LOCUS       NZ_CP149938            25925 bp    DNA     circular CON 05-APR-2024
DEFINITION  Staphylococcus aureus strain BSN124 plasmid pUSA04, complete
            sequence.
ACCESSION   NZ_CP149938
VERSION     NZ_CP149938.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38637702
            Assembly: GCF_037948675.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 25925)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN124 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25925)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN124
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: CP043386, CP014445
            Genome Coverage                   :: 148.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_037948675.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 22:12:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,864
            Genes (coding)                    :: 2,774
            CDSs (with protein)               :: 2,774
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 47 of 90
            Pseudo Genes (incomplete)         :: 44 of 90
            Pseudo Genes (internal stop)      :: 17 of 90
            Pseudo Genes (multiple problems)  :: 17 of 90
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP149938.1.
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University, Detroit MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..25925
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN124"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pUSA04"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2021-09-17"
                     /collected_by="Andrew D. Berti"
     gene            join(25716..25925,1..465)
                     /locus_tag="UXR22_RS14575"
                     /old_locus_tag="UXR22_14575"
     CDS             join(25716..25925,1..465)
                     /locus_tag="UXR22_RS14575"
                     /old_locus_tag="UXR22_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <524..625
                     /locus_tag="UXR22_RS14580"
                     /old_locus_tag="UXR22_14580"
                     /pseudo=""
     CDS             <524..625
                     /locus_tag="UXR22_RS14580"
                     /old_locus_tag="UXR22_14580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /name="GNAT family N-acetyltransferase"
     gene            718..1512
                     /gene="aph(3')-IIIa"
                     /locus_tag="UXR22_RS14585"
                     /old_locus_tag="UXR22_14585"
     ARG             719..1509
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            1994..>2469
                     /locus_tag="UXR22_RS14590"
                     /old_locus_tag="UXR22_14590"
                     /pseudo=""
     CDS             1994..>2469
                     /locus_tag="UXR22_RS14590"
                     /old_locus_tag="UXR22_14590"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /name="WYL domain-containing protein"
     gene            complement(2528..3202)
                     /locus_tag="UXR22_RS14595"
                     /old_locus_tag="UXR22_14595"
     CDS             complement(2528..3202)
                     /locus_tag="UXR22_RS14595"
                     /old_locus_tag="UXR22_14595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105987.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            3464..3649
                     /locus_tag="UXR22_RS14600"
                     /old_locus_tag="UXR22_14600"
     CDS             3464..3649
                     /locus_tag="UXR22_RS14600"
                     /old_locus_tag="UXR22_14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(3872..4450)
                     /locus_tag="UXR22_RS14605"
                     /old_locus_tag="UXR22_14605"
     CDS             complement(3872..4450)
                     /locus_tag="UXR22_RS14605"
                     /old_locus_tag="UXR22_14605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(4714..5094)
                     /gene="blaI"
                     /locus_tag="UXR22_RS14610"
                     /old_locus_tag="UXR22_14610"
     ARG             complement(4718..5094)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(5084..6841)
                     /gene="blaR1"
                     /locus_tag="UXR22_RS14615"
                     /old_locus_tag="UXR22_14615"
     ARG             complement(5088..6841)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            6948..7793
                     /gene="blaZ"
                     /locus_tag="UXR22_RS14620"
                     /old_locus_tag="UXR22_14620"
     ARG             6949..7790
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(8319..8738)
                     /locus_tag="UXR22_RS14625"
                     /old_locus_tag="UXR22_14625"
     CDS             complement(8319..8738)
                     /locus_tag="UXR22_RS14625"
                     /old_locus_tag="UXR22_14625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            8862..9833
                     /locus_tag="UXR22_RS14630"
                     /old_locus_tag="UXR22_14630"
     CDS             8862..9833
                     /locus_tag="UXR22_RS14630"
                     /old_locus_tag="UXR22_14630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(10005..10097)
                     /locus_tag="UXR22_RS14635"
                     /old_locus_tag="UXR22_14635"
     CDS             complement(10005..10097)
                     /locus_tag="UXR22_RS14635"
                     /old_locus_tag="UXR22_14635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(10254..10601)
                     /locus_tag="UXR22_RS14640"
                     /old_locus_tag="UXR22_14640"
     CDS             complement(10254..10601)
                     /locus_tag="UXR22_RS14640"
                     /old_locus_tag="UXR22_14640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(10620..11237)
                     /gene="cadD"
                     /locus_tag="UXR22_RS14645"
                     /old_locus_tag="UXR22_14645"
     ARG             complement(10624..11237)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(12353..12547)
                     /locus_tag="UXR22_RS14650"
                     /old_locus_tag="UXR22_14650"
     CDS             complement(12353..12547)
                     /locus_tag="UXR22_RS14650"
                     /old_locus_tag="UXR22_14650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            12657..13349
                     /locus_tag="UXR22_RS14655"
                     /old_locus_tag="UXR22_14655"
     CDS             12657..13349
                     /locus_tag="UXR22_RS14655"
                     /old_locus_tag="UXR22_14655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(13517..13666)
                     /locus_tag="UXR22_RS14660"
                     /old_locus_tag="UXR22_14660"
     CDS             complement(13517..13666)
                     /locus_tag="UXR22_RS14660"
                     /old_locus_tag="UXR22_14660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(14213..>14502)
                     /locus_tag="UXR22_RS14665"
                     /old_locus_tag="UXR22_14665"
                     /pseudo=""
     CDS             complement(14213..>14502)
                     /locus_tag="UXR22_RS14665"
                     /old_locus_tag="UXR22_14665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(14522..15505)
                     /locus_tag="UXR22_RS14670"
                     /old_locus_tag="UXR22_14670"
     CDS             complement(14522..15505)
                     /locus_tag="UXR22_RS14670"
                     /old_locus_tag="UXR22_14670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_339076672.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYGDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            15931..16674
                     /locus_tag="UXR22_RS14675"
                     /old_locus_tag="UXR22_14675"
     CDS             15931..16674
                     /locus_tag="UXR22_RS14675"
                     /old_locus_tag="UXR22_14675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(16901..17086)
                     /locus_tag="UXR22_RS14680"
                     /old_locus_tag="UXR22_14680"
     CDS             complement(16901..17086)
                     /locus_tag="UXR22_RS14680"
                     /old_locus_tag="UXR22_14680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(17091..17429)
                     /locus_tag="UXR22_RS14685"
                     /old_locus_tag="UXR22_14685"
     CDS             complement(17091..17429)
                     /locus_tag="UXR22_RS14685"
                     /old_locus_tag="UXR22_14685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(17675..18283)
                     /locus_tag="UXR22_RS14690"
                     /old_locus_tag="UXR22_14690"
     CDS             complement(17675..18283)
                     /locus_tag="UXR22_RS14690"
                     /old_locus_tag="UXR22_14690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(18769..19668)
                     /locus_tag="UXR22_RS14695"
                     /old_locus_tag="UXR22_14695"
     CDS             complement(18769..19668)
                     /locus_tag="UXR22_RS14695"
                     /old_locus_tag="UXR22_14695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(19767..21233)
                     /gene="msr(A)"
                     /locus_tag="UXR22_RS14700"
                     /old_locus_tag="UXR22_14700"
     ARG             complement(19771..21233)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            21707..22381
                     /locus_tag="UXR22_RS14705"
                     /old_locus_tag="UXR22_14705"
     CDS             21707..22381
                     /locus_tag="UXR22_RS14705"
                     /old_locus_tag="UXR22_14705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <22439..22816
                     /locus_tag="UXR22_RS14710"
                     /old_locus_tag="UXR22_14710"
                     /pseudo=""
     CDS             <22439..22816
                     /locus_tag="UXR22_RS14710"
                     /old_locus_tag="UXR22_14710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            22813..23694
                     /locus_tag="UXR22_RS14715"
                     /old_locus_tag="UXR22_14715"
                     /pseudo=""
     CDS             22813..23694
                     /locus_tag="UXR22_RS14715"
                     /old_locus_tag="UXR22_14715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            23810..24739
                     /locus_tag="UXR22_RS14720"
                     /old_locus_tag="UXR22_14720"
     CDS             23810..24739
                     /locus_tag="UXR22_RS14720"
                     /old_locus_tag="UXR22_14720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            24732..25469
                     /locus_tag="UXR22_RS14725"
                     /old_locus_tag="UXR22_14725"
     CDS             24732..25469
                     /locus_tag="UXR22_RS14725"
                     /old_locus_tag="UXR22_14725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            25483..>25659
                     /locus_tag="UXR22_RS14730"
                     /old_locus_tag="UXR22_14730"
                     /pseudo=""
     CDS             25483..>25659
                     /locus_tag="UXR22_RS14730"
                     /old_locus_tag="UXR22_14730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     ARG             complement(18773..19668)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(19768..21233)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(18770..19668)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             6949..7793
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(14010..14157)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(14216..14391)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(14523..15505)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.39"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15932..16674
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tacaaatggc gtattgatga gacgtatatc aaaataaaag gaaaatggag ctatttatat
       61 cgtgccattg atacagaggg acatacatta gatatttggt tgcgtaagca acgagataat
      121 cattcagcat atgcgtttat caaacgtctc attaaacaat ttggtaaacc tcaaaaggta
      181 attacagatc aggcaccttc aacgaaggta gcaatggtta aagtaattaa agcttttaaa
      241 cttaaacctg actgccattg tacatcgaaa tatctgaata acctcattga gcaagatcac
      301 cgtcatatta aagtaagaaa gacaaggtat caaagtatca atacagcaaa gaatacttta
      361 aaaggtattg agtgtattta cgctctatat aaaaagaacc gcaggtctct tcagatctac
      421 ggattttcgc catgccacga aattagcatc atgctagcaa gttaaacgaa cactgacatg
      481 atatattagt gattagctat attttttact ttgcaacaga accgcttgta aattctatca
      541 taattgtggt ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaaagc
      601 tgttttctgg tatttaaggt tttagaatgc aaggaacagt gaattggagt tcgtcttgtt
      661 ataattagct tcttggggta tctttaaata ctgtagaaaa gaggaaggaa ataataaatg
      721 gctaaaatga gaatatcacc ggaattgaaa aaactgatcg aaaaataccg ctgcgtaaaa
      781 gatacggaag gaatgtctcc tgctaaggta tataagctgg tgggagaaaa tgaaaaccta
      841 tatttaaaaa tgacggacag ccggtataaa gggaccacct atgatgtgga acgggaaaag
      901 gacatgatgc tatggctgga aggaaagctg cctgttccaa aggtcctgca ctttgaacgg
      961 catgatggct ggagcaatct gctcatgagt gaggccgatg gcgtcctttg ctcggaagag
     1021 tatgaagatg aacaaagccc tgaaaagatt atcgagctgt atgcggagtg catcaggctc
     1081 tttcactcca tcgacatatc ggattgtccc tatacgaata gcttagacag ccgcttagcc
     1141 gaattggatt acttactgaa taacgatctg gccgatgtgg attgcgaaaa ctgggaagaa
     1201 gacactccat ttaaagatcc gcgcgagctg tatgattttt taaagacgga aaagcccgaa
     1261 gaggaacttg tcttttccca cggcgacctg ggagacagca acatctttgt gaaagatggc
     1321 aaagtaagtg gctttattga tcttgggaga agcggcaggg cggacaagtg gtatgacatt
     1381 gccttctgcg tccggtcgat cagggaggat atcggggaag aacagtatgt cgagctattt
     1441 tttgacttac tggggatcaa gcctgattgg gagaaaataa aatattatat tttactggat
     1501 gaattgtttt agtacctaga tttagatgtc taaaaagctt taactacaag ctttttagac
     1561 atctaatctt ttctgaagta catccgcaac tgtccatact ctgatgtttt atatcttttc
     1621 taaaagttcg ctagatagag ttctatatta gagatgtaaa gagttttggt gaagaggttt
     1681 gtgagtatgg cttttataac cagggtgcaa tgagaagcac taacagcagc tagcttaaga
     1741 acgcatagga tatacttttt atggaagtca cagaggagga ataaaatttg aacaggatta
     1801 acagagtaac ctctattctt attcagctgc aatcaaaaaa ataattcctg ccaaagaaat
     1861 tgcacagcga tttaatataa gcttaaggac agtttacaga gatatccgga cacttgaaga
     1921 agccggaata ccaattggat ctgaggccgg aaaaggatat tttcttgtag agggcttcct
     1981 acttctgccg gtaatgttta cagcggcgga agtgggtgca ttgattacag cagggaaatt
     2041 tttaaattgc catggagatg aatcatttat aaaggatttt gattcagcta tgtataaaat
     2101 caaatctatt ttgaagcatg gtgaaaaaaa ctatgcacag gagttggaga acagtattaa
     2161 cgtgtacagc acatctggac agaaaaatac attggcggat aacgttattg cagcaattca
     2221 gactgcaatc tgcaataaaa gggtaatatc aattcaatat cctgcatcag gagggcaaga
     2281 accggaaagc agaatgatag agcctatatc actggggttt tatgaacaga actggtactt
     2341 aatcggtttt gcaggctaag aaatgaatat aggaattttc gtgtggatcg gattaaaagc
     2401 atttgcatag aagaagagct ctgtcaaagc catgatggct ctttggaaca aatattaaaa
     2461 caaatgctgg ttctgttgca aagtaaaaaa atatagctaa ccactaattt atcatgtcag
     2521 tgttcgctta acttgctagc atgatgctaa tttcgtggca tggcgaaaat ccgtagatct
     2581 gaagagacct gcggttcttt ttatatagag cgtaaataca ctcaatacct tttaaagtat
     2641 tctttgctgt attgatactt tgataccttg tctttcttac tttaatatga cggtgatctt
     2701 gctcaatgag gttattcaga tatttcgatg tacaatgaca gtcaggttta agtttaaaag
     2761 ctttaattac tttagccatt gctaccttcg ttgaaggtgc ctgatctgta attacctttt
     2821 gaggtttacc aaattgttta atgagacgtt tgataaacgc atatgctgaa tgattatctc
     2881 gttgcttacg caaccaaata tctaatgtat gtccctctgc atcaatggca cgatataaat
     2941 agctccattt tccttttatt ttgatgtacg tctcatcaat acgccatttg taataagctt
     3001 ttttatgctt tttcttccaa atttgatata aaattggggc atattcttga acccaacggt
     3061 agaccgttga atgatgaacg tttacaccac gttcccttaa tatttcagat atatcacgat
     3121 aactcaatgc atatcttaga tagtagccaa cagctacagt gataacatcc ttgttaaatt
     3181 gtttatatct gaaatagttc atacagaaga ctcctttttg ttaaaattat actataaatt
     3241 caactttgca acagaacctc atttactata tgggcatctc tttcattatt aatacaaagc
     3301 tttgtatctc cgatattagg caaaggtgta aacgaattag gtgatactat aggattcaac
     3361 attatattaa tcgtttcttt aataatgatt atcttcttat tttttataaa tcgtagtaaa
     3421 aatatctcct atgattatat aaaagttcaa agaggtgaag ccaatgaata aattagaaaa
     3481 atggtctttg gtatttatta tttttacatt tctctcttca ttagcacttt tatatttcaa
     3541 atataatttt agttcggtta tgccagtcct aagtctttct attttaacta tactaatatt
     3601 gttgacgagt attattactg tagtttcagt taatgatgaa gatacttaaa acgttcatta
     3661 gtgaaacagg tattatatta aaaaagcgta cgaatttgta cgcttttttc ttgtgttatt
     3721 attaaaatct cataacagga aaatattatg agattttaga cgctgtcaga acgtctcttt
     3781 tacatcgagt gacattgaat caaagtcttt gtatgttaat gatatataaa attatttagt
     3841 agattcatta tagtaagcta gattagttgc tctacttgtt tttattctct tttgcctcta
     3901 atttattgag ataacgataa atagttgtac gtgaaacttg ccactgctct gcaattgttt
     3961 taattggcgt accattatca taaagtgtct taagtaagtt taaatcttgt ttatttaatt
     4021 tttcaggtct acctccatat cggcctctag cacgtgctgc aattcgaccg gctgatgatc
     4081 gctctaaaat taaattacgt tcaaactctg caaatgctgc gaataaatga aataataatt
     4141 gtcctgtaga acttgattta tccatcgtta tattttcttc taaactatga aaactcacac
     4201 ctcgttcgtt aagttcatta actaacgtga ttaaatcctc catgttccgt cctagtctat
     4261 ctaatctcca aacaacaatc gtatctcctg acctcgcaaa ttcaattgct ttatctaaac
     4321 caggtcgctt actttttgaa ccactcatat ggtcattaaa tatcttttca caaccatatg
     4381 tatttaatcg atcctcctgt aaattcaaat tttgtaatcc agttgaaact cttgcataac
     4441 ctattttcaa aatacagacc tcctatatac acctttagtg taccataact tgattacgag
     4501 gtcttttgtg aacatagatt ttttgttggg tttttgaaca cataattcta tgtaatactt
     4561 acttatttag acaaaaaaca agagtgtaca gaaaatggtt attttctgga cactctcatc
     4621 tttaataata tattttaaat gtcattaaca aaactaattt aataagagtc aagtatggtt
     4681 tacatatgta ttatgtttga aacatacctc taattacttt ttactaatat catttaaaat
     4741 gtctcgcaat tcttcaattt ctttgttatt taattcttca tttttcgcaa aattcagcac
     4801 taaacttttc atatcccctc catacagttt attaagaaag gttttagcag ttttcatttt
     4861 aatatcgtct tctttaatat ttgatgagta aaaataaata ttttctgatt tgtatcgttt
     4921 tataatctct tttttatata gtcttgtgat taatgttcta atcgttttat cactaacttc
     4981 tttatatttt tgaatttcaa ctacaatttc attagctgat actgattttt tatcccatat
     5041 tatattcata acatcccatt cagccataga tatttcaact tgcttattgg tcatttaaaa
     5101 cacccattcc ttttaatatt ttttcactta ttaattcagc atttttccca gacgggtttc
     5161 catctgataa atgtgtagca aaataatact tatcatgatt tgtaattacg taacctacaa
     5221 accacccatt attatacttc ccgtttacta tacctgtacc tgttttccca tacagttcat
     5281 acttttcatt tttcttaatc aataatgaag aagataattg attctttgct tttttactaa
     5341 aatggttatt ttgttccatc atatttttaa aaactattac ttgttcaaga ttagatattt
     5401 tcaaactatc ttccatccaa tagcttttat aacttcccaa attttcatta ccataattta
     5461 attgcttgag ttgagccgca gtatagttct ttggtatttg attactaata cgttcgaagt
     5521 accaattaac tgaattttgc attgctgtat ttaaatcttg ttccttattc caagactcga
     5581 aaagataatg tttatgattc catgacatac gtgaattttt atcacttata atatgacggt
     5641 caagtccaaa cagtgctaaa taaattttgt aagttgaatc aggagaatat ctttttctac
     5701 tttctttttc attataaata tagtatttgt ctttcttcat gctgtacata acgaaagatc
     5761 cactatttga accaaaattt ttactttcat ctaaaatttg gtaatcgctt tgtaagggct
     5821 ttttataatt ataatcagtt aaggattgcc ccattaaaaa ctggctttga attatcatga
     5881 taaaaaaagt aaaaatacaa ataaaaatta gaattaattt tgactgcttt ttcagatcgg
     5941 cttcttttat attaattaat ctacttttga gtaatgattt tttaccatta aatgaatggc
     6001 ttaatatatt tttgttggaa aatggggttt ttaatacgga gtccataata gattccgcat
     6061 aagttttaaa ttcatttttg ttaatattat taaggacaaa tctatcggct tctacttcat
     6121 tgtcatgaat tatctttctt tttacaatat gtactaatgg attgtaactc ataataatag
     6181 agaagatatt aaagataatt aaatgtaaag tatctctatt tttagcatga gcatattcat
     6241 gcagtattat atattttagt cttttatcaa ttacactttt aaaatatgaa ctaggaatca
     6301 aaataatata tttcccatac caaaaagtta ttggagattg aatagcctct gcttttcgaa
     6361 tcacaatatt ttttttatat tgatggttga aaagtatcgt atctatttta tttttttcat
     6421 tttcgtttag ataaagtgac tgtttcttta aatatttaag atataataag gctttcaaaa
     6481 atttaaaact taaaataata actaaaacta tccaaataac tgtgcagata ttatcaattg
     6541 aatcccaatt aaacttatgg atatctgttg tgaactcttg aataggtttg gtggtattta
     6601 tgttatggtt caaatcgtgt gacttacttt caactgtggg cgcttgatta ttcacattat
     6661 taaattttat aaaagagaat ttaattggga taaaaggaat taatccagca agcatagtta
     6721 gataccaaac tttataattt aaactataat taaaatagcg ttttaatatg tacctaaaaa
     6781 atactaacaa tagaaatata aaacaaaagc ttactacgct cattattagt aatttagcca
     6841 ttttgacacc ttctttcaaa tatttataat aaacaattga catcaatatt acaattgtaa
     6901 tattattgat ttataaaaat tacaactgta atatcggagg gtttattttg aaaaagttaa
     6961 tatttttaat tgtaattgct ttagttttaa gtgcatgtaa ttcaaacagt tcacatgcca
     7021 aagagttaaa tgatttagaa aaaaaatata atgctcatat tggtgtttat gctttaaata
     7081 ctaaaagtgg taaggaagta aaatttaatt cagataagag atttgcctat gcttcgactt
     7141 caaaagcgat aaatagtgct attttgttag aacaagtacc ttataataag ttaaataaaa
     7201 aagtacatat taacaaagat gatatagttg cttattctcc tattttagaa aaatatgtag
     7261 gaaaagatat cactttaaaa gaacttattg aggcttcaat gacatatagt gataatacag
     7321 caaacaataa aattataaaa gaaatcggtg gaatcaaaaa agttaaacaa cgtctaaaag
     7381 aactaggaga taaagtaaca aatccagtta gatatgagat agaattaaat tactattcac
     7441 caaagagcaa aaaagatact tcaacgcctg ctgctttcgg caagacttta aataaactta
     7501 tcgcaaatgg aaaattaagc aaaaaaaata aaaatttctt acttgattta atgtttaata
     7561 ataaaaacgg agacacttta attaaagatg gtgttccaaa agactataag gttgctgata
     7621 aaagtggtca agcaataaca tatgcttcta gaaatgatgt tgcttttgtt tatcctaagg
     7681 gccaatctga acctattgtt ttagtcattt ttacgaataa agacaataaa agtgataagc
     7741 caaatgataa gttgataagt gaaaccgcca agagtgtaat gaaggaattt taatattcta
     7801 aatgcataat aaatactgat aacatcttat agtttgtatt atattttgta ttatcgttga
     7861 catgtataat tttgatatca aaaactgatt ttccctttat tattttcgag atttattttc
     7921 ttaattctct ttaacaaact agaaatattg tatatacaaa aaatcataaa taatagatga
     7981 atagtttaat tataggtgtt catcaatcga aaaagcaacg tatcttattt aaagtgcgtt
     8041 gcttttttct catttataag gttaaataat tctcatatat caagcaaagt gacaatagca
     8101 ttttacaagt attttttatt gttcgattag ggtaaaccta aataatacat aaattatatt
     8161 acaatatgtt tattatagag gctaaagtat cttagaaatt tggatagtag gtttttcggg
     8221 aataaaagta tagttggctt taatatataa ttaagctaag ctatcattta tatttactcg
     8281 attataattc gcacttcaac ttttttataa cgtaaaaatt aaaacgtagt tttatttatc
     8341 tttagtaata tctttttaaa cactacagtt tcttcattag ttaaattagc gaagtaatga
     8401 ttattaagtt gataggcttt cttttctaat gttggccata agtcttttgc tttatttgta
     8461 ctgtttatta gcacagttct tctattttca ttatcagttt gacgtgttat tagatccttt
     8521 ttggacatct tatctaatat tccagatatt gttgaaggtt ctaaatttaa agtattacca
     8581 atcgctttag gtgtattcaa attactatta atcaagcaat tcaaaacacc atattctgct
     8641 ggagtaatat tatagggact taataaactt ttaaaatgtt taaaaactct attctgagaa
     8701 gtactcaaca aataatttat acaattatct aattccacaa ctaaaacctc tcttaaatca
     8761 ttagtattga ctcgcttatc atatcatgat aagttttgta ggaaaatagt tttgcaacaa
     8821 aaacatactt ctacaaaaca attgtgaaag aaggctaata aatgttcaat gcggtagtag
     8881 tgagaaaaag tgcatcaaat gttagttata aagtagaaaa agttgatgaa tctcatttat
     8941 cgaagggtga tgtattagta aaagtggtat actcttcaat aaattataag gatatgctag
     9001 ctttacaata taaaggcggt gtaattagag attatcctat gattcctggt atagattttg
     9061 caggtattgt tgaatcaagt tcgaatgata agtttaaaga aggcgataat gtattagtta
     9121 ctggttatga tgttggcgtg acacatacag gtggattttc agaatatgca caagtgcctg
     9181 gagagtggat tgttcctatt ccccaagaaa tgtctattaa agagtctatg gtatatggca
     9241 cagccggttt tacggcagca ttatcaattt ttgaactaga aaaatatgga atgaatatca
     9301 aatcacaacc tgaaatttta gtgtctgggg ctacaggtgg tgtgggcagt gttgctatac
     9361 aaattttaca taaaattgga tatgaaaata tcactgctat cgtaagaaaa gaaaagcaaa
     9421 tagaaatcgc aaaaaaatta ggtgcaaaac aagtaataat aattgaagat gataataaac
     9481 cgcttaaaaa aggtattttt gattatttct tagatacagt ggggagtaat gtaacattat
     9541 acggtttaaa acgtctaaat tatcaaggtg ttgctactgt atgtggaaat gtagcaggaa
     9601 attcacttaa cgctaatata ttaccgttta ttcttagagg tattaaatta attggcattg
     9661 attctgtata tgttgatcat aatatccgtg aagatatatg gagtaagtta gcaaatgaat
     9721 ggaatatagg aaattcactt ctatacaatg aaattggatt tgaagaattc tataaaacga
     9781 tagatcagct tttaaaagga caacatttag gaagaactat tttaaaagta taagtgtgag
     9841 tattcattaa tacatttact attaattcaa tcattttgca tttctctact aaccagtgtt
     9901 ataatttata taacgaaaat gattaacaat taatgcacca atccccacac tattgcagta
     9961 gtgtggggat tttttcgatg ctggcttata aagtcgccta ttaattattt gttgcgttta
    10021 ctaagccaat aagtataata cgcaacagca cagccactga tgactggtgc tatgatgtga
    10081 acgaaaatga ttagcaaagt aatgcacctc ctctcttcgt caattgacgc ctgagagata
    10141 ggcgactcta ttattatacc atctgtgaat atacaagcat atctacttcc gataagtcgt
    10201 cttatgttat ataactttgt tttttatagt atcaagacaa gaagaaactc gtttcaaaaa
    10261 ccctcatgat ttttagagaa aaactctctt atttcatcgt ctttaataaa ataatatgcc
    10321 atctttccat ctttataaaa atcaagtacc tcatttttat ataaaagcct taaatgatgt
    10381 gaagttgaag caacactcat tttcaatatc aaagaaatat cacaaacaca caactcatct
    10441 tctttaatca aagataatat gattttcaat ttcttctcat cacaaatttt ttctaaaatg
    10501 ttaagtaatt tcttagattt atcatcttct aaaaaactta aagcattgtt aactttatcc
    10561 tcatgtacac agatcacatc acaagtattt tcataactca tataaaatca caccctaaat
    10621 taaaatataa atcctaaaat tgtttgaata gtgtcatttt caataataat aaataaacct
    10681 aaagctatat aaataatagc cataatccaa cgactaaatt tctcaacaat ttctccaatt
    10741 cctggaatat tagctaattt ttgtgcagta aacaccaaga agaaaattaa aattaaaaag
    10801 acaaacagag taagtaataa attagtaaca cttaatgtca caaaatacgg aacaaataaa
    10861 ccaatattat cggcgccaca acttgctatc gtaacaattg caaccgtacc aactaattta
    10921 gacaatcctt tttcattcaa ttctttttta gctctctttt ctccttcaca atcatcataa
    10981 atagccactt taattccaag ataaattggt attaaaccca ataaacctaa tatccacttt
    11041 tctggaacat aatttaatac aaaagctaaa aacaaactaa ctaatattaa aataatagac
    11101 cctaaatatt gaccaacata aatatctcta tattcttttc tagtctttgc tctagcaaaa
    11161 aatattaata aaattactaa taaatcaact gctgtagcaa tataaagaac agcagcagca
    11221 acaaccgttt gaatcataat acacctcatt caaaaatatt tttgaatgta ttataactta
    11281 tatttttaaa taatcatagg tgctttattc caattgcttt attgacgttg agcctcggaa
    11341 cccttaacaa tcccaaaact tgtcgaatgg tcggcttaat agctcacgct atgccgacat
    11401 tcgtctgcaa gtttagttaa gggttcttct caacatcaat aaattttttc ggcataaatg
    11461 cgtgtctatg cgtagacatg gagacacttc agaattatgg agtgattaca tgagtttaac
    11521 tatttttctt tattcagttt taggaagttt attagcaaat tatatctacg aaaaatcttc
    11581 aaaataaata actttttcgg ttctactttg tacactttat ctacctggta gacctaattg
    11641 ttattgcttt acaggtctaa aattcgtcgt tataatctag ttaaatcccg taagggcgca
    11701 cttatacgtc ggataaatcg acatgtgcaa aaacgtaatc gaccttcgtc gattttttta
    11761 tttcaaaatt aaagaaacgg cttgagatat tccgagcagt tataaaaatt aatttgcgtt
    11821 gaatattgct actacattct tgaaaaagtg atgtagattt atagcccata acttttttga
    11881 attacatcga cgatacggcg tcgaaagaaa aataaataga ccgtatgaaa gaaaaagcta
    11941 cctcacttta tctggggtag cttttatttt ttatgccctt attttgaatt ttaagagggc
    12001 attttaaaga tttaggggtg attcatatag ttttatatct aaaacttata tatgctttta
    12061 aaacgcaaat atgagccaaa taaatatatg ctattttcaa aaacaaaaat ttgagcaaaa
    12121 acaataacta tttttagaca ctgcccattt acatgcaaat taaaaattag cataaaattc
    12181 tttaaaactt ccccacgttt ttctaaattc ctgtagggcg tttttatcaa aaatcaagac
    12241 aagaagaaac tcgttcacac tcgtttcaaa aaaacaagaa atctaatcta tacacctacc
    12301 gttttccaac cccctcaaag catacaaatt aaaaacaaaa ttattcataa tcttactttc
    12361 ttttaacaaa aacataaaaa ccataaatag acaaattaac tatcaaaggc aataaacagt
    12421 ataaaaaaac cacgaataaa tcttcatcaa catctaaaat aaaaaagaat aaaacaatta
    12481 acaaaatact aattaacaaa cctaaaagtg gcaaactttt tatatatttt tctaaatttt
    12541 cattcataaa atagactcct ttcaaaaata tgtttataaa tatattaaaa taaatattga
    12601 ttttataaag cgcttactta tacaattaaa atatcttatt atcttggagg tatcaaatga
    12661 aaattataaa attattttca ataatttcct tgttcctact ggtatttagc gcgaattttt
    12721 ctaatgctta cgcaaatgaa gaacaaaaaa gttctttact agaaaatcaa aaagaaaaat
    12781 tgaaaagcaa aaacatcgaa gtatcacaaa tgaccaagaa agaaataagt tttctagaac
    12841 aattgcaaaa taaaaatgaa gatatgcaaa aattcgaaaa gcaaatgaaa aaagaaggat
    12901 ttaaaaaaat aaagctagaa gacaaaaatt ctaaattaaa atatctagct acagaagcaa
    12961 atgataaaaa tgcatatggc tacatagcta ataacgctta taaaaatgaa aaaacaaaag
    13021 aaattgtagt ttctgaaaca atatatgata actacaacaa aaaaatcaca aaattcattg
    13081 ccgaaaaaag aagtatgact gaaaacaaag agggaaaaat acttattaac aaaaattacg
    13141 ttgaatataa ggctgaaaaa gttgataaaa acagaccggt aacatatgca ggattcaaat
    13201 ggaacggcaa agcattcgct tgtagtatgg ctggacttta tgcatgtgct cactactgtg
    13261 gagtatgggc aatcgtaaat ccaatagccg gcggtgtatg tgaagcagtt tgcggaactg
    13321 catttgcagc tggatgctct gtaggttgat tttattccaa ttgttttatt gacgttgagc
    13381 ctcggaaccc ttaacaatcc caaaacttgt cgaatggtcg gcttaatagc tcacgctatg
    13441 ccgacattcg tctgcaagtt tagttaaggg ttcttctcaa catcaataaa ttttttcggc
    13501 ataaatacga tgttccttat ttatcctcat aaaaaacaat agctgaaata tataaccaat
    13561 tactgtgtgt ttgaatttct aatacatgaa tatcattctt taaaaaccta ttaacttgtt
    13621 tatctaattg acgatgagta aaagtagcga aagttttaat cttcatgata tctctccttt
    13681 tataaaaata gcaatcctta ttacaatatt aaacactttt attttggatt ttaagaggca
    13741 ttttgaagac ttagaggcaa atcatatagg ttttgtactt aaaaatctat acagtctctt
    13801 aaaacgcaaa tatgagccaa ataaatatat gctaatttca caaacaaaaa tttcagcaaa
    13861 atcagtgact aattttttag atactgccca tttacatgca aatttaaaaa ttagcataaa
    13921 atactttaaa acttccccat gtttttctaa attcctgcag ggcttttctt atcaaaaact
    13981 tagaaatttt aatttaactc taaaatctcc gtaagagcat aagggaaatt tgctatcatt
    14041 caaaaatgat agatctggca aggccagaca ttccaagggt tttaagttat tttaaagtga
    14101 tatcatacaa agctgtagtg tcacactttt gtgacactac atacagcatt tgtcacaaaa
    14161 ataagacagc acttttttac agaaaaacaa taaaaaaaga catcagttat cactaatgtc
    14221 ttaaataata attttgcttt tcgaaattcc aaattgcggt aattgaatgt gctttttttc
    14281 ttcgtctgtc gttttatctt catcacttgt attaatcaaa ttaccatctt cggcatcgtc
    14341 taagtttaaa attttatgct tttgtttaag caatccacca taacttaaca tacgttttcg
    14401 atacaaacct ttttctaaat cacttacaat ttcttgattt ttttcgtcgt catcagttaa
    14461 aaagtcagat gatttaacgg aatattttga tgtctcttcg agtgttataa aatcatttga
    14521 attattgatt aaagatatta tattgtttca tgtttttacg gcgcatataa agggcatgtg
    14581 tttcttcaag ttcagttaga attgtttgca ttaaataagc ttgcattgac ttgattgttt
    14641 ccttttggcc tttaactccc ctatcatgta tagctttttt aagtcttttt aaagaagtta
    14701 atatttcatc ctcaatgtcc tctaacatgt aatgcatatc ttcatgcctt gaattaaatg
    14761 atttttttgc tttaagaata acagccttta tgatttctaa atctccataa tcatatttta
    14821 ataaataatt agttagttgt tctgggaatt cttgcaatag catttcttta tcatcaaaat
    14881 tatgtgtaaa ttgatttgaa tgatttgaat gattactaat ttcatttttg tactttatat
    14941 cattcaagtc attcatatca ttattctcag tatcattaaa gtcaatgtca ttaaagtcag
    15001 tatcattagt gttcgatttt cgaacttctg gacgttcgat tttcgaactt ctggacgttc
    15061 gattttcgaa cttctggacg ttcgattttc gaacttcctt ctcgccgtaa ggttcaacat
    15121 cgttttcttc tttttctatt ttgtaaatat cacgttctgt gacaataggt ttcattaaat
    15181 atagaatatt tggtttattt aaaccacgtc gtttttgaat gagtagacca tcgttttcta
    15241 atcctttttt tatttttgtt aacttttctt ttttacaatt taagatttcc attagctttt
    15301 catttgaata aacaaagtaa atgttaccat cttcatcaac ccagctattt ttaatagata
    15361 aatttaagcg atcacgtaag atagcatagg ctattttcat atcattagtt agatttttat
    15421 aattttcact ggtaaagaat actttaggga tttgataaaa tctttctttg taattttctt
    15481 gcactgtaaa atattgattt tgcatgacaa aaaacctctt tccatatttt agtttggtaa
    15541 gaggtaataa aacgttttta tttagcttta catttattta atgatttagg tgcttgcact
    15601 aagatattat tcattatata atacaagtat cgaaaattat ataaataaac agtttctaaa
    15661 cgttttatta ccaaaccccg actattacca gtagttgggg tttttgttat attaagttta
    15721 ttatagcact ttaaataaac ttataaaagg gaaaatatag ctttatcaag ggtttataaa
    15781 cccttgataa atatcataaa cctttcataa acccttgata aaaaggttga tggatgttta
    15841 tttttattta ttaatcactt tattattaag cattataagc ttataatatt ttatcaaggg
    15901 tttataaaca ttttataaag ggttgatgat atgaaaagtg tgaaaaagtt gagtgaagaa
    15961 ttaggggtta gtaagcaaac gatttttaat aatattaagc gattgaatat agagacaata
    16021 aaacaggaaa acacttcgtt tattaaagaa gataccgata tagaaaaaat cattcaaaga
    16081 gtaaatgaaa ataaaaagaa atatggtttt gaaagtacta ctgaagacaa acaaaaaaaa
    16141 gggtcggata atattaattt tgaatcgaaa agcgatgctc aaatagtaga aatccttaaa
    16201 aatcagattg atactttaaa taatcaaatt gaaaaacaag aaagtcgtca tgaaacaaca
    16261 attgaatttt acagaaaaga gttgcaagaa agatcaaaat tgcttgaaaa tcagcaagtt
    16321 ctggcattag agagtaataa aaagattcaa aaattagaaa atcaattaga aaaagaaaaa
    16381 caccttaatt atccctttga tacatctact aacactagac aaaacgttga tgcacaagaa
    16441 aaaacatata ctactaatcc tgtaaatatt aacagagatc aggaagaaac taaagaaaca
    16501 gagattcaat ataaggatat atctggaagt caaagcgacg aaagtacaca aggtgaagaa
    16561 gcaaaaaaag aagacgttcc agctaatcta aatgacaatg atagtgatat agaagaaaag
    16621 agtgaagaaa cggaacctaa aaaggggttt tggagtcgtt tgtttggtag ctaaaataat
    16681 tgattaggca ctaaaagtta taaaatttta gtgtctttta tatagtgaga acttctggta
    16741 atcatcgatt atgtaaacta aagtatttca aataattaac tgtattaata ctctcatcat
    16801 gattgcgtta taaacgttcg ttattgagac aaaatttaat agtactacta cacaaaaaga
    16861 gagtgcgaat tcgcactctc tttttgtgat aaatgaatgg ttaagaaaat aattcatcca
    16921 cagttgtatc aaacaatctt gccaacttaa atgctaatgt caatgtagga tcatatttat
    16981 tgttttctat tgcattaata gtttgcctag acacttttaa ttctttactt aaagtttctt
    17041 gagaaattcc tttttgtttt ctatattctc taattctatt tttcattaat ttaaccttta
    17101 gatgtatatt ttttatttgt agtatagtaa ttaaacagca taagaaatag tgctacaatt
    17161 ataaagaaaa tttctggata ttgagaaaac caagatcctt caatacttgg tgacaaacct
    17221 gtaaatttaa gcactagtgt aaataacata caatatacaa tccaaataaa acttttagcc
    17281 agtatttcaa taaacatttt acgttgtctt tcatcgtatc gatcttgttg tcctttttta
    17341 tctaatgttt ctgaaggtaa atatttgtta gttatagccg tccataaaca agaaaaaatt
    17401 aaaataataa taaaaggaat taaattcatt ataacacctc ataaatgtaa aaagtatttg
    17461 acatttatga gtgtaaatat ttttgataca aatgtcaaat actttttaca ttataatata
    17521 ttttaaaaca ccttattagt aaaacaatta ctatatagaa agctgcgaac tcgtactctt
    17581 ttttcttgta taattattaa aatctcaatt caataatatg ttatggaatt tgagacactg
    17641 tgagagacgc tcatttgcat tgacaatcaa tttatcaaga taatccctta tcatgtttaa
    17701 ttctataaac tgtttgtctt gtgatattaa cttctttcgc aatcttacta atcgctttgc
    17761 cttcttctaa catttccacc acgcgatgat aaataacacg tttctgtggg tctttagcat
    17821 ttggtgaata aagtaaaggg cgccctttat atacgccttt ttccttcgca acttgaatcc
    17881 cttgcgcttg tcgacgttta ctttcatttc tctcttgttc tgaaaccatt gctaatattt
    17941 gaatgattaa atctttcata aacttatcca gtaatggatt gccaattact tcattcatca
    18001 taggtaagct ggtaatcatt aactgaacgt ctttttcttt taaataattc acagtttcaa
    18061 taatttcatc atagttacgt cctaaacgat caatagattc cacaacgaat cgatctccca
    18121 ttctgacaaa attgagtgct tcttgaaata caggtctatt ttccactgac tttcccgact
    18181 gtttctctgt aaagattttc tccacaccaa acgtctttaa attatccaat tgtctttcta
    18241 aattttgatc tatcgatgat actctcgcat aacctataat cattcatctt cactccataa
    18301 taaatataca ccctaatcat acgttttaat tgttataatt tcaacaattc tttttgtatg
    18361 gttagggtgt actcaaagtg tacatatcta taattaaaac ttactaaaaa taaatataga
    18421 ttttttcttt gtaacagaac cgttcatttg aaggtcatct ctatcataaa tatttaaatt
    18481 aactaaaaat tttaatcatc tgtttaatac ttatgaaatg tatttacggt aggtattaaa
    18541 attgatgaaa tttatataag tgctttcaat gaaaatgacc gtttatttat cctcctgatt
    18601 taaggagtta gaaatttcga aaacgattct ttccatttgt tgcatttgtt ccatgtccag
    18661 atatttaata cattatagaa aaccaaagac catcactaat taaacgcagt tttaaaattt
    18721 catcaggatt gccttcgtct ttaaaatggg cctcttttaa tataagttct actctttcat
    18781 acctaactct ttcaatgcca tcgtttcata cgccgattct cctgattcca tagcaaactc
    18841 agcgataaac attgggaata ctgcattgag ttctattata tgctctttca ttcgtggcca
    18901 tatttcacct ccagctttac cgtatgctgt tataagttgc tctaatcctt cgtcgtcgaa
    18961 tacacgatgg tgtcctataa agtccattga tgggtcggag tgggttgctt cagtccagtc
    19021 tatgagacct gtgacgtttg cttggttatc taccattata tgtcctggat gtaagtcccc
    19081 atgtatcatg gtcgcatgtc gaggccatag ttcgtcgttt tctaaccatt gtttccatct
    19141 gttccataat tcatctgata cgccataagt ttctttaact ttattcattc ttctttgaaa
    19201 gtcatttttt atttcttgta tggttttgat atttatatgc tgaacgttaa tgttttcttc
    19261 tggtatgttg tgtaaatcta cgagtgtttc agctaatgtg ttaataaagt tttctggtaa
    19321 tggtttgtgt tcaatttccc atacataatt ttgtatttct ggatctattg tggctgcggg
    19381 tttacctgta agttttgggt aagcaataag gtcttttgca tgtactttcc acttcggtat
    19441 ttcaaatgaa acattcttct gtaagaagtc taccgtttgt ttttcgggtt ttgttcgttt
    19501 ataaacgtca ggtcttcttg gtagtctcaa aacccattct actccatgtt tatcttttcc
    19561 aaatgcaact tgaaaatcaa gtcccgattc attcaatgag attgtttgag gttggatgtg
    19621 taattgatat ttttctgcac atttaataat ttcattatgt cgagtcattt tattggatcc
    19681 ttatttctat tatatttttc ttgtgaacgt attttttata ttgatataaa tgaacctaat
    19741 attcaatata aattagtgta tagtttttaa gttatatcat gaagagattg tcctgttaat
    19801 tcccattttt tatctgatac atgtttaaca aaccttgtat catgtgatgt aaacaaaatg
    19861 attccaggat atttattcat aaacatttct aatgcttcta atgttttaat atctaaaaaa
    19921 ttagttggtt catccaaaat taacatattc gctttcgttg aaaataatac tgctaacgat
    19981 aatttcgttc tttccccacc actcaaaaca ttacaagaac gatcaagtgc ttcatttaaa
    20041 cccaagttat ttaaaatagc tctactgaat gattctgatg aatccgtttc atccattaaa
    20101 tattgcaata atgaaacgtc acgcatgtct tcataagcaa gttgacgata gtatgccatt
    20161 tgcactttag gagaacaatc aattccctct atttggtggt aaatagcttc aagtaaagtt
    20221 gtcttaccta caccatttgc acctacgagc gctatatttt tgccatatgg tatttggaat
    20281 cgtacttgtg ttagcagttt ttgacttcct ttaaccaatg ttagattttg tgcaatgatt
    20341 ggataattat tatggatatc ataaatttta ttttgtggga aattgaattc atgataactt
    20401 tgtggttttt caacttcttc caaatgttcc attctttttt caatatgctt agcttgtttt
    20461 tgagcagcct tctcaaccgt gcctttttgt tttgatgcac ttaaacgatc tggtgctata
    20521 cttttgtttt tttgttttga tgatgcttgt gccatttgtt gcgcttgatt tcgtttagct
    20581 ttactggctt gggacaatct ttgtttttca cttatatact gttcatattg acgttgttgt
    20641 tctaactgtt cttgttcata ttgattttga tactgtgtgt aattaccttt aaacactctt
    20701 attgtgccat cttcttgtat atcccaaatt gtgtcagcaa tttggtctat aagtgctcta
    20761 tcatgactta ctataattaa agtaccatag taatatttta aaatattttt cagataatct
    20821 ttaccaattt tatccaagtg atttgtaggt tcatctaaaa gtaatatcgg actataattt
    20881 gatatgacat tagctaattt atattttgct ttttcaccac cactcatact gtcggttgta
    20941 tgcataggta tatggagttc actcattaaa ctaccgtcta acgtgttaaa atcattttcc
    21001 acatccatgt taagctgttc aaaatattga atttcgccaa ccgtttcaac tgttccagat
    21061 tctggttttg ttttttgagc aatcatattt agtaatgtgg ttttgccagt accattaccc
    21121 ccaataagtg ctattttttc aaattggtaa gcgtaaagat gaccgatgtt aagtgatcgt
    21181 aaatctgtca atttatgatt gatttggtta aatttaattg tatattgttc catatttata
    21241 cactccttgt atatttaaag gacgtgtacg caaaaaaatg agacaggcta ctcccgtctc
    21301 attcacatta cactttcaaa cacttaaaaa tttattatga tgttttagta tttgaaagcg
    21361 tttattattc ctatcgaagg ataaaaaatg acataagtca tcctatgagt gtgtattgcg
    21421 gacaagcctt tttgaattaa tttagttttg tattcaaaaa ggtttatttg agtctcatag
    21481 aagctgtcat tttaatcctc cttcatcgat aaaatagtaa tgttaatata acattttgtt
    21541 ggttttttta caatatatct ctaagtagaa agattatata acaaaagtat aaaaatacaa
    21601 ttttagattg attatacatc tccttaattt agagtgtact cataaaatac ggttctgttg
    21661 caaagttgaa tttataatat aattttaaca aaaaggagtc ttctgtatga actatttcag
    21721 atataaacaa tttaacaagg atgttatcac tgtagccgtt ggctactatc taagatatgc
    21781 attgagctat cgtgatatat ctgaaatatt aagagaacgt ggtgtaaacg ttcatcattc
    21841 aacgatctac cgttgggttc aagaatatgc cccaatttta tatcaaattt ggaagaaaaa
    21901 gcataaaaaa gcttattaca aatggcgtat tgatgagacg tatatcaaaa taaaaggaaa
    21961 atggagctat ttatatcgtg ccattgatac agagggacat acattagata tttggttgcg
    22021 taagcaacga gataatcatt cagcatatgc gtttatcaaa cgtctcatta aacaatttgg
    22081 taagcctcaa aaggtagtta cagatcaggc accttcaacg aaggcagcaa tggctaaaat
    22141 aattaaagct tttaaactta aacctgactg tcattgtaca tcgaaatatc tgaataacct
    22201 cattgagcaa gatcaccgtc atattaaagt aagaaagaca agatatcaaa gtatcaatac
    22261 ggcaaagaat actttaaaag gtattgaatg tatttacgct ctatataaaa agaaccgtag
    22321 gtctcttcag atctacggat tttccccatg ccacgaaatt agcatcatgc tagcaagtta
    22381 aacgaacact gacatgatat attagtgatt agctatattt tttactttgc aacagaacca
    22441 gccatttaat atgactgtta caattactaa gattcaagca ctattacgcc gcacgtatga
    22501 tttcaccact caagttaata atttaacagt agatgattgc gagttactac ttgatgcagc
    22561 aaagcttaaa tttaatgaag aaaccataga cctgacacac actgaattgc aaatcatgca
    22621 tagcttattc cagaacaagg gcaaattcgt cagtcgtaat gcgttaatcg aaaaatgctg
    22681 ggaatcagaa cacttcattg atgacaatac gcttgctgtc aacattacac gtttacgcaa
    22741 aaagctacaa aaactaggac ttacagattt tatcgaaacg aagaaaaatg tcggatatcg
    22801 tgtaggtgac gtatgaattt cttgaaatca atccaacgtg aaatttatat tgtcatcctt
    22861 acttgtgctt tattctactt tatattattc atgtataatg tgccgatgca agcatatatg
    22921 attggtctag gtattgtatt gtttgtttca atgatttact ggggtatcca ttacatgaac
    22981 tttaaaaaag aataaacact acaggaacag aacgaagatt taagaatcga aaaccataaa
    23041 cttcgtaatg actttattaa ctaccaaagt gagttagagt catatttttt aatgtgggtg
    23101 catcaaatca agacaccgat tacagcatca aagttactgc ttgaagatcc tgatgaacac
    23161 gtgatttcta acgtgcgtaa tgaagtctta caaattgata attacacgaa tcttgcactg
    23221 aactatttga aactcatgaa ccaaaagaca tacatggtct ttatggaagt gagtgtagat
    23281 gaattaattc gaccactgat taaacgttat gcgatacagt ttattcatca tcaaacaaag
    23341 ttgcattatg agaaaagtga agcggttata ttaacagatg ccaaatgggc atcaattatg
    23401 attgagcaaa tattaaacaa tgcattaaaa tatgcacgtg gcaaagatgt gtggattacg
    23461 tttgacgaaa atacaaagaa attatcaatc cgagataacg gtatcggcat taatgcgagt
    23521 gatttaccga aaatctttga taaaggtttc tcgggctata acggtagaat aagtgagaaa
    23581 tcaagcggta ttggtttata tattgtcagc acaatctcaa agcgcttagg ccataaagta
    23641 agtgctacat ctacattaaa cgatggttca atattcacca ttcaatttaa ataactccaa
    23701 tctttcattt ttgtaagatt agcggctgtt tttgtaagaa tagataaagg cagccttttc
    23761 taatcgcgcg taagataaag gtaacaacaa actaagaaag gtgccagagg tgaaaaattt
    23821 gaataatata attgaaataa ataacttaac aaagcaatat ggaagtcaga tagcagttaa
    23881 taatttgagt ataactgttg aaagtggaca aatttatggt tttttaggaa gaaatggtgc
    23941 aggcaaaaca actactataa gaatgctttt aggcttaatt aaacctacga aaggtaatat
    24001 taaaatattt gaaaaagagt tcgaaagtaa taaaactgaa attttaaaaa atattggtgc
    24061 tatggttgaa acgccaggtt tttatagtaa tttgacagct aaagagaact taactataaa
    24121 tgctaaaata ttaggtatac aaaaagaaaa tgcaattgaa gaagtgttag aaatagtagg
    24181 actagcttct gaaaaagtaa aattgtttaa aaattattct ttaggtatga agcaacgttt
    24241 agggattgcg agagctttat tgcacaatcc cgaattattg atacttgatg agccgacgaa
    24301 tggattagat cctattggca taaaagaaat tagaaagttg attaaggatc tggctcaatc
    24361 tagaaatata accattttaa tttcaagtca tatattgtca gaaatagagc agttagtaga
    24421 caaggtgggt attattcata acggagtttt gttagaagaa attatgtatg aagatttaaa
    24481 aaaaaagaac agacaattta taagtatatc agtatcagat gaagaaaaag ttgcatgttt
    24541 gttggaaact aacttcggaa tttatgacta taaaattaaa gaaaatggcg aatttaaaat
    24601 ttattcacat attgatagac aacaagaaat taatagatta ttagtattaa acaatattga
    24661 tgttttccag atgagagtga tagaagataa tctagaaact tatttcgaag acttagtagg
    24721 aggtggcaca attggataat ctactccgta cagaatttat taagttaaaa agatcatata
    24781 tgtttctaat aagtatttta ggtacatgcg tagcaccttt tatggtggtt gtagcttctt
    24841 ttattagtat gcggacgaaa gtaccgactc ctaatattgt atttaaacag ttatttgaag
    24901 aagtcagttt atatcatatg ctaattattg gacctcctct atatggggtt ataatagcct
    24961 atttgtttgg aagagaatat atagaagata ctttaaaaaa cttattaatt atacctatat
    25021 ctagagaaag ttttttagta agtaaaataa tattattatt cttgtggatt caaacactat
    25081 ctgttattgc atggttgcta actttaatgc taggtatgct attgcatttt caagggttaa
    25141 gccagagttt aataattgat tcattcttta catttgttat tggcggagtg ttattatgga
    25201 tattatctcc accaataatt attttgtcga tatattttaa aaattatgtt cccacaattg
    25261 ttttaaccat aataattact ttgataaatt taatgactgc taattctgaa catagaggat
    25321 tatttccttg ggctgcagtt ggagacatat ctagaggaac attacctaat acttatccat
    25381 ttctattatc tttaattatc ataattgtta catctatatt cagtgtaatt atattattct
    25441 catactttaa aaaaactgat ataagttaaa aggaggagaa aaatgggttt tatagagcag
    25501 attaaagcat ttattttagg tgtagttgaa gggttgacag aatttgctcc agtatcatca
    25561 acaggtcata tgattattgt tgatgatatg tggttaaaca ctgctgacga tttaggaagt
    25621 gcgtctgcaa ctacttttaa ggtggtaata cagttaggag gttctgttgc aaagttgaat
    25681 ttataatata attttaacaa aaaggagtct tctgtatgaa ctatttcaga tataaacaat
    25741 ttaacaagga tgttatcact gtagccgttg gctactatct aagatatgca ttgagctatc
    25801 gtgatatatc tgaaatatta agagaacgtg gtgtaaacgt tcatcattca acgatctacc
    25861 gttgggttca agaatatgcc ccaattttat atcaaatttg gaagaaaaag cataaaaaag
    25921 cttat
//
