LOCUS       NZ_CP152122            27079 bp    DNA     circular CON 18-MAY-2024
DEFINITION  Staphylococcus aureus strain BSN62-2 plasmid pUSA04, complete
            sequence.
ACCESSION   NZ_CP152122
VERSION     NZ_CP152122.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38351595
            Assembly: GCF_034105255.2
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27079)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN62-2 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27079)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
REFERENCE   3  (bases 1 to 27079)
  AUTHORS   Berti,A.D. and Monk,J.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-NOV-2023) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN62-2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly :: CP043386, CP014443, CP014442, CP003981
            Genome Coverage                   :: 119.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_034105255.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 00:07:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,999
            CDSs (total)                      :: 2,917
            Genes (coding)                    :: 2,829
            CDSs (with protein)               :: 2,829
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 48 of 88
            Pseudo Genes (incomplete)         :: 45 of 88
            Pseudo Genes (internal stop)      :: 15 of 88
            Pseudo Genes (multiple problems)  :: 19 of 88
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP152122.1.
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University, Detroit MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27079
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN62-2"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pUSA04"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2019-05-19"
                     /collected_by="Andrew D. Berti"
                     /genotype="ST8-MRSA-IVa CC8"
     gene            join(26870..27079,1..465)
                     /locus_tag="SL323_RS14835"
                     /old_locus_tag="SL323_14840"
     CDS             join(26870..27079,1..465)
                     /locus_tag="SL323_RS14835"
                     /old_locus_tag="SL323_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <606..1241
                     /locus_tag="SL323_RS14840"
                     /old_locus_tag="SL323_14845"
                     /pseudo=""
     CDS             <606..1241
                     /locus_tag="SL323_RS14840"
                     /old_locus_tag="SL323_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            1238..1768
                     /gene="sat4"
                     /locus_tag="SL323_RS14845"
                     /old_locus_tag="SL323_14850"
     ARG             1239..1765
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            1861..2655
                     /gene="aph(3')-IIIa"
                     /locus_tag="SL323_RS14850"
                     /old_locus_tag="SL323_14855"
     ARG             1862..2652
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3137..>3612
                     /locus_tag="SL323_RS14855"
                     /old_locus_tag="SL323_14860"
                     /pseudo=""
     CDS             3137..>3612
                     /locus_tag="SL323_RS14855"
                     /old_locus_tag="SL323_14860"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /name="WYL domain-containing protein"
     gene            complement(3671..4345)
                     /locus_tag="SL323_RS14860"
                     /old_locus_tag="SL323_14865"
     CDS             complement(3671..4345)
                     /locus_tag="SL323_RS14860"
                     /old_locus_tag="SL323_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            4607..4792
                     /locus_tag="SL323_RS14865"
                     /old_locus_tag="SL323_14870"
     CDS             4607..4792
                     /locus_tag="SL323_RS14865"
                     /old_locus_tag="SL323_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(5015..5593)
                     /locus_tag="SL323_RS14870"
                     /old_locus_tag="SL323_14875"
     CDS             complement(5015..5593)
                     /locus_tag="SL323_RS14870"
                     /old_locus_tag="SL323_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(5857..6237)
                     /gene="blaI"
                     /locus_tag="SL323_RS14875"
                     /old_locus_tag="SL323_14880"
     ARG             complement(5861..6237)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(6227..7984)
                     /gene="blaR1"
                     /locus_tag="SL323_RS14880"
                     /old_locus_tag="SL323_14885"
     ARG             complement(6231..7984)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            8091..8936
                     /gene="blaZ"
                     /locus_tag="SL323_RS14885"
                     /old_locus_tag="SL323_14890"
     ARG             8092..8933
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9462..9881)
                     /locus_tag="SL323_RS14890"
                     /old_locus_tag="SL323_14895"
     CDS             complement(9462..9881)
                     /locus_tag="SL323_RS14890"
                     /old_locus_tag="SL323_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            10005..10976
                     /locus_tag="SL323_RS14895"
                     /old_locus_tag="SL323_14900"
     CDS             10005..10976
                     /locus_tag="SL323_RS14895"
                     /old_locus_tag="SL323_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(11148..11240)
                     /locus_tag="SL323_RS14900"
                     /old_locus_tag="SL323_14905"
     CDS             complement(11148..11240)
                     /locus_tag="SL323_RS14900"
                     /old_locus_tag="SL323_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(11397..11744)
                     /locus_tag="SL323_RS14905"
                     /old_locus_tag="SL323_14910"
     CDS             complement(11397..11744)
                     /locus_tag="SL323_RS14905"
                     /old_locus_tag="SL323_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(11763..12380)
                     /gene="cadD"
                     /locus_tag="SL323_RS14910"
                     /old_locus_tag="SL323_14915"
     ARG             complement(11767..12380)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13496..13690)
                     /locus_tag="SL323_RS14915"
                     /old_locus_tag="SL323_14920"
     CDS             complement(13496..13690)
                     /locus_tag="SL323_RS14915"
                     /old_locus_tag="SL323_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            13800..14492
                     /locus_tag="SL323_RS14920"
                     /old_locus_tag="SL323_14925"
     CDS             13800..14492
                     /locus_tag="SL323_RS14920"
                     /old_locus_tag="SL323_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(14660..14809)
                     /locus_tag="SL323_RS14925"
                     /old_locus_tag="SL323_14930"
     CDS             complement(14660..14809)
                     /locus_tag="SL323_RS14925"
                     /old_locus_tag="SL323_14930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(15356..>15645)
                     /locus_tag="SL323_RS14930"
                     /old_locus_tag="SL323_14935"
                     /pseudo=""
     CDS             complement(15356..>15645)
                     /locus_tag="SL323_RS14930"
                     /old_locus_tag="SL323_14935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(15665..16648)
                     /locus_tag="SL323_RS14935"
                     /old_locus_tag="SL323_14940"
     CDS             complement(15665..16648)
                     /locus_tag="SL323_RS14935"
                     /old_locus_tag="SL323_14940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            17074..17817
                     /locus_tag="SL323_RS14940"
                     /old_locus_tag="SL323_14945"
     CDS             17074..17817
                     /locus_tag="SL323_RS14940"
                     /old_locus_tag="SL323_14945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(18044..18229)
                     /locus_tag="SL323_RS14945"
                     /old_locus_tag="SL323_14950"
     CDS             complement(18044..18229)
                     /locus_tag="SL323_RS14945"
                     /old_locus_tag="SL323_14950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(18234..18572)
                     /locus_tag="SL323_RS14950"
                     /old_locus_tag="SL323_14955"
     CDS             complement(18234..18572)
                     /locus_tag="SL323_RS14950"
                     /old_locus_tag="SL323_14955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(18829..19437)
                     /locus_tag="SL323_RS14955"
                     /old_locus_tag="SL323_14960"
     CDS             complement(18829..19437)
                     /locus_tag="SL323_RS14955"
                     /old_locus_tag="SL323_14960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(19923..20822)
                     /locus_tag="SL323_RS14960"
                     /old_locus_tag="SL323_14965"
     CDS             complement(19923..20822)
                     /locus_tag="SL323_RS14960"
                     /old_locus_tag="SL323_14965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(20921..22387)
                     /gene="msr(A)"
                     /locus_tag="SL323_RS14965"
                     /old_locus_tag="SL323_14970"
     ARG             complement(20925..22387)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22861..23535
                     /locus_tag="SL323_RS14970"
                     /old_locus_tag="SL323_14975"
     CDS             22861..23535
                     /locus_tag="SL323_RS14970"
                     /old_locus_tag="SL323_14975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <23593..23970
                     /locus_tag="SL323_RS14975"
                     /old_locus_tag="SL323_14980"
                     /pseudo=""
     CDS             <23593..23970
                     /locus_tag="SL323_RS14975"
                     /old_locus_tag="SL323_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            23967..24848
                     /locus_tag="SL323_RS14980"
                     /old_locus_tag="SL323_14985"
                     /pseudo=""
     CDS             23967..24848
                     /locus_tag="SL323_RS14980"
                     /old_locus_tag="SL323_14985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            24964..25893
                     /locus_tag="SL323_RS14985"
                     /old_locus_tag="SL323_14990"
     CDS             24964..25893
                     /locus_tag="SL323_RS14985"
                     /old_locus_tag="SL323_14990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            25886..26623
                     /locus_tag="SL323_RS14990"
                     /old_locus_tag="SL323_14995"
     CDS             25886..26623
                     /locus_tag="SL323_RS14990"
                     /old_locus_tag="SL323_14995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            26637..>26813
                     /locus_tag="SL323_RS14995"
                     /old_locus_tag="SL323_15000"
                     /pseudo=""
     CDS             26637..>26813
                     /locus_tag="SL323_RS14995"
                     /old_locus_tag="SL323_15000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     ARG             complement(19927..20822)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(20922..22387)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(19924..20822)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             1251..1768
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             643..944
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             8092..8936
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(15153..15300)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(15359..15534)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(15666..16648)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17075..17817
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tacaaatggc gtattgatga gacgtatatc aaaataaaag gaaaatggag ctatttatat
       61 cgtgccattg atacagaggg acatacatta gatatttggt tgcgtaagca acgagataat
      121 cattcagcat atgcgtttat caaacgtctc attaaacaat ttggtaaacc tcaaaaggta
      181 attacagatc aggcaccttc aacgaaggta gcaatggtta aagtaattaa agcttttaaa
      241 cttaaacctg actgccattg tacatcgaaa tatctgaata acctcattga gcaagatcac
      301 cgtcatatta aagtaagaaa gacaaggtat caaagtatca atacagcaaa gaatacttta
      361 aaaggtattg agtgtattta cgctctatat aaaaagaacc gcaggtctct tcagatctac
      421 ggattttcgc catgccacga aattagcatc atgctagcaa gttaaacgaa cactgacatg
      481 atatattagt gattagctat attttttact ttgcaacaga accatcattt ttattaaaat
      541 actcttttgt aaaatctttc tgctcttcaa tgtatttaat ttctttacct ctaaatctat
      601 tatagctatt tgatgattac aataaaattg atcttacctt attgcccttg gaagagttag
      661 ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat tgtagaatta
      721 aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc gcaagggagt
      781 atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa ggattgtgcc
      841 gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat gagctgctga
      901 gaatgatatc atggaaggtc ggcatcgaaa caggctttaa atgaagtgta ggcaagaact
      961 ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg tccacctacc
     1021 ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa ttgttcaggg
     1081 cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat gataggaata
     1141 taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc tgcctggata
     1201 gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa tgaaagcagg
     1261 gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta agattatacc
     1321 gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc catatttaaa
     1381 aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg aatatattga
     1441 caatactgat aagataatat atctttacta ccaagacgat aaatgcgtcg gaaaagttaa
     1501 actgcgaaaa aattggaacc ggtacgctta tatagaagat atcgccgtat gtaaggattt
     1561 cagggggcaa ggcataggca gcgcgcttat caatatatct atagaatggg caaagcataa
     1621 aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt gtaaattcta
     1681 tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca actttgaaaa
     1741 agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg agttcgtctt
     1801 gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag gaaataataa
     1861 atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata ccgctgcgta
     1921 aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga aaatgaaaac
     1981 ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt ggaacgggaa
     2041 aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct gcactttgaa
     2101 cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct ttgctcggaa
     2161 gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga gtgcatcagg
     2221 ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga cagccgctta
     2281 gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga aaactgggaa
     2341 gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac ggaaaagccc
     2401 gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt tgtgaaagat
     2461 ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa gtggtatgac
     2521 attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta tgtcgagcta
     2581 ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta tattttactg
     2641 gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac aagcttttta
     2701 gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt tttatatctt
     2761 ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt ggtgaagagg
     2821 tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc agctagctta
     2881 agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat ttgaacagga
     2941 ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaataattc ctgccaaaga
     3001 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     3061 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     3121 cctacttctg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     3181 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     3241 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     3301 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     3361 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     3421 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     3481 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     3541 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     3601 aaacaaatgc tggttctgtt gcaaagtaaa aaaatatagc taaccactaa tttatcatgt
     3661 cagtgttcgt ttaacttgct agcatgatgc taatttcgtg gcatggcgaa aatccgtaga
     3721 tctgaagaga cctgcggttc tttttatata gagcgtaaat acactcaata ccttttaaag
     3781 tattctttgc tgtattgata ctttgatacc ttgtctttct tactttaata tgacggtgat
     3841 cttgctcaat gaggttattc agatatttcg atgtacaatg gcagtcaggt ttaagtttaa
     3901 aagctttaat tactttaacc attgctacct tcgttgaagg tgcctgatct gtaattacct
     3961 tttgaggttt accaaattgt ttaatgagac gtttgataaa cgcatatgct gaatgattat
     4021 ctcgttgctt acgcaaccaa atatctaatg tatgtccctc tgcatcaatg gcacgatata
     4081 aatagctcca ttttcctttt attttgatgt acgtctcatc aatacgccat ttgtaataag
     4141 cttttttatg ctttttcttc caaatttgat ataaaattgg ggcatattct tgaacccaac
     4201 ggtagaccgt tgaatgatga acgtttacac cacgttccct taatatttca gatatatcac
     4261 gataactcaa tgcatatctt agatagtagc caacagctac agtgataaca tccttgttaa
     4321 attgtttata tctgaaatag ttcatacaga agactccttt ttgttaaaat tatactataa
     4381 attcaacttt gcaacagaac ctcatttact atatgggcat ctctttcatt attaatacaa
     4441 agctttgtat ctccgatatt aggcaaaggt gtaaacgaat taggtgatac tataggattc
     4501 aacattatat taatcgtttc tttaataatg attatcttct tattttttat aaatcgtagt
     4561 aaaaatatct cctatgatta tataaaagtt caaagaggtg aagccaatga ataaattaga
     4621 aaaatggtct ttggtattta ttatttttac atttctctct tcattagcac ttttatattt
     4681 caaatataat tttagttcgg ttatgccagt cctaagtctt tctattttaa ctatactaat
     4741 attgttgacg agtattatta ctgtagtttc agttaatgat gaagatactt aaaacgttca
     4801 ttagtgaaac aggtattata ttaaaaaagc gtacgaattt gtacgctttt ttcttgtgtt
     4861 attattaaaa tctcataaca ggaaaatatt atgagatttt agacgctgtc agaacgtctc
     4921 ttttacatcg agtgacattg aatcaaagtc tttgtatgtt aatgatatat aaaattattt
     4981 agtagattca ttatagtaag ctagattagt tgctctactt gtttttattc tcttttgcct
     5041 ctaatttatt gagataacga taaatagttg tacgtgaaac ttgccactgc tctgcaattg
     5101 ttttaattgg cgtaccatta tcataaagtg tcttaagtaa gtttaaatct tgtttattta
     5161 atttttcagg tctacctcca tatcggcctc tagcacgtgc tgcaattcga ccggctgatg
     5221 atcgctctaa aattaaatta cgttcaaact ctgcaaatgc tgcgaataaa tgaaataata
     5281 attgtcctgt agaacttgat ttatccatcg ttatattttc ttctaaacta tgaaaactca
     5341 cacctcgttc gttaagttca ttaactaacg tgattaaatc ctccatgttc cgtcctagtc
     5401 tatctaatct ccaaacaaca atcgtatctc ctgacctcgc aaattcaatt gctttatcta
     5461 aaccaggtcg cttacttttt gaaccactca tatggtcatt aaatatcttt tcacaaccat
     5521 atgtatttaa tcgatcctcc tgtaaattca aattttgtaa tccagttgaa actcttgcat
     5581 aacctatttt caaaatacag acctcctata tacaccttta gtgtaccata acttgattac
     5641 gaggtctttt gtgaacatag attttttgtt gggtttttga acacataatt ctatgtaata
     5701 cttacttatt tagacaaaaa acaagagtgt acagaaaatg gttattttct ggacactctc
     5761 atctttaata atatatttta aatgtcatta acaaaactaa tttaataaga gtcaagtatg
     5821 gtttacatat gtattatgtt tgaaacatac ctctaattac tttttactaa tatcatttaa
     5881 aatgtctcgc aattcttcaa tttctttgtt atttaattct tcatttttcg caaaattcag
     5941 cactaaactt ttcatatccc ctccatacag tttattaaga aaggttttag cagttttcat
     6001 tttaatatcg tcttctttaa tatttgatga gtaaaaataa atattttctg atttgtatcg
     6061 ttttataatc tcttttttat atagtcttgt gattaatgtt ctaatcgttt tatcactaac
     6121 ttctttatat ttttgaattt caactacaat ttcattagct gatactgatt ttttatccca
     6181 tattatattc ataacatccc attcagccat agatatttca acttgcttat tggtcattta
     6241 aaacacccat tccttttaat attttttcac ttattaattc agcatttttc ccagacgggt
     6301 ttccatctga taaatgtgta gcaaaataat acttatcatg atttgtaatt acgtaaccta
     6361 caaaccaccc attattatac ttcccgttta ctatacctgt acctgttttc ccatacagtt
     6421 catacttttc atttttctta atcaataatg aagaagataa ttgattcttt gcttttttac
     6481 taaaatggtt attttgttcc atcatatttt taaaaactat tacttgttca agattagata
     6541 ttttcaaact atcttccatc caatagcttt tataacttcc caaattttca ttaccataat
     6601 ttaattgctt gagttgagcc gcagtatagt tctttggtat ttgattacta atacgttcga
     6661 agtaccaatt aactgaattt tgcattgctg tatttaaatc ttgttcctta ttccaagact
     6721 cgaaaagata atgtttatga ttccatgaca tacgtgaatt tttatcactt ataatatgac
     6781 ggtcaagtcc aaacagtgct aaataaattt tgtaagttga atcaggagaa tatctttttc
     6841 tactttcttt ttcattataa atatagtatt tgtctttctt catgctgtac ataacgaaag
     6901 atccactatt tgaaccaaaa tttttacttt catctaaaat ttggtaatcg ctttgtaagg
     6961 gctttttata attataatca gttaaggatt gccccattaa aaactggctt tgaattatca
     7021 tgataaaaaa agtaaaaata caaataaaaa ttagaattaa ttttgactgc tttttcagat
     7081 cggcttcttt tatattaatt aatctacttt tgagtaatga ttttttacca ttaaatgaat
     7141 ggcttaatat atttttgttg gaaaatgggg tttttaatac ggagtccata atagattccg
     7201 cataagtttt aaattcattt ttgttaatat tattaaggac aaatctatcg gcttctactt
     7261 cattgtcatg aattatcttt ctttttacaa tatgtactaa tggattgtaa ctcataataa
     7321 tagagaagat attaaagata attaaatgta aagtatctct atttttagca tgagcatatt
     7381 catgcagtat tatatatttt agtcttttat caattacact tttaaaatat gaactaggaa
     7441 tcaaaataat atatttccca taccaaaaag ttattggaga ttgaatagcc tctgcttttc
     7501 gaatcacaat atttttttta tattgatggt tgaaaagtat cgtatctatt ttattttttt
     7561 cattttcgtt tagataaagt gactgtttct ttaaatattt aagatataat aaggctttca
     7621 aaaatttaaa acttaaaata ataactaaaa ctatccaaat aactgtgcag atattatcaa
     7681 ttgaatccca attaaactta tggatatctg ttgtgaactc ttgaataggt ttggtggtat
     7741 ttatgttatg gttcaaatcg tgtgacttac tttcaactgt gggcgcttga ttattcacat
     7801 tattaaattt tataaaagag aatttaattg ggataaaagg aattaatcca gcaagcatag
     7861 ttagatacca aactttataa tttaaactat aattaaaata gcgttttaat atgtacctaa
     7921 aaaatactaa caatagaaat ataaaacaaa agcttactac gctcattatt agtaatttag
     7981 ccattttgac accttctttc aaatatttat aataaacaat tgacatcaat attacaattg
     8041 taatattatt gatttataaa aattacaact gtaatatcgg agggtttatt ttgaaaaagt
     8101 taatattttt aattgtaatt gctttagttt taagtgcatg taattcaaac agttcacatg
     8161 ccaaagagtt aaatgattta gaaaaaaaat ataatgctca tattggtgtt tatgctttaa
     8221 atactaaaag tggtaaggaa gtaaaattta attcagataa gagatttgcc tatgcttcga
     8281 cttcaaaagc gataaatagt gctattttgt tagaacaagt accttataat aagttaaata
     8341 aaaaagtaca tattaacaaa gatgatatag ttgcttattc tcctatttta gaaaaatatg
     8401 taggaaaaga tatcacttta aaagaactta ttgaggcttc aatgacatat agtgataata
     8461 cagcaaacaa taaaattata aaagaaatcg gtggaatcaa aaaagttaaa caacgtctaa
     8521 aagaactagg agataaagta acaaatccag ttagatatga gatagaatta aattactatt
     8581 caccaaagag caaaaaagat acttcaacgc ctgctgcttt cggcaagact ttaaataaac
     8641 ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt cttacttgat ttaatgttta
     8701 ataataaaaa cggagacact ttaattaaag atggtgttcc aaaagactat aaggttgctg
     8761 ataaaagtgg tcaagcaata acatatgctt ctagaaatga tgttgctttt gtttatccta
     8821 agggccaatc tgaacctatt gttttagtca tttttacgaa taaagacaat aaaagtgata
     8881 agccaaatga taagttgata agtgaaaccg ccaagagtgt aatgaaggaa ttttaatatt
     8941 ctaaatgcat aataaatact gataacatct tatagtttgt attatatttt gtattatcgt
     9001 tgacatgtat aattttgata tcaaaaactg attttccctt tattattttc gagatttatt
     9061 ttcttaattc tctttaacaa actagaaata ttgtatatac aaaaaatcat aaataataga
     9121 tgaatagttt aattataggt gttcatcaat cgaaaaagca acgtatctta tttaaagtgc
     9181 gttgcttttt tctcatttat aaggttaaat aattctcata tatcaagcaa agtgacaata
     9241 gcattttaca agtatttttt attgttcgat tagggtaaac ctaaataata cataaattat
     9301 attacaatat gtttattata gaggctaaag tatcttagaa atttggatag taggtttttc
     9361 gggaataaaa gtatagttgg ctttaatata taattaagct aagctatcat ttatatttac
     9421 tcgattataa ttcgcacttc aactttttta taacgtaaaa attaaaacgt agttttattt
     9481 atctttagta atatcttttt aaacactaca gtttcttcat tagttaaatt agcgaagtaa
     9541 tgattattaa gttgataggc tttcttttct aatgttggcc ataagtcttt tgctttattt
     9601 gtactgttta ttagcacagt tcttctattt tcattatcag tttgacgtgt tattagatcc
     9661 tttttggaca tcttatctaa tattccagat attgttgaag gttctaaatt taaagtatta
     9721 ccaatcgctt taggtgtatt caaattacta ttaatcaagc aattcaaaac accatattct
     9781 gctggagtaa tattataggg acttaataaa cttttaaaat gtttaaaaac tctattctga
     9841 gaagtactca acaaataatt tatacaatta tctaattcca caactaaaac ctctcttaaa
     9901 tcattagtat tgactcgctt atcatatcat gataagtttt gtaggaaaat agttttgcaa
     9961 caaaaacata cttctacaaa acaattgtga aagaaggcta ataaatgttc aatgcggtag
    10021 tagtgagaaa aagtgcatca aatgttagtt ataaagtaga aaaagttgat gaatctcatt
    10081 tatcgaaggg tgatgtatta gtaaaagtgg tatactcttc aataaattat aaggatatgc
    10141 tagctttaca atataaaggc ggtgtaatta gagattatcc tatgattcct ggtatagatt
    10201 ttgcaggtat tgttgaatca agttcgaatg ataagtttaa agaaggcgat aatgtattag
    10261 ttactggtta tgatgttggc gtgacacata caggtggatt ttcagaatat gcacaagtgc
    10321 ctggagagtg gattgttcct attccccaag aaatgtctat taaagagtct atggtatatg
    10381 gcacagccgg ttttacggca gcattatcaa tttttgaact agaaaaatat ggaatgaata
    10441 tcaaatcaca acctgaaatt ttagtgtctg gggctacagg tggtgtgggc agtgttgcta
    10501 tacaaatttt acataaaatt ggatatgaaa atatcactgc tatcgtaaga aaagaaaagc
    10561 aaatagaaat cgcaaaaaaa ttaggtgcaa aacaagtaat aataattgaa gatgataata
    10621 aaccgcttaa aaaaggtatt tttgattatt tcttagatac agtggggagt aatgtaacat
    10681 tatacggttt aaaacgtcta aattatcaag gtgttgctac tgtatgtgga aatgtagcag
    10741 gaaattcact taacgctaat atattaccgt ttattcttag aggtattaaa ttaattggca
    10801 ttgattctgt atatgttgat cataatatcc gtgaagatat atggagtaag ttagcaaatg
    10861 aatggaatat aggaaattca cttctataca atgaaattgg atttgaagaa ttctataaaa
    10921 cgatagatca gcttttaaaa ggacaacatt taggaagaac tattttaaaa gtataagtgt
    10981 gagtattcat taatacattt actattaatt caatcatttt gcatttctct actaaccagt
    11041 gttataattt atataacgaa aatgattaac aattaatgca ccaatcccca cactattgca
    11101 gtagtgtggg gattttttcg atgctggctt ataaagtcgc ctattaatta tttgttgcgt
    11161 ttactaagcc aataagtata atacgcaaca gcacagccac tgatgactgg tgctatgatg
    11221 tgaacgaaaa tgattagcaa agtaatgcac ctcctctctt cgtcaattga cgcctgagag
    11281 ataggcgact ctattattat accatctgtg aatatacaag catatctact tccgataagt
    11341 cgtcttatgt tatataactt tgttttttat agtatcaaga caagaagaaa ctcgtttcaa
    11401 aaaccctcat gatttttaga gaaaaactct cttatttcat cgtctttaat aaaataatat
    11461 gccatctttc catctttata aaaatcaagt acctcatttt tatataaaag ccttaaatga
    11521 tgtgaagttg aagcaacact cattttcaat atcaaagaaa tatcacaaac acacaactca
    11581 tcttctttaa tcaaagataa tatgattttc aatttcttct catcacaaat tttttctaaa
    11641 atgttaagta atttcttaga tttatcatct tctaaaaaac ttaaagcatt gttaacttta
    11701 tcctcatgta cacagatcac atcacaagta ttttcataac tcatataaaa tcacacccta
    11761 aattaaaata taaatcctaa aattgtttga atagtgtcat tttcaataat aataaataaa
    11821 cctaaagcta tataaataat agccataatc caacgactaa atttctcaac aatttctcca
    11881 attcctggaa tattagctaa tttttgtgca gtaaacacca agaagaaaat taaaattaaa
    11941 aagacaaaca gagtaagtaa taaattagta acacttaatg tcacaaaata cggaacaaat
    12001 aaaccaatat tatcggcgcc acaacttgct atcgtaacaa ttgcaaccgt accaactaat
    12061 ttagacaatc ctttttcatt caattctttt ttagctctct tttctccttc acaatcatca
    12121 taaatagcca ctttaattcc aagataaatt ggtattaaac ccaataaacc taatatccac
    12181 ttttctggaa cataatttaa tacaaaagct aaaaacaaac taactaatat taaaataata
    12241 gaccctaaat attgaccaac ataaatatct ctatattctt ttctagtctt tgctctagca
    12301 aaaaatatta ataaaattac taataaatca actgctgtag caatataaag aacagcagca
    12361 gcaacaaccg tttgaatcat aatacacctc attcaaaaat atttttgaat gtattataac
    12421 ttatattttt aaataatcat aggtgcttta ttccaattgc tttattgacg ttgagcctcg
    12481 gaacccttaa caatcccaaa acttgtcgaa tggtcggctt aatagctcac gctatgccga
    12541 cattcgtctg caagtttagt taagggttct tctcaacatc aataaatttt ttcggcataa
    12601 atgcgtgtct atgcgtagac atggagacac ttcagaatta tggagtgatt acatgagttt
    12661 aactattttt ctttattcag ttttaggaag tttattagca aattatatct acgaaaaatc
    12721 ttcaaaataa ataacttttt cggttctact ttgtacactt tatctacctg gtagacctaa
    12781 ttgttattgc tttacaggtc taaaattcgt cgttataatc tagttaaatc ccgtaagggc
    12841 gcacttatac gtcggataaa tcgacatgtg caaaaacgta atcgaccttc gtcgattttt
    12901 ttatttcaaa attaaagaaa cggcttgaga tattccgagc agttataaaa attaatttgc
    12961 gttgaatatt gctactacat tcttgaaaaa gtgatgtaga tttatagccc ataacttttt
    13021 tgaattacat cgacgatacg gcgtcgaaag aaaaataaat agaccgtatg aaagaaaaag
    13081 ctacctcact ttatctgggg tagcttttat tttttatgcc cttattttga attttaagag
    13141 ggcattttaa agatttaggg gtgattcata tagttttata tctaaaactt atatatgctt
    13201 ttaaaacgca aatatgagcc aaataaatat atgctatttt caaaaacaaa aatttgagca
    13261 aaaacaataa ctatttttag acactgccca tttacatgca aattaaaaat tagcataaaa
    13321 ttctttaaaa cttccccacg tttttctaaa ttcctgtagg gcgtttttat caaaaatcaa
    13381 gacaagaaga aactcgttca cactcgtttc aaaaaaacaa gaaatctaat ctatacacct
    13441 accgttttcc aaccccctca aagcatacaa attaaaaaca aaattattca taatcttact
    13501 ttcttttaac aaaaacataa aaaccataaa tagacaaatt aactatcaaa ggcaataaac
    13561 agtataaaaa aaccacgaat aaatcttcat caacatctaa aataaaaaag aataaaacaa
    13621 ttaacaaaat actaattaac aaacctaaaa gtggcaaact ttttatatat ttttctaaat
    13681 tttcattcat aaaatagact cctttcaaaa atatgtttat aaatatatta aaataaatat
    13741 tgattttata aagcgcttac ttatacaatt aaaatatctt attatcttgg aggtatcaaa
    13801 tgaaaattat aaaattattt tcaataattt ccttgttcct actggtattt agcgcgaatt
    13861 tttctaatgc ttacgcaaat gaagaacaaa aaagttcttt actagaaaat caaaaagaaa
    13921 aattgaaaag caaaaacatc gaagtatcac aaatgaccaa gaaagaaata agttttctag
    13981 aacaattgca aaataaaaat gaagatatgc aaaaattcga aaagcaaatg aaaaaagaag
    14041 gatttaaaaa aataaagcta gaagacaaaa attctaaatt aaaatatcta gctacagaag
    14101 caaatgataa aaatgcatat ggctacatag ctaataacgc ttataaaaat gaaaaaacaa
    14161 aagaaattgt agtttctgaa acaatatatg ataactacaa caaaaaaatc acaaaattca
    14221 ttgccgaaaa aagaagtatg actgaaaaca aagagggaaa aatacttatt aacaaaaatt
    14281 acgttgaata taaggctgaa aaagttgata aaaacagacc ggtaacatat gcaggattca
    14341 aatggaacgg caaagcattc gcttgtagta tggctggact ttatgcatgt gctcactact
    14401 gtggagtatg ggcaatcgta aatccaatag ccggcggtgt atgtgaagca gtttgcggaa
    14461 ctgcatttgc agctggatgc tctgtaggtt gattttattc caattgtttt attgacgttg
    14521 agcctcggaa cccttaacaa tcccaaaact tgtcgaatgg tcggcttaat agctcacgct
    14581 atgccgacat tcgtctgcaa gtttagttaa gggttcttct caacatcaat aaattttttc
    14641 ggcataaata cgatgttcct tatttatcct cataaaaaac aatagctgaa atatataacc
    14701 aattactgtg tgtttgaatt tctaatacat gaatatcatt ctttaaaaac ctattaactt
    14761 gtttatctaa ttgacgatga gtaaaagtag cgaaagtttt aatcttcatg atatctctcc
    14821 ttttataaaa atagcaatcc ttattacaat attaaacact tttattttgg attttaagag
    14881 gcattttgaa gacttagagg caaatcatat aggttttgta cttaaaaatc tatacagtct
    14941 cttaaaacgc aaatatgagc caaataaata tatgctaatt tcacaaacaa aaatttcagc
    15001 aaaatcagtg actaattttt tagatactgc ccatttacat gcaaatttaa aaattagcat
    15061 aaaatacttt aaaacttccc catgtttttc taaattcctg cagggctttt cttatcaaaa
    15121 acttagaaat tttaatttaa ctctaaaatc tccgtaagag cataagggaa atttgctatc
    15181 attcaaaaat gatagatctg gcaaggccag acattccaag ggttttaagt tattttaaag
    15241 tgatatcata caaagctgta gtgtcacact tttgtgacac tacatacagc atttgtcaca
    15301 aaaataagac agcacttttt tacagaaaaa caataaaaaa agacatcagt tatcactaat
    15361 gtcttaaata ataattttgc ttttcgaaat tccaaattgc ggtaattgaa tgtgcttttt
    15421 ttcttcgtct gtcgttttat cttcatcact tgtattaatc aaattaccat cttcggcatc
    15481 gtctaagttt aaaattttat gcttttgttt aagcaatcca ccataactta acatacgttt
    15541 tcgatacaaa cctttttcta aatcacttac aatttcttga tttttttcgt cgtcatcagt
    15601 taaaaagtca gatgatttaa cggaatattt tgatgtctct tcgagtgtta taaaatcatt
    15661 tgaattattg attaaagata ttatattgtt tcatgttttt acggcgcata taaagggcat
    15721 gtgtttcttc aagttcagtt agaattgttt gcattaaata agcttgcatt gacttgattg
    15781 tttccttttg gcctttaact cccctatcat gtatagcttt tttaagtctt tttaaagaag
    15841 ttaatatttc atcctcaatg tcctctaaca tgtaatgcat atcttcatgc cttgaattaa
    15901 atgatttttt tgctttaaga ataacagcct ttatgatttc taaatctcta taatcatatt
    15961 ttaataaata attagttagt tgttctggga attcttgcaa tagcatttct ttatcatcaa
    16021 aattatgtgt aaattgattt gaatgatttg aatgattact aatttcattt ttgtacttta
    16081 tatcattcaa gtcattcata tcattattct cagtatcatt aaagtcaatg tcattaaagt
    16141 cagtatcatt agtgttcgat tttcgaactt ctggacgttc gattttcgaa cttctggacg
    16201 ttcgattttc gaacttctgg acgttcgatt ttcgaacttc cttctcgccg taaggttcaa
    16261 catcgttttc ttctttttct attttgtaaa tatcacgttc tgtgacaata ggtttcatta
    16321 aatatagaat atttggttta tttaaaccac gtcgtttttg aatgagtaga ccatcgtttt
    16381 ctaacccttt ttttattttt gttaactttt cttttttaca atttaagatt tccattagct
    16441 tttcatttga ataaacaaag taaatgttac catcttcatc aacccagcta tttttaatag
    16501 ataaatttaa gcgatcacgt aagatagcat aggctatttt catatcatta gttagatttt
    16561 tataattttc actggtaaag aatactttag ggatttgata aaatctttct ttgtaatttt
    16621 cttgcactgt aaaatattga ttttgcatga caaaaaacct ctttccatat tttagtttgg
    16681 taagaggtaa taaaacgttt ttatttagct ttacatttat ttaatgattt aggtgcttgc
    16741 actaagatat tattcattat ataatacaag tatcgaaaat tatataaata aacagtttct
    16801 aaacgtttta ttaccaaacc ccgactatta ccagtagttg gggtttttgt tatattaagt
    16861 ttattatagc actttaaata aacttataaa agggaaaata tagctttatc aagggtttat
    16921 aaacccttga taaatatcat aaacctttca taaacccttg ataaaaaggt tgatggatgt
    16981 ttatttttat ttattaatca ctttattatt aagcattata agcttataat attttatcaa
    17041 gggtttataa acattttata aagggttgat gatatgaaaa gtgtgaaaaa gttgagtgaa
    17101 gaattagggg ttagtaagca aacgattttt aataatatta agcgattgaa tatagagaca
    17161 ataaaacagg aaaacacttc gtttattaaa gaagataccg atatagaaaa aatcattcaa
    17221 agagtaaatg aaaataaaaa gaaatatggt tttgaaagta ctactgaaga caaacaaaaa
    17281 aaagggtcgg ataatattaa ttttgaatcg aaaagcgatg ctcaaatagt agaaatcctt
    17341 aaaaatcaga ttgatacttt aaataatcaa attgaaaaac aagaaagtcg tcatgaaaca
    17401 acaattgaat tttacagaaa agagttgcaa gaaagatcaa aattgcttga aaatcagcaa
    17461 gttctggcat tagagagtaa taaaaagatt caaaaattag aaaatcaatt agaaaaagaa
    17521 aaacacctta attatccctt tgatacatct actaacacta gacaaaacgt tgatgcacaa
    17581 gaaaaaacat atactactaa tcctgtaaat attaacagag atcaggaaga aactaaagaa
    17641 acagagattc aatataagga tatatctgga agtcaaagcg acgaaagtac acaaggtgaa
    17701 gaagcaaaaa aagaagacgt tccagctaat ctaaatgaca atgatagtga tatagaagaa
    17761 aagagtgaag aaacggaacc taaaaagggg ttttggagtc gtttgtttgg tagctaaaat
    17821 aattgattag gcactaaaag ttataaaatt ttagtgtctt ttatatagtg agaacttctg
    17881 gtaatcatcg attatgtaaa ctaaagtatt tcaaataatt aactgtatta atactctcat
    17941 catgattgcg ttataaacgt tcgttattga gacaaaattt aatagtacta ctacacaaaa
    18001 agagagtgcg aattcgcact ctctttttgt gataaatgaa tggttaagaa aataattcat
    18061 ccacagttgt atcaaacaat cttgccaact taaatgctaa tgtcaatgta ggatcatatt
    18121 tattgttttc tattgcatta atagtttgcc tagacacttt taattcttta cttaaagttt
    18181 cttgagaaat tcctttttgt tttctatatt ctctaattct atttttcatt aatttaacct
    18241 ttagatgtat attttttatt tgtagtatag taattaaaca gcataagaaa tagtgctaca
    18301 attataaaga aaatttctgg atattgagaa aaccaagatc cttcaatact tggtgacaaa
    18361 cctgtaaatt taagcactag tgtaaataac atacaatata caatccaaat aaaactttta
    18421 gccagtattt caataaacat tttacgttgt ctttcatcgt atcgatcttg ttgtcctttt
    18481 ttatctaatg tttctgaagg taaatatttg ttagttatag ccgtccataa acaagaaaaa
    18541 attaaaataa taataaaagg aattaaattc attataacac ctcataaaca cctcataaat
    18601 gtaaaaagta tttgacattt atgagtgtaa atatttttga tacaaatgtc aaatactttt
    18661 tacattataa tatattttaa aacaccttat tagtaaaaca attactatat agaaagctgc
    18721 gaactcgtac tcttttttct tgtataatta ttaaaatctc aattcaataa tatgttatgg
    18781 aatttgagac actgtgagag acgctcattt gcattgacaa tcaatttatc aagataatcc
    18841 cttatcatgt ttaattctat aaactgtttg tcttgtgata ttaacttctt tcgcaatctt
    18901 actaatcgct ttgccttctt ctaacatttc caccacgcga tgataaataa cacgtttctg
    18961 tgggtcttta gcatttggtg aataaagtaa agggcgccct ttatatacgc ctttttcctt
    19021 cgcaacttga atcccttgcg cttgtcgacg tttactttca tttctctctt gttctgaaac
    19081 cattgctaat atttgaatga ttaaatcttt cataaactta tccagtaatg gattgccaat
    19141 tacttcattc atcataggta agctggtaat cattaactga acgtcttttt cttttaaata
    19201 attcacagtt tcaataattt catcatagtt acgtcctaaa cgatcaatag attccacaac
    19261 gaatcgatct cccattctga caaaattgag tgcttcttga aatacaggtc tattttccac
    19321 tgactttccc gactgtttct ctgtaaagat tttctccaca ccaaacgtct ttaaattatc
    19381 caattgtctt tctaaatttt gatctatcga tgatactctc gcataaccta taatcattca
    19441 tcttcactcc ataataaata tacaccctaa tcatacgttt taattgttat aatttcaaca
    19501 attctttttg tatggttagg gtgtactcaa agtgtacata tctataatta aaacttacta
    19561 aaaataaata tagatttttt ctttgtaaca gaaccgttca tttgaaggtc atctctatca
    19621 taaatattta aattaactaa aaattttaat catctgttta atacttatga aatgtattta
    19681 cggtaggtat taaaattgat gaaatttata taagtgcttt caatgaaaat gaccgtttat
    19741 ttatcctcct gatttaagga gttagaaatt tcgaaaacga ttctttccat ttgttgcatt
    19801 tgttccatgt ccagatattt aatacattat agaaaaccaa agaccatcac taattaaacg
    19861 cagttttaaa atttcatcag gattgccttc gtctttaaaa tgggcctctt ttaatataag
    19921 ttctactctt tcatacctaa ctctttcaat gccatcgttt catacgccga ttctcctgat
    19981 tccatagcaa actcagcgat aaacattggg aatactgcat tgagttctat tatatgctct
    20041 ttcattcgtg gccatatttc acctccagct ttaccgtatg ctgttataag ttgctctaat
    20101 ccttcgtcgt cgaatacacg atggtgtcct ataaagtcca ttgatgggtc ggagtgggtt
    20161 gcttcagtcc agtctatgag acctgtgacg tttgcttggt tatctaccat tatatgtcct
    20221 ggatgtaagt ccccatgtat catggtcgca tgtcgaggcc atagttcgtc gttttctaac
    20281 cattgtttcc atctgttcca taattcatct gatacgccat aagtttcttt aactttattc
    20341 attcttcttt gaaagtcatt ttttatttct tgtatggttt tgatatttat atgctgaacg
    20401 ttaatgtttt cttctggtat gttgtgtaaa tctacgagtg tttcagctaa tgtgttaata
    20461 aagttttctg gtaatggttt gtgttcaatt tcccatacat aattttgtat ttctggatct
    20521 attgtggctg cgggtttacc tgtaagtttt gggtaagcaa taaggtcttt tgcatgtact
    20581 ttccacttcg gtatttcaaa tgaaacattc ttctgtaaga agtctaccgt ttgtttttcg
    20641 ggttttgttc gtttataaac gtcaggtctt cttggtagtc tcaaaaccca ttctactcca
    20701 tgtttatctt ttccaaatgc aacttgaaaa tcaagtcccg attcattcaa tgagattgtt
    20761 tgaggttgga tgtgtaattg atatttttct gcacatttaa taatttcatt atgtcgagtc
    20821 attttattgg atccttattt ctattatatt tttcttgtga acgtattttt tatattgata
    20881 taaatgaacc taatattcaa tataaattag tgtatagttt ttaagttata tcatgaagag
    20941 attgtcctgt taattcccat tttttatctg atacatgttt aacaaacctt gtatcatgtg
    21001 atgtaaacaa aatgattcca ggatatttat tcataaacat ttctaatgct tctaatgttt
    21061 taatatctaa aaaattagtt ggttcatcca aaattaacat attcgctttc gttgaaaata
    21121 atactgctaa cgataatttc gttctttccc caccactcaa aacattacaa gaacgatcaa
    21181 gtgcttcatt taaacccaag ttatttaaaa tagctctact gaatgattct gatgaatccg
    21241 tttcatccat taaatattgc aataatgaaa cgtcacgcat gtcttcataa gcaagttgac
    21301 gatagtatgc catttgcact ttaggagaac aatcaattcc ctctatttgg tggtaaatag
    21361 cttcaagtaa agttgtctta cctacaccat ttgcacctac gagcgctata tttttgccat
    21421 atggtatttg gaatcgtact tgtgttagca gtttttgact tcctttaacc aatgttagat
    21481 tttgtgcaat gattggataa ttattatgga tatcataaat tttattttgt gggaaattga
    21541 attcatgata actttgtggt ttttcaactt cttccaaatg ttccattctt ttttcaatat
    21601 gcttagcttg tttttgagca gccttctcaa ccgtgccttt ttgttttgat gcacttaaac
    21661 gatctggtgc tatacttttg tttttttgtt ttgatgatgc ttgtgccatt tgttgcgctt
    21721 gatttcgttt agctttactg gcttgggaca atctttgttt ttcacttata tactgttcat
    21781 attgacgttg ttgttctaac tgttcttgtt catattgatt ttgatactgt gtgtaattac
    21841 ctttaaacac tcttattgtg ccatcttctt gtatatccca aattgtgtca gcaatttggt
    21901 ctataagtgc tctatcatga cttactataa ttaaagtacc atagtaatat tttaaaatat
    21961 ttttcagata atctttacca attttatcca agtgatttgt aggttcatct aaaagtaata
    22021 tcggactata atttgatatg acattagcta atttatattt tgctttttca ccaccactca
    22081 tactgtcggt tgtatgcata ggtatatgga gttcactcat taaactaccg tctaacgtgt
    22141 taaaatcatt ttccacatcc atgttaagct gttcaaaata ttgaatttcg ccaaccgttt
    22201 caactgttcc agattctggt tttgtttttt gagcaatcat atttagtaat gtggttttgc
    22261 cagtaccatt acccccaata agtgctattt tttcaaattg gtaagcgtaa agatgaccga
    22321 tgttaagtga tcgtaaatct gtcaatttat gattgatttg gttaaattta attgtatatt
    22381 gttccatatt tatacactcc ttgtatattt aaaggacgtg tacgcaaaaa aatgagacag
    22441 gctactcccg tctcattcac attacacttt caaacactta aaaatttatt atgatgtttt
    22501 agtatttgaa agcgtttatt attcctatcg aaggataaaa aatgacataa gtcatcctat
    22561 gagtgtgtat tgcggacaag cctttttgaa ttaatttagt tttgtattca aaaaggttta
    22621 tttgagtctc atagaagctg tcattttaat cctccttcat cgataaaata gtaatgttaa
    22681 tataacattt tgttggtttt tttacaatat atctctaagt agaaagatta tataacaaaa
    22741 gtataaaaat acaattttag attgattata catctcctta atttagagtg tactcataaa
    22801 atacggttct gttgcaaagt tgaatttata atataatttt aacaaaaagg agtcttctgt
    22861 atgaactatt tcagatataa acaatttaac aaggatgtta tcactgtagc cgttggctac
    22921 tatctaagat atgcattgag ctatcgtgat atatctgaaa tattaagaga acgtggtgta
    22981 aacgttcatc attcaacgat ctaccgttgg gttcaagaat atgccccaat tttatatcaa
    23041 atttggaaga aaaagcataa aaaagcttat tacaaatggc gtattgatga gacgtatatc
    23101 aaaataaaag gaaaatggag ctatttatat cgtgccattg atacagaggg acatacatta
    23161 gatatttggt tgcgtaagca acgagataat cattcagcat atgcgtttat caaacgtctc
    23221 attaaacaat ttggtaagcc tcaaaaggta gttacagatc aggcaccttc aacgaaggca
    23281 gcaatggcta aaataattaa agcttttaaa cttaaacctg actgtcattg tacatcgaaa
    23341 tatctgaata acctcattga gcaagatcac cgtcatatta aagtaagaaa gacaagatat
    23401 caaagtatca atacggcaaa gaatacttta aaaggtattg aatgtattta cgctctatat
    23461 aaaaagaacc gtaggtctct tcagatctac ggattttccc catgccacga aattagcatc
    23521 atgctagcaa gttaaacgaa cactgacatg atatattagt gattagctat attttttact
    23581 ttgcaacaga accagccatt taatatgact gttacaatta ctaagattca agcactatta
    23641 cgccgcacgt atgatttcac cactcaagtt aataatttaa cagtagatga ttgcgagtta
    23701 ctacttgatg cagcaaagct taaatttaat gaagaaacca tagacctgac acacactgaa
    23761 ttgcaaatca tgcatagctt attccagaac aagggcaaat tcgtcagtcg taatgcgtta
    23821 atcgaaaaat gctgggaatc agaacacttc attgatgaca atacgcttgc tgtcaacatt
    23881 acacgtttac gcaaaaagct acaaaaacta ggacttacag attttatcga aacgaagaaa
    23941 aatgtcggat atcgtgtagg tgacgtatga atttcttgaa atcaatccaa cgtgaaattt
    24001 atattgtcat ccttacttgt gctttattct actttatatt attcatgtat aatgtgccga
    24061 tgcaagcata tatgattggt ctaggtattg tattgtttgt ttcaatgatt tactggggta
    24121 tccattacat gaactttaaa aaagaataaa cactacagga acagaacgaa gatttaagaa
    24181 tcgaaaacca taaacttcgt aatgacttta ttaactacca aagtgagtta gagtcatatt
    24241 ttttaatgtg ggtgcatcaa atcaagacac cgattacagc atcaaagtta ctgcttgaag
    24301 atcctgatga acacgtgatt tctaacgtgc gtaatgaagt cttacaaatt gataattaca
    24361 cgaatcttgc actgaactat ttgaaactca tgaaccaaaa gacatacatg gtctttatgg
    24421 aagtgagtgt agatgaatta attcgaccac tgattaaacg ttatgcgata cagtttattc
    24481 atcatcaaac aaagttgcat tatgagaaaa gtgaagcggt tatattaaca gatgccaaat
    24541 gggcatcaat tatgattgag caaatattaa acaatgcatt aaaatatgca cgtggcaaag
    24601 atgtgtggat tacgtttgac gaaaatacaa agaaattatc aatccgagat aacggtatcg
    24661 gcattaatgc gagtgattta ccgaaaatct ttgataaagg tttctcgggc tataacggta
    24721 gaataagtga gaaatcaagc ggtattggtt tatatattgt cagcacaatc tcaaagcgct
    24781 taggccataa agtaagtgct acatctacat taaacgatgg ttcaatattc accattcaat
    24841 ttaaataact ccaatctttc atttttgtaa gattagcggc tgtttttgta agaatagata
    24901 aaggcagcct tttctaatcg cgcgtaagat aaaggtaaca acaaactaag aaaggtgcca
    24961 gaggtgaaaa atttgaataa tataattgaa ataaataact taacaaagca atatggaagt
    25021 cagatagcag ttaataattt gagtataact gttgaaagtg gacaaattta tggtttttta
    25081 ggaagaaatg gtgcaggcaa aacaactact ataagaatgc ttttaggctt aattaaacct
    25141 acgaaaggta atattaaaat atttgaaaaa gagttcgaaa gtaataaaac tgaaatttta
    25201 aaaaatattg gtgctatggt tgaaacgcca ggtttttata gtaatttgac agctaaagag
    25261 aacttaacta taaatgctaa aatattaggt atacaaaaag aaaatgcaat tgaagaagtg
    25321 ttagaaatag taggactagc ttctgaaaaa gtaaaattgt ttaaaaatta ttctttaggt
    25381 atgaagcaac gtttagggat tgcgagagct ttattgcaca atcccgaatt attgatactt
    25441 gatgagccga cgaatggatt agatcctatt ggcataaaag aaattagaaa gttgattaag
    25501 gatctggctc aatctagaaa tataaccatt ttaatttcaa gtcatatatt gtcagaaata
    25561 gagcagttag tagacaaggt gggtattatt cataacggag ttttgttaga agaaattatg
    25621 tatgaagatt taaaaaaaaa gaacagacaa tttataagta tatcagtatc agatgaagaa
    25681 aaagttgcat gtttgttgga aactaacttc ggaatttatg actataaaat taaagaaaat
    25741 ggcgaattta aaatttattc acatattgat agacaacaag aaattaatag attattagta
    25801 ttaaacaata ttgatgtttt ccagatgaga gtgatagaag ataatctaga aacttatttc
    25861 gaagacttag taggaggtgg cacaattgga taatctactc cgtacagaat ttattaagtt
    25921 aaaaagatca tatatgtttc taataagtat tttaggtaca tgcgtagcac cttttatggt
    25981 ggttgtagct tcttttatta gtatgcggac gaaagtaccg actcctaata ttgtatttaa
    26041 acagttattt gaagaagtca gtttatatca tatgctaatt attggacctc ctctatatgg
    26101 ggttataata gcctatttgt ttggaagaga atatatagaa gatactttaa aaaacttatt
    26161 aattatacct atatctagag aaagtttttt agtaagtaaa ataatattat tattcttgtg
    26221 gattcaaaca ctatctgtta ttgcatggtt gctaacttta atgctaggta tgctattgca
    26281 ttttcaaggg ttaagccaga gtttaataat tgattcattc tttacatttg ttattggcgg
    26341 agtgttatta tggatattat ctccaccaat aattattttg tcgatatatt ttaaaaatta
    26401 tgttcccaca attgttttaa ccataataat tactttgata aatttaatga ctgctaattc
    26461 tgaacataga ggattatttc cttgggctgc agttggagac atatctagag gaacattacc
    26521 taatacttat ccatttctat tatctttaat tatcataatt gttacatcta tattcagtgt
    26581 aattatatta ttctcatact ttaaaaaaac tgatataagt taaaaggagg agaaaaatgg
    26641 gttttataga gcagattaaa gcatttattt taggtgtagt tgaagggttg acagaatttg
    26701 ctccagtatc atcaacaggt catatgatta ttgttgatga tatgtggtta aacactgctg
    26761 acgatttagg aagtgcgtct gcaactactt ttaaggtggt aatacagtta ggaggttctg
    26821 ttgcaaagtt gaatttataa tataatttta acaaaaagga gtcttctgta tgaactattt
    26881 cagatataaa caatttaaca aggatgttat cactgtagcc gttggctact atctaagata
    26941 tgcattgagc tatcgtgata tatctgaaat attaagagaa cgtggtgtaa acgttcatca
    27001 ttcaacgatc taccgttggg ttcaagaata tgccccaatt ttatatcaaa tttggaagaa
    27061 aaagcataaa aaagcttat
//
