"
                     /old_locus_tag="AAIB08_30195"
     CDS             complement(22593..22907)
                     /locus_tag="AAIB08_RS30195"
                     /old_locus_tag="AAIB08_30195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(22895..23173)
                     /locus_tag="AAIB08_RS30200"
                     /old_locus_tag="AAIB08_30200"
     CDS             complement(22895..23173)
                     /locus_tag="AAIB08_RS30200"
                     /old_locus_tag="AAIB08_30200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            complement(23348..23713)
                     /locus_tag="AAIB08_RS30205"
                     /old_locus_tag="AAIB08_30205"
     CDS             complement(23348..23713)
                     /locus_tag="AAIB08_RS30205"
                     /old_locus_tag="AAIB08_30205"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     BGC             1..21551
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(5186..5764)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(17156..17734)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          8531..9258
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.37e-140"
     Typing          20502..21229
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.37e-140"
ORIGIN
        1 ttgatggccg cagcgtagct actgatttta gatgacttat ccagagtata aattttcggc
       61 ggctgggtgg tggaatgctt acaggccgtc aggagtaagg ggctgcacaa tgccagcagg
      121 ataaagggta ttaaacgcat cgggttgatg acctgtcagt aaaaaatgtt acatgtatat
      181 ttgtcactct ttacggccac gttcatttac ataaacacgg cttatcgtat cgtttttaca
      241 ccaaacggcc cgccatgcag ttgcgtgcat aggcatgcag cgggttacaa tttaccgggc
      301 gcgtttccgg cggttttccg ggtggtttgt tgcctgtttt atcccgtagc cgccggaaac
      361 gccctcagac cgtctgagcg gtgcgggcaa tgcgacgtta tggtaaatac cccttaccgg
      421 cggcgctgtg gctgccaggt gaaggtggtt tccgtagcct cgtatttctc ccgacgcatt
      481 tcctgcgccc gcctggcttc acgttcgtcc tgaatggcac gaagcaccct ttcccgcacc
      541 tgttgtttta ccgcctttgg cagcgttttg ttccctttca ggcccatggc cagtgcctga
      601 gcgacaaagg cgtccgccag gcgcttttct tcagcgggag tcagtttcag gtgcgtcata
      661 gtggcctccg ggcgtctcag gtttcccgaa cagtttaacc gcaggtcctc tcctcatgcc
      721 agttagcttt cagatgtgtc tataccatct gaaatgtaag tgtgatgaat gtcttaaata
      781 ataaaatttg ttgccatgag aaattttcgg gaaaagacgc gatctgctta caggtggctc
      841 cgggcgcttt tttgtgcctg aagatgagaa ctaatctcat atattgacac ctgaaaacgg
      901 gaggagtaag gtaataatta tactgtgtat atgtacagtg tgtgccggga gaccggttag
      961 agatcaaggg gtgaaagtcc ccgaccattg aaggaccagc aatccacaag gtccccgagt
     1021 catgcgttgc ataccgcgag gtatggggcg aagcgttgac aggggtgttg acaggccagc
     1081 cattgagcca cgaaatgtat attaaattac cgggtgccga cgttgtactg ttaacggaag
     1141 gcaacatcat agggtgcgac actgcgagtg ccacatggac ccggcggggt ctgagaccct
     1201 ggcatgtcaa tacgatctct acgcgggaac cgggagatct cccctctgac catctgccag
     1261 tgtcggagat ggcccgcacc gggaagacga ggagtcatag ccggtgatgt acggagagga
     1321 gaagtcggac tcgctcatag tagcggcgaa gcaggcgaac aacccgaaag gagcggagtc
     1381 agtggagcga aggagcgggg ccaaggggaa cgcggaacag ccacacatgc gccggacaca
     1441 gagccgggaa agcatgtcac agaggctgtc acgcgtgcgg gaagctgcga agcagcggaa
     1501 gaaagaacgg tttacagcat tgttccacct gctgacagtc gaagcactgg aagccgcatt
     1561 cctctccctg agcaggaaag cggccgccgg agtggatggc atcaggtgga tggactacgc
     1621 cggaaacatg aagaacaaca taacagatct gcaccggagg ctacatcagg gcagctacag
     1681 ggcgcagccc ggcaggcgtc actacatccc aaaagcggat ggaaaacaac gcccgctcgg
     1741 catcgcctcg ctggaggaca agatcgtcca gtatgcgctg gtgaaaatcc tgaacgcagt
     1801 ctatgaaaac gactttatgg ggttctcata cgggttcaga cccgggcgaa gccagcacga
     1861 tgcactggac gcactggcca cagggctggt acgcactaac gtaaactggg tactggatgc
     1921 cgacatcagt cagttcttcg acagggtgag ccacgaatgg ctgatcaggt tcacagagca
     1981 tcggatcggc gaccggaggg taatcaggct catacgtaag tggctcacag ccgggacgtc
     2041 ggaggagggt caatggcgag caacggagga aggcacccca cagggtgcgg tcatctcacc
     2101 gctgctggca aacatatacc tccactacgt cttcgatctg tgggcgcatc agtggcgacg
     2161 tcgctatgcc acaggcaatg tggtaatggt cagatacgcc gatgacatcg tcatcgggtt
     2221 cgacaaacga tacgatgccc ggcgcttccg tatagccatg cagcgcagac tgagggagtt
     2281 cggactcacg gttcacccgg agaaaacccg tctgatggag ttcggccgct tcgctgccga
     2341 aaaccgtgcc atcaggggaa aaggcaaacc agaaacgttc aacttcctcg ggttcacgca
     2401 catcagcggg aaagatcgca acggcaggtt catgctgata cgaaagaccc gccgggatcg
     2461 gatgacggca actctgaaag ccatcaaaga cggtctgcga aggcgctggc attactcaat
     2521 ccccgaacag ggaaaatggc tcaggagagt ggttcaggga tacctgaact atcactcggt
     2581 accgggcaac ttccccacca tgcagaagtt caggacacac gtaacaaacc tctggcgccg
     2641 ggcgctcagg cgcaggagcc agaaggatga tacgacctgg acgaaagcaa acaaactggc
     2701 agccgcatgg ctaccaaggg ttcgggttct tcatccatgg cctgtggagc ggttcaccgc
     2761 cagacacccg aggcaggagc ccggtgcgta aatcgcgcac gccgggatct gtgcgggggg
     2821 tatccggtaa cgggtatccc taccgcgaca tgttggcttt aatttattgt tttaaatgtc
     2881 aaagaggaaa acggtatgag tggtggagac ggtcgaggtc cgggtaattc aggtctggga
     2941 cataatggtg gtcaggccag tgggaatgtg aacggtacgt ctggtaaagg tggcccttca
     3001 tcaggtggtg gtacggatcc aaacagcggg ccgggctggg gtacgacgca tacgccgaat
     3061 ggagatattc ataactataa tccgggggag tttggtaacg gcgggagtaa acccggtggt
     3121 aatggtggta acagcggcaa tcatagcggt agctctggtg gcggacagtc ttcggccact
     3181 gcgatggcct tcggtctgcc tgccctggct actccggggg ctgaaggact ggctttatca
     3241 gtttccggcg atgcgttgtc ggccgccgtt gctgatgtgc tggctgccct gaaggggccg
     3301 tttaagtttg gtctgtgggg gattgcgatc tacggtgtgc tgccttctga gattgcaaaa
     3361 gatgatccga aaatgatgtc aaaaattatg acgtcattac cggccgatgc ggtgacggag
     3421 actccggcaa gtactttacc actggaccag gcgacggttc gtgtcagaca acgggttgtg
     3481 gatgtggtga aggatgagcg gcagcatatt gcggttgtcg caggtcggcc aatgagtgtc
     3541 cctgtggtgg atgcgaaacc gacaaaacgt ccgggggtat tcagtgtgtc gattccgggt
     3601 ctcccgtctc tgcaggtgag cgtaccgaaa ggtgttccga cagcgaaagc cccgccaaaa
     3661 ggcattgttg ctgaaaaagg tgattcacgt ccggctggtt ttacagccgg tggtaactcc
     3721 cgtgaggccg ttattcgttt cccgaaagag accggacaga agccggttta tgtgtcggtg
     3781 acagatgttc ttaccccggc acaggtaaaa cagcgtcagg aggaagaaaa gcgtcgccag
     3841 caggcatggg acgccgctca tccggaagag gggctgaaaa gagactatga taaagcgaaa
     3901 gctgagctgg atgccgaaga taaaaatatt gcgaccttaa acagccgcat tgcatcgaca
     3961 gagaaggcgc tccccggtgc aagggctgct gttcaggaag ccgataaaaa ggtaaaagag
     4021 gcagaggcaa ataaagatga ttttgtgact tataacccgc ctcatgaata tggctccggg
     4081 tggcaggatc aggttcgcta tcttgataag gatattcaga atcagaatga gaaattaaaa
     4141 gcggctcagg catctttaaa cgcaatgaat gaatccttat ccagagataa ggctgcactt
     4201 accggggcga tggagagccg gaaacaaaag gagaaaaaag cgaaggatgc agaaaataag
     4261 ttaaatgagg aaaagaacaa gcctcgcaag gggactaaag actacggcca tgattatcat
     4321 ccagtaccta aaacagaaga cataaaggga cttggagagt taaagcgagg tgatcctaaa
     4381 acacctaaac aaggtggtgg tggtaagcgg gcccgatggt atggcgataa aaaacgtaaa
     4441 atttatgaat gggattccca gcacggtgag cttgaagggt atcgtgccag tgatggcgaa
     4501 cacctaggcg catttgatcc caaaacgggt aagcaggtta aagggccaga tccaaaacgg
     4561 aacattaaaa aatatctttg agaggtaaat atggggctta aattacgttt gacatggttt
     4621 gataagaaaa ctgaagagtt taaaggggaa gagtattcta aagactttgg tgacgatggt
     4681 tctgtcattg aaagcttggg aatgccttta aaggataata ttaataatgg tgagtttgat
     4741 ttgaagaaag aatgggttcc tttactacag ccatttttta aaaatcaaat aaaacctgat
     4801 gtggataatt gttatatagc ttttgattat cgggacggta actggtaaca aaaaattatc
     4861 aaggatgatt tgaaatactg acttccggtg ttcagggatg aatgccggag tctttaaata
     4921 cagggaaagt atatgaaaaa ggtaaagact atttttcttt ttatattgat tgttgctggc
     4981 tttcttctgg ccgcatgtca ggcaaattat atccgggatg ttcagggcgg aacggtggca
     5041 ccatcgtcct cctctgaact gacggggatc gcggttcagt agaaaagatc aaaggatctt
     5101 cttgagatcc tttttttctg cgcgtaatct tttgccctgt aaacgaaaaa accacctggg
     5161 gaggtggttt gatcgaaggt taagtcagtt ggggaactgc ttaaccgtgg taactggctt
     5221 tcgcagagca cagcaaccaa atctgtcctt ccagtgtagc cggactttgg cgcacacttc
     5281 aagagcaacc gcgtgtttag ctaaacaaat cctctgcgaa ctcccagtta ccaatggctg
     5341 ctgccagtgg cgttttgcgt gctttcccgg gttggactca agtgaacagt taccggataa
     5401 ggcgcagcag tcgggctgaa cggggagttc ttgcttacag cccagcttgg agcgaacgac
     5461 ctacaccgag ccgagatacc agtgtgtgag ctatgagaaa gcgccacact tcccgcaagg
     5521 gagaacggcg gacaggtatc cggtaaacgg cagggtcgga acaggagagc gcaagaggga
     5581 gcgacctacc ggaaacggtg gggatcttta agtcctgtcg ggtttcgccc gtactgtcag
     5641 attcatggtt gagcctcacg gctcccacag atgcaccgaa aaagcgtctg tttatgtgaa
     5701 ctctggcagg agggcggagc ctatggaaaa acgccaccgg cgcggccctg ccgttttgcc
     5761 tcacatgtta gtcccctgct tatccacgga atctgtgggt aactttgtat gtgtccgcag
     5821 cgcccgccgc agtctcacgc ccggagcgta gcgaccgagt gagcgaggag gcgcaatttc
     5881 cccggcacct gcaagacggt caccggacgc gctgatgtgg gatattgtcc cctgattaag
     5941 tctttctatt ccctgacgat caattatcag gataggtgaa ccatgtcggt ttttcgctga
     6001 acattttacg ttaacctatc tctgttgctt ttttctcctt gcggagaaat gcaagtcatc
     6061 cccgctgggg cgtggctgac ttcaggggaa aagaccttgc ttacgctggc tggacgccac
     6121 cgacgcacgg tcttttcccc tctttctggc tctgtccggc tggacgccgg ccacgccaga
     6181 aattcacccg gcccccgtca ggctcacgcc tgaccaccca caaaaatcca cggtgctgga
     6241 cgcacctgac gaagcagcaa agctgctcct gattttgcgg gtggtcagcc gctcgctatg
     6301 gcgaactctg acgggggccg gaacaccgga aaagaccgca ctggggtgcc gccttttcct
     6361 ctcacacgct ggggcgtgct cgttgttcct ccggggctgc gccttttccg catggggcgg
     6421 aaagaggctg gcctccgcgg tgaaagctga acgcaatcac cacggacgtg accgccgccg
     6481 ccatgccttg gggcatgtcc gcggcttgtg cagcgggggc tgcgcatcac gccggtaaac
     6541 ccgtcgtctg aaggagagag attgcatgtt taatacggat tcgcttgcct ggcagtggca
     6601 tatcccggag ctggcccggc agatttaccc gtgggtcagc tggctgtacc gggagtatta
     6661 cagtctggcc ggtttttttc tggttatcgg cctgtttttc ggtctggctg aactctgggc
     6721 cggccgaatg cgttttgtgg ggctgagcca taaggcgcgg cgggagtatg ccgatcgcta
     6781 taagcgcgat aataaccgga ctgtgccatt ttcggtgctg gcctcgctgg attcacccgg
     6841 gcggatggtc agggcacggc gacatgtctg gaactacgcg tactggctga ccggcgctgc
     6901 cggtctggcc cttctggggg ggctggttgt cgccgtgttt atcgagagct ggggagaaac
     6961 cgtcctgcgc ccggacctct atgcgaacgc agattattac ctgctgcagc cggctaacct
     7021 gttcgggata gcctggtgtg ccggagggct tgtcgccggc gtccttctgg cgcggctgct
     7081 ggcgttcctg ctgcttgatg gtcattttgc ggccgctgac gaggcggtga acgcgaaact
     7141 gaatcaggag agccggcgca gcagccagcg gaccggagaa atgacagacg tccgccacct
     7201 gcatttcggg gagccggtac cggttaacgc gctggccgat ttttccacgg agcaggcccg
     7261 gaaacagcag gcggtgtttc tgggtaagga tgagcagggc cagccggtgc tggtccctcg
     7321 tgatacctgg cgcaagacca atattcagat cctcggcctg cccgggagcg gcaagagcgc
     7381 gatggccacc aacgcgctca ttcgctgcgt acgcgatttc ggggacgctg tggtgtactt
     7441 cgaccccaaa ggggacgcgt gggcgccgca cgtcttccgg gcgcactgcc cggacttcac
     7501 cctgctggat ctgcggccgg ggaaaccggc gcagctgaat ctgttccgcg atctcgacca
     7561 gtacgccctg aagaatctgc tggttgccgg gtttaacctg agtgagaccg gcgacgtggc
     7621 ggaccactac cgcatcagcg agcagaaagc ggcgaagctg attgcggagc agttcccgca
     7681 gggggcaaac attcagcagg tgctggcggc ggcgtacgcg ttgccggagg ccctgaaaaa
     7741 ggacgtgaag gggctgatca ccaagctgga gaacgtggcc gacctgagcg tcctgcagac
     7801 ggacagcggt atcgatgtgg cggggataat caacggcggc ggctgcctgt acgtcatcgg
     7861 ctcgatggac gatgaggcgg tgatccgggt gcagaagatg ctgtttgccc gctgcgcgca
     7921 aatcatcatt gcgcgggatg agttccggag gtggccgcac gcgagcatca tgctcgatga
     7981 gattaaatat ctgctgtcga agtacgtgct gaacgcgctg gggacgctgc gcagccggga
     8041 ctgcaacctg ctgctcgcgc accagtcgct gggcgacttc ggtcagtgcg ggcaggatct
     8101 gcccgctgat tttgtgaaaa ccacggtact ggataacacg ccgatccgct ggttctatcg
     8161 cgcggccagc caggagtccg cgcagtgggc ggcgggccag accggggaga tccgggtgga
     8221 cgtggagcgc cgccgggcca gccgggaggc ggggaacgtg gagcacatca gcggcgacag
     8281 cttcatccag aaggaggcgc ggccgctgtt tgacgtgaac accctgcaac acctgcctga
     8341 cgggttcgcg gtgatgaccg ggctgggcgt ggcgcggctg gcgttcagca gcccgctgcg
     8401 ggttgagcgc cgggaaattt cgctgaaaac cttcccggtg ctggcgaaaa cggacccgct
     8461 ggcggagtac ctgcctccgg ccgacggcgg cggaccaaaa gcggatgatg attttgcggg
     8521 gctttactga tgacactgga gcagtacaac gtcagccacg cgaagcggca ggcgcggaac
     8581 gcggagaaaa cacggctgac cctgcgctgg ctgcgggaag agctgtgttc cacggcggag
     8641 ctggttgcgc gacggctggg gattgcggcg gtacagccgg tttaccgctt cctggacagt
     8701 ctggtggcga aagggctgct ggtccgggcg aaatacccgg ttgacggccg tcaggtcagc
     8761 gtgtgggggc tgacgccgca cggggtggcg ttctcgttcg acgaggacga gccgctgacg
     8821 gacgttattc cgtttcagcc gtcaagggtg tcggcggcgc agctgccgca ccggctggcc
     8881 gtgcagtccc tgcgcctctc catggagggc cggggggcca ccggctggcg gtacctgcac
     8941 cgtatggccc tgaaagggat gaaagtgccg gacgcgctgg cggagctgga cggcagaacg
     9001 gtggcatttg aggtagagcg caccgtcaag agccgcaggc ggtatcagga agtggtgtcc
     9061 gggtatctgt tcaaccgccg ggcgaacggc atcgatgaaa tctggtacat ctgccctgac
     9121 cggccgacgc ttgtccgggt acagcgggcg attctggcgg tggatgaaat cgtgaatcca
     9181 cagaccggcg aggcccgcaa aacggtggag ctggaccggg agaggctgtt cgcgtgcttt
     9241 aaatttatga caacggagtg agggattatg gcgctgtaca tggtatttat tgaggacgtg
     9301 gaagacaaag acggcgagcg ctgcattatg ccaaccagcg agcatctgga agacatggtg
     9361 gtgctcgcct ggcagaccgg ggcgtatgtt ttctgttttg tcgaccgggc ccagcatctg
     9421 gcgatgatga aatccatcgg gatgtatgac gagcggctca acagcgacga aaaagccacg
     9481 tactttttca ccggtgaaaa tccgcaatgg gaacgggaca aacccacagg aatgaagctg
     9541 tgtgattacc tctatcgaaa ggtggagcgg ttcgccatcg agaacggtgt gcaggtggtt
     9601 gatgccggga agtgctcacc ggagcagatt aacgcgatga ttgaggtggt cagcgagcgg
     9661 cacggggaaa gcgcggtgaa cgagaagctg aaagcggagc tgatgcggga atataacagc
     9721 cgctatttta acgtgccggt gcctgaactg ccggaggaca aacccgcccg ccggtggtgg
     9781 ccgttcggca aaaaataacg ccagcaccgg catggccggt gctgttattc ttccccgagc
     9841 ttatcccgca tcacctgcca gagtgtttcc gcatcctcgt gaagccgttc gcacatgtcg
     9901 gccggggtat ccatgtccag ctcgttcagc ttttccagca acagcagcga ctgatcctta
     9961 atgaatttag ccatattgag ggcagttttt tcctgcttcg tcatgttctc cattcccttc
    10021 ggtaagttct cagctaaacc agccggacca gaagcgtttt ttcttctgtg tcagttctgt
    10081 tgtcaatctg tccacttcgg cctggagttt ccggcgctca tcatcgtgct ggcggcgttc
    10141 ttcttcccgg gatgttttat cttccagcat cagggtgaca gcctgccgga gatcggccag
    10201 ttccttttgc attgccagaa gctgttcctg tgggaaattt ttttgtgtat tttcacggtg
    10261 tgaaatgccg ggaatttgtt tctcagggat attcacattt ccgtatacac ggatcagttc
    10321 tgacacatcc acgacagggt tgtttttccc gtcacgtgac acggtaacct ttccctgttt
    10381 tacatgattg tatagcgttc ttctggtaat gcccgcggct tgtgctgcct gtgaaaggtt
    10441 gagcaatgtt ttcgccactg tatacccctg attttatcgg gtgtgaaagg tgtgtaattt
    10501 ctcacggtaa atgtatcgct gaattttacc cgtttttccg ttcaggatgt ggttttctga
    10561 cgcgctgcgc ttgtcaaacc ggcgacggcc acgcaatgaa ttgcgccccc gtcatcggtt
    10621 attagaggct gtctgccccc ggatacccgg attctttctg atgcctgacg gtgacgatca
    10681 caatctggtc catttcccgg tcgtggcggt agagcatcac atagccactg tcgccaaacc
    10741 cgatcaccag ttccttatat tccagcggca gaaacggcac cgggcggcca atgtctggca
    10801 atgttttcag ttgctggata gcccggacga tcacctcacc tccttttctg gctgccagcc
    10861 gatttttggt tttgagaaag tcctgaaggc gttgtaaatc gcgctgtgcc agcgcggaaa
    10921 tcgttacctg tggcatggcg gagcatcctg ctcgttctca gttccccagg tacttatcca
    10981 ggcttccgct tcttccgcag taaggtgcag acccgtttcc tgatagtgct gccatgcggc
    11041 ctgtccgtcc cgcaggtact ggctgcgctt ctcttcccgg tcgatgtatt cggtgattgc
    11101 ctccagcatt agcgcgtgcg ctgagcggtg ccggtcatcg gccagcgttt tcagccggtc
    11161 cttaagttct tcatcgagcc tgatggatgt tgctgatgac ataaaagccc ctttgtagtc
    11221 atatgtatta cacatgacta ctttaatccg tggcggcgct atttgccaga aatacggctt
    11281 ttgctgccca tttttcagct tcgcttccac taatcagggc tgctacaggc tcactcatca
    11341 tccaggacta ttgcagcctg cgggttaaag gacctgttac tggcggcaac catcatcatt
    11401 gagcttttgg gtggtgactg gtcgcggatc ctgtaagccg tcatttttca gactgaattc
    11461 aaaatttata acctgtcgca ttgccgggtg ccctgcggga tatagccagt gcctcattgc
    11521 cgtcagcgtt tcccgaaaaa aaaggtgaca gccggtaagc gacacgttgt ccactcgtcc
    11581 atcgtccaga atatcaaacg tggcggtcac ctgaccttcg atgcgttttg ctgcggcctg
    11641 taccgggtag gttggctgca gtgtggttac gggttttagt ggtatcgcat gtaccggagt
    11701 gaggaacatg gccgccagca ctgtcagagt aaaagctttc atggtctgaa atccagaggg
    11761 gcgtttttga atatttgcca ggtattttca tccggtgccg gcggaatttt ggcgtgggta
    11821 acggctgata ttgctgcttt acagagtttc ggatctcctc cttcagcaat ggcgctgttc
    11881 agagtgccat cacgttgtat ggatatccgc acggtgcaca tttttcccgc ataggcctct
    11941 ggttcaaaca tctgcatttc aacagcggtc ttgatggccg cagcgtagct actgatttta
    12001 gatgacttat ccagagtata aattttcggc ggctgggtgg tggaatgctt acaggccgtc
    12061 aggagtaagg ggctgcacaa tgccagcagg ataaagggta ttaaacgcat cgggttgatg
    12121 acctgtcagt aaaaaatgtt acatgtatat ttgtcactct ttacggccac gttcatttac
    12181 ataaacacgg cttatcgtat cgtttttaca ccaaacggcc cgccatgcag ttgcgtgcat
    12241 aggcatgcag cgggttacaa tttaccgggc gcgtttccgg cggttttccg ggtggtttgt
    12301 tgcctgtttt atcccgtagc cgccggaaac gccctcagac cgtctgagcg gtgcgggcaa
    12361 tgcgacgtta tggtaaatac cccttaccgg cggcgctgtg gctgccaggt gaaggtggtt
    12421 tccgtagcct cgtatttctc ccgacgcatt tcctgcgccc gcctggcttc acgttcgtcc
    12481 tgaatggcac gaagcaccct ttcccgcacc tgttgtttta ccgcctttgg cagcgttttg
    12541 ttccctttca ggcccatggc cagtgcctga gcgacaaagg cgtccgccag gcgcttttct
    12601 tcagcgggag tcagtttcag gtgcgtcata gtggcctccg ggcgtctcag gtttcccgaa
    12661 cagtttaacc gcaggtcctc tcctcatgcc agttagcttt cagatgtgtc tataccatct
    12721 gaaatgtaag tgtgatgaat gtcttaaata ataaaatttg ttgccatgag aaattttcgg
    12781 gaaaagacgc gatctgctta caggtggctc cgggcgcttt tttgtgcctg aagatgagaa
    12841 ctaatctcat atattgacac ctgaaaacgg gaggagtaag gtaataatta tactgtgtat
    12901 atgtacagtg tgtgccggga gaccggttag agatcaaggg gtgaaagtcc ccgaccattg
    12961 aaggaccagc aatccacaag gtccccgagt catgcgttgc ataccgcgag gtatggggcg
    13021 aagcgttgac aggggtgttg acaggccagc cattgagcca cgaaatgtat attaaattac
    13081 cgggtgccga cgttgtactg ttaacggaag gcaacatcat agggtgcgac actgcgagtg
    13141 ccacatggac ccggcggggt ctgagaccct ggcatgtcaa tacgatctct acgcgggaac
    13201 cgggagatct cccctctgac catctgccag tgtcggagat ggcccgcacc gggaagacga
    13261 ggagtcatag ccggtgatgt acggagagga gaagtcggac tcgctcatag tagcggcgaa
    13321 gcaggcgaac aacccgaaag gagcggagtc agtggagcga aggagcgggg ccaaggggaa
    13381 cgcggaacag ccacacatgc gccggacaca gagccgggaa agcatgtcac agaggctgtc
    13441 acgcgtgcgg gaagctgcga agcagcggaa gaaagaacgg tttacagcat tgttccacct
    13501 gctgacagtc gaagcactgg aagccgcatt cctctccctg agcaggaaag cggccgccgg
    13561 agtggatggc atcaggtgga tggactacgc cggaaacatg aagaacaaca taacagatct
    13621 gcaccggagg ctacatcagg gcagctacag ggcgcagccc ggcaggcgtc actacatccc
    13681 aaaagcggat ggaaaacaac gcccgctcgg catcgcctcg ctggaggaca agatcgtcca
    13741 gtatgcgctg gtgaaaatcc tgaacgcagt ctatgaaaac gactttatgg ggttctcata
    13801 cgggttcaga cccgggcgaa gccagcacga tgcactggac gcactggcca cagggctggt
    13861 acgcactaac gtaaactggg tactggatgc cgacatcagt cagttcttcg acagggtgag
    13921 ccacgaatgg ctgatcaggt tcacagagca tcggatcggc gaccggaggg taatcaggct
    13981 catacgtaag tggctcacag ccgggacgtc ggaggagggt caatggcgag caacggagga
    14041 aggcacccca cagggtgcgg tcatctcacc gctgctggca aacatatacc tccactacgt
    14101 cttcgatctg tgggcgcatc agtggcgacg tcgctatgcc acaggcaatg tggtaatggt
    14161 cagatacgcc gatgacatcg tcatcgggtt cgacaaacga tacgatgccc ggcgcttccg
    14221 tatagccatg cagcgcagac tgagggagtt cggactcacg gttcacccgg agaaaacccg
    14281 tctgatggag ttcggccgct tcgctgccga aaaccgtgcc atcaggggaa aaggcaaacc
    14341 agaaacgttc aacttcctcg ggttcacgca catcagcggg aaagatcgca acggcaggtt
    14401 catgctgata cgaaagaccc gccgggatcg gatgacggca actctgaaag ccatcaaaga
    14461 cggtctgcga aggcgctggc attactcaat ccccgaacag ggaaaatggc tcaggagagt
    14521 ggttcaggga tacctgaact atcactcggt accgggcaac ttccccacca tgcagaagtt
    14581 caggacacac gtaacaaacc tctggcgccg ggcgctcagg cgcaggagcc agaaggatga
    14641 tacgacctgg acgaaagcaa acaaactggc agccgcatgg ctaccaaggg ttcgggttct
    14701 tcatccatgg cctgtggagc ggttcaccgc cagacacccg aggcaggagc ccggtgcgta
    14761 aatcgcgcac gccgggatct gtgcgggggg tatccggtaa cgggtatccc taccgcgaca
    14821 tgttggcttt aatttattgt tttaaatgtc aaagaggaaa acggtatgag tggtggagac
    14881 ggtcgaggtc cgggtaattc aggtctggga cataatggtg gtcaggccag tgggaatgtg
    14941 aacggtacgt ctggtaaagg tggcccttca tcaggtggtg gtacggatcc aaacagcggg
    15001 ccgggctggg gtacgacgca tacgccgaat ggagatattc ataactataa tccgggggag
    15061 tttggtaacg gcgggagtaa acccggtggt aatggtggta acagcggcaa tcatagcggt
    15121 agctctggtg gcggacagtc ttcggccact gcgatggcct tcggtctgcc tgccctggct
    15181 actccggggg ctgaaggact ggctttatca gtttccggcg atgcgttgtc ggccgccgtt
    15241 gctgatgtgc tggctgccct gaaggggccg tttaagtttg gtctgtgggg gattgcgatc
    15301 tacggtgtgc tgccttctga gattgcaaaa gatgatccga aaatgatgtc aaaaattatg
    15361 acgtcattac cggccgatgc ggtgacggag actccggcaa gtactttacc actggaccag
    15421 gcgacggttc gtgtcagaca acgggttgtg gatgtggtga aggatgagcg gcagcatatt
    15481 gcggttgtcg caggtcggcc aatgagtgtc cctgtggtgg atgcgaaacc gacaaaacgt
    15541 ccgggggtat tcagtgtgtc gattccgggt ctcccgtctc tgcaggtgag cgtaccgaaa
    15601 ggtgttccga cagcgaaagc cccgccaaaa ggcattgttg ctgaaaaagg tgattcacgt
    15661 ccggctggtt ttacagccgg tggtaactcc cgtgaggccg ttattcgttt cccgaaagag
    15721 accggacaga agccggttta tgtgtcggtg acagatgttc ttaccccggc acaggtaaaa
    15781 cagcgtcagg aggaagaaaa gcgtcgccag caggcatggg acgccgctca tccggaagag
    15841 gggctgaaaa gagactatga taaagcgaaa gctgagctgg atgccgaaga taaaaatatt
    15901 gcgaccttaa acagccgcat tgcatcgaca gagaaggcgc tccccggtgc aagggctgct
    15961 gttcaggaag ccgataaaaa ggtaaaagag gcagaggcaa ataaagatga ttttgtgact
    16021 tataacccgc ctcatgaata tggctccggg tggcaggatc aggttcgcta tcttgataag
    16081 gatattcaga atcagaatga gaaattaaaa gcggctcagg catctttaaa cgcaatgaat
    16141 gaatccttat ccagagataa ggctgcactt accggggcga tggagagccg gaaacaaaag
    16201 gagaaaaaag cgaaggatgc agaaaataag ttaaatgagg aaaagaacaa gcctcgcaag
    16261 gggactaaag actacggcca tgattatcat ccagtaccta aaacagaaga cataaaggga
    16321 cttggagagt taaagcgagg tgatcctaaa acacctaaac aaggtggtgg tggtaagcgg
    16381 gcccgatggt atggcgataa aaaacgtaaa atttatgaat gggattccca gcacggtgag
    16441 cttgaagggt atcgtgccag tgatggcgaa cacctaggcg catttgatcc caaaacgggt
    16501 aagcaggtta aagggccaga tccaaaacgg aacattaaaa aatatctttg agaggtaaat
    16561 atggggctta aattacgttt gacatggttt gataagaaaa ctgaagagtt taaaggggaa
    16621 gagtattcta aagactttgg tgacgatggt tctgtcattg aaagcttggg aatgccttta
    16681 aaggataata ttaataatgg tgagtttgat ttgaagaaag aatgggttcc tttactacag
    16741 ccatttttta aaaatcaaat aaaacctgat gtggataatt gttatatagc ttttgattat
    16801 cgggacggta actggtaaca aaaaattatc aaggatgatt tgaaatactg acttccggtg
    16861 ttcagggatg aatgccggag tctttaaata cagggaaagt atatgaaaaa ggtaaagact
    16921 atttttcttt ttatattgat tgttgctggc tttcttctgg ccgcatgtca ggcaaattat
    16981 atccgggatg ttcagggcgg aacggtggca ccatcgtcct cctctgaact gacggggatc
    17041 gcggttcagt agaaaagatc aaaggatctt cttgagatcc tttttttctg cgcgtaatct
    17101 tttgccctgt aaacgaaaaa accacctggg gaggtggttt gatcgaaggt taagtcagtt
    17161 ggggaactgc ttaaccgtgg taactggctt tcgcagagca cagcaaccaa atctgtcctt
    17221 ccagtgtagc cggactttgg cgcacacttc aagagcaacc gcgtgtttag ctaaacaaat
    17281 cctctgcgaa ctcccagtta ccaatggctg ctgccagtgg cgttttgcgt gctttcccgg
    17341 gttggactca agtgaacagt taccggataa ggcgcagcag tcgggctgaa cggggagttc
    17401 ttgcttacag cccagcttgg agcgaacgac ctacaccgag ccgagatacc agtgtgtgag
    17461 ctatgagaaa gcgccacact tcccgcaagg gagaacggcg gacaggtatc cggtaaacgg
    17521 cagggtcgga acaggagagc gcaagaggga gcgacctacc ggaaacggtg gggatcttta
    17581 agtcctgtcg ggtttcgccc gtactgtcag attcatggtt gagcctcacg gctcccacag
    17641 atgcaccgaa aaagcgtctg tttatgtgaa ctctggcagg agggcggagc ctatggaaaa
    17701 acgccaccgg cgcggccctg ccgttttgcc tcacatgtta gtcccctgct tatccacgga
    17761 atctgtgggt aactttgtat gtgtccgcag cgcccgccgc agtctcacgc ccggagcgta
    17821 gcgaccgagt gagcgaggag gcgcaatttc cccggcacct gcaagacggt caccggacgc
    17881 gctgatgtgg gatattgtcc cctgattaag tctttctatt ccctgacgat caattatcag
    17941 gataggtgaa ccatgtcggt ttttcgctga acattttacg ttaacctatc tctgttgctt
    18001 ttttctcctt gcggagaaat gcaagtcatc cccgctgggg cgtggctgac ttcaggggaa
    18061 aagaccttgc ttacgctggc tggacgccac cgacgcacgg tcttttcccc tctttctggc
    18121 tctgtccggc tggacgccgg ccacgccaga aattcacccg gcccccgtca ggctcacgcc
    18181 tgaccaccca caaaaatcca cggtgctgga cgcacctgac gaagcagcaa agctgctcct
    18241 gattttgcgg gtggtcagcc gctcgctatg gcgaactctg acgggggccg gaacaccgga
    18301 aaagaccgca ctggggtgcc gccttttcct ctcacacgct ggggcgtgct cgttgttcct
    18361 ccggggctgc gccttttccg catggggcgg aaagaggctg gcctccgcgg tgaaagctga
    18421 acgcaatcac cacggacgtg accgccgccg ccatgccttg gggcatgtcc gcggcttgtg
    18481 cagcgggggc tgcgcatcac gccggtaaac ccgtcgtctg aaggagagag attgcatgtt
    18541 taatacggat tcgcttgcct ggcagtggca tatcccggag ctggcccggc agatttaccc
    18601 gtgggtcagc tggctgtacc gggagtatta cagtctggcc ggtttttttt ctggttatcg
    18661 gcctgttttt cggtctggct gaactctggg ccggccgaat gcgttttgtg gggctgagcc
    18721 ataaggcgcg gcgggagtat gccgatcgct ataagcgcga taataaccgg actgtgccat
    18781 tttcggtgct ggcctcgctg gattcacccg ggcggatggt cagggcacgg cgacatgtct
    18841 ggaactacgc gtactggctg accggcgctg ccggtctggc ccttctgggg gggctggttg
    18901 tcgccgtgtt tatcgagagc tggggagaaa ccgtcctgcg cccggacctc tatgcgaacg
    18961 cagattatta cctgctgcag ccggctaacc tgttcgggat agcctggtgt gccggagggc
    19021 ttgtcgccgg cgtccttctg gcgcggctgc tggcgttcct gctgcttgat ggtcattttg
    19081 cggccgctga cgaggcggtg aacgcgaaac tgaatcagga gagccggcgc agcagccagc
    19141 ggaccggaga aatgacagac gtccgccacc tgcatttcgg ggagccggta ccggttaacg
    19201 cgctggccga tttttccacg gagcaggccc ggaaacagca ggcggtgttt ctgggtaagg
    19261 atgagcaggg ccagccggtg ctggtccctc gtgatacctg gcgcaagacc aatattcaga
    19321 tcctcggcct gcccgggagc ggcaagagcg cgatggccac caacgcgctc attcgctgcg
    19381 tacgcgattt cggggacgct gtggtgtact tcgaccccaa aggggacgcg tgggcgccgc
    19441 acgtcttccg ggcgcactgc ccggacttca ccctgctgga tctgcggccg gggaaaccgg
    19501 cgcagctgaa tctgttccgc gatctcgacc agtacgccct gaagaatctg ctggttgccg
    19561 ggtttaacct gagtgagacc ggcgacgtgg cggaccacta ccgcatcagc gagcagaaag
    19621 cggcgaagct gattgcggag cagttcccgc agggggcaaa cattcagcag gtgctggcgg
    19681 cggcgtacgc gttgccggag gccctgaaaa aggacgtgaa ggggctgatc accaagctgg
    19741 agaacgtggc cgacctgagc gtcctgcaga cggacagcgg tatcgatgtg gcggggataa
    19801 tcaacggcgg cggctgcctg tacgtcatcg gctcgatgga cgatgaggcg gtgatccggg
    19861 tgcagaagat gctgtttgcc cgctgcgcgc aaatcatcat tgcgcgggat gagttccgga
    19921 ggtggccgca cgcgagcatc atgctcgatg agattaaata tctgctgtcg aagtacgtgc
    19981 tgaacgcgct ggggacgctg cgcagccggg actgcaacct gctgctcgcg caccagtcgc
    20041 tgggcgactt cggtcagtgc gggcaggatc tgcccgctga ttttgtgaaa accacggtac
    20101 tggataacac gccgatccgc tggttctatc gcgcggccag ccaggagtcc gcgcagtggg
    20161 cggcgggcca gaccggggag atccgggtgg acgtggagcg ccgccgggcc agccgggagg
    20221 cggggaacgt ggagcacatc agcggcgaca gcttcatcca gaaggaggcg cggccgctgt
    20281 ttgacgtgaa caccctgcaa cacctgcctg acgggttcgc ggtgatgacc gggctgggcg
    20341 tggcgcggct ggcgttcagc agcccgctgc gggttgagcg ccgggaaatt tcgctgaaaa
    20401 ccttcccggt gctggcgaaa acggacccgc tggcggagta cctgcctccg gccgacggcg
    20461 gcggaccaaa agcggatgat gattttgcgg ggctttactg atgacactgg agcagtacaa
    20521 cgtcagccac gcgaagcggc aggcgcggaa cgcggagaaa acacggctga ccctgcgctg
    20581 gctgcgggaa gagctgtgtt ccacggcgga gctggttgcg cgacggctgg ggattgcggc
    20641 ggtacagccg gtttaccgct tcctggacag tctggtggcg aaagggctgc tggtccgggc
    20701 gaaatacccg gttgacggcc gtcaggtcag cgtgtggggg ctgacgccgc acggggtggc
    20761 gttctcgttc gacgaggacg agccgctgac ggacgttatt ccgtttcagc cgtcaagggt
    20821 gtcggcggcg cagctgccgc accggctggc cgtgcagtcc ctgcgcctct ccatggaggg
    20881 ccggggggcc accggctggc ggtacctgca ccgtatggcc ctgaaaggga tgaaagtgcc
    20941 ggacgcgctg gcggagctgg acggcagaac ggtggcattt gaggtagagc gcaccgtcaa
    21001 gagccgcagg cggtatcagg aagtggtgtc cgggtatctg ttcaaccgcc gggcgaacgg
    21061 catcgatgaa atctggtaca tctgccctga ccggccgacg cttgtccggg tacagcgggc
    21121 gattctggcg gtggatgaaa tcgtgaatcc acagaccggc gaggcccgca aaacggtgga
    21181 gctggaccgg gagaggctgt tcgcgtgctt taaatttatg acaacggagt gagggattat
    21241 ggcgctgtac atggtattta ttgaggacgt ggaagacaaa gacggcgagc gctgcattat
    21301 gccaaccagc gagcatctgg aagacatggt ggtgctcgcc tggcagaccg gggcgtatgt
    21361 tttctgtttt gtcgaccggg cccagcatct ggcgatgatg aaatccatcg ggatgtatga
    21421 cgagcggctc aacagcgacg aaaaagccac gtactttttc accggtgaaa atccgcaatg
    21481 ggaacgggac aaacccacag gaatgaagct gtgtgattac ctctatcgaa aggtggagcg
    21541 gttcgccatc gagaacggtg tgcaggtggt tgatgccggg aagtgctcac cggagcagat
    21601 taacgcgatg attgaggtgg tcagcgagcg gcacggggaa agcgcggtga acgagaagct
    21661 gaaagcggag ctgatgcggg aatataacag ccgctatttt aacgtgccgg tgcctgaact
    21721 gccggaggac aaacccgccc gccggtggtg gccgttcggc aaaaaataac gccagcaccg
    21781 gcatggccgg tgctgttatt cttccccgag cttatcccgc atcacctgcc agagtgtttc
    21841 cgcatcctcg tgaagccgtt cgcacatgtc ggccggggta tccatgtcca gctcgttcag
    21901 cttttccagc aacagcagcg actgatcctt aatgaattta gccatattga gggcagtttt
    21961 ttcctgcttc gtcatgttct ccattccctt cggtaagttc tcagctaaac cagccggacc
    22021 agaagcgttt tttcttctgt gtcagttctg ttgtcaatct gtccacttcg gcctggagtt
    22081 tccggcgctc atcatcgtgc tggcggcgtt cttcttcccg ggatgtttta tcttccagca
    22141 tcagggtgac agcctgccgg agatcggcca gttccttttg cattgccaga agctgttcct
    22201 gtgggaaatt tttttgtgta ttttcacggt gtgaaatgcc gggaatttgt ttctcaggga
    22261 tattcacatt tccgtataca cggatcagtt ctgacacatc cacgacaggg ttgtttttcc
    22321 cgtcacgtga cacggtaacc tttccctgtt ttacatgatt gtatagcgtt cttctggtaa
    22381 tgcccgcggc ttgtgctgcc tgtgaaaggt tgagcaatgt tttcgccact gtatacccct
    22441 gattttatcg ggtgtgaaag gtgtgtaatt tctcacggta aatgtatcgc tgaattttac
    22501 ccgtttttcc gttcaggatg tggttttctg acgcgctgcg cttgtcaaac cggcgacggc
    22561 cacgcaatga attgcgcccc cgtcatcggt tattagaggc tgtctgcccc cggatacccg
    22621 gattctttct gatgcctgac ggtgacgatc acaatctggt ccatttcccg gtcgtggcgg
    22681 tagagcatca catagccact gtcgccaaac ccgatcacca gttccttata ttccagcggc
    22741 agaaacggca ccgggcggcc aatgtctggc aatgttttca gttgctggat agcccggacg
    22801 atcacctcac ctccttttct ggctgccagc cgatttttgg ttttgagaaa gtcctgaagg
    22861 cgttgtaaat cgcgctgtgc cagcgcggaa atcgttacct gtggcatggc ggagcatcct
    22921 gctcgttctc agttccccag gtacttatcc aggcttccgc ttcttccgca gtaaggtgca
    22981 gacccgtttc ctgatagtgc tgccatgcgg cctgtccgtc ccgcaggtac tggctgcgct
    23041 tctcttcccg gtcgatgtat tcggtgattg cctccagcat tagcgcgtgc gctgagcggt
    23101 gccggtcatc ggccagcgtt ttcagccggt ccttaagttc ttcatcgagc ctgatggatg
    23161 ttgctgatga cataaaagcc cctttgtagt catatgtatt acacatgact actttaatcc
    23221 gtggcggcgc tatttgccag aaatacggct tttgctgccc atttttcagc ttcgcttcca
    23281 ctaatcaggg ctgctacagg ctcactcatc atccaggact attgcagcct gcgggttaaa
    23341 ggacctgtta ctggcggcaa ccatcatcat tgagcttttg ggtggtgact ggtcgcggat
    23401 cctgtaagcc gtcatttttc agactgaatt caaaatttat aacctgtcgc attgccgggt
    23461 gccctgcggg atatagccag tgcctcattg ccgtcagcgt ttcccgaaaa aaaaggtgac
    23521 agccggtaag cgacacgttg tccactcgtc catcgtccag aatatcaaac gtggcggtca
    23581 cctgaccttc gatgcgtttt gctgcggcct gtaccgggta ggttggctgc agtgtggtta
    23641 cgggttttag tggtatcgca tgtaccggag tgaggaacat ggccgccagc actgtcagag
    23701 taaaagcttt catggtctga aatccagagg ggcgtttttg aatatttgcc aggtattttc
    23761 atccggtgcc ggcggaattt tggcgtgggt aacggctgat attgctgctt tacagagttt
    23821 cggatctcct ccttcagcaa tggcgctgtt cagagtgcca tcacgttgta tggatatccg
    23881 cacggtgcac atttttcccg cataggcctc tggttcaaac atctgcattt caacagcggt
    23941 c
//
