LOCUS       NZ_CP149249            10926 bp    DNA     circular CON 23-APR-2024
DEFINITION  Salmonella enterica subsp. enterica serovar 4,[5],12:i:- strain
            Z1322HSL0048 plasmid pZ1322HSL0048-4, complete sequence.
ACCESSION   NZ_CP149249
VERSION     NZ_CP149249.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN40440211
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar 4,[5],12:i:-
  ORGANISM  Salmonella enterica subsp. enterica serovar 4,[5],12:i:-
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10926)
  AUTHORS   Chae,J.-C., Oh,J.Y., Jeong,J.H. and Kwak,S.M.
  TITLE     Complete genome sequence of Salmonella enterica subsp. enterica
            serovar 4,[5],12:i:- isolated from humans and pigs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10926)
  AUTHORS   Chae,J.-C., Oh,J.Y., Jeong,J.H. and Kwak,S.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAR-2024) Division of biotechnology, Jeonbuk National
            University, kobongro, Iksan 54596, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method              :: Unicycler v. v0.4.9
            Genome Representation        :: Full
            Expected Final Version       :: Yes
            Genome Coverage              :: 111X
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Name              :: GCF_038397195.1-RS_2024_04_23
            Annotation Date              :: 04/23/2024 10:48:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.7
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 12
            CDSs (total)                 :: 12
            Genes (coding)               :: 12
            CDSs (with protein)          :: 12
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP149249.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..10926
                     /organism="Salmonella enterica subsp. enterica serovar
                     4,[5],12:i:-"
                     /mol_type="genomic DNA"
                     /strain="Z1322HSL0048"
                     /serovar="4,[5],12:i:-"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:440524"
                     /plasmid="pZ1322HSL0048-4"
                     /geo_loc_name="South Korea"
                     /collection_date="2022-09-05"
     gene            81..269
                     /locus_tag="WIY66_RS00005"
     CDS             81..269
                     /locus_tag="WIY66_RS00005"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000547462.1"
                     /translation="MHIIKPQLTKLKVVFVSKGACLFISNRQKGYVDDPKRDISININN
                     SILVGLRFKLAMIKDKM"
                     /name="hypothetical protein"
     gene            761..1780
                     /locus_tag="WIY66_RS00010"
                     /old_locus_tag="WIY66_25200"
     CDS             761..1780
                     /locus_tag="WIY66_RS00010"
                     /old_locus_tag="WIY66_25200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001271364.1"
                     /translation="MSAALQYFEENLPHRPYHTDDLAFGLRISGKGRALLARYIQQNQP
                     HAQFWLVFDVDREGAAIDWSDRNAPAPNITVKNPVNGHAHLLYALNIAVRTAPDASVKA
                     LKYAAAVERSLCEKLCADVNYSGLICKNPFHLEWQVMEWREDAYTLDELADYLDLSASE
                     RRSIDKHYGMGRNCHLFEMTRKWAYRAIRQGWPAFSQWLEAVIQRVEMYNASLPVPLSL
                     AECRAIGKSIAKYTHRNFTPETFAQYVADTHTPEIQAARGRKGGKANSSENQSDKGKKS
                     AAVRWTANDDKRRRALDMYILGASTEDIAVAVGVSSRTIRRWMDNSGEWLTKKQIIKC"
                     /name="replication initiation protein"
     gene            complement(2041..2439)
                     /locus_tag="WIY66_RS00015"
                     /old_locus_tag="WIY66_25205"
     CDS             complement(2041..2439)
                     /locus_tag="WIY66_RS00015"
                     /old_locus_tag="WIY66_25205"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001222916.1"
                     /translation="MRISNIEWLKKRIGFIRKLGEQTARQRQIIDLLDNEAGLTEQERK
                     LLHVLATAEKNDLQAQESERKQAVQKRIEGKKQRRERNHRLFLAAGLLIEAGLVDTKTG
                     ELCYKKDRILQALKEIKYDLETSPNPDA"
                     /name="hypothetical protein"
     gene            2616..3542
                     /locus_tag="WIY66_RS00020"
                     /old_locus_tag="WIY66_25210"
     CDS             2616..3542
                     /locus_tag="WIY66_RS00020"
                     /old_locus_tag="WIY66_25210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_001736644.1"
                     /translation="MATYHLSVKFGGKGQAANHADYIERKEKYRDRQDLEYSAHGNMPE
                     WARDNPSHFWQAADQFERANGSTYRELEIALPRELTPEQRLELVQDFVRQEAGERHAWS
                     FAIHNPKASIEGGEQPHAHIMMSQRVNDGIERTPEQYFRRYNARYPERGGAKKDSGSLT
                     PTQQKEQLRELRKRWEVKHNEHMRKNGFERGFIDCRTLKEQGIERRPEVHLGFEAAGRL
                     DDAQRHDIMQKRSEPDYSRHLEQARTVGHDIMEWLDTPVKQHELVRRLQHDVAREHGFD
                     MRDRVSRQDRTEPERVKSPSRGFSMGF"
                     /name="MobA/MobL family protein"
     gene            3545..4078
                     /locus_tag="WIY66_RS00025"
                     /old_locus_tag="WIY66_25215"
     CDS             3545..4078
                     /locus_tag="WIY66_RS00025"
                     /old_locus_tag="WIY66_25215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000168774.1"
                     /translation="MASTEEKLLTLLLSVEHLQHTAMEQQKAVADSLAVARETLRGYRD
                     ISDGVAKQVRDEVRNEVQNLDVAGLIGERISQDFQRLEESVANMKANADALNRDIATIH
                     SNIVQEYNTLKGYSWKWLGGVSVAFLVMFCVLGWGMKTMLDRNYNATAAVYQKVVILED
                     KLAEKPVTGKNRKN"
                     /name="hypothetical protein"
     gene            4299..5423
                     /locus_tag="WIY66_RS00030"
                     /old_locus_tag="WIY66_25220"
     CDS             4299..5423
                     /locus_tag="WIY66_RS00030"
                     /old_locus_tag="WIY66_25220"
                     /inference="COORDINATES: protein motif:HMM:NF013211.4"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA];
                     GO:0050829 - defense response to Gram-negative bacterium
                     [Evidence IEA]; GO:0031640 - killing of cells of another
                     organism [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like pore-forming protein"
                     /protein_id="WP_021529456.1"
                     /translation="MSGGDGRGPGNTGLGHNGGKPSGNVNGSSGHGGPSSGGGYHYNPG
                     KGPASTVGPDGEVHINITGGMEKDPPGKHHGNGGSGNGHGAGNHNSNSGGNGKTTSIPG
                     WSPDSGKPGRYLPTNKDKLIKGLIQSIDDHSGTYTIHYTGGAVATVTVPNGDVNKMNVH
                     YNIGSGPSSGNKLTRDTIKSFLEFKAENEANAVNDAISKVNDFYKELASKYGDKLEKEA
                     KALADEAKGKKIRNANEAIKAFDRYKDVLNKKFSVSDREAIAKALESLNKDQMAKQLKI
                     FGKAFGVVGEAIQWGGFISGLVKGFRTGDWNEAFISGEKIAVGKVASVMVTVAFSAMAV
                     NPIGILGFAVIMAVTSALITDERLKQLNSFINGI"
                     /name="colicin-like pore-forming protein"
     gene            5544..5732
                     /locus_tag="WIY66_RS00035"
     CDS             5544..5732
                     /locus_tag="WIY66_RS00035"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000547462.1"
                     /translation="MHIIKPQLTKLKVVFVSKGACLFISNRQKGYVDDPKRDISININN
                     SILVGLRFKLAMIKDKM"
                     /name="hypothetical protein"
     gene            6224..7243
                     /locus_tag="WIY66_RS00040"
                     /old_locus_tag="WIY66_25225"
     CDS             6224..7243
                     /locus_tag="WIY66_RS00040"
                     /old_locus_tag="WIY66_25225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001271364.1"
                     /translation="MSAALQYFEENLPHRPYHTDDLAFGLRISGKGRALLARYIQQNQP
                     HAQFWLVFDVDREGAAIDWSDRNAPAPNITVKNPVNGHAHLLYALNIAVRTAPDASVKA
                     LKYAAAVERSLCEKLCADVNYSGLICKNPFHLEWQVMEWREDAYTLDELADYLDLSASE
                     RRSIDKHYGMGRNCHLFEMTRKWAYRAIRQGWPAFSQWLEAVIQRVEMYNASLPVPLSL
                     AECRAIGKSIAKYTHRNFTPETFAQYVADTHTPEIQAARGRKGGKANSSENQSDKGKKS
                     AAVRWTANDDKRRRALDMYILGASTEDIAVAVGVSSRTIRRWMDNSGEWLTKKQIIKC"
                     /name="replication initiation protein"
     gene            complement(7504..7902)
                     /locus_tag="WIY66_RS00045"
                     /old_locus_tag="WIY66_25230"
     CDS             complement(7504..7902)
                     /locus_tag="WIY66_RS00045"
                     /old_locus_tag="WIY66_25230"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001222916.1"
                     /translation="MRISNIEWLKKRIGFIRKLGEQTARQRQIIDLLDNEAGLTEQERK
                     LLHVLATAEKNDLQAQESERKQAVQKRIEGKKQRRERNHRLFLAAGLLIEAGLVDTKTG
                     ELCYKKDRILQALKEIKYDLETSPNPDA"
                     /name="hypothetical protein"
     gene            8079..9005
                     /locus_tag="WIY66_RS00050"
                     /old_locus_tag="WIY66_25235"
     CDS             8079..9005
                     /locus_tag="WIY66_RS00050"
                     /old_locus_tag="WIY66_25235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_001736644.1"
                     /translation="MATYHLSVKFGGKGQAANHADYIERKEKYRDRQDLEYSAHGNMPE
                     WARDNPSHFWQAADQFERANGSTYRELEIALPRELTPEQRLELVQDFVRQEAGERHAWS
                     FAIHNPKASIEGGEQPHAHIMMSQRVNDGIERTPEQYFRRYNARYPERGGAKKDSGSLT
                     PTQQKEQLRELRKRWEVKHNEHMRKNGFERGFIDCRTLKEQGIERRPEVHLGFEAAGRL
                     DDAQRHDIMQKRSEPDYSRHLEQARTVGHDIMEWLDTPVKQHELVRRLQHDVAREHGFD
                     MRDRVSRQDRTEPERVKSPSRGFSMGF"
                     /name="MobA/MobL family protein"
     gene            9008..9541
                     /locus_tag="WIY66_RS00055"
                     /old_locus_tag="WIY66_25240"
     CDS             9008..9541
                     /locus_tag="WIY66_RS00055"
                     /old_locus_tag="WIY66_25240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000168774.1"
                     /translation="MASTEEKLLTLLLSVEHLQHTAMEQQKAVADSLAVARETLRGYRD
                     ISDGVAKQVRDEVRNEVQNLDVAGLIGERISQDFQRLEESVANMKANADALNRDIATIH
                     SNIVQEYNTLKGYSWKWLGGVSVAFLVMFCVLGWGMKTMLDRNYNATAAVYQKVVILED
                     KLAEKPVTGKNRKN"
                     /name="hypothetical protein"
     gene            9762..10886
                     /locus_tag="WIY66_RS00060"
                     /old_locus_tag="WIY66_25245"
     CDS             9762..10886
                     /locus_tag="WIY66_RS00060"
                     /old_locus_tag="WIY66_25245"
                     /inference="COORDINATES: protein motif:HMM:NF013211.4"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA];
                     GO:0050829 - defense response to Gram-negative bacterium
                     [Evidence IEA]; GO:0031640 - killing of cells of another
                     organism [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like pore-forming protein"
                     /protein_id="WP_021529456.1"
                     /translation="MSGGDGRGPGNTGLGHNGGKPSGNVNGSSGHGGPSSGGGYHYNPG
                     KGPASTVGPDGEVHINITGGMEKDPPGKHHGNGGSGNGHGAGNHNSNSGGNGKTTSIPG
                     WSPDSGKPGRYLPTNKDKLIKGLIQSIDDHSGTYTIHYTGGAVATVTVPNGDVNKMNVH
                     YNIGSGPSSGNKLTRDTIKSFLEFKAENEANAVNDAISKVNDFYKELASKYGDKLEKEA
                     KALADEAKGKKIRNANEAIKAFDRYKDVLNKKFSVSDREAIAKALESLNKDQMAKQLKI
                     FGKAFGVVGEAIQWGGFISGLVKGFRTGDWNEAFISGEKIAVGKVASVMVTVAFSAMAV
                     NPIGILGFAVIMAVTSALITDERLKQLNSFINGI"
                     /name="colicin-like pore-forming protein"
     Typing          762..1536
                     /name="Col156"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.392"
                     /coverage="83.0"
                     /evalue="0.0"
     Typing          6225..6999
                     /name="Col156"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.392"
                     /coverage="83.0"
                     /evalue="0.0"
     Typing          2617..3539
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.052"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          8080..9002
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.052"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttttgttttt ctatcgcttt ttgttggtta taaagtaata gactgtaaaa atcaatccaa
       61 atggaggtag tgataatata atgcatatta taaaacccca gttaacgaag ttaaaagttg
      121 tttttgttag taagggtgct tgcttattta ttagtaatag acaaaaaggg tatgtggacg
      181 atccaaaaag agatataagt ataaatataa ataattctat acttgttggg cttagattca
      241 aacttgcgat gataaaagat aaaatgtaaa aggataaggc aaggataaaa ttccttaaat
      301 agaattccat atctattttt ttcatttata aaatcctcgt tagttaaatg tttataatat
      361 tgccttactt tatccataaa tctagaagta gttatcacaa aagttacttt tttgactcgt
      421 tcgccctttt gaacggtcga aactgtttgc gaatcgcttt cgtgcatagt tatgcaacgc
      481 cctgaaagtg attctgacgc atttttctgg tttggcctgg tgtttccttg tctttttgcg
      541 ttttttgcgc cagaaagcga ctgagggcgt tttaaggggt acgtacaacg ggagttatgg
      601 taaatggatc ggatttgcgg gaaggctcga caggttttgt cgttgggggt agtgtaagcg
      661 actgaaaaac aaacgcccct gaaattcgtg tctatccgcc aagactttca cgaaaataca
      721 ggggcgatgt cggtcgataa cctggaagga atcgtaacac atgagcgccg cgcttcaata
      781 cttcgaagaa aatttacccc accgtcccta tcacacggat gatctcgctt tcggccttcg
      841 tatctccggc aaagggcgcg cgcttcttgc acggtatatc cagcagaacc agcctcatgc
      901 acagttctgg ctggtttttg acgttgaccg cgagggggct gcgattgact ggagcgaccg
      961 gaacgccccc gcgccgaaca tcaccgttaa aaatcctgtg aacggacacg ctcacctgct
     1021 ctacgcactc aacatcgccg tgagaaccgc gcctgatgcc tcggttaagg cgctgaaata
     1081 tgccgcagcg gttgaacgtt cgctgtgtga gaaactttgt gctgatgtga actacagcgg
     1141 cctgatttgc aaaaatccgt tccacctgga atggcaggtg atggagtggc gcgaggacgc
     1201 ctataccctc gatgaactgg cagattatct cgatttgagc gcctcagagc gtcgtagcat
     1261 cgataaacat tacgggatgg ggcgaaactg ccacctgttc gaaatgacgc gcaaatgggc
     1321 ttacagggcg attcgtcagg gctggccagc gttctcacag tggcttgaag cggtgatcca
     1381 gcgtgtcgaa atgtacaatg catcgcttcc cgttccgctt tcactggctg aatgtcgggc
     1441 tattggcaag agcattgcga aatacacgca caggaacttc acgccggaaa ctttcgcaca
     1501 gtatgtggct gatacgcaca cgccagaaat tcaggcagca cgcggtcgca agggcgggaa
     1561 ggccaattcg tcagaaaatc agtcggacaa agggaaaaaa agcgccgctg ttcggtggac
     1621 tgctaacgac gacaaacgtc gtagggcgct tgatatgtat atcttgggag cgtcaacgga
     1681 agatattgca gtggcggttg gtgttagcag ccggactatt cgacgctgga tggataattc
     1741 tggagaatgg ctaaccaaga aacaaataat taaatgttag ttaacaaaga agcaacacta
     1801 ccccccgttt tttgttaatg ggatgttaaa ttcgcggaca tgaacaagcc tatatcagat
     1861 aacagcgcct ttcggcgtct ttttgagcag cgggctttcc ggcggttttc tcctctcagc
     1921 ccagcaatgg tgcggcttac cgcatgattg aggtggtcgt gctcgccgca gtctcatgac
     1981 cgagcgtagc gagcgaatga gcgaggaagc accagggaac cggaacacgg atggaggcac
     2041 ttacgcgtct gggtttgggg atgtctccag atcgtactta atttccttaa gtgcctgtaa
     2101 tatcctgtct tttttatagc atagctcgcc tgtttttgtg tctaccagtc ctgcttcgat
     2161 cagtagccca gccgcgagaa agagtcggtg attgcgttct cgtcgttgtt tttttccctc
     2221 gattcgtttt tggaccgcct gttttcgttc gctctcctgt gcctgtaagt cgtttttttc
     2281 cgctgttgcc agtacgtgga ggagtttgcg ttcctgttct gtgagtcctg cttcgttgtc
     2341 gagcaggtca ataatctgtc tctgtcgtgc ggtctgttct ccgagcttcc tgatgaatcc
     2401 gatccgtttc ttcagccatt cgatgttgct gatgcgcatg ttcgtggtgc tccctggtgt
     2461 ttttttgcgg tgtgttgtgg tcgtgcagta tatcgcttgc ggtcggcggg tgcagggggt
     2521 atcttccgtg ctaattcgta aaattagaag gaagcgcact tatatgtttc tctccttcgt
     2581 cgagaaacag tgcgctcctg cggagggctg aaaccgtggc gacctatcac ctcagcgtta
     2641 agtttggtgg caagggacag gctgcaaacc atgccgatta catcgagcgc aaagagaaat
     2701 accgcgaccg tcaagatttg gaatattccg cacacggaaa catgccggaa tgggcgcgag
     2761 ataatccctc ccatttctgg caggcggctg accagtttga acgtgcaaac ggttcgactt
     2821 atcgggaact ggagatagcg ctgccccgtg aactgacacc ggaacagcgc cttgaactgg
     2881 tgcaggattt tgtacgtcag gaagctggcg aacggcatgc atggagtttt gccattcaca
     2941 atccgaaagc gagcattgag ggaggcgaac agcctcatgc gcatatcatg atgagtcagc
     3001 gtgtgaatga tggcattgaa cgtacaccgg aacagtattt ccggcgctat aacgccaggt
     3061 atcccgagcg gggaggtgcg aaaaaggatt caggaagcct gactcccact cagcaaaaag
     3121 agcagttgcg ggaattgcga aaacgctggg aggtgaagca caacgaacat atgagaaaaa
     3181 atggctttga aaggggcttc attgactgtc ggacgctgaa agaacagggc attgaacgac
     3241 gtcccgaagt gcatctgggt tttgaagctg ccggacggct tgatgatgcc cagcgtcatg
     3301 acatcatgca aaaacggtct gaaccggact attcccgcca tcttgaacag gcgcgaacgg
     3361 tcgggcatga catcatggaa tggctggaca ctccggttaa gcaacatgaa ctggtcagaa
     3421 ggctgcaaca tgatgttgcg cgggagcatg gctttgacat gagagacaga gtgagcagac
     3481 aggaccgaac tgaacctgaa cgggttaaat caccgtcacg tggattttct atgggattct
     3541 gaacatggcc agcacagaag aaaaattact cacgctcctg ttatcggtgg agcatttgca
     3601 acataccgca atggagcaac agaaagctgt tgctgattct ctggctgtgg caagggaaac
     3661 acttcgcgga tatcgggata tttctgacgg tgtggcaaaa caggtcaggg atgaagtcag
     3721 aaatgaggtg cagaatctgg acgtagcagg gctgataggt gagcgcatca gccaggattt
     3781 tcagcggctg gaagagtcag tcgcaaacat gaaggcaaac gcggatgctc tgaacaggga
     3841 tattgcgaca attcacagca atatcgtgca ggaatacaac acccttaaag ggtatagctg
     3901 gaaatggctg ggtggggtgt cagtggcttt tctagttatg ttctgtgtgc tcggatgggg
     3961 aatgaaaaca atgctcgaca ggaactacaa cgccacagcg gcggtgtatc agaaagttgt
     4021 gatactggaa gataaactgg cggaaaaacc tgtcacgggt aagaaccgga aaaactgacg
     4081 cgcttcgctt gtccaacgcc tcacggacag cgaaaggatt tcgcgttccg ttcaccgttt
     4141 tcatgagtga ttcctccgaa ctgccaaaaa atatccctcc ctgacttgac agaaaaaata
     4201 atggcgagta ctttttgatc tgtacataaa accagtggtt ttatgtacag tattaactat
     4261 gtaattaatt gttttaacga ttaaaagagg gaatttttat gagtggtgga gatggtcgtg
     4321 gccctggtaa tacagggctt ggacataacg gtggtaaacc cagtggaaac gtgaatggct
     4381 catctggaca tggaggacca tcatctggcg gtgggtatca ttacaatccg ggaaaaggtc
     4441 ctgcaagcac tgtaggtcct gacggggagg tgcatatcaa cattaccggt ggtatggaaa
     4501 aagatcctcc aggaaaacat cacggtaatg gtggctcagg taatggtcac ggtgctggaa
     4561 atcataacag caattcaggc ggcaatggaa aaacaacgtc tattcctgga tggagccctg
     4621 actctgggaa acctggcaga tatttaccga caaataaaga taagttaatt aagggactta
     4681 ttcagtcaat agatgaccat tctggaacgt acactatcca ttatactggt ggtgcagtag
     4741 ctacagtaac tgtaccaaac ggtgatgtga ataaaatgaa tgttcactat aatatcggta
     4801 gtgggccgtc atcaggtaat aaactgactc gtgatactat aaaaagcttt ttagaattca
     4861 aggcagaaaa tgaagctaat gctgtaaatg atgcaataag caaagttaat gacttttata
     4921 aagagttagc atcaaaatac ggcgataagt tggagaaaga agccaaggca ctagccgatg
     4981 aagctaaagg gaaaaaaatt cgcaatgcta atgaggcgat taaagccttt gataggtaca
     5041 aggatgtgct taataagaaa ttcagcgtat ccgaccgaga agcgattgca aaagcactgg
     5101 agtctcttaa taaagatcaa atggctaaac agttaaaaat ttttggtaag gcctttggtg
     5161 tcgtaggtga ggctattcag tgggggggat ttatcagtgg cttagttaaa ggattcagaa
     5221 ctggtgactg gaatgaggct tttataagcg gggaaaaaat cgcagtcggc aaggtagcat
     5281 ctgttatggt tacagtggca tttagtgcta tggcagtaaa tcctattggt attttagggt
     5341 ttgcagtaat tatggcagtg actagtgcct taattacaga tgaaaggctg aaacaactaa
     5401 acagctttat taacggcatt taataaacaa aaggtcgtac cgtttgatat ggtatgacct
     5461 ttattttgtt tttctatcgc tttttgttgg ttataaagta atagactgta aaaatcaatc
     5521 caaatggagg tagtgataat ataatgcata ttataaaacc ccagttaacg aagttaaaag
     5581 ttgtttttgt tagtaagggt gcttgcttat ttattagtaa tagacaaaaa gggtatgtgg
     5641 acgatccaaa aagagatata agtataaata taaataattc tatacttgtt gggcttagat
     5701 tcaaacttgc gatgataaaa gataaaatgt aaaaggataa ggcaaggata aaattcctta
     5761 aatagaattc catatctatt tttttcattt ataaaatcct cgttagttaa atgtttataa
     5821 tattgcctta ctttatccat aaatctagaa gtagttatca caaaagttac ttttttgact
     5881 cgttcgccct tttgaacggt cgaaactgtt tgcgaatcgc tttcgtgcat agttatgcaa
     5941 cgccctgaaa gtgattctga cgcatttttc tggtttggcc tggtgtttcc ttgtcttttt
     6001 gcgttttttg cgccagaaag cgactgaggg cgttttaagg ggtacgtaca acgggagtta
     6061 tggtaaatgg atcggatttg cgggaaggct cgacaggttt tgtcgttggg ggtagtgtaa
     6121 gcgactgaaa aacaaacgcc cctgaaattc gtgtctatcc gccaagactt tcacgaaaat
     6181 acaggggcga tgtcggtcga taacctggaa ggaatcgtaa cacatgagcg ccgcgcttca
     6241 atacttcgaa gaaaatttac cccaccgtcc ctatcacacg gatgatctcg ctttcggcct
     6301 tcgtatctcc ggcaaagggc gcgcgcttct tgcacggtat atccagcaga accagcctca
     6361 tgcacagttc tggctggttt ttgacgttga ccgcgagggg gctgcgattg actggagcga
     6421 ccggaacgcc cccgcgccga acatcaccgt taaaaatcct gtgaacggac acgctcacct
     6481 gctctacgca ctcaacatcg ccgtgagaac cgcgcctgat gcctcggtta aggcgctgaa
     6541 atatgccgca gcggttgaac gttcgctgtg tgagaaactt tgtgctgatg tgaactacag
     6601 cggcctgatt tgcaaaaatc cgttccacct ggaatggcag gtgatggagt ggcgcgagga
     6661 cgcctatacc ctcgatgaac tggcagatta tctcgatttg agcgcctcag agcgtcgtag
     6721 catcgataaa cattacggga tggggcgaaa ctgccacctg ttcgaaatga cgcgcaaatg
     6781 ggcttacagg gcgattcgtc agggctggcc agcgttctca cagtggcttg aagcggtgat
     6841 ccagcgtgtc gaaatgtaca atgcatcgct tcccgttccg ctttcactgg ctgaatgtcg
     6901 ggctattggc aagagcattg cgaaatacac gcacaggaac ttcacgccgg aaactttcgc
     6961 acagtatgtg gctgatacgc acacgccaga aattcaggca gcacgcggtc gcaagggcgg
     7021 gaaggccaat tcgtcagaaa atcagtcgga caaagggaaa aaaagcgccg ctgttcggtg
     7081 gactgctaac gacgacaaac gtcgtagggc gcttgatatg tatatcttgg gagcgtcaac
     7141 ggaagatatt gcagtggcgg ttggtgttag cagccggact attcgacgct ggatggataa
     7201 ttctggagaa tggctaacca agaaacaaat aattaaatgt tagttaacaa agaagcaaca
     7261 ctaccccccg ttttttgtta atgggatgtt aaattcgcgg acatgaacaa gcctatatca
     7321 gataacagcg cctttcggcg tctttttgag cagcgggctt tccggcggtt ttctcctctc
     7381 agcccagcaa tggtgcggct taccgcatga ttgaggtggt cgtgctcgcc gcagtctcat
     7441 gaccgagcgt agcgagcgaa tgagcgagga agcaccaggg aaccggaaca cggatggagg
     7501 cacttacgcg tctgggtttg gggatgtctc cagatcgtac ttaatttcct taagtgcctg
     7561 taatatcctg tcttttttat agcatagctc gcctgttttt gtgtctacca gtcctgcttc
     7621 gatcagtagc ccagccgcga gaaagagtcg gtgattgcgt tctcgtcgtt gtttttttcc
     7681 ctcgattcgt ttttggaccg cctgttttcg ttcgctctcc tgtgcctgta agtcgttttt
     7741 ttccgctgtt gccagtacgt ggaggagttt gcgttcctgt tctgtgagtc ctgcttcgtt
     7801 gtcgagcagg tcaataatct gtctctgtcg tgcggtctgt tctccgagct tcctgatgaa
     7861 tccgatccgt ttcttcagcc attcgatgtt gctgatgcgc atgttcgtgg tgctccctgg
     7921 tgtttttttg cggtgtgttg tggtcgtgca gtatatcgct tgcggtcggc gggtgcaggg
     7981 ggtatcttcc gtgctaattc gtaaaattag aaggaagcgc acttatatgt ttctctcctt
     8041 cgtcgagaaa cagtgcgctc ctgcggaggg ctgaaaccgt ggcgacctat cacctcagcg
     8101 ttaagtttgg tggcaaggga caggctgcaa accatgccga ttacatcgag cgcaaagaga
     8161 aataccgcga ccgtcaagat ttggaatatt ccgcacacgg aaacatgccg gaatgggcgc
     8221 gagataatcc ctcccatttc tggcaggcgg ctgaccagtt tgaacgtgca aacggttcga
     8281 cttatcggga actggagata gcgctgcccc gtgaactgac accggaacag cgccttgaac
     8341 tggtgcagga ttttgtacgt caggaagctg gcgaacggca tgcatggagt tttgccattc
     8401 acaatccgaa agcgagcatt gagggaggcg aacagcctca tgcgcatatc atgatgagtc
     8461 agcgtgtgaa tgatggcatt gaacgtacac cggaacagta tttccggcgc tataacgcca
     8521 ggtatcccga gcggggaggt gcgaaaaagg attcaggaag cctgactccc actcagcaaa
     8581 aagagcagtt gcgggaattg cgaaaacgct gggaggtgaa gcacaacgaa catatgagaa
     8641 aaaatggctt tgaaaggggc ttcattgact gtcggacgct gaaagaacag ggcattgaac
     8701 gacgtcccga agtgcatctg ggttttgaag ctgccggacg gcttgatgat gcccagcgtc
     8761 atgacatcat gcaaaaacgg tctgaaccgg actattcccg ccatcttgaa caggcgcgaa
     8821 cggtcgggca tgacatcatg gaatggctgg acactccggt taagcaacat gaactggtca
     8881 gaaggctgca acatgatgtt gcgcgggagc atggctttga catgagagac agagtgagca
     8941 gacaggaccg aactgaacct gaacgggtta aatcaccgtc acgtggattt tctatgggat
     9001 tctgaacatg gccagcacag aagaaaaatt actcacgctc ctgttatcgg tggagcattt
     9061 gcaacatacc gcaatggagc aacagaaagc tgttgctgat tctctggctg tggcaaggga
     9121 aacacttcgc ggatatcggg atatttctga cggtgtggca aaacaggtca gggatgaagt
     9181 cagaaatgag gtgcagaatc tggacgtagc agggctgata ggtgagcgca tcagccagga
     9241 ttttcagcgg ctggaagagt cagtcgcaaa catgaaggca aacgcggatg ctctgaacag
     9301 ggatattgcg acaattcaca gcaatatcgt gcaggaatac aacaccctta aagggtatag
     9361 ctggaaatgg ctgggtgggg tgtcagtggc ttttctagtt atgttctgtg tgctcggatg
     9421 gggaatgaaa acaatgctcg acaggaacta caacgccaca gcggcggtgt atcagaaagt
     9481 tgtgatactg gaagataaac tggcggaaaa acctgtcacg ggtaagaacc ggaaaaactg
     9541 acgcgcttcg cttgtccaac gcctcacgga cagcgaaagg atttcgcgtt ccgttcaccg
     9601 ttttcatgag tgattcctcc gaactgccaa aaaatatccc tccctgactt gacagaaaaa
     9661 ataatggcga gtactttttg atctgtacat aaaaccagtg gttttatgta cagtattaac
     9721 tatgtaatta attgttttaa cgattaaaag agggaatttt tatgagtggt ggagatggtc
     9781 gtggccctgg taatacaggg cttggacata acggtggtaa acccagtgga aacgtgaatg
     9841 gctcatctgg acatggagga ccatcatctg gcggtgggta tcattacaat ccgggaaaag
     9901 gtcctgcaag cactgtaggt cctgacgggg aggtgcatat caacattacc ggtggtatgg
     9961 aaaaagatcc tccaggaaaa catcacggta atggtggctc aggtaatggt cacggtgctg
    10021 gaaatcataa cagcaattca ggcggcaatg gaaaaacaac gtctattcct ggatggagcc
    10081 ctgactctgg gaaacctggc agatatttac cgacaaataa agataagtta attaagggac
    10141 ttattcagtc aatagatgac cattctggaa cgtacactat ccattatact ggtggtgcag
    10201 tagctacagt aactgtacca aacggtgatg tgaataaaat gaatgttcac tataatatcg
    10261 gtagtgggcc gtcatcaggt aataaactga ctcgtgatac tataaaaagc tttttagaat
    10321 tcaaggcaga aaatgaagct aatgctgtaa atgatgcaat aagcaaagtt aatgactttt
    10381 ataaagagtt agcatcaaaa tacggcgata agttggagaa agaagccaag gcactagccg
    10441 atgaagctaa agggaaaaaa attcgcaatg ctaatgaggc gattaaagcc tttgataggt
    10501 acaaggatgt gcttaataag aaattcagcg tatccgaccg agaagcgatt gcaaaagcac
    10561 tggagtctct taataaagat caaatggcta aacagttaaa aatttttggt aaggcctttg
    10621 gtgtcgtagg tgaggctatt cagtgggggg gatttatcag tggcttagtt aaaggattca
    10681 gaactggtga ctggaatgag gcttttataa gcggggaaaa aatcgcagtc ggcaaggtag
    10741 catctgttat ggttacagtg gcatttagtg ctatggcagt aaatcctatt ggtattttag
    10801 ggtttgcagt aattatggca gtgactagtg ccttaattac agatgaaagg ctgaaacaac
    10861 taaacagctt tattaacggc atttaataaa caaaaggtcg taccgtttga tatggtatga
    10921 ccttta
//
