LOCUS       NZ_CP151150            24818 bp    DNA     circular CON 16-APR-2024
DEFINITION  Staphylococcus aureus strain BSN152 plasmid pSa14640, complete
            sequence.
ACCESSION   NZ_CP151150
VERSION     NZ_CP151150.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38637731
            Assembly: GCF_038096285.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 24818)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN152 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24818)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN152
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly :: CP030326, CP048645, CP053009, KT780704,
            CP053637, CP014405
            Genome Coverage                   :: 174.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_038096285.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 22:59:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,988
            CDSs (total)                      :: 2,906
            Genes (coding)                    :: 2,817
            CDSs (with protein)               :: 2,817
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 47 of 89
            Pseudo Genes (incomplete)         :: 41 of 89
            Pseudo Genes (internal stop)      :: 32 of 89
            Pseudo Genes (multiple problems)  :: 29 of 89
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP151150.1.
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University, Detroit MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24818
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN152"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pSa14640"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2021-11-03"
                     /collected_by="Andrew D. Berti"
     gene            complement(join(24499..24818,1..46))
                     /locus_tag="UXR25_RS14785"
                     /old_locus_tag="UXR25_14790"
     CDS             complement(join(24499..24818,1..46))
                     /locus_tag="UXR25_RS14785"
                     /old_locus_tag="UXR25_14790"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="WP_001550107.1"
                     /translation="MFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYKIKSILKHGEK
                     NYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGGQEPESRMIEP
                     ISLGFYEQNWYLIGFAG"
                     /name="WYL domain-containing protein"
     gene            complement(528..1322)
                     /gene="aph(3')-IIIa"
                     /locus_tag="UXR25_RS14790"
                     /old_locus_tag="UXR25_14795"
     ARG             complement(532..1322)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(1415..1945)
                     /gene="sat4"
                     /locus_tag="UXR25_RS14795"
                     /old_locus_tag="UXR25_14800"
     ARG             complement(1419..1945)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(1942..>2577)
                     /locus_tag="UXR25_RS14800"
                     /old_locus_tag="UXR25_14805"
                     /pseudo=""
     CDS             complement(1942..>2577)
                     /locus_tag="UXR25_RS14800"
                     /old_locus_tag="UXR25_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(2718..3392)
                     /locus_tag="UXR25_RS14805"
                     /old_locus_tag="UXR25_14810"
     CDS             complement(2718..3392)
                     /locus_tag="UXR25_RS14805"
                     /old_locus_tag="UXR25_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(<3449..3625)
                     /locus_tag="UXR25_RS14810"
                     /old_locus_tag="UXR25_14815"
                     /pseudo=""
     CDS             complement(<3449..3625)
                     /locus_tag="UXR25_RS14810"
                     /old_locus_tag="UXR25_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(3639..4376)
                     /locus_tag="UXR25_RS14815"
                     /old_locus_tag="UXR25_14820"
     CDS             complement(3639..4376)
                     /locus_tag="UXR25_RS14815"
                     /old_locus_tag="UXR25_14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(4369..5298)
                     /locus_tag="UXR25_RS14820"
                     /old_locus_tag="UXR25_14825"
     CDS             complement(4369..5298)
                     /locus_tag="UXR25_RS14820"
                     /old_locus_tag="UXR25_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(5414..>6052)
                     /locus_tag="UXR25_RS14825"
                     /old_locus_tag="UXR25_14830"
                     /pseudo=""
     CDS             complement(5414..>6052)
                     /locus_tag="UXR25_RS14825"
                     /old_locus_tag="UXR25_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002501357.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            complement(6115..6789)
                     /locus_tag="UXR25_RS14830"
                     /old_locus_tag="UXR25_14835"
     CDS             complement(6115..6789)
                     /locus_tag="UXR25_RS14830"
                     /old_locus_tag="UXR25_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            7263..8729
                     /gene="msr(A)"
                     /locus_tag="UXR25_RS14835"
                     /old_locus_tag="UXR25_14840"
     ARG             7264..8726
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8828..9727
                     /locus_tag="UXR25_RS14840"
                     /old_locus_tag="UXR25_14845"
     CDS             8828..9727
                     /locus_tag="UXR25_RS14840"
                     /old_locus_tag="UXR25_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(10196..10939)
                     /locus_tag="UXR25_RS14845"
                     /old_locus_tag="UXR25_14850"
     CDS             complement(10196..10939)
                     /locus_tag="UXR25_RS14845"
                     /old_locus_tag="UXR25_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            11365..12348
                     /locus_tag="UXR25_RS14850"
                     /old_locus_tag="UXR25_14855"
     CDS             11365..12348
                     /locus_tag="UXR25_RS14850"
                     /old_locus_tag="UXR25_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <12368..12657
                     /locus_tag="UXR25_RS14855"
                     /old_locus_tag="UXR25_14860"
                     /pseudo=""
     CDS             <12368..12657
                     /locus_tag="UXR25_RS14855"
                     /old_locus_tag="UXR25_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            13204..13353
                     /locus_tag="UXR25_RS14860"
                     /old_locus_tag="UXR25_14865"
     CDS             13204..13353
                     /locus_tag="UXR25_RS14860"
                     /old_locus_tag="UXR25_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(13521..14213)
                     /locus_tag="UXR25_RS14865"
                     /old_locus_tag="UXR25_14870"
     CDS             complement(13521..14213)
                     /locus_tag="UXR25_RS14865"
                     /old_locus_tag="UXR25_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            14323..14517
                     /locus_tag="UXR25_RS14870"
                     /old_locus_tag="UXR25_14875"
     CDS             14323..14517
                     /locus_tag="UXR25_RS14870"
                     /old_locus_tag="UXR25_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            15633..16250
                     /gene="cadD"
                     /locus_tag="UXR25_RS14875"
                     /old_locus_tag="UXR25_14880"
     ARG             15634..16247
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16269..16616
                     /locus_tag="UXR25_RS14880"
                     /old_locus_tag="UXR25_14885"
     CDS             16269..16616
                     /locus_tag="UXR25_RS14880"
                     /old_locus_tag="UXR25_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            16773..16865
                     /locus_tag="UXR25_RS14885"
                     /old_locus_tag="UXR25_14890"
     CDS             16773..16865
                     /locus_tag="UXR25_RS14885"
                     /old_locus_tag="UXR25_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(17037..18008)
                     /locus_tag="UXR25_RS14890"
                     /old_locus_tag="UXR25_14895"
     CDS             complement(17037..18008)
                     /locus_tag="UXR25_RS14890"
                     /old_locus_tag="UXR25_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            18132..18551
                     /locus_tag="UXR25_RS14895"
                     /old_locus_tag="UXR25_14900"
     CDS             18132..18551
                     /locus_tag="UXR25_RS14895"
                     /old_locus_tag="UXR25_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(19065..19910)
                     /gene="blaZ"
                     /locus_tag="UXR25_RS14900"
                     /old_locus_tag="UXR25_14905"
     ARG             complement(19069..19910)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.29"
                     /coverage="100.0"
     gene            20017..21774
                     /gene="blaR1"
                     /locus_tag="UXR25_RS14905"
                     /old_locus_tag="UXR25_14910"
     ARG             20018..21771
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.8"
                     /coverage="100.0"
     gene            21764..22144
                     /gene="blaI"
                     /locus_tag="UXR25_RS14910"
                     /old_locus_tag="UXR25_14915"
     ARG             21765..22141
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            22408..22986
                     /locus_tag="UXR25_RS14915"
                     /old_locus_tag="UXR25_14920"
     CDS             22408..22986
                     /locus_tag="UXR25_RS14915"
                     /old_locus_tag="UXR25_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(23209..23394)
                     /locus_tag="UXR25_RS14920"
                     /old_locus_tag="UXR25_14925"
     CDS             complement(23209..23394)
                     /locus_tag="UXR25_RS14920"
                     /old_locus_tag="UXR25_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            23656..24330
                     /locus_tag="UXR25_RS14925"
                     /old_locus_tag="UXR25_14930"
     CDS             23656..24330
                     /locus_tag="UXR25_RS14925"
                     /old_locus_tag="UXR25_14930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     ARG             8829..9724
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7264..8729
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             8829..9727
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(1416..1933)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(2240..2541)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(19066..19910)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="95.37"
                     /coverage="100.0"
     Typing          12714..12861
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(10197..10939)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          11366..12348
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12480..12649
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 atttccctgc tgtaatcaat gcacccactt ccgccgctgt aaacattacc ggcggaagta
       61 ggaagccctc tacaagaaaa tatccttttc cggcctcaga tccaattggt attccggctt
      121 cttcaagtgt ccggatatct ctgtaaactg tccttaagct tatattaaat cgctgtgcaa
      181 tttctttggc aggaattatt tttttgattg cagctgaata agaatagagg ttactctgtt
      241 aatcctgttc aaattttatt cctcctctgt gacttccata aaaagtatat cctatgcgtt
      301 cttaagctag ctgctgttag tgcttctcat tgcaccctgg ttataaaagc catactcaca
      361 aacctcttca ccaaaactct ttacatctct aatatagaac tctatctagc gaacttttag
      421 aaaagatata aaacatcaga gtatggacag ttgcggatgt acttcagaaa agattagatg
      481 tctaaaaagc ttgtagttaa agctttttag acatctaaat ctaggtacta aaacaattca
      541 tccagtaaaa tataatattt tattttctcc caatcaggct tgatccccag taagtcaaaa
      601 aatagctcga catactgttc ttccccgata tcctccctga tcgaccggac gcagaaggca
      661 atgtcatacc acttgtccgc cctgccgctt ctcccaagat caataaagcc acttactttg
      721 ccatctttca caaagatgtt gctgtctccc aggtcgccgt gggaaaagac aagttcctct
      781 tcgggctttt ccgtctttaa aaaatcatac agctcgcgcg gatctttaaa tggagtgtct
      841 tcttcccagt tttcgcaatc cacatcggcc agatcgttat tcagtaagta atccaattcg
      901 gctaagcggc tgtctaagct attcgtatag ggacaatccg atatgtcgat ggagtgaaag
      961 agcctgatgc actccgcata cagctcgata atcttttcag ggctttgttc atcttcatac
     1021 tcttccgagc aaaggacgcc atcggcctca ctcatgagca gattgctcca gccatcatgc
     1081 cgttcaaagt gcaggacctt tggaacaggc agctttcctt ccagccatag catcatgtcc
     1141 ttttcccgtt ccacatcata ggtggtccct ttataccggc tgtccgtcat ttttaaatat
     1201 aggttttcat tttctcccac cagcttatat accttagcag gagacattcc ttccgtatct
     1261 tttacgcagc ggtatttttc gatcagtttt ttcaattccg gtgatattct cattttagcc
     1321 atttattatt tccttcctct tttctacagt atttaaagat accccaagaa gctaattata
     1381 acaagacgaa ctccaattca ctgttccttg cattctaaaa ccttaaatac cagaaaacag
     1441 ctttttcaaa gttggcgtat aacatagtat cgacggagcc gattttgaaa ccacaattat
     1501 gatagaattt acaagctata aggttattgt cctgggtttc aagcattagt ccatgcaagt
     1561 ttttatgctt tgcccattct atagatatat tgataagcgc gctgcctatg ccttgccccc
     1621 tgaaatcctt acatacggcg atatcttcta tataagcgta ccggttccaa ttttttcgca
     1681 gtttaacttt tccgacgcat ttatcgtctt ggtagtaaag atatattatc ttatcagtat
     1741 tgtcaatata ttcaaggcaa tctgcctcct catcctcttc atcctcttcg tcttggtagc
     1801 tttttaaata tggcgcttca tagagtaatt ctgtaaaggt ccaattctcg ttttcatacc
     1861 tcggtataat cttacctatc acctcaaatg gttcgctggg tttatcgata tctttcaggt
     1921 gccctgcttt catttctgta atcactgttc ccgcctctct tctatatcag cggcatatgt
     1981 gctatccagg cagccggttt taccagtgta ttttttatac atgtccctgg tatattttgt
     2041 tatattccta tcatactccg gataggcata atgaagcctt tccgccacct caccggatac
     2101 cgccctgaac aattgatggc atagaaataa tgcttcccat atgttttcat aggaatccat
     2161 ccggtaggtg gacaaaagtt tctcccacaa atcctcggat atataccttt caataaactt
     2221 atagttcttg cctacacttc atttaaagcc tgtttcgatg ccgaccttcc atgatatcat
     2281 tctcagcagc tcatggcgaa caatctgatt aaaatgatca atagcaaata aaatttcctt
     2341 acggcacaat cctttaataa cataaggtgt tacattccaa aattcattgc agcaatcatc
     2401 atactccctt gcgcttggct ttcttacatg ataatctata tcagtcggaa ctatgtccct
     2461 tttaattcta caatctttat caattagaac ctttattaat ttatcgccct ttaggtaatt
     2521 atctaactct tccaagggca ataaggtaag atcaatttta ttgtaatcat caaatagcta
     2581 taatagattt agaggtaaag aaattaaata cattgaagag cagaaagatt ttacaaaaga
     2641 gtattttaat aaaaatgatg gttctgttgc aaagtaaaaa atatagctaa tcactaatat
     2701 atcatgtcag tgttcgttta acttgctagc atgatgctaa tttcgtggca tggggaaaat
     2761 ccgtagatct gaagagacct acggttcttt ttatatagag cgtaaataca ttcaatacct
     2821 tttaaagtat tctttgccgt attgatactt tgatatcttg tctttcttac tttaatatga
     2881 cggtgatctt gctcaatgag gttattcaga tatttcgatg tacaatgaca gtcaggttta
     2941 agtttaaaag ctttaattat tttagccatt gctgccttcg ttgaaggtgc ctgatctgta
     3001 actacctttt gaggcttacc aaattgttta atgagacgtt tgataaacgc atatgctgaa
     3061 tgattatctc gttgcttacg caaccaaata tctaatgtat gtccctctgt atcaatggca
     3121 cgatataaat agctccattt tccttttatt ttgatatacg tctcatcaat acgccatttg
     3181 taataagctt ttttatgctt tttcttccaa atttgatata aaattggggc atattcttga
     3241 acccaacggt agatcgttga atgatgaacg tttacaccac gttctcttaa tatttcagat
     3301 atatcacgat agctcaatgc atatcttaga tagtagccaa cggctacagt gataacatcc
     3361 ttgttaaatt gtttatatct gaaatagttc atacagaaga ctcctttttg ttaaaattat
     3421 attataaatt caactttgca acagaacctc ctaactgtat taccacctta aaagtagttg
     3481 cagacgcact tcctaaatcg tcagcagtgt ttaaccacat atcatcaaca ataatcatat
     3541 gacctgttga tgatactgga gcaaattctg tcaacccttc aactacacct aaaataaatg
     3601 ctttaatctg ctctataaaa cccatttttc tcctcctttt aacttatatc agttttttta
     3661 aagtatgaga ataatataat tacactgaat atagatgtaa caattatgat aattaaagat
     3721 aatagaaatg gataagtatt aggtaatgtt cctctagata tgtctccaac tgcagcccaa
     3781 ggaaataatc ctctatgttc agaattagca gtcattaaat ttatcaaagt aattattatg
     3841 gttaaaacaa ttgtgggaac ataattttta aaatatatcg acaaaataat tattggtgga
     3901 gataatatcc ataataacac tccgccaata acaaatgtaa agaatgaatc aattattaaa
     3961 ctctggctta acccttgaaa atgcaatagc atacctagca ttaaagttag caaccatgca
     4021 ataacagata gtgtttgaat ccacaagaat aataatatta ttttacttac taaaaaactt
     4081 tctctagata taggtataat taataagttt tttaaagtat cttctatata ttctcttcca
     4141 aacaaatagg ctattataac cccatataga ggaggtccaa taattagcat atgatataaa
     4201 ctgacttctt caaataactg tttaaataca atattaggag tcggtacttt cgtccgcata
     4261 ctaataaaag aagctacaac caccataaaa ggtgctacgc atgtacctaa aatacttatt
     4321 agaaacatat atgatctttt taacttaata aattctgtac ggagtagatt atccaattgt
     4381 gccacctcct actaagtctt cgaaataagt ttctagatta tcttctatca ctctcatctg
     4441 gaaaacatca atattgttta atactaataa tctattaatt tcttgttgtc tatcaatatg
     4501 tgaataaatt ttaaattcgc cattttcttt aattttatag tcataaattc cgaagttagt
     4561 ttccaacaaa catgcaactt tttcttcatc tgatactgat atacttataa attgtctgtt
     4621 cttttttttt aaatcttcat acataatttc ttctaacaaa actccgttat gaataatacc
     4681 caccttgtct actaactgct ctatttctga caatatatga cttgaaatta aaatggttat
     4741 atttctagat tgagccagat ccttaatcaa ctttctaatt tcttttatgc caataggatc
     4801 taatccattc gtcggctcat caagtatcaa taattcggga ttgtgcaata aagctctcgc
     4861 aatccctaaa cgttgcttca tacctaaaga ataattttta aacaatttta ctttttcaga
     4921 agctagtcct actatttcta acacttcttc aattgcattt tctttttgta tacctaatat
     4981 tttagcattt atagttaagt tctctttagc tgtcaaatta ctataaaaac ctggcgtttc
     5041 aaccatagca ccaatatttt ttaaaatttc agttttatta ctttcgaact ctttttcaaa
     5101 tattttaata ttacctttcg taggtttaat taagcctaaa agcattctta tagtagttgt
     5161 tttgcctgca ccatttcttc ctaaaaaacc ataaatttgt ccactttcaa cagttatact
     5221 caaattatta actgctatct gacttccata ttgctttgtt aagttattta tttcaattat
     5281 attattcaaa tttttcacct ctggcacctt tcttagtttg ttgttacctt tatcttacgc
     5341 gcgattagaa aaggctgcct ttatctattc ttacaaaaac agccgctaat cttacaaaaa
     5401 tgaaagattg gagttattta aattgaatgg tgaatattga accatcgttt aatgtagatg
     5461 tagcacttac tttatggcct aagcgctttg agattgtgct gacaatatat aaaccaatac
     5521 cgcttgattt ctcacttatt ctaccgttat agcccgagaa acctttatca aagattttcg
     5581 gtaaatcact cgcattaatg ccgataccgt tatctcggat tgataatttc tttgtatttt
     5641 cgtcaaacgt aatccacaca tctttgccac gtgcatattt taatgcattg tttaatattt
     5701 gctcaatcat aattgatgcc catttggcat ctgttaatat aaccgcttca cttttctcat
     5761 aatgcaactt tgtttgatga tgaataaact gtatcgcata acgtttaatc agtggtcgaa
     5821 ttaattcatc tacactcact tccataaaga ccatgtatgt cttttggttc atgagtttca
     5881 aatagttcag tgcaagattc gtgtaattat caatttgtaa gacttcatta cgcacgttag
     5941 aaatcacgtg ttcatcagga tcttcaagca gtaactttga tgctgtaatc ggtgtcttga
     6001 tttgatgcac ccacattaaa aaatatgact ctaactcact ttggtagtta ataaagggtt
     6061 ctgttgcaaa gtaaaaaata tagctaatca ctaatatatc atgtcagtgt tcgtttaact
     6121 tgctagcatg atgctaattt cgtggcatgg ggaaaatccg tagatctgaa gagacctacg
     6181 gttcttttta tatagagcgt aaatacattc aatacctttt aaagtattct ttgccgtatt
     6241 gatactttga tatcttgtct ttcttacttt aatatgacgg tgatcttgct caatgaggtt
     6301 attcagatat ttcgatgtac aatgacagtc aggtttaagt ttaaaagctt taattatttt
     6361 agccattgct gccttcgttg aaggtgcctg atctgtaact accttttgag gcttaccaaa
     6421 ttgtttaatg agacgtttga taaacgcata tgctgaatga ttatctcgtt gcttacgcaa
     6481 ccaaatatct aatgtatgtc cctctgtatc aatggcacga tataaatagc tccattttcc
     6541 ttttattttg atatacgtct catcaatacg ccatttgtaa taagcttttt tatgcttttt
     6601 cttccaaatt tgatataaaa ttggggcata ttcttgaacc caacggtaga tcgttgaatg
     6661 atgaacgttt acaccacgtt ctcttaatat ttcagatata tcacgatagc tcaatgcata
     6721 tcttagatag tagccaacgg ctacagtgat aacatccttg ttaaattgtt tatatctgaa
     6781 atagttcata cagaagactc ctttttgtta aaattatatt ataaattcaa ctttgcaaca
     6841 gaaccgtatt ttatgagtac actctaaatt aaggagatgt ataatcaatc taaaattgta
     6901 tttttatact tttgttatat aatctttcta cttagagata tattgtaaaa aaaccaacaa
     6961 aatgttatat taacattact attttatcga tgaaggagga ttaaaatgac agcttctatg
     7021 agactcaaat aaaccttttt gaatacaaaa ctaaattaat tcaaaaaggc ttgtccgcaa
     7081 tacacactca taggatgact tatgtcattt tttatccttc gataggaata ataaacgctt
     7141 tcaaatacta aaacatcata ataaattttt aagtgtttga aagtgtaatg tgaatgagac
     7201 gggagtagcc tgtctcattt ttttgcgtac acgtccttta aatatacaag gagtgtataa
     7261 atatggaaca atatacaatt aaatttaacc aaatcaatca taaattgaca gatttacgat
     7321 cacttaacat cggtcatctt tacgcttacc aatttgaaaa aatagcactt attgggggta
     7381 atggtactgg caaaaccaca ttactaaata tgattgctca aaaaacaaaa ccagaatctg
     7441 gaacagttga aacggttggc gaaattcaat attttgaaca gcttaacatg gatgtggaaa
     7501 atgattttaa cacgttagac ggtagtttaa tgagtgaact ccatatacct atgcatacaa
     7561 ccgacagtat gagtggtggt gaaaaagcaa aatataaatt agctaatgtc atatcaaatt
     7621 atagtccgat attactttta gatgaaccta caaatcactt ggataaaatt ggtaaagatt
     7681 atctgaaaaa tattttaaaa tattactatg gtactttaat tatagtaagt catgatagag
     7741 cacttataga ccaaattgct gacacaattt gggatataca agaagatggc acaataagag
     7801 tgtttaaagg taattacaca cagtatcaaa atcaatatga acaagaacag ttagaacaac
     7861 aacgtcaata tgaacagtat ataagtgaaa aacaaagatt gtcccaagcc agtaaagcta
     7921 aacgaaatca agcgcaacaa atggcacaag catcatcaaa acaaaaaaac aaaagtatag
     7981 caccagatcg tttaagtgca tcaaaacaaa aaggcacggt tgagaaggct gctcaaaaac
     8041 aagctaagca tattgaaaaa agaatggaac atttggaaga agttgaaaaa ccacaaagtt
     8101 atcatgaatt caatttccca caaaataaaa tttatgatat ccataataat tatccaatca
     8161 ttgcacaaaa tctaacattg gttaaaggaa gtcaaaaact gctaacacaa gtacgattcc
     8221 aaataccata tggcaaaaat atagcgctcg taggtgcaaa tggtgtaggt aagacaactt
     8281 tacttgaagc tatttaccac caaatagagg gaattgattg ttctcctaaa gtgcaaatgg
     8341 catactatcg tcaacttgct tatgaagaca tgcgtgacgt ttcattattg caatatttaa
     8401 tggatgaaac ggattcatca gaatcattca gtagagctat tttaaataac ttgggtttaa
     8461 atgaagcact tgatcgttct tgtaatgttt tgagtggtgg ggaaagaacg aaattatcgt
     8521 tagcagtatt attttcaacg aaagcgaata tgttaatttt ggatgaacca actaattttt
     8581 tagatattaa aacattagaa gcattagaaa tgtttatgaa taaatatcct ggaatcattt
     8641 tgtttacatc acatgataca aggtttgtta aacatgtatc agataaaaaa tgggaattaa
     8701 caggacaatc tcttcatgat ataacttaaa aactatacac taatttatat tgaatattag
     8761 gttcatttat atcaatataa aaaatacgtt cacaagaaaa atataataga aataaggatc
     8821 caataaaatg actcgacata atgaaattat taaatgtgca gaaaaatatc aattacacat
     8881 ccaacctcaa acaatctcat tgaatgaatc gggacttgat tttcaagttg catttggaaa
     8941 agataaacat ggagtagaat gggttttgag actaccaaga agacctgacg tttataaacg
     9001 aacaaaaccc gaaaaacaaa cggtagactt cttacagaag aatgtttcat ttgaaatacc
     9061 gaagtggaaa gtacatgcaa aagaccttat tgcttaccca aaacttacag gtaaacccgc
     9121 agccacaata gatccagaaa tacaaaatta tgtatgggaa attgaacaca aaccattacc
     9181 agaaaacttt attaacacat tagctgaaac actcgtagat ttacacaaca taccagaaga
     9241 aaacattaac gttcagcata taaatatcaa aaccatacaa gaaataaaaa atgactttca
     9301 aagaagaatg aataaagtta aagaaactta tggcgtatca gatgaattat ggaacagatg
     9361 gaaacaatgg ttagaaaacg acgaactatg gcctcgacat gcgaccatga tacatgggga
     9421 cttacatcca ggacatataa tggtagataa ccaagcaaac gtcacaggtc tcatagactg
     9481 gactgaagca acccactccg acccatcaat ggactttata ggacaccatc gtgtattcga
     9541 cgacgaagga ttagagcaac ttataacagc atacggtaaa gctggaggtg aaatatggcc
     9601 acgaatgaaa gagcatataa tagaactcaa tgcagtattc ccaatgttta tcgctgagtt
     9661 tgctatggaa tcaggagaat cggcgtatga aacgatggca ttgaaagagt taggtatgaa
     9721 agagtagaac ttatattaaa agaggcccat tttaaagacg aaggcaatcc tgatgaaatt
     9781 ttaaaactgc gtttaattag tgatggtctt tggttttcta taatgtatta aatatctgga
     9841 catggaacaa atgcaacaaa tggaaagaat cgttttcgaa atttctaact ccttaaatca
     9901 ggaggataaa taaacggtca ttttcattga aagcacttat ataaatttca tcaattttaa
     9961 tacctaccgt aaatacattt cataagtatt aaacagatga ttaaaatttt tagttaattt
    10021 aaatatttat gatagagatg accttcaaat gaacgtttat aacgcaatca tgatgagagt
    10081 attaatacag ttaattattt gaaatacttt agtttacata atcgatgatt accagaagtt
    10141 ctcactatat aaaagacact aaaattttat aacttttagt gcctaatcaa ttattttagc
    10201 taccaaacaa acgactccaa aacccctttt taggttccgt ttcttcactc ttttcttcta
    10261 tatcactatc attgtcattt agattagctg gaacgtcttc tttttttgct tcttcacctt
    10321 gtgtactttc gtcgctttga cttccagata tatccttata ttgaatctct gtttctttag
    10381 tttcttcctg atctctgtta atatttacag gattagtagt atatgttttt tcttgtgcat
    10441 caacgttttg tctagtgtta gtagatgtat caaagggata attaaggtgt ttttcttttt
    10501 ctaattgatt ttctaatttt tgaatctttt tattactctc taatgccaga acttgctgat
    10561 tttcaagcaa ttttgatctt tcttgcaact cttttctgta aaattcaatt gttgtttcat
    10621 gacgactttc ttgtttttca atttgattat ttaaagtatc aatctgattt ttaaggattt
    10681 ctactatttg agcatcgctt ttcgattcaa aattaatatt atccgaccct tttttttgtt
    10741 tgtcttcagt agtactttca aaaccatatt tctttttatt ttcatttact ctttgaatga
    10801 ttttttctat atcggtatct tctttaataa acgaagtgtt ttcctgtttt attgtctcta
    10861 tattcaatcg cttaatatta ttaaaaatcg tttgcttact aacccctaat tcttcactca
    10921 actttttcac acttttcata tcatcaaccc tttataaaat gtttataaac ccttgataaa
    10981 atattataag cttataatgc ttaataataa agtgattaat aaataaaaat aaacatccat
    11041 caaccttttt atcaagggtt tatgaaaggt ttatgatatt tatcaagggt ttataaaccc
    11101 ttgataaagc tatattttcc cttttataag tttatttaaa gtgctataat aaacttaata
    11161 taacaaaaac cccaactact ggtaatagtc ggggtttggt aataaaacgt ttagaaactg
    11221 tttatttata taattttcga tacttgtatt atataatgaa taatatctta gtgcaagcac
    11281 ctaaatcatt aaataaatgt aaagctaaat aaaaacgttt tattacctct taccaaacta
    11341 aaatatggaa agaggttttt tgtcatgcaa aatcaatatt ttacagtgca agaaaattac
    11401 aaagaaagat tttatcaaat ccctaaagta ttctttacca gtgaaaatta taaaaatcta
    11461 actaatgata tgaaaatagc ctatgctatc ttacgtgatc gcttaaattt atctattaaa
    11521 aatagctggg ttgatgaaga tggtaacatt tactttgttt attcaaatga aaagctaatg
    11581 gaaatcttaa attgtaaaaa agaaaagtta acaaaaataa aaaaagggtt agaaaacgat
    11641 ggtctactca ttcaaaaacg acgtggttta aataaaccaa atattctata tttaatgaaa
    11701 cctattgtca cagaacgtga tatttacaaa atagaaaaag aagaaaacga tgttgaacct
    11761 tacggcgaga aggaagttcg aaaatcgaac gtccagaagt tcgaaaatcg aacgtccaga
    11821 agttcgaaaa tcgaacgtcc agaagttcga aaatcgaaca ctaatgatac tgactttaat
    11881 gacattgact ttaatgatac tgagaataat gatatgaatg acttgaatga tataaagtac
    11941 aaaaatgaaa ttagtaatca ttcaaatcat tcaaatcaat ttacacataa ttttgatgat
    12001 aaagaaatgc tattgcaaga attcccagaa caactaacta attatttatt aaaatatgat
    12061 tatagagatt tagaaatcat aaaggctgtt attcttaaag caaaaaaatc atttaattca
    12121 aggcatgaag atatgcatta catgttagag gacattgagg atgaaatatt aacttcttta
    12181 aaaagactta aaaaagctat acatgatagg ggagttaaag gccaaaagga aacaatcaag
    12241 tcaatgcaag cttatttaat gcaaacaatt ctaactgaac ttgaagaaac acatgccctt
    12301 tatatgcgcc gtaaaaacat gaaacaatat aatatcttta atcaataatt caaatgattt
    12361 tataacactc gaagagacat caaaatattc cgttaaatca tctgactttt taactgatga
    12421 cgacgaaaaa aatcaagaaa ttgtaagtga tttagaaaaa ggtttgtatc gaaaacgtat
    12481 gttaagttat ggtggattgc ttaaacaaaa gcataaaatt ttaaacttag acgatgccga
    12541 agatggtaat ttgattaata caagtgatga agataaaacg acagacgaag aaaaaaagca
    12601 cattcaatta ccgcaatttg gaatttcgaa aagcaaaatt attatttaag acattagtga
    12661 taactgatgt ctttttttat tgtttttctg taaaaaagtg ctgtcttatt tttgtgacaa
    12721 atgctgtatg tagtgtcaca aaagtgtgac actacagctt tgtatgatat cactttaaaa
    12781 taacttaaaa cccttggaat gtctggcctt gccagatcta tcatttttga atgatagcaa
    12841 atttccctta tgctcttacg gagattttag agttaaatta aaatttctaa gtttttgata
    12901 agaaaagccc tgcaggaatt tagaaaaaca tggggaagtt ttaaagtatt ttatgctaat
    12961 ttttaaattt gcatgtaaat gggcagtatc taaaaaatta gtcactgatt ttgctgaaat
    13021 ttttgtttgt gaaattagca tatatttatt tggctcatat ttgcgtttta agagactgta
    13081 tagattttta agtacaaaac ctatatgatt tgcctctaag tcttcaaaat gcctcttaaa
    13141 atccaaaata aaagtgttta atattgtaat aaggattgct atttttataa aaggagagat
    13201 atcatgaaga ttaaaacttt cgctactttt actcatcgtc aattagataa acaagttaat
    13261 aggtttttaa agaatgatat tcatgtatta gaaattcaaa cacacagtaa ttggttatat
    13321 atttcagcta ttgtttttta tgaggataaa taaggaacat cgtatttatg ccgaaaaaat
    13381 ttattgatgt tgagaagaac ccttaactaa acttgcagac gaatgtcggc atagcgtgag
    13441 ctattaagcc gaccattcga caagttttgg gattgttaag ggttccgagg ctcaacgtca
    13501 ataaaacaat tggaataaaa tcaacctaca gagcatccag ctgcaaatgc agttccgcaa
    13561 actgcttcac atacaccgcc ggctattgga tttacgattg cccatactcc acagtagtga
    13621 gcacatgcat aaagtccagc catactacaa gcgaatgctt tgccgttcca tttgaatcct
    13681 gcatatgtta ccggtctgtt tttatcaact ttttcagcct tatattcaac gtaatttttg
    13741 ttaataagta tttttccctc tttgttttca gtcatacttc ttttttcggc aatgaatttt
    13801 gtgatttttt tgttgtagtt atcatatatt gtttcagaaa ctacaatttc ttttgttttt
    13861 tcatttttat aagcgttatt agctatgtag ccatatgcat ttttatcatt tgcttctgta
    13921 gctagatatt ttaatttaga atttttgtct tctagcttta tttttttaaa tccttctttt
    13981 ttcatttgct tttcgaattt ttgcatatct tcatttttat tttgcaattg ttctagaaaa
    14041 cttatttctt tcttggtcat ttgtgatact tcgatgtttt tgcttttcaa tttttctttt
    14101 tgattttcta gtaaagaact tttttgttct tcatttgcgt aagcattaga aaaattcgcg
    14161 ctaaatacca gtaggaacaa ggaaattatt gaaaataatt ttataatttt catttgatac
    14221 ctccaagata ataagatatt ttaattgtat aagtaagcgc tttataaaat caatatttat
    14281 tttaatatat ttataaacat atttttgaaa ggagtctatt ttatgaatga aaatttagaa
    14341 aaatatataa aaagtttgcc acttttaggt ttgttaatta gtattttgtt aattgtttta
    14401 ttctttttta ttttagatgt tgatgaagat ttattcgtgg tttttttata ctgtttattg
    14461 cctttgatag ttaatttgtc tatttatggt ttttatgttt ttgttaaaag aaagtaagat
    14521 tatgaataat tttgttttta atttgtatgc tttgaggggg ttggaaaacg gtaggtgtat
    14581 agattagatt tcttgttttt ttgaaacgag tgtgaacgag tttcttcttg tcttgatttt
    14641 tgataaaaac gccctacagg aatttagaaa aacgtgggga agttttaaag aattttatgc
    14701 taatttttaa tttgcatgta aatgggcagt gtctaaaaat agttattgtt tttgctcaaa
    14761 tttttgtttt tgaaaatagc atatatttat ttggctcata tttgcgtttt aaaagcatat
    14821 ataagtttta gatataaaac tatatgaatc acccctaaat ctttaaaatg ccctcttaaa
    14881 attcaaaata agggcataaa aaataaaagc taccccagat aaagtgaggt agctttttct
    14941 ttcatacggt ctatttattt ttctttcgac gccgtatcgt cgatgtaatt caaaaaagtt
    15001 atgggctata aatctacatc actttttcaa gaatgtagta gcaatattca acgcaaatta
    15061 atttttataa ctgctcggaa tatctcaagc cgtttcttta attttgaaat aaaaaaatcg
    15121 acgaaggtcg attacgtttt tgcacatgtc gatttatccg acgtataagt gcgcccttac
    15181 gggatttaac tagattataa cgacgaattt tagacctgta aagcaataac aattaggtct
    15241 accaggtaga taaagtgtac aaaatagaac cgaaaaagtt atttattttg aagatttttc
    15301 gtagatataa tttgctaata aacttcctaa aactgaataa agaaaaatag ttaaactcat
    15361 gtaatcactc cataattctg aagtgtctcc atgtctacgc atagacacgc atttatgccg
    15421 aaaaaattta ttgatgttga gaagaaccct taactaaact tgcagacgaa tgtcggcata
    15481 gcgtgagcta ttaagccgac cattcgacaa gttttgggat tgttaagggt tccgaggctc
    15541 aacgtcaata aagcaattgg aataaagcac ctatgattat ttaaaaatat aagttataat
    15601 acattcaaaa atatttttga atgaggtgta ttatgattca aacggttgtt gctgctgctg
    15661 ttctttatat tgctacagca gttgatttat tagtaatttt attaatattt tttgctagag
    15721 caaagactag aaaagaatat agagatattt atgttggtca atatttaggg tctattattt
    15781 taatattagt tagtttgttt ttagcttttg tattaaatta tgttccagaa aagtggatat
    15841 taggtttatt gggtttaata ccaatttatc ttggaattaa agtggctatt tatgatgatt
    15901 gtgaaggaga aaagagagct aaaaaagaat tgaatgaaaa aggattgtct aaattagttg
    15961 gtacggttgc aattgttacg atagcaagtt gtggcgccga taatattggt ttatttgttc
    16021 cgtattttgt gacattaagt gttactaatt tattacttac tctgtttgtc tttttaattt
    16081 taattttctt cttggtgttt actgcacaaa aattagctaa tattccagga attggagaaa
    16141 ttgttgagaa atttagtcgt tggattatgg ctattattta tatagcttta ggtttattta
    16201 ttattattga aaatgacact attcaaacaa ttttaggatt tatattttaa tttagggtgt
    16261 gattttatat gagttatgaa aatacttgtg atgtgatctg tgtacatgag gataaagtta
    16321 acaatgcttt aagtttttta gaagatgata aatctaagaa attacttaac attttagaaa
    16381 aaatttgtga tgagaagaaa ttgaaaatca tattatcttt gattaaagaa gatgagttgt
    16441 gtgtttgtga tatttctttg atattgaaaa tgagtgttgc ttcaacttca catcatttaa
    16501 ggcttttata taaaaatgag gtacttgatt tttataaaga tggaaagatg gcatattatt
    16561 ttattaaaga cgatgaaata agagagtttt tctctaaaaa tcatgagggt ttttgaaacg
    16621 agtttcttct tgtcttgata ctataaaaaa caaagttata taacataaga cgacttatcg
    16681 gaagtagata tgcttgtata ttcacagatg gtataataat agagtcgcct atctctcagg
    16741 cgtcaattga cgaagagagg aggtgcatta ctttgctaat cattttcgtt cacatcatag
    16801 caccagtcat cagtggctgt gctgttgcgt attatactta ttggcttagt aaacgcaaca
    16861 aataattaat aggcgacttt ataagccagc atcgaaaaaa tccccacact actgcaatag
    16921 tgtggggatt ggtgcattaa ttgttaatca ttttcgttat ataaattata acactggtta
    16981 gtagagaaat gcaaaatgat tgaattaata gtaaatgtat taatgaatac tcacacttat
    17041 acttttaaaa tagttcttcc taaatgttgt ccttttaaaa gctgatctat cgttttatag
    17101 aattcttcaa atccaatttc attgtataga agtgaatttc ctatattcca ttcatttgct
    17161 aacttactcc atatatcttc acggatatta tgatcaacat atacagaatc aatgccaatt
    17221 aatttaatac ctctaagaat aaacggtaat atattagcgt taagtgaatt tcctgctaca
    17281 tttccacata cagtagcaac accttgataa tttagacgtt ttaaaccgta taatgttaca
    17341 ttactcccca ctgtatctaa gaaataatca aaaatacctt ttttaagcgg tttattatca
    17401 tcttcaatta ttattacttg ttttgcacct aatttttttg cgatttctat ttgcttttct
    17461 tttcttacga tagcagtgat attttcatat ccaattttat gtaaaatttg tatagcaaca
    17521 ctgcccacac cacctgtagc cccagacact aaaatttcag gttgtgattt gatattcatt
    17581 ccatattttt ctagttcaaa aattgataat gctgccgtaa aaccggctgt gccatatacc
    17641 atagactctt taatagacat ttcttgggga ataggaacaa tccactctcc aggcacttgt
    17701 gcatattctg aaaatccacc tgtatgtgtc acgccaacat cataaccagt aactaataca
    17761 ttatcgcctt ctttaaactt atcattcgaa cttgattcaa caatacctgc aaaatctata
    17821 ccaggaatca taggataatc tctaattaca ccgcctttat attgtaaagc tagcatatcc
    17881 ttataattta ttgaagagta taccactttt actaatacat cacccttcga taaatgagat
    17941 tcatcaactt tttctacttt ataactaaca tttgatgcac tttttctcac tactaccgca
    18001 ttgaacattt attagccttc tttcacaatt gttttgtaga agtatgtttt tgttgcaaaa
    18061 ctattttcct acaaaactta tcatgatatg ataagcgagt caatactaat gatttaagag
    18121 aggttttagt tgtggaatta gataattgta taaattattt gttgagtact tctcagaata
    18181 gagtttttaa acattttaaa agtttattaa gtccctataa tattactcca gcagaatatg
    18241 gtgttttgaa ttgcttgatt aatagtaatt tgaatacacc taaagcgatt ggtaatactt
    18301 taaatttaga accttcaaca atatctggaa tattagataa gatgtccaaa aaggatctaa
    18361 taacacgtca aactgataat gaaaatagaa gaactgtgct aataaacagt acaaataaag
    18421 caaaagactt atggccaaca ttagaaaaga aagcctatca acttaataat cattacttcg
    18481 ctaatttaac taatgaagaa actgtagtgt ttaaaaagat attactaaag ataaataaaa
    18541 ctacgtttta atttttacgt tataaaaaag ttgaagtgcg aattataatc gagtaaatat
    18601 aaatgatagc ttagcttaat tatatattaa agccaactat acttttattc ccgaaaaacc
    18661 tactatccaa atttctaaga tactttagcc tctataataa acatattgta atataattta
    18721 tgtattattt aggtttaccc taatcgaaca ataaaaaata cttgtaaaat gctattgtca
    18781 ctttgcttga tatatgagaa ttatttaacc ttataaatga gaaaaaagca acgcacttta
    18841 aataagatac gttgcttttt cgattgatga atacctataa ttaaactatt catctattat
    18901 ttatgatttt ttgtatatac aatatttcta gtttgttaaa gagaattaag aaaataaata
    18961 tcgaaaataa tagagggaaa atcagttttt gatatcaaaa ttatacatgt caacgataat
    19021 acaaactata agatgatatc agtatttatt atgcatttag aatattaaaa ttccttcatt
    19081 acactcttgg cggtttcact tatcaactta tcatttggct tatcactttt attgtcttta
    19141 ttcgtaaaaa tgactaaaac aataggttca gattggccct taggataaac aaaagcaaca
    19201 tcatttctag aagcatatgt tattgcttga ccacttttat cagcaacctt acagtctttt
    19261 gaaacaccgt ctttaattaa agtatctccg cttttattat ttaacattaa atcaagtaag
    19321 aattttttgt tttctttgct taattttcca tttgcgataa gtttatttaa agtcttaccg
    19381 aaagcagcag gtgttgaagt atcttttttg ctctttggtg aataataatt taattctatc
    19441 tcatatctaa ctggatttgt tactttatct cctagtcctt ttagacgttg tttaactttt
    19501 ttgatcccac cgatctcttt tataatttta ttgtttgctg tattatcact atatgccatt
    19561 gaagcctcaa taagttcttt taaagtgata tcttttccta catatttttc taaaatagga
    19621 gaataagcaa ctatatcatc tttgttaata tgtatttttt tatttaactt attataaggt
    19681 acttgttcta acaaaatagc actatttatc gcttttgaag tcgaagcata ggcaaatctc
    19741 ttatctgaat taaattttac ttccttacca cttttagtat ctaaagcata aacaccaata
    19801 tgagcattat attttttttc taaatcattt aactctttgg catgtgaact gtttgaatta
    19861 catgcactta aaactaaagc aattacaatt aaaaatatta actttttcaa aataaaccct
    19921 ccgatattac agttgtaatt tttataaatc aataatatta caattgtaat attgatgtca
    19981 attgtttatt ataaatattt gaaagaaggt gtcaaaatgg ctaaattact aataatgagc
    20041 gtagtaagct tttgttttat atttctattg ttagtatttt ttaggtacat attaaaacgc
    20101 tattttaatt atagtttaaa ttataaagtt tggtatctaa ctatgcttgc tggattaatt
    20161 ccttttatcc caattaaatt ctcttttata aaatttaata atgtgaataa tcaagcgccc
    20221 acagttgaaa gtaagtcaca cgatttgaac cataacataa ataccaccaa acctattcaa
    20281 gagttcacaa cagatatcca taagtttaat tgggattcaa ttgataatat ctgcacagtt
    20341 atttggatag ttttagttat tattttaagt tttaaatttt tgaaagcctt attatatctt
    20401 aaatatttaa agaaacagtc actttatcta aacgaaaatg aaaaaaataa aatagatacg
    20461 atacttttca accatcaata taaaaaaaat attgtgattc gaaaagcaga ggctattcaa
    20521 tctccaataa ctttttggta tgggaaatat attattttga ttcctagttc atattttaaa
    20581 agtgtaattg ataaaagact aaaatatata atactgcatg aatatgctca tgctaaaaat
    20641 agagatactt tacatttaat tatctttaat atcttctcta ttgttatgag ttacaatcca
    20701 ttaatacata ttgtaaaaag aaagataatt catgacaatg aagtagaagc tgatagattt
    20761 gttcttaata atattaacaa aaatgaattt aaaacttatg cggaatctat tatggactcc
    20821 gtattaaata ttccattttt taataaaaat atattaagcc attcatttaa tggtaaaaag
    20881 tcattactca aaagaagatt aattaatata aaagaagcca atttgaaaaa acagtctaaa
    20941 ttaattccaa tttttatttg tatttttact tttttgctca tagtaattca aagccagttt
    21001 ttgatggggc aatccataac tgattataat tataaaaagc ccttacagaa cgatcaccaa
    21061 attttagatg aaagtaaaaa ttttggttca aatagtggat ctttcgtcat gtacagcatg
    21121 aagaaagaca aatactatat ttataatgaa aaagaaagta gaaaaagata ttctcctgat
    21181 tcaacttata aaatttattt agcgatgttt ggacttgacc gtcatatcat aagtgataaa
    21241 aattcacgta tgtcatggaa tcataaacat tatcctttcg agtcttggaa taaggaacaa
    21301 gatttaaata cagcaatgca aaattcagtt aattggtact tcgaacgtat tagtaatcaa
    21361 ataccaaaga actatactgc ggctcaactc aagcaattaa attatggtaa tgaaaatttg
    21421 ggaagttata aaaactattg gatggaagat agtttgaaaa tatctaatct tgaacaagta
    21481 atagttttta aaaatatgat ggaacaaaat aaccatttta gtaaaaaagc aaagaatcaa
    21541 ttatcttctt cattattgat taagaaaaat gaaaagtatg aactgtatgg gaaaacaggt
    21601 acaggtatag taaacgggaa gtataataat gggtggtttg taggttacgt aattacaaat
    21661 catgataagt attattttgc tacacattta tcagatggaa acccgtctgg gaaaaatgct
    21721 gaattaatca gtgaaaaaat attaaaagaa atgggtgttt taaatggcca ataagcaagt
    21781 tgaaatatct atggctgaat gggatgttat gaatataata tgggataaaa aatcagtatc
    21841 agctaatgaa attgtagttg aaattcaaaa atataaagaa gttagcgata aaacaattag
    21901 aacattaatc acaagactat ataaaaaaga gattataaaa cgatacaaat cagagaatat
    21961 ttatttttac tcatcaaata ttaaagaaga cgatattaaa atgaaaactg ctaaaacttt
    22021 tcttaataaa ctgtatggag gggacatgaa aagtttagtg ctaaattttg cgaaaaatga
    22081 agaattaaat aacaaagaaa ttgaagaatt gcgagacatt ttaaatgata ttagtaaaaa
    22141 gtaattagag atatgtttca aacattatac atatgtaaac tatacttgac tcttattaaa
    22201 ttagttttgt taataacatt taaaatatat tagtaaagat gagagtgtac ataaaataac
    22261 cattttctgt acactctctt tttatgtcta aataagtatg tattacatag aattatgtgt
    22321 tcaaaaaccc aacaaaaaat ctatgttcac aaaagacctc gtaatcaagt tatggtacac
    22381 taaaggtgta tataggaggt ctgtattttg aaaataggtt atgcaagagt ttcaactgga
    22441 ttacaaaatt tgaatttaca ggaggatcga ttaaatacat atggttgtga aaagatattt
    22501 aatgaccata tgagtggttc aaaaagtaag cgacctggtt tagataaagc aattgaattt
    22561 gcgaggtcag gagatacgat tgttgtttgg agattagata gactaggacg gaacatggag
    22621 gatttaatca cgttagttaa tgaacttaac gaacgaggtg tgagttttca tagtttagaa
    22681 gaaaatataa cgatggataa atcaagttct acaggacaat tattatttca tttattcgca
    22741 gcatttgcag agtttgaacg taatttaatt ttagagcgat catcagccgg tcgaattgca
    22801 gcacgtgcta gaggccgata tggaggtaga cctgaaaaat taaataaaca agatttaaac
    22861 ttacttaaga cactttatga taatggtacg ccaattaaaa caattgcaga gcagtggcaa
    22921 gtttcacgta caactattta tcgttatctc aataaattag aggcaaaaga gaataaaaac
    22981 aagtagagca actaatctag cttactataa tgaatctact aaataatttt atatatcatt
    23041 aacatacaaa gactttgatt caatgtcact cgatgtaaaa gagacgttct gacagcgtct
    23101 aaaatctcat aatattttcc tgttatgaga ttttaataat aacacaagaa aaaagcgtac
    23161 aaattcgtac gcttttttaa tataatacct gtttcactaa tgaacgtttt aagtatcttc
    23221 atcattaact gaaactacag taataatact cgtcaacaat attagtatag ttaaaataga
    23281 aagacttagg actggcataa ccgaactaaa attatatttg aaatataaaa gtgctaatga
    23341 agagagaaat gtaaaaataa taaataccaa agaccatttt tctaatttat tcattggctt
    23401 cacctctttg aacttttata taatcatagg agatattttt actacgattt ataaaaaata
    23461 agaagataat cattattaaa gaaacgatta atataatgtt gaatcctata gtatcaccta
    23521 attcgtttac acctttgcct aatatcggag atacaaagct ttgtattaat aatgaaagag
    23581 atgcccatat agtaaatgag gttctgttgc aaagttgaat ttatagtata attttaacaa
    23641 aaaggagtct tctgtatgaa ctatttcaga tataaacaat ttaacaagga tgttatcact
    23701 gtagctgttg gctactatct aagatatgca ttgagttatc gtgatatatc tgaaatatta
    23761 agggaacgtg gtgtaaacgt tcatcattca acggtctacc gttgggttca agaatatgcc
    23821 ccaattttat atcaaatttg gaagaaaaag cataaaaaag cttattacaa atggcgtatt
    23881 gatgagacgt acatcaaaat aaaaggaaaa tggagctatt tatatcgtgc cattgatgca
    23941 gagggacata cattagatat ttggttgcgt aagcaacgag ataatcattc agcatatgcg
    24001 tttatcaaac gtctcattaa acaatttggt aaacctcaaa aggtaattac agatcaggca
    24061 ccttcaacga aggtagcaat ggttaaagta attaaagctt ttaaacttaa acctgactgc
    24121 cattgtacat cgaaatatct gaataacctc attgagcaag atcaccgtca tattaaagta
    24181 agaaagacaa ggtatcaaag tatcaataca gcaaagaata ctttaaaagg tattgagtgt
    24241 atttacgctc tatataaaaa gaaccgcagg tctcttcaga tctacggatt ttcgccatgc
    24301 cacgaaatta gcatcatgct agcaagttaa gcgaacactg acatgataaa ttagtggtta
    24361 gctatatttt tttactttgc aacagaacca gcatttgttt taatatttgt tccaaagagc
    24421 catcatggct ttgacagagc tcttcttcta tgcaaatgct tttaatccga tccacacgaa
    24481 aattcctata ttcatttctt agcctgcaaa accgattaag taccagttct gttcataaaa
    24541 ccccagtgat ataggctcta tcattctgct ttccggttct tgccctcctg atgcaggata
    24601 ttgaattgat attacccttt tattgcagat tgcagtctga attgctgcaa taacgttatc
    24661 cgccaatgta tttttctgtc cagatgtgct gtacacgtta atactgttct ccaactcctg
    24721 tgcatagttt ttttcaccat gcttcaaaat agatttgatt ttatacatag ctgaatcaaa
    24781 atcctttata aatgattcat ctccatggca atttaaaa
//
