LOCUS       NZ_CP149809            27004 bp    DNA     circular CON 06-APR-2024
DEFINITION  Staphylococcus aureus strain BSN123 plasmid pUSA04, complete
            sequence.
ACCESSION   NZ_CP149809
VERSION     NZ_CP149809.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38637701
            Assembly: GCF_037938875.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27004)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN123 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27004)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN123
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: CP043386, CP014442, CP014445
            Genome Coverage                   :: 109.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_037938875.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 22:27:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,985
            CDSs (total)                      :: 2,903
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 50 of 88
            Pseudo Genes (incomplete)         :: 43 of 88
            Pseudo Genes (internal stop)      :: 16 of 88
            Pseudo Genes (multiple problems)  :: 20 of 88
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP149809.1.
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University College of Pharmacy, Detroit, MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27004
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN123"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pUSA04"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2021-09-15"
                     /collected_by="Andrew D. Berti"
     gene            join(26795..27004,1..465)
                     /locus_tag="UXQ24_RS14760"
                     /old_locus_tag="UXQ24_14760"
     CDS             join(26795..27004,1..465)
                     /locus_tag="UXQ24_RS14760"
                     /old_locus_tag="UXQ24_14760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <606..1241
                     /locus_tag="UXQ24_RS14765"
                     /old_locus_tag="UXQ24_14765"
                     /pseudo=""
     CDS             <606..1241
                     /locus_tag="UXQ24_RS14765"
                     /old_locus_tag="UXQ24_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            1238..1768
                     /gene="sat4"
                     /locus_tag="UXQ24_RS14770"
                     /old_locus_tag="UXQ24_14770"
     ARG             1239..1765
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            1861..2655
                     /gene="aph(3')-IIIa"
                     /locus_tag="UXQ24_RS14775"
                     /old_locus_tag="UXQ24_14775"
     ARG             1862..2652
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3137..>3612
                     /locus_tag="UXQ24_RS14780"
                     /old_locus_tag="UXQ24_14780"
                     /pseudo=""
     CDS             3137..>3612
                     /locus_tag="UXQ24_RS14780"
                     /old_locus_tag="UXQ24_14780"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /name="WYL domain-containing protein"
     gene            complement(3671..4345)
                     /locus_tag="UXQ24_RS14785"
                     /old_locus_tag="UXQ24_14785"
     CDS             complement(3671..4345)
                     /locus_tag="UXQ24_RS14785"
                     /old_locus_tag="UXQ24_14785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001550192.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            4607..4792
                     /locus_tag="UXQ24_RS14790"
                     /old_locus_tag="UXQ24_14790"
     CDS             4607..4792
                     /locus_tag="UXQ24_RS14790"
                     /old_locus_tag="UXQ24_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(5015..5593)
                     /locus_tag="UXQ24_RS14795"
                     /old_locus_tag="UXQ24_14795"
     CDS             complement(5015..5593)
                     /locus_tag="UXQ24_RS14795"
                     /old_locus_tag="UXQ24_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(5857..6237)
                     /gene="blaI"
                     /locus_tag="UXQ24_RS14800"
                     /old_locus_tag="UXQ24_14800"
     ARG             complement(5861..6237)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(6227..7984)
                     /gene="blaR1"
                     /locus_tag="UXQ24_RS14805"
                     /old_locus_tag="UXQ24_14805"
     ARG             complement(6231..7984)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            8091..8936
                     /gene="blaZ"
                     /locus_tag="UXQ24_RS14810"
                     /old_locus_tag="UXQ24_14810"
     ARG             8092..8933
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9462..9881)
                     /locus_tag="UXQ24_RS14815"
                     /old_locus_tag="UXQ24_14815"
     CDS             complement(9462..9881)
                     /locus_tag="UXQ24_RS14815"
                     /old_locus_tag="UXQ24_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            10005..10976
                     /locus_tag="UXQ24_RS14820"
                     /old_locus_tag="UXQ24_14820"
     CDS             10005..10976
                     /locus_tag="UXQ24_RS14820"
                     /old_locus_tag="UXQ24_14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(11148..11240)
                     /locus_tag="UXQ24_RS14825"
                     /old_locus_tag="UXQ24_14825"
     CDS             complement(11148..11240)
                     /locus_tag="UXQ24_RS14825"
                     /old_locus_tag="UXQ24_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(11397..11744)
                     /locus_tag="UXQ24_RS14830"
                     /old_locus_tag="UXQ24_14830"
     CDS             complement(11397..11744)
                     /locus_tag="UXQ24_RS14830"
                     /old_locus_tag="UXQ24_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(11763..12380)
                     /gene="cadD"
                     /locus_tag="UXQ24_RS14835"
                     /old_locus_tag="UXQ24_14835"
     ARG             complement(11767..12380)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13496..13690)
                     /locus_tag="UXQ24_RS14840"
                     /old_locus_tag="UXQ24_14840"
     CDS             complement(13496..13690)
                     /locus_tag="UXQ24_RS14840"
                     /old_locus_tag="UXQ24_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            13800..13937
                     /locus_tag="UXQ24_RS14845"
                     /old_locus_tag="UXQ24_14845"
     CDS             13800..13937
                     /locus_tag="UXQ24_RS14845"
                     /old_locus_tag="UXQ24_14845"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_257241179.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     "
                     /name="hypothetical protein"
     gene            13934..14398
                     /locus_tag="UXQ24_RS14850"
                     /old_locus_tag="UXQ24_14850"
     CDS             13934..14398
                     /locus_tag="UXQ24_RS14850"
                     /old_locus_tag="UXQ24_14850"
                     /inference="COORDINATES: protein motif:HMM:TIGR04450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_102778833.1"
                     /translation="MKKEGFKKIKLEDKNSKLKYLATEANDKNAYGYIANNAYKNEKTK
                     EIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVEYKAEKVDKNRPVTYAGF
                     KWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTAFAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(14566..14715)
                     /locus_tag="UXQ24_RS14855"
                     /old_locus_tag="UXQ24_14855"
     CDS             complement(14566..14715)
                     /locus_tag="UXQ24_RS14855"
                     /old_locus_tag="UXQ24_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(15291..>15581)
                     /locus_tag="UXQ24_RS14860"
                     /old_locus_tag="UXQ24_14860"
                     /pseudo=""
     CDS             complement(15291..>15581)
                     /locus_tag="UXQ24_RS14860"
                     /old_locus_tag="UXQ24_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(15601..16584)
                     /locus_tag="UXQ24_RS14865"
                     /old_locus_tag="UXQ24_14865"
     CDS             complement(15601..16584)
                     /locus_tag="UXQ24_RS14865"
                     /old_locus_tag="UXQ24_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            17010..17753
                     /locus_tag="UXQ24_RS14870"
                     /old_locus_tag="UXQ24_14870"
     CDS             17010..17753
                     /locus_tag="UXQ24_RS14870"
                     /old_locus_tag="UXQ24_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(17980..18165)
                     /locus_tag="UXQ24_RS14875"
                     /old_locus_tag="UXQ24_14875"
     CDS             complement(17980..18165)
                     /locus_tag="UXQ24_RS14875"
                     /old_locus_tag="UXQ24_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(18170..18508)
                     /locus_tag="UXQ24_RS14880"
                     /old_locus_tag="UXQ24_14880"
     CDS             complement(18170..18508)
                     /locus_tag="UXQ24_RS14880"
                     /old_locus_tag="UXQ24_14880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(18754..19362)
                     /locus_tag="UXQ24_RS14885"
                     /old_locus_tag="UXQ24_14885"
     CDS             complement(18754..19362)
                     /locus_tag="UXQ24_RS14885"
                     /old_locus_tag="UXQ24_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(19848..20747)
                     /locus_tag="UXQ24_RS14890"
                     /old_locus_tag="UXQ24_14890"
     CDS             complement(19848..20747)
                     /locus_tag="UXQ24_RS14890"
                     /old_locus_tag="UXQ24_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(20846..22312)
                     /gene="msr(A)"
                     /locus_tag="UXQ24_RS14895"
                     /old_locus_tag="UXQ24_14895"
     ARG             complement(20850..22312)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22786..23460
                     /locus_tag="UXQ24_RS14900"
                     /old_locus_tag="UXQ24_14900"
     CDS             22786..23460
                     /locus_tag="UXQ24_RS14900"
                     /old_locus_tag="UXQ24_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <23518..23895
                     /locus_tag="UXQ24_RS14905"
                     /old_locus_tag="UXQ24_14905"
                     /pseudo=""
     CDS             <23518..23895
                     /locus_tag="UXQ24_RS14905"
                     /old_locus_tag="UXQ24_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            23892..24773
                     /locus_tag="UXQ24_RS14910"
                     /old_locus_tag="UXQ24_14910"
                     /pseudo=""
     CDS             23892..24773
                     /locus_tag="UXQ24_RS14910"
                     /old_locus_tag="UXQ24_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            24889..25818
                     /locus_tag="UXQ24_RS14915"
                     /old_locus_tag="UXQ24_14915"
     CDS             24889..25818
                     /locus_tag="UXQ24_RS14915"
                     /old_locus_tag="UXQ24_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            25811..26548
                     /locus_tag="UXQ24_RS14920"
                     /old_locus_tag="UXQ24_14920"
     CDS             25811..26548
                     /locus_tag="UXQ24_RS14920"
                     /old_locus_tag="UXQ24_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            26562..>26738
                     /locus_tag="UXQ24_RS14925"
                     /old_locus_tag="UXQ24_14925"
                     /pseudo=""
     CDS             26562..>26738
                     /locus_tag="UXQ24_RS14925"
                     /old_locus_tag="UXQ24_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     ARG             complement(19852..20747)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(20847..22312)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(19849..20747)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             1251..1768
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             8092..8936
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     ARG             643..944
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          complement(15057..15221)
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.42e-81"
     Typing          complement(15294..15470)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.258"
                     /coverage="94.0"
                     /evalue="6.2e-68"
     Typing          complement(15602..16584)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17011..17753
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tacaaatggc gtattgatga gacgtatatc aaaataaaag gaaaatggag ctatttatat
       61 cgtgccattg atacagaggg acatacatta gatatttggt tgcgtaagca acgagataat
      121 cattcagcat atgcgtttat caaacgtctc attaaacaat ttggtaaacc tcaaaaggta
      181 attacagatc aggcaccttc aacgaaggta gcaatggtta aagtaattaa agcttttaaa
      241 cttaaacctg actgccattg tacatcgaaa tatctgaata acctcattga gcaagatcac
      301 cgtcatatta aagtaagaaa gacaaggtat caaagtatca atacggcaaa gaatacttta
      361 aaaggtattg aatgtattta cgctctatat aaaaagaacc gcaggtctct tcagatctac
      421 ggattttcgc catgccacga aattagcatc atgctagcaa gttaaacgaa cactgacatg
      481 atatattagt gattagctat attttttact ttgcaacaga accatcattt ttattaaaat
      541 actcttttgt aaaatctttc tgctcttcaa tgtatttaat ttctttacct ctaaatctat
      601 tatagctatt tgatgattac aataaaattg atcttacctt attgcccttg gaagagttag
      661 ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat tgtagaatta
      721 aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc gcaagggagt
      781 atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa ggattgtgcc
      841 gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat gagctgctga
      901 gaatgatatc atggaaggtc ggcatcgaaa caggctttaa atgaagtgta ggcaagaact
      961 ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg tccacctacc
     1021 ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa ttgttcaggg
     1081 cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat gataggaata
     1141 taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc tgcctggata
     1201 gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa tgaaagcagg
     1261 gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta agattatacc
     1321 gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc catatttaaa
     1381 aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg aatatattga
     1441 caatactgat aagataatat atctttacta ccaagacgat aaatgcgtcg gaaaagttaa
     1501 actgcgaaaa aattggaacc ggtacgctta tatagaagat atcgccgtat gtaaggattt
     1561 cagggggcaa ggcataggca gcgcgcttat caatatatct atagaatggg caaagcataa
     1621 aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt gtaaattcta
     1681 tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca actttgaaaa
     1741 agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg agttcgtctt
     1801 gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag gaaataataa
     1861 atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata ccgctgcgta
     1921 aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga aaatgaaaac
     1981 ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt ggaacgggaa
     2041 aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct gcactttgaa
     2101 cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct ttgctcggaa
     2161 gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga gtgcatcagg
     2221 ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga cagccgctta
     2281 gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga aaactgggaa
     2341 gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac ggaaaagccc
     2401 gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt tgtgaaagat
     2461 ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa gtggtatgac
     2521 attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta tgtcgagcta
     2581 ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta tattttactg
     2641 gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac aagcttttta
     2701 gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt tttatatctt
     2761 ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt ggtgaagagg
     2821 tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc agctagctta
     2881 agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat ttgaacagga
     2941 ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaataattc ctgccaaaga
     3001 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     3061 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     3121 cctacttctg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     3181 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     3241 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     3301 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     3361 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     3421 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     3481 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     3541 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     3601 aaacaaatgc tggttctgtt gcaaagtaaa aaaatatagc taaccactaa tttatcatgt
     3661 cagtgttcgc ttaacttgct agcatgatgc taatttcgtg gcatggcgaa aatccgtaga
     3721 tctgaagaga cctgcggttc tttttatata gagcgtaaat acattcaata ccttttaaag
     3781 tattctttgc cgtattgata ctttgatacc ttgtctttct tactttaata tgacggtgat
     3841 cttgctcaat gaggttattc agatatttcg atgtacaatg gcagtcaggt ttaagtttaa
     3901 aagctttaat tactttaacc attgctacct tcgttgaagg tgcctgatct gtaattacct
     3961 tttgaggttt accaaattgt ttaatgagac gtttgataaa cgcatatgct gaatgattat
     4021 ctcgttgctt acgcaaccaa atatctaatg tatgtccctc tgtatcaatg gcacgatata
     4081 aatagctcca ttttcctttt attttgatat acgtctcatc aatacgccat ttgtaataag
     4141 cttttttatg ctttttcttc caaatttgat ataaaattgg ggcatattct tgaacccaac
     4201 ggtagaccgt tgaatgatga acgtttacac cacgttccct taatatttca gatatatcac
     4261 gataactcaa tgcatatctt agatagtagc caacagctac agtgataaca tccttgttaa
     4321 attgtttata tctgaaatag ttcatacaga agactccttt ttgttaaaat tatactataa
     4381 attcaacttt gcaacagaac ctcatttact atatgggcat ctctttcatt attaatacaa
     4441 agctttgtat ctccgatatt aggcaaaggt gtaaacgaat taggtgatac tataggattc
     4501 aacattatat taatcgtttc tttaataatg attatcttct tattttttat aaatcgtagt
     4561 aaaaatatct cctatgatta tataaaagtt caaagaggtg aagccaatga ataaattaga
     4621 aaaatggtct ttggtattta ttatttttac atttctctct tcattagcac ttttatattt
     4681 caaatataat tttagttcgg ttatgccagt cctaagtctt tctattttaa ctatactaat
     4741 attgttgacg agtattatta ctgtagtttc agttaatgat gaagatactt aaaacgttca
     4801 ttagtgaaac aggtattata ttaaaaaagc gtacgaattt gtacgctttt ttcttgtgtt
     4861 attattaaaa tctcataaca ggaaaatatt atgagatttt agacgctgtc agaacgtctc
     4921 ttttacatcg agtgacattg aatcaaagtc tttgtatgtt aatgatatat aaaattattt
     4981 agtagattca ttatagtaag ctagattagt tgctctactt gtttttattc tcttttgcct
     5041 ctaatttatt gagataacga taaatagttg tacgtgaaac ttgccactgc tctgcaattg
     5101 ttttaattgg cgtaccatta tcataaagtg tcttaagtaa gtttaaatct tgtttattta
     5161 atttttcagg tctacctcca tatcggcctc tagcacgtgc tgcaattcga ccggctgatg
     5221 atcgctctaa aattaaatta cgttcaaact ctgcaaatgc tgcgaataaa tgaaataata
     5281 attgtcctgt agaacttgat ttatccatcg ttatattttc ttctaaacta tgaaaactca
     5341 cacctcgttc gttaagttca ttaactaacg tgattaaatc ctccatgttc cgtcctagtc
     5401 tatctaatct ccaaacaaca atcgtatctc ctgacctcgc aaattcaatt gctttatcta
     5461 aaccaggtcg cttacttttt gaaccactca tatggtcatt aaatatcttt tcacaaccat
     5521 atgtatttaa tcgatcctcc tgtaaattca aattttgtaa tccagttgaa actcttgcat
     5581 aacctatttt caaaatacag acctcctata tacaccttta gtgtaccata acttgattac
     5641 gaggtctttt gtgaacatag attttttgtt gggtttttga acacataatt ctatgtaata
     5701 cttacttatt tagacaaaaa acaagagtgt acagaaaatg gttattttct ggacactctc
     5761 atctttaata atatatttta aatgtcatta acaaaactaa tttaataaga gtcaagtatg
     5821 gtttacatat gtattatgtt tgaaacatac ctctaattac tttttactaa tatcatttaa
     5881 aatgtctcgc aattcttcaa tttctttgtt atttaattct tcatttttcg caaaattcag
     5941 cactaaactt ttcatatccc ctccatacag tttattaaga aaggttttag cagttttcat
     6001 tttaatatcg tcttctttaa tatttgatga gtaaaaataa atattttctg atttgtatcg
     6061 ttttataatc tcttttttat atagtcttgt gattaatgtt ctaatcgttt tatcactaac
     6121 ttctttatat ttttgaattt caactacaat ttcattagct gatactgatt ttttatccca
     6181 tattatattc ataacatccc attcagccat agatatttca acttgcttat tggtcattta
     6241 aaacacccat tccttttaat attttttcac ttattaattc agcatttttc ccagacgggt
     6301 ttccatctga taaatgtgta gcaaaataat acttatcatg atttgtaatt acgtaaccta
     6361 caaaccaccc attattatac ttcccgttta ctatacctgt acctgttttc ccatacagtt
     6421 catacttttc atttttctta atcaataatg aagaagataa ttgattcttt gcttttttac
     6481 taaaatggtt attttgttcc atcatatttt taaaaactat tacttgttca agattagata
     6541 ttttcaaact atcttccatc caatagcttt tataacttcc caaattttca ttaccataat
     6601 ttaattgctt gagttgagcc gcagtatagt tctttggtat ttgattacta atacgttcga
     6661 agtaccaatt aactgaattt tgcattgctg tatttaaatc ttgttcctta ttccaagact
     6721 cgaaaagata atgtttatga ttccatgaca tacgtgaatt tttatcactt ataatatgac
     6781 ggtcaagtcc aaacagtgct aaataaattt tgtaagttga atcaggagaa tatctttttc
     6841 tactttcttt ttcattataa atatagtatt tgtctttctt catgctgtac ataacgaaag
     6901 atccactatt tgaaccaaaa tttttacttt catctaaaat ttggtaatcg ctttgtaagg
     6961 gctttttata attataatca gttaaggatt gccccattaa aaactggctt tgaattatca
     7021 tgataaaaaa agtaaaaata caaataaaaa ttagaattaa ttttgactgc tttttcagat
     7081 cggcttcttt tatattaatt aatctacttt tgagtaatga ttttttacca ttaaatgaat
     7141 ggcttaatat atttttgttg gaaaatgggg tttttaatac ggagtccata atagattccg
     7201 cataagtttt aaattcattt ttgttaatat tattaaggac aaatctatcg gcttctactt
     7261 cattgtcatg aattatcttt ctttttacaa tatgtactaa tggattgtaa ctcataataa
     7321 tagagaagat attaaagata attaaatgta aagtatctct atttttagca tgagcatatt
     7381 catgcagtat tatatatttt agtcttttat caattacact tttaaaatat gaactaggaa
     7441 tcaaaataat atatttccca taccaaaaag ttattggaga ttgaatagcc tctgcttttc
     7501 gaatcacaat atttttttta tattgatggt tgaaaagtat cgtatctatt ttattttttt
     7561 cattttcgtt tagataaagt gactgtttct ttaaatattt aagatataat aaggctttca
     7621 aaaatttaaa acttaaaata ataactaaaa ctatccaaat aactgtgcag atattatcaa
     7681 ttgaatccca attaaactta tggatatctg ttgtgaactc ttgaataggt ttggtggtat
     7741 ttatgttatg gttcaaatcg tgtgacttac tttcaactgt gggcgcttga ttattcacat
     7801 tattaaattt tataaaagag aatttaattg ggataaaagg aattaatcca gcaagcatag
     7861 ttagatacca aactttataa tttaaactat aattaaaata gcgttttaat atgtacctaa
     7921 aaaatactaa caatagaaat ataaaacaaa agcttactac gctcattatt agtaatttag
     7981 ccattttgac accttctttc aaatatttat aataaacaat tgacatcaat attacaattg
     8041 taatattatt gatttataaa aattacaact gtaatatcgg agggtttatt ttgaaaaagt
     8101 taatattttt aattgtaatt gctttagttt taagtgcatg taattcaaac agttcacatg
     8161 ccaaagagtt aaatgattta gaaaaaaaat ataatgctca tattggtgtt tatgctttaa
     8221 atactaaaag tggtaaggaa gtaaaattta attcagataa gagatttgcc tatgcttcga
     8281 cttcaaaagc gataaatagt gctattttgt tagaacaagt accttataat aagttaaata
     8341 aaaaagtaca tattaacaaa gatgatatag ttgcttattc tcctatttta gaaaaatatg
     8401 taggaaaaga tatcacttta aaagaactta ttgaggcttc aatgacatat agtgataata
     8461 cagcaaacaa taaaattata aaagaaatcg gtggaatcaa aaaagttaaa caacgtctaa
     8521 aagaactagg agataaagta acaaatccag ttagatatga gatagaatta aattactatt
     8581 caccaaagag caaaaaagat acttcaacgc ctgctgcttt cggcaagact ttaaataaac
     8641 ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt cttacttgat ttaatgttta
     8701 ataataaaaa cggagacact ttaattaaag atggtgttcc aaaagactat aaggttgctg
     8761 ataaaagtgg tcaagcaata acatatgctt ctagaaatga tgttgctttt gtttatccta
     8821 agggccaatc tgaacctatt gttttagtca tttttacgaa taaagacaat aaaagtgata
     8881 agccaaatga taagttgata agtgaaaccg ccaagagtgt aatgaaggaa ttttaatatt
     8941 ctaaatgcat aataaatact gataacatct tatagtttgt attatatttt gtattatcgt
     9001 tgacatgtat aattttgata tcaaaaactg attttccctt tattattttc gagatttatt
     9061 ttcttaattc tctttaacaa actagaaata ttgtatatac aaaaaatcat aaataataga
     9121 tgaatagttt aattataggt gttcatcaat cgaaaaagca acgtatctta tttaaagtgc
     9181 gttgcttttt tctcatttat aaggttaaat aattctcata tatcaagcaa agtgacaata
     9241 gcattttaca agtatttttt attgttcgat tagggtaaac ctaaataata cataaattat
     9301 attacaatat gtttattata gaggctaaag tatcttagaa atttggatag taggtttttc
     9361 gggaataaaa gtatagttgg ctttaatata taattaagct aagctatcat ttatatttac
     9421 tcgattataa ttcgcacttc aactttttta taacgtaaaa attaaaacgt agttttattt
     9481 atctttagta atatcttttt aaacactaca gtttcttcat tagttaaatt agcgaagtaa
     9541 tgattattaa gttgataggc tttcttttct aatgttggcc ataagtcttt tgctttattt
     9601 gtactgttta ttagcacagt tcttctattt tcattatcag tttgacgtgt tattagatcc
     9661 tttttggaca tcttatctaa tattccagat attgttgaag gttctaaatt taaagtatta
     9721 ccaatcgctt taggtgtatt caaattacta ttaatcaagc aattcaaaac accatattct
     9781 gctggagtaa tattataggg acttaataaa cttttaaaat gtttaaaaac tctattctga
     9841 gaagtactca acaaataatt tatacaatta tctaattcca caactaaaac ctctcttaaa
     9901 tcattagtat tgactcgctt atcatatcat gataagtttt gtaggaaaat agttttgcaa
     9961 caaaaacata cttctacaaa acaattgtga aagaaggcta ataaatgttc aatgcggtag
    10021 tagtgagaaa aagtgcatca aatgttagtt ataaagtaga aaaagttgat gaatctcatt
    10081 tatcgaaggg tgatgtatta gtaaaagtgg tatactcttc aataaattat aaggatatgc
    10141 tagctttaca atataaaggc ggtgtaatta gagattatcc tatgattcct ggtatagatt
    10201 ttgcaggtat tgttgaatca agttcgaatg ataagtttaa agaaggcgat aatgtattag
    10261 ttactggtta tgatgttggc gtgacacata caggtggatt ttcagaatat gcacaagtgc
    10321 ctggagagtg gattgttcct attccccaag aaatgtctat taaagagtct atggtatatg
    10381 gcacagccgg ttttacggca gcattatcaa tttttgaact agaaaaatat ggaatgaata
    10441 tcaaatcaca acctgaaatt ttagtgtctg gggctacagg tggtgtgggc agtgttgcta
    10501 tacaaatttt acataaaatt ggatatgaaa atatcactgc tatcgtaaga aaagaaaagc
    10561 aaatagaaat cgcaaaaaaa ttaggtgcaa aacaagtaat aataattgaa gatgataata
    10621 aaccgcttaa aaaaggtatt tttgattatt tcttagatac agtggggagt aatgtaacat
    10681 tatacggttt aaaacgtcta aattatcaag gtgttgctac tgtatgtgga aatgtagcag
    10741 gaaattcact taacgctaat atattaccgt ttattcttag aggtattaaa ttaattggca
    10801 ttgattctgt atatgttgat cataatatcc gtgaagatat atggagtaag ttagcaaatg
    10861 aatggaatat aggaaattca cttctataca atgaaattgg atttgaagaa ttctataaaa
    10921 cgatagatca gcttttaaaa ggacaacatt taggaagaac tattttaaaa gtataagtgt
    10981 gagtattcat taatacattt actattaatt caatcatttt gcatttctct actaaccagt
    11041 gttataattt atataacgaa aatgattaac aattaatgca ccaatcccca cactattgca
    11101 gtagtgtggg gattttttcg atgctggctt ataaagtcgc ctattaatta tttgttgcgt
    11161 ttactaagcc aataagtata atacgcaaca gcacagccac tgatgactgg tgctatgatg
    11221 tgaacgaaaa tgattagcaa agtaatgcac ctcctctctt cgtcaattga cgcctgagag
    11281 ataggcgact ctattattat accatctgtg aatatacaag catatctact tccgataagt
    11341 cgtcttatgt tatataactt tgttttttat agtatcaaga caagaagaaa ctcgtttcaa
    11401 aaaccctcat gatttttaga gaaaaactct cttatttcat cgtctttaat aaaataatat
    11461 gccatctttc catctttata aaaatcaagt acctcatttt tatataaaag ccttaaatga
    11521 tgtgaagttg aagcaacact cattttcaat atcaaagaaa tatcacaaac acacaactca
    11581 tcttctttaa tcaaagataa tatgattttc aatttcttct catcacaaat tttttctaaa
    11641 atgttaagta atttcttaga tttatcatct tctaaaaaac ttaaagcatt gttaacttta
    11701 tcctcatgta cacagatcac atcacaagta ttttcataac tcatataaaa tcacacccta
    11761 aattaaaata taaatcctaa aattgtttga atagtgtcat tttcaataat aataaataaa
    11821 cctaaagcta tataaataat agccataatc caacgactaa atttctcaac aatttctcca
    11881 attcctggaa tattagctaa tttttgtgca gtaaacacca agaagaaaat taaaattaaa
    11941 aagacaaaca gagtaagtaa taaattagta acacttaatg tcacaaaata cggaacaaat
    12001 aaaccaatat tatcggcgcc acaacttgct atcgtaacaa ttgcaaccgt accaactaat
    12061 ttagacaatc ctttttcatt caattctttt ttagctctct tttctccttc acaatcatca
    12121 taaatagcca ctttaattcc aagataaatt ggtattaaac ccaataaacc taatatccac
    12181 ttttctggaa cataatttaa tacaaaagct aaaaacaaac taactaatat taaaataata
    12241 gaccctaaat attgaccaac ataaatatct ctatattctt ttctagtctt tgctctagca
    12301 aaaaatatta ataaaattac taataaatca actgctgtag caatataaag aacagcagca
    12361 gcaacaaccg tttgaatcat aatacacctc attcaaaaat atttttgaat gtattataac
    12421 ttatattttt aaataatcat aggtgcttta ttccaattgc tttattgacg ttgagcctcg
    12481 gaacccttaa caatcccaaa acttgtcgaa tggtcggctt aatagctcac gctatgccga
    12541 cattcgtctg caagtttagt taagggttct tctcaacatc aataaatttt ttcggcataa
    12601 atgcgtgtct atgcgtagac atggagacac ttcagaatta tggagtgatt acatgagttt
    12661 aactattttt ctttattcag ttttaggaag tttattagca aattatatct acgaaaaatc
    12721 ttcaaaataa ataacttttt cggttctact ttgtacactt tatctacctg gtagacctaa
    12781 ttgttattgc tttacaggtc taaaattcgt cgttataatc tagttaaatc ccgtaagggc
    12841 gcacttatac gtcggataaa tcgacatgtg caaaaacgta atcgaccttc gtcgattttt
    12901 ttatttcaaa attaaagaaa cggcttgaga tattccgagc agttataaaa attaatttgc
    12961 gttgaatatt gctactacat tcttgaaaaa gtgatgtaga tttatagccc ataacttttt
    13021 tgaattacat cgacgatacg gcgtcgaaag aaaaataaat agaccgtatg aaagaaaaag
    13081 ctacctcact ttatctgggg tagcttttat tttttatgcc cttattttga attttaagag
    13141 ggcattttaa agatttaggg gtgattcata tagttttata tctaaaactt atatatgctt
    13201 ttaaaacgca aatatgagcc aaataaatat atgctatttt caaaaacaaa aatttgagca
    13261 aaaacaataa ctatttttag acactgccca tttacatgca aattaaaaat tagcataaaa
    13321 ttctttaaaa cttccccacg tttttctaaa ttcctgtagg gcgtttttat caaaaatcaa
    13381 gacaagaaga aactcgttca cactcgtttc aaaaaaacaa gaaatctaat ctatacacct
    13441 accgttttcc aaccccctca aagcatacaa attaaaaaca aaattattca taatcttact
    13501 ttcttttaac aaaaacataa aaaccataaa tagacaaatt aactatcaaa ggcaataaac
    13561 agtataaaaa aaccacgaat aaatcttcat caacatctaa aataaaaaag aataaaacaa
    13621 ttaacaaaat actaattaac aaacctaaaa gtggcaaact ttttatatat ttttctaaat
    13681 tttcattcat aaaatagact cctttcaaaa atatgtttat aaatatatta aaataaatat
    13741 tgattttata aagcgcttac ttatacaatt aaaatatctt attatcttgg aggtatcaaa
    13801 tgaaaattat aaaattattt tcaataattt ccttgttcct actggtattt agcgcgaatt
    13861 tttctaatgc ttacgcaaat gaagaacaaa aaagttcttt actagaaaat caaaaagaaa
    13921 aattgaaaag caaatgaaaa aagaaggatt taaaaaaata aagctagaag acaaaaattc
    13981 taaattaaaa tatctagcta cagaagcaaa tgataaaaat gcatatggct acatagctaa
    14041 taacgcttat aaaaatgaaa aaacaaaaga aattgtagtt tctgaaacaa tatatgataa
    14101 ctacaacaaa aaaatcacaa aattcattgc cgaaaaaaga agtatgactg aaaacaaaga
    14161 gggaaaaata cttattaaca aaaattacgt tgaatataag gctgaaaaag ttgataaaaa
    14221 cagaccggta acatatgcag gattcaaatg gaacggcaaa gcattcgctt gtagtatggc
    14281 tggactttat gcatgtgctc actactgtgg agtatgggca atcgtaaatc caatagccgg
    14341 cggtgtatgt gaagcagttt gcggaactgc atttgcagct ggatgctctg taggttgatt
    14401 ttattccaat tgttttattg acgttgagcc tcggaaccct taacaatccc aaaacttgtc
    14461 gaatggtcgg cttaatagct cacgctatgc cgacattcgt ctgcaagttt agttaagggt
    14521 tcttctcaac atcaataaat tttttcggca taaatacgat gttccttatt tatcctcata
    14581 aaaaacaata gctgaaatat ataaccaatt actgtgtgtt tgaatttcta atacatgaat
    14641 atcattcttt aaaaacctat taacttgttt atctaattga cgatgagtaa aagtagcgaa
    14701 agttttaatc ttcatgatat ctctcctttt ataaaaatag caatccttat tacaatatta
    14761 aacactttta ttttggattt taagaggcat tttgaagact tagaggcaaa tcatataggt
    14821 tttgtactta aaaatctata cagtctctta aaacgcaaat atgagccaaa taaatatatg
    14881 gtaatttcac aaacaaaaat ttcagcaaaa ccagtgacta attttttaac actgcccatt
    14941 tacatgcaaa ttaaaaatta gcataaaatc ctttaaaact tccacatgtt tttctaaatt
    15001 cctgcagggc gttttttatc aaaaatcgag aatttttaat ttttctctaa aaactccgta
    15061 agagcataag gagaatttgc tatcattcaa aaatgatagg tctggcaaag ccagaaattc
    15121 caggggtttt aaggtatttt aaagtgatat catacaaagc tgtactgtct tatttttgtg
    15181 acacaatata ttgcgtttgt cttatttttg tgacactaca tacagcattt gtcacaaaaa
    15241 taagacagta cttttttata aaaaatcaac aaaaaagaca ttagtcaaca ctaatgtctt
    15301 aaataataat tttgcttttc gaaattccaa attgcggtaa ttgaatgtgc tttttcttct
    15361 tcgtctgttg ttttatcttc atcacttgca ttaatcaaat taccatcttc gacatcgtct
    15421 aagtttaaaa ttttatgttt ttgtttaagc aatccaccat aacttaacat acgttttcga
    15481 tacaaacctt tttctaaatc acttacaatt tcttgatttt tttcgtcgtc atcagttaaa
    15541 aagtcagatg atttaacgga atattttgat gtctcttcga gtgttataaa atcatttgaa
    15601 ttattgatta aagatattat attgtttcat gtttttacgg cgcatataaa gggcatgtgt
    15661 ttcttcaagt tcagttagaa ttgtttgcat taaataagct tgcattgact tgattgtttc
    15721 cttttggcct ttaactcccc tatcatgtat agctttttta agtcttttta aagaagttaa
    15781 tatttcatcc tcaatgtcct ctaacatgta atgcatatct tcatgccttg aattaaatga
    15841 tttttttgct ttaagaataa cagcctttat gatttctaaa tctctataat catattttaa
    15901 taaataatta gttagttgtt ctgggaattc ttgcaatagc atttctttat catcaaaatt
    15961 atgtgtaaat tgatttgaat gatttgaatg attactaatt tcatttttgt actttatatc
    16021 attcaagtca ttcatatcat tattctcagt atcattaaag tcaatgtcat taaagtcagt
    16081 atcattagtg ttcgattttc gaacttctgg acgttcgatt ttcgaacttc tggacgttcg
    16141 attttcgaac ttctggacgt tcgattttcg aacttccttc tcgccgtaag gttcaacatc
    16201 gttttcttct ttttctattt tgtaaatatc acgttctgtg acaataggtt tcattaaata
    16261 tagaatattt ggtttattta aaccacgtcg tttttgaatg agtagaccat cgttttctaa
    16321 cccttttttt atttttgtta acttttcttt tttacaattt aagatttcca ttagcttttc
    16381 atttgaataa acaaagtaaa tgttaccatc ttcatcaacc cagctatttt taatagataa
    16441 atttaagcga tcacgtaaga tagcataggc tattttcata tcattagtta gatttttata
    16501 attttcactg gtaaagaata ctttagggat ttgataaaat ctttctttgt aattttcttg
    16561 cactgtaaaa tattgatttt gcatgacaaa aaacctcttt ccatatttta gtttggtaag
    16621 aggtaataaa acgtttttat ttagctttac atttatttaa tgatttaggt gcttgcacta
    16681 agatattatt cattatataa tacaagtatc gaaaattata taaataaaca gtttctaaac
    16741 gttttattac caaaccccga ctattaccag tagttggggt ttttgttata ttaagtttat
    16801 tatagcactt taaataaact tataaaaggg aaaatatagc tttatcaagg gtttataaac
    16861 ccttgataaa tatcataaac ctttcataaa cccttgataa aaaggttgat ggatgtttat
    16921 ttttatttat taatcacttt attattaagc attataagct tataatattt tatcaagggt
    16981 ttataaacat tttataaagg gttgatgata tgaaaagtgt gaaaaagttg agtgaagaat
    17041 taggggttag taagcaaacg atttttaata atattaagcg attgaatata gagacaataa
    17101 aacaggaaaa cacttcgttt attaaagaag ataccgatat agaaaaaatc attcaaagag
    17161 taaatgaaaa taaaaagaaa tatggttttg aaagtactac tgaagacaaa caaaaaaaag
    17221 ggtcggataa tattaatttt gaatcgaaaa gcgatgctca aatagtagaa atccttaaaa
    17281 atcagattga tactttaaat aatcaaattg aaaaacaaga aagtcgtcat gaaacaacaa
    17341 ttgaatttta cagaaaagag ttgcaagaaa gatcaaaatt gcttgaaaat cagcaagttc
    17401 tggcattaga gagtaataaa aagattcaaa aattagaaaa tcaattagaa aaagaaaaac
    17461 accttaatta tccctttgat acatctacta acactagaca aaacgttgat gcacaagaaa
    17521 aaacatatac tactaatcct gtaaatatta acagagatca ggaagaaact aaagaaacag
    17581 agattcaata taaggatata tctggaagtc aaagcgacga aagtacacaa ggtgaagaag
    17641 caaaaaaaga agacgttcca gctaatctaa atgacaatga tagtgatata gaagaaaaga
    17701 gtgaagaaac ggaacctaaa aaggggtttt ggagtcgttt gtttggtagc taaaataatt
    17761 gattaggcac taaaagttat aaaattttag tgtcttttat atagtgagaa cttctggtaa
    17821 tcatcgatta tgtaaactaa agtatttcaa ataattaact gtattaatac tctcatcatg
    17881 attgcgttat aaacgttcgt tattgagaca aaatttaata gtactactac acaaaaagag
    17941 agtgcgaatt cgcactctct ttttgtgata aatgaatggt taagaaaata attcatccac
    18001 agttgtatca aacaatcttg ccaacttaaa tgctaatgtc aatgtaggat catatttatt
    18061 gttttctatt gcattaatag tttgcctaga cacttttaat tctttactta aagtttcttg
    18121 agaaattcct ttttgttttc tatattctct aattctattt ttcattaatt taacctttag
    18181 atgtatattt tttatttgta gtatagtaat taaacagcat aagaaatagt gctacaatta
    18241 taaagaaaat ttctggatat tgagaaaacc aagatccttc aatacttggt gacaaacctg
    18301 taaatttaag cactagtgta aataacatac aatatacaat ccaaataaaa cttttagcca
    18361 gtatttcaat aaacatttta cgttgtcttt catcgtatcg atcttgttgt ccttttttat
    18421 ctaatgtttc tgaaggtaaa tatttgttag ttatagccgt ccataaacaa gaaaaaatta
    18481 aaataataat aaaaggaatt aaattcatta taacacctca taaatgtaaa aagtatttga
    18541 catttatgag tgtaaatatt tttgatacaa atgtcaaata ctttttacat tataatatat
    18601 tttaaaacac cttattagta aaacaattac tatatagaaa gctgcgaact cgtactcttt
    18661 tttcttgtat aattattaaa atctcaattc aataatatgt tatggaattt gagacactgt
    18721 gagagacgct catttgcatt gacaatcaat ttatcaagat aatcccttat catgtttaat
    18781 tctataaact gtttgtcttg tgatattaac ttctttcgca atcttactaa tcgctttgcc
    18841 ttcttctaac atttccacca cgcgatgata aataacacgt ttctgtgggt ctttagcatt
    18901 tggtgaataa agtaaagggc gccctttata tacgcctttt tccttcgcaa cttgaatccc
    18961 ttgcgcttgt cgacgtttac tttcatttct ctcttgttct gaaaccattg ctaatatttg
    19021 aatgattaaa tctttcataa acttatccag taatggattg ccaattactt cattcatcat
    19081 aggtaagctg gtaatcatta actgaacgtc tttttctttt aaataattca cagtttcaat
    19141 aatttcatca tagttacgtc ctaaacgatc aatagattcc acaacgaatc gatctcccat
    19201 tctgacaaaa ttgagtgctt cttgaaatac aggtctattt tccactgact ttcccgactg
    19261 tttctctgta aagattttct ccacaccaaa cgtctttaaa ttatccaatt gtctttctaa
    19321 attttgatct atcgatgata ctctcgcata acctataatc attcatcttc actccataat
    19381 aaatatacac cctaatcata cgttttaatt gttataattt caacaattct ttttgtatgg
    19441 ttagggtgta ctcaaagtgt acatatctat aattaaaact tactaaaaat aaatatagat
    19501 tttttctttg taacagaacc gttcatttga aggtcatctc tatcataaat atttaaatta
    19561 actaaaaatt ttaatcatct gtttaatact tatgaaatgt atttacggta ggtattaaaa
    19621 ttgatgaaat ttatataagt gctttcaatg aaaatgaccg tttatttatc ctcctgattt
    19681 aaggagttag aaatttcgaa aacgattctt tccatttgtt gcatttgttc catgtccaga
    19741 tatttaatac attatagaaa accaaagacc atcactaatt aaacgcagtt ttaaaatttc
    19801 atcaggattg ccttcgtctt taaaatgggc ctcttttaat ataagttcta ctctttcata
    19861 cctaactctt tcaatgccat cgtttcatac gccgattctc ctgattccat agcaaactca
    19921 gcgataaaca ttgggaatac tgcattgagt tctattatat gctctttcat tcgtggccat
    19981 atttcacctc cagctttacc gtatgctgtt ataagttgct ctaatccttc gtcgtcgaat
    20041 acacgatggt gtcctataaa gtccattgat gggtcggagt gggttgcttc agtccagtct
    20101 atgagacctg tgacgtttgc ttggttatct accattatat gtcctggatg taagtcccca
    20161 tgtatcatgg tcgcatgtcg aggccatagt tcgtcgtttt ctaaccattg tttccatctg
    20221 ttccataatt catctgatac gccataagtt tctttaactt tattcattct tctttgaaag
    20281 tcatttttta tttcttgtat ggttttgata tttatatgct gaacgttaat gttttcttct
    20341 ggtatgttgt gtaaatctac gagtgtttca gctaatgtgt taataaagtt ttctggtaat
    20401 ggtttgtgtt caatttccca tacataattt tgtatttctg gatctattgt ggctgcgggt
    20461 ttacctgtaa gttttgggta agcaataagg tcttttgcat gtactttcca cttcggtatt
    20521 tcaaatgaaa cattcttctg taagaagtct accgtttgtt tttcgggttt tgttcgttta
    20581 taaacgtcag gtcttcttgg tagtctcaaa acccattcta ctccatgttt atcttttcca
    20641 aatgcaactt gaaaatcaag tcccgattca ttcaatgaga ttgtttgagg ttggatgtgt
    20701 aattgatatt tttctgcaca tttaataatt tcattatgtc gagtcatttt attggatcct
    20761 tatttctatt atatttttct tgtgaacgta ttttttatat tgatataaat gaacctaata
    20821 ttcaatataa attagtgtat agtttttaag ttatatcatg aagagattgt cctgttaatt
    20881 cccatttttt atctgataca tgtttaacaa accttgtatc atgtgatgta aacaaaatga
    20941 ttccaggata tttattcata aacatttcta atgcttctaa tgttttaata tctaaaaaat
    21001 tagttggttc atccaaaatt aacatattcg ctttcgttga aaataatact gctaacgata
    21061 atttcgttct ttccccacca ctcaaaacat tacaagaacg atcaagtgct tcatttaaac
    21121 ccaagttatt taaaatagct ctactgaatg attctgatga atccgtttca tccattaaat
    21181 attgcaataa tgaaacgtca cgcatgtctt cataagcaag ttgacgatag tatgccattt
    21241 gcactttagg agaacaatca attccctcta tttggtggta aatagcttca agtaaagttg
    21301 tcttacctac accatttgca cctacgagcg ctatattttt gccatatggt atttggaatc
    21361 gtacttgtgt tagcagtttt tgacttcctt taaccaatgt tagattttgt gcaatgattg
    21421 gataattatt atggatatca taaattttat tttgtgggaa attgaattca tgataacttt
    21481 gtggtttttc aacttcttcc aaatgttcca ttcttttttc aatatgctta gcttgttttt
    21541 gagcagcctt ctcaaccgtg cctttttgtt ttgatgcact taaacgatct ggtgctatac
    21601 ttttgttttt ttgttttgat gatgcttgtg ccatttgttg cgcttgattt cgtttagctt
    21661 tactggcttg ggacaatctt tgtttttcac ttatatactg ttcatattga cgttgttgtt
    21721 ctaactgttc ttgttcatat tgattttgat actgtgtgta attaccttta aacactctta
    21781 ttgtgccatc ttcttgtata tcccaaattg tgtcagcaat ttggtctata agtgctctat
    21841 catgacttac tataattaaa gtaccatagt aatattttaa aatatttttc agataatctt
    21901 taccaatttt atccaagtga tttgtaggtt catctaaaag taatatcgga ctataatttg
    21961 atatgacatt agctaattta tattttgctt tttcaccacc actcatactg tcggttgtat
    22021 gcataggtat atggagttca ctcattaaac taccgtctaa cgtgttaaaa tcattttcca
    22081 catccatgtt aagctgttca aaatattgaa tttcgccaac cgtttcaact gttccagatt
    22141 ctggttttgt tttttgagca atcatattta gtaatgtggt tttgccagta ccattacccc
    22201 caataagtgc tattttttca aattggtaag cgtaaagatg accgatgtta agtgatcgta
    22261 aatctgtcaa tttatgattg atttggttaa atttaattgt atattgttcc atatttatac
    22321 actccttgta tatttaaagg acgtgtacgc aaaaaaatga gacaggctac tcccgtctca
    22381 ttcacattac actttcaaac acttaaaaat ttattatgat gttttagtat ttgaaagcgt
    22441 ttattattcc tatcgaagga taaaaaatga cataagtcat cctatgagtg tgtattgcgg
    22501 acaagccttt ttgaattaat ttagttttgt attcaaaaag gtttatttga gtctcataga
    22561 agctgtcatt ttaatcctcc ttcatcgata aaatagtaat gttaatataa cattttgttg
    22621 gtttttttac aatatatctc taagtagaaa gattatataa caaaagtata aaaatacaat
    22681 tttagattga ttatacatct ccttaattta gagtgtactc ataaaatacg gttctgttgc
    22741 aaagttgaat ttataatata attttaacaa aaaggagtct tctgtatgaa ctatttcaga
    22801 tataaacaat ttaacaagga tgttatcact gtagccgttg gctactatct aagatatgca
    22861 ttgagctatc gtgatatatc tgaaatatta agagaacgtg gtgtaaacgt tcatcattca
    22921 acgatctacc gttgggttca agaatatgcc ccaattttat atcaaatttg gaagaaaaag
    22981 cataaaaaag cttattacaa atggcgtatt gatgagacgt atatcaaaat aaaaggaaaa
    23041 tggagctatt tatatcgtgc cattgataca gagggacata cattagatat ttggttgcgt
    23101 aagcaacgag ataatcattc agcatatgcg tttatcaaac gtctcattaa acaatttggt
    23161 aagcctcaaa aggtagttac agatcaggca ccttcaacga aggcagcaat ggctaaaata
    23221 attaaagctt ttaaacttaa acctgactgt cattgtacat cgaaatatct gaataacctc
    23281 attgagcaag atcaccgtca tattaaagta agaaagacaa gatatcaaag tatcaatacg
    23341 gcaaagaata ctttaaaagg tattgaatgt atttacgctc tatataaaaa gaaccgtagg
    23401 tctcttcaga tctacggatt ttccccatgc cacgaaatta gcatcatgct agcaagttaa
    23461 acgaacactg acatgatata ttagtgatta gctatatttt ttactttgca acagaaccag
    23521 ccatttaata tgactgttac aattactaag attcaagcac tattacgccg cacgtatgat
    23581 ttcaccactc aagttaataa tttaacagta gatgattgcg agttactact tgatgcagca
    23641 aagcttaaat ttaatgaaga aaccatagac ctgacacaca ctgaattgca aatcatgcat
    23701 agcttattcc agaacaaggg caaattcgtc agtcgtaatg cgttaatcga aaaatgctgg
    23761 gaatcagaac acttcattga tgacaatacg cttgctgtca acattacacg tttacgcaaa
    23821 aagctacaaa aactaggact tacagatttt atcgaaacga agaaaaatgt cggatatcgt
    23881 gtaggtgacg tatgaatttc ttgaaatcaa tccaacgtga aatttatatt gtcatcctta
    23941 cttgtgcttt attctacttt atattattca tgtataatgt gccgatgcaa gcatatatga
    24001 ttggtctagg tattgtattg tttgtttcaa tgatttactg gggtatccat tacatgaact
    24061 ttaaaaaaga ataaacacta caggaacaga acgaagattt aagaatcgaa aaccataaac
    24121 ttcgtaatga ctttattaac taccaaagtg agttagagtc atatttttta atgtgggtgc
    24181 atcaaatcaa gacaccgatt acagcatcaa agttactgct tgaagatcct gatgaacacg
    24241 tgatttctaa cgtgcgtaat gaagtcttac aaattgataa ttacacgaat cttgcactga
    24301 actatttgaa actcatgaac caaaagacat acatggtctt tatggaagtg agtgtagatg
    24361 aattaattcg accactgatt aaacgttatg cgatacagtt tattcatcat caaacaaagt
    24421 tgcattatga gaaaagtgaa gcggttatat taacagatgc caaatgggca tcaattatga
    24481 ttgagcaaat attaaacaat gcattaaaat atgcacgtgg caaagatgtg tggattacgt
    24541 ttgacgaaaa tacaaagaaa ttatcaatcc gagataacgg tatcggcatt aatgcgagtg
    24601 atttaccgaa aatctttgat aaaggtttct cgggctataa cggtagaata agtgagaaat
    24661 caagcggtat tggtttatat attgtcagca caatctcaaa gcgcttaggc cataaagtaa
    24721 gtgctacatc tacattaaac gatggttcaa tattcaccat tcaatttaaa taactccaat
    24781 ctttcatttt tgtaagatta gcggctgttt ttgtaagaat agataaaggc agccttttct
    24841 aatcgcgcgt aagataaagg taacaacaaa ctaagaaagg tgccagaggt gaaaaatttg
    24901 aataatataa ttgaaataaa taacttaaca aagcaatatg gaagtcagat agcagttaat
    24961 aatttgagta taactgttga aagtggacaa atttatggtt ttttaggaag aaatggtgca
    25021 ggcaaaacaa ctactataag aatgctttta ggcttaatta aacctacgaa aggtaatatt
    25081 aaaatatttg aaaaagagtt cgaaagtaat aaaactgaaa ttttaaaaaa tattggtgct
    25141 atggttgaaa cgccaggttt ttatagtaat ttgacagcta aagagaactt aactataaat
    25201 gctaaaatat taggtataca aaaagaaaat gcaattgaag aagtgttaga aatagtagga
    25261 ctagcttctg aaaaagtaaa attgtttaaa aattattctt taggtatgaa gcaacgttta
    25321 gggattgcga gagctttatt gcacaatccc gaattattga tacttgatga gccgacgaat
    25381 ggattagatc ctattggcat aaaagaaatt agaaagttga ttaaggatct ggctcaatct
    25441 agaaatataa ccattttaat ttcaagtcat atattgtcag aaatagagca gttagtagac
    25501 aaggtgggta ttattcataa cggagttttg ttagaagaaa ttatgtatga agatttaaaa
    25561 aaaaagaaca gacaatttat aagtatatca gtatcagatg aagaaaaagt tgcatgtttg
    25621 ttggaaacta acttcggaat ttatgactat aaaattaaag aaaatggcga atttaaaatt
    25681 tattcacata ttgatagaca acaagaaatt aatagattat tagtattaaa caatattgat
    25741 gttttccaga tgagagtgat agaagataat ctagaaactt atttcgaaga cttagtagga
    25801 ggtggcacaa ttggataatc tactccgtac agaatttatt aagttaaaaa gatcatatat
    25861 gtttctaata agtattttag gtacatgcgt agcacctttt atggtggttg tagcttcttt
    25921 tattagtatg cggacgaaag taccgactcc taatattgta tttaaacagt tatttgaaga
    25981 agtcagttta tatcatatgc taattattgg acctcctcta tatggggtta taatagccta
    26041 tttgtttgga agagaatata tagaagatac tttaaaaaac ttattaatta tacctatatc
    26101 tagagaaagt tttttagtaa gtaaaataat attattattc ttgtggattc aaacactatc
    26161 tgttattgca tggttgctaa ctttaatgct aggtatgcta ttgcattttc aagggttaag
    26221 ccagagttta ataattgatt cattctttac atttgttatt ggcggagtgt tattatggat
    26281 attatctcca ccaataatta ttttgtcgat atattttaaa aattatgttc ccacaattgt
    26341 tttaaccata ataattactt tgataaattt aatgactgct aattctgaac atagaggatt
    26401 atttccttgg gctgcagttg gagacatatc tagaggaaca ttacctaata cttatccatt
    26461 tctattatct ttaattatca taattgttac atctatattc agtgtaatta tattattctc
    26521 atactttaaa aaaactgata taagttaaaa ggaggagaaa aatgggtttt atagagcaga
    26581 ttaaagcatt tattttaggt gtagttgaag ggttgacaga atttgctcca gtatcatcaa
    26641 caggtcatat gattattgtt gatgatatgt ggttaaacac tgctgacgat ttaggaagtg
    26701 cgtctgcaac tacttttaag gtggtaatac agttaggagg ttctgttgca aagttgaatt
    26761 tataatataa ttttaacaaa aaggagtctt ctgtatgaac tatttcagat ataaacaatt
    26821 taacaaggat gttatcactg tagccgttgg ctactatcta agatatgcat tgagctatcg
    26881 tgatatatct gaaatattaa gagaacgtgg tgtaaacgtt catcattcaa cgatctaccg
    26941 ttgggttcaa gaatatgccc caattttata tcaaatttgg aagaaaaagc ataaaaaagc
    27001 ttat
//
