LOCUS       NZ_CP149310             6647 bp    DNA     circular CON 05-APR-2024
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium strain
            Z1323SSL0041 plasmid pZ1323SSL0041-4, complete sequence.
ACCESSION   NZ_CP149310
VERSION     NZ_CP149310.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN40439970
            Assembly: GCF_037856515.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium (Salmonella
            typhimurium)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6647)
  AUTHORS   Chae,J.-C., Oh,J.Y., Jeong,J.H. and Kwak,S.M.
  TITLE     Complete genome sequence of Salmonella enterica subsp. enterica
            serovar Typhimurium isolated from humans and pigs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6647)
  AUTHORS   Chae,J.-C., Oh,J.Y., Jeong,J.H. and Kwak,S.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAR-2024) Division of biotechnology, Jeonbuk National
            University, kobongro, Iksan 54596, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 83X
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_037856515.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 21:21:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,949
            CDSs (total)                      :: 4,826
            Genes (coding)                    :: 4,693
            CDSs (with protein)               :: 4,693
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 16
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 39 of 133
            Pseudo Genes (incomplete)         :: 102 of 133
            Pseudo Genes (internal stop)      :: 21 of 133
            Pseudo Genes (multiple problems)  :: 27 of 133
            Pseudo Genes (short protein)      :: 1 of 133
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP149310.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6647
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium"
                     /mol_type="genomic DNA"
                     /strain="Z1323SSL0041"
                     /serovar="Typhimurium"
                     /host="Pig"
                     /sub_species="enterica"
                     /db_xref="taxon:90371"
                     /plasmid="pZ1323SSL0041-4"
                     /geo_loc_name="South Korea"
                     /collection_date="2023-03-24"
     gene            complement(461..652)
                     /locus_tag="WI404_RS24665"
                     /old_locus_tag="WI404_24665"
     CDS             complement(461..652)
                     /locus_tag="WI404_RS24665"
                     /old_locus_tag="WI404_24665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165985.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDADEQADICESLHDHA
                     DELYRSCLARFGDDGENL"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            716..1039
                     /locus_tag="WI404_RS24670"
                     /old_locus_tag="WI404_24670"
     CDS             716..1039
                     /locus_tag="WI404_RS24670"
                     /old_locus_tag="WI404_24670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_000955999.1"
                     /translation="MLTIRVTDDEHARLLERCEGKQLAVWMRRVCLGEPVARSGKLPTL
                     APPLLRQLAAIGNNLNQTARKVNSGQWSSGDRVQVVAALMAIGDELRRLRLAVREQGAR
                     DDS"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            1248..>1679
                     /locus_tag="WI404_RS24675"
                     /old_locus_tag="WI404_24675"
                     /pseudo=""
     CDS             1248..>1679
                     /locus_tag="WI404_RS24675"
                     /old_locus_tag="WI404_24675"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            1717..2235
                     /locus_tag="WI404_RS24680"
                     /old_locus_tag="WI404_24680"
     CDS             1717..2235
                     /locus_tag="WI404_RS24680"
                     /old_locus_tag="WI404_24680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001447511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_000067500.1"
                     /translation="MSNLLQTGAEFEKKLKERAESTEKMLNNEFRRLGESVSEAVTSNE
                     TKIRDAIALFTASTEESLEKHREGVKEAMMQHRRDVLKLAGNTGMMLLGIVFLLFTASG
                     GTLWYLGGRIQANLEEIRKQEETLQKLNAKTWGVEFVQDGNRKFLVLPYGKSAEVIPFQ
                     GKEWVHLKE"
                     /name="MbeB family mobilization protein"
     gene            2242..2475
                     /locus_tag="WI404_RS24685"
                     /old_locus_tag="WI404_24685"
     CDS             2242..2475
                     /locus_tag="WI404_RS24685"
                     /old_locus_tag="WI404_24685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_000137445.1"
                     /translation="MTELETHLLNALEQLQQDYMQRLSEWESAFVELQKMFSLTQRDNA
                     MLNERVMQLSQQVQHLSEQTERLSQLYSENWR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(2793..3212)
                     /locus_tag="WI404_RS24690"
                     /old_locus_tag="WI404_24690"
     CDS             complement(2793..3212)
                     /locus_tag="WI404_RS24690"
                     /old_locus_tag="WI404_24690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254967.1"
                     /translation="MRRTGNKLCLIAMITATVALTACTPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLRGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            complement(3293..3730)
                     /locus_tag="WI404_RS24695"
                     /old_locus_tag="WI404_24695"
     CDS             complement(3293..3730)
                     /locus_tag="WI404_RS24695"
                     /old_locus_tag="WI404_24695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001405929.1"
                     /translation="MGHCHFMAWHTLRDALKMTGRSRSQFYRDMRAGLVSYRTGRDGRR
                     EFETSELIRAYGELKQNETPERHSEGHAENPHDQQTERILRELNELKQCLTLMLEDKQA
                     QDMDRRRQEAEREQLQNEIAQLRQALELEKKRGFWSRLFGR"
                     /name="hypothetical protein"
     gene            3990..5558
                     /gene="cea"
                     /locus_tag="WI404_RS24700"
                     /old_locus_tag="WI404_24700"
     CDS             3990..5558
                     /gene="cea"
                     /locus_tag="WI404_RS24700"
                     /old_locus_tag="WI404_24700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pore-forming bacteriocin colicin E1"
                     /protein_id="WP_000447006.1"
                     /translation="METAVAYYKDGVPYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKS
                     ESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRH
                     NASRTPSATELAHANNAAMQAEAERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIERE
                     KAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSS
                     IHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAG
                     KIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNL
                     LNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDV
                     LNKKFSKADRDAIFNALASVKYDDWAKHLDQFAKYLKITGHVSFGYDVVSDILKIKDTG
                     DWKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYIDKNKLNTIN
                     EVLGI"
                     /name="cea"
     gene            complement(5555..5896)
                     /locus_tag="WI404_RS24705"
                     /old_locus_tag="WI404_24705"
     CDS             complement(5555..5896)
                     /locus_tag="WI404_RS24705"
                     /old_locus_tag="WI404_24705"
                     /inference="COORDINATES: protein motif:HMM:NF015489.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E1 immunity protein"
                     /protein_id="WP_000058760.1"
                     /translation="MSLRYYIKNILFGLYCTLIYIYLITKNSEGYYFLVSDKMLYAIVI
                     STILCPYSKYAIEYIAFNFIKKDFFERRKNLNNAPVAKLNLFMLYNLLCLVLAIPFGLL
                     GLFISIKNN"
                     /name="colicin E1 immunity protein"
     gene            5944..6081
                     /locus_tag="WI404_RS24710"
                     /old_locus_tag="WI404_24710"
     CDS             5944..6081
                     /locus_tag="WI404_RS24710"
                     /old_locus_tag="WI404_24710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405930.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_001405930.1"
                     /translation="MRKRFFVGIFAINLLVGCQANYIRDVQGGTIAPSSSSKLTGIAVQ
                     "
                     /name="colicin release lysis protein"
     gene            complement(6280..6438)
                     /locus_tag="WI404_RS24715"
                     /old_locus_tag="WI404_24715"
     CDS             complement(6280..6438)
                     /locus_tag="WI404_RS24715"
                     /old_locus_tag="WI404_24715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071531517.1"
                     /translation="MHEPPVQPDRCALSGNYRLESNPVRHALTPLAAATGNRISRAMMA
                     QTVLQSS"
                     /name="replication initiation protein"
     Typing          289..376
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="6.86e-39"
     Typing          complement(2..275)
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.841"
                     /coverage="99.0"
                     /evalue="1.9199999999999999e-112"
     Typing          complement(6330..6647)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="97.179"
                     /coverage="100.0"
                     /evalue="2.17e-150"
     Typing          1030..2579
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.473"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtcgattttt gtgatgctcg tcaggggggc ggagcctatg gaaaaacgcc tgctacgtgg
       61 ccttcttcct gttcctggtc ttttgctcac atgttctttc cggccttatc ccctgattct
      121 gtggataact gtgttaccgt ttttgtgtga gtcagtaccg ctcgccgcag tcgaacgacc
      181 gagcgtagcg agtcagtgag cgaggaagcg gaaaagcgcc tggacgtgca ttttctcctt
      241 acgcatctgt gcggcatttc acacccggca tggcgtactt ttcatacaat ccgcactgat
      301 gccgcatggt taagccagta tacactccgc tatcgctacg tgactgggtc agggctgcgc
      361 cccgacaccc gctaaaacct gctgacgcgc cctgacgggc ttgtcagctc ccggcatccg
      421 ctcacagaca agctgtgacc gtctccggga gctgcatgtg tcagaggttt tcaccgtcat
      481 ccccgaaacg tgcgaggcag ctgcggtaaa gctcatcggc gtggtcgtga agcgattcac
      541 aaatatcggc ctgttcatct gcgtccagtt cgttgagctt ctccagcagc gttaatgtct
      601 ggcttctgat aaagcgggcc atgttaaggg cggttttttc ctgtttagtc actgatgcct
      661 ccgtgtaagg gggatttctg ttcatggggt aatgataccg atgaaacgcg agaggatgct
      721 cacaatacgg gttactgatg atgaacatgc ccggttactt gaacgctgtg agggtaaaca
      781 actggcggta tggatgcggc gggtctgcct gggggagccg gttgcccgtt ccggaaaact
      841 gccgacactg gcaccgccgt tactgcgtca gctggccgcc atcggaaata acctgaatca
      901 gacagcccgt aaggtgaaca gcgggcagtg gtcttccggt gaccgggttc aggtggtggc
      961 cgcactgatg gccatcgggg atgagctgcg ccggctgcgt ctggctgtca gggaacaggg
     1021 ggcgcgggat gatagttaaa tttcatgcca ggggaaaagg tggtggcagt ggtccggttg
     1081 attacctgct ggggagggag cgtaaccgcg aaggcgcaac ggtgcttcag ggtaatccgg
     1141 aagaagtccg ggaactcatc gatgccacgc catttgcgaa gaaatacacg tccggtgttc
     1201 tgtcgttcgc ggagaaggag ctgccgccgg gaggacgtga aaaagtgatg gcgagctttg
     1261 agcgtgtact gatgcccggt ctcgaaaaaa atcagtacag catcctgtgg gtggagcacc
     1321 aggacaaggg acggcttgag ctgaattttg tcattccgaa catggagcta cagaccggaa
     1381 aacgcctcca gccgtactac gaccgcgcag acaggcctag aattgatgcc tggcagacgc
     1441 tggtgaatca ccattacggg ctgcatgacc cgaacgcccc ggagaaccgc aggacgctga
     1501 cactccctga taacctgcct gaaacgaaac aggcgcttgc tgagggcgtc acgcgaggta
     1561 tagatgcact ttaccatgcc ggagagataa aaggccgtca ggatgtgatt caggcgctca
     1621 ctgaggcggg gctggaagtg gtcagggtga cgcgaagcag tatcagcatt gcagatccga
     1681 acggcgggaa gaatatcagg ctgaaaggag cattttatga gcaatctttt gcagacgggc
     1741 gcggagttcg agaaaaagct gaaagagaga gccgaatcta cagagaaaat gctgaacaac
     1801 gagttcagga ggctcggcga atctgtaagc gaggctgtga catcaaacga gacgaaaatc
     1861 agagacgcta tagccctgtt cacagcctcg acagaggaat cgctggaaaa acaccgggaa
     1921 ggggtgaaag aggcgatgat gcagcacagg agggacgtgt taaagctggc agggaatacg
     1981 ggcatgatgt tactggggat agtctttctc ctgtttaccg cgagtggcgg gacgctctgg
     2041 tatcttggag ggaggataca ggcgaacctg gaagaaatca ggaagcagga agagacattg
     2101 cagaaactga acgcgaagac atggggcgtg gagtttgtgc aggacgggaa caggaaattc
     2161 cttgtccttc cgtacgggaa atcagcggag gtgattccct ttcaggggaa agagtgggta
     2221 catctgaagg agtgacacag agtgacagag ctggaaacac atttgctgaa cgccttagag
     2281 cagctgcaac aggactatat gcagcggctg agcgaatggg agagcgcctt cgtggaattg
     2341 cagaagatgt tttcgcttac gcaacgggac aacgcgatgc tgaacgagcg ggtcatgcag
     2401 ttgagtcagc aggtgcagca cttgagcgag cagacagaac gcttgagcca gttatacagc
     2461 gagaactgga gataagagag gaacggctga tacaggagcg cgaacatgtg ttatccctgg
     2521 aacgggagcg tcagccggaa atacaggaac gcacgctgga tggcccttcg ctgggatggt
     2581 gaaaccatga aaaatggcag cttcagtgga ttaagtgggg gtaatgtggc ctgtaccctc
     2641 tggttgcata ggtattcata cggttaaaat ttatcaggcg cgatcgcggc agtttttcgg
     2701 gtggtttgtt gccattttta cctgtctgct gccgtgatcg cgctgaacgc gttttagcgg
     2761 tgcgtacaat taagggatta tggtaaatcc acttactgtc tgccctcgta gccatcgaga
     2821 taaaccgcag aaatcgtgtc agccagcagc ctggattttt tcggggtaag gtctttgctg
     2881 cggtaatcag tacccgcaaa ttgagttgtg ccccggagtg agtttaaaaa ttcctggctg
     2941 tgaaactgct gaatgcgttg ttgcacatca ctccgtgatt ttcctgtcgc tttatcttta
     3001 gctcccatat cccagaactg ccgaaaaaaa ggcaccatca ttcgtgttgt gtcggctttt
     3061 tgggtggaaa agttgggatc aaaaccgtca tcagaagcat atacgtaatg ccgggtatgt
     3121 tgttccacgc tgccctttgg ggtacaggct gtgagagcta ctgttgctgt tatcatggcg
     3181 ataagacaaa gtttgtttcc ggtacgtctc atgagtgtct ccctacctta aagtatttat
     3241 tctcggtgag ttattatccg aagactattt tatcatcagt ctctgacagc gttcagcgac
     3301 cgaacaacct ggaccagaat ccccgtttct tttccagttc cagtgcctgc ctgagctggg
     3361 ctatctcatt ttgtagctgt tcccgttctg cttcctggcg tctgcgatcc atatcctgtg
     3421 cctgtttatc ctcaagcatc agcgtcaggc attgtttcag ctcattcagc tcccggagaa
     3481 tgcgttctgt ctgctgatca tgtggatttt ctgcatgtcc ctcactgtgc ctttctggtg
     3541 tctcattctg ctttaattcg ccgtatgccc ggatcagttc actggtttca aactcccgtc
     3601 gtccgtccct gccggtacgg taactgacaa ggcctgcgcg catatcacgg taaaactgtg
     3661 aacgcgatct gcctgtcatt tttagtgcgt cccggagtgt gtgccatgcc ataaagtgac
     3721 agtgtcccat agatgtctca tctcatagtt tcagtaaaac ataatgaggt ctgagaacgg
     3781 taatgtttgt gctggttttt gtggcatcgg gcgagaatag cgcgtggtgt gaaagactgt
     3841 ttttttgatc gttttcacaa aaatggaagt ccacagtctt gacagggaaa atgcagcggc
     3901 gtagctttta tgctgtatat aaaaccagtg gttatatgta cagtatttat ttttaactta
     3961 ttgttttaaa agtcaaagag gattttataa tggaaaccgc ggtagcgtac tataaagatg
     4021 gtgttcctta tgatgataag ggacaggtaa ttattactct tttgaatggt actcctgacg
     4081 ggagtggctc tggcggcgga ggtggaaaag gaggcagtaa aagtgaaagt tctgcagcta
     4141 ttcatgcaac tgctaaatgg tctactgctc aattaaagaa aacacaggca gagcaggctg
     4201 cccgggcaaa agctgcagcg gaagcacagg cgaaagcaaa ggcaaacagg gatgcgctga
     4261 ctcagcgcct gaaggatatc gtgaatgagg ctcttcgtca caatgcctca cgtacgcctt
     4321 cagcaacaga gcttgctcat gctaataatg cagctatgca ggcggaagca gagcgtttgc
     4381 gccttgcgaa agcagaagaa aaagcccgta aagaagcgga agcagcagaa aaggcttttc
     4441 aggaagcaga acaacgacgt aaagagattg aacgggagaa ggctgaaaca gaacgccagt
     4501 tgaaactggc tgaagctgaa gagaaacgac tggctgcatt gagtgaagaa gctaaagctg
     4561 ttgagatcgc ccaaaaaaaa ctttctgctg cacaatctga agtggtgaaa atggatggag
     4621 agattaagac tctcaattct cgtttaagct ccagtatcca tgcccgtgat gcagaaatga
     4681 aaacgctcgc tggaaaacga aatgaactgg ctcaggcatc cgctaaatat aaagaactgg
     4741 atgagctggt caaaaaacta tcaccaagag ccaatgatcc gcttcagaac cgtccttttt
     4801 ttgaagcaac cagacgacgg gttggggccg gtaagattag agaagaaaaa caaaaacagg
     4861 taacagcatc agaaacacgt attaaccgga taaatgctga tataactcag atccagaagg
     4921 ctatttctca ggtcagtaat aatcgtaatg ccggtatcgc tcgtgttcat gaagctgaag
     4981 aaaatttgaa aaaagcacag aataatctcc ttaattcaca gattaaggat gctgttgatg
     5041 caacagttag cttttatcaa acgctgactg aaaaatatgg tgaaaaatat tcgaaaatgg
     5101 cacaggaact tgctgataag tctaaaggta agaaaatcgg caatgtgaat gaagctctcg
     5161 ctgcttttga aaaatacaag gatgttttaa ataagaaatt cagcaaagcc gatcgtgatg
     5221 ctatttttaa tgcgttggca tcggtgaagt atgatgactg ggctaaacat ttagatcagt
     5281 ttgccaagta cttgaagatt acggggcatg tttcttttgg atatgatgtg gtatctgata
     5341 tcctaaaaat taaggataca ggtgactgga agccactatt tcttacatta gagaagaaag
     5401 ctgcagatgc aggggtgagt tatgttgttg ctttactttt tagcttgctt gctggaacta
     5461 cattaggtat ttggggtatt gctattgtta caggaattct atgctcctat attgataaga
     5521 ataaacttaa tactataaat gaggtgttag ggatttaatt attctttatt gatataaaaa
     5581 gtcctagcaa tccaaatggg attgctagga ccaaacaaag tagattatat agcataaata
     5641 ggtttaattt tgctacgggg gcgttattta ggttttttct tctttcgaaa aaatctttct
     5701 ttatgaagtt aaaagctatg tattcaatag catattttga atatggacat agaatagtgc
     5761 ttatcactat tgcatatagc atcttatctg acacaaggaa ataataccct tcgctgtttt
     5821 ttgttataag gtatatatat ataagtgtgc agtacaggcc aaataaaata ttttttatgt
     5881 agtatcttaa gctcataaat taaacctcgc catatattct tttcatttta taaggatcga
     5941 gttatgagga aaagattttt tgtgggaata ttcgcgataa acctccttgt tggatgtcag
     6001 gctaactata tacgtgatgt tcagggaggg accatcgcac catcctcctc ttctaaactg
     6061 acggggatcg cggttcagta gaaaagatca aaggatcttc ttgagatcct ttttttctgc
     6121 gcgtaatctg ctgcttgcaa acaaaaaaac caccgctacc aacggtggtt tgtttgccgg
     6181 atcaagagct accaactctt tttccgaagg taactggctt cagcagagcg cagataccaa
     6241 atactgtcct tctagtgtag ccgtagtcgg gccactactt caagaactct gtagcaccgt
     6301 ttgtgccatc atcgctctgc taatccggtt accagtggct gctgccagtg gcgttaaggc
     6361 gtgccttacc gggttggact caagacgata gttaccggat aaggcgcagc ggtcgggctg
     6421 aacggggggt tcgtgcacac agcccagctt ggagcgaacg acctacaccg aactgagata
     6481 ccaacagcgt gagctatgag aaagcgccac gcttcccgaa gggagaaagg cggacaggta
     6541 tccggtaagc ggcagggtcg gaacaggaga gcgcacgagg gagcttccag ggggaaacgc
     6601 ctggtatctt tatagtcctg tcgggtttcg ccacctctga cttgagc
//
