LOCUS       NZ_CP151678            26817 bp    DNA     circular CON 24-APR-2024
DEFINITION  Proteus mirabilis strain P3 plasmid unnamed2, complete sequence.
ACCESSION   NZ_CP151678
VERSION     NZ_CP151678.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN37689396
            Assembly: GCF_038403595.1
KEYWORDS    RefSeq.
SOURCE      Proteus mirabilis
  ORGANISM  Proteus mirabilis
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Proteus.
REFERENCE   1  (bases 1 to 26817)
  AUTHORS   Sattler,J., Stelzer,Y., Schaefer,S., Noster,J., Peter,S.,
            Goettig,S., Gatermann,S.G. and Hamprecht,A.
  TITLE     Analysis of the genetic environment of blaOXA-48-like carbapenemases
            in Proteus mirabilis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 26817)
  AUTHORS   Sattler,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2024) Institute for Medical Microbiology,
            Immunology and Hygiene, Universtity Hospital Cologne,
            Goldenfelsstrasse 19-21, Cologne 50935, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: flye v. v2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_038403595.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 12:42:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,217
            CDSs (total)                      :: 4,108
            Genes (coding)                    :: 4,022
            CDSs (with protein)               :: 4,022
            Genes (RNA)                       :: 109
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 26 of 86
            Pseudo Genes (incomplete)         :: 65 of 86
            Pseudo Genes (internal stop)      :: 15 of 86
            Pseudo Genes (multiple problems)  :: 15 of 86
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP151678.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26817
                     /organism="Proteus mirabilis"
                     /mol_type="genomic DNA"
                     /strain="P3"
                     /host="Homo sapiens"
                     /db_xref="taxon:584"
                     /plasmid="unnamed2"
                     /geo_loc_name="Germany"
                     /collected_by="National Reference Centre for
                     multidrug-resistant gram-negative bacteria for Germany"
     gene            join(26638..26817,1..825)
                     /locus_tag="RZR84_RS20915"
                     /old_locus_tag="RZR84_20915"
     CDS             join(26638..26817,1..825)
                     /locus_tag="RZR84_RS20915"
                     /old_locus_tag="RZR84_20915"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_082242808.1"
                     /translation="MSIADYGSLSNQKRLEQRQFNQHKILSFLAQERSVTIDSLSRLFD
                     FSANQKIYLLLKNLINNELVTYFEDGFLGRTKRFYHLTAQGQAFAEQELGITPRFNGLS
                     RRAHAPSALLHTLEMQNYTALLMKAGAKVRYLHLPDKIMDYWYGGTAAEVERTFKSQKR
                     YRDIFRNYCLRMRRNDPIINTVMYILPDSAMRDKAAALFYSFDELMIEGILTDVRTYTG
                     RFLFATRAEYEAYLTAFPQSGVRVEMKLPNEVWQRWQRHAAQAQLTPEAWLTGILNREV
                     PVVINEPMPYSGDGVLINLTPTKDDYKFWLANADACHTSLSAWCAGKPVHLNL"
                     /name="hypothetical protein"
     gene            complement(855..1100)
                     /locus_tag="RZR84_RS20920"
                     /old_locus_tag="RZR84_20920"
     CDS             complement(855..1100)
                     /locus_tag="RZR84_RS20920"
                     /old_locus_tag="RZR84_20920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005370427.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_029403600.1"
                     /translation="MIPERLKTARKKRHYTQELLAIKAGIDESTASSRISQYENGYSVP
                     SYQLMQKIASILQIPTCYFYCDDEELADYLINYYRR"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(1157..1477)
                     /locus_tag="RZR84_RS20925"
                     /old_locus_tag="RZR84_20925"
     CDS             complement(1157..1477)
                     /locus_tag="RZR84_RS20925"
                     /old_locus_tag="RZR84_20925"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_029403601.1"
                     /translation="MKKNFFEYIEEAKKLTICDSYRKIAQYLDAPPIKISQWKQGKGYV
                     SPAECAHLARLLGITTEEIAYVIKAEREEIPEKKEYWYKEAEIFSRPINPPESLKLKNK
                     KS"
                     /name="hypothetical protein"
     gene            1583..2116
                     /locus_tag="RZR84_RS20930"
                     /old_locus_tag="RZR84_20930"
     CDS             1583..2116
                     /locus_tag="RZR84_RS20930"
                     /old_locus_tag="RZR84_20930"
                     /inference="COORDINATES: protein motif:HMM:NF021981.4"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
                     /protein_id="WP_157673318.1"
                     /translation="MITNNTLKRKFLNTLLFFGVLSGCVMLYQHYFVVNFTKSMPLGVY
                     FKSYPASYTKNDTVLVCLDDEIARWSVDHHIIADGLGCRHSAPLLKKIVATEGDRVTVT
                     HKGIVVNDVLVPNTAPIARKIKQWNIIDREILLKSTEYIVVANQNNLSFDSRYFGVVTD
                     RNITAKIRPFYLFD"
                     /name="S26 family signal peptidase"
     gene            2207..2746
                     /locus_tag="RZR84_RS20935"
                     /old_locus_tag="RZR84_20935"
     CDS             2207..2746
                     /locus_tag="RZR84_RS20935"
                     /old_locus_tag="RZR84_20935"
                     /inference="COORDINATES: protein motif:HMM:NF013618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_135180852.1"
                     /translation="MPSVSACAPEIAADTLQKIIMVESGGNPFAVNVNKLSAGSQPKPK
                     NVADAVAATQYWIAKGYSVDVGLMQVNSRNFKMLGITDTDLGSVFEPCNNVKYGATILL
                     SAWNMTSSKEHQNDRLMKSLSIYNTGNDVNGFKNGYVSKYVGRNISGSLAKTVVTPYNA
                     DSSVGFNADSFYGDDL"
                     /name="lytic transglycosylase domain-containing protein"
     gene            2743..3687
                     /gene="trbB"
                     /locus_tag="RZR84_RS20940"
                     /old_locus_tag="RZR84_20940"
     CDS             2743..3687
                     /gene="trbB"
                     /locus_tag="RZR84_RS20940"
                     /old_locus_tag="RZR84_20940"
                     /inference="COORDINATES: protein motif:HMM:TIGR02782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer ATPase TrbB"
                     /protein_id="WP_087726755.1"
                     /translation="MNTGDDKKISDLAKMLWREFDIIAPYLRDETTIEIMLNPDGKIWV
                     EQIGKPMFSIGEMSLYNAQSLFATIAHSMGKTIDNRHPCLEGTLLINDARFEGFYPPVS
                     SAPTFAIRKKPKKIFSLDDFKLTENQKSTMVTWVKERKNILVVGGTSSGKTSFSNAFID
                     LMAQFTPDDRIVILETLDEIQCRAKNYSKLIETMDVTMNQLLRGVMRYRPDRIIVGEVV
                     DAAALSMLKAWNTGHDGGLCTIHADSALEGFDRLYDLIEESGINMSERVNRLIGRAIDG
                     VVFLKREQGVRVVKEVANVTEFNGSEFVLDYVN"
                     /name="trbB"
     gene            3697..4056
                     /locus_tag="RZR84_RS20945"
                     /old_locus_tag="RZR84_20945"
     CDS             3697..4056
                     /locus_tag="RZR84_RS20945"
                     /old_locus_tag="RZR84_20945"
                     /inference="COORDINATES: protein motif:HMM:NF016820.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_087726754.1"
                     /translation="MLEKYYYSQSRLTQQLIVLGALLLVCMLLSSHAMAGQTQGLPWES
                     PLDKIKNSITGPVAGAISFLGICVAGMMLIWGGEMSDFTKRIVYVVLVISLILGASVVI
                     NMWQGNGALIPLSMV"
                     /name="TrbC/VirB2 family protein"
     gene            4062..4382
                     /gene="trbD"
                     /locus_tag="RZR84_RS20950"
                     /old_locus_tag="RZR84_20950"
     CDS             4062..4382
                     /gene="trbD"
                     /locus_tag="RZR84_RS20950"
                     /old_locus_tag="RZR84_20950"
                     /inference="COORDINATES: protein motif:HMM:NF010395.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbD"
                     /protein_id="WP_032300801.1"
                     /translation="MKTQEPLVSFIIHRSLNRPDLVFGCERKPLYCLGLIAAVMIFSSY
                     NLYIAGAGLVVFCVGVYLLRRMAKADPFMSLIFQRAIRYRYYYPARSTPFATGAKFRRK
                     KQ"
                     /name="trbD"
     gene            4379..6880
                     /locus_tag="RZR84_RS20955"
                     /old_locus_tag="RZR84_20955"
     CDS             4379..6880
                     /locus_tag="RZR84_RS20955"
                     /old_locus_tag="RZR84_20955"
                     /inference="COORDINATES: protein motif:HMM:NF015118.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_082242806.1"
                     /translation="MKLYKKQYNTSLSFADLLNFGVMITPNLMLGKDGSLTAGLVYTCW
                     DYENSDNSELNDLVNALNAAYLRLGTGITLHFTVIRSETSEYPQPEKSHFTSLLNKLID
                     EERRIKWESAGAHFSSVLSFSITYLPESMSKSRLSDFFVTDESGTKKSKSLTDKHIEYF
                     ESVISELSGQLSGTFTLHRLGVRHDNATGVVYNDLVQYFNHCISGDNYPVIHPDNQFLD
                     AVLSTDDFYTEPRLKIGNKYISVLCIDAYPASSVMGMLQSLSNLPCEYRWTTRAIFLDP
                     IDADKQIEKYRKSWGQKVRGFVDQLMGKHSDNINYDAATMKEDAQIAKGENNSNTVRYL
                     YLTPTIVIMDEDIDRLDETTNLIRTTIKNVVNFNARIETVNAMDAYLGSLPSHTYENVR
                     RPLLHTGNMTHIVPCSTLWTGEETSPCPFFPPDSPPLMKVSTTGNSEFNLNLHEDDVGH
                     GIIGGKTGAGKSSLVTLISSQYDRYPDSQVFTFDKGRSAKVFCKLSGGKYYDIMTGEHS
                     LNFAPLARIDEPSEFIWAFEWLQDIAEINGVKLDSEKVKKLNEALKIVSRMDNKDGQYR
                     NIDSLITKLQDRELKDLFSQYGSGGAYGEVLNQPQEQITLSNFTVFEYGELLDRGNKIK
                     LPVLFYLCHLIERQLDGRPTLVNIDEAWKFLDEPVAGKRLLQWLREWRKSNAAVVISTQ
                     NLHIIEKAFPLVFSEIAMACPTKLFLSNPAAEEEVSINAYKILGCKAAEIRRIRHLTPK
                     REYFVKKGDFRRTFSLDMVEGDIGLATVAASSKKDLKEIDKLDFEHSSEEELLHQWLDF
                     KGVDSGYVQYLTDRLKSRGEI"
                     /name="hypothetical protein"
     gene            6877..7605
                     /locus_tag="RZR84_RS20960"
                     /old_locus_tag="RZR84_20960"
     CDS             6877..7605
                     /locus_tag="RZR84_RS20960"
                     /old_locus_tag="RZR84_20960"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726753.1"
                     /translation="MKKILIAGVFAISTFTTLNSFAWHGVATEGTQWLNNLQLVKQVEE
                     QMRTVKNQIQDLQRLPSDVLNMGSNKLKVLETFNDLKRIYQEGQNIAQAGRDVAKYYKD
                     MGNIDIADALKNGNYPQLFNQWSHQNHDTVKGILEQNKLSMDWFNDRQGEVAGYNSMLN
                     SADGTVSALQAAGKIANAQLDSLSQLGQLQMAQNNLLASQAAVQQSEKDAERADTIRRS
                     EMNVIINSDNNTAADFLKRD"
                     /name="hypothetical protein"
     gene            7608..7850
                     /locus_tag="RZR84_RS20965"
                     /old_locus_tag="RZR84_20965"
     CDS             7608..7850
                     /locus_tag="RZR84_RS20965"
                     /old_locus_tag="RZR84_20965"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726752.1"
                     /translation="MKLITTGLSFFLIITVVSTGYLWKQNKELHYQINELSTVVAEQRV
                     AVQGCLKEKTDTQHRGKANFVIPDDSGNAEDWLKR"
                     /name="hypothetical protein"
     gene            7869..9476
                     /gene="trbL"
                     /locus_tag="RZR84_RS20970"
                     /old_locus_tag="RZR84_20970"
     CDS             7869..9476
                     /gene="trbL"
                     /locus_tag="RZR84_RS20970"
                     /old_locus_tag="RZR84_20970"
                     /inference="COORDINATES: protein motif:HMM:TIGR02783.1"
                     /GO_process="GO:0009291 - unidirectional conjugation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbL"
                     /protein_id="WP_087726751.1"
                     /translation="MKKIIFLFCVLLMPFLTHLAYADDVSGLTGEWKSPEEVRRLIDES
                     RRETALINQYTNECAKGNNQSCIQLETIKSKNSKINLDANFVKTFSDSFQQEIKKWLPP
                     LQKAAKYLLFTLGIIALVLKMVPLVLKGADLGEIIKELIIFVLIIGIWLAFIINAKEWT
                     DAIINSFMKLAQLANQTSMQATPVGILKQGFIVVGKVFTDPINPITLLTQVICALIIMI
                     IYAKIAFYLLKVMLETYIVSYGGIILLGFGGIAFTSDYAKRYFTYVISCGIKLFMTLLI
                     IGFGGNFIASFLTLNFTEFANCVAIVAVVVMLMMLAEGIPDMAQSMVTGASLGNSNMNI
                     GGSLATMAAAATAFTAACYAGAAAFKAAGAANAAGGGGAATGGLSGGDLANALSKGGGS
                     GVAGGGGSGGSSSLPNGGKSGAQLVKEGKVQSPNKNTGNTATGTESGKPQQSRTGAALK
                     AVAKSVGEGILNKAAGSRGSTAANITRAALNHAAQSQQSTESPRKPIASPYAKSTGNNS
                     SGTSKMPNKGNNDTGENQ"
                     /name="trbL"
     gene            9473..10117
                     /locus_tag="RZR84_RS20975"
                     /old_locus_tag="RZR84_20975"
     CDS             9473..10117
                     /locus_tag="RZR84_RS20975"
                     /old_locus_tag="RZR84_20975"
                     /inference="COORDINATES: protein motif:HMM:NF016238.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_071434332.1"
                     /translation="MSDDKFKKSSGWNSFLGKTKEQVTFYRWTTILCAVAAIISISGCI
                     YFSSQVKYVPFVVEVNKEYAPLQVHQLESLGQSKDAVTRSQLATIIKNMRVVYAGDKEA
                     QLDAIKSVYYFIKTNSQPYKYVQEMFSVDDPMNQKFLNQVEIKAILPLSKDTWRAEWVE
                     KKAMPDGKNVLSRNYSAVIQVEYADTISAEMIINNPIGLYLKNMQITEEYK"
                     /name="type IV secretion system protein"
     gene            10129..11043
                     /gene="trbG"
                     /locus_tag="RZR84_RS20980"
                     /old_locus_tag="RZR84_20980"
     CDS             10129..11043
                     /gene="trbG"
                     /locus_tag="RZR84_RS20980"
                     /old_locus_tag="RZR84_20980"
                     /inference="COORDINATES: protein motif:HMM:NF015487.4"
                     /GO_process="GO:0009291 - unidirectional conjugation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbG"
                     /protein_id="WP_087726750.1"
                     /translation="MKKTILFTSLLISGVALADPVVPSVSNIERINTGATSQPTTPQQA
                     MPSSMLLGGKDLPLSRKEQQAIKTANQWVNGKQYISNGGQEVVYTYGAGQAAIIATPLK
                     LSVFELESGERIVNEGIQLGDSVRWHATPVKQGNQTNVIIKPTDTGLSTDLVVVTDRRT
                     YHIKLISNSKNYTPLVKFSYPEDENQKAWNAYYQNSGADNSSISLAGNKTGLAPVNFDY
                     TIKGDNKMKPLRVYDNGSQVFIQMDGKLQETPALFVINGSGKQQLVNYRYVDNTFVVDR
                     LFNKAVLTLDVGGDQEKVTITKG"
                     /name="trbG"
     gene            11047..11493
                     /locus_tag="RZR84_RS20985"
                     /old_locus_tag="RZR84_20985"
     CDS             11047..11493
                     /locus_tag="RZR84_RS20985"
                     /old_locus_tag="RZR84_20985"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726749.1"
                     /translation="MKYKLFFAFVCMVLAGCVSKPNISSYDGTQGTIGKNSVQKMLYGV
                     DVIFSKLHSKNTIFYIEDSHSDIANAFIENIKRKGFIVIVTNKEDKINYKKINMGMIVK
                     KITPDIYSLSIITDKYRINQPYDYQLNKIGEVSIQNKTEDVNHG"
                     /name="hypothetical protein"
     gene            11486..12700
                     /locus_tag="RZR84_RS20990"
                     /old_locus_tag="RZR84_20990"
     CDS             11486..12700
                     /locus_tag="RZR84_RS20990"
                     /old_locus_tag="RZR84_20990"
                     /inference="COORDINATES: protein motif:HMM:NF015688.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="WP_157673317.1"
                     /translation="MANPSQNKKLTKKQKLLMTIGFAAVLIIFVVFISIMSLGTNTDSQ
                     TQSYEDAKDKSGDPADPSYEANLYRSRFRENTDLQTPPATPDKAPSATGTIQTANVSQP
                     QSNSTQTQSQERDQFAENVLRMKQQAYMEALNSKTTVRVDALSDNNSPERGSSAPDYAS
                     IAEQLAAASKEGNGELYANMQQNKEKFVNTERTFGYSTQTREAALSQTEIKAGMILPAV
                     LVTEINSDLPGLITAQITEDVRDSLTGRKILIPRGSKLIGSYDSQVAMGQERVLVVWNR
                     VQFPDTSTLALGNMGGTDGMGQSGFNDEVNNHYLRIFGNATLLAIIGAGFQLSQPDNNS
                     NNGNNGMTAREQMIAEIGRQWSTVGTEVVRRNLNIQPTLHIRAGYKFNVLVNKDIILPE
                     YQPNH"
                     /name="TrbI/VirB10 family protein"
     gene            12723..13211
                     /locus_tag="RZR84_RS20995"
                     /old_locus_tag="RZR84_20995"
     CDS             12723..13211
                     /locus_tag="RZR84_RS20995"
                     /old_locus_tag="RZR84_20995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_082242801.1"
                     /translation="MASRGVNKVILIGNLGQDPEIRYMPNGGAVANLSLATSETWRDKQ
                     TNEMREKTEWHRVVIFGKLAEIAGEYLKKGSQVYIEGSLQTRKWQDQSGQDRYSTEIVV
                     NIGGSMQMLGGRNGDAPATDQSGQGQTQESPKFSGGDAPAPAKQTNEPPLDFSDDIPF"
                     /name="single-stranded DNA-binding protein"
     gene            13279..13500
                     /locus_tag="RZR84_RS21000"
                     /old_locus_tag="RZR84_21000"
     CDS             13279..13500
                     /locus_tag="RZR84_RS21000"
                     /old_locus_tag="RZR84_21000"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1496 domain-containing protein"
                     /protein_id="WP_082242800.1"
                     /translation="MQIAKLTCLIIFGLSALTATAAESDTENNNQCVYQGQSYGIGSPI
                     NIDGHSYICVKKANKMMWLPAIDAQRYL"
                     /name="DUF1496 domain-containing protein"
     gene            13519..13869
                     /locus_tag="RZR84_RS21005"
                     /old_locus_tag="RZR84_21005"
     CDS             13519..13869
                     /locus_tag="RZR84_RS21005"
                     /old_locus_tag="RZR84_21005"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_088207275.1"
                     /translation="MILFFERSKPLTHKIDNILLSEIKKREPLKYHSFQLTNFISGVLF
                     LCCLCSFVSYIVFSVFLQNSGVEIDPSVTKIFAKVIVGFFLSGFACWFLRTYLYTELEH
                     QIMKIWYRQASS"
                     /name="hypothetical protein"
     gene            14574..14813
                     /locus_tag="RZR84_RS21010"
                     /old_locus_tag="RZR84_21010"
     CDS             14574..14813
                     /locus_tag="RZR84_RS21010"
                     /old_locus_tag="RZR84_21010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726764.1"
                     /translation="MGTLTVRPQPEHEDALAAVGALLQEKRASQTLLKSLMAYEPHCKE
                     IAQLKAALHKAEKERDMYKDKIERFKAAQLALFE"
                     /name="hypothetical protein"
     gene            14870..15127
                     /locus_tag="RZR84_RS21015"
                     /old_locus_tag="RZR84_21015"
     CDS             14870..15127
                     /locus_tag="RZR84_RS21015"
                     /old_locus_tag="RZR84_21015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009047943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_082242798.1"
                     /translation="MLTTFFTSREFNQEIGKAKKAACQGAVFITDRGKATHVLLSIDEY
                     EQISGLNDENIVDALSVPGLSEIDFDTSRLSIFPPDRDIF"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            15127..15555
                     /locus_tag="RZR84_RS21020"
                     /old_locus_tag="RZR84_21020"
     CDS             15127..15555
                     /locus_tag="RZR84_RS21020"
                     /old_locus_tag="RZR84_21020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011251439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family toxin"
                     /protein_id="WP_070133934.1"
                     /translation="MFILDTNVISELRKAGDGKADAQVMRWLSSVNSRQLYLSVITVLE
                     LERGILRVERRDTTQGKMLRRWMDGHVLPLFANRILPVDMAVVRQCARLHVPDPKPESD
                     TLIAATALVHGYIVVTRNTKDFCSTGVNIINPWEDNGN"
                     /name="type II toxin-antitoxin system VapC family toxin"
     gene            complement(15640..15756)
                     /locus_tag="RZR84_RS21025"
                     /old_locus_tag="RZR84_21025"
     CDS             complement(15640..15756)
                     /locus_tag="RZR84_RS21025"
                     /old_locus_tag="RZR84_21025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001584988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="WP_087726763.1"
                     /translation="MDTPLIFSGRQTKEIIGVFAFLAPVKPQNQFPAALWRN"
                     /name="replication protein RepA"
     gene            15867..16757
                     /gene="repA"
                     /locus_tag="RZR84_RS21030"
                     /old_locus_tag="RZR84_21030"
     CDS             15867..16757
                     /gene="repA"
                     /locus_tag="RZR84_RS21030"
                     /old_locus_tag="RZR84_21030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011412247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiator RepA"
                     /protein_id="WP_223364413.1"
                     /translation="MIDSHNQAQEQRSRGIEWRNSYVTNANPVYSAPKECASPPRIITA
                     LRKAALTSNPARHPIWRTADRFHAINHQRLPKERAMNEHRARAVNAICACIADRLNIVT
                     GKVFMTLAQISDSCGLTTYNKDGTPCYSRASRAINEHLEAIGAIHCDRVWDETTGSWIP
                     NLIWVSELFFTLIGYEYGKYEAAQQQQLAWENKGLKEKGEPAISLTEARRRAKVKHIQT
                     AFEVRAKKRAFKTQLRQARKLAAMEKQKAQAKILNDLVKLYSQDELAAMGHVELKRQVE
                     HRYAAMRKLATAPPH"
                     /name="repA"
     gene            complement(17555..17749)
                     /locus_tag="RZR84_RS21035"
                     /old_locus_tag="RZR84_21035"
     CDS             complement(17555..17749)
                     /locus_tag="RZR84_RS21035"
                     /old_locus_tag="RZR84_21035"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726760.1"
                     /translation="MKKFIGKLANFCGGYARLAVIGFVAMFGVIAIIFSLSGAEKIFVV
                     TPIAMMFLFAFLGKYWIEK"
                     /name="hypothetical protein"
     gene            complement(17860..18318)
                     /locus_tag="RZR84_RS21040"
                     /old_locus_tag="RZR84_21040"
     CDS             complement(17860..18318)
                     /locus_tag="RZR84_RS21040"
                     /old_locus_tag="RZR84_21040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223364412.1"
                     /translation="MLEHKFKTVRELKDALNECPDDAEIDISELPNNISRHGLTTVFDG
                     KKVLICEYHDYEIINKYRNIFSELSKTEQSRCGCVYEMYQRNLSTAIDGYLSELTQEDK
                     RKVIQLARAEFDYISPEEITEAIRQNQEDGYCSHGLDPNCCPLGCGDI"
                     /name="hypothetical protein"
     gene            complement(18324..18602)
                     /locus_tag="RZR84_RS21045"
                     /old_locus_tag="RZR84_21045"
     CDS             complement(18324..18602)
                     /locus_tag="RZR84_RS21045"
                     /old_locus_tag="RZR84_21045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012368896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stability/partitioning protein"
                     /protein_id="WP_082242815.1"
                     /translation="MDINKLKKHAPIIEPSESKTVNDFIAQGDKKPTKKAESIMVGFRM
                     DEDTLERLDRLTNGLGKKRINILRASLLAFESLSPSDKAKFLIEIMR"
                     /name="plasmid stability/partitioning protein"
     gene            complement(18664..19326)
                     /locus_tag="RZR84_RS21050"
                     /old_locus_tag="RZR84_21050"
     CDS             complement(18664..19326)
                     /locus_tag="RZR84_RS21050"
                     /old_locus_tag="RZR84_21050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012368895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsA-related P-loop ATPase"
                     /protein_id="WP_036944392.1"
                     /translation="MIIVFGSDKGGVGKTTITANSAVMLQQKTASVALVRTDKNEDLNT
                     WQSLRREQPVPDIPIMTCYGSNTHKEINKLHGVTDVILVDTAGHDSVELRSALLVADVF
                     IAPVSPTSMLEVVTLNKLSSIVNEAKKENTKLKAFALLNRCPTSPFNNDAVKITQYLND
                     DPLLLSPFKTRISNLKAFEKAINEGLGVHELKGKNVGSAKAQLELLFAELIDSVQDS"
                     /name="ArsA-related P-loop ATPase"
     gene            20184..21134
                     /locus_tag="RZR84_RS21055"
                     /old_locus_tag="RZR84_21055"
     CDS             20184..21134
                     /locus_tag="RZR84_RS21055"
                     /old_locus_tag="RZR84_21055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zincin-like metallopeptidase domain-containing
                     protein"
                     /protein_id="WP_082242812.1"
                     /translation="MTMNLHTQTSAPNPAAAASVSPLEQSGSTKTKFSKNKTKTDIYQT
                     VTDSIIEALEMGVKPWVCPWKRNGSVSGIPSNFMTGTAYSGMNIMLLWCSAAKQGFNDS
                     RWLTYKQAQEQGAQVRKGERGTTAIFYKTLEKEAEDGEIEKIPMLKTFTVFNVEQIDGL
                     TLTEEDTAEPVSEFDPLPHVEALFQRTGANITERGQQAFFRPATDEIWLPERHLFTDAA
                     NFYATGLHELVHWTGAKSRLNREKCGRFGSEGYAFEELIAELGSAFLMADLGITGDVQH
                     ESYIASWLKSLRDDKRYIFKAAAAASKAHRYLMEC"
                     /name="zincin-like metallopeptidase domain-containing
                     protein"
     gene            21433..21786
                     /locus_tag="RZR84_RS21060"
                     /old_locus_tag="RZR84_21060"
     CDS             21433..21786
                     /locus_tag="RZR84_RS21060"
                     /old_locus_tag="RZR84_21060"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726759.1"
                     /translation="MTMYQDLPSVLNLINCESPFPCNQASCAQGIADKNSFVEFIVTHK
                     SAGNLHEWNLSYVDRFNRLIKVFYHDHMILHARINMKTGIVNLIAYTVFTDKISSLEAE
                     YLVEQIRQHLDHF"
                     /name="hypothetical protein"
     gene            complement(21832..22413)
                     /locus_tag="RZR84_RS21065"
                     /old_locus_tag="RZR84_21065"
     CDS             complement(21832..22413)
                     /locus_tag="RZR84_RS21065"
                     /old_locus_tag="RZR84_21065"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_087726758.1"
                     /translation="MERTTINFRINDDTLLAQFNHAMAKEQKKYKFATDGIRTIKDLEI
                     IFTASKIKNFRDNEHYLIASLAQKQSPLILNVLNELKDKFEKIYQEERNITGQIIFFKK
                     ILEQVEYHDKTQDINVLISPHVMLFINITALADNIIKQLRVQYLNGSIDETTLLIKRNK
                     ILKQYAALREKLHEMKQERKKLFKKVKDNL"
                     /name="hypothetical protein"
     gene            complement(22413..22865)
                     /locus_tag="RZR84_RS21070"
                     /old_locus_tag="RZR84_21070"
     CDS             complement(22413..22865)
                     /locus_tag="RZR84_RS21070"
                     /old_locus_tag="RZR84_21070"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_082242810.1"
                     /translation="MFRLATPEDYEYLPDIGLYELTFDKRPVQGVRCEDPKQGAADYNN
                     FRKKFKAVIHKEKQRRKNFYQLTEISWNAVFDWAIERGTQEECRLLQAMYHAENNKKYQ
                     QLLLELSKHYGFIKESNLLIPLGLILCNQRIADTEKLIANSVKAGI"
                     /name="hypothetical protein"
     gene            complement(22868..23434)
                     /locus_tag="RZR84_RS21075"
                     /old_locus_tag="RZR84_21075"
     CDS             complement(22868..23434)
                     /locus_tag="RZR84_RS21075"
                     /old_locus_tag="RZR84_21075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012368887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="WP_223364411.1"
                     /translation="MKILIFLVLMIMSNTSFSKSLFIGDSLTYSLASSFSKIEPVDAKF
                     LESTGLKSDNILSWTDYIETMDLSNYDRIYIVLGINDMINENDEILYQDRVDTFIMSLL
                     NKNKNIIWLLPPVLKNAKHESMLLYTRSIIKAACIEHSVDFFDMRDVLGYNFMQTVNDR
                     NIRTDDGIHITPYGADRVITNLLLR"
                     /name="GDSL-type esterase/lipase family protein"
     gene            23533..23763
                     /locus_tag="RZR84_RS21080"
                     /old_locus_tag="RZR84_21080"
     CDS             23533..23763
                     /locus_tag="RZR84_RS21080"
                     /old_locus_tag="RZR84_21080"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_029403597.1"
                     /translation="MENVNKPNNAIEEKIENLKSKLTELDEKREKLITRIDKLESQMNA
                     EKAQKILDDKRQELENLLGKENLDLLFGSKK"
                     /name="hypothetical protein"
     gene            24537..26651
                     /locus_tag="RZR84_RS21085"
                     /old_locus_tag="RZR84_21085"
     CDS             24537..26651
                     /locus_tag="RZR84_RS21085"
                     /old_locus_tag="RZR84_21085"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_087726757.1"
                     /translation="MDQGLYGFRQFGYVIDNFSSVFLYHHWLVLFVIWAIFVLMVSIIV
                     RSLNHVIFIGMSDDDREDSRNVEVNGKRQKRGVFASMQYDKPYFSLLLLRQAGFFIKIL
                     LIFIIAFMTAFFIVTLISAFFDIDYVITPYKAQYYLLTKTNMYGLSIILVGSLVGYIVS
                     AFLYHSFIKPFFGEIDLIFNEEAISRRESSKMRDDKLTDIRNFNFKDSINYNPVDYFHE
                     AKSKKSIFLGIDENNKPILIPKLKWDETNIQVIGKMGSGKGVLSTVALVQCVELYNDIN
                     IIFDPKNDEWAYHVFKHFFKDDLLYIDLNRGQLPQVNPFKGANSDEINELLVASFGLGE
                     KGTDADFYKTGDRKVCRDLSQHFTQGTDLRGLLSIALNENFRKSYDRTGENFFNLLEEL
                     GQLDSISAHDGIDLVDILNNQNKKIIYITGSLRDEVVVKAQKMLFLRMVQILEKRNRNK
                     DVTHVNIMLDEIKYLISKSALEAMGTLRDKKANILFTHQSRGDLEVSTKEIDGQTARKV
                     IEDSAGLRWIYRTDNYESAKWASDFTAGGLVDVERRNLSVNQSNVEMASKEATIFKQKA
                     NYVDISVIQNLPSRCGLIVGDGQLARLAYSSPILVEKSDKCVTSFETQAISSREFLASI
                     RETNDKPKTSSDKKVKNNRNTKPVDNPQSGTMVNRERVNSAVDADRVDSVMAELTMPDD
                     NHGDNYHEHS"
                     /name="MFS transporter"
     Typing          8..822
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="95.0"
                     /evalue="1.16e-174"
ORIGIN
        1 aataatgaat tagttaccta tttcgaggat ggatttcttg gcagaaccaa acggttttat
       61 catctgacag cacaaggtca ggcttttgct gaacaagaac ttggtattac accacggttc
      121 aacggattaa gtcgccgtgc tcatgccccg tcagccctgc tgcatacact ggaaatgcag
      181 aactacacgg cgttgctgat gaaagcaggg gcgaaagtcc gctatctgca tctgccggat
      241 aaaattatgg attactggta cggtggcact gcggcagaag tcgaacgcac gtttaaaagc
      301 caaaaacgtt accgtgatat ttttcggaac tactgtctgc ggatgcgccg taatgacccc
      361 attattaata ccgtgatgta tatcctgcct gattcagcta tgcgggataa agcggcagcc
      421 ctgttttaca gttttgatga actgatgatt gaaggcattc tgactgatgt cagaacgtat
      481 acagggcgtt ttctgtttgc cacccgagcc gaatatgaag cctatctgac ggcgtttccg
      541 caatccggtg tcagagtcga gatgaaactg ccaaatgagg tgtggcaacg ctggcagcga
      601 cacgcagcac aggctcaact gacaccggaa gcgtggttaa ccggtattct taacagggaa
      661 gtgccagttg tgatcaatga gccgatgccg tattcaggtg acggggtgct gattaacctg
      721 actccgacaa aggatgatta caaattctgg ctggcgaatg ctgatgcctg tcataccagc
      781 ctttcagcat ggtgtgcagg gaagcctgtt cacttaaatt tatagaaccg tgcgcagaaa
      841 caggttttga ctgattaccg gcgataatag ttaatcaggt aatcagccaa ttcttcatcg
      901 tcgcaataaa agtaacaggt tgggatctgt aatatagacg ctattttttg cattagctga
      961 taagagggga cactgtagcc gttttcatac tggctgattc gtgaactcgc tgtgctttca
     1021 tctatgcctg cttttatggc cagcagctcc tgtgtgtaat gtcttttttt tctggcggtt
     1081 tttagtcttt cggggatcat ggcaaactcc tttggtgaag tctgccaaaa aaaaaaattt
     1141 aatttattta atgatattaa gatttcttgt ttttcagttt taatgattca ggggggttta
     1201 tcgggcgtga aaaaatctca gcctctttgt accagtattc ttttttttca gggatttctt
     1261 ctctttctgc cttgattaca taggcaattt cttctgttgt gatccccagt aatcttgcga
     1321 ggtgtgcgca ttctgcggga gagacatagc cttttccctg tttccattgt gaaattttta
     1381 tcggtggagc gtccagatat tgggctattt ttcggtaact atcacaaatg gttagctttt
     1441 ttgcttcttc tatgtactca aaaaaatttt ttttcataaa ttattgtctt tggcgttagt
     1501 gtactgtatt ttatatataa tacagtattt tgtaacaatg ttaaccctat actacttttc
     1561 acgcagctta tgggtacgga ttgtgatcac aaacaataca ctgaaacgta agtttttaaa
     1621 tacccttctc tttttcggcg ttttgtccgg ttgcgttatg ctttatcagc attatttcgt
     1681 tgtcaatttt actaaaagta tgccgttagg agtgtacttc aaaagttatc cagcatctta
     1741 tacaaaaaat gatacggttt tggtttgtct cgatgatgag atagcaagat ggtctgttga
     1801 tcatcacatc attgctgatg gtttaggttg ccggcattca gcaccgttac tcaaaaaaat
     1861 cgtagcaact gagggggaca gggtaactgt gacccataaa ggcattgttg ttaatgatgt
     1921 tttagtcccg aatactgcgc caattgccag gaaaattaag cagtggaaca ttatcgatag
     1981 ggaaattcta ttaaaatcaa cggagtatat cgttgtcgcc aatcaaaata atctgtcttt
     2041 tgacagtcgt tattttggtg tagtaacaga ccggaatatt accgcaaaaa tcagaccttt
     2101 ttatttattt gactgatttt taaggtgaaa attttttatc tgtggggctg atagaaccgc
     2161 cttatgcggt agctatcacc tgaataaagg agttctcttg attgatatgc cgagtgtgtc
     2221 tgcatgtgcg ccggagatag ccgcagatac gttacagaaa attattatgg ttgaaagtgg
     2281 cggtaatcct tttgccgtta atgtcaataa actgtccgcc ggaagccagc ctaaaccgaa
     2341 aaacgtggct gatgccgttg cagcgacaca atactggata gcaaaaggct attctgttga
     2401 tgtgggttta atgcaggtaa atagccgcaa ttttaaaatg ttgggtatta ctgatactga
     2461 tttaggctct gtttttgaac cctgcaataa tgtgaagtac ggagcaacaa ttttactttc
     2521 tgcatggaac atgacttcat ccaaagaaca ccagaacgac cggctgatga aatcattgag
     2581 tatttacaat acgggtaatg acgttaacgg atttaaaaat ggttacgtca gtaagtatgt
     2641 gggaagaaac atttccggtt cactggcaaa aacggttgtc actccttata acgcagattc
     2701 cagtgtaggg tttaatgcag actcttttta cggggatgat ttatgaatac gggtgatgat
     2761 aaaaaaatca gtgaccttgc caaaatgctt tggcgggagt tcgatattat tgcgccttat
     2821 ctcagggatg aaaccactat tgaaatcatg ctcaatcctg acggtaaaat atgggttgaa
     2881 cagatcggta agccaatgtt cagtattggc gaaatgtcgt tatataacgc tcaatcatta
     2941 tttgccacca ttgcacacag catggggaaa acaatagata atcgccaccc ttgccttgag
     3001 ggaacgttgc ttattaatga tgcgcgtttt gaggggttct atccccctgt ttcaagtgcg
     3061 cccacctttg ctatccgtaa aaaacctaaa aaaatattct ctcttgatga ttttaaatta
     3121 accgaaaatc agaaatcgac gatggttaca tgggtgaaag aacgtaaaaa tattttagtc
     3181 gtcggcggaa ccagtagcgg taaaacatct ttttctaatg cctttattga cctgatggca
     3241 caatttacac ctgatgatcg tatcgtcatt cttgaaacgc tggacgaaat ccagtgccgc
     3301 gcaaaaaatt attcaaaact gattgaaaca atggatgtga cgatgaatca gttactgcgc
     3361 ggtgtgatgc gttaccgccc tgaccgtatt attgttggtg aagttgttga tgcagcggcg
     3421 ttatctatgc tgaaagcatg gaatacaggg catgacggag ggttatgtac cattcatgcc
     3481 gacagtgccc ttgaggggtt tgaccgcctt tacgatctga ttgaagaaag cgggattaat
     3541 atgtcagaaa gggtgaaccg gctgattgga cgggcgattg acggcgttgt tttcctgaaa
     3601 cgggaacaag gtgttcgggt agtcaaagaa gtcgcaaatg tgacagaatt taacggcagt
     3661 gaatttgtgc ttgattatgt taattaagga aaaactatgt tagagaaata ttactatagc
     3721 cagtcgagac tgacccagca actgatagtg ttaggtgcat tgctactggt ctgtatgttg
     3781 ttaagcagtc atgcaatggc aggtcagacg caaggtttac cttgggaaag tccgcttgat
     3841 aaaatcaaaa acagcataac cggccccgta gcgggagcga tttcctttct cgggatttgc
     3901 gttgcgggaa tgatgctgat ttggggcggt gaaatgtctg atttcaccaa gcgtatcgtt
     3961 tatgtggttc tggttatctc tttaatttta ggggcaagtg tggttatcaa catgtggcag
     4021 ggtaacggtg cattgatccc tctgtctatg gtgtaaacgc catgaaaaca caagagccgc
     4081 tggttagttt tattattcac cgctcgttaa atcgtcctga tttagtcttt gggtgtgaac
     4141 gtaaaccgtt atattgcttg ggcttaattg cagccgttat gattttttct tcttataacc
     4201 tctatattgc gggggcgggt cttgttgttt tctgcgtggg ggtttacctg ttgcgacgta
     4261 tggcgaaagc cgatcctttc atgtcgctga tttttcagcg ggctatccga tatcgttatt
     4321 attaccctgc aaggagcaca ccgtttgcaa ctggtgcaaa attcagaagg aaaaaacaat
     4381 gaagttatat aaaaaacaat acaatacatc actttctttt gctgacttac tgaattttgg
     4441 cgtgatgatt actcccaact taatgttggg taaagatggt tcactgactg ccggattagt
     4501 ttatacctgt tgggattatg aaaattctga taattctgaa ttaaatgacc tggttaatgc
     4561 acttaatgca gcctatctcc ggttgggtac aggtatcaca ttgcatttta cggtaataag
     4621 gagtgaaacc tcagaatatc cgcagccgga aaaaagtcat tttacgtcat tactgaataa
     4681 attaattgat gaagaacgcc ggatcaaatg ggaaagcgca ggggcgcatt tttcgagtgt
     4741 gctttcattt tcaattactt atttacctga aagcatgtca aaaagtcggt taagtgattt
     4801 ctttgttacc gacgaatccg gcactaaaaa atcaaaatca ttaacagata aacacattga
     4861 atactttgaa agcgttattt cagaactcag cggacaatta agcggaacgt ttactctgca
     4921 ccggcttggg gtacgccatg ataacgctac aggtgttgtt tataatgatt tagtccaata
     4981 tttcaatcat tgtatcagtg gtgataatta tccggtcatt catccggata atcagtttct
     5041 tgatgctgtt ttgtctacgg atgattttta tactgagcct cgccttaaaa ttggtaataa
     5101 atatatcagt gtgctttgca ttgatgctta tccggcaagt tcagtgatgg ggatgctgca
     5161 atcgttatca aatttacctt gtgagtatcg ctggacgacc cgcgccatat ttcttgatcc
     5221 gatagatgcg gataagcaaa ttgaaaaata ccgtaaaagt tgggggcaga aagttcgcgg
     5281 atttgtcgat caacttatgg gtaaacacag cgataatatt aattatgatg cagccacgat
     5341 gaaagaggat gcacagattg ctaaaggtga aaataactca aatacggttc gctatctgta
     5401 tcttacgccc acaatagtga ttatggatga agatattgac cgtttggatg aaacgacaaa
     5461 tcttatccgt accacgatta aaaatgtcgt caattttaat gcaagaattg agacagttaa
     5521 tgcaatggat gcctaccttg gcagtctgcc gtctcatacc tatgagaatg tgagacgccc
     5581 ccttttacat accggaaata tgacgcatat agtgccctgt tccacgttgt ggacgggcga
     5641 agaaacatca ccctgcccgt tctttccgcc ggacagtccg ccgctgatga aggtcagtac
     5701 aacgggtaac tccgagttta atcttaattt gcatgaggac gatgtaggac acggcattat
     5761 cggcggtaaa acaggtgcag ggaaatcatc attagtcaca ttaatttctt ctcaatatga
     5821 ccggtatcct gattctcagg tatttacctt tgataaggga cgttctgcaa aagtgttctg
     5881 caaactatcg ggaggaaagt attacgatat tatgacgggc gagcattctc ttaactttgc
     5941 accgctggcg cgtatagatg aaccgagtga gtttatatgg gcgtttgagt ggttacagga
     6001 tattgccgaa attaacggcg taaagctgga ttctgaaaaa gttaaaaaac tgaatgaagc
     6061 cctgaaaatt gtctcaagaa tggataataa ggacggccag taccgcaaca ttgattcact
     6121 gattacaaaa ttgcaagacc gcgaattgaa agatttgttc agtcagtacg gctccggcgg
     6181 ggcatacggt gaagtgctta atcagccaca agaacaaatt acactcagta actttaccgt
     6241 ttttgagtat ggagaattac tggacagggg caataaaatc aaactgccgg tactttttta
     6301 tctctgccac ctgattgagc gacaactcga cggaagaccg acactggtta atattgacga
     6361 ggcatggaag tttttagatg aacctgttgc gggtaaacgc cttttacaat ggctgcgtga
     6421 atggcgtaaa agcaatgctg ccgtggttat ttccacccag aacctgcaca ttatcgaaaa
     6481 agcctttccg ctggtatttt cagaaatcgc tatggcttgc ccgacaaaac tgtttcttag
     6541 taaccccgcc gccgaggaag aagtttcgat caatgcttat aaaattcttg gctgcaaagc
     6601 cgctgaaatc cgcagaatcc gtcatttaac gccgaagcgt gagtattttg tgaaaaaagg
     6661 tgattttcgc cggacattca gcctcgatat ggttgagggt gatatcggac ttgctaccgt
     6721 tgccgcaagc tctaaaaagg atttaaaaga gatagataaa ttagattttg aacattccag
     6781 tgaagaagaa ttactgcacc agtggcttga ttttaaaggt gttgatagtg gctatgtgca
     6841 gtatctgaca gacagactga aatcaagggg tgaaatatga aaaagatatt aattgcaggt
     6901 gtgtttgcaa taagcacatt tacaacgctg aatagctttg cgtggcatgg ggttgctact
     6961 gaaggcacgc aatggctgaa taatcttcaa ctggtaaaac aggttgaaga gcaaatgaga
     7021 accgttaaaa atcaaattca ggatttacaa cgattgccct cagatgttct gaatatggga
     7081 tcaaacaagt taaaggttct tgagacgttt aatgatttaa agcgaattta tcaggaaggg
     7141 caaaatatag cgcaggcagg gcgggacgtt gctaaatatt ataaggatat gggcaatatt
     7201 gatattgccg atgccctgaa aaacgggaat tacccgcagt tattcaatca gtggagccac
     7261 cagaaccacg atacggtaaa aggtattctg gaacagaata aattatcaat ggactggttt
     7321 aatgaccgac agggcgaggt tgcaggatat aacagtatgc tcaattctgc tgatggtaca
     7381 gtcagtgcat tacaggcagc gggtaaaatt gctaatgctc aactggatag tctcagccag
     7441 ttggggcaat tgcagatggc gcaaaataac ctgttagcct ctcaggcggc agttcagcaa
     7501 agcgaaaaag atgcggagag agccgatacg atccggcgtt cagaaatgaa tgtgatcata
     7561 aattctgata acaacaccgc tgctgatttt ctaaagaggg actaaatatg aaactgatta
     7621 ccacaggact ttctttcttc ctgataatta ccgttgtttc tacaggatat ttatggaaac
     7681 aaaataaaga gttgcattat cagattaatg agctatctac cgttgttgct gaacaacgtg
     7741 ttgcagtaca aggttgcctt aaagaaaaaa cagatacgca acatagaggt aaagctaatt
     7801 ttgttattcc agatgattca ggtaatgcgg aagattggtt aaaacgataa ctacgataag
     7861 gatgtgccat gaaaaagatt attttccttt tctgtgtatt gctaatgcca tttttaacac
     7921 atttagcata tgcggatgat gtaagtggat taactggtga atggaagtcg ccggaagaag
     7981 tccgccgtct tattgatgaa agtagaagag aaacagcttt aataaatcag tacactaatg
     8041 agtgtgcaaa gggtaataat caaagttgta ttcaattgga aactataaag tcaaaaaaca
     8101 gcaaaattaa tttagatgca aattttgtca aaacttttag cgattcattt caacaagaaa
     8161 taaaaaagtg gctaccgcct ttgcaaaaag cggccaaata tttacttttt acacttggga
     8221 ttatcgcact ggtcttaaaa atggttccac tggttctaaa gggtgctgat ttaggggaga
     8281 taataaaaga acttataatt tttgttttaa ttattggtat ctggctggca tttataataa
     8341 acgctaaaga gtggactgat gcaatcataa atagctttat gaaactagct caattagcta
     8401 atcaaacatc tatgcaagcc acgcctgttg gaatattaaa acaaggattt attgttgttg
     8461 gaaaggtgtt tactgacccg ataaacccta taacgttatt aactcaagtt atttgtgcgt
     8521 taattataat gatcatttat gcgaaaattg cattttattt gctgaaagtc atgcttgaga
     8581 cgtacattgt ttcttatgga ggcattattc tgttggggtt tggtgggata gctttcacca
     8641 gtgactatgc aaaacgctat tttacctacg ttatatcatg cggcattaaa ttatttatga
     8701 cattactgat tatcggtttt ggcggtaatt ttattgcctc attcctgact ctcaatttta
     8761 ctgaatttgc aaattgcgtc gcaattgttg ctgttgttgt catgcttatg atgctggctg
     8821 aaggaatacc cgacatggca cagtctatgg tcactggtgc cagcttaggc aatagcaata
     8881 tgaatatcgg cggctctctt gcaacaatgg ccgctgccgc cactgcattt accgctgcct
     8941 gttatgccgg agccgccgcc tttaaagcgg caggggcggc caatgcagca ggaggaggcg
     9001 gagccgctac aggtggactt tccggcggtg atttagcgaa tgcgttaagc aaaggcggcg
     9061 gctctggtgt tgccggtggg ggcggttccg gcggcagtag ttcactgcct aacgggggga
     9121 aatccggtgc tcagttagtg aaagagggaa aagtacaatc gcctaataaa aatacgggta
     9181 acacagcaac gggtactgaa tcaggaaaac cacaacaaag cagaacggga gcagccctga
     9241 aagctgtcgc taaatccgtt ggtgagggaa tactcaataa agcggcagga agcagaggct
     9301 ccacggcagc aaacattacc cgtgcagcgt taaatcatgc ggcacaaagt caacagtcca
     9361 cagaaagccc tcgtaaacct attgccagtc cgtatgcaaa aagcaccgga aataatagta
     9421 gcggaaccag taaaatgcct aacaagggaa ataatgatac aggggaaaat caatgagtga
     9481 tgataaattc aaaaaatcgt ccggctggaa cagtttttta ggcaagacta aagaacaagt
     9541 tacgttctac cgatggacga ctatcctttg cgctgtcgcg gctattatct ctatttctgg
     9601 ctgtatttat ttctcttctc aggtgaaata tgtgcccttt gttgttgaag tcaacaaaga
     9661 gtacgcgccg ttgcaggttc atcagctaga atctttaggg caaagcaaag atgcggttac
     9721 acgttcgcaa ctggcaacga ttatcaaaaa tatgcgggta gtctatgccg gagataaaga
     9781 agcgcaatta gatgctatta aatcagtcta ttatttcatc aaaaccaact cgcaacctta
     9841 caaatatgtt caggagatgt tctctgttga tgacccgatg aatcagaaat ttttaaatca
     9901 ggtggaaata aaagccattc ttcctttaag taaagataca tggagggctg aatgggtaga
     9961 aaagaaagct atgcctgatg gtaaaaatgt tctgtcacga aactattcag cggttattca
    10021 ggttgagtat gcagatacta tttctgctga aatgattatc aataacccta tcgggttata
    10081 tcttaaaaat atgcaaatta cagaagaata taaataggat ataacgttat gaaaaaaaca
    10141 attttattta cctcattgct gatttcaggc gttgcattag ctgatcctgt tgtgccttct
    10201 gtcagtaata tagaaaggat taatacaggt gcaacctctc aaccaacaac gccacagcag
    10261 gctatgccat cttcaatgct cttaggtggt aaagacttac ctttaagccg aaaagagcaa
    10321 caggcgatta aaacagcaaa tcaatgggtt aacgggaaac agtatatttc caatggcggt
    10381 caggaggtag tgtacacata cggagcaggt caggcggcca ttattgccac accgctaaaa
    10441 ctcagtgttt ttgagcttga atccggcgaa cgtattgtta atgagggtat tcagttaggt
    10501 gattctgttc gttggcacgc tacccccgta aaacagggga atcagacgaa tgttattata
    10561 aaaccaactg acacaggact atcaacggat ttagttgtcg tcacagaccg ccgtacttat
    10621 cacattaagt taatttcaaa cagtaaaaac tatactccat tagtcaaatt cagttatccg
    10681 gaagatgaaa accaaaaagc gtggaatgcg tactatcaaa attcaggtgc agataatagc
    10741 agtatctcac ttgccggaaa taaaacggga cttgcccctg taaattttga ttataccatt
    10801 aaaggcgata ataaaatgaa accgttgcgg gtttacgaca atggttctca ggtgtttatt
    10861 caaatggatg gaaaactaca ggaaactccc gcattatttg tcattaatgg ctcaggaaaa
    10921 cagcaattag ttaattatcg ttatgtagat aatacctttg ttgttgaccg cttgtttaac
    10981 aaagctgttc tgacacttga tgttggcggt gatcaggaaa aagttaccat cacaaagggg
    11041 taaacgatga aatacaaatt attctttgcc tttgtatgta tggtattagc agggtgtgtt
    11101 agtaagccta atatctcatc gtatgatggt acacagggaa cgatagggaa aaacagcgtt
    11161 caaaaaatgt tatatggcgt tgatgttatt ttttctaaac ttcattcaaa aaatactatt
    11221 ttttatattg aggattcaca ttctgatata gcaaatgctt ttattgaaaa tataaagcga
    11281 aaaggtttta ttgttatcgt tacaaataaa gaagataaaa taaactataa aaaaataaat
    11341 atgggcatga ttgtgaagaa aataacgccg gatatttatt ctctttcaat tattacggat
    11401 aaatacagaa ttaaccaacc ttatgactat caattaaata aaattggtga ggtttccatt
    11461 caaaataaaa ccgaggatgt taatcatggc taacccctca caaaataaaa agctcactaa
    11521 aaaacaaaaa ttattaatga cgataggatt tgctgctgtc ctcattattt ttgttgtttt
    11581 tatttctatt atgagtttag ggactaatac cgatagtcaa acgcaaagtt acgaagatgc
    11641 caaggataaa tcaggtgatc ctgctgaccc atcctatgag gctaatctgt atcgttcccg
    11701 attcagagaa aatactgatt tacaaacacc ccctgcaaca ccagataaag ccccatctgc
    11761 aactggaaca atacaaacag caaatgtgag tcagccgcaa tctaatagca cacagactca
    11821 atcacaggaa cgtgatcaat ttgcggaaaa tgttttaagg atgaagcaac aagcctatat
    11881 ggaggcacta aacagtaaaa caacggtgcg ggttgatgcg ctcagtgata ataacagtcc
    11941 ggagcgtggt agttcagccc cagactatgc ctcaattgca gagcaactcg ccgccgcctc
    12001 gaaagaggga aacggagaat tgtatgccaa catgcagcaa aacaaagaaa aatttgtgaa
    12061 tacagaacgt acctttggct actcaactca gacaagagaa gccgcgttgt ctcagacaga
    12121 aatcaaggcc ggaatgattt taccggcggt acttgttaca gaaatcaatt ctgatttacc
    12181 aggactaatt accgcacaga taaccgaaga tgtgcgtgac agtttgacag gcagaaaaat
    12241 actgatccca agaggttcaa aactcatcgg ctcttatgat tcacaagtag ctatggggca
    12301 agagcgcgtg ttagtcgtct ggaacagagt ccagttccca gacacttcaa cacttgccct
    12361 tggtaatatg gggggaacag atggcatggg gcaatccggc tttaacgatg aggttaacaa
    12421 tcattattta cgcatctttg gaaatgcaac gttacttgcg attattggtg cagggttcca
    12481 gctttctcaa cctgataata atagtaataa cggcaacaat ggtatgacgg caagagagca
    12541 gatgattgct gaaataggta gacagtggtc taccgttggt acagaagttg tgcgccgaaa
    12601 tctgaatatt cagccaacgt tacacatcag agcgggttat aaatttaatg tcttggtaaa
    12661 taaagacatc atattgcctg aataccagcc aaaccattaa cctaggtaat aaggagcaaa
    12721 atatggctag cagaggcgta aataaagtca ttcttattgg taatttaggg caagatcctg
    12781 aaatccgcta tatgcctaat ggtggtgcgg tagcgaatct atcccttgca acatctgaaa
    12841 cgtggcggga caagcaaact aacgagatgc gggaaaaaac cgaatggcat cgggtggtga
    12901 ttttcggcaa actagccgag attgccggag aatacctgaa aaaagggtca caagtgtata
    12961 ttgagggttc tttgcaaacc cgtaaatggc aagatcaaag cggtcaagac cgttattcaa
    13021 cagagattgt tgttaatatc ggcgggtcaa tgcaaatgtt aggggggcga aatggggatg
    13081 ctccagcaac agatcaaagt ggacagggac aaactcaaga atccccaaaa ttcagcggtg
    13141 gcgatgctcc tgcgccagct aaacagacca atgaaccccc acttgatttt tctgatgata
    13201 tcccgttctg aatgatataa agtgattata tatgcaatcc tgagtgtagc ggtagttttt
    13261 aaaacaagag gaataagtat gcaaatagca aaattaacgt gtttgataat atttggcctt
    13321 tctgctctga ctgcaactgc tgctgagtct gatacggaaa ataataatca atgcgtatac
    13381 caagggcagt catacggtat aggctctcct attaacattg atggtcactc atatatctgt
    13441 gtcaaaaaag ccaataaaat gatgtggcta ccggctattg atgcacaacg atatctttaa
    13501 tagggattat tagattatat gattttattt ttcgagcgtt caaagccatt aactcacaaa
    13561 atcgataaca ttcttctttc tgaaataaag aaaagagagc cattgaaata tcatagtttt
    13621 caactgacta attttatttc aggggtgctg tttttgtgtt gtttgtgtag ttttgtttct
    13681 tatattgttt tttctgtttt cttacaaaat tctggtgttg aaatagatcc atctgtaaca
    13741 aaaatatttg ccaaggttat agttgggttt tttttatcag gatttgcttg ttggtttttg
    13801 cgaacatatt tatatactga gcttgaacac cagataatga agatttggta caggcaagcc
    13861 agtagttaaa caattataac caattattta attgggggtt atcaactggc gcaaatagca
    13921 aatctgtaac agataacagc gcgtttaagg gggattagtg gatcataagt tacagcttaa
    13981 agagcttctg ttaatgcaca atttgactca gcgggaagcc gccgcattga tctcttctca
    14041 gtccttgcgt ccctgttctg tcagggctat caagtcgtgg cttaccgatg tatctaaccc
    14101 tagttcgcgt tcgtgtcccg attgggttgt tccactattg aaaatagctc tagaaacaag
    14161 ggattctacg ccagaatcgc cttaacaggg ggctggagtg agtcataata atttaggtta
    14221 ttactaataa ttaagccgtg taaaatctga gggattacct accctaccag cccgattttc
    14281 cctcagattt tgcgtagcga tgcctcaaaa tctgataaag ctacagtttt ccgatttact
    14341 atcactttat ctttctgcag cgcatcgaac tgcggatttt tgctatcact ttttcaatcc
    14401 ggaagcgacc ggccaaacaa aaaatgatag caaaaatagt aaaaggtgat cagctgacca
    14461 aaaatatctg ctatcatttt tgtgttggcc agttcgccgg cgccattcaa aatgatagta
    14521 ttccggcgtg aaagcaagac tggcctcaat gtttagccat ttgaggggta tgtatgggga
    14581 cattaacagt caggccgcag ccggaacatg aagatgctct ggctgctgta ggtgcattgt
    14641 tgcaggaaaa acgagcctca cagacgttgc tcaaatcact gatggcctac gagccacact
    14701 gtaaagagat cgcccaactg aaagccgcac tgcacaaggc cgaaaaagaa cgcgatatgt
    14761 ataaagataa gatcgagcgt tttaaagctg cccagcttgc gttatttgaa taaaacgatt
    14821 agatgtagta acatataaac atagagtgac gaacagaagg aggtgcgcca tgttgacgac
    14881 cttttttacc agcagagaat ttaaccaaga gataggcaag gccaagaaag ccgcttgtca
    14941 gggggctgtg ttcattacgg acagaggtaa ggctacacat gttttgctgt ctattgatga
    15001 gtatgaacag atatcaggac tgaatgatga gaatattgtt gacgcattat ctgtccccgg
    15061 tctgtcagaa attgactttg atacttcgcg gttaagcatt tttccgcctg acagggacat
    15121 tttctgatgt ttatccttga taccaatgtc atttctgaac tacggaaagc cggagacgga
    15181 aaggccgacg cacaagttat gcgttggctt tcatctgtaa attcacgaca actttatctt
    15241 tccgtgatta cggttcttga actggaacgg gggattttgc gcgttgaacg ccgtgatacc
    15301 actcagggga agatgctgcg ccgctggatg gacggccatg ttctgccgct ttttgcaaac
    15361 cgtatcttac cggttgatat ggctgtagtg cgtcagtgtg cccgtctgca cgttcctgat
    15421 cccaagcctg aaagtgatac acttattgca gcaacggctc ttgtgcatgg ctatattgtc
    15481 gttacacgca atacgaaaga tttttgttct acgggggtga atatcatcaa tccgtgggaa
    15541 gataacggaa actgaggatc ttatctcttt taagatcctg aaattgatcc tgatgaaatt
    15601 aagtgttaga tttcggggat aagatttatt aacttctggt tagttgcgcc ataaagcagc
    15661 agggaactgg ttctgaggtt ttaccggagc cagaaaagcg aaaaccccga taatctcttt
    15721 agtttggcga ccggagaaga ttagcggggt atccatcata tactgttaga agatttattg
    15781 ccttctgaca gggagtatag cgacatgcct catctcttgc aagtctcagt atgtgctctt
    15841 tctgcgcaat atatgcgcag aatacagtga tcgatagtca taatcaggca caagaacagc
    15901 gttcacgtgg cattgagtgg cggaatagtt atgtcacaaa tgctaatcct gtgtactccg
    15961 cgcctaaaga atgtgccagt ccgccgcgca ttatcaccgc tttacgtaag gcggctttga
    16021 cgtccaaccc agccagacac cctatatggc gtacagcgga tcgttttcat gccattaatc
    16081 atcaacggtt gcctaaagaa cgtgcaatga atgagcaccg cgcccgtgcg gtaaatgcca
    16141 tttgtgcgtg tattgctgac cgtctcaata tcgttaccgg caaagtgttt atgacactgg
    16201 cgcaaatttc cgacagttgt ggcctgacca cctacaataa ggatggaacg ccctgctaca
    16261 gtcgcgccag tcgcgccatt aacgaacatc ttgaagctat cggcgcaatc cattgtgatc
    16321 gcgtatggga cgaaacaacc ggctcatgga ttcctaacct gatatgggta tcagaactgt
    16381 ttttcacgtt gataggctac gagtacggga aatatgaggc ggcacaacag caacaactgg
    16441 catgggaaaa caagggactg aaagaaaaag gggaaccggc tatttcatta accgaagccc
    16501 gcagacgggc aaaggttaag cacattcaga ccgcatttga agtccgagcc aaaaaacgcg
    16561 cgtttaaaac acagttacga caggccagaa aactggccgc tatggaaaaa cagaaagcgc
    16621 aggctaaaat ccttaacgat ctcgtcaaac tctactcaca ggacgaactg gccgctatgg
    16681 ggcatgttga actgaaaaga caggttgaac atcgctatgc ggccatgaga aaactggcta
    16741 ccgccccgcc acattaaaac attcctgagc aattcaacta tccggccatg tacgccggag
    16801 gctttatcct gcctgatata cttttttgtg taaaaaacat ccactttttt ctgtctgatc
    16861 cgtcatcgac cgtcgttttt cggcatcatg attgtatggc cgcaacatac ccacaattaa
    16921 atgcaaacgt aaataaagga atagatgcaa ccataagaaa tagatgcaaa atcactgtct
    16981 tacttctttt aatcacagaa aaagaaataa taacgtgcta acgcactgtt aataacgccc
    17041 gcccttgcag cggccaaaag gccgcgccgg ttcggttagt cgctccgctc ctgagttagc
    17101 acccgcaagc gggcaaattg ctgaacattt ctttcgtctc cgaccatccg gcaatctcac
    17161 cgctttaaat tccgtgtaat tggttcgctt cgctcacagt ctggcaggaa aaggggctga
    17221 cttacgcttc acaccgcatc aaaaacgtca cgtaagccac atagacgact ttttttaaag
    17281 aaattcatag aacgggaagg actaaaaaat agaattgcgt acagcagcac tgaggaggat
    17341 tttaaacata gaacttaaaa aacccgtaac gctcgccgca ggacgtggcc gagcgtagcg
    17401 agttaacgac cgaggaagcg gaatttcacc gatgcgacag aaagcactta cacaccgtag
    17461 caacgttcag cctaccgcct ctcaccgttc gttgctcaac agcgaccccg acgacaaaaa
    17521 ccagttttgc gcgtctctcg ctgttaggtg gcagttactt ttctatccaa tatttgccca
    17581 aaaaagcaaa caggaacatc atcgctatcg gagtcaccac aaatattttt tcggctcctg
    17641 agagtgaaaa aatgatagca ataaccccga acattgccac aaatccgatc actgccaatc
    17701 tcgcgtaacc accacaaaaa ttagcaagtt ttccaatgaa ttttttcaat atagccccct
    17761 tgcaattaac gaaaaagtta aagtgataaa tctattaaaa ttgaaattga aattgaaatt
    17821 atcatccaaa cgatagcggt gacaaaattg ttttgggggt taaatatcac cacaacctaa
    17881 agggcagcaa ttaggatcta aaccgtgtga acaataacca tcttcttgat tttgtcgaat
    17941 agcttcggtt atttcctctg gtgatatata atcaaattca gctcttgcca attggattac
    18001 ttttctttta tcctcttgag ttaattcact taaataacca tcaattgctg tgctcaagtt
    18061 gcgttggtac atttcataga cacacccgca acgagattgt tctgtttttg ataactcact
    18121 gaatatatta cgatatttgt taattatttc ataatcgtga tattcacaaa ttaagacttt
    18181 tttaccatca aaaaccgtgg ttaaaccgtg tcttgatatg ttattaggta gctcgcttat
    18241 atcaatttcg gcatcatcag ggcattcatt aagcgcatct ttaagttctc taactgtttt
    18301 gaatttatgt tcaagcattg tagttacctc attatctcta ttaaaaactt agccttatcg
    18361 ctaggtgata gtgattcaaa ggcaagcagc gaagcccgta aaatgttaat acgtttcttc
    18421 cctagtccgt tagtcagccg gtctaaacgt tctaacgtat cttcatccat acgaaaacct
    18481 accatgatag attctgcttt ttttgtcggc tttttatccc cttgggcgat aaaatcatta
    18541 accgtcttgc tttctgacgg ttcaattatt ggcgcgtgtt tttttaattt atttatatcc
    18601 ataatccacc tcaatgcaaa gctaatcatt gattaatcaa tgattttcaa ttgttttgtt
    18661 ttcttagcta tcctgaacag aatcaatgag ttcagcgaat aaaagctcta attgtgcttt
    18721 ggctgatcct acatttttac ctttaagctc atgtactccc aacccctcat ttatggcttt
    18781 ttcaaaagcc tttaagtttg atatacgggt tttgaatggg gatagaagca ggggatcatc
    18841 gttaagatat tgtgtgattt ttactgcatc attattaaat ggtgaagtag ggcagcgatt
    18901 aagtaaagca aaggctttta gctttgtgtt ttccttttta gcttcgttca caatggatga
    18961 taatttattc aatgtgacaa cttctaacat agatgttggg cttacaggag ctataaatac
    19021 atctgcaaca agtaatgcac tacgaagctc gacgctatca tgtccggcag tgtctaccaa
    19081 tattacatcc gtaacgccgt gcaatttgtt aatctcttta tgtgtattgc ttccgtaaca
    19141 agtcataatt gggatatcag gaacaggctg ttctcgtcgt aaactttgcc atgtgttcaa
    19201 atcttcgttt ttgtctgttc gcactaatgc tacagacgcc gttttttgtt gcaacattac
    19261 tgctgagtta gccgtaattg tggtttttcc tactccacct ttatctgagc caaaaactat
    19321 aatcattttc cttacctctc agtgagattc atcaaggatt aatcaatggc tatcaataat
    19381 gattaatcgt tagatatcaa atggtgataa tctatgatta atcatatcaa gataatcata
    19441 gattatcaat aatgattaat caaaagacag caatataagt taatctttga ttaattattt
    19501 gcgtaattca acttatcaag cgttgggcga aaaaaagcga tgaagtttaa ttttgttaaa
    19561 atgtttctta attgtttcta ttttaacaaa aaacaaacaa tggtattttg actggatttc
    19621 tgacagaaga gttcctgttt tagcgggtag ggcggttgtg tgacagggta acagtgattt
    19681 ttggtgctaa agtcctgaat ttaacataat gactcttacg cgcccctcgt ttgtagcacc
    19741 aatattaaaa tgtcactccg gtgcggcgtt ttactaaatg gccgtggcgg ggcagacaca
    19801 aacacacccc cacggttgaa agaaacccgc cccgccagac acaacatata gtatgtctgt
    19861 cagctgcgac cggtacaaca tatagcgtta tccacagaaa cggtggataa gtcgataggc
    19921 tactgattaa caacaaaatc aaaagcaagg tcaaaaccat tccgccacta cagcgtaagg
    19981 ggcgctaagt ccgtgtgtgc tggccgtcat tttctcctgt gttgcctttc ccctccgtat
    20041 caggcttccg gtaatcgttc cccgttacaa cctgttccgc aagggtatat aaacgctccg
    20101 cgcccttgca gaccagaacg ataacggggc gtcgaaccgt caggcgatac gaagacgaaa
    20161 ttcacactga cggagaaaca accatgacta tgaatctgca cacccagaca agcgccccta
    20221 accccgcagc ggcggccagc gtatccccgc tggagcagtc aggctccaca aaaacgaaat
    20281 tttctaaaaa caaaaccaaa acagatattt atcagacagt gacagacagc attatagaag
    20341 cccttgaaat gggggttaaa ccgtgggtgt gtccgtggaa gcgtaacggt tcggtgtctg
    20401 gtattccttc aaattttatg actggtacag cctacagcgg catgaatatc atgctgttat
    20461 ggtgcagtgc ggcaaagcag ggatttaatg attcccgctg gctgacctac aagcaggctc
    20521 aggagcaggg cgcacaggtg cgtaaagggg agcgcggaac gacagccatt ttttacaaga
    20581 cgttagaaaa agaagctgaa gacggcgaga tagaaaaaat tccgatgctg aaaacgttca
    20641 ctgtatttaa tgttgagcag atcgacgggc tgacactcac agaagaagac accgccgagc
    20701 cggtaagcga gtttgatccg ctgccgcatg ttgaagcact ttttcagcgc accggcgcga
    20761 acatcaccga gcgcggccag caagcctttt tccgtccggc tacagatgaa atctggttgc
    20821 cggagcgtca tttattcacc gatgccgcca acttttacgc tacggggctt catgagcttg
    20881 ttcactggac aggggcaaaa agccgtttaa accgtgaaaa atgcggacgg ttcggatcgg
    20941 aagggtacgc atttgaagaa ctgatcgcag agcttggaag tgcttttctg atggccgatt
    21001 taggcattac cggcgacgtt cagcatgaga gctatatcgc ttcctggtta aagtcattgc
    21061 gtgatgataa acgttacatc ttcaaagcgg cggcggcagc ttcaaaagcg caccgctatt
    21121 taatggagtg ctgattaggt tcagaccccg cgaatcgcgg ggtttgtaaa acgtcataag
    21181 gatgtcaaaa tcccacataa aaggatgtgg gatttttcct ttttttaccg tagaactccg
    21241 tcaatattga gtcgcctttt actgtttttt tgtctgattt ttatgctaaa gtaattaatg
    21301 cctgtcacgg tgcagacaga ctacggtctg tacaggctta aatgcactac atccaatcat
    21361 ttttgttgaa gcaacgtcac gttatgttgc ttcggcaacg tagcgtgact tctgcttaaa
    21421 ggagttaacg ttatgactat gtatcaggat ctgccctctg tactgaatct gattaactgt
    21481 gaatcaccat ttccatgtaa tcaggcttct tgtgctcagg gtatcgcgga caaaaactcg
    21541 tttgtcgaat ttattgttac gcataaatca gcaggtaatt tgcatgaatg gaatttgtct
    21601 tacgttgaca ggttcaatcg tttgattaag gttttttacc acgatcacat gatattacat
    21661 gcacgtatta acatgaaaac aggtattgtc aatctcattg cctataccgt gtttactgat
    21721 aagataagtt cgcttgaagc agaatatctt gtcgaacaaa tacgccaaca cttagatcat
    21781 ttctaactga ttaagtgcat gaaagggaaa gctaatgctt tccctttatt tttataagtt
    21841 atctttcact tttttaaaca attttttcct ttcctgcttc atttcatgca atttttcacg
    21901 taaagcggca tattgtttca gtattttatt tctttttatc agtaaggtgg tttcatctat
    21961 agagccattc aaatactgga ctcttaattg tttaatgata ttgtcagcca acgctgtaat
    22021 attaataaac aacataacgt gaggtgaaat taatacatta atatcttgtg ttttatcgtg
    22081 atattcaact tgttctaata tctttttgaa aaagattatt tgacctgtga tgtttctttc
    22141 ttcctgatag attttttcaa atttatcttt taattcattc aatacattga gtattaaagg
    22201 ggattgtttt tgtgccagtg acgctatgag gtaatgttcg ttatctctga aatttttaat
    22261 ttttgaggca gtgaaaataa tttctaaatc ttttatagtt cttatcccgt cagtggcgaa
    22321 tttatatttt ttctgttctt tagccattgc gtgattaaat tgcgctagta gcgtatcatc
    22381 attaattctg aaattaattg ttgtccgttc catcagatac ctgccttaac gctgttagca
    22441 attaattttt ctgtatctgc gatccgttgg ttgcaaagta tcaatcccaa tggaatgagt
    22501 aaatttgatt ctttgataaa cccgtagtgt ttgcttaatt caaggagtag ttgctgatat
    22561 tttttgttat tttcggcatg atacattgcc tgtaataaac gacattcttc ctgtgttccc
    22621 cgctcaatcg cccaatcaaa aacggcattc caagaaatct cagtgagctg ataaaaattt
    22681 ttccggcgtt gtttttcttt gtgaataact gccttgaatt tttttctgaa attattgtaa
    22741 tctgcggctc cctgttttgg atcttcacat cgaacgccct gcaccggacg tttatcaaac
    22801 gtcagttcat ataatccgat atccggtaaa tattcgtaat cctctggtgt ggctaatctg
    22861 aacatattca cctcaatagc aagttagtga tcaccctgtc tgcaccatac ggggtaatgt
    22921 gaatgccatc atctgttctg atgtttctgt cattcactgt ctgcataaag ttataaccca
    22981 gtacatcacg catatcaaaa aaatctacac tgtgctcaat acatgcagct ttgatgattg
    23041 accttgtgta aagcaacata gactcatgct ttgcgttttt aagtaccgga ggaagtaacc
    23101 agataatatt tttattttta tttaatagtg acattataaa ggtatctaca cggtcttgat
    23161 aaagtatttc atcattttcg tttatcatat cattgatacc taacacaata tatattctgt
    23221 catagttgct taaatccatt gtttctatgt agtcagtcca gctaagaatg ttatcggatt
    23281 tcagtcctgt gctttctaaa aatttcgcat ctacaggttc gatttttgaa aaacttgatg
    23341 ccagactgta agtcagagaa tcaccgataa aaagtgattt tgagaatgat gtgtttgaca
    23401 taatcatcaa aactaaaaaa atcaatatct tcattattgt attgcctttt ttttgtgatt
    23461 gatgttagat agccatcttt gcacttactg ataagtaagt attaaacctg ccggaaaatc
    23521 aataggtgat gtatggaaaa tgtgaacaaa ccaaataatg ctattgaaga aaagatagaa
    23581 aacttaaaaa gtaaactcac tgaactagac gaaaaacgag aaaagttaat cacaagaatt
    23641 gataaacttg agtcacagat gaacgctgaa aaagcacaaa aaattctcga tgataagaga
    23701 caggagcttg agaatttact cggaaaggaa aatttagatc tgctttttgg cagtaaaaag
    23761 tagcaaaaaa aaagagcctg taaaggctct ttttttgcgt gtaaatagct gattgcttgt
    23821 tggtctactt gttgactcac ttgttgtttt gctgtcaaca aatgagtcaa caagctaaaa
    23881 atgtgcggat atacatagat ccgcatgaca gggatagata gttaatctat ccctgtcaac
    23941 tgcattgatt tatcattctg ataaatcaac aaaaatgttg ccgttaccgg caatgagggt
    24001 aatgacctcc tgaacgtcgg tcaaaaccct caaggtcaaa agaggcgcac accgtcagtc
    24061 gttccacgac tgaccacccc caaaaagacg ccgtttttaa cggctcattt tcggtactgc
    24121 cgaaaattca ccgaaaactg gcttttttga gggtggtcag tcgcgcggaa ttttgcgata
    24181 aagccgcaaa atatccttac tcgtgacggt gtgcgggggc gctgcccccc aaaaaggtcg
    24241 cgctaggtcg cgctcaattg cgtgggcgca attacccttt ttggctcccc ccgaaaccgt
    24301 catcatcgtc gcttttggcg cgacggctga tgatgagttc gacgacacaa gccgctatac
    24361 acacagcggc aagttgtctc actcattttt tttcttagca attttttcaa aattgaagaa
    24421 aaaaaaccga acatcaagtt ccgtgtcgtt gtccagattg tgctcagttt ttgttgattt
    24481 aatcgatccc ttaacttaca tttattctat tgtaatctga tggcgcaggg tgaattatgg
    24541 atcaggggct ttatggattc aggcagtttg gttatgtgat tgataacttt tcatctgtat
    24601 ttttgtatca tcactggtta gtgctttttg tcatttgggc tatctttgtt ttgatggtca
    24661 gtatcattgt cagaagttta aatcatgtta ttttcatcgg aatgtctgat gatgacagag
    24721 aagattcaag gaatgtagag gttaatggta agcgtcaaaa acgtggcgtg tttgcatcta
    24781 tgcaatatga caaaccttac ttttcgttat tgcttttaag gcaggcaggt ttttttatta
    24841 aaatactgct gatttttatt atagctttta tgactgcatt ttttattgtt actctgattt
    24901 ctgctttttt tgatattgat tatgtgatta caccttacaa agcacaatat tatcttttaa
    24961 ctaaaactaa tatgtatgga ttgtcaatta ttttagttgg ttcgcttgtt ggttatattg
    25021 ttagtgcatt cttataccat tcatttatta aaccgttttt cggagagata gatttaatct
    25081 ttaatgaaga agcgatttca cggcgcgaat catcaaaaat gagagatgat aaactaaccg
    25141 atattcgaaa ttttaatttt aaagacagta ttaattataa tcctgttgat tactttcatg
    25201 aggctaaaag taaaaaaagt attttcctgg ggatcgacga aaacaacaag ccaatattaa
    25261 tccctaagtt aaaatgggat gaaacaaata ttcaggtgat tggtaaaatg gggagtggta
    25321 agggggttct ttctaccgtt gcgcttgttc agtgtgtgga gttatataac gatattaata
    25381 ttatttttga ccctaaaaat gatgagtggg cataccatgt atttaagcat ttctttaaag
    25441 atgatttact ctatattgat ttaaatcggg ggcagttgcc acaggttaat ccatttaaag
    25501 gggctaattc tgatgaaatt aacgaattgt tagttgccag ttttggattg ggtgaaaaag
    25561 gaactgatgc agatttctac aagactggtg acagaaaggt atgccgtgat ttatcacagc
    25621 attttacgca aggtacagat ttgcgcggac tgttaagcat cgctttaaat gaaaatttcc
    25681 gaaaatcata tgaccggacg ggcgaaaact tttttaatct tcttgaagaa ttgggacaat
    25741 tagattctat cagtgctcat gatggcattg atttagtcga tatactgaat aaccaaaata
    25801 aaaagattat ctatatcaca ggttcgctgc gtgatgaggt tgttgttaag gcacaaaaaa
    25861 tgctcttttt acggatggtg caaatccttg aaaaaagaaa cagaaataaa gatgttactc
    25921 acgtaaatat tatgcttgat gaaattaagt atcttatttc caaaagtgct cttgaagcaa
    25981 tggggacgct cagagataag aaggccaata ttctttttac ccatcaatcc agaggtgatt
    26041 tagaggtttc caccaaagaa attgacgggc aaactgcaag gaaagtgatt gaagatagtg
    26101 cagggctacg ctggatttac cggacagata attatgagag tgcaaaatgg gcgagtgatt
    26161 ttacagcggg tggtctggta gatgtagagc gtcgtaatct ttctgttaat cagtctaatg
    26221 ttgaaatggc ttcaaaagaa gcgacaatat ttaagcagaa agctaattat gttgatattt
    26281 cagttattca aaatcttccg tcacgttgcg ggttaatagt gggggacgga caactggcta
    26341 ggctggcgta cagcagtccg atccttgtcg aaaaaagtga taaatgcgtt acttcatttg
    26401 aaacacaagc gatttcttcc cgtgagtttt tagccagtat cagagaaaca aatgataaac
    26461 cgaaaacttc aagcgataaa aaagtgaaaa ataacagaaa tacaaaacct gttgataatc
    26521 cgcaatccgg cacgatggtt aaccgtgaac gagtaaacag tgctgtagat gcggataggg
    26581 tagattctgt tatggctgaa ttaaccatgc cagatgataa tcacggagat aattatcatg
    26641 agcatagctg attacggttc attgagtaat caaaagcgac tggaacaacg ccaatttaat
    26701 caacataaga tattaagttt tttggcgcag gaacgcagcg ttactattga cagtctgagc
    26761 cgtttgtttg atttttccgc aaaccaaaaa atctatttat tacttaagaa cctgata
//
